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All sourcesNASA NTRSDOE OSTI
DOE OSTI2024

The Influence of the Number of Tree Searches on Maximum Likelihood Inference in Phylogenomics

Maximum likelihood (ML) phylogenetic inference is widely used in phylogenomics. As heuristic searches most likely find suboptimal trees, it is recommended to conduct multiple (e.g., 10) tree searches in phylogenetic analyses. However, beyond its positive role, how and to what extent multiple tree searches aid ML phylogenetic inference remains poorly explored. Here, we found that a random starting tree was not as effective as the BioNJ and parsimony starting trees in inferring the ML gene tree and that RAxML-NG and PhyML were less sensitive to different starting trees than IQ-TREE. We then examined the effect of the number of tree searches on ML tree inference with IQ-TREE and RAxML-NG, by running 100 tree searches on 19,414 gene alignments from 15 animal, plant, and fungal phylogenomic datasets. We found that the number of tree searches substantially impacted the recovery of the best-of-100 ML gene tree topology among 100 searches for a given ML program. In addition, all of the concatenation-based trees were topologically identical if the number of tree searches was ≥10. Quartet-based ASTRAL trees inferred from 1 to 80 tree searches differed topologically from those inferred from 100 tree searches for 6/15 phylogenomic datasets. Lastly, our simulations showed that gene alignments with lower difficulty scores had a higher chance of finding the best-of-100 gene tree topology and were more likely to yield the correct trees.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2023

Differentiable Neural Architecture, Mixed Precision and Accelerator Co-Search

Quantization, effective Neural Network architecture, and efficient accelerator hardware are three important design paradigms to maximize accuracy and efficiency. Mixed Precision Quantization is a process of assigning different precision to different Neural Network layers for optimized inference. Neural Architecture Search (NAS) is a process of automatically designing the neural network for a task and can also be extended to search for the precision of each weight and activation matrix. In this paper, we develop the following three methods: (i) Fast Differentiable Hardware-aware Mixed Precision Quantization Search method to find optimal precision, (ii) Joint Differentiable hardware-aware Architecture and Mixed Precision Quantization Co-search, (iii) Joint Accelerator, Architecture, and Precision triple co-search to find best possibilities in all the three worlds. We demonstrate the effectiveness of our proposed methods targeting Bitfusion accelerator by searching mixed precision models on MobilenetV2. We achieve better accuracy-latency trade-off models than the manually designed and previously proposed search methods.

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2024

A First Search for Argon-Bound Neutron-Antineutron Oscillation using the MicroBooNE LArTPC

The use of Liquid Argon Time Projection Chambers (LArTPCs) as a detector technology in neutrino experiments has grown considerably over the past two decades. The excellent spatial and calorimetric resolution offered by LArTPCs enable precise neutrino oscillation measurements as well as beyond-Standard Model searches. One such search, which is the focus of this note, is the search for nucleus-bound neutron-antineutron (n ₋ n̄) oscillation. The n ₋ n̄ oscillation process is a baryon number violating process that produces a unique, star-like topology as a result of multiple final state pions. This unique signature is a key feature that may be used to search for this signal process. This note describes a machine learning-based analysis of MicroBooNE data, making use of a sparse convolutional neural network to search for n ₋ n̄ oscillation-like signals in MicroBooNE. While the future DUNE LArTPC can search for this signature with high sensitivity, existing MicroBooNE data can be used to demonstrate and validate methodologies that can be used as part of the DUNE search. This document presents the first-ever search for n ₋ n̄ oscillation in a LArTPC, using MicroBooNE off-beam data (data collected when the neutrino beam was not running).

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2024

A first search for argon-bound neutron-antineutron oscillation using the MicroBooNE LArTPC

The use of Liquid Argon Time Projection Chambers (LArTPCs) as a detector technology in neutrino experiments has grown considerably over the past two decades. The excellent spatial and calorimetric resolution offered by LArTPCs enable precise neutrino oscillation measurements as well as beyond-Standard Model searches. One such search, which is the focus of this note, is the search for nucleus-bound neutron-antineutron (n – n̄) oscillation. The n – n̄ oscillation process is a baryon number violating process that produces a unique, star-like topology as a result of multiple final state pions. This unique signature is a key feature that may be used to search for this signal process. This note describes a machine learning-based analysis of MicroBooNE data, making use of a sparse convolutional neural network to search for n – n̄ oscillation-like signals in MicroBooNE. While the future DUNE LArTPC can search for this signature with high sensitivity, existing MicroBooNE data can be used to demonstrate and validate methodologies that can be used as part of the DUNE search. This document presents the first-ever search for n – n̄ oscillation in a LArTPC, using MicroBooNE off-beam data (data collected when the neutrino beam was not running).

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2024

Search for New Physics with the Compact Muon Solenoid Experiment and QIS-enabled Technology

Understanding the fundamental nature of dark matter (DM)---its cosmological origin, constituents, and interactions---is one of the most important questions in fundamental science today. In this thesis, I present two novel and highly complementary approaches to cover the gaps in sensitivity of current DM searches. The searches are enabled by a first-of-its-kind reconstruction technique to search for hidden-sector particles using the Compact Muon Solenoid (CMS) and by new advances in quantum sensing technology to search for axions and hidden-sector DM. In the first part of this thesis, I present a search for long-lived hidden sector particles, predicted by many extensions of the SM, using a novel technique to reconstruct decays of long-lived particles (LLPs) in the CMS muon detector. The innovative LLP reconstruction technique is sensitive to a broad range of LLP decays and to LLP masses below GeV. The search yields competitive sensitivity for proper lifetime 0.1--1000 m with the full Run 2 dataset recorded at the LHC between 2016--2018 at $\sqrt{s} = 13~$TeV. To extend the physics reach of this novel muon detector shower (MDS) signature, I present the model-independence of MDS and the reinterpretation of the search to a large number of LLP models, demonstrating its complementarity with proposed and existing dedicated LLP experiments. Finally, I present a new dedicated MDS trigger that improves the trigger efficiency by at least an order of magnitude and was deployed in 2022, at the start of Run 3 of the LHC operations. In the second part of the thesis, I present for the first time, the use of a novel quantum sensor, the low-noise and single-photon sensitive superconducting nanowire single photon detectors (SNSPDs), to directly detect dark matter. The low detection threshold and ultra-low dark count rate of SNSPDs can close the gap in DM discovery reach due to the current limitations in detector sensitivity. I will present my work on the development and characterization of SNSPDs for two entirely new experiments to directly detect axions via absorption and hidden-sector DM via electron scattering. The search for axions employs a novel broadband reflector technique with the Broadband Reflector Experiment for Axion Detection (BREAD). A unique parabolic mirror is then used to focus axion-converted photons to the SNSPDs, extending the reach to axion masses of 0.04--1 eV. On the other hand, by coupling the SNSPDs with gallium arsenide, a bright cryogenic scintillator well matched to SNSPD detection, a prototype sensing system can be built as a basis of new direct DM detection experiments capable of extending the discovery to DM masses as low as 1 MeV.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2022

Search for Lepton Flavor Violation in Two Body Muon and Pion Decay at Rest

The ability of the Mu2e experiment to probe, or discover beyond the Standard Model physics in direct Charged Lepton Flavor Violation $\mu^+$ and $\pi^+$ decay modes is estimated. These direct modes are searched for simultaneously with proposed Mu2e detector validation runs, and are complementary to the Mu2e main search goal, an indirect search for $\mu^- \to e^-$ conversion at the sensitivity level of $\sim 10^{-17}$. The $\mu^+$ validation run will operate at 50% nominal magnetic field and reduced proton beam intensity to less than 1/100th nominal, in order to observe the e+ spectrum from $\mu^+$ decay, at and below the Michel edge Ee . 53 MeV. The $\pi^+$ validation run, based on measuring the mono-energetic e+ emission in the decay $\pi^+ \to e+\nu$, at 76% of nominal magnetic field and reduced beam intensity less than 1/5th nominal. Both of these runs can be used to fix the momentum scale for the Mu2e conversion search. In addition the muon validation dataset can be used to correct for systematic errors in the detector response by mapping the well known to O(\u03B13) corrected theoretical Michel spectrum, to the observed spectrum. One direct search is for two-body Charged Lepton Flavor Violation $\mu^+ \to e^+X$ decay, where $X$ is a light new physics particle. This allows Mu2e to explore well motivated models including axion like particles with flavor violating couplings and massive $Z^0$ bosons with more sensitivity then present astrophysical and laboratory constraints. In two weeks of data-taking, Mu2e can achieve direct mode 90% confidence level branching ratio limits of $10^{-7}$ over the mass range $20 \le m_X \le 50$ MeV, improving the current experimental limit at $10^{-5}$ by two orders of magnitude. In the mass range $m_X \le 20$ MeV, assuming systematic error corrections can be made by correcting the Monte Carlo mapping, the achievable search sensitivity is found to be $2.3\times 10^{-7}$ for $m_X =0$, an order of magnitude improvement over the current best limit at $2.6\times 10^{-6}$, when assuming $V+A$ or isotropic coupling. The $\pi^+$ validation run, allows searching for $\pi^+ \to e^+N$ decay, where $N$ is a heavy neutral lepton such as a heavy sterile neutrino, in the mass region $20 \le m_N \le 65$ MeV. A branching ratio limit at 90% confidence level of $3\times 10^{-8}$ can be achieved in two weeks, an improvement of the current search sensitivity limit by an order of magnitude.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2024

Searches for Higgs boson production through decays of heavy resonances

The discovery of the Higgs boson has led to new possible signatures for heavy resonance searches at the LHC. Since then, search channels including at least one Higgs boson plus another particle have formed an important part of the program of new physics searches. In this report, the status of these searches by the CMS Collaboration is reviewed. Searches are discussed for resonances decaying to two Higgs bosons, a Higgs and a vector boson, or a Higgs boson and another new resonance. All analyses use proton–proton collision data collected at $\sqrt{s} = 13$ TeV in the years 2016–2018. A combination of the results of these searches is presented together with constraints on different beyond-the-standard model scenarios, including scenarios with extended Higgs sectors, heavy vector bosons and extra dimensions. Studies are shown for the first time by CMS on the validity of the narrow-width approximation in searches for the resonant production of a pair of Higgs bosons. The potential for a discovery at the High Luminosity LHC is also discussed.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2026

RCSB protein data Bank: Next‐generation advanced search for exploration of experimental structures and computed structure models

Abstract The Protein Data Bank (PDB), established in 1971, is the primary global, open‐access archive for experimentally determined 3D macromolecular structures (proteins, RNA, DNA). The research‐focused RCSB.org web‐portal provides access to these data alongside more than one million machine‐learning‐predicted structure models, greatly expanding the available structural landscape. Rapid growth of both experimental and computational structures has increased the need for powerful yet accessible search tools that serve a broad and diverse scientific community. Herein, we describe a redesigned RCSB Protein Data Bank RCSB.org Advanced Search capability that supports intuitive discovery of 3D structures through a unified interface. This interface integrates annotation‐, sequence‐, and 3D structure‐based searches, embeds an interactive 3D viewer, and incorporates curated biological knowledge, such as catalytic site definitions from Mechanism and Catalytic Site Atlas and ligand‐guided structural motifs, for constructing geometry‐driven queries. A new Chemical Search tool allows definition of chemical queries via an integrated drawing tool or standard identifiers, seamlessly combining them with annotation filters. By allowing query definition directly within spatial and chemical contexts, these search interfaces reduce the need for detailed knowledge of residue numbering, chain identifiers, or external cheminformatics software. This capability enables efficient exploration of structures, chemical diversity, and structure–function relationships across all life domains. The redesigned interfaces can be accessed directly at rcsb.org/search/advanced for Advanced Search and rcsb.org/search/chemical for Chemical Search.

Rose, Yana [Research Collaboratory for Structural ↗
DOE OSTI2025

Mechanical sensors for ultraheavy dark matter searches via long-range forces

Dark matter candidates with masses around the Planck scale are theoretically well-motivated, and it has been suggested that it might be possible to search for dark matter solely via gravitational interactions in this mass range. In this work, we explore the pathway towards searching for dark matter candidates with masses around the Planck scale using mechanical sensors while considering realistic experimental constraints, and develop analysis techniques needed to conduct such searches. These dark matter particles are expected to leave tracks as their signature in mechanical sensor arrays, and we show that we can effectively search for such tracks using statistical approaches to track-finding. We analyze a range of possible experimental setups and compute sensitivity projections for searches for ultraheavy dark matter coupling to the Standard Model via long-range forces. We find that while a search for Planck-scale dark matter purely via gravitational couplings would be exceedingly difficult, requiring ∼80 dB of quantum noise reduction with a 100 3 array of devices, there is a wide range of currently unexplored dark matter candidates which can be searched for with already existing or near-term experimental platforms.

Qin, Juehang [Rice Univ., Houston, TX (United Stat↗
DOE OSTI2021

Optimizing FPGA-based Accelerator Design for Large-Scale Molecular Similarity Search (Special Session Paper)

Molecular similarity search has been widely used in drug discovery to rapidly identify structurally similar compounds from large molecular databases. With the increasing size of chemical libraries, there is growing interest in the efficient ac- celeration of large-scale similarity search. Existing works mainly focus on CPU and GPU to accelerate the computation of Tatimoto coefficient in measuring the pairwise similarity between different molecular fingerprints. In this paper, we propose and optimize an FPGA-based accelerator design on exhaustive and approximate search algorithms. On exhaustive search using BitBound & fold- ing, we analyze the similarity cutoff and folding level relationship with search speedup and accuracy, and propose a scalable on- the-fly query engine on FPGAs to reduce the resource utilization and pipeline interval. We achieve a 450 million compounds-per- second processing throughput for a single query engine. On approximate search using hierarchical navigable small world (HNSW), a popular algorithm with high recall and query speed, we propose an FPGA-based graph traversal engine to utilize high throughput register array based priority queue and fine- grained distance calculation engine to increase the processing capability. Experimental results show that the proposed FPGA- based HNSW implementation achieves a 35× speedup than existing works on CPU. To the best of our knowledge, our FPGA- based implementation is the first attempt to accelerate molecular similarity search on FPGA and has the highest performance among existing approaches.

Peng, Hongwu↗
DOE OSTI2021

An Indirect Search for Weakly Interacting Massive Particles in the Sun Using Upward-going Muons in NOvA

I present the first Dark Matter search results using the full data set collected with the upward-going muon trigger in NOvA. Weakly Interactive Massive Particles (WIMPs) are a theoretical non-baryonic form of Dark Matter. The nature of Dark Matter is one of the most exciting open questions in modern physics. Though its existence can be inferred by astrophysical evidence, its properties are not yet understood. If we assume that Dark Matter particles can produce Standard Model particles through their interactions, an indirect search can help shed light on this mystery.The NOvA collaboration has built a 14 kton, fine-grained, low-Z, total absorption tracking calorimeter at an off-axis angle to the NuMI neutrino beam. Even though the detector is optimized to observe electron neutrino appearance from a muon neutrino beam, it has a unique potential for more exotic searches given its excellent granularity and energy resolution and relatively low-energy neutrino thresholds. In fact, with an efficient upward-going muon trigger and sufficient background suppression offline, NOvA is capable of a competitive indirect Dark Matter search for low-mass WIMPs.The idea of the upward-going muon trigger is first to select high-quality muon tracks, then use the timing information of all of the hits of each track to estimate directionality. In this way, the background flux is suppressed by more than a factor of 10^5 at trigger level to a rate of approximately 1 Hz. To further optimize this search, we use only upward-going muons that point to the Sun, so our search occurs at night when the Sun is on the other side of the Earth. This strategy also allows us to use the time when the Sun is above the horizon as a control region to estimate the background. Ultimately, implementation of a cut based and maximum likelihood analysis provides a powerful tool for rejecting background and selecting a sample of neutrino-induced upward-going muons. The overall background rejection power achieved by the analysis is substantial and impressive. Starting with approximately 150,000 events per second, we reduced it to 40 events per year. Since no statistically significant excess was found, a 90\% C.L. upper limit on the expected muon flux of upward-going muons has been set using the upper limit on the number of events given the number of observed events in the signal region. Lastly, by assuming the theory behind the upward-going muon flux, a limit on the WIMP-nucleon spin-dependent cross-section in the Sun was estimated. Although the limits on the spin-dependent cross-section do not appear to be competitive with previous indirect Dark Matter searches, the upward-going muon flux limits are promising. The upward-going muon flux limits could extend these results to a broader class of models that are not specific to the dark matter theory but produce upward-going muons, leading to competitive results.

Principato, Cristiana↗
DOE OSTI2021

Searching for Interstellar Quantum Communications

The modern search for extraterrestrial intelligence began with the seminal publications of Cocconi & Morrison and Schwartz & Townes, who proposed searching for narrowband signals in the radio spectrum and optical laser pulses. Over the last six decades, more than 100 dedicated search programs have targeted these wavelengths, all with null results. All of these campaigns searched for classical communications, that is, for a significant number of photons above a noise threshold, with the assumption of a pattern encoded in time and/or frequency space. I argue that future searches should also target quantum communications. They are preferred over classical communications with regard to security and information efficiency, and they would have escaped detection in all previous searches. The measurement of Fock state photons or squeezed light would indicate the artificiality of a signal. I show that quantum coherence is feasible over interstellar distances and explain for the first time how astronomers can search for quantum transmissions sent by ETI to Earth using commercially available telescopes and receiver equipment.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2021

Searching for Dwarf Galaxies in Gaia DR2 Phase-space Data Using Wavelet Transforms

We present a wavelet-based algorithm to identify dwarf galaxies in the Milky Way in Gaia DR2 data. Our algorithm detects overdensities in 4D position–proper-motion space, making it the first search to explicitly use velocity information to search for dwarf galaxy candidates. We optimize our algorithm and quantify its performance by searching for mock dwarfs injected into Gaia DR2 data and for known Milky Way satellite galaxies. Comparing our results with previous photometric searches, we find that our search is sensitive to undiscovered systems at Galactic latitudes |b| > 20° and with half-light radii larger than the 50% detection efficiency threshold for Pan-STARRS1 (PS1) at (i) absolute magnitudes of –7 < M V < –3 and distances of 32 kpc < D < 64 kpc, and (ii) M V < –4 and 64 kpc < D < 128 kpc. Based on these results, we predict that our search is expected to discover 5 ± 2 new satellite galaxies: four in the PS1 footprint and one outside the Dark Energy Survey and PS1 footprints. We apply our algorithm to the Gaia DR2 data set and recover ~830 high-significance candidates, out of which we identify a "gold standard" list of ~200 candidates based on cross-matching with potential candidates identified in a preliminary search using Gaia EDR3 data. All of our candidate lists are publicly distributed for future follow-up studies. Here, we show that improvements in astrometric measurements provided by Gaia EDR3 increase the sensitivity of this technique; we plan to continue to refine our candidate list using future data releases.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2024

A Targeted Search for Variable Gravitationally Lensed Quasars

We present a pipeline to identify photometric variability within strong gravitationally lensing candidates, in the Dark Energy Spectroscopic Instrument Legacy Imaging Surveys. In our first paper, we laid out our pipeline and presented seven new gravitationally lensed supernovae candidates in a retrospective search. In this companion paper, we apply a modified version of that pipeline to search for gravitationally lensed quasars. From a sample of 5807 strong lenses, we have identified 13 new gravitationally lensed quasar candidates (three of them quadruply lensed). We note that our methodology differs from most lensed quasar search algorithms that solely rely on the morphology, location, and color of the candidate systems. By also accounting for the temporal photometric variability of the posited lensed images in our search via difference imaging, we have discovered new lensed quasar candidates. While variability searches using difference imaging algorithms have been done in the past, they are typically performed over vast swathes of the sky, whereas we specifically target strong gravitationally lensed candidates. We also have applied our pipeline to 655 known gravitationally lensed quasar candidates from past lensed quasar searches, of which we identified 13 that display significant variability (one of them quadruply lensed). This pipeline demonstrates a promising search strategy to discover gravitationally lensed quasars in other existing and upcoming surveys.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2025

Data release for A search for extremely-high-energy neutrinos and first constraints on the ultra-high-energy cosmic-ray proton fraction with IceCube

<h1 id="summary">Summary</h1> <p>Title: Data Release for A search for extremely-high-energy neutrinos and first constraints on the ultra-high-energy cosmic-ray proton fraction with IceCube</p> <p>The IceCube observatory analyzed 12.6 years of data in search of extremely-high-energy (EHE) neutrinos above 5 PeV. The resultant limit of the search (Fig 1), and the effective area of the event selection (Fig 7), are provided in this data release.</p> <h1 id="contents">Contents</h1> <ul> <li><p>README file: this file</p> </li> <li><p><code>differential_limit_and_sensitivity.csv</code>: a comma separated value file, giving the observed experimental differential limit, and sensitivity, of the search as a function of neutrino energy. This is the content of Fig 1 in the paper. The first column is the neutrino energy in GeV. The second column is the limit in units of GeV/cm2/s/sr. The third column is the sensitivity in units of GeV/cm2/s/sr.</p> </li> <li><p><code>effective_area.csv</code>: a comma separated value file, giving the effective area of the search as a function of energy. This is the content of Fig 7 in the paper. The first column is the neutrino energy in GeV. The second column is the total effective area of the search, summed across neutrino flavors, and averaged across neutrinos and antineutrinos, in meters-squared. The third column is the effective area of the search for the average of electron neutrino and electron antineutrinos in units of meters-squared. The fourth column is the same as the third, but for muon-flavor neutrinos. The fifth column is the same as the third and fourth, but for tau-flavor neutrinos.</p> </li> <li><p><code>demo.py</code>: a short python script to demonstrate how to read the files. Run like <code>python demo.py</code>. A standard base python installation is sufficient, as the only dependencies are numpy and matplotlib.</p> </li> </ul> <h1 id="contacts">Contacts</h1> <p>For any questions about this data release, please write to analysis@icecube.wisc.edu</p>

Astronomy and Astrophysics↗
DOE OSTI2023

A Search for Pulsars around Sgr A* in the First Event Horizon Telescope Data Set

In 2017 the Event Horizon Telescope (EHT) observed the supermassive black hole at the center of the Milky Way, Sagittarius A* (Sgr A*), at a frequency of 228.1 GHz (λ = 1.3 mm). The fundamental physics tests that even a single pulsar orbiting Sgr A* would enable motivate searching for pulsars in EHT data sets. The high observing frequency means that pulsars—which typically exhibit steep emission spectra—are expected to be very faint. However, it also negates pulse scattering, an effect that could hinder pulsar detections in the Galactic center. Additionally, magnetars or a secondary inverse Compton emission could be stronger at millimeter wavelengths than at lower frequencies. We present a search for pulsars close to Sgr A* using the data from the three most sensitive stations in the EHT 2017 campaign: the Atacama Large Millimeter/submillimeter Array, the Large Millimeter Telescope, and the IRAM 30 m Telescope. We apply three detection methods based on Fourier-domain analysis, the fast folding algorithm, and single-pulse searches targeting both pulsars and burst-like transient emission. We use the simultaneity of the observations to confirm potential candidates. No new pulsars or significant bursts were found. Being the first pulsar search ever carried out at such high radio frequencies, we detail our analysis methods and give a detailed estimation of the sensitivity of the search. We conclude that the EHT 2017 observations are only sensitive to a small fraction (≲2.2%) of the pulsars that may exist close to Sgr A*, motivating further searches for fainter pulsars in the region.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2025

Charged Higgs search in 2HDM

In this paper, we present a comprehensive study of the collider search limits on the charged Higgses in the four types of Two Higgs Double Models (2HDM). In addition to constraints from flavor physics measurements, we include both the LEP charged Higgs search channels, as well as the LHC search results on the light and heavy charged Higgses. We consider both the conventional charged Higgs search channels of H ± → τν, cs, cb, tb, and the latest search results on the exotic decay channels H ± → AW ± /HW ± . We find that H ± → AW ± /HW ± are complementary to the conventional fermionic channels for m H ± < m t . For heavy H ± , H ± → AW ± /HW ± extend the reach of tan β beyond that of H ± → tb in the Type-L 2HDM. We also present the combined reach of all the neutral and charged Higgs searches.

2HDM↗
DOE OSTI2026

Search for the nonresonant and resonant production of a Higgs boson in association with an additional scalar boson in the $γγττ$ final state in proton-proton collisions at $\sqrt{s}=13$ TeV

The results of a search for the production of two scalar bosons in final states with two photons and two tau leptons are presented. The search considers both nonresonant production of a Higgs boson pair, HH, and resonant production via a new boson X which decays either to HH or to H and a new scalar Y. The analysis uses up to 138 fb −1 of proton-proton collision data, recorded between 2016 and 2018 by the CMS experiment at the LHC at a center-of-mass energy of 13 TeV. No evidence for signal is found in the data. For the nonresonant production, the observed (expected) upper limit at 95% confidence level (CL) on the HH production cross section is set at 930 (740) fb, corresponding to 33 (26) times the standard model prediction. At 95% CL, HH production is observed (expected) to be excluded for values of κ λ outside the range between −12 (−9.4) and 17 (15). Observed (expected) upper limits at 95% CL for the X → HH cross section are found to be within 160 to 2200 (200 to 1800) fb, depending on the mass of X. In the X → Y(ττ)H(γγ) search, the observed (expected) upper limits on the product of the production cross section and decay branching fractions vary between 0.059–1.2 fb (0.087–0.68 fb). For the X → Y(γγ)H(ττ) search the observed (expected) upper limits on the product of the production cross section and Y → γγ branching fraction vary between 0.69–15 fb (0.73–8.3 fb) in the low Y mass search, tightening constraints on the next-to-minimal supersymmetric standard model, and between 0.64–10 fb (0.70–7.6 fb) in the high Y mass search.

Beyond Standard Model↗