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All sourcesNASA NTRSDOE OSTI
NASA NTRS2001

Cyclic strain increases protease-activated receptor-1 expression in vascular smooth muscle cells

Cyclic strain regulates many vascular smooth muscle cell (VSMC) functions through changing gene expression. This study investigated the effects of cyclic strain on protease-activated receptor-1 (PAR-1) expression in VSMCs and the possible signaling pathways involved, on the basis of the hypothesis that cyclic strain would enhance PAR-1 expression, reflecting increased thrombin activity. Uniaxial cyclic strain (1 Hz, 20%) of cells cultured on elastic membranes induced a 2-fold increase in both PAR-1 mRNA and protein levels. Functional activity of PAR-1, as assessed by cell proliferation in response to thrombin, was also increased by cyclic strain. In addition, treatment of cells with antioxidants or an NADPH oxidase inhibitor blocked strain-induced PAR-1 expression. Preincubation of cells with protein kinase inhibitors (staurosporine or Ro 31-8220) enhanced strain-increased PAR-1 expression, whereas inhibitors of NO synthase, tyrosine kinase, and mitogen-activated protein kinases had no effect. Cyclic strain in the presence of basic fibroblast growth factor induced PAR-1 mRNA levels beyond the effect of cyclic strain alone, whereas no additive effect was observed between cyclic strain and platelet-derived growth factor-AB. Our findings that cyclic strain upregulates PAR-1 mRNA expression but that shear stress downregulates this gene in VSMCs provide an opportunity to elucidate signaling differences by which VSMCs respond to different mechanical forces.

NASA Discipline Cell Biology↗
NASA NTRS2000

Progress in the Development of a Class of Efficient Low Dissipative High Order Shock-capturing Methods

In a series of papers, Olsson (1994, 1995), Olsson & Oliger (1994), Strand (1994), Gerritsen Olsson (1996), Yee et al. (1999a,b, 2000) and Sandham & Yee (2000), the issue of nonlinear stability of the compressible Euler and Navier-Stokes Equations, including physical boundaries, and the corresponding development of the discrete analogue of nonlinear stable high order schemes, including boundary schemes, were developed, extended and evaluated for various fluid flows. High order here refers to spatial schemes that are essentially fourth-order or higher away from shock and shear regions. The objective of this paper is to give an overview of the progress of the low dissipative high order shock-capturing schemes proposed by Yee et al. (1999a,b, 2000). This class of schemes consists of simple non-dissipative high order compact or non-compact central spatial differencings and adaptive nonlinear numerical dissipation operators to minimize the use of numerical dissipation. The amount of numerical dissipation is further minimized by applying the scheme to the entropy splitting form of the inviscid flux derivatives, and by rewriting the viscous terms to minimize odd-even decoupling before the application of the central scheme (Sandham & Yee). The efficiency and accuracy of these scheme are compared with spectral, TVD and fifth- order WENO schemes. A new approach of Sjogreen & Yee (2000) utilizing non-orthogonal multi-resolution wavelet basis functions as sensors to dynamically determine the appropriate amount of numerical dissipation to be added to the non-dissipative high order spatial scheme at each grid point will be discussed. Numerical experiments of long time integration of smooth flows, shock-turbulence interactions, direct numerical simulations of a 3-D compressible turbulent plane channel flow, and various mixing layer problems indicate that these schemes are especially suitable for practical complex problems in nonlinear aeroacoustics, rotorcraft dynamics, direct numerical simulation or large eddy simulation of compressible turbulent flows at various speeds including high-speed shock-turbulence interactions, and general long time wave propagation problems. These schemes, including entropy splitting, have also been extended to freestream preserving schemes on curvilinear moving grids for a thermally perfect gas (Vinokur & Yee 2000).

Yee, H. C.↗
NASA NTRS1984

On long-term periodicities in the sunspot record

Sunspot records are systematically maintained, with the knowledge that an 11 year average period exists since about 1850. Thus, the sunspot record of highest quality and considered to be the most reliable is that of cycle eight through the present. On the basis of cycles 8 through 20, various combinations of sine curves were used to approximate the observed R sub MAX values (where R sub MAX is the smoothed sunspot number at cycle maximum). It is found that a three component sinusoidal function, having an 11 cycle and a 2 cycle variation on a 90 cycle periodicity, yields computed R sub MAX values which fit, reasonably well, observed R sub MAX values for the modern sunspot cycles. Extrapolation of the empirical functions forward in time allows for the projection of values of R sub MAX for cycles 21 and 22. For cycle 21, the function projects a value of 157.3, very close to the actually observed value of 164.5. For cycle 22, the function projects a value of about 107. Linear regressions applied to cycle 22 indicate a long-period cycle (cycle duration 132 months). An extensive bibliography on techniques used to estimate the time dependent behavior of sunspot cycles is provided.

Wilson, R. M.↗
NASA NTRS1993

Transition operators in electromagnetic-wave diffraction theory. II - Applications to optics

The theory developed by Hahne (1992) for the diffraction of time-harmonic electromagnetic waves from fixed obstacles is briefly summarized and extended. Applications of the theory are considered which comprise, first, a spherical harmonic expansion of the so-called radiation impedance operator in the theory, for a spherical surface, and second, a reconsideration of familiar short-wavelength approximation from the new standpoint, including a derivation of the so-called physical optics method on the basis of quasi-planar approximation to the radiation impedance operator, augmented by the method of stationary phase. The latter includes a rederivation of the geometrical optics approximation for the complete Green's function for the electromagnetic field in the presence of a smooth- and a convex-surfaced perfectly electrically conductive obstacle.

Hahne, G. E.↗
NASA NTRS1972

Spline smoothing of histograms by linear programming

An algorithm for an approximating function to the frequency distribution is obtained from a sample of size n. To obtain the approximating function a histogram is made from the data. Next, Euclidean space approximations to the graph of the histogram using central B-splines as basis elements are obtained by linear programming. The approximating function has area one and is nonnegative.

Bennett, J. O.↗
NASA NTRS1988

Full configuration-interaction study of the ionic-neutral curve crossing in LiF

Full configuration-interaction (FCI) calculations are used to assess the relative ability of methods for truncating the n-particle expansion in describing the ionic-neutral curve crossing between the two lowest Sigma(+) states of LiF. While the FCI calculations yield a smooth dipole moment function, MRCI calculations based on CASSCF orbitals optimized for the lowest state at all r values yield a discontinuous dipole moment function. However, when the orbitals are optimized using a state-averaged CASSCF procedure, with equal weights for the ionic and neutral solutions, both the CASSCF and MRCI dipole moment functions are smooth and in reasonable agreement with the FCI. No single-reference-based method is found to work satisfactorily. Potential curves for the lowest two Sigma(+) states are determined in both the adiabatic and diabatic representations using a large atomic natural orbit Gaussian basis set and a state-averaged CASSCF/MRCI treatment of electron correlation.

Bauschlicher, Charles W., Jr.↗
NASA NTRS1991

A search for periodicity in the x ray spectrum of black hole candidate A0620-00

The archived data from the SAS-3 observations of the X-ray nova A0620-00, the best of the stellar blackhole candidates, were exhaustively examined for evidence of variable phenomena correlated with the orbital motion of the binary system of which it is a member. The original analysis of these data was completed before discovery of the binary companion and determination of the orbital period of the system. New interest was drawn to the task of a reexamination of the archive data by the recent discovery of the massive nature of the X-ray source through analysis of the Doppler variations and ellipsoidal light variations of the faint K-star companion by McClintock and Remillard. The archive research, carried out under the supervision of the principal investigator, was the topic of the thesis submitted to the MIT Department of Physics by Kenneth Plaks in partial fulfillment of the requirements for the degree of Master of Science. Plaks' effort was focused on the elimination of fluctuations in the data due to errors in attitude solutions and other extraneous causes. The first products of his work were long-term light curves of the X-ray intensities in the various energy channels as functions of time during the time from outbursts in August 1975 to quiescence approximately 6 months later. These curves, are refined versions of the preliminary results published in 1976 (Matilsky et al. 1976). Smooth exponentials were fitted to these long term light curves to provide the basis for detrending the data, thereby permitting a calculation of residuals derived by subtracting the fitted curve from the data. The residuals were then analyzed by Fourier analysis to search for variations with the period of the binary orbit, namely 7.75 hours. No evidence of an orbital periodicity was found. However, the refined light curve provides a much clearer picture of the outburst and subsequent decay of the X-ray luminosity. In fact, there were two outbursts, each followed by an exponential decay with similar time constants of about 25 days. Previous evidence of a three-oscillation variation with a 7.8 day period were confirmed. Substantial theoretical effort has been devoted to attempts to account for the decay characteristics as the result of the gradual eating up of an accretion disk by a stellar-mass blackhole (e.g., Huang and Wheeler 1989). The improved decay curves will provide significant new constraints on the theoretical analyses.

Clark, George W.↗
NASA NTRS1977

The lifetime of ice particles in the solar system

The behavior of spherical water-ice particles in interplanetary space is investigated theoretically using an equation which gives the sublimation rate as a function of the solar energy distribution at 1 AU, solar distance, the temperature of the ice-particle surface, the temperature of the surrounding background, particle absorption efficiency, particle radius, and the complex refractive index of ice. The variation of sublimation rate with particle size is examined, and it is shown that the sublimation rate depends critically on the absorptivity of ice in the near-IR spectral region. Two different spectral-absorption curves are plotted on the basis of two different choices for the complex refractive index of ice, and an attempt is made to decide experimentally which energy distribution is more appropriate. Results of direct laboratory measurements of the sublimation rate of smooth spherical ice particles are compared with the theoretical results obtained from the cited sublimation-rate equation. Agreement between theory and experiment is found to be excellent when the complex refractive indices given by Bertie et al., (1969) are employed. Sublimation rates and particle lifetimes are then computed as a function of particle radius for heliocentric distances of 0.5, 0.75, and 1.0 AU.

Patashnick, H.↗
NASA NTRS1981

New approach to the solution of large, full matrix equations

A new approach to the solution of matrix equations resulting from integral equations is presented and applied to the solution of two-dimensional Neumann problems describing the inviscid, incompressible flow past an airfoil. The problem is reformulated in terms of a preselected set of mode functions giving an equivalent matrix equation to be solved for the mode-function expansion coefficients. Because of the inherent smoothness of the original problem, the coefficient problem can be solved approximately without significantly affecting the accuracy of the final solution. Very promising two-dimensional results are obtained and the extension of the method to three-dimensional problems is investigated. On the basis of these results it is shown that the computing time for the matrix solution for a large three-dimensional panel method calculation could be reduced by an order of magnitude compared with that required for a direct solution.

Clark, R. W.↗
NASA NTRS2003

Development of Numerical Codes for Modeling Electromagnetic Behavior at High Frequencies Near Large Objects

A study into the problem of determining electromagnetic solutions at high frequencies for problems involving complex geometries, large sizes and multiple sources (e.g. antennas) has been initiated. Typical applications include the behavior of antennas (and radiators) installed on complex conducting structures (e.g. ships, aircrafts, etc..) with strong interactions between antennas, the radiation patterns, and electromagnetic signals is of great interest for electromagnetic compatibility control. This includes the overall performance evaluation and control of all on-board radiating systems, electromagnetic interference, and personnel radiation hazards. Electromagnetic computational capability exists at NASA LaRC, and many of the codes developed are based on the Moment Method (MM). However, the MM is computationally intensive, and this places a limit on the size of objects and structures that can be modeled. Here, two approaches are proposed: (i) a current-based hybrid scheme that combines the MM with Physical optics, and (ii) an Alternating Direction Implicit-Finite Difference Time Domain (ADI-FDTD) method. The essence of a hybrid technique is to split the overall scattering surface(s) into two regions: (a) a MM zone (MMZ) which can be used over any part of the given geometry, but is most essential over irregular and "non-smooth" geometries, and (b) a PO sub-region (POSR). Currents induced on the scattering and reflecting surfaces can then be computed in two ways depending on whether the region belonged to the MMZ or was part of the POSR. For the MMZ, the current calculations proceed in terms of basis functions with undetermined coefficients (as in the usual MM method), and the answer obtained by solving a system of linear equations. Over the POSR, conduction is obtained as a superposition of two contributions: (i) currents due to the incident magnetic field, and (ii) currents produced by the mutual induction from conduction within the MMZ. This effectively leads to a reduction in the size of linear equations from N to N - Npo with N being the total number of segments for the entire surface and Npo the number of segments over the POSR. The scheme would be appropriate for relatively large, flat surfaces, and at high frequencies. The ADI-FDTD scheme provides for both transient and steady state analyses. The restrictive Courant-Friedrich-Levy (CFL) condition on the time-step is removed, and so large time steps can be chosen even though the spatial grids are small. This report includes the problem definition, a detailed discussion of both the numerical techniques, and numerical implementations for simple surface geometries. Numerical solutions have been derived for a few simple situations.

Joshi, R. P.↗
NASA NTRS1984

Nonunique solutions to the transonic potential flow equation

Steinhoff and Jameson (1981) have shown that within a certain range of angle of attack and freestream Mach number, numerical solutions of the full-potential equation for flow past an airfoil are not unique. This study was mainly concerned with showing that the anomaly is inherent to the partial-differential equation governing the flow and not a result of its discrete representation. Steinhoff and Jameson conjectured that the anomaly may have a physical basis. The present investigation has two objectives. Results are to be presented which indicate that the anomaly is due to a breakdown in the potential approximation, rather than a phenomenon associated with the inviscid flowfield. The second objective is to show that the lift coefficient, predicted by the potential equation, is a smooth but multivalued function of the angle of attack.

Salas, M. D.↗
NASA NTRS1979

A new approach to the solution of large, full matrix equations: A two-dimensional potential flow feasibility study

An approach to the solution of matrix problems resulting from integral equations of mathematical physics is presented. Based on the inherent smoothness in such equations, the problem is reformulated using a set of orthogonal basis vectors, leading to an equivalent coefficient problem which can be of lower order without significantly impairing the accuracy of the solution. This approach was evaluated using a two-dimensional Neumann problem describing the inviscid, incompressible flow over an airfoil. Two different kinds of mode functions were investigated, namely eigenfunction series and Fourier series. The method using Fourier series was found preferable. It uses all of the coefficients from a Fast Fourier Transform algorithm in an approximate method which exploits the known structure of the transformed coefficient matrix and very promising results for the flow over a realistic airfoil are obtained. On the basis of the results presented here, an order of magnitude reduction in this computer time can be expected for such problems as compared with the time for a direct matrix solution.

James, R. M.↗
NASA NTRS1984

A comparative look at sunspot cycles

On the basis of cycles 8 through 20, spanning about 143 years, observations of sunspot number, smoothed sunspot number, and their temporal properties were used to compute means, standard deviations, ranges, and frequency of occurrence histograms for a number of sunspot cycle parameters. The resultant schematic sunspot cycle was contrasted with the mean sunspot cycle, obtained by averaging smoothed sunspot number as a function of time, tying all cycles (8 through 20) to their minimum occurence date. A relatively good approximation of the time variation of smoothed sunspot number for a given cycle is possible if sunspot cycles are regarded in terms of being either HIGH- or LOW-R(MAX) cycles or LONG- or SHORT-PERIOD cycles, especially the latter. Linear regression analyses were performed comparing late cycle parameters with early cycle parameters and solar cycle number. The early occurring cycle parameters can be used to estimate later occurring cycle parameters with relatively good success, based on cycle 21 as an example. The sunspot cycle record clearly shows that the trend for both R(MIN) and R(MAX) was toward decreasing value between cycles 8 through 14 and toward increasing value between cycles 14 through 20. Linear regression equations were also obtained for several measures of solar activity.

Wilson, R. M.↗
NASA NTRS1978

Galactic plane gamma radiation

Analysis of the complete data from SAS-2 accentuates the fact that the distribution of galactic gamma radiation has several similarities to that of other large-scale tracers of galactic structure. The gamma radiation shows no statistically significant variation with direction, and the spectrum seen along the plane is the same as that derived for the galactic component of the gamma radiation at high latitude. This uniformity of the energy spectrum, the smooth decrease in intensity as a function of galactic latitude, and the absence of any galactic gamma ray sources at high latitudes argue in favor of a diffuse origin for most of the galactic gamma radiation, rather than a collection of localized sources. All the localized sources identified in the SAS 2 data are associated with known compact objects on the basis of observed periodicities, except gamma195+5 Excluding those SAS 2 sources observed by COS-B and two other excesses (CG 312-1 and CG333+0) visible in the SAS 2 data associated with tangential directions of spiral arms, thera are eight remaining new sources in the COS-B catalog.

Hartman, R. C.↗
NASA NTRS1986

Numerical simulation of boundary layers. Part 1: Weak formulation and numerical method

A numerical method designed to solve the time-dependent, three-dimensional, incompressible Navier-Stokes equations in boundary layers is presented. The fluid domain is the half-space over a flat plate, and periodic conditions are applied in the horizontal directions. The discretization is spectral. The basis functions are divergence-free and a weak formulation of the momentum equation is used, which eliminates the pressure term. An exponential mapping and Jacobi polynomials are used in the semi-infinite direction, with the irrotational component receiving special treatment. Issues related to the accuracy, stability and efficiency of the method are discussed. Very fast convergence is demonstrated on some model problems with smooth solutions. The method has also been shown to accurately resolve the fine scales of transitional and turbulent boundary layers.

Spalart, P. R.↗
NASA NTRS1984

Objective scatterometer wind ambiguity removal using smoothness and dynamical constraints

In the present investigation, a variational analysis method (VAM) is used to remove the ambiguity of the Seasat-A Satellite Scatterometer (SASS) winds. At each SASS data point, two, three, or four wind vectors (termed ambiguities) are retrieved. It is pointed out that the VAM is basically a least squares method for fitting data. The problem may be nonlinear. The best fit to the data and constraints is obtained on the basis of a minimization of the objective function. The VAM was tested and tuned at 12 h GMT Sept. 10, 1978. Attention is given to a case study involving an intense cyclone centered south of Japan at 138 deg E.

Hoffman, R. N.↗
NASA NTRS2016

The XXL Survey I. Scientific Motivations - Xmm-Newton Observing Plan - Follow-up Observations and Simulation Programme

The quest for the cosmological parameters that describe our universe continues to motivate the scientific community to undertake very large survey initiatives across the electromagnetic spectrum. Over the past two decades, the Chandra and XMM-Newton observatories have supported numerous studies of X-ray-selected clusters of galaxies, active galactic nuclei (AGNs), and the X-ray background. The present paper is the first in a series reporting results of the XXL-XMM survey; it comes at a time when the Planck mission results are being finalized. Aims. We present the XXL Survey, the largest XMM programme totaling some 6.9 Ms to date and involving an international consortium of roughly 100 members. The XXL Survey covers two extragalactic areas of 25 deg2 each at a point-source sensitivity of approx. 5 x 10(exp 15) erg/s/sq cm in the [0.5-2] keV band (completeness limit). The surveys main goals are to provide constraints on the dark energy equation of state from the space-time-distribution of clusters of galaxies and to serve as a pathfinder for future, wide-area X-ray missions. We review science objectives, including cluster studies, AGN evolution, and large-scale structure, that are being conducted with the support of approximately 30 follow-up programs. Methods. We describe the 542 XMM observations along with the associated multi- and numerical simulation programmes. We give a detailed account of the X-ray processing steps and describe innovative tools being developed for the cosmological analysis. Results. The paper provides a thorough evaluation of the X-ray data, including quality controls, photon statistics, exposure and background maps, and sky coverage. Source catalogue construction and multi-associations are briefly described. This material will be the basis for the calculation of the cluster and AGN selection functions, critical elements of the cosmological and science analyses. Conclusions. The XXL multi- data set will have a unique lasting legacy value for cosmological and extragalactic studies and will serve asa calibration resource for future dark energy studies with clusters and other X-ray selected sources. With the present article, we release the XMM XXL photon and smoothed images along with the corresponding exposure maps.

X-rays: general – large-scale structure of Unive↗
NASA NTRSDate not supplied

Advances in Estimation of the Earth Orientation Parameters From Observation

Historically, a two-step procedure for estimation of Universal Time and polar motion from observations was adopted: night averages from individual observatories formed a raw non-equidistant time series that was edited for outliers, smoothed, and formed the final data product. This approach was by inertia used for processing modern space geodesy observations. I will present an alternative one-step approach and its application for processing a dataset of VLBI observations since 1990.0 through present. The essence of this approach is to represent the Earth orientation parameters in a form of an expansion into basic functions and estimate of the expansion coefficients directly from observations. A further extension of this approach is to assimilate not only space geodesy data, but atmospheric and ocean angular momentum from assimilation numerical weather models and their forecasts. That makes a smooth bridge between Earth rotation estimation and prediction. I will talk about my experience of running data analysis in such a way on a semi-operational basis, present results, and discuss advantages and disadvantages of this approach.

Leonid Petrov↗