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At least 37 records · Page 2

Anterior segment sparing to reduce charged particle radiotherapy complications in uveal melanoma

PURPOSE: The purpose of this investigation is to delineate the risk factors in the development of neovascular glaucoma (NVG) after helium-ion irradiation of uveal melanoma patients and to propose treatment technique that may reduce this risk. METHODS AND MATERIALS: 347 uveal melanoma patients were treated with helium-ions using a single-port treatment technique. Using univariate and multivariate statistics, the NVG complication rate was analyzed according to the percent of anterior chamber in the radiation field, tumor size, tumor location, sex, age, dose, and other risk factors. Several University of California San Francisco-Lawrence Berkeley National Laboratory (LBNL) patients in each size category (medium, large, and extralarge) were retrospectively replanned using two ports instead of a single port. By using appropriate polar and azimuthal gaze angles or by treating patients with two ports, the maximum dose to the anterior segment of the eye can often be reduced. Although a larger volume of anterior chamber may receive a lower dose by using two ports than a single port treatment. We hypothesize that this could reduce the level of complications that result from the irradiation of the anterior chamber of the eye. Dose-volume histograms were calculated for the lens, and compared for the single and two-port techniques. RESULTS: NVG developed in 121 (35%) patients. The risk of NVG peaked between 1 and 2.5 years posttreatment. By univariate and multivariate analysis, the percent of lens in the field was strongly correlated with the development of NVG. Other contributing factors were tumor height, history of diabetes, and vitreous hemorrhage. Dose-volume histogram analysis of single-port vs. two-port techniques demonstrate that for some patients in the medium and large category tumor groups, a significant decrease in dose to the structures in the anterior segment of the eye could have been achieved with the use of two ports. CONCLUSION: The development of NVG after helium-ion irradiation is correlated to the amount of lens, anterior chamber in the treatment field, tumor height, proximity to the fovea, history of diabetes, and the development of vitreous hemorrhage. Although the influence of the higher LET deposition of helium-ions is unclear, this study suggests that by reducing the dose to the anterior segment of the eye may reduce the NVG complications. Based on this retrospective analysis of LBNL patients, we have implemented techniques to reduce the amount of the anterior segment receiving a high dose in our new series of patients treated with protons using the cyclotron at the UC Davis Crocker Nuclear Laboratory (CNL).

NASA Discipline Radiation Health↗

The Swift GRB Mission

Swift is a MIDEX mission that is in development for launch in October 2004. It is a multiwavelength transient observatory for GRB astronomy. The goals of the mission are to determine the origin of GRBs and their afterglows and use bursts to probe the early Universe. A wide-field gamma-ray camera will detect mare than 100 GRBs per year to -3 times fainter than BATSE. Sensitive narrow-field X-ray and UV/optical telescopes will be pointed at the burst location in 20 to 75 sec by an autonomously controlled spacecraft. Far each burst, aresec positions will be determined and optical/UV/X-ray/gamma-say spectrophotometry performed. Measurements of redshift will be made for many burstes. The instrumentation is a combination of superb existing flight-spare hardware and design from XMM and Spectrum-X/JET-X contributed by collaborators in the UK and Italy and development of a coded-aperture camera with a large-area (approx. 0.5 square meter) CdZnTe detector array. Key components of the mission are vigorous follow-up and outreach programs to engage the astronomical community and public in Swift. The talk vi11 describe the mission statue and give a summary of plans for GRB operations. It is likely that Swift will have just been launched at the time of the conference.

Gehrels, Neil↗

Structure-function analysis of the FCRL5–IgG1 Fc complex reveals an unappreciated pathway for B cell modulation by Fc-attenuated IgG

The Fc region of therapeutic IgG antibodies is often engineered to remove or “silence” Fc effector functions, but it remains unclear whether these mutations eliminate all Fc-mediated effector activity. Human Fc receptor-like 5 (FCRL5/FcRH5) is a low-affinity IgG Fc receptor expressed on B cells and is an actively pursued antibody target in multiple myeloma. Here, we show that common Fc function-silencing mutations do not impair FCRL5-mediated activity and therefore attenuate, rather than eliminate, Fc effector function. The crystal structure of the FCRL5-IgG1 Fc complex, solved at 3.4 Å resolution, revealed that FCRL5 binds IgG1 Fc in a 1:1 complex through a binding mode distinct from that of classical Fcγ receptors, explaining why mutations that attenuate Fc effector function spare FCRL5 binding. Fc-engineered antibodies that selectively engage FCRL5 inhibited B cell receptor-induced Ca 2+ flux in FCRL5-expressing B cells. These findings demonstrate that Fc-attenuated therapeutic IgG retains the ability to engage FCRL5, identifying an unappreciated pathway for B cell modulation.

Herpers, Bart M. [Department of Biomedical Enginee↗

Lightning Imaging Sensor on the International Space Station: Assessments and Results from First Year Operations

Over two decades, the NASA Marshall Space Flight Center, the University of Alabama in Huntsville, and their partners have demonstrated the effectiveness and value of space-based lightning observations as a remote sensing tool for Earth science research and applications, and, in the process, established a robust global lightning climatology. The Lightning Imaging Sensor (LIS) on the Tropical Rainfall Measuring Mission (TRMM) provided global observations of tropical lightning for an impressive 17 years before that mission came to a close in April 2015. Now a space-qualified LIS, built as the flight spare for TRMM, has been installed on the International Space Station (ISS) for a minimum two year mission following its SpaceX launch on February 19, 2017. The LIS, flown as a hosted payload on the Department of Defense Space Test Program-Houston 5 (STP-H5) mission, was delivered to the ISS in the Dragon trunk and robotically installed in an Earth-viewing position on the outside of the ISS. Following successful activation and checkout, LIS has continuously observed the amount, rate, and radiant energy lightning within its field-of-view as it orbits the Earth. Placing LIS on the Space Station provides a great opportunity to not only extend the 17-year TRMM LIS record of tropical lightning measurements but also to expand that coverage to higher latitudes missed by the previous mission. Furthermore, this mission continues the important science focus to better understand the processes which cause lightning, as well as the connections between lightning and subsequent severe weather events. This understanding is a key to improving weather predictions and saving lives and property here in the United States and around the world. The LIS measurements, along with observations from the new Geostationary Lightning Mapper (GLM) operating on NOAA's newest weather satellites, the Geosynchronous Operational Environmental Satellite-16/17 (GOES-16/17), are being used to cross-validate both systems. An especially unique contribution from the ISS platform is the production of real-time lightning data, especially valuable for operational forecasting and warning applications over data sparse regions such as the oceans. Finally, LIS provides simultaneous and complementary observations with other ISS payloads such as the European Space Agency's Atmosphere-Space Interaction Monitor (ASIM) that is exploring the connection between thunderstorms and lightning with terrestrial gamma-ray flashes (TGFs). Leveraging TRMM's well-established processing and data handling assures that LIS data can be quickly delivered to users.

space-based lightning↗

The Swift Gamma Ray Burst Mission

Swift is an international mission managed by NASA as part of its MIDEX program. It is a multiwavelength transient observatory for GRB astronomy that will launch in 2004. The goals of the mission are to determine the origin of GRBs and their afterglows and use bursts to probe the early Universe. A wide field gamma-ray camera will detect more than a hundred GRBs per year to 2-5 times fainter than BATSE. Sensitive narrow-field X-ray, and UV/optical telescopes will be pointed at the burst location in 20 to 75 sec by an autonomously controlled 'swift' spacecraft. For each burst, arcsec positions will be determined and optical/UV/x-ray/gamma-ray spectrophotometry performed. Measurements of redshift will be made for many of the bursts. The instrumentation is a combination of superb existing flight-spare hardware and design from XMM and Spectrum-X/JET-X contributed by collaborators in the UK and Italy and development of a coded-aperture camera with a large-area (approx. 0.5 square meter) CdZnTe detector array. The instruments have now completed their fabrication phase and are integrated on the observatory for final testing. Key components of the mission are vigorous follow-up and outreach programs to engage the astronomical community and public in Swift. The talk will describe the mission and its status and give a summary of our plans for GRB operations.

Gehrels, Neil↗

Target Selection and Sample Characterization for the DESI LOW-Z Secondary Target Program

Abstract We introduce the DESI LOW- Z Secondary Target Survey, which combines the wide-area capabilities of the Dark Energy Spectroscopic Instrument (DESI) with an efficient, low-redshift target selection method. Our selection consists of a set of color and surface brightness cuts, combined with modern machine-learning methods, to target low-redshift dwarf galaxies ( z < 0.03) between 19 < r < 21 with high completeness. We employ a convolutional neural network (CNN) to select high-priority targets. The LOW- Z survey has already obtained over 22,000 redshifts of dwarf galaxies ( M * < 10 9 M ⊙ ), comparable to the number of dwarf galaxies discovered in the Sloan Digital Sky Survey DR8 and GAMA. As a spare fiber survey, LOW- Z currently receives fiber allocation for just ∼50% of its targets. However, we estimate that our selection is highly complete: for galaxies at z < 0.03 within our magnitude limits, we achieve better than 95% completeness with ∼1% efficiency using catalog-level photometric cuts. We also demonstrate that our CNN selections z < 0.03 galaxies from the photometric cuts subsample at least 10 times more efficiently while maintaining high completeness. The full 5 yr DESI program will expand the LOW- Z sample, densely mapping the low-redshift Universe, providing an unprecedented sample of dwarf galaxies, and providing critical information about how to pursue effective and efficient low-redshift surveys.

79 ASTRONOMY AND ASTROPHYSICS↗

Lightning Imaging Sensor (LIS) for the International Space Station (ISS): Mission Description and Science Goals

In recent years, the NASA Marshall Space Flight Center, the University of Alabama in Huntsville, and their partners have developed and demonstrated space-based lightning observations as an effective remote sensing tool for Earth science research and applications. The Lightning Imaging Sensor (LIS) on the Tropical Rainfall Measuring Mission (TRMM) continues to acquire global observations of total (i.e., intracloud and cloud-to-ground) lightning after 17 years on-orbit. However, TRMM is now low on fuel, so this mission will soon be completed. As a follow on to this mission, a space-qualified LIS built as the flight spare for TRMM has been selected for flight as a science mission on the International Space Station (ISS). The ISS LIS will be flown as a hosted payload on the Department of Defense Space Test Program (STP) H5 mission, which has a January 2016 baseline launch date aboard a SpaceX launch vehicle for a 2-4 year or longer mission. The LIS measures the amount, rate, and radiant energy of total lightning over the Earth. More specifically, it measures lightning during both day and night, with storm scale resolution (approx. 4 km), millisecond timing, and high, uniform detection efficiency, without any land-ocean bias. Lightning is a direct and most impressive response to intense atmospheric convection. It has been found that lightning measured by LIS can be quantitatively related to thunderstorm and other geophysical processes. Therefore, the ISS LIS lightning observations will continue to provide important gap-filling inputs to pressing Earth system science issues across a broad range of disciplines, including weather, climate, atmospheric chemistry, and lightning physics. A unique contribution from the ISS platform will be the availability of real-time lightning data, especially valuable for operational applications over data sparse regions such as the oceans. The ISS platform will also uniquely enable LIS to provide simultaneous and complementary observations with other ISS payloads such as the European Space Agency's Atmosphere-Space Interaction Monitor (ASIM) that will be exploring the connection between thunderstorms and lightning with terrestrial gamma-ray flashes (TGFs) and the Japan Aerospace Exploration Agency's Global LIghtning and Sprites MeasurementS (GLIMS) with its focus on global lightning and sprite connections. Another important function of the ISS LIS will be to provide cross-sensor calibration/validation with a number of other payloads, including the TRMM LIS and the next generation geostationary lightning mappers such as the GOES-R Geostationary Lightning Mapper (GLM) and Meteosat Third Generation Lightning Imager (MTG LI), as well as with ground-based lightning detection systems. These inter-calibrations will improve the long term climate monitoring record provided by all these systems. Finally, the ISS LIS will extend the time-series climate record of LIS lightning observations and expand the latitudinal coverage of LIS lightning to the climate significant upper middle-latitudes.

Blakeslee, R. J.↗

The Swift MlDEX Mission

Swift is a NASA MIDEX mission that is in development for launch in 2004. It is a multiwavelength observatory for transient astronomy. The goals of the mission are to determine the origin of gamma-ray bursts and their afterglows and use bursts to probe the early Universe. The mission will also perform a hard x-ray survey at the 1 milliCrab level and will continuously monitor the sky for transients. A wide- field gamma-ray camera will detect more than a hundred GRBs per year to 3 times fainter than BATSE. Sensitive narrow-field X-ray and Uv/optical telescopes will be pointed at the burst location in 20 to 70 sec by an autonomously controlled "swift" spacecraft. For each burst, arcsec positions will be determined and optical/W/X-ray/gamma-ray spectrophotometry performed. The instrumentation is a combination of existing flight-spare hardware and design from XMM and Spectrum-X/JET-X contributed by collaborators in the UX and Italy and development of a coded-aperture camera with a large-area (-0.5 square meter) CdZnTe detector array. The ground station in Malindi is contributed by the Italian Space Agency. The instruments have now completed their fabrication phase and are currently being integrated on the observatory for final testing. up and outreach programs to engage the astronomical community and public in Swift.

Gehrels, Neil↗

Advancements in Logistics Reduction for Exploration Missions

Management of logistics on exploration missions includes both looking for ways to minimize the quantities, mass and volume of various consumables, supplies, spares and equipment as well as ways to minimize the crew time needed for locating and handling those items. Also included are ways to minimize the waste, handling and resultant products from the processes of maintaining a crew on these missions. The Logistics Reduction project encompasses technologies for management of waste, trash, autonomous logistics, and clothing. This paper provides a status of work in these areas including recent accomplishments and challenges encountered. Future objectives will also be covered along with the work currently in progress. Specifically, the paper will cover technologies in waste management, namely, the Universal Waste Management System (UWMS) or exploration toilet and work on an alternative waste collection container, the Alternate Fecal Canister. Trash management technologies work on the Trash Compaction and Processing System (TCPS) and Trash to Gas (TtG) is summarized with progress to date as well as information on how Jettison as an option is related. Progress and summary of recent accomplishment on the RFID (Radio Frequency ID) Enabled Autonomous Logistics Management (REALM) and the Autonomous Logistics (AL) technologies is detailed. Advanced Clothing System (ACS) and work in the area of Systems Engineering and Integration (SE&I) is also included. Status of the technologies, accomplishments and how the focus areas inform program decisions will be addressed.

human spaceflight↗

Advancements in Logistics Reduction Technologies for Exploration Missions

Management of logistics on exploration missions includes both looking for ways to minimize the quantities, mass and volume of various consumables, supplies, spares and equipment as well as ways to minimize the crew time needed for locating and handling those items. Also included are ways to minimize the waste, handling and resultant products from the processes of maintaining a crew on these missions. The Logistics Reduction project encompasses technologies for management of waste, trash, autonomous logistics, and clothing. This paper provides a status of work in these areas including recent accomplishments and challenges encountered. Future objectives will also be covered along with the work currently in progress. Specifically, the paper will cover technologies in waste management, namely, the Universal Waste Management System (UWMS) or exploration toilet and work on an alternative waste collection container, the Alternate Fecal Canister. Trash management technologies work on the Trash Compaction and Processing System (TCPS) and Trash to Gas (TtG) is summarized with progress to date as well as information on how Jettison as an option is related. Progress and summary of recent accomplishment on the RFID (Radio Frequency ID) Enabled Autonomous Logistics Management (REALM) and the Autonomous Logistics (AL) technologies is detailed. Advanced Clothing System (ACS) and work in the area of Systems Engineering and Integration (SE&I) is also included. Status of the technologies, accomplishments and how the focus areas inform program decisions will be addressed.

human spaceflight↗

The Imminent Swift MIDEX Mission

Swift is a NASA MIDEX mission that is in development for launch in Fall 2004. It is a multiwavelength observatory for transient astronomy. The goals of the mission are to determine the origin of gamma-ray bursts and their afterglows and use bursts to probe the early Universe. The mission will also perform a hard x-ray survey at the 1 milliCrab level and will continuously monitor the sky for transients. A wide-field gamma-ray camera will detect more than a hundred GRBs per year to 3 times fainter than BATSE. Sensitive narrow-field X-ray and UV/optical telescopes will be pointed at the burst. location in 20 to 70 sec by an autonomously controlled "swift" spacecraft. For each burst, arcsec positions will be determined and optical/UV/X-ray/gamma-ray spectrophotometry performed. The instrumentation is a combination of existing flight-spare hardware and design from XMM and Spectrum-X/JET-X contributed by collaborators in the UK and Italy and development of a coded-aperture camera with a large-area (approximately 0.5 square meter) CdZnTe detector array. The ground station in Malindi is contributed by the Italian Space Agency. The instruments have now completed their fabrication phase and are currently being integrated on the observatory for final testing. Key components of the mission are vigorous follow-up and outreach programs to engage the astronomical community and public in Swift.

Gehrels, Neil↗

The Swift Gamna-Ray Burst Mission

Swift is a NASA Explorer mission that will be launched in late 2004. It is a multiwavelength observatory for transient astronomy. The goals of the mission are to determine the origin of gamma-ray bursts and their afterglows and use bursts to probe the early Universe. The mission will also perform a hard x-ray survey at the 1 milliCrab level and will continuously monitor the sky for transients. A wide-field gamma-ray camera will detect more than a hundred GRBs per year to 3 times fainter than BATSE. Sensitive narrow-field X-ray and UV/optical telescopes will be pointed at the burst location in 20 to 70 sec by an autonomously controlled "swift" spacecraft. For each burst, arcsec positions will be determined and optical/UV/X-ray/gamma-ray spectrophotometry performed. The instrumentation is a combination of existing flight-spare hardware and design from XMM and Spectrum-X/JET-X contributed by collaborators in the UK and Italy and development of a coded-aperture camera with a large-area (-0.5 square meter) CdZnTe detector array. The ground station in Malindi is contributed by the Italian Space Agency. Key components of the mission are vigorous follow-up and outreach programs to engage the astronomical community and public in Swift.

Gehrels, Neil↗

Advancements in Logistics Reduction Technologies for Exploration Missions

Management of logistics on exploration missions includes both looking for ways to minimize the quantities, mass and volume of various consumables, supplies, spares, and equipment as well as ways to minimize the crew time needed for locating and handling those items. Also included are ways to minimize the waste, handling and resultant products from the processes of maintaining a crew on these missions. The Logistics Reduction project within Exploration Capabilities (ExCap) encompasses technologies for management of waste, trash, autonomous logistics, and clothing. This paper provides a status of work in these areas including recent accomplishments and challenges encountered. Future objectives will also be covered along with the work currently in progress. Specifically, the paper will cover technologies in waste management, namely, the Universal Waste Management System (UWMS) which is the exploration toilet and work on an alternative waste collection container, the Alternate Fecal Canister (AFC). Trash management technologies work on the Trash Compaction and Processing System (TCPS) and Trash to Gas (TtG) is summarized with progress to date as well as information on how trash jettison as an option is related. Progress and summary of recent accomplishment on the RFID (Radio Frequency ID) Enabled Autonomous Logistics Management (REALM) and the Autonomous Logistics (AL) technologies is detailed. Advanced Clothing System (ACS) and work in Systems Engineering and Integration (SE&I) is also included. Status of the technologies, accomplishments and how the focus areas inform program decisions will be addressed.

human spaceflight↗

Advancements in Logistics Reduction Technologies for Exploration Missions

Management of logistics on exploration missions includes both looking for ways to minimize the quantities, mass and volume of various consumables, supplies, spares, and equipment as well as ways to minimize the crew time needed for locating and handling those items. Also included are ways to minimize the waste, handling and resultant products from the processes of maintaining a crew on these missions. The Logistics Reduction project within Exploration Capabilities (ExCap) encompasses technologies for management of waste, trash, autonomous logistics, and clothing. This paper provides a status of work in these areas including recent accomplishments and challenges encountered. Future objectives will also be covered along with the work currently in progress. Specifically, the paper will cover technologies in waste management, namely, the Universal Waste Management System (UWMS) which is the exploration toilet and work on an alternative waste collection container, the Alternate Fecal Canister (AFC). Trash management technologies work on the Trash Compaction and Processing System (TCPS) and Trash to Gas (TtG) is summarized with progress to date as well as information on how trash jettison as an option is related. Progress and summary of recent accomplishment on the RFID (Radio Frequency ID) Enabled Autonomous Logistics Management (REALM) and the Autonomous Logistics (AL) technologies is detailed. Advanced Clothing System (ACS) and work in Systems Engineering and Integration (SE&I) is also included. Status of the technologies, accomplishments and how the focus areas inform program decisions will be addressed.

human spaceflight↗

Swift: A Gamma Ray Bursts Explorer

Swift is a NASA gamma-ray burst MIDEX mission that is in development for launch in December 2003. It is a multiwavelength transient observatory for GRB astronomy. The goals of the mission are to determine the origin of GRBs and their afterglows and use bursts to probe the early Universe. It will also.perform a survey of the hard X-ray sky to a sensitivity level of -1 mCrab. A wide-field camera will detect more than a hundred GRBs per year to 5 times fainter than BATSE. Sensitive narrow-field X-ray and UV/optical telescopes will be pointed at the burst location in 20 to 70 sec by an autonomously controlled 'swift' spacecraft. For each burst, arcsec positions will be determined and optical/UV/X-ray/gamma-ray spectrophotometry performed. Measurements of redshift will be made for many of the bursts. The instrumentation is a combination of superb existing flight-spare hardware and design from XMM and Spectrum-X/JET-X contributed by collaborators in the UK and Italy and development of a coded-aperture camera with a large-area (approximately 0.5 square meter) CdZnTe detector array. The hardware is currently in final stages of fabrication and initial stages of integration and test. Key components of the mission are vigorous follow-up and outreach programs to engage the astronomical community and public in Swift.

Gehrels, Neil↗

Logistics Reduction Advancements and Future Plans for NASA's Exploration Missions

Management of logistics on exploration missions includes both looking for ways to minimize the quantities, mass and volume of various consumables, supplies, spares, and equipment as well as ways to minimize the crew time needed for locating and handling those items. Also included are ways to minimize the waste, handling, and resultant products from the processes of maintaining a crew on these missions. The Logistics Reduction project encompasses technologies for management of waste, trash, autonomous logistics, and clothing. This paper provides a status of work from 2023 in these areas including recent accomplishments and challenges encountered. Future objectives and plans for 2024 will also be covered along with the work currently in progress. Specifically, the paper will cover technologies in waste management, namely, the Universal Waste Management System (UWMS) or exploration toilet and work on an alternative waste collection container, the Alternate Fecal Canister. Trash management technologies work on the Trash Compaction Processing System (TCPS) and Trash to Gas (TtG) is summarized with progress to date as well as information on how Jettison as an option is related. Progress and summary of recent accomplishment on the RFID (Radio Frequency ID) Enabled Autonomous Logistics Management (REALM) and the Autonomous Logistics (AL) technologies is detailed. Advanced Clothing System (ACS) and work in the area of Systems Engineering and Integration (SE&I) is also included. Status of the technologies, accomplishments and how the focus areas inform program decisions will be addressed.

Toilet↗

Logistics Reduction Advancements and Future Plans for NASA's Exploration Missions

Management of logistics on exploration missions includes both looking for ways to minimize the quantities, mass and volume of various consumables, supplies, spares, and equipment as well as ways to minimize the crew time needed for locating and handling those items. Also included are ways to minimize the waste, handling, and resultant products from the processes of maintaining a crew on these missions. The Logistics Reduction project encompasses technologies for management of waste, trash, autonomous logistics, and clothing. This paper provides a status of work from 2023 in these areas including recent accomplishments and challenges encountered. Future objectives and plans for 2024 will also be covered along with the work currently in progress. Specifically, the paper will cover technologies in waste management, namely, the Universal Waste Management System (UWMS) or exploration toilet and work on an alternative waste collection container, the Alternate Fecal Canister. Trash management technologies work on the Trash Compaction Processing System (TCPS) and Trash to Gas (TtG) is summarized with progress to date as well as information on how Jettison as an option is related. Progress and summary of recent accomplishment on the RFID (Radio Frequency ID) Enabled Autonomous Logistics Management (REALM) and the Autonomous Logistics (AL) technologies is detailed. Advanced Clothing System (ACS) and work in the area of Systems Engineering and Integration (SE&I) is also included. Status of the technologies, accomplishments and how the focus areas inform program decisions will be addressed.

Toilet↗

Logistics Reduction Advancements and Future Plans for NASA's Exploration Missions

Management of logistics on exploration missions includes both looking for ways to minimize the quantities, mass and volume of various consumables, supplies, spares, and equipment as well as ways to minimize the crew time needed for locating and handling those items. Also included are ways to minimize the waste, handling, and resultant products from the processes of maintaining a crew on these missions. The Logistics Reduction project encompasses technologies for management of waste, trash, autonomous logistics, and clothing. This paper provides a status of work from 2023 in these areas including recent accomplishments and challenges encountered. Future objectives and plans for 2024 will also be covered along with the work currently in progress. Specifically, the paper will cover technologies in waste management, namely, the Universal Waste Management System (UWMS) or exploration toilet and work on an alternative waste collection container, the Alternate Fecal Canister. Trash management technologies work on the Trash Compaction Processing System (TCPS) and Trash to Gas (TtG) is summarized with progress to date as well as information on how Jettison as an option is related. Progress and summary of recent accomplishment on the RFID (Radio Frequency ID) Enabled Autonomous Logistics Management (REALM) and the Autonomous Logistics (AL) technologies is detailed. Advanced Clothing System (ACS) and work in the area of Systems Engineering and Integration (SE&I) is also included. Status of the technologies, accomplishments and how the focus areas inform program decisions will be addressed.

Toilet↗