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At least 37 records · Page 2

Novel Biomedical Device Utilizing Light-Emitting Nanostructures Developed

Sketches and chemical diagrams of state-of-the-art device and novel proposed device are presented. Current device uses a diode laser that emits into a fluorescent fluid only one wavelength and a photodetector diode that detects only one wavelength. Only one type of bacteria can be detected. The proposed device uses a quantum dot array that emits into a fluorescent fluid multiple wavelengths and an NIR 512 spectrometer that scans 0.8- to 1.7-mm wavelengths. Hundreds of different bacteria and viruses can be detected. A novel biomedical device is being developed at the NASA Glenn Research Center in cooperation with the University of Michigan. This device uses nano-structured quantum dots that emit light in the near-infrared (IR) region. The nanostructured quantum dots are used as a source and excite fluorochrome polymers coupled with antibodies that seek out and attach to specific bacteria and viruses. The fluorochrome polymers/antibodies fluoresce at specific wavelengths in the near-IR spectrum, but these wavelengths are offset from the excitation wavelength and can be detected with a tunable spectrometer. The device will be used to detect the presence of viruses and bacteria in simple fluids and eventually in more complex fluids, such as blood. Current state-of-the-art devices are limited to single bacteria or virus detection and a considerable amount of time and effort is required to prepare samples for analysis. Most importantly, the devices are quite large and cumbersome, which prohibits them from being used on the International Space Station and the space shuttles. This novel device uses nanostructured quantum dots which, through molecular beam epitaxy and highly selective annealing processes, can be developed into an illumination source that could potentially generate hundreds of specific wavelengths. As a result, this device will be able to excite hundreds of antibody/fluorochrome polymer combinations, which in turn could be used to detect hundreds of bacteria and viruses in fluids. A novel sample preparation technique that exploits micromembrane filtration and centrifugation methods has been developed for this device. The technique greatly reduces the time required to prepare the sample and the amount of sample needed to perform an accurate and comprehensive analysis. Last, and probably most important, because of the nano-light-emitting source and the novel sample preparation technique, the overall size of the device could be reduced dramatically. This device will serve as a nanoscale lab-on-a-chip for in situ microorganism detection and will enable tests to be performed on a time scale of minutes rather than days. Thus, it is ideally suited for monitoring the environmental conditions onboard the International Space Station and the space shuttles, thereby enhancing the safety of the astronauts. In addition, the device has important commercial applications, such as detecting the presence of bacteria and viruses in water at food- and beverage-processing centers, water treatment plants, and restaurants. Also, this technology has the potential to be used to detect bacteria and viruses in more complex fluids, such as blood--which in all likelihood would revolutionize blood analysis as it is performed today. This project was made possible through the Director's Discretionary Fund and is ongoing. In addition, this project provides funding to Dr. Rachel Goldman of the University of Michigan for the research and development of nanostructured quantum dots.

Scardelletti, Maximilian C.↗

Application of wave mechanics theory to fluid dynamics problems: Boundary layer on a circular cylinder including turbulence

The application of the elements of quantum (wave) mechanics to some special problems in the field of macroscopic fluid dynamics is discussed. Emphasis is placed on the flow of a viscous, incompressible fluid around a circular cylinder. The following subjects are considered: (1) the flow of a nonviscous fluid around a circular cylinder, (2) the restrictions imposed the stream function by the number of dimensions of space, and (3) the flow past three dimensional bodies in a viscous fluid, particularly past a circular cylinder in the symmetrical case.

Krzywoblocki, M. Z. V.↗

Vibrational relaxation of anharmonic oscillators in expanding flows

Although the Landau-Teller vibrational model accurately predicts vibrational excitation process in post-shock and compressing flows, it under-predicts the rate of de-excitation in cooling and expanding flows. In the present paper, detailed calculations of the vibrational relaxation process of N2 and CO in cooling flows are conducted. A coupled set of vibrational transition rate equations and quasi-one-dimensional fluid dynamic equations is solved. Multiple quantum level transition rates are computed using SSH theory. The SSH transition rate results are compared with available experimental data and other theoretical models. Vibration-vibration exchange collisions are responsible for some vibrational relaxation acceleration in situations of high vibrational temperature and low translational temperature. The present results support the relaxation mechanisms proposed by Bray and by Treanor Rich and Rehm.

Ruffin, Stephen M.↗

Unconventional inertial sensors.

Inertial sensors reviewing ring laser, electrostatic fluid sphere, magnetic resonance, superconductivity gyroscope, relativistic rotating tensor, vortex rate and quantum mechanical effect sensing

INERTIAL ACCELEROMETER↗

Improved perfect-fluid energy-momentum tensor with spin in Einstein-Cartan space-time

The description of the spin given here is classical in that it is intrinsic but not quantized. The approach in this matter is similar to, for example, the work of Bailey and Israel (1973, 1975, 1979), where the fluid particles, which have intrinsic spin, may be galaxies or clusters of galaxies. The elementary particles of these objects and the 'ferromagnetic alignment' of their quantum spins are not resorted to in order to describe a fluid with spin. Physically this means that the equation of motion for the spin tensor is a modified Fermi-Walker transport equation (Misner et al., 1973), arising as a direct result of the inclusion of spin as an intrinsic variable in the thermodynamic description of the internal energy. The variables in this description are classical variables throughout and are not microscopic fields. An improved perfect-fluid energy-momentum tensor that includes spin and torsion is presented. Use is made of a Lagrangian variational principle based on the tetrad formalism of Halbwach (1960) and the method od constraints of Ray (1972).

Ray, J. R.↗

Hard-sphere fluid in infinite dimensions

The exact Mayer series is derived for the pressure, density, and equation of state of a hard-sphere fluid in the limit of infinite space dimensions D. The Mayer series can be analytically continued into the full (cut) activity plane, and there is no sign of a phase transition. The quantum-mechanical system is also treated. For D = infinity, the fluid behaves like an ideal Bose gas and undergoes a Bose-Einstein condensation.

Wyler, D.↗

Novel Biomedical Devices Utilizing Light-Emitting Nanostructures

As part of the NASA project, we are investigating the formation, properties, and performance of QD heterostructures, to be incorporated into a novel biomedical device for detecting bacteria and/or viruses in fluids on board space vehicles. We are presently synthesizing the epitaxial quantum dot structures using molecular beam epitaxy. We recently developed a method for controlling the arrangement of QDs, based upon a combination of buffer layer growth and controlled annealing sequences. This method is promising for producing arrangements of QDs with a locally well-controlled distribution of sizes. In the future, we plan to explore selective pre-patterning of the starting surface using focused ion-beam nanopatterning, which will enable us to precisely tune the compositions, sizes, and placement of the QDs, in order laterally tune the emission and detection wavelengths of QD based devices.

Goldman, Rachel S.↗

Homogeneous quantum electrodynamic turbulence

The electromagnetic field equations and Dirac equations for oppositely charged wave functions are numerically time-integrated using a spatial Fourier method. The numerical approach used, a spectral transform technique, is based on a continuum representation of physical space. The coupled classical field equations contain a dimensionless parameter which sets the strength of the nonlinear interaction (as the parameter increases, interaction volume decreases). For a parameter value of unity, highly nonlinear behavior in the time-evolution of an individual wave function, analogous to ideal fluid turbulence, is observed. In the truncated Fourier representation which is numerically implemented here, the quantum turbulence is homogeneous but anisotropic and manifests itself in the nonlinear evolution of equilibrium modal spatial spectra for the probability density of each particle and also for the electromagnetic energy density. The results show that nonlinearly interacting fermionic wave functions quickly approach a multi-mode, dynamic equilibrium state, and that this state can be determined by numerical means.

Shebalin, John V.↗

Extrema Principles Of Dissipation In Fluids

Report discusses application of principle of least action and other variational or extrema principles to dissipation of energy and production of entropy in fluids. Principle of least action applied successfully to dynamics of particles and to quantum mechanics, but not universally accepted that variational principles applicable to thermodynamics and hydrodynamics. Report argues for applicability of some extrema principles to some simple flows.

Horne, W. Clifton↗

Boundary and Initial Condition Issues for Computational Fluid Dynamics (CFD) and Modeling and Simulation (Mod-Sim)

For many important classes of Mod-Sim problems, even quantum computing will not enable accurate predictions/computation vis-à-vis the real world due to boundary/initial condition shortfalls in terms of both range of parameters and requisite amplitudes/coverage. The Mod-Sim community needs to consider going forward the knowability of initial and boundary conditions.

Dennis M. Bushnell↗

Superfluid Helium Experiment for Spacelab 2

The Superfluid Helium Experiment is designed to study the properties of superfluid helium in zero gravity and demonstrate the operation of a versatile reusable superfluid helium experiment facility. The superfluid experiment will consist of three subexperiments. The quantized surface wave experiment is intended to contribute to an understanding of the quantum nature of He-2 and the interactions between the normal and superfluid components. The bulk fluid dynamics experiment will determine the response of the bulk helium to known accelerations. The thermal dynamics experiment will attempt to obtain a detailed understanding of the spatial distribution of temperatures and the thermal frequency spectrum in the bulk liquid. In addition, the superfluid helium cryostat will be instrumented to measure its performance in several critical areas.

Mason, P.↗

Frequency-dependent hydrodynamic inductance and the determination of the thermal and quantum noise of a superfluid gyroscope

We reexamine mass flow in a superfluid gyroscope containing a superfluid Josephson weak link. We introduce a frequency-dependent hydrodynamic inductance to account for an oscillatory flow of the normal fluid component in the sensing loop. With this hydrodynamic inductance, we derive the thermal phase noise, and hence the thermal rotational noise of the gyroscope. We examine the thermodynamic stability of the system based on an analysis of the free energy. We derive a quantum phase noise, which is analogous to the zero-point motion of a simple harmonic oscillator. The configuration of the studied gyroscope is analogous to a conventional superconducting RF SQUID. We show that the gyroscope has very low intrinsic noise (1.9x10(-13) rad s(-1)/root Hz), and it can potentially be applied to study general relativity, Earth science, and to improve global positioning systems (GPS).

Penanen, Konstantin↗

Lagrange thermodynamic potential and intrinsic variables for He-3 He-4 dilute solutions

For a two-fluid model of dilute solutions of He-3 in liquid He-4, a thermodynamic potential is constructed that provides a Lagrangian for deriving equations of motion by a variational procedure. This Lagrangian is defined for uniform velocity fields as a (negative) Legendre transform of total internal energy, and its primary independent variables, together with their thermodynamic conjugates, are identified. Here, similarities between relations in classical physics and quantum statistical mechanics serve as a guide for developing an alternate expression for this function that reveals its character as the difference between apparent kinetic energy and intrinsic internal energy. When the He-3 concentration in the mixtures tends to zero, this expression reduces to Zilsel's formula for the Lagrangian for pure liquid He-4. An investigation of properties of the intrinsic internal energy leads to the introduction of intrinsic chemical potentials along with other intrinsic variables for the mixtures. Explicit formulas for these variables are derived for a noninteracting elementary excitation model of the fluid. Using these formulas and others also derived from quantum statistical mechanics, another equivalent expression for the Lagrangian is generated.

Jackson, H. W.↗

Some Thermodynamic Considerations on the Physical and Quantum Nature of Space and Time

It is suggested that the Planck h = m(sub k)c Lambda(sub k) and the Boltzmann k = m(sub k)c nu(sub k)Constants have stochastic foundation. It is further suggested that a body of fluid at equilibrium is composed of a spectrum of molecular clusters (energy levels) the size of which are governed by the Maxwell-Boltzmann distribution function. Brownian motions are attributed to equilibrium between suspensions and molecular clusters. Atomic (molecular) transition between different size atomic- (molecular-) clusters (energy levels) is shown to result in emission/absorption of energy in accordance with Bohr's theory of atomic spectra. Physical space is identified as a tachyonic fluid that is Dirac's stochastic ether or de Broglie's hidden thermostat. Compressibility of physical space, in accordance with Planck's compressible ether, is shown to result in the Lorentz-Fitzgerald contraction, thus providing a causal explanation of relativistic effect in accordance with the perceptions of Poincare and Lorentz. The invariant Schrodinger equation is derived from the invariant Bernoulli equation for incompressible potential flow. Following Heisenberg a temporal uncertainty relation is introduced as Delta(nu(sub Beta)) Delta(Rho(sub Beta)) > = k.

Sohrab, Siavash H.↗

Temperature dependence of penetration depth in thin film niobium

A novel technique is presented which should allow precise determination of the temperature dependence of the inductance, and hence of the penetration depth, of superconducting niobium thin-film structures. Four niobium thin-film stripline inductors are arranged in a bridge configuration, and inductance differences are measured using a potentiometric technique with a SQUID (superconducting quantum interference device) as the null detector. Numerical simulations of the stripline inductances are presented which allow the performance of the measurement technique to be evaluated. The prediction of the two-fluid model for the penetration-depth temperature dependence is given for reduced temperatures of 0.3 to 0.9. The experimental apparatus and its resolution and accuracy are discussed.

More, N.↗

A new rotational relaxation model for use in hypersonic computational fluid dynamics

The theoretical basis for the Landau-Teller equation commonly used to model rotational nonequilibrium is reviewed. Several assumptions underlying this model are indicated to be unrealistic for rarefied hypersonic flow. A new rotational nonequilibrium model based on recent measurements up to 2000K of quantum state transition rates is presented. The new model is applied to the continuum study of normal shock wave structure using both the Burnett equations and a simplified nonlinear constitutive relation. Comparisons are made between shock wave temperature profiles generated from the new model and those generated using the Landau-Teller model. Comparisons of shock reciprocal thicknesses between experimental data for nitrogen and continuum solutions using both rotational models are made. The new rotational model agrees well with experiment up to Mach 6, and under predicts shock thickness at higher Mach numbers. The Landau-Teller model agrees well with experimental shock thickness up to Mach 3, and over predicts the thickness at higher Mach numbers. A modification to the rotational collision number in the Landau-Teller model is found to give results which agree with experimental shock thicknesses at all Mach numbers up to 11.

Chapman, Dean E.↗

Subsonic and Supersonic Effects in Bose-Einstein Condensate

A paper presents a theoretical investigation of subsonic and supersonic effects in a Bose-Einstein condensate (BEC). The BEC is represented by a time-dependent, nonlinear Schroedinger equation that includes terms for an external confining potential term and a weak interatomic repulsive potential proportional to the number density of atoms. From this model are derived Madelung equations, which relate the quantum phase with the number density, and which are used to represent excitations propagating through the BEC. These equations are shown to be analogous to the classical equations of flow of an inviscid, compressible fluid characterized by a speed of sound (g/Po)1/2, where g is the coefficient of the repulsive potential and Po is the unperturbed mass density of the BEC. The equations are used to study the effects of a region of perturbation moving through the BEC. The excitations created by a perturbation moving at subsonic speed are found to be described by a Laplace equation and to propagate at infinite speed. For a supersonically moving perturbation, the excitations are found to be described by a wave equation and to propagate at finite speed inside a Mach cone.

Zak, Michail↗