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31 records · Page 2

Activation of G proteins mediates flow-induced prostaglandin E2 production in osteoblasts

Interstitial fluid flow may play a role in load-induced bone remodeling. Previously, we have shown that fluid flow stimulates osteoblast production of cAMP inositol trisphosphate (IP3), and PGE2. Flow-induced increases in cAMP and IP3 were shown to be a result of PG production. Thus, PGE2 production appears to be an important component in fluid flow induced signal transduction. In the present study, we investigated the mechanism of flow-induced PGE2 synthesis. Flow-induced a 20-fold increase in PGE2 production in osteoblasts. Increases were also observed with ALF4-(10mM) (98-fold), an activator of guanidine nucleotide-binding proteins (G proteins), and calcium ionophore A23187 (2 microM) (100-fold) in stationary cells. We then investigated whether flow stimulation is mediated by G proteins and increases in intracellular calcium. Flow-induced PGE2 production was inhibited by the G protein inhibitors GDP beta S (100 microM) and pertussis toxin (1 microgram/ml) by 83% and 72%, respectively. Chelation of extracellular calcium by EGTA (2 mM) and intracellular calcium by quin-2/AM (30 microM) blocked flow stimulation by 87% and 67%, respectively. These results suggest that G proteins and calcium play an important role in mediating mechanochemical signal transduction in osteoblasts.

NASA Discipline Cell Biology↗

Developing Passenger Demand Models for International Aviation from/to Egypt: A Case Study of Cairo Airport and Egyptair

This research is concerned with developing passenger demand models for international aviation from/to Egypt. In this context, aviation sector in Egypt is represented by the biggest and main airport namely Cairo airport as well as by the main Egyptian international air carrier namely Egyptair. The developed models utilize two variables to represent aviation demand, namely total number of international flights originating from and attracted to Cairo airport as well as total number of passengers using Egyptair international flights originating from and attracted to Cairo airport. Such demand variables were related, using different functional forms, to several explanatory variables including population, GDP and number of foreign tourists. Finally, two models were selected based on their logical acceptability, best fit and statistical significance. To demonstrate usefulness of developed models, these were used to forecast future demand patterns.

Abbas, Khaled A.↗

Glow Discharge Plasma Demonstrated for Separation Control in the Low-Pressure Turbine

Flow separation in the low-pressure turbine (LPT) is a major barrier that limits further improvements of aerodynamic designs of turbine airfoils. The separation is responsible for performance degradation, and it prevents the design of highly loaded airfoils. The separation can be delayed, reduced, or eliminated completely if flow control techniques are used. Successful flow control technology will enable breakthrough improvements in gas turbine performance and design. The focus of this research project was the development and experimental demonstration of active separation control using glow discharge plasma (GDP) actuators in flow conditions simulating the LPT. The separation delay was shown to be successful, laying the foundation for further development of the technologies to practical application in the LPT. In a fluid mechanics context, the term "flow control" means a technology by which a very small input results in a very large effect on the flow. In this project, the interest is to eliminate or delay flow separation on LPT airfoils by using an active flow control approach, in which disturbances are dynamically inserted into the flow, they interact with the flow, and they delay separation. The disturbances can be inserted using a localized, externally powered, actuating device, examples are acoustic, pneumatic, or mechanical devices that generate vibrations, flow oscillations, or pulses. A variety of flow control devices have been demonstrated in recent years in the context of the external aerodynamics of aircraft wings and airframes, where the incoming flow is quiescent or of a very low turbulence level. However, the flow conditions in the LPT are significantly different because there are high levels of disturbances in the incoming flow that are characterized by high free-stream turbulence intensity. In addition, the Reynolds number, which characterizes the viscous forces in the flow and is related to the flow speed, is very low in the LPT passages.

Ashpis, David e.↗

Application of Satellite Observations to Manage Natural Disasters in the Lake Victoria Basin

Lake Victoria, the second largest fresh water lake in the Eastern part of Africa is a vital natural resource for the economic well being and prosperity of over 30 million people located in riparian regions of Uganda, Kenya and Tanzania. It covers a large area of about 68,870 km2 and produces a GDP of about US $30 billion per year. The region is also very much prone to natural disasters such as severe floods during heavy precipitation periods in the Eastern part of Africa. In addition to floods, the precipitation also produces large infestations of mosquito larvae due to the standing water in many areas. This further causes multiple vector borne diseases such as Malaria, Rift Valley Fever and more. These problems are of serious concern and require active and aggressive surveillance and management to minimize the loss of human and animal lives and property damage. Satellite imagery and observations along with the in situ measurements provide a great tool to analyze and study this area and inform the policy makers to make calculated policy decisions which are more beneficial to the environment. Recently, NASA and USAID have joined forces with the Regional Center for Mapping of Resources for Development (RCMRD) located in Nairobi, Kenya to utilize multiple NASA sensors such as TRMM, SRTM and MODIS to develop flood potential maps for the Lake Victoria Basin. The idea is to generate a flood forecasts and "nowcasts" that can be sent to the disaster management organizations of Uganda, Kenya, and Tanzania. Post flood event satellite imagery is becoming a common tool to assess the areas inundated by flooding. However, this work is unique undertaking by utilizing land imaging and atmospheric satellites to build credible flood potential maps. At same time, we are also studying the potential occurrence and spread of Rift Valley Fever disease based on the short term climate records and precipitation data. These activities require multi-nation coordination and agreements and multiple operational agencies within each respective country. It also requires credible in situ data such as precipitation, river flow rates and lake levels to further validate the global and regional Hood models and algorithms. This also requires a considerable amount of training and capacity building for the RCMRD experts who will help us validate the model results and eventually transition it for operational use. In a final analysis, Disaster management and humanitarian aid organizations need accurate and timely information for making decisions regarding deployment of relief teams and emergency supplies during major floods. Flood maps based on the use of satellite data have proven extremely valuable to such organizations for identifying the location, extent, and severity of these events. However, despite extraordinary efforts on the part of remote sensing data providers to rapidly deliver such maps, there is typically a delay of several days or even weeks from the on-set of flooding until such maps are available to the disaster management community. This paper summarizes efforts at NASA to address this problem through development of an integrated and automated process of a) flood forecasting b) flood detection, c) satellite data acquisition, d) rapid Hood mapping and distribution, and e) validation of Hood forecasting and detection products.

Habib, Shahid↗

Fault Management Technology Maturation for NASA's Constellation Program

This slide presentation reviews the maturation of fault management technology in preparation for the Constellation Program. There is a review of the Space Shuttle Main Engine (SSME) and a discussion of a couple of incidents with the shuttle main engine and tanking that indicated the necessity for predictive maintenance. Included is a review of the planned Ares I-X Ground Diagnostic Prototype (GDP) and further information about detection and isolation of faults using Testability Engineering and Maintenance System (TEAMS). Another system that being readied for use that detects anomalies, the Inductive Monitoring System (IMS). The IMS automatically learns how the system behaves and alerts operations it the current behavior is anomalous. The comparison of STS-83 and STS-107 (i.e., the Columbia accident) is shown as an example of the anomaly detection capabilities.

Waterman, Robert D.↗

Athena

The Athena simulation software supports an analyst from DoD or other federal agency in making stability and reconstruction projections for operational analyses in areas like Iraq or Afghanistan. It encompasses the use of all elements of national power: diplomatic, information, military, and economic (DIME), and anticipates their effects on political, military, economic, social, information, and infrastructure (PMESII) variables in real-world battle space environments. Athena is a stand-alone model that provides analysts with insights into the effectiveness of complex operations by anticipating second-, third-, and higher-order effects. For example, the first-order effect of executing a curfew may be to reduce insurgent activity, but it may also reduce consumer spending and keep workers home as second-order effects. Reduced spending and reduced labor may reduce the gross domestic product (GDP) as a third-order effect. Damage to the economy will have further consequences. The Athena approach has also been considered for application in studies related to climate change and the smart grid. It can be applied to any project where the impacts on the population and their perceptions are important, and where population perception is important to the success of the project.

Chamberlain, Robert G.↗

Mapping Threats to Agriculture in East Africa: Performance of MODIS Derived LST for Frost Identification in Kenya's Tea Plantations

Increased prevalence of weather related hazards in eastern Africa including drought, floods, hail and frost threatening agricultural productivity. Kenya is heavily dependent on agriculture for economic growth (FAO 2013); (1) Agriculture contributed 23.5% and 21.5% of GDP in 2009 and 2010 respectively, (2) Employment to half a million households of smallholders and 150,000 on large tea estates. Tea growing in Kenya depends on stability of the weather; (1) Weather is unpredictable, (2) Frost has contributed 30% of tea leaf losses, (3) Drought has contributed 14-30%, (4) The losses are experienced between January and march - frost and dry season.

remote sensing↗

Developing a Crop Mask for Agricultural Assessments in Kenya

Kenya relies on agricultural production for supporting local consumption and other processing value chains. The role of agriculture in supporting Kenya's economy is critical, with its contribution to the Gross Domestic product (GDP) estimated at over 277,000 Million in 2016. With changing climate in a rain-fed dependent agricultural production system, cropping zones are shifting and proper decision making will require updated data for proper delineation of cropping areas and extent; especially in agriculture and food security assessments. Where up-to-date data is not available it is important that it is generated and passed over to relevant stakeholders to inform their decision making processes. It is important that government agencies, non-governmental agencies and other agricultural stakeholders access updated tools and information to assist in their assessments. To support agricultural decision making, SERVIR E&SA will develop an updated agricultural crop mask. Due to intercropping especially in small holder farming, the mask will cover all crops to provide an overall map of cropped areas.

environment↗

Ground Delay Program Analytics with Behavioral Cloning and Inverse Reinforcement Learning

We used historical data to build two types of model that predict Ground Delay Program implementation decisions and also produce insights into how and why those decisions are made. More specifically, we built behavioral cloning and inverse reinforcement learning models that predict hourly Ground Delay Program implementation at Newark Liberty International and San Francisco International airports. Data available to the models include actual and scheduled air traffic metrics and observed and forecasted weather conditions. We found that the random forest behavioral cloning models we developed are substantially better at predicting hourly Ground Delay Program implementation for these airports than the inverse reinforcement learning models we developed. However, all of the models struggle to predict the initialization and cancellation of Ground Delay Programs. We also investigated the structure of the models in order to gain insights into Ground Delay Program implementation decision making. Notably, characteristics of both types of model suggest that GDP implementation decisions are more tactical than strategic: they are made primarily based on conditions now or conditions anticipated in only the next couple of hours.

Bloem, Michael↗

Reductions in NO2 Burden Over North Equatorial Africa from Decline in Biomass Burning in Spite of Growing Fossil Fuel Use, 2005 to 2017

Socioeconomic development in low- and middle-income countries has been accompanied by increased emissions of air pollutants, such as nitrogen oxides [NOx: nitrogen dioxide (NO2) + nitric oxide (NO)], which affect human health. In sub-Saharan Africa, fossil fuel combustion has nearly doubled since 2000. At the same time, landscape biomass burning—another important NOx source—has declined in north equatorial Africa, attributed to changes in climate and anthropogenic fire management. Here, we use satellite observations of tropospheric NO2 vertical column densities (VCDs) and burned area to identify NO2 trends and drivers over Africa. Across the northern ecosystems where biomass burning occurs—home to hundreds of millions of people—mean annual tropospheric NO2 VCDs decreased by 4.5% from 2005 through 2017 during the dry season of November through February. Reductions in burned area explained the majority of variation in NO2 VCDs, though changes in fossil fuel emissions also explained some variation. Over Africa’s biomass burning regions, raising mean GDP density (USD·km−2) above its lowest levels is associated with lower NO2 VCDs during the dry season, suggesting that economic development mitigates net NO2 emissions during these highly polluted months. In contrast to the traditional notion that socioeconomic development increases air pollutant concentrations in low- and middle-income nations, our results suggest that countries in Africa’s northern biomass-burning region are following a different pathway during the fire season, resulting in potential air quality benefits. However, these benefits may be lost with increasing fossil fuel use and are absent during the rainy season.

air pollution↗

Bhutan Agriculture II: Creating a Graphical User Interface, Crop Mask, and Data Collection Protocol for Analysis of Rice Crop in Bhutan Using Remotely Sensed Data

Agriculture is an important sector in Bhutan, accounting for 19.63% of Bhutan’s GDP in 2020 (World Bank) while also providing livelihoods for approximately 57% of the population (World Bank, 2017). The Department of Agriculture (DoA) in Bhutan still relies on in-field reporting for crop monitoring, which is time-consuming and labour intensive. To promote efficiency in these efforts, the team partnered with the DoA, the Bhutan Foundation, and the Ugyen Wangchuck Institute of Conservation and Environmental Research (UWICER). The team, with the help of the science advisors from NASA SERVIR, expanded the crop mask created in the previous term to the whole country of Bhutan and streamlined the sampling protocols for applicability to any available crop data. The team also created a graphical user interface (GUI) which provided a visual representation of current trends and rice distribution across Bhutan. The team utilized NASA Earth observations, including Landsat 5 Thematic Mapper (TM), Landsat 7 Enhanced Thematic Mapper Plus (ETM+), Landsat 8 Operational Land Imager (OLI), and Shuttle Radar Topography Mission (SRTM), as well as other Earth observations including Sentinel-1 C-band Synthetic Aperture Radar (C-SAR). This project refined the previous term’s methodology to help supplement crop monitoring and increase the frequency of data collected to aid decision-making processes with the use of remote sensing data.

Wangdrak Dorji​↗

Spatial and Temporal Analysis of Global Landslide Reporting Using a Decade of the Global Landslide Catalog

Rainfall-triggered landslides can result in devastating loss of life and property damage and are a growing concern from local to global scale. NASA’s Global Landslide Catalog (GLC) compiles a record of rainfall-triggered landslide events from media reports, academic articles, and existing databases at global scale. The database consists of all types of mass movement events that are triggered by rainfall and represents a minimum number of events occurring between 2007 – 2018. The research presented here evaluates global patterns in landslide reporting from events in the GLC. The evaluation includes an analysis of the spatial and temporal distribution of global landslide events and associated casualties and comparisons with other landslide inventories. This database has been used to estimate landslide hotspots, evaluate geographic patterns in landslides, and train and validate landslide models from local to global scales. The most notable landslide hotspots are in the Pacific Northwest of North America, High Mountain Asia, and the Philippines. Additionally, the relationship between country GDP and income status with landslide occurrence was determined to have a positive correlation between economic status and landslide reporting. The GLC also indicates a reporting bias towards English-speaking countries. The general goal of this research is to assess the decade of global landslide reports from the GLC and show how this database can be used for rainfall-triggered landslide research.

Global Landslide Catalog↗

Predicting Air Traffic Management Initiatives Using Supervised Learning

Terminal Traffic Management Initiatives (TMIs) such as Ground Stops (GS) and Ground Delay Programs (GDP) are implemented to manage excess demand or lowered capacity at an airport. Air Traffic Flow Management (TFM) specialists identify situations such as aviation constraints, current and forecasted weather conditions, airport demand and capacity, and initiate TMIs for safe and orderly movement of air traffic. In this paper, we outline supervised learning techniques that can be used to predict and recommend TMIs at an airport based on current weather and airport conditions. Our research involves building classic Machine Learning (ML) models such as Logistic Regression, K-Nearest Neighbor, Random Forest and XGBoost, as well as Long short-term memory (LSTM) networks. We trained the models on 3-year historical data (weather, airport demand, capacity and TMIs) from Newark (EWR) airport which was selected based on its higher TMI implementation rates and varied weather conditions. Although Random Forest and XGBoost algorithms are able to predict if a TMI is needed or not, they have difficulty in predicting specific program type. For this purpose, we found that LSTM time-series forecasting models performed better as they also learn from past TMI program type sequences. This study also lays down the foundation for advanced modeling techniques and architectures to predict TMIs in advance for future periods. The ability to predict TMIs in advance will be highly beneficial to the traffic controllers and managers as this will help them to prepare for and manage TMIs more efficiently.

Manoj Agrawal↗