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At least 37 records · Page 2

Analysis of the classification of US and Canadian intensive test sites using the Image 100 hybrid classification system

The author has identified the following significant results. Labeling of wheat rather than total grains, particularly with only one acquisition, led to significant overestimates in some segments. The Image-100 software and procedures were written to facilitate classification of the LACIE segments but were not designed to record data for later accuracy assessment. A much better evaluation would have been possible if accuracy assessment data had been collected following each satisfactory classification.

Hocutt, W. T.↗

Computer-based classification accuracy due to the spatial resolution using per-point versus per-field classification techniques

Data sets simulating three different spatial resolutions (SR's) are computed from data with a 15-m nominal SR that were obtained with NASA's Thermatic Mapper Simulator from an altitude of about 6 km. The classification accuracies (CA's) achieved with the data of each of the four different SR's using a per-point Gaussian maximum likelihood classifier (GMLC) are intercompared. The CA's obtained using simulated 30-m SR data with the per-point GMLC are compared with the CA's achieved with a per-field classifier. It is found that: (1) the use of successively higher SR data resulted in lower overall CA's for classifications with the per-point GMLC, especially in cover classes associated with relatively higher spectral variability across adjacent pixels; (2) higher CA's were achieved using the per-field classifier with 30-m SR data than were achieved with the per-point GMLC; and (3) the largest increases in CA's were achieved with the per-field classifier in cover classes associated with relatively high levels of spectral variability across adjacent pixels.

Latty, R. S.↗

cTULIP: application of a human-based RNA-seq primary tumor classification tool for cross-species primary tumor classification in canine

The domestic dog, Canis familiaris, is quickly gaining traction as an advantageous model for use in the study of cancer, one of the leading causes of death worldwide. Naturally occurring canine cancers share clinical, histological, and molecular characteristics with the corresponding human diseases. In this study, we take a deep-learning approach to test how similar the gene expression profile of canine glioma and bladder cancer (BLCA) tumors are to the corresponding human tumors. We likewise develop a tool for identifying misclassified or outlier samples in large canine oncological datasets, analogous to that which was developed for human datasets. We test a number of machine learning algorithms and found that a convolutional neural network outperformed logistic regression and random forest approaches. We use a recently developed RNA-seq-based convolutional neural network, TULIP, to test the robustness of a human-data-trained primary tumor classification tool on cross-species primary tumor prediction. Our study ultimately highlights the molecular similarities between canine and human BLCA and glioma tumors, showing that protein-coding one-to-one homologs shared between humans and canines, are sufficient to distinguish between BLCA and gliomas. The results of this study indicate that using protein-coding one-to-one homologs as the features in the input layer of TULIP performs good primary tumor prediction in both humans and canines. Furthermore, our analysis shows that our selected features also contain the majority of features with known clinical relevance in BLCA and gliomas. Our success in using a human-data-trained model for cross-species primary tumor prediction also sheds light on the conservation of oncological pathways in humans and canines, further underscoring the importance of the canine model system in the study of human disease.

60 APPLIED LIFE SCIENCES↗

Compressive Classification for TEM-EELS

Acquiring atomic-resolution images of beam sensitive materials or under dynamic conditions (e.g. operando STEM) is very difficult and requires precise dose fractioning to minimize the dose delivered to the sample and acquire the data more rapidly than dynamics present. Typical methods of low-dose STEM imaging include adjusting the beam current, dwell-time, and probe Scanning transmission electron microscopy (STEM) is used routinely to obtain atomic-resolution images of a small selection of radiation tolerant materials under stable conditions.size. All three of these determine the dose over a spatial area in STEM. Recently, compressive sensing [1] has been applied to electron microscopy. The computational imaging method of inpainting [2] has been proposed as a method to reduce dose and increase acquisition speed for STEM. Inpainting is a technique to recover missing pixels in an image. By skipping pixels (randomly) during acquisition, a fourth dose-control mechanism is realized [3]. A few implementations of randomly-subsampled STEM exist (e.g., [4]). To make the concepts of compressive sensing accessible to the microscopy community we begin with an example using atomic resolution images of a GaAs crystal (see Figure 1). Because the crystal is periodic it has a sparse representation in reciprocal space. In fact, a sparse representation is a key component of compressive sensing. If an image is sub-sampled randomly we find that the Fourier transform remains sparse, but becomes increasing noisy as less and less data is acquired. Yet, by finding the peaks in the reciprocal image and removing the noise it is possible to recover atomic resolution images with only 1% of the pixels. Figure 1 shows the reconstruction process for GaAs sub-sampled at 50%, 10%, 5%, and 1%. Periodic images form a special class for which the optimal sampling approach (according to CS theory) is a random selection of pixels. For non-periodic images, such as those arising in in-situ STEM, methods such as dictionary learning are necessary [2,5]. The data can be compressed in time for TEM [5] or pixels can be skipped randomly for STEM. There are several issues that arise in developing a random scan for STEM [4] and a coded aperture for TEM. The remainder of the talk will address these issues. References: [1] E Candes and M Wakin. Signal Processing Magazine, IEEE. 2(25) (2008), pp. 21. [2] A Stevens, Pu Y, Sun Y, et al. Artificial Intelligence & Statistics (AISTATS), 2017. [3] A Stevens, H Yang, L Carin et al. Microscopy 63(1), (2014), pp. 41. [4] L Kovarik, A Stevens, A Liyu et al. Appl. Phys. Lett. 109, 164102 (2016). [5] A Stevens, L Kovarik, P Abellan et al. Adv. Structural and Chemical Imaging 1(10), (2015), pp. 1. [6] Supported by the Chemical Imaging, Signature Discovery, and Analytics in Motion Initiatives at PNNL. PNNL is operated by Battelle Memorial Inst. for the US DOE; contract DE-AC05-76RL01830.

Hao, Weituo↗

SCOPe: classification of large macromolecular structures in the structural classification of proteins—extended database

The SCOPe (Structural Classification of Proteins—extended, https://scop.berkeley.edu) database hierarchically classifies domains from the majority of proteins of known structure according to their structural and evolutionary relationships. SCOPe also incorporates and updates the ASTRAL compendium, which provides multiple databases and tools to aid in the analysis of the sequences and structures of proteins classified in SCOPe. Protein structures are classified using a combination of manual curation and highly precise automated methods. In the current release of SCOPe, 2.07, we have focused our manual curation efforts on larger protein structures, including the spliceosome, proteasome and RNA polymerase I, as well as many other Pfam families that had not previously been classified. Domains from these large protein complexes are distinctive in several ways: novel non-globular folds are more common, and domains from previously observed protein families often have N- or C-terminal extensions that were disordered or not present in previous structures. The current monthly release update, SCOPe 2.07–2018-10–18, classifies 90 992 PDB entries (about two thirds of PDB entries).

Biochemistry & Molecular Biology↗

Pyrotechnic hazards classification and evaluation program. Phase 3, segments 1-4: Investigation of sensitivity test methods and procedures for pyrotechnic hazards evaluation and classification, part A

The findings, conclusions, and recommendations relative to the investigations conducted to evaluate tests for classifying pyrotechnic materials and end items as to their hazard potential are presented. Information required to establish an applicable means of determining the potential hazards of pyrotechnics is described. Hazard evaluations are based on the peak overpressure or impulse resulting from the explosion as a function of distance from the source. Other hazard classification tests include dust ignition sensitivity, impact ignition sensitivity, spark ignition sensitivity, and differential thermal analysis.

Source record↗

Classification of multispectral image data by extraction and classification of homogeneous objects

A method of classification of digitized multispectral image data is described. It is designed to exploit a particular type of dependence between adjacent states of nature that is characteristic of the data. The advantages of this, as opposed to the conventional per point approach, are greater accuracy and efficiency, and the results are in a more desirable form for most purposes. Experimental results from both aircraft and satellite data are included.

Kettig, R. L.↗

Land use classification for hydrologic models using interactive machine classification of LANDSAT data

Models designed to simulate the hydrology of urban areas require input parameters describing the land use and degree of imperviousness of the watershed. Unfortunately, the magnitude and spatial distribution of these parameters are rather difficult to estimate when a large watershed is involved. Trade-offs between accuracy of the model parameters and the time or money available for their determination must be made. Because of the necessity of such trade-offs, a study was developed to investigate the use of computer aided analysis of LANDSAT multispectral data in estimating percent of imperviousness and associated land uses needed in urban hydrologic modeling. An interactive computer was used to delineate seven land use classifications in the 342 sq. km. Maryland portion of the Anacostia River Basin from LANDSAT data. These results compared favorably with those of an earlier study which obtained the same information through analysis of aerial photographs having a scale of 1:4800. Approximately 94 man days were required to complete the land use analysis using the aerial photographs while less than three man days were required to accomplish similar tasks using the LANDSAT data.

Thomas J. Jackson↗

Classification of multispectral image data by extraction and classification of homogeneous objects

A classification method for digitized multispectral-image data is described. This method is designed to exploit a particular type of dependence between adjacent states of nature that is characteristic of the data. The advantages of this, as opposed to the conventional 'per point' approach, are greater accuracy and efficiency, and the results are in a more desirable form for most purposes. Experimental results from both aircraft and satellite data are included.

Kettig, R. L.↗

Gaussian maximum likelihood and contextual classification algorithms for multicrop classification

The paper reviews some of the ways in which context has been handled in the remote-sensing literature, and additional possibilities are introduced. The problem of computing exhaustive and normalized class-membership probabilities from the likelihoods provided by the Gaussian maximum likelihood classifier (to be used as initial probability estimates to start relaxation) is discussed. An efficient implementation of probabilistic relaxation is proposed, suiting the needs of actual remote-sensing applications. A modified fuzzy-relaxation algorithm using generalized operations between fuzzy sets is presented. Combined use of the two relaxation algorithms is proposed to exploit context in multispectral classification of remotely sensed data. Results on both one artificially created image and one MSS data set are reported.

Di Zenzo, Silvano↗

Gaussian maximum likelihood and contextual classification algorithms for multicrop classification experiments using thematic mapper and multispectral scanner sensor data

The paper presents the results of a four-factor two-level analysis of a variance experiment designed to evaluate the combined effect of the improved quality of remote-sensor data and the use of context by the classifier on classification accuracy. The improvement achievable by using the context via relaxation techniques is significantly smaller than that provided by an increase of the radiometric resolution of the sensor from 6 to 8 bits per sample (the relative increase in radiometric resolution of TM relative to MSS). It is almost equal to that achievable by an increase in the spectral coverage as provided by TM relative to MSS.

Di Zenzo, Silvano↗

End-to-End Physics Event Classification with CMS Open Data: Applying Image-Based Deep Learning to Detector Data for the Direct Classification of Collision Events at the LHC

This paper describes the construction of novel end-to-end image-based classifiers that directly leverage low-level simulated detector data to discriminate signal and background processes in pp collision events at the Large Hadron Collider at CERN. To better understand what end-to-end classifiers are capable of learning from the data and to address a number of associated challenges, we distinguish the decay of the standard model Higgs boson into two photons from its leading background sources using high-fidelity simulated CMS Open Data. We demonstrate the ability of end-to-end classifiers to learn from the angular distribution of the photons recorded as electromagnetic showers, their intrinsic shapes, and the energy of their constituent hits, even when the underlying particles are not fully resolved, delivering a clear advantage in such cases over purely kinematics-based classifiers.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Quasar classification using color and variability

We conduct a pilot investigation to determine the optimal combination of color and variability information to identify quasars in current and future multi-epoch optical surveys. We use a Bayesian quasar selection algorithm to identify 35,820 type 1 quasar candidates in a 239 deg{sup 2} field of the Sloan Digital Sky Survey (SDSS) Stripe 82, using a combination of optical photometry and variability. Color analysis is performed on 5-band single- and multi-epoch SDSS optical photometry to a depth of r∼22.4. From these data, variability parameters are calculated by fitting the structure function of each object in each band with a power-law model using 10 to >100 observations over timescales from ∼1 day to ∼8 years. Selection was based on a training sample of 13,221 spectroscopically confirmed type-1 quasars, largely from the SDSS. Using variability alone, colors alone, and combining variability and colors we achieve 91%, 93%, and 97% quasar completeness and 98%, 98%, and 97% efficiency, respectively, with particular improvement in the selection of quasars at 2.7<z<3.5 where quasars and stars have similar optical colors. The 22,867 quasar candidates that are not spectroscopically confirmed reach a depth of i∼22.0; 21,876 (95.7%) are dimmer than coadded i-band magnitude of 19.9, the cutoff for spectroscopic follow-up for SDSS on Stripe 82. Brighter than 19.9, we find 5.7% more quasar candidates without confirming spectra in sky regions otherwise considered complete. The resulting quasar sample has sufficient purity (and statistically correctable incompleteness) to produce a luminosity function comparable to those determined by spectroscopic investigations. We discuss improvements that can be made to the process in preparation for performing similar photometric selection and science on data from post-SDSS sky surveys.

79 ASTRONOMY AND ASTROPHYSICS↗

Radiation Anomaly Detection and Classification with Bayes Model Selection

We present a new method for radiation anomaly detection that is based on Bayes Model Selection (BMS), together with models for gamma-radiation measurements from benign and threat sources. The method estimates the relative odds of pairs of such models, with the aim of supporting related hypotheses about the nature of the underlying source material. We also discuss partial optimization of the parameters in the models. The method allows measurements to be broadly categorized and screened for sources of interest in real time, a property that should improve the efficiency of mobile search or unattended monitoring operations.

Anomaly detection, Gamma-ray spectroscopy, Radiati↗

DeepLearnMOR: a deep-learning framework for fluorescence image-based classification of organelle morphology

Abstract The proper biogenesis, morphogenesis, and dynamics of subcellular organelles are essential to their metabolic functions. Conventional techniques for identifying, classifying, and quantifying abnormalities in organelle morphology are largely manual and time-consuming, and require specific expertise. Deep learning has the potential to revolutionize image-based screens by greatly improving their scope, speed, and efficiency. Here, we used transfer learning and a convolutional neural network (CNN) to analyze over 47,000 confocal microscopy images from Arabidopsis wild-type and mutant plants with abnormal division of one of three essential energy organelles: chloroplasts, mitochondria, or peroxisomes. We have built a deep-learning framework, DeepLearnMOR (Deep Learning of the Morphology of Organelles), which can rapidly classify image categories and identify abnormalities in organelle morphology with over 97% accuracy. Feature visualization analysis identified important features used by the CNN to predict morphological abnormalities, and visual clues helped to better understand the decision-making process, thereby validating the reliability and interpretability of the neural network. This framework establishes a foundation for future larger-scale research with broader scopes and greater data set diversity and heterogeneity.

Plant Sciences↗