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At least 37 records · Page 2

Addendum: Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale

In response to a reader’s questions, here we provide additional information about the life cycle analysis (LCA) performed in this paper. The goal of the LCA was to understand the potential environmental benefits of our reported synthetic biology pathways for producing acetone and isopropanol by comparing greenhouse gas emissions to those from conventional, virgin fossil production routes. Below we expand on the rationale and sources underlying the methodological choices we made in the LCA, including our use of a cradle-to-gate system boundary, an avoided emissions credit and the descriptor “carbon-negative.” Finally, we also discuss differences in carbon accounting between an LCA framework and a carbon dioxide removal (CDR) framework.

metabolic engineering↗

Spectral shaping of an ultrafast ytterbium fiber laser via a passive intracavity optical filter: a simple and reliable route to sub-45 fs pulses

We investigate the use of passive intracavity optical filters for controlling the laser output spectrum of a polarization-mode-locked, ultrafast ytterbium fiber laser. The overall lasing bandwidth is increased or extended by strategic choice of the filter cutoff frequency. Overall laser performance, including pulse compression and intensity noise, is investigated for both shortpass and longpass filters with a range of cutoff frequencies. The intracavity filter not only shapes the output spectra, but also provides a route for overall broader bandwidths and shorter pulses in ytterbium fiber lasers. These results demonstrate that spectral shaping with a passive filter is a useful tool to routinely achieve sub-45 fs pulse durations in ytterbium fiber lasers.

Cooper, Nicholas D.↗

A Flight Replanning Tool for Terminal Area Urban Air Mobility Operations

In this presentation we describe and evaluate a flight replanning tool, called the trial planner, for terminal area air transport applications. The trial planner employs predefined airspace structures to generate rerouting options between vertiports. In a simplified definition, vertiports are facilities that provide services for managing the take-off and landing of autonomous or manned electric vertical take-off or landing (eVTOL) aircraft. The airspace structures involved in our test cases are arrival routes that consist of predefined entry points to which a transitional path is computed dynamically from the current position of the aircraft. Rerouting options include the transitional path and approach segment along the arrival route; these rerouting options are not vetted for potential conflicts with other operations until a human operator commits to a choice and forwards the flight plan modification for approval from an automated airspace management service. A selected rerouting option is executed by loading a flight plan file to the aircraft ground control station. We conducted a qualitative evaluation of the trial planner using ratings provided by flight crews and air transportation human factors experts with relevant experience from air traffic control. Evaluation criteria included trust in the route recommendations and adequate explanation for the route options. We detail the logic and implementation of the trial planner, as well as report the results of the evaluation of the implementation herein.

Trial planning↗

BSMV-mediated genome editing exhibits host-specific heritability: germline transmission in barley and somatic edits in Nicotiana benthamiana

Plant RNA virus–mediated guide RNA (gRNA) delivery represents a transformative advance in genome editing technologies. Unlike conventional transformation methods that rely on labor-intensive tissue culture and regeneration for each individual gRNA delivery, viral vectors can rapidly and systemically transmit gRNAs into pre-established Cas-expressing plants, providing an accelerated route for functional genomics and trait discovery directly in planta . However, key design parameters, including subgenomic promoter choice, transcript architecture, and their effects on viral fitness and editing outcomes, remain to be elucidated for most viral platforms. We developed five Barley stripe mosaic virus (BSMV) vectors, each with distinct subgenomic promoter elements to drive single gRNA expression. These were initially evaluated in Cas9-expressing transgenic Nicotiana benthamiana plants targeting the Phytoene desaturase ( PDS ) gene to compare their editing efficiencies. Single gRNAs expressed under the duplicated γb subgenomic promoter or when fused directly to the γb genome achieved the highest mutation frequencies (up to 90% at 60 days post-inoculation), whereas β1- and β2-driven sgRNAs produced delayed and reduced editing. Thus, promoter selection critically determines gRNA accumulation and the efficacy of BSMV-mediated genome editing. The top-performing design was then applied to Cas9-expressing barley ( Hordeum vulgare ) targeting HvCMF7 (conferring green-white variegation) and HvGW2.1 (impacts grain width and weight). BSMV spread systemically throughout barley, inducing somatic and heritable mutations at frequencies up to 100%, with virus-free edited progeny. In contrast, despite robust somatic editing in N. benthamiana, no heritable mutations were detected indicating species-dependent limitations in germline transmission. Our systematic comparison of subgenomic promoter architectures establishes clear design principles for optimizing viral vector–mediated delivery. Promoter choice and transcript structure critically shape editing efficiency and viral stability. The host-specific boundary for germline editing, defined by efficient heritable editing in barley but not N. benthamiana , highlights where BSMV offers advantages and where alternative vectors or hybrid strategies are required, guiding rational platform selection for diverse crop species and applications. Collectively, these findings establish BSMV as a promising next-generation vector for rapid, tissue culture–free, and transformation-independent genome editing in cereals and other recalcitrant monocots.

barley↗

Editors’ Choice—Molten Salt Electrolysis in Chloride Melts for Energy-Efficient Iron Metal Production

This study explores chloride molten salt electrolysis (CMSE) as a promising route for energy-efficient iron metal (Fe) production. Moderate temperature (500 °C) LiCl-KCl molten salts offer excellent thermodynamic stability, high ionic conductivity and diffusivity, and high solubility for FeCl 3 , thereby enabling efficient Fe metal extraction at high electrowinning rates. Here, we demonstrate the two essential steps for converting taconite ore into Fe metal. First, Fe 2 O 3 from taconite pellets was selectively leached in HCl yielding a high-purity FeCl 3 aqueous solution, while the gangue components settled at the bottom. Then, anhydrous FeCl 3 was electrolyzed in a LiCl-KCl eutectic molten salt at 500 °C at high current density (1 A cm −2 ) and at high Coulombic efficiency (>85%). Analysis of the electrowon Fe deposits revealed dendritic structures with purity of >99 wt%, which could be further improved to nearly 100 wt% through arc re-melting. CMSE offers low specific energy consumption (3.7 kWhr kg −1 ), competitive with H 2 -DRI and other electrolytic approaches being pursued globally. Our findings underscore the potential of CMSE as an energy-efficient route for electrosynthesis of Fe metal.

36 MATERIALS SCIENCE↗

Production of bio-based lactones as monomers for a circular polymer economy

To create a circular plastics economy, new polymers are being developed that can be chemically recycled. Circular polyesters are of particular interest and to this end, lactones are ideal monomers. Here, this Review examines catalytic routes to convert diols, hydroxy acids, and dicarboxylic acids to lactones, focusing on the development of scalable, atom-economic, and energy-efficient conversions of bio-derived feedstocks. Free energy analysis is used to inform process choices, such as reactor type, reaction phase, and use of solvent. Catalyst design principles are summarized for both direct (bio-substrate to lactone) and indirect (bio-substrate to intermediate to lactone) routes. Finally, we summarize literature that shows that many lactone precursors are readily accessible from various metabolic and chemo-catalytic pathways. Transitioning to bio-based monomers offers an opportunity to reduce reliance on fossil carbon resources, but requires advanced catalytic processes informed by mechanistic insights.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Two Artificial Leaf Architectures for Solar Formate Production From CO 2 and H 2 O

Sunlight-powered artificial leaves for the production of formate from CO 2 are an attractive route to solar fuels, yet existing solar formate devices remain low in performance, and their architecture and material choices are underexplored. Herein, we report the fabrication of two distinct fully integrated, self-standing solar formate device architectures and elucidate the underlying design principles and material selection strategies. The first architecture integrates a Si photocathode with a BiVO 4 photoanode and utilizes a highly active Pd catalyst for CO 2 reduction. It represents the first artificial leaf device comprising two photoelectrodes (excluding photovoltaic [PV]-biased electrodes) for effective formate production under single-beam illumination. The second architecture employs a dark cathode and a dark anode driven by a 4-junction perovskite solar cell and uses a highly stable Bi catalyst for CO 2 reduction. This device delivers a record-high formate production rate of 174 µmol h −1 with a remarkable solar-to-formate energy efficiency of 2% among all artificial leaf devices reported to date. Finally, these results demonstrate the feasibility and outline the design principles of both PV-free and PV-assisted device architectures in solar fuel production.

electrocatalysis↗

Route Monopolie and Optimal Nonlinear Pricing

To cope with air traffic growth and congested airports, two solutions are apparent on the supply side: 1) use larger aircraft in the hub and spoke system; or 2) develop new routes through secondary airports. An enlarged route system through secondary airports may increase the proportion of route monopolies in the air transport market.The monopoly optimal non linear pricing policy is well known in the case of one dimension (one instrument, one characteristic) but not in the case of several dimensions. This paper explores the robustness of the one dimensional screening model with respect to increasing the number of instruments and the number of characteristics. The objective of this paper is then to link and fill the gap in both literatures. One of the merits of the screening model has been to show that a great varieD" of economic questions (non linear pricing, product line choice, auction design, income taxation, regulation...) could be handled within the same framework.VCe study a case of non linear pricing (2 instruments (2 routes on which the airline pro_ddes customers with services), 2 characteristics (demand of services on these routes) and two values per characteristic (low and high demand of services on these routes)) and we show that none of the conclusions of the one dimensional analysis remain valid. In particular, upward incentive compatibility constraint may be binding at the optimum. As a consequence, they may be distortion at the top of the distribution. In addition to this, we show that the optimal solution often requires a kind of form of bundling, we explain explicitly distortions and show that it is sometimes optimal for the monopolist to only produce one good (instead of two) or to exclude some buyers from the market. Actually, this means that the monopolist cannot fully apply his monopoly power and is better off selling both goods independently.We then define all the possible solutions in the case of a quadratic cost function for a uniform distribution of agent types and explain the implications for airlines in terms of service differentiation.

Tournut, Jacques↗

Analysis of the Capacity Potential of Current Day and Novel Configurations for New York's John F. Kennedy Airport

In 2015, a series of systems analysis studies were conducted on John F. Kennedy Airport in New York (NY) in a collaborative effort between NASA and the Port Authority of New York and New Jersey (PANYNJ). This work was performed to build a deeper understanding of NY airspace and operations to determine the improvements possible through operational changes with tools currently available, and where new technology is required for additional improvement. The analysis was conducted using tool-based mathematical analyses, video inspection and evaluation using recorded arrival/departure/surface traffic captured by the Aerobahn tool (used by Kennedy Airport for surface metering), and aural data archives available publically through the web to inform the video segments. A discussion of impacts of trajectory and operational choices on capacity is presented, including runway configuration and usage (parallel, converging, crossing, shared, independent, staggered), arrival and departure route characteristics (fix sharing, merges, splits), and how compression of traffic is staged. The authorization in March of 2015 for New York to use reduced spacing under the Federal Aviation Administration (FAA) Wake Turbulence Recategorization (RECAT) also offers significant capacity benefit for New York airports when fully transitioned to the new spacing requirements, and the impact of these changes for New York is discussed. Arrival and departure capacity results are presented for each of the current day Kennedy Airport configurations. While the tools allow many variations of user-selected conditions, the analysis for these studies used arrival-priority, no-winds, additional safety buffer of 5% to the required minimum spacing, and a mix of traffic typical for Kennedy. Two additional "novel" configurations were evaluated. These configurations are of interest to Port Authority and to their airline customers, and are believed to offer near-term capacity benefit with minimal operational and equipage changes. One of these is the addition of an Optimized Profile Descent (OPD) route to runways 22L and 22R, and the other is the simultaneous use of 4 runways, which is not currently done at Kennedy. The background and configuration for each of these is described, and the capacity results are presented along with a discussion of drawbacks and enablers for each.

Glaab, Patricia↗

Statistical Considerations for the Design and Execution of NASA's Community Noise Surveys

The World Health Organization defines community noise as noise emitted from all sources apart from noise at an industrial workplace. Example sources include neighborhood and construction noise, noise from road and rail, and air traffic noise. In particular, overland supersonic flights have been banned in the United States since the 1970s based on data accumulated during the 1960s; the degree of reported annoyance from the resulting sonic booms was a key factor leading to the prohibition. In subsequent years, scientific and engineering understanding has led to the potential to produce low amplitude sonic booms, or ‘sonic thumps’, during supersonic flight through aircraft design choices. Aircraft manufacturers have expressed renewed interest in producing supersonic commercial aircraft, but without appropriate changes to regulation, only overseas routes can be traveled supersonically. The National Aeronautics and Space Administration (NASA) will be flying the X-59 demonstrator aircraft in a series of community tests to begin in the 2024 fiscal year. In this presentation we provide some historical context for the current prohibitions on supersonic commercial flight. Using data collected during earlier NASA risk reduction tests, we demonstrate how generalized linear mixed models can be used to inform the functional dose-response response curve. Finally, we discuss some of the challenges in designing the future community studies and generalizing them to a nationally-representative dose-response curve. The study effort will be of national and international importance as the data and models prepared during the community tests will be provided to the International Civil Aviation Organization (ICAO) in order to help noise regulators determine if supersonic flight will be permitted over land once again and at what demonstrable noise levels.

Nathan B Cruze↗

Design of an advanced flight planning system

The demand for both fuel conservation and four-dimensional traffic management require that the preflight planning process be designed to account for advances in airborne flight management and weather forecasting. The steps and issues in designing such an advanced flight planning system are presented. Focus is placed on the different optimization options for generating the three-dimensional reference path. For the cruise phase, one can use predefined jet routes, direct routes based on a network of evenly spaced grid points, or a network where the grid points are existing navaid locations. Each choice has its own problem in determining an optimum solution. Finding the reference path is further complicated by choice of cruise altitude levels, use of a time-varying weather field, and requiring a fixed time-of-arrival (four-dimensional problem).

Sorensen, J. A.↗

Material‐Driven Neuronal Oscillators and Filters via Active Reactance in CC‐NDR and VC‐NDR Electro‐Thermal Memristors

The continued scaling of artificial intelligence and telecommunications hardware is increasingly constrained by the power, bandwidth, and area limitations of transistor-based circuits. Neuromorphic processor units, analog oscillators, and active inductors and capacitors rely on complex multi-transistor architectures restricting material choices and incurring energy and footprint overhead. Here, we show that active reactance in electro-thermal memristors provides an intrinsic, material driven route to neuronal oscillator dynamics and signal processing. Using a physics-based compact modeling framework, we bridge negative differential resistance (NDR) and bias-tunable reactance, which underlies spiking dynamics in electro-thermal memristors. Memristors with negative temperature coefficients of resistance (TCR) manifest current-controlled (CC-) NDR and act as active inductors, thus generating spiking above a critical circuit capacitance; whereas memristors with positive TCR manifest voltage-controlled (VC-) NDR and active capacitance, leading to spiking above a critical inductance. By creating a compact model for La 0.7 Ca 0.3 MnO 3 as a representative VC-NDR material and comparing it with LaCoO 3 manifesting CC-NDR, we explain the physical origins of their distinct current-voltage characteristics, reactive phase shifts and consequent spiking behaviors. Finally, we demonstrate tunable filtering enabled by the active reactance of electro-thermal memristors, establishing them as a compact hardware platform for neuronal oscillator functionality and integrated filtering beyond conventional CMOS.

active reactance↗

Custom-designed heat treatment simultaneously resolves multiple challenges facing 3D-printed single-crystal superalloys

Single-crystal Ni-based superalloys are currently the material of choice for turbine blade applications, especially with the emerging additive manufacturing (AM) that facilitates the manufacture/repair of these single crystals. This promising AM route, however, comes with a dilemma: in the fusion and heat affected zones after e-beam or laser induced melting, one needs a solutionizing annealing to relieve the residual stresses and homogenize the chemical/microstructure. The super-solvus solutionizing temperature is usually adopted from the protocol for the cast superalloys, which almost always causes recrystallization and stray grain growth, resulting in a polycrystalline microstructure and degrading the high-temperature mechanical performance. Here, in this paper, we demonstrate a custom-designed post-printing heat treatment to replace the conventional super-solvus one. The recovery and relatively low temperature diminish the driving force for recrystallization and the movement of stray grain boundaries, without suffocating the chemical/microstructural homogenization thanks to the narrow dendrite width and short element segregation distance. The optimal duration of the heat treatment is proposed to achieve atomic-diffusion mediated chemical homogenization while limiting γ'-particle coarsening in the interdendritic regions. Our strategy makes it practically feasible to resolve several bottleneck problems with one processing/treatment, removing a seemingly formidable obstacle to effective additive manufacturing of superalloy single crystal products.

36 MATERIALS SCIENCE↗

Overconfidence, preview, and probability in strategic planning

The performance of eight subjects in a 'rescue' video game requiring choices as to which node they should fly to in order to rescue the simulated casualties is presently studied with a view to biases and display support criteria in strategic planning. After each choice, the subjects needed to fly a challenging tracking dynamic along a path to reach the next node. The results obtained indicate that the choices of the subjects were less optimal when full preview was offered, perhaps due to subjects' reliance on the simple strategy of choosing routes with the greatest number of casualties.

Wickens, Christopher D.↗

Tetrahedral Tilting and Lithium‐Ion Transport in Halide Argyrodites Prepared by Rapid, Microwave‐Assisted Synthesis

Abstract This study demonstrates a rapid, dry, microwave‐assisted (MW) synthesis method that enables preparation of halide argyrodites ( , , ) in less than 20 min. The structures and ion transport properties of the resulting materials are compared with those synthesized by conventional solid‐state synthesis methods. The microwave‐assisted method leads to increased site disorder and elevated Arrhenius prefactors (), which lead to an order of magnitude improvement in the 30 ionic conductivity of MW‐. X‐ray pair distribution function analysis (XPDF) reveals significant rotational disorder of the units, which is impacted by the synthesis method, choice of halide, and presence of / site disorder. These rotational displacements are strongly correlated with ion transport, specifically and entropy of migration (). Overall, this study demonstrates a rapid synthesis route for preparing high‐quality halide argyrodite solid‐state electrolytes in less than 20 min, and further unravels atomistic insights into the interplay of structural disorder, rotational dynamics, and ion transport mechanisms.

36 MATERIALS SCIENCE↗

A Brief Survey of Media Access Control, Data Link Layer, and Protocol Technologies for Lunar Surface Communications

This paper surveys and describes some of the existing media access control and data link layer technologies for possible application in lunar surface communications and the advanced wideband Direct Sequence Code Division Multiple Access (DSCDMA) conceptual systems utilizing phased-array technology that will evolve in the next decade. Time Domain Multiple Access (TDMA) and Code Division Multiple Access (CDMA) are standard Media Access Control (MAC) techniques that can be incorporated into lunar surface communications architectures. Another novel hybrid technique that is recently being developed for use with smart antenna technology combines the advantages of CDMA with those of TDMA. The relatively new and sundry wireless LAN data link layer protocols that are continually under development offer distinct advantages for lunar surface applications over the legacy protocols which are not wireless. Also several communication transport and routing protocols can be chosen with characteristics commensurate with smart antenna systems to provide spacecraft communications for links exhibiting high capacity on the surface of the Moon. The proper choices depend on the specific communication requirements.

Wallett, Thomas M.↗

Effectiveness and duration of intramuscular antimotion sickness medications

Motion sickness inhibits gastric motility, making the oral route ineffective for medications. The intramuscular route is an effective alternative. The rotating chair was used to produce the M 111 level of motion sickness on the Graybiel Symptom Scale. The intramuscular medications given 30 minutes before rotation were compared with placebo (saline, 1 mL) for effectiveness and duration in increasing the number of tolerated head movements. Average placebo number of head movements was 294. Promethazine 25 mg increased head movements by 78% (P < .05), with a duration of 12 hours. Scopolamine 0.2 mg increased head movements by 91% (P < .05), with a duration of 4 hours. The effect of caffeine 250 mg and ephedrine 25 mg was not significant. When combined with scopolamine, ephedrine produced an 32% additive effect. Scopolamine 0.08 mg, 0.1 mg, and 0.2 mg and also promethazine 12.5 mg and 25 mg were significant (P < .05). Promethazine appears to be the drug of choice for intramuscular use because of a longer duration and a high level of effectiveness. Scopolamine was of high effectiveness, but had a duration of 4 hours. It was eight times as potent by the intramuscular as by the oral route.

Non-NASA Center↗

Transit Rider/Travel Behavior Inventory Survey - Minneapolis-St. Paul Metro - 2005

The survey was an on-board survey of transit riders on all regular route services for bus and light-rail in the Minneapolis-Saint Paul metropolitan area. The primary purpose of the study was to gather the data needed to update the mode choice models that are an integral component of the regional travel forecast model maintained by the Metropolitan Council, the metropolitan planning organization for the Minneapolis-Saint Paul metropolitan area. The survey instrument focused on identifying characteristics of the trip taken by each transit rider, including origin, destination, trip purpose, and mode of access. The survey also collected relevant socioeconomic and demographic information.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗