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At least 361 records · Page 20

Alternative Datasets for Identification of Earth Science Events and Data

Alternative, or non-traditional, data sources can be used to generate datasets which can in turn be analyzed for temporal, spatial and climatological patterns. Events and case studies inferred from the analysis of these patterns can be used by the remote sensing community to more effectively search for Earth observation data. In this paper, we present a new alternative Earth science dataset created from the National Weather Service’s Area Forecast Discussion (AFD) documents. We then present an exploratory methodology for identifying interesting climatological patterns within the AFD data and a corresponding motivating example as to how these data and patterns can be used to search for relevant events or case studies.

Bugbee, Kaylin↗

A Phase 1/2 and Biomarker Study of Preoperative Short Course Chemoradiation With Proton Beam Therapy and Capecitabine Followed By Early Surgery for Resectable Pancreatic Ductal Adenocarcinoma

Purpose: To evaluate the safety, efficacy and biomarkers of short-course proton beam radiation and capecitabine, followed by pancreaticoduodenectomy in a phase 1/2 study in pancreatic ductal adenocarcinoma (PDAC) patients. Methods and Materials: Patients with radiographically resectable, biopsy-proven PDAC were treated with neoadjuvant short-course (2-week) proton-based radiation with capecitabine, followed by surgery and adjuvant gemcitabine. The primary objective was to demonstrate a rate of toxicity grade ≥3 of <20%. Exploratory biomarker studies were performed using surgical specimen tissues and peripheral blood. Results: The phase 2 dose was established at 5 daily doses of 5 GyE. Fifty patients were enrolled, of whom 35 patients were treated in the phase 2 portion. There were no grade 4 or 5 toxicities, and only 2 of 35 patients (4.1%) experienced a grade 3 toxicity event (chest wall pain grade 1, colitis grade 1). Of 48 patients eligible for analysis, 37 underwent pancreaticoduodenectomy. Thirty of 37 (81%) had positive nodes. Locoregional failure occurred in 6 of 37 resected patients (16.2%), and distant recurrence occurred in 35 of 48 patients (72.9%). With median follow-up of 38 months, the median progression-free survival for the entire group was 10 months, and overall survival was 17 months. Biomarker studies showed significant associations between worse survival outcomes and the KRAS point mutation change from glycine to aspartic acid at position 12, stromal CXCR7 expression, and circulating biomarkers CEA, CA19-9, and HGF (all, P<.05). Conclusions: This study met the primary endpoint by showing a rate of 4.1% grade 3 toxicity for neoadjuvant short-course proton-based chemoradiation. Treatment was associated with favorable local control. In exploratory analyses, KRAS{sup G12D} status and high CXCR7 expression and circulating CEA, CA19-9, and HGF levels were associated with poor survival.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Off-design temperature effects on nuclear fuel pins for an advanced space-power-reactor concept

An exploratory out-of-reactor investigation was made of the effects of short-time temperature excursions above the nominal operating temperature of 990 C on the compatibility of advanced nuclear space-power reactor fuel pin materials. This information is required for formulating a reliable reactor safety analysis and designing an emergency core cooling system. Simulated uranium mononitride (UN) fuel pins, clad with tungsten-lined T-111 (Ta-8W-2Hf) showed no compatibility problems after heating for 8 hours at 2400 C. At 2520 C and above, reactions occurred in 1 hour or less. Under these conditions free uranium formed, redistributed, and attacked the cladding.

Bowles, K. J.↗

Multi-modal virtual environment research at Armstrong Laboratory

One mission of the Paul M. Fitts Human Engineering Division of Armstrong Laboratory is to improve the user interface for complex systems through user-centered exploratory development and research activities. In support of this goal, many current projects attempt to advance and exploit user-interface concepts made possible by virtual reality (VR) technologies. Virtual environments may be used as a general purpose interface medium, an alternative display/control method, a data visualization and analysis tool, or a graphically based performance assessment tool. An overview is given of research projects within the division on prototype interface hardware/software development, integrated interface concept development, interface design and evaluation tool development, and user and mission performance evaluation tool development.

Eggleston, Robert G.↗

Automatic variable selection in ecological niche modeling: A case study using Cassin’s Sparrow (Peucaea cassinii)

MERRA/Max provides a feature selection approach to dimensionality reduction that enables direct use of global climate model outputs in ecological niche modeling. The system accomplishes this reduction through a Monte Carlo optimization in which many independent MaxEnt runs, operating on a species occurrence file and a small set of randomly selected variables in a large collection of variables, converge on an estimate of the top contributing predictors in the larger collection. These top predictors can be viewed as potential candidates in the variable selection step of the ecological niche modeling process. MERRA/Max’s Monte Carlo algorithm operates on files stored in the underlying filesystem, making it scalable to large data sets. Its software components can run as parallel processes in a high-performance cloud computing environment to yield near real-time performance. In tests using Cassin’s Sparrow (Peucaea cassinii) as the target species, MERRA/Max selected a set of predictors from Worldclim’s Bioclim collection of 19 environmental variables that have been shown to be important determinants of the species’ bioclimatic niche. It also selected biologically and ecologically plausible predictors from a more diverse set of 86 environmental variables derived from NASA’s Modern-Era Retrospective Analysis for Research and Applications Version 2 (MERRA-2) reanalysis, an output product of the Goddard Earth Observing System Version 5 (GEOS-5) modeling system. We believe these results point to a technological approach that could expand the use global climate model outputs in ecological niche modeling, foster exploratory experimentation with otherwise difficult-to-use climate data sets, streamline the modeling process, and, eventually, enable automated bioclimatic modeling as a practical, readily accessible, low-cost, commercial cloud service.

John L. Schnase↗

Patient-Reported Outcomes in Pediatric Cancer Registration Trials: A US Food and Drug Administration Perspective

Pediatric patient-reported outcome (PRO) data can help inform the US Food and Drug Administration’s (FDA’s) benefit-risk assessment of cancer therapeutics by quantifying symptom and functional outcomes from the patient’s perspective. This study assessed use of PROs in commercial pediatric oncology trials submitted to the FDA for regulatory review. FDA databases were searched to identify pediatric oncology product applications approved between 1997 and 2020. Sponsor-submitted documents were reviewed to determine whether PRO data were collected, which instruments were used, and the quality of collected data (ie, sample size, completion rates, and use of fit-for-purpose instruments). The role of PROs in each trial (endpoint hierarchy) was also recorded in addition to whether any PRO endpoints were included in product labeling. We reviewed 17 pediatric oncology applications, 4 of which included PRO data: denosumab, tisagenlecleucel, larotrectinib, and selumetinib. In these 4 instances, PROs served as exploratory endpoints and were not incorporated in product labeling. Trials that collected PRO data were phase II or phase I/II single-arm studies with sample sizes of 28 to 88 patients. Symptomatic adverse events (AEs) were characterized using clinician-reported Common Terminology Criteria for Adverse Events (CTCAE) without additional patient self-report. PROs were infrequently used in pediatric cancer registration trials. When PROs were used, PRO data were limited by lack of a clear research objective and corresponding prospective statistical analysis plan. Contemporary PRO symptom libraries, such as the National Cancer Institute’s Pediatric PRO-CTCAE, may provide an opportunity to better evaluate the occurrence and impact of symptomatic AEs, from the patient’s perspective, in pediatric oncology trials.

Oncology↗

An unmanned mission to Mars with sample collection and in-situ resource utilization

The design for the Mars Analysis and Return Vehicle with In-Situ Resource Utilization (MARVIN) project is outlined. The MARVIN mission is designed to collect samples of the Martian environment; to produce fuel from local Martian resources; and to use the fuel produced to return the samples to earth. It uses only existing technologies. Exploratory Technologies' mission-design efforts have focused on methods of orbit determination, sample collection, fuel production, power, communications, control, and structural design. Lambert Targeting provided Delta-V's, launch dates, and travel times. The landing site is the Tharsis Plateau, to the southeast of Olympus Mons, chosen for its substantial scientific value. Samples of soil, dust, and atmosphere are collected with lander-based collection devices: the soil sample, with a robotic arm similar to those used in the Viking missions; the atmospheric sample, from a bleed line to the compressor in the fuel-production facility; a dust sample, from the dust-collection container in the fuel-production facility; and a redundant dust sample, with a with a passive filter system, which relies upon neither a power source nor other collection methods. The sample-return capsule (SRC) houses these samples, which are triply contained to prevent contamination. Proven technology can be used to produce methane and oxygen for fuel with relative ease at the landing site: the Sabatier reactor produces methane and water by combining carbon dioxide and hydrogen (brought from earth); the Reverse Water-Gas Shift unit combines carbon dioxide and hydrogen to form carbon monoxide and water; a water-electrolysis unit splits the water into hydrogen and oxygen. The Mars-lander vehicle (MLV) transports the equipment from earth to Mars. The Mars-ascent vehicle (MAV) contains the SRC and the engine, which is the same for both the MLV and the MAV. All equipment that is unnecessary for the Mars-Earth trajectory remains on Mars. This report presents detailed sizing information, for which a spreadsheet has been developed. The trends suggest possibilities for expansion, and suggestions for future work in these areas are offered.

Source record↗

Correlation of Fos expression and circling asymmetry during gerbil vestibular compensation

Vestibular compensation is a central nervous system process resulting in recovery of functional movement and control following a unilateral vestibular lesion. Small pressure injections of phosphorothioate 20mer oligonucleotides were used to probe the role of the Fos transcription protein during vestibular compensation in the gerbil brainstem. During isoflurane gas anesthesia, antisense probes against the c-fos mRNA sequence were injected into the medial vestibular and prepositus nuclei unilaterally prior to a unilateral surgical labyrinthectomy. Anionic dyes, which did not interact with the oligonucleotides, were used to mark the injection site and help determine the extent of diffusion. The antiFos oligonucleotide injections reduced Fos expression at the injection site in neurons which normally express Fos after the lesion, and also affected circling behavior induced by hemilabyrinthectomy. With both ipsilateral and contralateral medial vestibular and prepositus nuclei injections, less ipsilateral and more contralateral circling was noted in animals injected with antiFos injections as compared to non-injected controls. The degree of change in these behaviors was dependent upon the side of the injection. Histologically, antiFos injections reduced the number of Fos immunolabeled neurons around the injection site, and increased Fos expression contralaterally. The correlation of the number of neurons with Fos expression to turning behavior was stronger for contralateral versus ipsilateral turns, and for neurons in the caudal and ipsilateral sub-regions of the medial vestibular and prepositus nuclei. The results are discussed in terms of neuronal firing activity versus translational activity based on the asymmetrical expression of the Fos inducible transcription factor in the medial vestibular and prepositus nuclei. Although ubiquitous in the brain, transcription factors like Fos can serve localized and specific roles in sensory-specific adaptive stimuli. Antisense injections can be an effective procedure for localized intervention into complex physiological functions, e.g. vestibular compensation. Copyright 1999 Elsevier Science B.V.

NASA Discipline Neuroscience↗

Protein structural changes on a CubeSat under rocket acceleration profile

Catalyzing life-sustaining reactions, proteins are composed by 20 different amino acids that fold into a compact yet flexible three-dimensional architecture, which dictates what their function(s) might be. Determining the spatial arrangement of the atoms, the protein’s 3D structure, enables key advances in fundamental and applied research. Protein crystallization is a powerful technique to achieve this. Unlike Earth’s crystallization experiments, biomolecular crystallization in space in the absence of gravitational force is actively sought to improve crystal growth techniques. However, the effects of changing gravitational vectors on a protein solution reaching supersaturation remain largely unknown. Here, we have developed a low-cost crystallization cell within a CubeSat payload module to exploit the unique experimental conditions set aboard a sounding rocket. We designed a biaxial gimbal to house the crystallization experiments and take measurements on the protein solution in-flight with a spectrophotometry system. After flight, we used X-ray diffraction analysis to determine that flown protein has a structural rearrangement marked by loss of the protein’s water and sodium in a manner that differs from crystals grown on the ground. We finally show that our gimbal payload module design is a portable experimental setup to take laboratory research investigations into exploratory space flights.

42 ENGINEERING↗

Internal Dynamics and Crustal Evolution of Mars

The objective of this work is to improve understanding of the internal structure, crustal evolution, and thermal history of Mars by combining geophysical data analysis of topography, gravity and magnetics with results from analytical and computational modeling. Accomplishments thus far in this investigation include: (1) development of a new crustal thickness model that incorporates constraints from Mars meteorites, corrections for polar cap masses and other surface loads, Pratt isostasy, and core flattening; (2) determination of a refined estimate of crustal thickness of Mars from geoid/topography ratios (GTRs); (3) derivation of a preliminary estimate of the k(sub 2) gravitational Love number and a preliminary estimate of possible dissipation within Mars consistent with this value; and (4) an integrative analysis of the sequence of evolution of early Mars. During the remainder of this investigation we will: (1) extend models of degree-1 mantle convection from 2-D to 3-D; (2) investigate potential causal relationships and effects of major impacts on mantle plume formation, with primary application to Mars; (3) develop exploratory models to assess the convective stability of various Martian core states as relevant to the history of dynamo action; and (4) develop models of long-wavelength relaxation of crustal thickness anomalies to potentially explain the degree-1 structure of the Martian crust.

Zuber, Maria↗

Spent Nuclear Fuel Exploratory Roadmaps - 20054

The U.S. Department of Energy manages nearly 2,500 metric tons of heavy metal (MTHM) of spent nuclear fuel (SNF) resulting from several decades of research, testing, and production reactors [DOE 1995]. This SNF is managed at the DOE Hanford Site in Washington State (Hanford), Idaho National Laboratory (INL), and Savannah River Site in South Carolina (SRS). From 1995 to 2004, the Department of Energy (DOE) made several key programmatic decisions, supported by appropriate documentation in accordance with the National Environmental Policy Act (NEPA) for the management of SNF [DOE 1995]. These decisions have provided an overarching framework for SNF management, as well as site-specific and SNF-related management decisions for the past two decades. In the years since these decisions were made, with the notable exception of the successful drying and packaging of the production reactor fuel at Hanford, a majority of the decisions have been largely unimplemented. Also, since these decisions were made, a number of changes that bear on considerations relative to the path forward have occurred. A SNF Exploratory Road map activity, identified reasonable alternate pathways for DoE's inventory of SNF. Three fundamental pathways were identified in this activity for the long-term management and disposition of DOE SNF: Direct Disposal Pathway, Existing Processing Pathway and Alternate Processing Pathway. Further actions would be required (e.g., evaluation of NEPA analysis, technology maturity evaluations, refinement of cost and risks, benefits and advantages relative to other alternate paths) to define and inform many key decisions that will result in the selection of the disposition pathways that are most beneficial to the US Government in dispositioning DoE's SNF inventory. DOE is currently managing all SNF safely; however, the age of DOE-owned SNF and facilities for storing and processing SNF, coupled with the uncertainty of the storage duration, necessitates decisions and actions to ensure that the infrastructure will be in place to ensure continued safe and effective long-term management and eventual disposal. The identification of reasonable alternate pathways took these considerations into account in an effort to proactively manage conditions that could challenge the safety of storing and managing DOE SNF over the time periods now contemplated and also to ensure that flexibility is preserved to ensure that the DOE SNF remains compatible with final disposition pathways when they become available. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Milestone report - M4FT-15OR03120210 - Multi-lab Analytical Plan for Analysis of Legacy 85 Kr Samples

Legacy samples composed of 85 Kr encapsulated in solid zeolite 5A material and five small metal tubes containing a mixture of the zeolite combined with a glass matrix resulting from hot isostatic pressing have been preserved. The samples were a result of krypton R&D encapsulation efforts in the late 1970s performed at the Idaho Chemical Processing Plant. These samples were shipped to Oak Ridge National Laboratory (ORNL) in mid-FY 2014. Upon receipt the outer shipping package was opened and the inner package removed and placed in a radiation hood. The individual capsules were double bagged as they were removed from the inner shipping pig and placed into individual glass sample bottles for further analysis. The five capsules were then x-ray imaged. Capsules 1 and 4 appear to contain an amorphous mass within the capsules. Capsule 2 clearly shows the saw marks on the capsule and a quantity of loose pellet or bead-like material remaining in the capsule. Capsule 3 shows similar bead-like material within the intact capsule. Capsule 5 was previously opened. The end of this capsule appears to have been cut off and there are additional saw marks on the side of the capsule. X-ray tomography allowed the capsules to be viewed along the three axes. Of most interest was determining whether there was any residual material in the closed end of Capsule 5. The images confirmed the presence of residual material within this capsule. The material appears to be compacted but still retains some of the bead-like morphology. A conference call was held on February 19, 2015, with participation from ORNL, Idaho National Laboratory, Sandia National Laboratories, and Pacific Northwest National Laboratory Sigma Team members. The nondestructive analysis (NDA) results were discussed, and a proposed path forward was formulated to advance this effort toward the original goals of understanding the effects of extended storage on the waste form and package. Based on the initial NDA and the fact that there are at least two breached samples it was proposed that exploratory tests be conducted with the breached specimens before opening the three intact capsules. Portions of these would be analyzed to determine the fraction of krypton/xenon remaining in the matrix and the amount of rubidium remaining in the matrix. The inner surface of the breached capsules would be examined for corrosion.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Mining project's economic impact on local communities, as a social determinant of health: A documentary analysis of environmental impact statements

Australian mining developments cause indirect economic impacts on nearby communities leading to poor health and wellbeing of local residents. Economic instability is a recognised social determinant of health (SDoH); however, SDoHs are rarely considered adequately in Environmental Impact Assessments (EIAs). This research aimed to determine the extent economic impacts as a SDoH are considered in three Environmental Impact Statements (EISs) of mining projects in the New South Wales, Australia. We adopted an exploratory case study design following Yin (2012). Three cases in New South Wales, Australia, were purposively sampled as being of concern to the local community who had sought legal advice about the content of the EIS (although not necessarily for health reasons). Two were open cut mines: Watermark located in the Liverpool Plains and Warkworth Continuation in the Hunter Valley Region. The third is a comparative case – the underground Mandalong Southern Extension located in Lake Macquarie. We adapted a health-focused EIA coding framework to investigate how economic indicators as SDoH were explicitly mentioned in EISs and applied this to the three cases. Economic indicators as SDoH were rarely considered. There was a greater focus on population characteristics rather than the potential economic impacts of the mining projects on the communities. Causal association of economic determinants and health outcomes were insufficiently reported compared to best practice, and health data were not used to inform assessments. Despite two EISs – Warkworth Continuation and Watermark – associating some economic indicators to health outcomes, impacts were not adequately discussed when compared to the known literature on economic impacts of mines. Our findings show that the three EISs were inadequately utilised to determine economic impacts of mining projects on the health and wellbeing of local communities. The evidence base linking economic impacts of mines to health is underdeveloped, which compromises assessing the quality of economic coverage in EISs. EIA scoping should enable sufficient inclusion of broader determinants of health using appropriate methodology, and the economic-focused content of EISs should be subject to rigorous peer-review process to fully inform government approvals for projects. Our methods lend themselves to research in other contexts to investigate the quality of EIAs.

54 ENVIRONMENTAL SCIENCES↗

Wormhole Formation in RSRM Nozzle Joint Backfill

The RSRM nozzle uses a barrier of RTV rubber upstream of the nozzle O-ring seals. Post flight inspection of the RSRM nozzle continues to reveal occurrence of "wormholes" into the RTV backfill. The term "wormholes", sometimes called "gas paths", indicates a gas flow path not caused by pre-existing voids, but by a little-understood internal failure mode of the material during motor operation. Fundamental understanding of the mechanics of the RSRM nozzle joints during motor operation, nonlinear viscoelastic characterization of the RTV backfill material, identification of the conditions that predispose the RTV to form wormholes, and screening of candidate replacement materials is being pursued by a joint effort between Thiokol Propulsion, NASA, and the Army Propulsion & Structures Directorate at Redstone Arsenal. The performance of the RTV backfill in the joint is controlled by the joint environment. Joint movement, which applies a tension and shear load on the material, coupled with the introduction of high pressure gas in combination create an environment that exceeds the capability of the material to withstand the wormhole effect. Little data exists to evaluate why the material fails under the modeled joint conditions, so an effort to characterize and evaluate the material under these conditions was undertaken. Viscoelastic property data from characterization testing will anchor structural analysis models. Data over a range of temperatures, environmental pressures, and strain rates was used to develop a nonlinear viscoelastic model to predict material performance, develop criteria for replacement materials, and quantify material properties influencing wormhole growth. Three joint simulation analogs were developed to analyze and validate joint thermal barrier (backfill) material performance. Two exploratory tests focus on detection of wormhole failure under specific motor operating conditions. A "validation" test system provides data to "validate" computer models and predictions. Finally, two candidate replacement materials are being screened and "validated" using the developed test systems.

Stevens, J.↗

L-Band Observations with the HRMS Sky Survey Prototype System

In support of the development of NASA's High Resolution Microwave Survey (HRMS) Sky Survey Operational System (SSOS), we have conducted exploratory observations at 1.4, 1.7, and 2.3 GHZ at DSS 13 (Venus Station) in Goldstone, California.

instantaneous intermediate frequency assess the im↗

System Would Acquire Core and Powder Samples of Rocks

A system for automated sampling of rocks, ice, and similar hard materials at and immediately below the surface of the ground is undergoing development. The system, denoted a sample preparation, acquisition, handling, and delivery (SPAHD) device, would be mounted on a robotic exploratory vehicle that would traverse the terrain of interest on the Earth or on a remote planet. The SPAHD device would probe the ground to obtain data for optimization of sampling, prepare the surface, acquire samples in the form(s) of cores and/or powdered cuttings, and deliver the samples to a selected location for analysis and/or storage.

Bar-Cohen, Yoseph↗

Retrospective Analysis of Inflight Exercise Loading and Physiological Outcomes

Astronauts perform exercise throughout their missions to counter the health declines that occur as a result of long-term exposure to weightlessness. Although all astronauts perform exercise during their missions, the specific prescriptions, and thus the mechanical loading, differs among individuals. For example, inflight ground reaction force data indicate that subject-specific differences exist in foot forces created when exercising on the second-generation treadmill (T2) [1]. The current exercise devices allow astronauts to complete prescriptions at higher intensities, resulting in greater benefits with increased efficiency. Although physiological outcomes have improved, the specific factors related to the increased benefits are unknown. In-flight exercise hardware collect data that allows for exploratory analyses to determine if specific performance factors relate to physiological outcomes. These analyses are vital for understanding which components of exercise are most critical for optimal human health and performance. The relationship between exercise performance variables and physiological changes during flight has yet to be fully investigated. Identifying the critical performance variables that relate to improved physiological outcomes is vital for creating current and future exercise prescriptions to optimize astronaut health. The specific aims of this project are: 1) To quantify the exercise-related mechanical loading experienced by crewmembers on T2 and ARED during their mission on ISS; 2) To explore relationships between exercise loading variables, bone, and muscle health changes during the mission; 3) To determine if specific mechanical loading variables are more critical than others in protecting physiology; 4) To develop methodology for operational use in monitoring accumulated training loads during crew exercise programs. This retrospective analysis, which is currently in progress, is being conducted using data from astronauts that have flown long-duration missions onboard the ISS and have had access to exercise on the T2 and the Advanced Resistive Exercise Device (ARED). The specific exercise prescriptions vary for each astronaut. General exercise summary metrics will be developed to quantify exercise intensities, volumes, and durations for each subject. Where available, ground reaction force data will be used to quantify mechanical loading experienced by each astronaut. These inflight exercise metrics will be investigated relative to changes in pre- to post-flight bone and muscle health to identify which specific variables are related with improved or degraded physiological outcomes. The information generated from this analysis will fill gaps related to typical bone loading characterization, exercise performance capability, exercise volume and efficiency, and importance of exercise hardware. In addition, methods for quantification of exercise loading for use in monitoring the exercise programs during future space missions will be explored with the intent to inform exercise scientists and trainers as to the critical aspects of inflight exercise prescriptions.

Ploutz-Snyder, L. L.↗

Ice Nucleating Particle Sources at Oliktok Point Field Campaign Report

The Ice Nucleating Particle Sources at Oliktok Point U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) facility field campaign focused on chemically characterizing springtime aerosol sources at Oliktok Point, Alaska. This work was completed to improve our understanding of air masses influencing the site and altering ice nucleating particle (INP) concentrations measured by Dr. Jessie Creamean of the National Oceanic and Atmospheric Administration (NOAA) during her coordinated, simultaneous ARM field campaign “Exploratory Ice Nucleation Measurements at Oliktok”. Together these ARM field campaigns comprised INPOP (Ice Nucleating Particles at Oliktok Point). The field campaign took place at the Oliktok Point Third ARM Mobile Facility (AMF3) site from March 1 to May 31, 2017. A Davis rotating uniform motion (DRUM) impactor was deployed to collect particles for offline analysis for single-particle chemical characterization (aerosol mixing state). Barring a few interruptions due to power outages at the site, daily samples (24-h duration) were collected for analysis by computer-controlled scanning electron microscopy with energy dispersive X-ray spectroscopy (CCSEM-EDX). Unfortunately our user facility grant at the Pacific Northwest National Laboratory (PNNL) Environmental Molecular Sciences Laboratory (EMSL) was placed on hold from October 2017 to February 2018, limiting our ability to do CCSEM-EDX, as our access is also limited at the Michigan Center for Materials Characterization. Therefore, only a subset of these samples were chosen in consultation with J. Creamean and analyzed by CCSEM-EDX. We have proposed to analyze additional samples, targeting samples collected during marine air masses, as part of our DOE Atmospheric System Research (ASR) proposal “Investigating marine and terrestrial aerosol processes and cloud ice nucleation during the Alaskan Arctic melt season”. The size-resolved aerosol mixing state data produced from the ARM field campaign represent the first of such observations in the springtime at Oliktok Point. Since this AMF3 site is located within the North Slope of Alaska (NSA) oil fields near Prudhoe Bay, the site is continually influenced by combustion emissions, with natural sources also contributing to the background aerosol population.

North Slope of Alaska, Oliktok Point, aerosols, or↗