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At least 361 records · Page 20

The NASA Open Science Data Repository: Biomedical Fair Data, Analysis Tools, User Communities, Publications, and Discoveries for Deep Space Missions

Increased biomedical risks and challenges associated with deep space missions require new knowledge discovery, new health countermeasures, and development of novel ecosystems, life support, crop production, and biomedical support capabilities. To meet NASA’s Moon to Mars strategic program goals for Human and Biological Sciences, findable, accessible, interoperable, reusable (FAIR), and maximally open-access data is going to be required to enable humanity to thrive in deep space. Indeed, this cornerstone perspective on FAIR and maximally open access data was also recommended in the recent 2023-2032 Decadal Survey from the National Academies of Sciences, Engineering, and Medicine. The NASA Open Science Data Repository (OSDR) is a maximally open access and FAIR database, and meets various scientific, technical, and operational spaceflight needs. It offers public users and submitters the ability to upload, download, search, share, analyze, and visualize data across ‘omics, physiological, phenotypic, behavioral, bioimaging, video, and environmental monitoring telemetry datasets. OSDR includes NASA GeneLab, NASA Ames Life Sciences Data Archive, and the NASA Biological Institutional Scientific Collection. OSDR has >455 studies with datasets from model organisms and non-NASA human astronauts. There are ~12 datasets from the Inspiration 4 (I4) mission, spanning metagenomics, comprehensive metabolic panels, clonal hematopoiesis, spatial transcriptomics, proteomics, and cytokine panels. In the interest of data privacy, two I4 datasets have raw FASTQ and FASTA files relating to the epitranscriptome, and a new request feature is live in OSDR (with a backend review process established) which was developed based on industry norms. OSDR also recently began a collaboration with the European Space Agency (ESA) to scientifically curate and make available >200 terabytes of human and model organism space-relevant data. The OSDR submission portal is designed to ingest and curate ~25 ‘omics assay data types, and ~50 physiological-phenotypic-imaging assay data types, spanning ultrasonography, micro-computed tomography, histology, morphometric photography, rebound tonometry, gait analysis, optical coherence tomography, novel object recognition, flow cytometry, and immunohistochemistry. A suite of analysis tools are available for OSDR users including: 1) an Environmental Data Application to compare radiation, CO2, relative humidity, temperature, and other telemetry across missions and subjects, 2) the RadLab database, a collaboration between NASA, ESA, the German and Italian Space Agencies, and the Bulgarian Academy of Sciences, which compiles radiation measurements relevant to human spaceflight and provides tools for accessing and manipulating the data, and 3) a Multi-study visualization tool which enables users to look across and combine GeneLab’s omics datasets across different experiments and missions. There are ~600 volunteer OSDR Analysis Working Group (AWG) members who: 1) provide feedback on scientific standards for reuse (subject and assay metadata; processing pipelines; dataset formats and uniformed structures for machine-readability), and 2) collaborate to mine-reuse OSDR data conducting scientific analysis. OSDR has enabled 60 publications as of September 2023, many directly from AWG collaborations most notably the Cell Press package in 2020. Lastly, there are at least 15 articles which mine OSDR data part of a package of ~50 articles across Nature Portfolio with research stemming from I4, the Japan Aerospace Exploration Agency, NASA Space Biology, and the NASA Human Research Program.

space biology↗

Propellant-Flow-Actuated Rocket Engine Igniter

A rocket engine igniter has been created that uses a pneumatically driven hammer that, by specialized geometry, is induced into an oscillatory state that can be used to either repeatedly impact a piezoelectric crystal with sufficient force to generate a spark capable of initiating combustion, or can be used with any other system capable of generating a spark from direct oscillatory motion. This innovation uses the energy of flowing gaseous propellant, which by means of pressure differentials and kinetic motion, causes a hammer object to oscillate. The concept works by mass flows being induced through orifices on both sides of a cylindrical tube with one or more vent paths. As the mass flow enters the chamber, the pressure differential is caused because the hammer object is supplied with flow on one side and the other side is opened with access to the vent path. The object then crosses the vent opening and begins to slow because the pressure differential across the ball reverses due to the geometry in the tube. Eventually, the object stops because of the increasing pressure differential on the object until all of the kinetic energy has been transferred to the gas via compression. This is the point where the object reverses direction because of the pressure differential. This behavior excites a piezoelectric crystal via direct impact from the hammer object. The hammer strikes a piezoelectric crystal, then reverses direction, and the resultant high voltage created from the crystal is transferred via an electrode to a spark gap in the ignition zone, thereby providing a spark to ignite the engine. Magnets, or other retention methods, might be employed to favorably position the hammer object prior to start, but are not necessary to maintain the oscillatory behavior. Various manifestations of the igniter have been developed and tested to improve device efficiency, and some improved designs are capable of operation at gas flow rates of a fraction of a gram per second (0.001 lb/s) and pressure drops on the order of 30 to 50 kilopascal (a few psi). An analytical model has been created and tested in conjunction with a precisely calibrated reference model. The analytical model accurately captures the overall behavior of this innovation. The model is a simple "volume-orifice" concept, with each chamber considered a single temperature and pressure "node" connected to adjacent nodes, or to vent paths through flow control orifices. Mass and energy balances are applied to each node, with gas flow predicted using simple compressible flow equations.

Wollen, Mark↗

The Namibia Early Flood Warning System, A CEOS Pilot Project

Over the past year few years, an international collaboration has developed a pilot project under the auspices of Committee on Earth Observation Satellite (CEOS) Disasters team. The overall team consists of civilian satellite agencies. For this pilot effort, the development team consists of NASA, Canadian Space Agency, Univ. of Maryland, Univ. of Colorado, Univ. of Oklahoma, Ukraine Space Research Institute and Joint Research Center(JRC) for European Commission. This development team collaborates with regional , national and international agencies to deliver end-to-end disaster coverage. In particular, the team in collaborating on this effort with the Namibia Department of Hydrology to begin in Namibia . However, the ultimate goal is to expand the functionality to provide early warning over the South Africa region. The initial collaboration was initiated by United Nations Office of Outer Space Affairs and CEOS Working Group for Information Systems and Services (WGISS). The initial driver was to demonstrate international interoperability using various space agency sensors and models along with regional in-situ ground sensors. In 2010, the team created a preliminary semi-manual system to demonstrate moving and combining key data streams and delivering the data to the Namibia Department of Hydrology during their flood season which typically is January through April. In this pilot, a variety of moderate resolution and high resolution satellite flood imagery was rapidly delivered and used in conjunction with flood predictive models in Namibia. This was collected in conjunction with ground measurements and was used to examine how to create a customized flood early warning system. During the first year, the team made use of SensorWeb technology to gather various sensor data which was used to monitor flood waves traveling down basins originating in Angola, but eventually flooding villages in Namibia. The team made use of standardized interfaces such as those articulated under the Open Cloud Consortium (OGC) Sensor Web Enablement (SWE) set of web services was good [1][2]. However, it was discovered that in order to make a system like this functional, there were many performance issues. Data sets were large and located in a variety of location behind firewalls and had to be accessed across open networks, so security was an issue. Furthermore, the network access acted as bottleneck to transfer map products to where they are needed. Finally, during disasters, many users and computer processes act in parallel and thus it was very easy to overload the single string of computers stitched together in a virtual system that was initially developed. To address some of these performance issues, the team partnered with the Open Cloud Consortium (OCC) who supplied a Computation Cloud located at the University of Illinois at Chicago and some manpower to administer this Cloud. The Flood SensorWeb [3] system was interfaced to the Cloud to provide a high performance user interface and product development engine. Figure 1 shows the functional diagram of the Flood SensorWeb. Figure 2 shows some of the functionality of the Computation Cloud that was integrated. A significant portion of the original system was ported to the Cloud and during the past year, technical issues were resolved which included web access to the Cloud, security over the open Internet, beginning experiments on how to handle surge capacity by using the virtual machines in the cloud in parallel, using tiling techniques to render large data sets as layers on map, interfaces to allow user to customize the data processing/product chain and other performance enhancing techniques. The conclusion reached from the effort and this presentation is that defining the interoperability standards in a small fraction of the work. For example, once open web service standards were defined, many users could not make use of the standards due to security restrictions. Furthermore, once an interoperable sysm is functional, then a surge of users can render a system unusable, especially in the disaster domain.

Mandl, Daniel↗

mzPeak: Designing a Scalable, Interoperable, and Future-Ready Mass Spectrometry Data Format

Advances in mass spectrometry (MS) instrumentation, such as higher resolution, faster scan speeds, and improved sensitivity, have significantly increased the volume and complexity of data. The growing adoption of imaging and ion mobility further amplifies these challenges across MS-based omics fields, including proteomics, metabolomics, and lipidomics. While these technologies unlock new possibilities, they also present significant challenges in data management, storage, and accessibility. Existing open formats, such as the XML-based community standards mzML and imzML, struggle to meet the demands of modern MS workflows due to their large file sizes, slow data access, and limited metadata support. Vendor-specific formats, while optimized for proprietary instruments, lack interoperability, comprehensive metadata support and long-term archival reliability. This white paper lays the groundwork for mzPeak, a next-generation community data format designed to address these challenges and support high-throughput, multi-dimensional MS workflows. By adopting a hybrid model that combines efficient binary storage for numerical data and both human and machine-readable metadata storage, mzPeak will reduce file sizes, accelerate data access, and offer a scalable, adaptable solution for evolving MS technologies. For researchers, mzPeak will enable enhanced interoperability across platforms, seamless support for complex workflows including ion mobility and MS imaging, and faster data access compared to existing community formats such as mzML. Its design will ensure data is managed in compliance with regulatory standards, essential for applications such as precision medicine and chemical safety, where long-term data integrity and accessibility are critical. For vendors, mzPeak provides a streamlined, open alternative to proprietary formats, reducing the burden of regulatory compliance while aligning with the industry's push for transparency and standardization. By offering a high-performance, interoperable solution, mzPeak positions vendors to meet customer demands for sustainable data management tools which will be able to handle emerging and future data types and workflows. mzPeak aspires to become the cornerstone of MS data management, empowering researchers, vendors, and developers to innovate and collaborate more effectively.

data formats↗

Solar Flares, Type III Radio Bursts, CMEs, and Energetic Particles

Despite the fact that it has been well known since the earliest observations that solar energetic particle events are well associated with solar flares it is often considered that the association is not physically significant. Instead, in large events, the particles are considered to be only accelerated at a shock driven by the coronal mass ejection (CME) that is also always present. If particles are accelerated in the associated flare, it is claimed that such particles do not find access to open field lines and therefore do not escape from the low corona. However recent work has established that long lasting type III radio bursts extending to low frequencies are associated with all prompt solar particle events. Such bursts establish the presence of open field lines. Furthermore, tracing the radio bursts to the lowest frequencies, generated near the observer, shows that the radio producing electrons gain access to a region of large angular extent. It is likely that the electrons undergo cross field transport and it seems reasonable that ions do also. Such observations indicate that particle propagation in the inner heliosphere is not yet fully understood. They also imply that the contribution of flare particles in major particle events needs to be properly addressed.

Cane, H. V.↗

Refrigerator Door-in-Door Opening Controller

Door-in-door refrigerators are becoming increasingly popular on the market. To save energy, items that are most frequently used are stored between doors. Thus only the outer door needs to be opened for access. This invention is used for standard energy performance laboratory tests for these kinds of refrigerators. In conjunction with an automated refrigerator door opener, it allows the refrigerator door opener to open either the outer door only or both inner and outer doors together.

Wang, Duo↗

Overview of Two Decision-Support Systems for Viticulture

Sustainable water management is one of the most challenging issues of our time, especially in the arid western U.S. Adequate water supplies are crucial to maintaining the health of communities, rivers, and wildlife, and nothing is more important to agriculture’s ability to produce food for the world’s growing population. Maximizing the benefits of our water supplies requires careful measurement of their availability and use. For irrigated agriculture, satellite-based estimates of evapotranspiration (ET) provide a measure of the water used to grow food — the biggest share of water consumption in most arid environments around the world. However, access to ET data has been limited and expensive, keeping it out of the hands of most water users and decision-makers. OpenET provides open, easily accessible satellite-based ET data for water management support. The OpenET collaborative includes leading national and international experts in remote sensing of ET, cloud computing, and water policy, partnered with nationally recognized web development teams and leaders in the western agriculture and water management communities. The system can be accessed at https://openetdata.org/.

Overview↗

Tokenized Data for FORGE Foundation Models

This dataset comprises a vast corpus of 257 billion tokens, accompanied by the corresponding vocabulary file employed in the pre-training of FORGE foundation models. The primary data source for this corpus is scientific documents derived from diverse origins, and they have been tokenized using the Hugging Face BPE tokenizer. Further details about this research can be found in the publication titled FORGE: Pre-Training Open Foundation Models for Science authored by Junqi Yin, Sajal Dash, Feiyi Wang, and Mallikarjun (Arjun) Shankar, presented at SC'23. The data tokenization pipeline and resulting artifacts use CORE data [Ref: Knoth, P., and Zdrahal, Z. (2012). CORE: three access levels to underpin open access. D-Lib Magazine, 18(11/12)]. For use of these data sets for any purpose, please follow the guidelines provided in https://core.ac.uk/terms .

Yin, Junqi↗

FAIR Assessments

Presentation on Findable Accessible Interoperable and Reusable (FAIR) Assessment approaches for data.

FAIR↗

ELM-free H-mode phase and decoupling of peeling–ballooning stability boundary in the MAST Upgrade tokamak

A linear magnetohydrodynamic (MHD) peeling–ballooning stability analysis of the edge-localized mode (ELM)-free phase of a MAST Upgrade (MAST-U) H-mode plasma is presented. In contrast to other similar discharges, #47018 is found to have a significantly higher and wider pedestal during its ELM-free H-mode phase that lasts for approximately 80 ms; this is made possible by the reduced core MHD mode activity on the q = 2 surface. During this period, there is sustained decoupling of peeling and ballooning branches of the stability boundary on J–α space, opening an access channel to the second stability regime with higher peaks in pedestal current density $J_{\mathrm{N,ped}}$ and pressure gradient (α). Such decoupling of the stability boundary has not previously been observed in MAST-U H-modes, and if such a condition can be readily reproduced, it opens a wide range of opportunities for MAST-U to explore low-collisionality peeling-limited pedestal regimes as well as advanced scenarios such as quiescent H-modes that are relevant to future reactors such as STEP and ITER.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Multiple Hub Network Choice in the Liberalized European Market

A key question that so far has received relatively little attention in the germane literature is that of the changes at various airports as a result of the EU liberalization policies. That is, presently, most major European airports still benefit from the so-called home-carrier phenomenon where the country's publicly or semi-publicly owned carrier uses the country's main airport as its gateway hub and, consequently, the home-carrier is also the principal user of this airport (in terms of proportion of total aircraft movements, number of passengers transported, connections, slots ownership, etc.). The country's main airport has substantially benefited from these monopoly conditions of airline captivity, strongly determined by the bilateral system of international air transport regulation. Therefore, European major airports were used to operate in essentially different markets, compared to the increasingly competitive markets of their home based carriers. This partly explains relative stability of transport volumes and financial results of European major airports compared to the relatively volatile financial results of most European national airlines. However, the liberalization of European aviation is likely to change this situation. Market access is open now to all community carriers, i.e. carriers with majority ownership and effective control in the hands of EU citizens. Ticket prices are free, governments can only intervene in case of dumping or excessive pricing. A community airline can choose its seat in any of the 15 member states. Licensing procedures are harmonized between member states. In the last few months community carriers have had unrestricted route access within the EU. Most probably this development will be extended to countries inside and outside Europe. Last year the European Commission got the mandate to start negotiations with 10 other European countries. In the meantime the EC has also started negotiations with the USA on so-called soft rights. In the meantime, open skies agreements have been concluded between the USA and most of the EU member states to facilitate strategic alliances between airlines of the states involved. As a result of this on-going liberalization the model of the single 'national' carrier using the national home base as its single hub for the designated third, fourth and sixth freedom operations will stepwise disappear. Within the EU the concept of the national carrier has already been replaced by that of the community carrier. State ownership in more and more European carriers is reduced. On the longer run mergers or even bankruptcy will further undermine the "single national carrier - single national hub" model in Europe. In the meantime, strategic alliances between national carriers in Europe will already reduce the airlines' loyalty to a single airport. Profit maximization and accountability to share holders will supersede the loyalty of these newly emerging alliances, probably looking for the opportunities of a multiple hub network to adequately cover the whole European market. As a consequence, some European airports might see a substantial decline in arriving, departing and transfer traffic, thus in revenues and financial solvency, as well as in their connection to other inter-continental and intra-European destinations. At the same time, other airports might realize a significant increase in traffic as they will be sought after by the profit maximizing airlines as their major gateway hubs. Which will be the losing airports and which will be the winning ones? Can airports anticipate the actions of airlines in deregulated markets and utilize policies which will improve their relative position? If so, what should be these anticipatory policies? These questions become the more urgent, since an increasing number of major European airports will be privatized in the near future. Although increasing airport congestion in Europe will also be reflected in a growing demand pressure for airport slots, this is not a guarantee for a stable transport volume growth of individual airports. The more volatile the market is, the more vulnerable privatized airports become. Therefore, the main issue of this study is the analysis of the opportunities of major European airports to become a central hub as a result of the network choices made by the new European airlines in a completely liberalized market. In a previous study (Berechman and de Wit, 1996), we already explored the potential of Amsterdam Airport Schiphol of becoming the major West-European hub, once European aviation markets are deregulated. A major hindrance of that study was the use of a single hub-and-spoke network. For example that model could not analyze the viability of different combinations of European hubs within a multiple hub network of alternative airline alliances. In this study, we have formulated the model of a multi-hub network where two West-European airports are used for inter-continental and intra-European travel to enable a more realistic analysis of hub choice. Like the previous one also this multi-hub model is primarily used to assess the potential ability of Amsterdam Airport Schiphol for becoming a major West-European hub. Thus, in particular, the policy tests focus on this airport in a double hub network.

Berechman, Joseph↗

NASA’s Earth System Observatory Formulation Progress

The 2017 Earth Science Decadal Survey by the National Academies of Science, Engineering, and Medicine identified five foundational observations, or Designated Observables (DO), to be implemented as missions by NASA. To address these five DO areas – Surface Biology and Geology; Mass Change; Aerosols; Cloud, Convection, and Precipitation; and Surface Deformation and Change – NASA is developing the Earth System Observatory (ESO) as an array of Earth-focused, interconnected satellite missions. The ESO will build on the strong history of international partnerships in NASA Earth science, with initial participation and collaboration on these missions across space agency partners including the Japanese Aerospace Exploration Agency (JAXA), Centre National D'Etudes Spatiales (CNES), Canadian Space Agency (CSA), Deutsches Zentrum für Luft- und Raumfahrt (DLR), and Agenzia Spaziale Italiana (ASI). Targeting launch dates in the late 2020s and early 2030s, the ESO will work as a single observatory, with each satellite in the ESO delivering its own valuable information, but taken together, the data and imagery will provide the global community with a multidimensional, holistic view of the Earth. In addition to furthering the world’s scientific knowledge, data gathered by ESO missions will provide actionable science to inform decisions related to climate change, disaster mitigation, and wildfires, improve real-time agricultural processes, and many other applications. This paper will provide an overview of the ESO development activities, as well as an update on the individual ESO missions currently in formulation – Atmosphere Observing System, Gravity Recovery and Climate Experiment-Continuity, and Surface Biology and Geology – including current mission architectures and concepts, international partner collaboration, science community engagement, and applications efforts, as well as how ESO data will be freely open and accessible to users all over the world.

NASA Earth Science↗

Discovery of spontaneous de-interpenetration through charged point-point repulsions

Entanglement is an energetically favorable occurrence, pervasive in both nature and synthetic systems, where networks prefer to entwine with one another rather than remain open and accessible. As a result of entanglement, valuable internal pore space, useful for applications such as catalysis, storage, and sensing, is lost. Here, we detail our discovery of a phenomenon termed “charged point-point repulsion,” which energetically favors dis-entanglement, transforming a densely packed uranium-based framework with 14.2 and 19.8 Å pores into an open material with 40.7 Å pores and record-high void fraction and pore volume. We anticipate that the phenomenon described in this work could be widely generalized for the direct and systematic production of non-entangled structures with an abundance of valuable pore space and far-reaching practical importance. More fundamentally, this study compels a re-evaluation of the thermodynamics of porosity.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Machine Learning–Guided Boolean Matrix Inference for Real-Time O-RAN Conflict Detection

Open Radio Access Networks (O-RAN) are emerging, software-driven cellular architectures that promote flexibility by enabling components from different vendors to interoperate. Multiple control applications called xApps can independently adjust network parameters in near real time, often without awareness of each other's actions. This creates a system highly prone to unintended conflicts and performance degradation due to the inherent complexity of such openness. To model such systems and ultimately prevent or mitigate xApp conflicts, it is essential to understand the dynamic relationships between xApps (A), the control parameters they adjust (P), and the resulting KPI responses (K). While the mappings from A to P and from K to A can often be derived from xApp specifications, the relationship from P to K is typically hidden within the system’s dynamics and must be inferred from observed data. We propose a novel data-driven Boolean inference framework that uncovers the hidden P?K dependencies using machine learning and interpretable rule induction. Continuous parameters and KPIs are first binarized using decision tree classifiers, and a binary influence matrix L is then inferred by solving Boolean matrix equations over time. This compact representation improves interpretability and enables real-time tracking of dynamically evolving parameter-KPI dependencies. We demonstrate the effectiveness of our method in a realistic mobile handover scenario, where it accurately recovers the underlying logic and enables proactive conflict detection.

42 - ENGINEERING↗

Unveiling hidden physics at the LHC

The field of particle physics is at the crossroads. The discovery of a Higgs-like boson completed the Standard Model (SM), but the lacking observation of convincing resonances Beyond the SM (BSM) offers no guidance for the future of particle physics. On the other hand, the motivation for New Physics has not diminished and is, in fact, reinforced by several striking anomalous results in many experiments. Here we summarise the status of the most significant anomalies, including the most recent results for the flavour anomalies, the multi-lepton anomalies at the LHC, the Higgs-like excess at around 96 GeV, and anomalies in neutrino physics, astrophysics, cosmology, and cosmic rays. While the LHC promises up to 4 ab –1 of integrated luminosity and far-reaching physics programmes to unveil BSM physics, we consider the possibility that the latter could be tested with present data, but that systemic shortcomings of the experiments and their search strategies may preclude their discovery for several reasons, including: final states consisting in soft particles only, associated production processes, QCD-like final states, close-by SM resonances, and SUSY scenarios where no missing energy is produced. New search strategies could help to unveil the hidden BSM signatures, devised by making use of the CERN open data as a new testing ground. We discuss the CERN open data with its policies, challenges, and potential usefulness for the community. We showcase the example of the CMS collaboration, which is the only collaboration regularly releasing some of its data. We find it important to stress that individuals using public data for their own research does not imply competition with experimental efforts, but rather provides unique opportunities to give guidance for further BSM searches by the collaborations. Wide access to open data is paramount to fully exploit the LHCs potential.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Hydrologic Model Data for the East Fork Poplar Creek Watershed Simulated with the Advanced Terrestrial Simulator (ATS): Streamflow and Network Expansion–Contraction Dynamics

This dataset supports hydrologic modeling and stream network expansion–contraction analysis for the East Fork Poplar Creek (EFPC) Watershed in Tennessee. It includes a Jupyter notebook for model setup, model configuration files, simulation outputs, and derived products used to evaluate model performance and investigate stream dynamics under varying hydrologic conditions. The dataset was generated using the Watershed Workflow Python package and the Advanced Terrestrial Simulator (ATS), enabling integrated surface–subsurface hydrologic simulations using a stream-aligned mesh. Outputs include high-resolution time series of streamflow, active network length, water table depth, and related hydrologic variables. Also included are spatially explicit stream persistency indices and classifications of reaches as perennial or non-perennial. These data facilitate reproducibility and support further research on stream intermittency and variability in network extent.The model data archive is organized in following directories:1) model_setup_inputsContains the Watershed Workflow Jupyter notebooks (accessed through any open source code editor), selected input datasets, and resulting ATS input files, including XML files (access through any open source code editor), computational mesh (.exo files can be viewed using Paraview), and meteorological forcing files (.h5 files can be accessed through h5py python package and HDFView open source software). 2) model_outputsIncludes ATS simulation outputs relevant to this study. Time series of spatially integrated or averaged variables (e.g., streamflow, water table depth) are provided as CSV files. Select spatial fields (e.g., ponded depth and water table depth) are saved as pickled Python objects to reduce file size, and can be accessed through pickle package in Python. Key geometry objects from Watershed Workflow—such as the surface mesh and river tree—are also included to support analysis of streamflow persistency and expansion–contraction dynamics. These files can also be accessed through Watershed Workflow Python package.3) model_evaluationProvides observed streamflow time series and field survey-based flow regime classifications used to evaluate model performance. Jupyter notebooks for processing ATS outputs and comparing model predictions with observations to build confidence in the model prior to scientific analysis are also included.4) Q_L_relationshipsContains workflows for generating time series of discharge, active network length, and related hydrologic variables used in the stream network expansion–contraction analysis. Includes routines for delineating baseflow-dominated periods. For each catchment, notebooks and processed data (as pickled DataFrames accessed through Pandas Python package) are provided. 5) figure_scriptsProvides the Jupyter notebooks used to generate the figures presented in the paper.

54 ENVIRONMENTAL SCIENCES↗

Visualizing the NIOSH Pocket Guide: Open-source web application for accessing and exploring the NIOSH Pocket Guide to Chemical Hazards

The NIOSH Pocket Guide to Chemical Hazards is a trusted resource that displays key information for a collection of chemicals commonly encountered in the workplace. Entries contain chemical structures—occupational exposure limit information ranging from limits based on full-shift time-weighted averages to acute limits such as short-term exposure limits and immediately dangerous to life or health values, as well as a variety of other data such as chemical-physical properties and symptoms of exposure. The NIOSH Pocket Guide (NPG) is available as a printed, hardcopy book, a PDF version, an electronic database, and a downloadable application for mobile phones. All formats of the NIOSH Pocket Guide allow users to access the data for each chemical separately, however, the guide does not support data analytics or visualization across chemicals. This project reformatted existing data in the NPG to make it searchable and compatible with exploration and analysis using a web application. The resulting application allows users to investigate the relationships between occupational exposure limits, the range and distribution of occupational exposure limits, and the specialized sorting of chemicals by health endpoint or to summarize information of particular interest. These tasks would have previously required manual extraction of the data and analysis. The usability of this application was evaluated among industrial hygienists and researchers and while the existing application seems most relevant to researchers, the open-source code and data are amenable to modification by users to increase customization.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

RadLab: A Comprehensive Database and Analysis Toolkit for Space Radiation Measurements Relevant to Space Radiation Biology

RadLab, a new addition to the NASA Open Science Data Repository (OSDR), is a public platform for space radiation data relevant to human space exploration. RadLab consists of a database, a submission portal, and user-friendly visualization and data analysis tools, including a graphical user interface (GUI) and an application programming interface (API). Investigators from ISS partners including Germany, Italy, Canada, Hungary, the Czech Republic, Russia, Japan have committed to providing data from their instruments. RadLab will also include data from other spacecraft in LEO: the Space Shuttle, the Mir space station, biosatellites; and beyond LEO: the lunar and the Martian surface, the heliocentric orbit at 1 AU, Mars orbit, and Earth-Mars space. Once fully operational, RadLab will provide open, centralized access to space radiation physics data relevant to human space exploration; a platform for submission of data by agencies and research institutions responsible for radiation detectors deployed in space; analysis tools to facilitate detector and dataset intercomparison to better understand space habitat radiation environments; capabilities for space biology investigators to determine the radiation environment to which samples were exposed. A RadLab Working Group (RLWG) has been formed, modeled on the GeneLab Analysis Working Groups and comprised of data contributors and users. RLWG tasks include identifying data sources, normalizing data from diverse detectors, expanding the analysis toolkit and, perhaps most importantly, sharing ideas for research exploiting capabilities of RadLab. We will provide an overview of RadLab data and capabilities and discuss examples of its potential as a resource for open science.

radiation↗