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At least 37 records · Page 2

A 100Mbps coherent optical link demonstration using frequency stabilized solid state lasers

The design, implementation, and performance evaluation of a 100Mbps binary phase shift keying (BPSK) coherent optical link using frequency stabilized solid state lasers is described. In this demonstration, the transmitted data is binary phase modulated at 100Mbps using an external resonant cavity phase modulator. At the receiving end, the signal is detected using a balanced heterodyne detector. An auxiliary frequency tracking loop (FTL) is used to help the initial frequency acquisition before handing over to the carrier phase tracking loop. The FTL is implemented using a delay line discriminator, and the detected frequency error is fed back to the local oscillator laser to close the tracking loop. Phase coherent reception is achieved by synchronizing the carrier phase using a Costas tracking loop. The demonstration showed that a high data rate phase coherent optical link can be implemented using frequency stabilized solid state lasers.

Chen, CHIEN-C.↗

Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited in response to inotropic interventions

Mavacamten is a FDA-approved small-molecule therapeutic designed to regulate cardiac function at the sarcomere level by selectively but reversibly inhibiting the enzymatic activity of myosin. It shifts myosin toward ordered off states close to the thick filament backbone. It remains elusive whether these myosin heads in the off state(s) can be recruited in response to physiological stimuli when required to boost cardiac output. We show that cardiac myosins stabilized in these off state(s) by mavacamten are recruitable by 1) Ca 2+ , 2) increased chronotropy [heart rate (HR)], 3) stretch, and 4) β-adrenergic (β-AR) stimulation, all known physiological inotropic interventions. At the molecular level, we show that Ca 2+ increases myosin ATPase activity by shifting mavacamten-stabilized myosin heads from the inactive super-relaxed state to the active disordered relaxed state. At the myofilament level, both Ca 2+ and passive lengthening can shift mavacamten-ordered off myosin heads from positions close to the thick filament backbone to disordered on states closer to the thin filaments. In isolated rat cardiomyocytes, increased stimulation rates enhanced shortening fraction in mavacamten-treated cells. This observation was confirmed in vivo in telemetered rats, where left-ventricular dP/dt max , an index of inotropy, increased with HR in mavacamten-treated animals. Finally, we show that β-AR stimulation in vivo increases left-ventricular function and stroke volume in the setting of mavacamten. Our data demonstrate that the mavacamten-promoted off states of myosin in the thick filament are at least partially activable, thus preserving cardiac reserve mechanisms.

59 BASIC BIOLOGICAL SCIENCES↗

Low data rate coherent optical link demonstration using frequency stabilized solid state lasers

A low data rate laboratory heterodyne link demonstration operating at 1.06 micron using frequency stabilized Nd:YAG lasers was implemented. The data was modulated onto the optical carrier at 100 kbps using binary pulse position modulation. Phase coherent reception was achieved by closing the receiver phase tracking loop around the piezo-electric and temperature-tuned local oscillator laser. Initial frequency acquisition was accomplished by linearly scanning the LO frequency over the uncertainty range while a combined frequency and phase tracking loop searches for a lock indicator signal. The link performance was experimentally evaluated and compared to the theoretical predictions.

Chen, CHIEN-C.↗

Using genetic algorithms to discover novel ground-state triplet conjugated polymers

Stable ground-state triplet π-conjugated copolymers have many interesting electronic and optoelectronic properties. However, the large number of potential monomer combinations makes it impractical to synthesize or even just use density functional theory (DFT) to calculate their triplet ground-state stability. Furthermore, we present a genetic algorithm implementation that uses the semi-empirical GFN2-xTB to find ground-state triplet polymer candidates. We find more than 1400 polymer candidates with a triplet ground-state stability of up to 4 eV versus the singlet. Additionally, we explore the properties of the monomers of those candidates in order to understand the design rules which promote the formation of a stable ground-state triplet in π-conjugated polymers.

36 MATERIALS SCIENCE↗

Transonic Correction Method for Flight Dynamic Stability Analysis of Mach 0.745 Transonic Truss-Braced Wing

This paper presents a transonic correction method for obtaining dynamic stability derivatives for flight dynamic stability analysis. The method provides a transonic correction to the Theodorsen's theory of unsteady aerodynamics using FUN3D CFD solver of unsteady Reynolds-averaged Navier-Stokes equations (RANS) for a series of wing sections of the Mach 0.745 Transonic Truss-Braced Wing in pitch and plunge oscillations. Unsteady lift and pitching moment coefficients are obtained and used to develop the correction terms in the Theodorsen's theory to account for transonic aerodynamics. The unsteady lift and pitching moment derivatives with respect to the unsteady angle of attack are obtained as frequency response functions of the reduced frequency. These frequency response functions are used to compute the dynamic stability derivatives of lift and pitching moment due to the angle of attack and pitch rate and the dynamic stability derivatives for the rolling moment and yawing moment with respect to the roll rate and yaw rate. A transonic correction is applied to steady-state stability derivatives computed by VSPAERO solver using transonic small disturbance code TSFOIL coupled to an integral boundary method. A dynamic stability analysis is conducted for longitudinal and lateral-directional motions. Without transonic corrections and dynamic stability derivatives, the analysis indicates an unstable phugoid mode. The transonic correction applied to the steady-state stability derivatives computed by VSPAERO shows a stable phugoid mode. This is due to the increase of the drag stability derivatives as a result of the additional wave drag contribution in transonic flow. The effect of the transonic dynamic stability derivatives is observed to be a significant contributor to the increase in the damping values of all the flight dynamic modes of the Mach 0.745 Transonic-Truss Braced Wing.

Transonic↗

CFD-Based Frequency Domain Method for Dynamic Stability Derivative Estimation with Application to Transonic Truss-Braced Wing

This paper presents a dynamic stability estimation technique obtained from high-fidelity CFD simulations of the Mach 0.8 Transonic Truss-Braced Wing (TTBW). A series of unsteady RANS CFD simulations in FUN3D is performed on the TTBW in pitch and plunge oscillations at various reduced frequencies. The time-domain data are transformed into the frequency-domain data by Fourier series. Transfer functions of the dynamic stability derivatives are then estimated by a frequency-domain regression. The dynamic stability derivatives with respect to the angle of attack are determined by the regression of the unsteady aerodynamic coefficients for the plunge motion. The dynamic stability derivatives with respect to the pitch rate are deter-mined by the regression of the differential unsteady aerodynamic coefficients for the pitch motion upon the removal of the angle of attack contribution by the plunge motion. The steady-state stability derivatives are then compared to the results obtained from a stability analysis code VSPAERO as well as steady-state FUN3D simulations. The comparison of the steady-state stability derivatives shows excellent agreement.

Dynamic Stability Derivatives↗

A structural framework for unidirectional transport by a bacterial ABC exporter

The ATP-binding cassette (ABC) transporter of mitochondria (Atm1) mediates iron homeostasis in eukaryotes, while the prokaryotic homolog from Novosphingobium aromaticivorans (NaAtm1) can export glutathione derivatives and confer protection against heavy-metal toxicity. To establish the structural framework underlying the NaAtm1 transport mechanism, we determined eight structures by X-ray crystallography and single-particle cryo-electron microscopy in distinct conformational states, stabilized by individual disulfide crosslinks and nucleotides. As NaAtm1 progresses through the transport cycle, conformational changes in transmembrane helix 6 (TM6) alter the glutathione-binding site and the associated substrate-binding cavity. Significantly, kinking of TM6 in the post-ATP hydrolysis state stabilized by MgADPVO4 eliminates this cavity, precluding uptake of glutathione derivatives. The presence of this cavity during the transition from the inward-facing to outward-facing conformational states, and its absence in the reverse direction, thereby provide an elegant and conceptually simple mechanism for enforcing the export directionality of transport by NaAtm1. One of the disulfide crosslinked NaAtm1 variants characterized in this work retains significant glutathione transport activity, suggesting that ATP hydrolysis and substrate transport by Atm1 may involve a limited set of conformational states with minimal separation of the nucleotide-binding domains in the inward-facing conformation.

59 BASIC BIOLOGICAL SCIENCES↗

The Triple Component Interface of Ni–Co–Ce: Growth, Chemical State, and Stability of NiCo Bimetallic Particles on Reducible CeO 2 (111) Thin Films

The growth of NiCo particles at low coverages over reducible CeO 2 (111) thin films producing a triple interface between Ni-Co-Ce was investigated by scanning tunneling microscopy (STM) and X-ray photoelectron spectroscopy (XPS), which was compared to that of monometallic Ni and Co particles. XPS data show that deposition of either Ni or Co on CeO 2 at 300 K causes a partial reduction of Ce 4+ cations to Ce 3+ ions. At 0.3 monolayer (ML), XPS detects Co 2+ on CeO 2 . However, both Ni 0 and Ni 2+ are present as major species at 300 K and annealing causes a significant increase of Ni 2+ in Ni particles. Deposition of 0.3 ML Co over 0.3 ML Ni on CeO 2 at 300 K induces reduction of Ni 2+ to metallic Ni and Ni 0 was found as predominant species. Unlike for Co/CeO 2 , metallic Co was also present over the Co-Ni/CeO 2 surface in addition to Co 2+ . Further, this behavior indicates the formation of NiCo bimetallic particles with the possibility of Co diffusion to the interface of Ni/ceria. With heating, the intermixing of Ni and Co atoms in bimetallic particles on CeO 2 was facilitated. Furthermore, oxidation of both metals and ceria occurred as a result of the diffusion of lattice oxygen from the bulk of ceria to the surface. A slight increase in Ni 2+ was observed after heating Co-Ni/CeO 2 to 500 K or higher. Co became Co 2+ with heating to 800 K. Our STM results confirm the formation of NiCo bimetallic particles on CeO 2 at 300 K and further suggest that the addition of Co can help inhibit the sintering of Ni particles at higher temperatures. Bimetallic particles were also obtained by depositing Ni over existing Co particles on CeO 2 . However, our XPS data demonstrate that the deposition order of Co and Ni plays a role in the chemical state of these two metals in bimetallic particles, likely attributed to the difference in their compositions at the bimetallic particle surface as well as the metal-support interface.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Gradient-Descent-Based Learning Gain for Backstepping Controller and Disturbance Observer of Nonlinear Systems

This paper proposes a gradient-descent-based learning (GL) gain for backstepping controller and disturbance observer (DOB) of nonlinear system. The proposed method consists of the GL gain update law, controller, and DOB. The GL gain update law is proposed to adapt the control gain and DOB gain according to the direction that minimizes the cost function. The mathematical analysis reveals that the GL gain always has a positive sign and upper bound. The controller is designed via a backstepping procedure to track the desired output with GL control gain. The DOB is designed to estimate the unknown external disturbance with the GL DOB gain. Because the control and DOB gains are simultaneously tuned to achieve improved performance, the time consumption for tuning can be reduced. In addition, the peaking phenomenon can be avoided initially by a small initial value of GL gains. The stability of the closed-loop system is guaranteed using the input-to-state stability property. The performance of the proposed method was validated via simulations and experiments using a DC motor.

42 ENGINEERING↗

Steady and Unsteady Simulations of Transonic Truss-BracedWing Aircraft for Flight Dynamic Stability Analysis

This paper presents steady and unsteady simulations of the Mach 0.8 and Mach 0.745Transonic Truss-Braced Wing (TTBW) aircrafts using the high-fidelity CFD solver FUN3D for the flight dynamic stability analysis. The steady-state stability derivatives with respect to the angle of attack, angle of sideslip, and airspeed are calculated with perturbations in the angle of attack, angle of sideslip, and Mach number, respectively. A series of unsteady CFD simulations conducted for the TTBW aircrafts in pitch oscillation at various reduced frequencies. The dynamic stability derivatives are estimated using a frequency domain estimation method. The results are then compared to the results obtained from the VSPAERO stability analysis.

CFD↗

Noise-induced stabilization of dynamical states with broken time-reversal symmetry

Under a high frequency drive, Josephson junctions demonstrate Shapiro steps of quantized voltage. These are dynamically stabilized states in which the phase across the junction locks to the external drive. We explore the stochastic switching between two symmetric steps at $\frac{hw}{2e}$ and –$\frac{hw}{2e}$. Surprisingly, the switching rate exhibits a pronounced nonmonotonicity as a function of temperature, violating the general expectation that transitions should become faster with temperature. As a result, we explain this behavior by realizing that the system retains memory of the dynamic state from which it is switching, thereby breaking the conventional simplifying assumptions about separations of timescales.

36 MATERIALS SCIENCE↗

On the dependence of travelling wave stability on basic state wave phase speed

The dependence of stability on basic state wave phase speed is examined in a nondivergent barotropic model on a sphere for planetary scale waves with phase speeds typical of waves observed in the atmosphere. Triad interactions are examined analytically and compared to numerical results from a full spectral model. A number of triads may result in growth of the perturbation components for each basic state wave; for each triad there is a basic state wave phase speed where it is resonant, identified as the point where the critical amplitude for instability to that perturbation becomes zero. Critical amplitudes for instability obtained using the full spectral model generally agree well with triad results. Since the basic state wave phase speed determines which triad will grow, spatial structure and critical amplitudes for instability for the growing disturbances depend strongly on basic state wave phase speed. The results of this idealized study suggest that phase speed may be an important factor in determining the stability of planetary scale waves in the atmosphere.

Manney, Gloria L.↗

The quantum entropy cone of hypergraphs

In this work, we generalize the graph-theoretic techniques used for the holographic entropy cone to study hypergraphs and their analogously-defined entropy cone. This allows us to develop a framework to efficiently compute entropies and prove inequalities satisfied by hypergraphs. In doing so, we discover a class of quantum entropy vectors which reach beyond those of holographic states and obey constraints intimately related to the ones obeyed by stabilizer states and linear ranks. We show that, at least up to 4 parties, the hypergraph cone is identical to the stabilizer entropy cone, thus demonstrating that the hypergraph framework is broadly applicable to the study of entanglement entropy. We conjecture that this equality continues to hold for higher party numbers and report on partial progress on this direction. To physically motivate this conjectured equivalence, we also propose a plausible method inspired by tensor networks to construct a quantum state from a given hypergraph such that their entropy vectors match.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

NASTRAN/FLEXSTAB procedure for static aeroelastic analysis

Presented is a procedure for using the FLEXSTAB External Structural Influence Coefficients (ESIC) computer program to produce the structural data necessary for the FLEXSTAB Stability Derivatives and Static Stability (SD&SS) program. The SD&SS program computes trim state, stability derivatives, and pressure and deflection data for a flexible airplane having a plane of symmetry. The procedure used a NASTRAN finite-element structural model as the source of structural data in the form of flexibility matrices. Selection of a set of degrees of freedom, definition of structural nodes and panels, reordering and reformatting of the flexibility matrix, and redistribution of existing point mass data are among the topics discussed. Also discussed are boundary conditions and the NASTRAN substructuring technique.

Schuster, L. S.↗

Magnetic Field-Stabilized Wigner Crystal States in a Graphene Moiré Superlattice

ABC-stacked trilayer graphene on boron nitride (ABC-TLG/hBN) moiré superlattices provides a tunable platform for exploring Wigner crystal states in which the electron correlation can be controlled by electric and magnetic fields. Here, in this work, we report the observation of magnetic field-stabilized Wigner crystal states in a ABC-TLG/hBN. We show that correlated insulating states emerge at multiple fractional and integer fillings corresponding to ν = 1/3, 2/3, 1, 4/3, 5/3, and 2 electrons per moiré lattice site under a magnetic field. These correlated insulating states can be attributed to generalized Mott states for the integer fillings and generalized Wigner crystal states for the fractional fillings. The generalized Wigner crystal states are stabilized by a vertical magnetic field and are strongest at one magnetic flux quantum per three moiré superlattices. The ν = 2 insulating state persists up to 30 T, which can be described by a Mott–Hofstadter transition at a high magnetic field.

77 NANOSCIENCE AND NANOTECHNOLOGY↗