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Customizable adaptive regularization techniques for B-spline modeling

B-spline models are a powerful way to represent scientific data sets with a functional approximation. However, these models can suffer from spurious oscillations when the data to be approximated are not uniformly distributed. Model regularization (i.e., smoothing) has traditionally been used to minimize these oscillations; unfortunately, it is sometimes impossible to sufficiently remove unwanted artifacts without smoothing away key features of the data set. In this article, we present a method of model regularization that preserves significant features of a data set while minimizing artificial oscillations. Our method varies the strength of a smoothing parameter throughout the domain automatically, removing artifacts in poorly-constrained regions while leaving other regions unchanged. Further, the proposed method selectively incorporates regularization terms based on first and second derivatives to maintain model accuracy while minimizing numerical artifacts. The behavior of our method is validated on a collection of two- and three-dimensional data sets produced by scientific simulations. In addition, a key tuning parameter is highlighted and the effects of this parameter are presented in detail. This paper is an extension of our previous conference paper at the 2022 International Conference on Computational Science (ICCS) (Lenz et al., 2022).

97 MATHEMATICS AND COMPUTING↗

Monte Carlo event generator for initial conditions of conserved charges in nuclear geometry

At top collider energies where baryon stopping is negligible, the initial state of heavy-ion collisions is overall charge neutral and predominantly composed of gluons. Nevertheless, there can also be significant local fluctuations of the baryon number, strangeness, and electric charge densities about zero, perturbatively corresponding to the production of quark/antiquark pairs. These previously ignored local charge fluctuations can permit the study of charge diffusion in the quark-gluon plasma (QGP), even at top collider energies. In this paper we present a new model denoted ICCING (initial conserved charges in nuclear geometry) which can reconstruct the initial conditions of conserved charges in the QGP by sampling a (g→q¯q) splitting probability over the initial energy density. We find that the new charge distributions generally differ from the bulk energy density; in particular, the strangeness distribution is significantly more eccentric than standard bulk observables and appears to be associated with the geometry of hot spots in the initial state. The new information provided by these conserved charges opens the door to studying a wealth of new charge- and flavor-dependent correlations in the initial state and ultimately the charge transport parameters of the QGP.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Computed Tomography Scanning and Geophysical Measurements of the CarbonSAFE Seal Integrity Wells in the Illinois Basin

The U.S. Department of Energy’s (DOE) National Energy Technology Laboratory (NETL) researchers in Morgantown, West Virginia, utilized computed tomography (CT) facilities and the Multi-Sensor Core Logger (MSCL) to evaluate the integrity of three cores (Geophysical Monitor #2 (GM2), Verification Well #1 (VW #1), and Wabash #1 for the Illinois Basin Carbon Storage Assurance Facility Enterprise (CarbonSAFE) efforts. This work was carried out in collaboration with the Illinois State Geological Survey (ISGS) as part of their efforts to analyze cores from two field locations, including the Illinois Basin-Decatur Project (IBDP) and second stage Illinois Industrial Carbon Capture and Storage (IL-ICCS) sites at Decatur, Illinois, and the Wabash CarbonSAFE project at the Wabash Valley Resources Integrated Gasification Combined Cycle plant in Terre Haut, Indiana. The results of this study are presented in several formats and are available online on the Energy Data eXchange (EDX). The rock characterization was conducted using non-destructive techniques, allowing for future analysis of the cores. While the equipment used did not provide direct visualization of shale pore space, it allowed for detection of fractures and discontinuities. Low resolution CT imagery with the NETL medical CT scanner was performed on the entire core. Qualitative analysis of the medical CT images, coupled with x-ray fluorescence (XRF), P-wave, and magnetic susceptibility measurements from the MSCL were utilized to identify areas of interest for further study as well as fractured zones. The ability to quickly identify key areas for more detailed study with higher resolution will save time and resources in future studies. The combination of methods used provided a multi-scale analysis of this core and provided both a macro and micro description of the core that is relevant for many subsurface energy-related examinations traditionally performed at NETL.

58 GEOSCIENCES↗

Energy Storage and Decarbonization Analysis for Energy Regulators: Technical Analysis for the Illinois Commerce Commission

Jurisdictions around the world are enacting and enforcing an increasing number of policies to fight climate change, leading to higher penetration of variable renewable energy (VRE) and energy storage systems (ESSs) in the power grid. One of the biggest challenges associated with this process is the evaluation of the appropriate amount of ESS required to mitigate the variability of the VREs and achieve decarbonization goals of a particular jurisdiction. This report presents methodologies developed and results obtained for determining the minimum amount of ESS required to adequately serve load in a system where fossil fueled generators are being replaced by VREs over the next two decades. This technical analysis is performed by Sandia National Laboratories for the DOE Office of Electricity Energy Storage Program in collaboration with the Illinois Commerce Commission (ICC). The Illinois MISO Zone 4 is used as a case study. Several boundary conditions are investigated in this analysis including capacity adequacy and energy adequacy to determine the quantity of ESS required for MISO Zone 4. Multiple scenarios are designed and evaluated to incorporate the impact of varying capacity values of VREs and on the resource adequacy of the system. Several retirement scenarios involving fossil-fueled assets are also considered. Based on the current plans of new additions and retirements of generating assets, the results of the technical analysis indicate that Illinois MISO Zone 4 will require a significant quantity of ESS to satisfy their electricity demand over the next two decades.

25 ENERGY STORAGE↗

Support for U.S. Participants at the 18 th International Congress on Catalysis

The 18 th International Congress on Catalysis (ICC) was held Lyon, France on July 14-19, 2024. It provided a premier technical gathering in surface and organometallic catalysis, industrial homogeneous and heterogeneous catalysis, electrocatalysis, photocatalysis, and catalysis in condensed media. This meeting brough together participants from academia, industry, and national laboratories. The organization that overseed this meeting was the Council of the International Congress on Catalysis. This international committee has over 27 signature countries. The United States is represented in the Council of the International Congress on Catalysis through two permanent representatives. These representatives are elected by the Board of Directors of the North American Catalysis Society (NACS), an organization which coordinates and overseas the activities of 12 largely autonomous clubs within the United States, Canada, and Mexico. The critical importance of catalysis is reflected by the fact that 25-30% of all manufactured goods in the United States involve at least one catalytic step. Because advances in a large number of catalytic processes, which are crucial to U.S. interests, were presented at this meeting, it was important to ensure participation from both the U.S. academic and the industrial sectors.

02 PETROLEUM↗

SolarAPP+ Enhancements and Commercialization (Final Technical Report)

With millions of distributed photovoltaic (PV) systems expected to be installed over the next five years, the permitting and inspection processes of authorities having jurisdiction (AHJs) may become overburdened, causing delays and increased costs for installed systems (Cruce et al. 2022). The central goal of this project was to automate and streamline permitting processes for distributed PV systems and complementary technologies, such as battery storage. Deploying automated permitting has been hypothesized to reduce permit review times, resulting in reduced costs and improved customer experience. This has the potential to expand the PV and PV-plus-storage market nationwide. The National Renewable Energy Laboratory (NREL) and its project partners, including UL Solutions, the Interstate Renewable Energy Council (IREC), the International Code Council (ICC), and more, developed the Solar Automated Permit Processing (SolarAPP+™) software platform to reduce permit review times. NREL and its partners also collaborated with the solar industry, the building safety community, and local governments to develop SolarAPP+.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

National Cost-Effectiveness of the Residential Provisions of the 2024 IECC

This analysis focuses on single-family and low-rise multifamily residential buildings based on the International Energy Conservation Code (IECC). The IECC is developed by the International Code Council (ICC) on a 3-year cycle through a public development and consensus process. While proponents of code changes often include the energy and cost-effectiveness criteria for their respective code change, the IECC process does not include an energy or cost-effectiveness analysis of the entire edition of the code. PNNL evaluated the cost effectiveness of the changes in the prescriptive and mandatory residential provisions of the 2024 edition of the IECC, hereafter referred as the 2024 IECC, compared to those in the prior edition, the 2021 IECC. The simulated performance path and the Energy Rating Index (ERI) path (introduced in the 2015 IECC) are not considered in this analysis due to the wide variation in building construction characteristics that are allowed.

2024 IECC↗

Generalizing mkFit and its Application to HL-LHC

mkFit is an implementation of the Kalman filter-based track reconstruction algorithm that exploits both thread- and data-level parallelism. In the past few years the project transitioned from the R&D phase to deployment in the Run-3 offline workflow of the CMS experiment. The CMS tracking performs a series of iterations, targeting reconstruction of tracks of increasing difficulty after removing hits associated to tracks found in previous iterations. mkFit has been adopted for several of the tracking iterations, which contribute to the majority of reconstructed tracks. When tested in the standard conditions for production jobs, speedups in track pattern recognition are on average of the order of 3.5x for the iterations where it is used (3-7x depending on the iteration). Multiple factors contribute to the observed speedups, including vectorization and a lightweight geometry description, as well as improved memory management and single precision. Efficient vectorization is achieved with both the icc and the gcc (default in CMSSW) compilers and relies on a dedicated library for small matrix operations, Matriplex, which has recently been released in a public repository. While the mkFit geometry description already featured levels of abstraction from the actual Phase-1 CMS tracker, several components of the implementations were still tied to that specific geometry. We have further generalized the geometry description and the configuration of the run-time parameters, in order to enable support for the Phase-2 upgraded tracker geometry for the HL-LHC and potentially other detector configurations. The implementation strategy and high-level code changes required for the HL-LHC geometry are presented. Speedups in track building from mkFit imply that track fitting becomes a comparably time consuming step of the tracking chain.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

PAC in DESI. II. Galaxy-halo connection into the $10^{6}{\rm M}_{\odot}$ frontier

Understanding dwarf galaxy formation is crucial for testing dark matter models and reionization physics. However, constructing stellar-mass complete spectroscopic samples at low masses is increasingly difficult, and the potential existence of a local void complicates studies in an average environment. The Photometric object Around Cosmic webs (PAC) method, which combines deep photometric and spectroscopic data to measure the excess surface density $\bar{n}_2w_{\rm{p}}(r_{\rm{p}})$ of photometric objects around spectroscopic tracers, offers a promising path forward. We model 349 $\bar{n}_2w_{\rm{p}}(r_{\rm{p}})$ measurements from DESI Y1 BGS and DECaLS, reaching $M_*=10^{6.4}\,{\rm M}_{\odot}$, using a stellar mass-halo mass relation (SHMR)-based subhalo abundance matching framework applied to two high-resolution $N$-body simulations from the Jiutian suite. The resulting SHMR is constrained down to $M_{\rm h}\simeq10^{8.0}\,h^{-1}{\rm M}_{\odot}$, revealing a clear upturn at $\sim10^{10.0}\,h^{-1}{\rm M}_{\odot}$ toward lower masses, indicating rising star-formation efficiency (SFE) in small haloes. This feature persists under extensions of the model that allow mass-dependent scatter, reionization-induced suppression of the halo occupation fraction, galaxy assembly bias, and alternative cosmologies. Combining with the results from Paper I, we find that central red galaxies dominate the low-mass regime. Our results motivate a hypothesis in which SFE is significantly higher than previously thought prior to reionization, enabling relatively massive galaxies to form in small haloes. These systems are subsequently quenched by the UV background, producing the central red dwarf galaxies observed. Finally, we obtain $3σ$ and $5σ$ upper mass bounds of $10^{8.80}\,h^{-1}{\rm M}_{\odot}$ and $10^{10.24}\,h^{-1}{\rm M}_{\odot}$ on the smallest haloes required to exist.

Xu, Kun [Pennsylvania U.; Durham U., ICC; Tsung-Da↗

Data Release 1 of the Dark Energy Spectroscopic Instrument

In 2021 May the Dark Energy Spectroscopic Instrument (DESI) collaboration began a 5 yr spectroscopic redshift survey to produce a detailed map of the evolving three-dimensional structure of the Universe between z = 0 and z ≈ 4. DESI’s principal scientific objectives are to place precise constraints on the equation of state of dark energy, the gravitationally driven growth of large-scale structure, and the sum of the neutrino masses, and to explore the observational signatures of primordial inflation. We present DESI DR1, which consists of all data acquired during the first 13 months of the DESI main survey, as well as a uniform reprocessing of the DESI Survey Validation data, which were previously made public in the DESI Early Data Release. The DR1 main survey includes high-confidence redshifts for 18.7M objects, of which 13.1M are spectroscopically classified as galaxies, 1.6M as quasars, and 4M as stars, making DR1 the largest sample of extragalactic redshifts ever assembled. We summarize the DR1 observations, the spectroscopic data-reduction pipeline and data products, large-scale structure catalogs, value-added catalogs, and describe how to access and interact with the data. In addition to fulfilling its core cosmological objectives with unprecedented precision, we expect DR1 to enable a wide range of transformational astrophysical studies and discoveries.

79 ASTRONOMY AND ASTROPHYSICS↗

Cosmological constraints from the DESI DR1 joint power spectrum and bispectrum analysis

We derive cosmological parameter constraints from the Dark Energy Spectroscopic Instrument (DESI) Data Release 1 (DR1) galaxy clustering data, based on a joint full-shape analysis of the power spectrum multipoles and the bispectrum monopole using the ShapeFit framework. This is the follow-up of our previous work, in which we obtained for the first time constraints on the ShapeFit parameters using the bispectrum of DESI DR1. Here we present the first ShapeFit cosmological inference results using the bispectrum of DESI DR1. We recover values for the matter density parameter and Hubble constant of respectively $Ω_m=0.310\pm0.012$ and $H_0=[68.92\pm0.97]\,\mathrm{km\, s^{-1} Mpc^{-1}}$, consistent with previous results from the full DESI DR1 dataset that did not use the bispectrum signal. The inclusion of the bispectrum significantly tightens the constraints on the amplitude of fluctuations, reducing the error-bars in $\ln(A_s\times10^{10})$ by approximately 20%, compared to using the power spectrum alone. We also explore extended cosmological models by performing fits for the evolving dark energy equation of state $w_0w_a$, and the sum of neutrino masses $\sum m_ν$. In these cases, we obtain constraints slightly larger than the ones from previous works from the DESI collaboration, due to not combining the full-shape results with other probes in all tracers. We find no strong evidence of deviations from standard $Λ$CDM, with the dark energy equation-of-state remaining within 2$σ$ from a cosmological constant $Λ$, and the neutrino mass being consistent with the normal hierarchy, $\sum m_ν<0.1\,[eV]$ at 95% confidence limit. These constraints are broadly consistent with other DESI DR1 analyses, thus validating the robustness of the ShapeFit compression approach and the inclusion of the bispectrum for cosmological inference.

Novell-Masot, S. [ICC, Barcelona U.; Geneva U., De↗

Cosmological constraints from the DESI DR1 joint power spectrum and bispectrum analysis

We derive cosmological parameter constraints from the Dark Energy Spectroscopic Instrument (DESI) Data Release 1 (DR1) galaxy clustering data, based on a joint full-shape analysis of the power spectrum multipoles and the bispectrum monopole using the ShapeFit framework. This is the follow-up of our previous work, in which we obtained for the first time constraints on the ShapeFit parameters using the bispectrum of DESI DR1. Here we present the first ShapeFit cosmological inference results using the bispectrum of DESI DR1. We recover values for the matter density parameter and Hubble constant of respectively $Ω_m=0.310\pm0.012$ and $H_0=[68.92\pm0.97]\,\mathrm{km\, s^{-1} Mpc^{-1}}$, consistent with previous results from the full DESI DR1 dataset that did not use the bispectrum signal. The inclusion of the bispectrum significantly tightens the constraints on the amplitude of fluctuations, reducing the error-bars in $\ln(A_s\times10^{10})$ by approximately 20%, compared to using the power spectrum alone. We also explore extended cosmological models by performing fits for the evolving dark energy equation of state $w_0w_a$, and the sum of neutrino masses $\sum m_ν$. In these cases, we obtain constraints slightly larger than the ones from previous works from the DESI collaboration, due to not combining the full-shape results with other probes in all tracers. We find no strong evidence of deviations from standard $Λ$CDM, with the dark energy equation-of-state remaining within 2$σ$ from a cosmological constant $Λ$, and the neutrino mass being consistent with the normal hierarchy, $\sum m_ν<0.1\,[eV]$ at 95% confidence limit. These constraints are broadly consistent with other DESI DR1 analyses, thus validating the robustness of the ShapeFit compression approach and the inclusion of the bispectrum for cosmological inference.

Novell-Masot, S. [ICC, Barcelona U.; Geneva U., De↗

DESI DR2 Results IV: Alcock-Paczyński Measurements from the Lyman Alpha Forest and Cosmological Constraints

We present Alcock-Paczyński (AP) measurements from the full shape of Lyman-$α$ (Ly$α$) forest correlation functions measured from the second data release (DR2) of the Dark Energy Spectroscopic Instrument (DESI). Our measurements include information from the Ly$α$ forest auto-correlation and its cross-correlation with quasars. We constrain the AP effect with $1\%$ precision at an effective redshift $z_\mathrm{eff}=2.33$, which is twice as tight as the Baryon Acoustic Oscillation (BAO) constraint from the same data. When using the joint Ly$α$ AP and BAO results, we measure the ratios $D_\text{H}(z_\mathrm{eff})/r_\text{d}=8.600 \pm 0.066$ and $D_\text{M}(z_\mathrm{eff})/r_\text{d}=39.32 \pm 0.33$, where $D_\text{M}$ is the transverse comoving distance, $D_\text{H}$ is the Hubble distance, and $r_\text{d}$ is the sound horizon at the drag epoch. Assuming $Λ$CDM, Ly$α$ forest measurements combined with a nucleosynthesis prior produce a constraint on the Hubble constant $H_0=66.5\pm1.3\,\mathrm{km\,s^{-1}\,Mpc^{-1}}$. The Ly$α$ AP result corresponds to a matter fraction constraint $Ω_\text{m}=0.325\pm0.018$ in $Λ$CDM, which is $1.4σ$ higher than DESI BAO. This impacts the DESI results relative to the Cosmic Microwave Background (CMB), slightly reducing their discrepancy from $2.4σ$ to $2.2σ$. We present updated constraints on extended models using the joint DESI DR2 BAO and Ly$α$ forest full shape data, together with external data sets. When considering a time-evolving dark energy equation of state parametrized by $w_0$ and $w_a$, we find it is preferred over $Λ$CDM at $2.7σ$ for the combination of DESI and CMB data, and at $3.2σ$ when also including supernovae. With the new Ly$α$ AP measurement, DESI provides its most precise anchor for the expansion history at $z > 1$ in the matter-dominated Universe.

Adame, A. G. [Vienna U.] (ORCID:0009000505949391)↗

DESI DR2 Results I: Baryon Acoustic Oscillations from the Lyman Alpha Forest

We present the Baryon Acoustic Oscillation (BAO) measurements with the Lyman-alpha (LyA) forest from the second data release (DR2) of the Dark Energy Spectroscopic Instrument (DESI) survey. Our BAO measurements include both the auto-correlation of the LyA forest absorption observed in the spectra of high-redshift quasars and the cross-correlation of the absorption with the quasar positions. The total sample size is approximately a factor of two larger than the DR1 dataset, with forest measurements in over 820,000 quasar spectra and the positions of over 1.2 million quasars. We describe several significant improvements to our analysis in this paper, and two supporting papers describe improvements to the synthetic datasets that we use for validation and how we identify damped LyA absorbers. Our main result is that we have measured the BAO scale with a statistical precision of 1.1% along and 1.3% transverse to the line of sight, for a combined precision of 0.65% on the isotropic BAO scale at $z_{eff} = 2.33$. This excellent precision, combined with recent theoretical studies of the BAO shift due to nonlinear growth, motivated us to include a systematic error term in LyA BAO analysis for the first time. We measure the ratios $D_H(z_{eff})/r_d = 8.632 \pm 0.098 \pm 0.026$ and $D_M(z_{eff})/r_d = 38.99 \pm 0.52 \pm 0.12$, where $D_H = c/H(z)$ is the Hubble distance, $D_M$ is the transverse comoving distance, $r_d$ is the sound horizon at the drag epoch, and we quote both the statistical and the theoretical systematic uncertainty. The companion paper presents the BAO measurements at lower redshifts from the same dataset and the cosmological interpretation.

79 ASTRONOMY AND ASTROPHYSICS↗

Optimization of Species-Selective Reversible Proteasome Inhibitors for the Treatment of Malaria

Abstract Malaria remains a critical global health challenge, with increasing resistance to frontline therapies necessitating novel drug targets. The proteasome has emerged as a promising target for antimalarial drug discovery. This study describes efforts to optimize a series of species-selective reversible inhibitors targeting the Plasmodium falciparum 20S proteasome. Starting from the carboxypiperidine scaffold identified through a high-throughput viability screen, we conducted iterative structure–activity relationship studies, leading to the development of highly potent and selective inhibitors with good oral bioavailability. Lead compounds demonstrated nanomolar potency against P. falciparum blood-stage parasites and selective inhibition of the parasite proteasome over the human counterpart. Cryo-EM structural studies confirmed binding at the β5 subunit, while in vivo pharmacokinetic studies identified promising candidates for further development. These findings support proteasome inhibition as a viable strategy for novel antimalarial drug development.

Gahalawat, Suraksha [UT Southwestern Medical Cente↗

Changing-look Active Galactic Nuclei from the Dark Energy Spectroscopic Instrument. II. Statistical Properties from the First Data Release

We present the identification of changing-look active galactic nuclei (CL-AGNs) from the Dark Energy Spectroscopic Instrument First Data Release and Sloan Digital Sky Survey Data Release 16 at z≤ 0.9. To confirm the CL-AGNs, we utilize spectral flux calibration assessment via an [O iii]-based calibration, pseudophotometry examination, and visual inspection. This rigorous selection process allows us to compile a statistical catalog of 561 CL-AGNs, encompassing 527 Hβ, 149 Hα, and 129 Mg ii CL behaviors. In this sample, we find (1) a 283:278 ratio of turn-on to turn-off CL-AGNs. (2) The median Eddington ratio for CL-AGNs in the dim state is approximately λ$_{Edd}$ ∼ 0.01. (3) A strong correlation between the change in the luminosity of the broad emission lines (BELs) and variation in the continuum luminosity, with Mg ii and Hβ displaying similar responses during CL phases. (4) The Baldwin–Phillips–Terlevich diagram for CL-AGNs shows no statistical difference from the general AGN catalog. (5) Five CL-AGNs are associated with asymmetrical mid-infrared flares, possibly linked to tidal disruption events. Given the large CL-AGN sample and the stochastic sampling of spectra, we propose that some CL phenomena are inherently due to typical AGN variability during low accretion rates, particularly for CL phenomenon only occurring on one BEL. Finally, we introduce a monotonically dimming CL phase for objects characterized by a gradual decline over decades in the light curve and the complete disappearance of entire BELs in faint spectra, indicative of a real transition in the accretion disk.

79 ASTRONOMY AND ASTROPHYSICS↗

Characterization of DESI fiber assignment incompleteness effect on 2-point clustering and mitigation methods for DR1 analysis

We present an in-depth analysis of the fiber assignment incompleteness in the Dark EnergySpectroscopic Instrument (DESI) Data Release 1 (DR1). This incompleteness is caused by therestricted mobility of the robotic fiber positioner in the DESI focal plane, which limits thenumber of galaxies that can be observed at the same time, especially at small angular separations.As a result, the observed clustering amplitude is suppressed in a scale-dependent manner, which,if not addressed, can severely impact the inference of cosmological parameters. We discuss themethods adopted for simulating fiber assignment on mocks and data. In particular, we introducethe fast fiber assignment (FFA) emulator, which was employed to obtain the power spectrumcovariance adopted for the DR1 full-shape analysis. We present the mitigation techniques,organised in two classes: measurement stage and model stage. We then use high fidelity mocks as areference to quantify both the accuracy of the FFA emulator and the effectiveness of the differentmeasurement-stage mitigation techniques. This complements the studies conducted in a parallelpaper for the model-stage techniques, namely the θ-cut approach. We find that pairwiseinverse probability (PIP) weights with angular upweighting recover the “true” clustering in allthe cases considered, in both Fourier and configuration space. Notably, we present the first everpower spectrum measurement with PIP weights from real data.

79 ASTRONOMY AND ASTROPHYSICS↗

Validation of the DESI DR2 Ly$\alpha$ BAO analysis using synthetic datasets

The second data release (DR2) of the Dark Energy Spectroscopic Instrument (DESI), containing data from the first three years of observations, doubles the number of Lyman-$\alpha$ (Ly$\alpha$) forest spectra in DR1 and it provides the largest dataset of its kind. To ensure a robust validation of the Baryonic Acoustic Oscillation (BAO) analysis using Ly$\alpha$ forests, we have made significant updates compared to DR1 to both the mocks and the analysis framework used in the validation. In particular, we present CoLoRe-QL, a new set of Ly$\alpha$ mocks that use a quasi-linear input power spectrum to incorporate the non-linear broadening of the BAO peak. We have also increased the number of realisations used in the validation to 400, compared to the 150 realisations used in DR1. Finally, we present a detailed study of the impact of quasar redshift errors on the BAO measurement, and we compare different strategies to mask Damped Lyman-$\alpha$ Absorbers (DLAs) in our spectra. The BAO measurement from the Ly$\alpha$ dataset of DESI DR2 is presented in a companion publication.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗