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At least 37 records · Page 2

Measurement and Reporting Guidelines for Solar Mirror Aging Tests Using Xenon Arc Lamp Exposure (XALE)

This technical report provides a guideline for accelerated aging tests on solar reflectors. Solar reflectors must have a high durability, with goal lifespans reaching 30 years. To test and develop state-of-the-art solar reflectors, relevant durability tests must be conducted. Existing guidelines for materials testing include isothermal testing, humidity testing, corrosion, etc., but many tests do not specify to include solar irradiance or address its relevance to solar reflector durability. The guideline focuses on test design and reporting guidelines for using Xenon Arc Lamp Exposure (XALE). The XALE environmental chambers can subject samples to a combination of relevant environmental factors including concentrated solar irradiance, heat, humidity, and weathering cycles. The guideline is meant to provide information on developing relevant test conditions, exposure times, reflectance characterization procedures, and data reporting.

14 SOLAR ENERGY↗

Hydrogen Sustainable Infrastructure Guidelines (H2SIG)

Infrastructure interacts with major global challenges inclusive of climate change, resilience, equity and social justice, environmental protection and biodiversity, public health, and economic recovery. This effort directly addresses how to apply sustainability assessments to the unique aspects of hydrogen (H2) infrastructure projects using the Envision® sustainability framework developed by the Institute for Sustainable Infrastructure (ISI). Envision is a flexible system of criteria and performance objectives to aid decision makers and help project teams identify sustainable approaches during planning, design and construction of infrastructure projects that will continue throughout the project’s operations, maintenance, and end-of-life phases. The goal of this work is to support those interested in conducting sustainability assessments for hydrogen infrastructure projects. Through this work the team has developed hydrogen-specific guidelines and best practices to assist project developers, investors and regulators in straightforward application of the Envision framework to systematically enhance clarity and increase objectivity across hydrogen projects. Subject matter experts from 20 different organizations (industry, non-profits, municipalities, emissions regulators, national labs) were engaged through 7 focus groups to discuss the H2-prioritized Envision requirements and elements to be included in the guidelines. In addition to these guidelines, the team conducted case studies as a way of demonstrating and informing the guidelines and providing examples or ideas for implementing sustainability in future projects. Through this study, the authors found that hydrogen infrastructure projects can incorporate many sustainable practices including reducing GHG emissions affecting climate change, reducing air pollutant emissions affecting the health of communities, synergistically handling waste byproducts, integrating into existing infrastructure, incorporating renewable energy, and addressing equity and environmental justice. Additionally, hydrogen infrastructure projects could benefit from 2-way communication engagement and collaborative planning with stakeholders, educational awareness of hydrogen technology, tracking and reporting on water use and water quality, and including monetized environmental and social benefits in life-cycle cost estimates. This document is the final technical report for the Hydrogen Sustainability Assessment Methods for Project Development project. While the main focus of the report is to provide guidelines for applying sustainability to hydrogen infrastructure, there are sections within the appendix providing completed project tasks and methodology.

08 HYDROGEN↗

Wind Turbine Design Guideline DG03: Yaw and Pitch Bearings

This design guideline describes the design criteria, calculation methods, and applicable standards recommended for use in performance and life analyses of ball and roller (rolling) bearings for yaw and pitch motion support in wind turbine applications. The formulae presented here for rolling bearing analytical methods and bearing-life ratings are consistent with methods currently used by wind turbine designers and rolling bearing manufacturers. The original yaw and pitch bearing design guideline was first drafted in 1999 by industry members and finally published in 2009 by the National Renewable Energy Laboratory. It was conceived as the third in a series of design guidelines, but it was the only one actually published by NREL and since has been known by the name "DG03." Other design guidelines were started, but instead of being published by NREL, they eventually became some of the International Electrotechnical Commission wind turbine standards in use today. This updated design guideline includes advances in research and field experiences made between 2009 and 2023. A better understanding of the operating conditions and damage mechanisms, advances in computational design, and publicly available test results facilitate more reliable yaw and pitch bearing designs.

17 WIND ENERGY↗

Safety in earth orbit study. Volume 4: Space shuttle orbiter: Safety requirements and guidelines on-orbit phase

Safety requirements and guidelines are listed for the space shuttle orbiter and for its interface with other vehicles. The requirements and guidelines are specific to the hazards and emergencies in earth orbit. The requirements and guidelines for the orbiter are those with respect to vehicle design, safety devices, warning devices, operational procedures, and residual hazards. The requirements and guidelines for interface with the space station, upper stage vehicles, and sortie payloads are imposed on these vehicles to ensure the safety of the shuttle orbiter. The rationale for the safety requirements and guidelines is also discussed.

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Phased Project Planning Guidelines

NHB 7121.2 is the initial publication of the guidelines for implementation of the Phased Project Planning (PPP) concept prescribed by NPD 7121,1A. These guidelines are applicable to the planning and approval activities which lead to the implementation of major new research and development projects as defined in NPD 7121.1A as well as to major modifications or extensions of approved projects. They should, therefore, be reflected in the Project Approval Documents which serve as the basic documentation for project definition, guidance and control throughout NASA. The purpose of PPP is to provide, through defined phases, an adequate basis for management decisions on the extent to which project activities can be properly undertaken and commitments made. However, these guidelines do not prescribe detailed format and content of plans and other documents and reports used to apply the PPP concept. Similarly, the work content of phases and the information requirements described herein are not checklists. They are included to assist in understanding the intent of the PPP concept and should not be viewed as rigid or inflexible. PPP, as a concept for orderly planning and definition of new major R&D undertakings, must be adapted to the peculiarities of each individual case. However, the flexibility permitted for adaptation should not be considered as a license for major variation which would compromise the objectives that underlie the concept. Cognizant NASA officials are expected to pursue their project planning and definition activities in reasonable conformance with these guidelines and to request only those exceptions or deviations which are clearly necessary and justified. These guidelines will be modified as determined necessary on the basis of experience. Comments or suggestions for changes should be directed to the Office of Organization and Management.

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Development of user guidelines for ECAS display design, volume 1

Experiment computer application software (ECAS) display design and command usage guidelines were developed, which if followed by spacelab experiments, would standardize methods and techniques for data presentation and commanding via ECAS. These guidelines would provide some commonality among experiments which would enhance crew training and flight operations. The guidelines are applicable to all onboard experiment displays, whether allocated by ECAS or a dedicated experiment processor. A brief description of the spacelab data display system characteristics and of the services provided by the experiment computer operating system is included. Guidelines concerning data presentation and layout of alphanumeric and graphic information are presented along with guidelines concerning keyboard commanding and command feedback.

Dodson, D. W.↗

High Voltage Design Guidelines: A Timely Update

The evolving state of high voltage systems and their increasing use in the space program have called for a revision of the High Voltage Design Guidelines, Marshall Space Flight Center technical document MSFC-STD-531, originally issued September 1978 (previously 50 M05189b, October 1972). These guidelines deal in depth with issues relating to the specification of materials, particularly electrical insulation, as well as design practices and test methods. Emphasis is on corona and Paschen breakdown as well as plasma effects for Low Earth Orbiting systems. We will briefly review the history of these guidelines as well as their immediate predecessors and discuss their range of applicability. In addition, this document has served as the basis for several derived works that became focused, program-specific HV guidelines. We will briefly review two examples, guidelines prepared for the X-33 program and for the Space Shuttle Electric Auxiliary Power Unit (EAPU) upgrade.

Hillard, G. Barry↗

New NASA SEE LEO Spacecraft Charging Design Guidelines: How to Survive in LEO Rather Than GEO

It has been almost two solar cycles since the 1984 GEO Guidelines of Purvis, Garrett, Whittlesey, and Stevens were published. In that time, interest in high voltage LEO systems has increased. Correct and conventional wisdom has been that LEO conditions are sufficiently different from GEO that the GEO Guidelines (and other GEO and POLAR documents produced since then) should not be used for LEO spacecraft. Because of significant recent GEO spacecraft failures that have been shown in ground testing to be likely to also occur on LEO spacecraft, the SEE program commissioned the production of the new LEO Spacecraft Charging Design Guidelines. Now available in CD-ROM form, the LEO Guidelines highlight mitigation techniques to prevent spacecraft arcing on LEO solar arrays and other systems. We compare and contrast the mitigation techniques for LEO and GEO in this paper. We also discuss the extensive bibliography included in the LEO Guidelines, so results can be found in their primary sources.

Ferguson, Dale C.↗

Modeling Guidelines for Code Generation in the Railway Signaling Context

Modeling guidelines constitute one of the fundamental cornerstones for Model Based Development. Their relevance is essential when dealing with code generation in the safety-critical domain. This article presents the experience of a railway signaling systems manufacturer on this issue. Introduction of Model-Based Development (MBD) and code generation in the industrial safety-critical sector created a crucial paradigm shift in the development process of dependable systems. While traditional software development focuses on the code, with MBD practices the focus shifts to model abstractions. The change has fundamental implications for safety-critical systems, which still need to guarantee a high degree of confidence also at code level. Usage of the Simulink/Stateflow platform for modeling, which is a de facto standard in control software development, does not ensure by itself production of high-quality dependable code. This issue has been addressed by companies through the definition of modeling rules imposing restrictions on the usage of design tools components, in order to enable production of qualified code. The MAAB Control Algorithm Modeling Guidelines (MathWorks Automotive Advisory Board)[3] is a well established set of publicly available rules for modeling with Simulink/Stateflow. This set of recommendations has been developed by a group of OEMs and suppliers of the automotive sector with the objective of enforcing and easing the usage of the MathWorks tools within the automotive industry. The guidelines have been published in 2001 and afterwords revisited in 2007 in order to integrate some additional rules developed by the Japanese division of MAAB [5]. The scope of the current edition of the guidelines ranges from model maintainability and readability to code generation issues. The rules are conceived as a reference baseline and therefore they need to be tailored to comply with the characteristics of each industrial context. Customization of these recommendations has been performed for the automotive control systems domain in order to enforce code generation [7]. The MAAB guidelines have been found profitable also in the aerospace/avionics sector [1] and they have been adopted by the MathWorks Aerospace Leadership Council (MALC). General Electric Transportation Systems (GETS) is a well known railway signaling systems manufacturer leading in Automatic Train Protection (ATP) systems technology. Inside an effort of adopting formal methods within its own development process, GETS decided to introduce system modeling by means of the MathWorks tools [2], and in 2008 chose to move to code generation. This article reports the experience performed by GETS in developing its own modeling standard through customizing the MAAB rules for the railway signaling domain and shows the result of this experience with a successful product development story.

Ferrari, Alessio↗

Spacecraft Water Exposure Guidelines for Selected Contaminants

The International Space Station is a closed and complex environment, so some contamination of its internal atmosphere and water system is expected. To protect space crews from contaminants in potable and hygiene water, the National Aeronautics and Space Administration (NASA) requested that the National Research Council (NRC) provide guidance on how to develop water exposure guidelines and review NASA s development of the exposure guidelines for specific chemicals. NASA selects water contaminants for which spacecraft water exposure guidelines (SWEGs) will be established; this involves identifying toxicity effects relevant to astronauts and calculating exposure concentrations on the basis of those end points. SWEGs are established for exposures of 1, 10, 100, and 1,000 days. This report is the second volume in the series, Spacecraft Water Exposure Guidelines for Selected Chemicals. SWEG reports for acetone, alkylamines, ammonia, barium, cadmium, caprolactam, formate, formaldehyde, manganese, total organic carbon, and zinc are included in this report. The committee concludes that the SWEGs developed for these chemicals are scientifically valid based on the data reviewed by NASA and are consistent with the NRC (2000) report, Methods for Developing Spacecraft Water Exposure Guidelines. SWEG reports for additional chemicals will be presented in a subsequent volume.

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Field Programmable Gate Array Failure Rate Estimation Guidelines for Launch Vehicle Fault Tree Models

Today's launch vehicles complex electronic and avionic systems heavily utilize the Field Programmable Gate Array (FPGA) integrated circuit (IC). FPGAs are prevalent ICs in communication protocols such as MIL-STD-1553B, and in control signal commands such as in solenoid/servo valves actuations. This paper will demonstrate guidelines to estimate FPGA failure rates for a launch vehicle, the guidelines will account for hardware, firmware, and radiation induced failures. The hardware contribution of the approach accounts for physical failures of the IC, FPGA memory and clock. The firmware portion will provide guidelines on the high level FPGA programming language and ways to account for software/code reliability growth. The radiation portion will provide guidelines on environment susceptibility as well as guidelines on tailoring other launch vehicle programs historical data to a specific launch vehicle.

Al Hassan, Mohammad↗

Automation & Autonomy Standards and Guidelines for Space Vehicles

The NASA Office of the Chief Health and Medical Officer (OCHMO) requested HRP conduct a survey of industry and government standards and guidelines for the interaction of automation/autonomy with humans. Guidance for verification testing of human-automation designs was also requested. A rapid response was requested so that the deliverables could be provided as part of a future NASA solicitation for automated systems for HLS. The project began with a broad review and analysis of prior NASA work in this area, as well as external standards related to human interaction with automation/autonomy. The team reviewed approximately 200 documents, and interviewed multiple industry and government subject matter experts (SMEs). “Gold standard” documents were selected for focus and key categories were identified. A cross-walk of standards was created, and common standards and guidelines were selected and rephrased (where necessary) to be information-rich, concise, and usable. Verification guidelines and examples were also developed. The final report includes an introduction to automation and autonomy, selected standards and guidelines, verification method guidance, and research gaps. In addition to the report, the team delivered a list of candidate standards for autonomous vehicles, as well as a list of candidate standards for a future NASA-STD-3001 update on automation/autonomy. The presentation will describe the rapid response project approach and methods, examples of standards and guidelines identified and delivered to OCHMO, and research needed to develop additional automation/autonomy design guidance where gaps currently exist.

automation↗

STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies

The interdisciplinary nature of microbiome research, coupled with the generation of complex multi-omics data, makes knowledge sharing challenging. The Strengthening the Organization and Reporting of Microbiome Studies (STORMS) guidelines provide a checklist for the reporting of study information, experimental design and analytical methods within a scientific manuscript on human microbiome research. Here, in this Consensus Statement, we present the standards for technical reporting in environmental and host-associated microbiome studies (STREAMS) guidelines. The guidelines expand on STORMS and include 67 items to support the reporting and review of environmental (for example, terrestrial, aquatic, atmospheric and engineered), synthetic and non-human host-associated microbiome studies in a standardized and machine-actionable manner. Based on input from 248 researchers spanning 28 countries, we provide detailed guidance, including comparisons with STORMS, and case studies that demonstrate the usage of the STREAMS guidelines. In conclusion, STREAMS, like STORMS, will be a living community resource updated by the Consortium with consensus-building input of the broader community.

59 BASIC BIOLOGICAL SCIENCES↗

Distributed Wind Certification Best Practices Guideline: January 16, 2023 - January 15, 2026

This Distributed Wind (DW) Certification Best Practices Guideline describes the typical approach for certification of distributed wind turbines above and below 150 kilowatts (kW) in size based on the conformity assessment requirements in the United States. The purpose of the guideline is to clarify and consistently describe the path to certification for various systems and components by helping the user navigate the complex path to certification compliance. This is done via clarification of both the required turbine type certification elements, as well as third-party electrical safety listing of turbine system components and subassemblies. In the United States specifically, there is no wind turbine certification scheme that governs or maintains a consistent set of conformity assessment requirements, and this can lead to wide ranging interpretations of the standards and required elements for certifications. This guideline attempts to simplify the path by organizing the information and guiding the user to the applicable set of requirements. Any wind turbine manufacturer or designer of wind turbines used in distributed generation applications in the United States would find value in the conformity assessment guidance in this guideline. Users are expected to be involved in the technical development of the product and supporting documentation, as the details provided are geared towards electrical and mechanical engineering of the system and components.

17 WIND ENERGY↗

Reviewing clinical considerations and guideline recommendations of C1 inhibitor prophylaxis for hereditary angioedema

Abstract Background Hereditary angioedema (HAE), a rare disease that is characterized by painful and recurring non‐allergic swelling episodes, is caused by the deficiency or dysfunction of C1 inhibitor (C1INH) protein. A comprehensive HAE management plan may require long‐term prophylaxis (LTP) in addition to on‐demand treatment to help “normalize” patients' lives so that they may fully engage in work, school, family, and leisure activities. Aim The main objective of this narrative review is to provide an overview of updated guideline recommendations specific to LTP of HAE and discuss clinical considerations and pharmacologic management options, with a focus on C1INH. Materials and Methods The authors reviewed relevant HAE literature for current recommendations regarding LTP and the role of C1NH. Results Acute HAE attacks are treated with on‐demand medication; however, there is a consensus that LTP should routinely be considered for risk reduction and prevention of future episodes. The 2017 World Allergy Organization/European Academy of Allergy and Clinical Immunology guidelines recommend that all patients with HAE be evaluated for LTP routinely and the 2020 HAE Association (HAEA) guidelines emphasize that the decision to use LTP should not be based on rigid criteria, but rather should be based on individual patient needs. Both guidelines recommend C1INH as first‐line/preferred therapy for LTP in a range of patient types including adults, children/adolescents, and pregnant/lactating patients. The HAEA also recommends the kallikrein inhibitor, lanadelumab, as a first‐line option for LTP. HAE pathway‐specific agents for LTP have not been associated with notable safety concerns. Discussion Plasma‐derived C1INH has been available for 40+ years in Europe and impacts multiple targets within the HAE pathway. C1INH has been used for on‐demand treatment and LTP. A subcutaneous formulation of plasma‐derived C1INH is approved for LTP and produces functional C1INH activity levels consistently above the threshold needed for protection from HAE attacks. Other pathway‐specific options for LTP include the plasma kallikrein inhibitors, lanadelumab‐flyo and berotralstat, approved for adults and pediatric patients aged ≥12 years. C1INH is approved for adults and pediatric patients aged ≥6 years. Conclusion Assessing the need for LTP is vital in the ongoing dialogue between clinicians and patients, as both disease‐related factors and patient preferences may change over time. Among available options for LTP, plasma‐derived C1INH is the broadly recommended first‐line option for LTP in patients with HAE, including pregnant/lactating women and pediatric patients (≥6 years).

Anderson, John↗

The Public Health Service guidelines. Governing research involving human subjects: An analysis of the policy-making process

The policy making process which led to development of the Public Health Service Guidelines governing research involving human subjects is outlined. Part 1 examines the evolution of PHS Guidelines, tracing (1) evolution of thought and legal interpretation regarding research using human subjects; (2) initial involvement of the Federal government; (3) development of the government's research program; (4) the social-political environment in which formal government policy was developed; and (5) various policy statements issued by the government. Part 2 analyzes the process by which PHS Guidelines were developed and examines the values and other underlying factors which contributed to their development. It was concluded that the evolution of the Guidelines is best understood within the context of a mixed-scanning strategy. In such a strategy, policy makers make fundamental decisions regarding the basic direction of policy and subsequent decisions are made incrementally and within the contexts set by the original fundamental decisions.

Frankel, M. S.↗

Manned space flight nuclear system safety. Volume 5: Nuclear System safety guidelines. Part 1: Space base nuclear safety

The design and operations guidelines and requirements developed in the study of space base nuclear system safety are presented. Guidelines and requirements are presented for the space base subsystems, nuclear hardware (reactor, isotope sources, dynamic generator equipment), experiments, interfacing vehicles, ground support systems, range safety and facilities. Cross indices and references are provided which relate guidelines to each other, and to substantiating data in other volumes. The guidelines are intended for the implementation of nuclear safety related design and operational considerations in future space programs.

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Manned space flight nuclear system safety. Voluem 5: Nuclear system safety guidelines. Part 2: Space shuttle/nuclear payloads safety

The design and operations guidelines and requirements developed in the study of space shuttle nuclear system transportation are presented. Guidelines and requirements are presented for the shuttle, nuclear payloads (reactor, isotope-Brayton and small isotope sources), ground support systems and facilities. Cross indices and references are provided which relate guidelines to each other, and to substantiating data in other volumes. The guidelines are intended for the implementation of nuclear safety related design and operational considerations in future space programs.

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