Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “Scientific Workflows”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 37 records · Page 2

A Review of Extra-Terrestrial Regolith Excavation Concepts and Prototype

Regolith is present on many extra-terrestrial bodies, and the crushed rock material it is made of contains many of the resources that are enabling for In-Situ Resource Utilization (ISRU). When extracted, these resources can be used to provide consumables such as rocket propellant, human life support, working fluids and gases for industrial processes and feedstocks for manufacturing. In addition, the regolith can also be very beneficial for construction purposes as an aggregate which can be used for construction materials and shielding for radiation protection and micrometeorite impact. Binders for regolith concrete may also be made from geopolymers that may be in the regolith. The regolith can be melted and drawn out into glass fibers and used as reinforcements in a metal, polymer, or concrete matrix. In addition, there is tremendous scientific and geological knowledge that can only be obtained by studying samples of the regolith. However, none of these valuable activities can proceed without first acquiring the regolith granular material with some type of excavation device and method. Excavation is in the critical path of many workflows that will make up the capabilities required to establish a human and robotic presence in our solar system. While scientific in-situ sampling of regolith in small quantities has been achieved since the dawn of the space age in the 1960’s, large scale excavation for mining and construction on extra-terrestrial bodies has only been contemplated, for many decades, but serious development and prototyping of excavation technologies for use in reduced gravity space environments was only started in the late 1990’s. This paper will review and document the evolution of extra-terrestrial excavation concepts and prototypes based on the available literature and the personal experience of the author who has been working on regolith excavation technology development since 1998.

Regolith↗

Analytical Needs in a Sample Receiving Facility: Input from the MSR Operation Definition Team

The return of scientifically selected samples from Mars would provide a rare opportunity forinvestigation with the full range of the latest technology available, but to take full advantageof this opportunity, it is important to plan ahead to ensure the pristine nature of the samplesupon arrival within the Earth environment until scientific investigations can begin.The NASA/ESA science community-driven MSR Science Planning Group – Phase 2 (MSPG2)delivered recommendations and guidance regarding curation (1) and science (2, 3) activities tobe performed on the samples under containment. High-level requirements for the infrastruc-ture were also developed by MSPG2 (4). In order to prepare infrastructure-targeted input forthe ESA and NASA facility studies planned in the 2022-2023 timeframe, the agency-led MSROperational Scenarios Definition Team (MOSDT) was assembled to conceptualize the sampleoperations that will inform future architecture teams. Emphasis was placed on the respon-sibility of MOSDT to use community-defined requirements and to represent the view of the international scientific community.All necessary and sufficient instruments and analytical needs described in MSPG2 were inte-grated in MOSDT main deliverable, the operational workflow (see Hays et al, this conference).In MSPG2, notional instruments were split between curation analytical needs, and objective-driven (time-sensitive and sterilization-sensitive) science analytical needs. In MOSDT, whilethe first phases of curation, “pre-Basic Characterization” and “Basic Characterization” wererather streamlined and separate from other analytical needs, “Preliminary Examination” and“Science” instruments were not always physically segregated. In addition to the necessary andsufficient instruments described by MSPG2, the MOSDT recommended additional supportequipment for sterilization, cleanliness and contamination monitoring.It was sometimes necessary for the MOSDT to rely on assumptions to integrate instruments inthe activity workflow. In general, the assumptions were very conservative to limit contaminationand cross-contamination risks. It is expected that future work to refine limits of contaminationwill enable optimization of instrumentation.The community was consulted during the course of the MOSDT work. This abstract’s aimis two-fold: on one hand, inform the scientific community and overall MSR stakeholders, tobring their attention on the analytical needs currently considered as necessary and sufficient;on the other hand, to solicit feedback from a larger community audience to optimize and refineanalytical needs during the next phases of MSR ground-segment preparation.Disclaimer: The decision to implement Mars Sample Return will not be finalized until NASA’scompletion of the program’s National Environmental Policy Act (NEPA) process. This docu-ment is being made available for informational purposes only.[1] Tait et al. (2021) Preliminary planning for Mars Sample Return (MSR) curation activities ina Sample Receiving Facility (SRF). Astrobiology in press, doi:10.1089/ast.2021.0105. [2] Toscaet al. (2021) Time-sensitive aspects of Mars Sample Return (MSR) science. Astrobiologyin press, doi:10.1089/ast.2021.0115. [3] Velbel et al. (2021) Planning implications relatedto sterilization-sensitive science investigations associated with Mars Sample Return (MSR).Astrobiology in press, doi:10.1089/ast.2021.0113. [4] Carrier et al. (2021) Science and curationconsiderations for the design of a Mars Sample Return (MSR) Sample Receiving Facility (SRF).Astrobiology in press, doi:10.1089/ast.2021.0110.

Mars Sample Return↗

Distinguishing Provenance Equivalence of Earth Science Data

Reproducibility of scientific research relies on accurate and precise citation of data and the provenance of that data. Earth science data are often the result of applying complex data transformation and analysis workflows to vast quantities of data. Provenance information of data processing is used for a variety of purposes, including understanding the process and auditing as well as reproducibility. Certain provenance information is essential for producing scientifically equivalent data. Capturing and representing that provenance information and assigning identifiers suitable for precisely distinguishing data granules and datasets is needed for accurate comparisons. This paper discusses scientific equivalence and essential provenance for scientific reproducibility. We use the example of an operational earth science data processing system to illustrate the application of the technique of cascading digital signatures or hash chains to precisely identify sets of granules and as provenance equivalence identifiers to distinguish data made in an an equivalent manner.

Tilmes, Curt↗

Maximizing Spaceflight Biological Data with Omics Analytics: The NASA GeneLab Database

NASA’s GeneLab includes an open-access repository of some 250+ omics datasets generated by biological experiments relevant to spaceflight including simulated cosmic radiation and microgravity. In order to maximize the intelligibility of these data, particularly for users with limited bioinformatics background, GeneLab has become a knowledgebase platform converting raw genetic and proteomic signatures found in flight samples into biological and physiological meanings. A large community of more than 100 scientists has rallied behind GeneLab and organized into four Analysis Working Groups (AWGs: Animal, Plant, Microbe, and Multi-Omics). Together, the AWGs have gained scientific recognition worldwide by establishing a consortium in charge of adopting new complex standards for data analysis workflows and omics sample processing in a rapidly evolving field. We will demonstrate the usage of the repository with smart search capability, an online controlled-access toolshed "Galaxy" to process user data with vetted standard workflows, a workspace for data sharing and a data submission portal with ontology control for better metadata curation. The GeneLab visualization portal will also be demonstrated, showing how anyone without formal training in bioinformatics can now browse the space biology omics data to discover new biology and potential solutions to improve life in space.

Sylvain Vincent Costes↗

GeneLab: The NASA System Biology Platform for Space Omics Repository, Analysis and Visualization

NASA’s GeneLab includes an open-access repository of some 250+ omics datasets generated by biological experiments relevant to spaceflight including simulated cosmic radiation and microgravity. In order to maximize the intelligibility of these data, particularly for users with limited bioinformatics background, GeneLab has become a knowledgebase platform converting raw genetic and proteomic signatures found in flight samples into biological and physiological meanings. A large community of more than 100 scientists has rallied behind GeneLab and organized into four Analysis Working Groups (AWGs: Animal, Plant, Microbe, and Multi-Omics). Together, the AWGs have gained scientific recognition worldwide by establishing a consortium in charge of adopting new complex standards for data analysis workflows and omics sample processing in a rapidly evolving field. We will demonstrate the usage of the repository with smart search capability, an online controlled-access toolshed "Galaxy" to process user data with vetted standard workflows, a workspace for data sharing and a data submission portal with ontology control for better metadata curation. The GeneLab visualization portal will also be demonstrated, showing how anyone without formal training in bioinformatics can now browse the space biology omics data to discover new biology and potential solutions to improve life in space.

GeneLab↗

Simplifying NASA Earth Science Data and Information Access Through Natural Language Processing Based Data Analysis and Visualization

NASA Earth science data collected from satellites, model assimilation, airborne missions, and field campaigns, are large, complex and evolving. Such characteristics pose great challenges for end users (e.g., Earth science and applied science users, students, citizen scientists), particularly for those who are unfamiliar with NASA's EOSDIS and thus unable to access and utilize datasets effectively. For example, a novice user may simply ask: what is the total rainfall for a flooding event in my county yesterday? For an experienced user (e.g., algorithm developer), a question can be: how did my rainfall product perform, compared to ground observations, during a flooding event? Nonetheless, with rapid information technology development such as natural language processing, it is possible to develop simplified Web interfaces and back-end processing components to handle such questions and deliver answers in terms of text, data, or graphic results directly to users.In this presentation, we describe the main challenges for end users with different levels of expertise in accessing and utilizing NASA Earth science data. Surveys reveal that most non-professional users normally do not want to download and handle raw data as well as conduct heavy-duty data processing tasks. Often they just want some simple graphics or data for various purposes. To them, simple and intuitive user interfaces are sufficient because complicated ones can be difficult and time-consuming to learn. Professionals also want such interfaces to answer many questions from datasets. One solution is to develop a natural language based search box like Google and the search results can be text, data, graphics and more. Now the challenge is, with natural language processing, can we design a system to process a scientific question typed in by a user? In this presentation, we describe our plan for such a prototype. The workflow is: 1) extract needed information (e.g., variables, spatial and temporal information, processing methods, etc.) from the input, 2) process the data in the backend, and 3) deliver the results (data or graphics) to the user.

Liu, Zhong↗

The SunPy Project: An Interoperable Ecosystem for Solar Data Analysis

The SunPy Project is a community of scientists and software developers creating an ecosystem of Python packages for solar physics. The project includes the sunpy core package as well as a set of affiliated packages. The sunpy core package provides general purpose tools to access data from different providers, read image and time series data, and transform between commonly used coordinate systems. Affiliated packages perform more specialized tasks that do not fall within the more general scope of the sunpy core package. In this article, we give a high-level overview of the SunPy Project, how it is broader than the sunpy core package, and how the project curates and fosters the affiliated package system. We demonstrate how components of the SunPy ecosystem, including sunpy and several affiliated packages, work together to enable multi-instrument data analysis workflows. We also describe members of the SunPy Project and how the project interacts with the wider solar physics and scientific Python communities. Finally, we discuss the future direction and priorities of the SunPy Project.

Solar physics↗

Transformation of OODT CAS to Perform Larger Tasks

A computer program denoted OODT CAS has been transformed to enable performance of larger tasks that involve greatly increased data volumes and increasingly intensive processing of data on heterogeneous, geographically dispersed computers. Prior to the transformation, OODT CAS (also alternatively denoted, simply, 'CAS') [wherein 'OODT' signifies 'Object-Oriented Data Technology' and 'CAS' signifies 'Catalog and Archive Service'] was a proven software component used to manage scientific data from spaceflight missions. In the transformation, CAS was split into two separate components representing its canonical capabilities: file management and workflow management. In addition, CAS was augmented by addition of a resource-management component. This third component enables CAS to manage heterogeneous computing by use of diverse resources, including high-performance clusters of computers, commodity computing hardware, and grid computing infrastructures. CAS is now more easily maintainable, evolvable, and reusable. These components can be used separately or, taking advantage of synergies, can be used together. Other elements of the transformation included addition of a separate Web presentation layer that supports distribution of data products via Really Simple Syndication (RSS) feeds, and provision for full Resource Description Framework (RDF) exports of metadata.

Mattmann, Chris↗

Expanding Biological Repository Data Available for Sharing and Knowledge Discovery

Biology has developed next-generation data science and alternative analytical approaches with methodologies which require principal investigator (PI) experimental assay data be re-used. This new approach involves mining multiple datasets at once from various hierarchical organizations of biological complexity, while concurrently evaluating how experimental factors affect endpoints of standard assays. The purpose of the NASA Ames Life Sciences Data Archive (ALSDA) is to collect, curate, and make findable, accessible, interoperable, and reusable (FAIR) all non-human space-relevant biological data. These data include mission metadata, subject metadata, assay metadata (parameters), raw and processed assay data, assay imagery, and subject-experienced telemetry (radiation, temperature, humidity, acoustics, vibrations). ALSDA has transformed to bring current biological repository data and all future collected data into this new scientific data mining reality. It has integrated into the ‘NASA Open Science’ group of projects to facilitate a suite of new tools and workflows to improve data accessibility and reusability by implementing data management plans, automating data submission agreements, and adopting the single-point-of-entry data submission portal, originally developed by NASA GeneLab. These systems required ALSDA to develop science assay configurations for the submission portal, capturing essential assay parameters according to established norms in each sub-field within biology. The submission portal expedites data collection by enhancing ease of PI data submission, providing a user interface and specificity for which data is to be submitted. ALSDA datasets are curated to maintain rich metadata, accuracy of datasets, data transparency, provenance, and additionally ensure data are machine-readable (e.g., R and Python languages). ALSDA integration with GeneLab and its analysis portals enable higher-order physiological-level datasets be mined in conjunction with -omics datasets. As ALSDA physiological-level datasets are published (micro-computed tomography, histology, intraocular pressure, hormonal assays, immunostaining, ultrasonography), the merging of hierarchical organizations of biological complexity from spaceflight will enable new knowledge discovery approaches.

Ryan T Scott↗

Surface Biology & Geology Pathfinder Data Analysis Pipeline

NASA's future global orbital mission, currently in development as the Surface Biology and Geology (SBG) Designated Observable study, will acquire relatively high resolution solar-reflected spectroscopy and thermal infrared observations. Innovative processes must be utilized for handling the high volume of data anticipated to be collected, which is anticipated to exceed 100 terabytes/day, greater than NASA's total extant airborne hyperspectral data collection. Collecting, processing/re-processing, disseminating, and exploiting this volume of data presents new challenges. To begin addressing them, NASA is drawing upon the expertise developed from its astrophysics programs to address Earth science and applications. Specifically, NASA is adapting the science processing operations technology developed for the Kepler and TESS planet-hunting missions for imaging spectroscopy data processing. This technology development has been the foundation for the remarkable scientific successes of Kepler and TESS. The Kepler/TESS data processing technology provides a scalable architecture for robust, repeatable, and replicable science and application products while enabling the Earth science community to develop, test, and implement new algorithms. Our effort to leverage this existing capability has begun by ingesting data and applying workflows from the EO-1/Hyperion 17-year mission archive that provides globally sampled visible through shortwave infrared spectra that are representative of SBG data types and volumes. This pathfinding data processing system will help define the solutions to processing SBG data volumes and will enable the scientific community to interact with the data and processing pipeline to create new science products.

Jenkins, Jon↗

AI Curation Methods for NASA Scientific Data

The NASA Open Science Data Repository (OSDR) serves as a central hub for sharing and accessing NASA's vast collection of scientific data, supporting researchers across diverse fields. To enhance the efficiency, accuracy, and accessibility of this data, we are leveraging advanced artificial intelligence (AI) techniques as part of the AI for Curation project. By integrating large language models (LLMs) into our data curation workflow, we aim to streamline the entire process—from data submission to user interaction. This initiative focuses on improving key areas, including data ingestion, curation, and user engagement with curated datasets, impacting multiple domains and a wide user base. First, we are developing tools that can automatically parse data in various formats, using LLMs to convert unstructured data into structured, standardized formats. This reduces the manual effort required for curation, allowing curators to focus on more critical scientific analyses. Additionally, AI and machine learning (ML) models are being implemented to automate data validation and verification, ensuring the highest standards of data quality and reliability. Finally, we are creating a conversational AI agent to interact with the curated scientific studies in OSDR, helping users easily navigate the repository and access relevant data. By enhancing data discoverability and accessibility, these advancements will foster new research opportunities and promote the principles of open science.

Walter Alvarado↗

Open Science Approach to Analyze Climate-Crop Relationships in the US Leveraging GES DISC and Galaxy Workflows

Understanding the intricate relationship between climate variability and agricultural production is crucial for ensuring food security. This study investigates the impact of climate parameters, such as temperature, precipitation, and soil moisture, on major US crop yields. Adopting an open science approach, the study analyzes the impact of climate on agricultural production in the United States. The Galaxy workflow engine serves as the primary tool for integrating climate data from the Goddard Earth Sciences Data and Information Services Center (GES DISC), retrieved via the Giovanni system, with yield statistics from the United States Department of Agriculture’s National Agricultural Statistics Service (USDA NASS). Extensions for reading, preprocessing, and analyzing external data have been developed, enabling the creation of workflows within the Galaxy platform. The development of a reproducible workflow allows for the calculation of seasonal climate averages, which are then assessed for their correlation with crop yields. This methodology ensures the replicability of the research, promoting transparency and collaboration in the scientific community. Correlational and regression analyses have been applied to different sub-zones and crops. The findings from this research offer valuable insights into the relationship between climate parameters and crop yields. These insights contribute to a deeper understanding of climate-crop relationships, providing a solid foundation for informed decision-making in the agricultural sector. The high correlation values indicate a significant relationship between climate parameters and crop yields, underscoring the importance of considering climate factors in agricultural planning and policymaking. This research also exemplifies the power of open science in advancing our understanding of complex environmental and agricultural phenomena. By leveraging open data and services, it provides a robust and replicable framework for future studies in this critical field.

Open science↗

Optimizing Sample Collection and Accessibility through the Biospecimen and Tissue Sharing Collection (BTSC) Program

The Space Radiation Element (SRE) of the Human Research Program (HRP) is dedicated to establishing a robust biospecimen and tissue sharing collection (BTSC) program that enhances sample collection, tracking, access, distribution, and usability, with the goal of maximizing scientific return. By leveraging biospecimens and tissues from previous experiments, HRP effectively achieves its scientific objectives in characterizing and mitigating the human health impacts of spaceflight while optimizing resource utilization. To further improve the usability and accessibility of the current biospecimen archive, the project aims to expand upon NASA's existing resources and institutional knowledge, ensuring ongoing modernization. To facilitate seamless navigation of the program's workflow, an educational series on the BTSC program is provided to Principal Investigators (PIs). This comprehensive series equips PIs with crucial information on submitting their inventory via the BTSC Metadata Intake Form, ultimately leading to the public availability of their data on NASA's Life Science Portal (NLSP). Covering various aspects such as metadata submission instructions and backend processes for transferring metadata to the Laboratory Information Management System (LIMS), the series incorporates guidance from NASA's Biological Institutional Scientific Collection (NBISC) and Ames Life Sciences Data Archive (ALSDA). The BTSC program represents a significant stride towards enhancing the usability and accessibility of biospecimens for space research. By enabling NASA to deepen its understanding of the health implications of long-term spaceflight, this initiative plays a pivotal role in ensuring the safety and well-being of astronauts.

Shelita Renee Augustus↗

The InSAR Scientific Computing Environment 3.0: A Flexible Framework for NISAR Operational and User-Led Science Processing

The InSAR Scientific Computing Environment (ISCE) was first developed under the NASA Advanced Information Systems Technology as a flexible, extensible object-oriented framework for Interferometric Synthetic Aperture Radar (InSAR) processing. The ISCE framework uses Python 3 at the workflow level, controlling modules of compiled code for functional processing, and managing inputs, outputs, and other flow control services. The currently released version, called ISCE 2.1, is distributed to the research community through the Western North America InSAR Consortium under a research license. The ISCE team is working on the next generation of the code in order to prepare for the NASAISRO SAR (NISAR) mission operational processing. Innovations in this code include augmentation or conversion of the custom Python framework elements in ISCE with the Pyre framework, new workflows for interferometric and polarimetric stack processing, a more intuitive and graphically based user interface, and flow control for hybrid computing environments including CPU/GPU clusters, logging and error tracking facilities, and new more efficient computational modules that exploit graphical processor units (GPUs) when available. The ISCE 3.0 framework is designed to work in an operational environment as well as on a single user’s laptop or compute cluster, with services to discover capabilities and scale computations accordingly.

Buckley, Sean M.↗

NASA GeneLab RNASeq Consensus Pipeline: A Nextflow Implementation

The NASA GeneLab project (genelab.nasa.gov) seeks to accelerate space biology research through cataloging and democratizing omics data. Since raw omics data is largely inaccessible to non-bioinformaticians, GeneLab works with the scientific community to develop standard processing pipelines to generate and publish processed data. Unlike raw data, processed data has greater immediate value to a wide range of users with varying technical backgrounds and computational capabilities. Standardizing processing workflows is essential to match the pace of raw data generation, ensure reproducibility, and enable standardized processed data for comparison across datasets. Previously, GeneLab developed a standardized pipeline for processing RNAseq data, referred to as the ‘GeneLab RNAseq Consensus Pipeline (RCP)’, in collaboration with GeneLab’s Analysis Working Groups. The work presented here is a Nextflow implementation of GeneLab’s RCP that automates and accelerates data processing of RNASeq datasets hosted on GeneLab. In addition to the core data processing, the workflow also includes staging of GeneLab raw data and a robust verification and validation (V&V) program that runs after each processing step to identify errors in real-time, stop additional downstream computation, and preserve computational resources. The workflow, including the staging and V&V functionality, is open source for others to reuse and modify at https://github.com/nasa/GeneLab_Data_Processing/tree/master/RNAseq.

Jonathan Dejesus Oribello↗

NASA GeneLab RNASeq Consensus Pipeline: A Nextflow Implementation

The NASA GeneLab project (genelab.nasa.gov) seeks to accelerate space biology research through cataloging and democratizing omics data. Since raw omics data is largely inaccessible to non-bioinformaticians, GeneLab works with the scientific community to develop standard processing pipelines to generate and publish processed data. Unlike raw data, processed data has greater immediate value to a wide range of users with varying technical backgrounds and computational capabilities. Standardizing processing workflows is essential to match the pace of raw data generation, ensure reproducibility, and enable standardized processed data for comparison across datasets. Previously, GeneLab developed a standardized pipeline for processing RNAseq data, referred to as the ‘GeneLab RNAseq Consensus Pipeline (RCP)’, in collaboration with GeneLab’s Analysis Working Groups. The work presented here is a Nextflow implementation of GeneLab’s RCP that automates and accelerates data processing of RNASeq datasets hosted on GeneLab. In addition to the core data processing, the workflow also includes staging of GeneLab raw data and a robust verification and validation (V&V) program that runs after each processing step to identify errors in real-time, stop additional downstream computation, and preserve computational resources. The workflow, including the staging and V&V functionality, is open source for others to reuse and modify at https://github.com/nasa/GeneLab_Data_Processing/tree/master/RNAseq.

Jonathan D Oribello↗

Entwine Point Tiles for 3D Visualization and Querying of ICESat-2

Point Cloud data from non-optical sensors present challenges in scientific computing in both volume of data and files, even for cloud services environments. As part of the Multi-Mission Algorithm and Analysis Platform (MAAP), a joint open science platform for global biomass modelling, we’ve developed a cloud optimized workflow for using ATL08 (ICESat-2) data as a point cloud. For MAAP, the ATL08 data product is published as Entwine Point Tiles (EPT), allowing users to visualize and query the full extent of this collection interactively without pre-downloading, or preprocessing. The EPT format is a cloud-optimized point cloud data format which re-organizes points into a cloud friendly spatially indexed data structure. MAAP uses AWS S3 to store these point clouds and serves them over OGC specified APIs, 3DTiles for visualization, and WFS for querying. This workflow allows for interactive 3D visualizations in a web browser, including notebook environments and facilitates on the fly subsetting for interactive data exploration, all of which can be applied to other similar sensors.

Alex Mandel↗

Expanding Repository Data Available For Sharing and Knowledge Discovery

Some of the hardest space biology and space health challenges require data-intensive, bioinformatic, meta-analytical, and computer-assisted research approaches. These challenges include examining interdisciplinary space life science research across experiments and across interacting spaceflight hazards (radiation, altered gravity, confinement, hostile-closed environments, distance-duration from Earth). The approaches to confront these challenges involve mining multiple datasets simultaneously from various hierarchical organizations of biological complexity, all while concurrently evaluating how experimental design factors affect endpoints of standard assays. To enable this field, it is essential that principal investigators (PIs) submit data in a structure so it can be maximally re-used. The purpose of the NASA Ames Life Sciences Data Archive (ALSDA) is to collect, curate, and make publicly available all non-human space-relevant biological data. ALSDA must also ensure data are open-access, and maximally findable, accessible, interoperable, and reusable (FAIR). The scope of ALSDA data collected and submitted by PIs include subject and study design metadata, assay metadata parameters, raw and processed assay data, assay imagery/video, and subject-experienced mission data telemetry (radiation, temperature, humidity, acoustics, vibrations, etc.). ALSDA recently integrated into a collaborative group of Open Science projects to facilitate a suite of new tools and workflows that will improve data submission, accessibility, and reusability by implementing digital data submission agreements, and adopting the data management system originally developed by NASA GeneLab. ALSDA intends to bring current biological repository data and all future collected data into this new scientific data reuse reality. This new suite of tools will enable ALSDA to deploy a science curation system using scientific assay configurations for the data submission portal. It will capture essential assay parameters according to established standards in each sub-field within biology. The submission portal expedites data collection by enhancing ease of PI data submission, providing a user interface and specificity for which data is to be submitted. Data submissions can be brought into cutting-edge informatic analysis portals to enable mining of physiological, behavioral, biochemical, and imaging datasets in conjunction with ‘omics-level datasets. As ALSDA datasets are submitted, curated, and published (e.g., micro-computed tomography, histology, pulse oximetry, serum metabolites, magnetic resonance imaging, intraocular pressure, novel object recognition, etc.), the merging together of spaceflight data along this multi-hierarchical complexity of biology will enable informatics and data-intensive approaches resulting in knowledge discoveries across missions, space hazards, and biological disciplines.

Biology↗