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At least 361 records · Page 20

Biostack experiment

The Apollo 17 biostack experiment to establish the biological efficiency of individual heavy nuclei particles of galactic cosmic radiation are reported. The experiment theory, interaction of heavy nuclei particles with biologic matter, and the total dose of cosmic ionizing radiation are discussed along with the radiation effects of heavy nuclei on Artemia salina eggs, and Bacillus subtilis.

H Buecker↗

Neurobehavioral Effects Of Five-Ion GCRSim Exposure In Male And Female Mice

Exposure to space galactic cosmic radiation is a principal consideration of spaceflight missions, and with upcoming missions to the Moon and Mars, it is increasingly imperative to elucidate the detrimental effects of space travel beyond the lower Earth orbit. Additionally, with the first female astronaut to soon travel to the Moon and beyond lower Earth orbit, there is a strong need to understand the biological sex differences to adaptation to the deep space environment. While the effects of spaceflight on the nervous system are not fully known, studies in animal models have shown that exposure to ionizing radiation can cause neuronal damage and lead to downstream cognitive and behavioral deficits. Therefore, we investigated the neurobehavioral responses to space environment-like radiation exposure. Male and female 23–24-week-old mice (age-matched to average astronaut age) were exposed to 5, 15 and 50 cGy via Five-Ion Galactic Cosmic Ray Simulation at the NASA National Space Radiation Laboratory at Brookhaven National Laboratory. Both early (72hrs post exposure) and late (1-4 months post exposure) cognitive and behavioral deficits were investigated. In-cage behavior was analyzed as frequency/duration of digging, rearing, and grooming and nestlet building using a 5-stage Deacon score. Additionally, at NASA Ames, behavior tests included Catwalk (gait), Zero Maze (anxiety), Adhesive Removal (sensory motor), Novel Object Recognition and Barnes Maze (working memory). There were pronounced sex differences in both early and late time points. Females typically performed the tests better than males, specifically in nestlet building, gait and working memory, though males performed better at the sensory motor (adhesive removal) test. Dose effects were primarily observed at 50 cGy for both sexes, particularly with the Barnes Maze (working memory), where both males and females exposed to 50 cGy showed little to no improvement in test performance, though females again performed better than males. Currently, we are investigating the correlations between the observed behavior and cytokine levels in the plasma and brain. Future studies will continue to investigate cognitive consequences of galactic cosmic radiation in combination with other space-like environment stressors, including antigravity and social versus single housing.

Stephanie Puukila↗

Neurobehavioral Effects Of Five-Ion GCRSim Exposure In Male And Female Mice

Exposure to space galactic cosmic radiation is a principal consideration of spaceflight missions, and with upcoming missions to the Moon and Mars, it is increasingly imperative to elucidate the detrimental effects of space travel beyond the lower Earth orbit. Additionally, with the first female astronaut to soon travel to the Moon and beyond lower Earth orbit, there is a strong need to understand the biological sex differences to adaptation to the deep space environment. While the effects of spaceflight on the nervous system are not fully known, studies in animal models have shown that exposure to ionizing radiation can cause neuronal damage and lead to downstream cognitive and behavioral deficits. Therefore, we investigated the neurobehavioral responses to space environment-like radiation exposure. Male and female 23–24-week-old mice (age-matched to average astronaut age) were exposed to 5, 15 and 50 cGy via Five-Ion Galactic Cosmic Ray Simulation at the NASA National Space Radiation Laboratory at Brookhaven National Laboratory. Both early (72hrs post exposure) and late (1-4 months post exposure) cognitive and behavioral deficits were investigated. In-cage behavior was analyzed as frequency/duration of digging, rearing, and grooming and nestlet building using a 5-stage Deacon score. Additionally, at NASA Ames, behavior tests included Catwalk (gait), Zero Maze (anxiety), Adhesive Removal (sensory motor), Novel Object Recognition and Barnes Maze (working memory). There were pronounced sex differences in both early and late time points. Females typically performed the tests better than males, specifically in nestlet building, gait and working memory, though males performed better at the sensory motor (adhesive removal) test. Dose effects were primarily observed at 50 cGy for both sexes, particularly with the Barnes Maze (working memory), where both males and females exposed to 50 cGy showed little to no improvement in test performance, though females again performed better than males. Currently, we are investigating the correlations between the observed behavior and cytokine levels in the plasma and brain. Future studies will continue to investigate cognitive consequences of galactic cosmic radiation in combination with other space-like environment stressors, including antigravity and social versus single housing.

S. Puukila↗

Early And Late Neurobehavioral Effects Of Male And Female Mice Exposed To Five-Ion GCRSim

With upcoming missions to the Moon and beyond to Mars, it is increasingly imperative to elucidate the detrimental effects of space travel beyond the lower Earth orbit, particularly to galactic cosmic radiation. Additionally, with the first female astronaut to soon travel to the Moon there is a strong need to understand the biological sex differences to adaptation to the deep space environment. While the effects of spaceflight on the nervous system are not fully known, studies in animal models have shown that exposure to ionizing radiation can cause neuronal damage and lead to downstream cognitive and behavioral deficits. Here, we investigated the neurobehavioral responses to space environment-like radiation exposure. Male and female 23–24-week-old mice (age-matched to average astronaut age) were exposed to 5, 15 and 50 cGy via Five-Ion Galactic Cosmic Ray Simulation at the NASA National Space Radiation Laboratory at Brookhaven National Laboratory. Both early (72hrs post exposure) and late (1-4 months post exposure) cognitive and behavioral deficits were investigated. Early analysis was performed by observing in-cage behavior including frequency/duration of digging, rearing, and grooming and nestlet building. Additionally, late effects were analyzed at NASA Ames via in-cage behavior as well as Catwalk (gait), Zero Maze (anxiety), Adhesive Removal (sensory motor), Novel Object Recognition and Barnes Maze (working memory). There were pronounced sex differences in both early and late time points. Females scored better than males in nestlet building, gait and working memory while males scored better at the sensory motor (adhesive removal) test. Dose effects were primarily observed at 50 cGy for both sexes, particularly with the Barnes Maze (working memory), where both males and females exposed to 50 cGy showed little to no improvement in test performance, though females again performed better than males. Currently, we are investigating the correlations between the observed behavior and cytokine levels in the plasma and brain. Future studies will continue to investigate cognitive consequences of galactic cosmic radiation in combination with other space-like environment stressors, including antigravity and social versus single housing.

S Puukila↗

Ultra Low Level Environmental Neutron Measurements Using Superheated Droplet Detectors

Through the application of superheated droplet detectors (SDDs), the SIMPLE project for the direct search for dark matter (DM) reached the most restrictive limits on the spin-dependent sector to date. The experiment is based on the detection of recoils following WIMP-nuclei interaction, mimicking those from neutron scattering. The thermodynamic operation conditions yield the SDDs intrinsically insensitive to radiations with linear energy transfer below ∼150 keVμm{sup -1} such as photons, electrons, muons and neutrons with energies below ∼40 keV. Underground facilities are increasingly employed for measurements in a low-level radiation background (DM search, gamma-spectroscopy, intrinsic soft-error rate measurements, etc.), where the rock overburden shields against cosmic radiation. In this environment the SDDs are sensitive only to α-particles and neutrons naturally emitted from the surrounding materials. Recently developed signal analysis techniques allow discrimination between neutron and α-induced signals. SDDs are therefore a promising instrument for low-level neutron and α measurements, namely environmental neutron measurements and α-contamination assays. In this work neutron measurements performed in the challenging conditions of the latest SIMPLE experiment (1500 mwe depth with 50-75 cm water shield) are reported. The results are compared with those obtained by detailed Monte Carlo simulations of the neutron background induced by {sup 238}U and {sup 232}Th traces in the facility, shielding and detector materials. Calculations of the neutron energy distribution yield the following neutron fluence rates (in 10{sup -8} cm{sup -2}s{sup -1}): thermal (<0.5 eV): 2.5; epithermal (0.5 eV-100 keV): 2.2; fast (>1 MeV): 3.9. Signal rates were derived using standard cross sections and codes routinely employed in reactor dosimetry. The measured and calculated neutron count rates per unit of active mass were 0.15 ct/kgd and 0.33 ct/kg-d respectively. As the major signal contribution (98%) originates from radio-impurities in the detector container, alternative materials will be employed in future devices. Latest results regarding the improvement of the detector characterization accuracy towards its application in environmental neutron detection are in progress and will be described. (authors)

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

The Projection of Space Radiation Environments with a Solar Cycle Statistical Model

A solar cycle statistical model has been developed to project sunspot numbers which represent the variations in the space radiation environment. The resultant projection of sunspot numbers in near future were coupled to space-related quantities of interest in radiation protection, such as the galactic cosmic radiation (GCR) deceleration potential (f) and the mean occurrence frequency of solar particle event (SPE). Future GCR fluxes have been derived from a predictive model, in which GCR temporal dependence represented by f was derived from GCR flux and ground-based Climax neutron monitor rate measurements over the last four decades. Results showed that the point dose equivalent inside a typical spacecraft in interplanetary radiation fields was influenced by solar modulation up to a factor of three. One important characteristic of sporadic SPEs is their mean frequency of occurrence, which is dependent on solar activity. Projections of future mean frequency of SPE occurrence were estimated from a power law function of sunspot number. Furthermore, the cumulative probabilities of SPE during short-period missions were defined with the continuous database of proton fluences of SPE. The analytic representation of energy spectra of SPE was constructed by the Weibull distribution for different event sizes. The representative exposure level at each event size was estimated for the guideline of protection systems for astronauts during future space exploration missions.

Kim, Myung-Hee↗

MCNP6 Elevation Scaling of Cosmic Ray Backgrounds - Paper 29

The galactic cosmic-ray (GCR) source option was implemented in the all-energy, all-particle transport code MCNP62 in 2010. This source option along with other newly added features to MCNP6 have been used to produce increasingly accurate global cosmic and terrestrial background flux data files (background.dat).3 This data file is produced on a grid and is read and sampled by MCNP6 whenever a user invokes the background source option. The most recent adaptation of this data file, Version 4, will be completed in 2014. This paper reports on current progress toward enhancements that have been made to the modeling and simulation of these background spectra, in particular the elevation scaling used to produce more accurate spectra at off-grid locations. Cosmic radiation continuously bombards Earth with various particles, such as protons, alpha particles, and heavier nuclei, some of which are deflected by the Earth's shielding magnetic field. Particles that carry sufficient momentum can overcome the deflection and penetrate into the atmosphere. The sufficient momentum is dependent on the terrestrial coordinates due to the shape of the Earth's magnetic field and the Lorentz force's proportionality to the sine of the angle between the velocity vector of the incoming particle and the magnetic field direction. As the particles propagate through the atmosphere, collisions with atmospheric molecules generate secondary particles such as neutrons, protons, photons, muons, pions, and other exotic particles. These secondary particles often have sufficient energy to undergo additional nuclear interactions, and so on, forming what is known as a cascade shower. The particles in the cascade shower are constantly undergoing energy losses due to interactions, especially charged particles whose paths are bent into helical trajectories around magnetic field lines. These energy losses make the integral flux of the cosmic background at the ground level highly dependent on the atmospheric depth traveled by the incident particle and its progeny, and therefore dependent on the elevation of the ground where the cascade deposits its energy. For relatively small depth changes of approximately 100 g/cm{sup 2} or less, the ground-level cosmic flux follows an exponential model. The tabulation of background particle fluxes on the surface of the earth is important for a variety of reasons, one of which is the design of nuclear material detection systems. This method is also useful in producing user-specified effective attenuation lengths for particles. Attenuation lengths are an essential parameter used to compare particle spectra from different locations, elevations, and energy ranges. Traditionally these attenuation lengths are inferred from measured data. Now with the ability to simulate an accurate galactic cosmic ray source and transport it and its shower through a modeled atmosphere, these attenuation lengths can be calculated for any set of conditions. (authors)

61 RADIATION PROTECTION AND DOSIMETRY↗

{sup 14}C Entry into the Atmosphere

{sup 14}C enters the atmosphere in amounts equivalent to 1.4 PBq/yr with total accumulation 140 PBq via cosmic radiation. As a result of nuclear explosions (1950–1969), its activity in the atmosphere exceeded 200 PBq. At present, {sup 14}C has been completely removed into bottom waters and sedimentary rocks in the ocean. The activity of the {sup 14}C entering the atmosphere from all operating nuclear reactors equals ~0.3 PBq/yr and the amount from all spent fuel reprocessing facilities equals ~0.06 PBq/yr. The admissible levels of {sup 14}C emissions must not exceed levels corresponding to peroral intake dose 10 μSv/yr. This is can be accomplished by means of a system of measures: reduction of the volume of technogenic gases and their {sup 12}CO{sub 2} content, combining high-efficiency purification with dispersion through high exhaust-stacks, and developing new technologies and reagents binding {sup 14}C in compact forms.

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗

Physical considerations relevant to HZE-particle transport in matter

High-energy, highly charged (HZE) heavy nuclei may seem at first sight to be an exotic type of radiation, only remotely connected with nuclear power generation. On closer examination it becomes evident that heavy-ion accelerators are being seriously considered for driving inertial confinement fusion reactors, and high-energy heavy nuclei in the cosmic radiation are likely to place significant constraints on satellite power system deployment and space-based power generation. The use of beams of heavy nuclei in an increasing number of current applications, as well as their importance for the development of the state of the art of the future, makes it necessary to develop at the same time a good understanding of their transport through matter.

NASA Program Biomedical Research↗

Effects of Nuclear Cross Sections at Different Energies on the Radiation Hazard from Galactic Cosmic Rays

The radiation hazard for astronauts from galactic cosmic rays is a major obstacle in long duration human space explorations. Space radiation transport codes have been developed to calculate radiation environment on missions to the Moon, Mars or beyond. We have studied how uncertainties in fragmentation cross sections at different energies affect the accuracy of predictions from such radiation transport. We find that, in deep space, cross sections between 0.3 and 0.85 GeV/u usually have the largest effect on dose-equivalent behind shielding in solar minimum GCR environments, and cross sections between 0.85 and 1.2 GeV/u have the largest effect in solar maximum GCR environments. At the International Space Station, cross sections at higher energies have the largest effect due to the geomagnetic cutoff.

Lin, Z. W.↗