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At least 361 records · Page 20

Evaluation of the Spaceflight Cardiovascular Disease Risk using the Clinical Prediction Model Astro-Charm and the NASA Radiation Risk Model

Exposure to space radiation and other spaceflight hazards may pose an increased risk for cardiovascular diseases (CVD) during and after spaceflight [1], that should be quantified to plan future long-duration space missions such as the flight to Mars. The first CVD clinical prediction models (CPMs) for individuals were developed by the Framingham Heart Study investigators in the 1960’s. Since then, many CPMs have been developed and refined. The CPMs consider cardiovascular risk factors such as blood pressure, diabetes, cholesterol, and smoking. As there is a relationship between radiation-induced CVD risk and the background (non-exposed) CVD risk, it is possible to use CPMs to calculate a personalized risk for astronauts.

I. Plante↗

Fade Dynamics and Its Evolution: The Other Part of the Acts Rain Prediction Model

The inception of the Advanced Communication Technology Satellite (ACTS) Project has required as similarly advanced statistical mathematical modeling formalism to describe the behavior of the 30/20 GHz links emanating to and from the earth terminals through the deleterious effects of the earth's atmosphere. The resulting ACTS Rain Attenuation Prediction Model has been thoroughly described in [Manning, 1990]. In the present paper, the basic rudiments of this model will be reviewed; Section 1 covers the static or time-independent portion of the model and Section 2 covers the dynamic of time-dependent portion. The results of Section 2 are then applied to a new approximate solution of the famous problem of the time duration tau of a fade of random process below some threshold. This is known as the fade duration. The new approximate solution was published in Russian [Denisenko] and, unfortunately, was never published into English. Hence, this work is restated following [Denisenko] in Section 3 which is immediately applied to the random rain fade process. The results for all five ACTS propagation sites as well as Tampa, FL are then given.

Manning, Robert M.↗

Fade Dynamics and its Evolution: The Other Part of the ACTS Rain Prediction Model

The inception of the Advanced Communication Technology Satellite (ACTS) Project has required a similarly advanced statistical mathematical modeling formalism to describe the behavior of the 30/20 GHz links emanating to and from the earth terminals through the deleterious effects of the earth's atmosphere. The resulting ACTS Rain Attenuation Prediction Model has been thoroughly described in (Manning). In the present paper, the basic rudiments of this model will be reviewed; Section 1 covers the static or time-independent portion of the model and Section 2 covers the dynamic or time-dependent portion. The results of Section 2 are then applied to a new approximate solution of the famous problem of the time duration tau of a fade of a random process below some threshold. This is known as the fade duration. The new approximate solution was published in Russian (Denisenko) and, unfortunately, was never published into English. Hence, this work is restated following (Denisenko) in Section 3 which is immediately applied to the random rain fade process. The results for all five ACTS propagation sites as well as Tampa, FL are then given.

Manning, Robert M.↗

Model Predictive Voltage Control of Large-Scale PV or Hybrid PV-BESS Plants

Increased penetration level of inverter-based resources (IBRs) and renewable energy in the power grid has called for more requirements from the control of IBRs. In this paper, the voltage-reactive power control of a photovoltaic (PV) power plant or hybrid PV-battery energy storage system (BESS) plant connected to a bulk power grid, whilst meeting the grid requirements, is studied. In this paper, a continuous-set model predictive control (MPC) formulation is proposed for voltage-reactive power control. For the same, an aggregated dynamic PV plant model is developed based on the recursive system equivalencing method. The formulation is then implemented in PSCAD simulation on a 125 MW PV plant or hybrid PV-BESS plant. The MPC implementation achieves 10.13% voltage improvement based on PSCAD simulation results in a balanced fault case study. Simulation results further demonstrate that MPC provides improved voltage support over the conventional proportional-integral (PI) controller post-fault occurrence.

Abu rub, Omar↗

Results from baseline tests of the SPRE 1 and comparison with code model predictions

The space power research engine (SPRE), a free piston Stirling engine with linear alternator, is being tested at NASA-Lewis as a candidate for high capacity space power. Results are presented of baseline engine tests at design and off-design operating conditions. The test results are compared with code model prediction.

Cairelli, James E.↗

Results from baseline tests of the SPRE I and comparison with code model predictions

The space power research engine (SPRE), a free-piston Stirling engine with linear alternator, is being tested at NASA-Lewis as a candidate for high capacity space power. Results are presented of baseline engine tests at design and off-design operating conditions. The test results are compared with code model prediction.

Cairelli, James E.↗

Comparison of Optimal Energy Management Strategies Using Dynamic Programming, Model Predictive Control, and Constant Velocity Prediction

Due to the recent advancements in autonomous vehicle technology, future vehicle velocity predictions are becoming more robust which allows fuel economy (FE) improvements in hybrid electric vehicles through optimal energy management strategies (EMS). A realworld highway drive cycle (DC) and a controls-oriented 2017 Toyota Prius Prime model are used to study potential FE improvements. We proposed three important metrics for comparison: (1) perfect full drive cycle prediction using dynamic programming, (2) 10-second prediction horizon model predictive control (MPC), and (3) 10-second constant velocity prediction. These different velocity predictions are put into an optimal EMS derivation algorithm to derive optimal engine torque and engine speed. The results show that the constant velocity prediction algorithm outperformed the baseline control strategy but underperformed the MPC strategy with an average 1.58% and 2.45% of FE improvement with highway and city-highway DC. Also, using a 10-second prediction window MPC strategy provided FE improvement results close to the full drive cycle prediction case. MPC has the potential to achieve 60%-65% and 70% - 80% of global FE improvement over highway and city-highway DC respectively.

Patel, Amol Arvind↗

Model-predictive optimal control of ferrofluidic microrobots in three-dimensional space

Ferrofluid microrobots have emerged as promising tools for minimally invasive medical procedures. Their unique properties to navigate complex fluids and reach otherwise inaccessible regions of the human body have enabled new applications in targeted drug delivery, tissue engineering, and diagnostics. Here, this paper proposes a model-predictive controller for the external magnetic manipulation of ferrofluid microrobots in three dimensions (3D). The internal optimization routine of the controller determines appropriate changes in the applied electromagnetic field to minimize the deviation between the actual and desired trajectories of the microrobot. A linear system governing locomotion is derived and used as the equality constraints of the optimization problems associated with the feedback index. In addition to ferrofluid droplets, the controller presented in this work may be applied to other magnetically-pulled microrobots. Several experiments are performed to validate the controller and showcase its ability to adapt to changes in system parameters such as the desired tracking trajectory and the size, orientation, deformation, and velocity of the microrobot. The accuracy of the controller is analyzed for each experiment, and the average error is found to be within 0.25 mm for small velocities. An additional experiment is performed to demonstrate significant improvement over a PID controller that is optimally tuned using Bayesian optimization. The results presented in this paper suggest that the proposed control algorithm could enable new microrobotic capabilities in minimally invasive medical procedures, lab-on-a-chip applications, and microfluidics.

60 APPLIED LIFE SCIENCES↗

Comparative Study of foF2 Measurements with IRI-2007 Model Predictions During Extended Solar Minimum

The unusually deep and extended solar minimum of cycle 2324 made it very difficult to predict the solar indices 1 or 2 years into the future. Most of the predictions were proven wrong by the actual observed indices. IRI gets its solar, magnetic, and ionospheric indices from an indices file that is updated twice a year. In recent years, due to the unusual solar minimum, predictions had to be corrected downward with every new indices update. In this paper we analyse how much the uncertainties in the predictability of solar activity indices affect the IRI outcome and how the IRI values calculated with predicted and observed indices compared to the actual measurements.Monthly median values of F2 layer critical frequency (foF2) derived from the ionosonde measurements at the mid-latitude ionospheric station Juliusruh were compared with the International Reference Ionosphere (IRI-2007) model predictions. The analysis found that IRIprovides reliable results that compare well with actual measurements, when the definite (observed and adjusted) indices of solar activityare used, while IRI values based on earlier predictions of these indices noticeably overestimated the measurements during the solar minimum.One of the principal objectives of this paper is to direct attention of IRI users to update their solar activity indices files regularly.Use of an older index file can lead to serious IRI overestimations of F-region electron density during the recent extended solar minimum.

Ionosphere↗

Comparison of Optimal Energy Management Strategies Using Dynamic Programming, Model Predictive Control, and Constant Velocity Prediction

Due to the recent advancements in autonomous vehicle technology, future vehicle velocity predictions are becoming more robust which allows fuel economy (FE) improvements in hybrid electric vehicles through optimal energy management strategies (EMS). A real- world highway drive cycle (DC) and a controls-oriented 2017 Toyota Prius Prime model are used to study potential FE improvements. We proposed three important metrics for comparison: (1) perfect full drive cycle prediction using dynamic programming, (2) 10-second prediction horizon model predictive control (MPC), and (3) 10-second constant velocity prediction. These different velocity predictions are put into an optimal EMS derivation algorithm to derive optimal engine torque and engine speed. The results show that the constant velocity prediction algorithm outperformed the baseline control strategy but underperformed the MPC strategy with an average 1.58% and 2.45% of FE improvement with highway and city-highway DC. Also, using a 10-second prediction window MPC strategy provided FE improvement results close to the full drive cycle prediction case. MPC has the potential to achieve 60%-65% and 70% - 80% of global FE improvement over highway and city-highway DC respectively.

Patel, Amol Arvind↗

Model predicts rain attenuation in satellite links

A model is developed which is capable of predicting the performance of satellite communication systems without complicated mathematics and case-specific physical assumptions while still embodying a general understanding of the structure and properties of rain. The Simple Attenuation Model (SAM) allows the prediction of earth-space rain attenuation at any location in the world for any elevation angle above a few degrees from 10 to 35 GHz. Comparisons of SAM predictions and measured data are presented for selected sites.

Stutzman, Warren L.↗

Identification of blood protein biomarkers associated with prostate cancer risk using genetic prediction models: analysis of over 140,000 subjects

Prostate cancer (PCa) brings huge public health burden in men. A growing number of conventional observational studies report associations of multiple circulating proteins with PCa risk. However, the existing findings may be subject to incoherent biases of conventional epidemiologic studies. To better characterize their associations, herein, we evaluated associations of genetically predicted concentrations of plasma proteins with PCa risk. In this study, we developed comprehensive genetic prediction models for protein levels in plasma. After testing 1308 proteins in 79 194 cases and 61 112 controls of European ancestry included in the consortia of BPC3, CAPS, CRUK, PEGASUS, and PRACTICAL, 24 proteins showed significant associations with PCa risk, including 16 previously reported proteins and eight novel proteins. Of them, 14 proteins showed negative associations and 10 showed positive associations with PCa risk. For 18 of the identified proteins, potential functional somatic changes of encoding genes were detected in PCa patients in The Cancer Genome Atlas (TCGA). Genes encoding these proteins were significantly involved in cancer-related pathways. We further identified drugs targeting the identified proteins, which may serve as candidates for drug repurposing for treating PCa. In conclusion, this study identifies novel protein biomarker candidates for PCa risk, which may provide new perspectives on the etiology of PCa and improve its therapeutic strategies.

59 BASIC BIOLOGICAL SCIENCES↗

A deep learning hybrid predictive modeling (HPM) approach for estimating evapotranspiration and ecosystem respiration

Climate change is reshaping vulnerable ecosystems, leading to uncertain effects on ecosystem dynamics, including evapotranspiration (ET) and ecosystem respiration (R eco ). However, accurate estimation of ET and R eco still remains challenging at sparsely monitored watersheds, where data and field instrumentation are limited. In this study, we developed a hybrid predictive modeling approach (HPM) that integrates eddy covariance measurements, physically based model simulation results, meteorological forcings, and remote-sensing datasets to estimate ET and R eco in high space–time resolution. HPM relies on a deep learning algorithm and long short-term memory (LSTM) and requires only air temperature, precipitation, radiation, normalized difference vegetation index (NDVI), and soil temperature (when available) as input variables. We tested and validated HPM estimation results in different climate regions and developed four use cases to demonstrate the applicability and variability of HPM at various FLUXNET sites and Rocky Mountain SNOTEL sites in Western North America. To test the limitations and performance of the HPM approach in mountainous watersheds, an expanded use case focused on the East River Watershed, Colorado, USA. The results indicate HPM is capable of identifying complicated interactions among meteorological forcings, ET, and R eco variables, as well as providing reliable estimation of ET and R eco across relevant spatiotemporal scales, even in challenging mountainous systems. The study documents that HPM increases our capability to estimate ET and R eco and enhances process understanding at sparsely monitored watersheds.

54 ENVIRONMENTAL SCIENCES↗

Stall Recovery Guidance Using Fast Model Predictive Control

Based on a detailed analysis of recent loss-of-control events, the Aircraft State Awareness Joint Safety Analysis Team has identified the need to develop algorithms and display strategies to provide control guidance for recovery from approach-to-stall or stall. In order to be effective, such guidance should enhance the pilots ability to execute the Federal Aviation Administrations recommended stall recovery procedure. This paper explores the use of a fast model predictive control algorithm that determines near optimal recovery guidance, which quantifies the aircraft configuration and situation dependent recovery information required to maximize the effectiveness of the recovery. This information includes the magnitude of the initial pitch down maneuver, the specific amount of airspeed and thrust needed before pulling out of the recovery dive, as well as the maximum pitch-up rate that can be sustained without causing a secondary stall. The algorithm was integrated and tested with an in-house desktop simulator that implements the General Transport Aircraft model and the associated stall aircraft dynamics. Preliminary results are presented to demonstrate the use of the proposed approach as a recovery aid for pilots.

predictive control↗

Predictive model using artificial neural network to design phase change material-based ocean thermal energy harvesting systems for powering uncrewed underwater vehicles

Uncrewed Underwater Vehicles (UUVs) are a major beneficiary of the phase change material (PCM)-based ocean thermal energy harvesting technology for their mission needs. However, this technology relies on different parameters and energy conversion steps that could be critical to the general energy generation efficiency. Sea trials showed that the design performed lower than their laboratory design specifications. This underperformance results from different factors, mainly the UUV’s trajectory, travel time, underwater ocean currents, temperature fluctuations, and biofouling on the heat exchanger due to long term underwater operations. Therefore, there exists a need to continuously monitor the ambient energy harvesting system and predict system performance, for mission planning purposes. Two major parameters influencing the energy harvesting system include the final pressure inside the hydraulic energy storage vessel or accumulator, and the electrical load value. Here, this work focuses on the hydraulic to electric energy conversion system. Therefore, a combination of numerical model and experimental testing is used to develop a predictive model using artificial neural network using MATLAB. After validation with experimental testing, 1000 data samples obtained from the numerical model are used to train the ANN. Compared to the experimental results, the developed ANN model can predict in less than a second the designed benchtop system’s total efficiency with less than 15 percent maximum error range. This predictive model development represents a cost-effective way for optimization and a computational energy efficient mode aboard UUVs for mission planning for deployed UUVs using PCM-based ocean thermal energy harvesting technology.

30 DIRECT ENERGY CONVERSION↗

Encrypted model predictive control design for security to cyberattacks

Abstract In recent years, cyber‐security of networked control systems has become crucial, as these systems are vulnerable to targeted cyberattacks that compromise the stability, integrity, and safety of these systems. In this work, secure and private communication links are established between sensor–controller and controller–actuator elements using semi‐homomorphic encryption to ensure cyber‐security in model predictive control (MPC) of nonlinear systems. Specifically, Paillier cryptosystem is implemented for encryption‐decryption operations in the communication links. Cryptosystems, in general, work on a subset of integers. As a direct consequence of this nature of encryption algorithms, quantization errors arise in the closed‐loop MPC of nonlinear systems. Thus, the closed‐loop encrypted MPC is designed with a certain degree of robustness to the quantization errors. Furthermore, the trade‐off between the accuracy of the encrypted MPC and the computational cost is discussed. Finally, two chemical process examples are employed to demonstrate the implementation of the proposed encrypted MPC design.

Suryavanshi, Atharva↗

A Coupled Probabilistic Wake Vortex and Aircraft Response Prediction Model

Wake vortex spacing standards along with weather and runway occupancy time, restrict terminal area throughput and impose major constraints on the overall capacity and efficiency of the National Airspace System (NAS). For more than two decades, the National Aeronautics and Space Administration (NASA) has been conducting research on characterizing wake vortex behavior in order to develop fast-time wake transport and decay prediction models. It is expected that the models can be used in the systems level design of advanced air traffic management (ATM) concepts that safely increase the capacity of the NAS. It is also envisioned that at a later stage of maturity, these models could potentially be used operationally, in groundbased spacing and scheduling systems as well as on the flight deck.

Gloudemans, Thijs↗