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At least 37 records · Page 2

Some structural features of unsteady separating turbulent shear flows

Some physical features of unsteady separating turbulent boundary layers are presented for practical Reynolds numbers and reduced frequencies for helicopter and turbomachinery flows. Upstream of detachment in moderate amplitude flows, the flow is quasi steady, i.e., the phase averaged flow is described by the steady-free stream flow structure. Results show that oscillation waveform and amplitude strongly influence the detached flow behavior.

Simpson, R. L.

Biophysical and Structural Features of αβT ‐Cell Receptor Mechanosensing: A Paradigmatic Shift in Understanding T‐Cell Activation

ABSTRACT αβT cells protect vertebrates against many diseases, optimizing surveillance using mechanical force to distinguish between pathophysiologic cellular alterations and normal self‐constituents. The multi‐subunit αβT‐cell receptor (TCR) operates outside of thermal equilibrium, harvesting energy via physical forces generated by T‐cell motility and actin‐myosin machinery. When a peptide‐bound major histocompatibility complex molecule (pMHC) on an antigen presenting cell is ligated, the αβTCR on the T cell leverages force to form a catch bond, prolonging bond lifetime, and enhancing antigen discrimination. Under load, the αβTCR undergoes reversible structural transitions involving partial unfolding of its clonotypic immunoglobulin‐like (Ig) domains and coupled rearrangements of associated CD3 subunits and structural elements. We postulate that transitions provide critical energy to initiate the signaling cascade via induction of αβTCR quaternary structural rearrangements, associated membrane perturbations, exposure of CD3 ITAMs to phosphorylation by non‐receptor tyrosine kinases, and phase separation of signaling molecules. Understanding force‐mediated signaling by the αβTCR clarifies long‐standing questions regarding αβTCR antigen recognition, specificity and affinity, providing a basis for continued investigation. Future directions include examining atomistic mechanisms of αβTCR signal initiation, performance quality, tissue compliance adaptability, and T‐cell memory fate. The mechanotransduction paradigm will foster improved rational design of T‐cell based vaccines, CAR‐Ts, and adoptive therapies.

Immunology

Unraveling the Atomic Mechanism of the Crystalline Phase‐Dependent Structural Features and Special Spectral Design of α‐, β‐, and Ɛ‐Ga₂O₃

Atomic‐scale phase transformations profoundly influence the functional properties of Ga₂O₃ polymorphs. By combining irradiation experiments with microstructure characterization and theoretical approaches, phase‐specific energy‐dissipation pathways in α‐, β‐, and ε‐Ga₂O₃ are uncovered and strategies for targeted property design are outlined. Competing antiphase boundaries (APBs) and twin domain boundaries (TDBs) promote irreversible α→ε interconversion through domain fragmentation. In β‐Ga₂O₃, defect‐induced stress gradients drive two distinct local transformations: surface Ga‐aggregated β→δ that stabilizes transient states, and latent‐track‐confined β→κ phase transition with recoverable distortions via cation reordering. Under electronic excitation, β‐Ga₂O₃ forms nanohillocks via robust GaO₆ octahedra (high density/strong Ga─O bonds), while α/ε‐Ga₂O₃ generates nanopores from tetrahedral Ga looseness (low bonding energy), highlighting phase‐dependent surface dynamics shaped by atomic packing and bonding anisotropy. Defect‐regulated recombination suppresses visible photoluminescence in α/β‐Ga₂O₃, whereas in ε‐Ga₂O₃ bandgap narrowing of ΔE: 0.30 eV is observed, enhancing emission. Linking phase‐dependent defect‐carrier interactions and metastable‐phase engineering in Ga₂O₃ enables property optimization for power‐electronics and optoelectronics devices.

electronic state configuration

Capability of ERTS-1 imagery to investigate geological and structural features in a sedimentary basin (Bassin Parisien, France)

The author has identified the following significant results. The region covered by the MSS images has the benefit of complete geological mapping at scales of 1:80,000, 1:320,000, and 1:1,000,000. Comparison of imagery and exisiting geological maps, particularly the 1:1,000,000 scale, produces important information: (1) Good correspondence is seen between large units distinguished on the images and the concentric strata of the Jurassic, Cretaceous, and Paleocene on the map. (2) Comparison of MSS images with the hydrogeological map of the Parisian basin at 1:500,000 removes all ambiguity with regard to lithological variations. Among the many faults revealed, only three were considered: (1) the Metz; (2)Juranze; and (3) the double fault of the Marne. Imagery shows a conspicuous alignment of the Metz fault unknown until now and ending near Montereau against the group of north-south faults between Montargis and Bourbon l'Archambault. MSS images show that the Juranze fault divides beyond Brienne into two branches of equal importance. The northern one represents the known fault, the southern one was not known until now, but the convergence of the faults constitutes a tectonic trap. The double fault of the Marne is known for a total length of 50 km. ERTS-1 imagery suggest a prolongation toward the southeast which could bring its length to 110 km.

Weecksteen, G.

An interpretation of volcanic and structural features of crater Aitken

Detailed observations from the study of Apollo 17 panoramic photography of the Aitken crater are reported which suggest that there has been significant late-stage compressional deformation of the crater and its adjacent highlands. A speculative interpretation of eruptive activity and drain-back events within Aitken is presented, which leads to the conclusion that hummocky topography within certain cones represents collapsed lava rather than extrusive domes. That is, eruptive activity within Aitken probably commenced with an explosive cone-building stage, followed by lava eruptions from cones and fissures, and ended with drain-back restricted to the relatively deep lava ponded in the vents.

Bryan, W. B.

Structural features of the nonionic surfactants stabilizing long-lived bubble nuclei

A study of the effects of various electrolytes and one organic compound on bubble production in agarose gels is presented. Several preparations of ultrapure agarose were compared for 42 electrolytes and phenol to identify trends in bubble formation. The anion and cation sequences of bubble suppression are similar to processes for salting out of nonionic surfactants. The reduction of bubble number by polyvalent ions and 1% phenol suggests that the polar portions of these nonionic surfactants represent amide groups. The evidence for amide groups is consistent with the relative positions of Mg(2+) in all cation sequences; this result makes it unlikely that either linkages contribute to the hydrophilicity of the nonionic surfactants stabilizing bubble nuclei in the different aqueous gels tested.

Darrigo, J. S.

Pattern, age, and origin of structural features within the Ozark plateau and the relationship to ore deposits

Topography and gravity anomaly images for the continental United States were constructed. Evidence was found based on gravity, remote sensing data, the presence, trend, and character of fractures, and on rock type data, for a Precambrian rift through Missouri. The feature is probably the failed arm of a triple junction that existed prior to formation of the granite-rhyolite terrain of southern Missouri.

Arvidson, R. E.

Atmospheric pressure chemical ionization studies of non-polar isomeric hydrocarbons using ion mobility spectrometry and mass spectrometry with different ionization techniques

The ionization pathways were determined for sets of isomeric non-polar hydrocarbons (structural isomers, cis/trans isomers) using ion mobility spectrometry and mass spectrometry with different techniques of atmospheric pressure chemical ionization to assess the influence of structural features on ion formation. Depending on the structural features, different ions were observed using mass spectrometry. Unsaturated hydrocarbons formed mostly [M - 1]+ and [(M - 1)2H]+ ions while mainly [M - 3]+ and [(M - 3)H2O]+ ions were found for saturated cis/trans isomers using photoionization and 63Ni ionization. These ionization methods and corona discharge ionization were used for ion mobility measurements of these compounds. Different ions were detected for compounds with different structural features. 63Ni ionization and photoionization provide comparable ions for every set of isomers. The product ions formed can be clearly attributed to the structures identified. However, differences in relative abundance of product ions were found. Although corona discharge ionization permits the most sensitive detection of non-polar hydrocarbons, the spectra detected are complex and differ from those obtained with 63Ni ionization and photoionization. c. 2002 American Society for Mass Spectrometry.

Non-NASA Center