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Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease

The RNA and DNA tumor viruses have made fundamental contributions to two major areas of cancer research. Viruses were vital, first, to the discovery and analysis of cellular growth control pathways and the synthesis of current concepts of cancer biology and, second, to the recognition of the etiology of some human cancers. Transforming retroviruses carry oncogenes derived from cellular genes that are involved in mitogenic signalling and growth control. DNA tumor viruses encode oncogenes of viral origin that are essential for viral replication and cell transformation; viral oncoproteins complex with cellular proteins to stimulate cell cycle progression and led to the discovery of tumor suppressors. Viral systems support the concept that cancer development occurs by the accumulation of multiple cooperating events. Viruses are now accepted as bona fide etiologic factors of human cancer; these include hepatitis B virus, Epstein-Barr virus, human papillomaviruses, human T-cell leukemia virus type I and hepatitis C virus, plus several candidate human cancer viruses. It is estimated that 15% of all human tumors worldwide are caused by viruses. The infectious nature of viruses distinguishes them from all other cancer-causing factors; tumor viruses establish long-term persistent infections in humans, with cancer an accidental side effect of viral replication strategies. Viruses are usually not complete carcinogens, and the known human cancer viruses display different roles in transformation. Many years may pass between initial infection and tumor appearance and most infected individuals do not develop cancer, although immunocompromised individuals are at elevated risk of viral-associated cancers. Variable factors that influence viral carcinogenesis are reviewed, including possible synergy between viruses and environmental cofactors. The difficulties in establishing an etiologic role for a virus in human cancer are discussed, as well as the different approaches that proved viral links to cancer. Future directions for tumor virus studies are considered.

NASA Program Biomedical Research and Countermeasur↗

Global Geospace Science (GGS)/POLAR Thermal Ion Dynamics Experiments (TIDE) Co-Investigator Program: Mission Operations and Data Analysis (MO/DA)

We have pursued several investigations using the Polar/TIDE data set. The first was a comparison of TIDE high-altitude observations with similar ion flux signatures in the Los Alamos National Laboratory (LANL) magnetospheric plasma analyzer (MPA) data. There are several geosynchronously orbiting satellites with LANL MPA instruments onboard. When the satellite is immersed in fresh plasma sheet electrons, the spacecraft voltage drops to several hundred volts negative, and cold ions are accelerated in to the detector. In the LANL MPA spectrograms, the accelerated cold ions appear as a bright, narrow line, following the voltage of the spacecraft. This "ion line" is seen regularly on the nightside, but has not received much attention. The Polar TIDE observations indicated a ubiquitous "lobal wind" in the near-- magnetotail, a field-aligned stream of approx. 100 eV ions flowing out of both polar ionospheres. The interesting result of this research is that the MPA ion line is also peaked in the field-aligned direction, even though the potential well should be uniform in all directions. It is believed that this is evidence that the lobal winds not only populate the high-latitude lobes, but fill the lobes all the way in to the near-Earth plasma sheet (the location of geosynchronous orbit). This activity developed into a full-scale survey of the lobal wind observations in the TIDE database. The universality of these observations with respect to local time and solar wind conditions implies that the ionospheric outflow is supplying the near-Earth plasma sheet at all times, regardless of magnetic activity. We have conducted a statistical study of the characteristics of the lobal wind in these two data sets FIDE and LANL MPA), finding much similarity between them. Using these characteristics as input conditions to our inner magnetosphere ion transport model, we have conducted simulations of the flow of these particles inside of geosynchronous orbit to show the impact these particles will have on the near-Earth space environment. As the study has progressed, these results have been presented several times to the TIDE team during teleconferences. It is planned to present this survey at the GEM 2004 Summer Workshop, and hopefully at additional conferences in the near future. We are presently writing a paper on the lobal wind occurrence statistics, which should be submitted in April or May to the Journal of Geophysical Research for publication. An undergraduate student at the University of Alabama in Huntsville, Will Maddox, working at NASA MSFC with Dr. Paul Craven, is presently creating a database of the values TIDE moments for the lobal wind (under Dr. Liemohn's guidance), and this will be the focus of a follow-on paper.

Nagy, Andrew↗

Chandra Observations of NGC 4698: A Seyfert 2 Galaxy with No Absorption

We present Chandra ACIS-S observations of the enigmatic Seyfert 2 galaxy NGC 4698. This object, together with several other bona fide Seyfert 2 galaxies, shows no absorption in the low spatial resolution ASCA data, in contrast to the standard unification models. Our Chandra observations of NGC 4698 probe directly the nucleus, allowing us to check whether nearby sources contaminate the ASCA spectrum. Indeed, the Chandra observations show that the ASCA spectrum is dominated by two nearby AGNs. The X-ray flux of NGC 4698 is dominated by a nuclear source with luminosity L(sub 0.3-8 keV) approximately 10(exp 39) ergs per second, coincident with the radio nucleus. Its spectrum is well represented by a power law, GAMMA approximately equal to 2.2, obscured by a small column density of 5 x 10(exp 20) per square centimeter, suggesting that NGC 4698 is an atypical Seyfert galaxy. On the basis of its low luminosity, we then interpret NGC 4698 as a Seyfert galaxy that lacks a broad-line region.

Georgantopoulos, I.↗

A Scheme for finding the Front Boundary of an Interplanetary Magnetic Cloud

We developed a scheme for finding the front boundary of an interplanetary magnetic cloud (MC) based on criteria that depend on the possible existence of any one or all of six specific solar wind features. The features that the program looks for, within +/- 2 hours of a preliminarily determined time for the front boundary, estimated either by visual inspection or by an automatic MC identification scheme, are: (1) a sufficiently large directional discontinuity in the interplanetary magnetic field (IMF), (2) existence of a magnetic hole, (3) a significant proton plasma beta drop, (4) a significant proton temperature drop, (5) a marked increase in the IMF's intensity, and (6) a significant decrease in a normalized root-mean-square deviation (RMS)of the magnetic field - where the scheme was tested using 5, 10, 15, and 20 minute averages of the relevant physical quantities, in order to find the optimum average (and RMS) to use. Other criteria, besides these six, were examined and dismissed as not reliable, e.g., plasma speed. The scheme was developed specifically for aiding in forecasting the strength and timing of a geomagnetic storm due to the passage of an interplanetary MC in real-time, but can be used in post ground-data collection for imposition of consistency in choosing a MC's front boundary. The scheme has been extensively tested, first using 80 bona fide MCs over about 9 years of WIND data, and also for 121 MC-like structures as defined by a program that automatically identifies such structures over the same period. Optimum limits for various parameters in the scheme were found by statistical studies of the WIND MCs. The resulting limits can be user-adjusted for other data sets, if desired. Final testing of the 80 MCs showed that for 50 percent of the events the boundary estimates occurred within +/-10 minutes of visually determined times, 80 percent occurred within +/-30 minutes, and 91 percent occur within +/-60 minutes, and three or more individual boundary tests were passed for 88 percent of the total MCs. The scheme and its testing will be described.

Lepping, Ronald P.↗

The Role of Evolutionary Age and Metallicity in the Formation of Classical BE Circumstellar Disks II. Assessing the True Nature of Candidate Disk Systems

Photometric 2-color diagram (2-CD) surveys of young cluster populations have been used to identify populations of B-type stars exhibiting excess Ha emission. The prevalence of these excess emitters, assumed to be "Be stars". has led to the establishment of links between the onset of disk formation in classical Be stars and cluster age and/or metallicity. We have obtained imaging polarization observations of six SMC and six LMC clusters whose candidate Be populations had been previously identified via 2-CDs. The interstellar polarization (ISP) associated with these data has been identified to facilitate an examination of the circumstellar environments of these candidate Be stars via their intrinsic polarization signatures, hence determine the true nature of these objects. We determined that the ISP associated with the SMC cluster NGC 330 was characterized by a modified Serkowski law with a lambda(sub max) of approx. 4500Angstroms, indicating the presence of smaller than average dust grains. The morphology of the ISP associated with the LMC cluster NGC 2100 suggests that its interstellar environment is characterized by a complex magnetic field. Our intrinsic polarization results confirm the suggestion of Wisniewski et al. that a substantial number of bona-fide classical Be stars are present in clusters of age 5-8 Myr. Hence, our data contradict recent assertions that the Be phenomenon develops in the second half of a B star's main sequence lifetime, i.e. no earlier than 10 Myr. These data imply that a significant number of B-type stars must emerge onto the zero-age-main-sequence rotating at near-critical rotation rates, although we can not rule out the possibility that these data instead reveal the presence of a sub-group of the Be phenomenon characterized by sub-critically rotating objects. Comparing the polarimetric properties of our dataset to a similar survey of Galactic classical Be stars, we find that the prevalence of polarimetric Balmer jump signatures decreases with metallicity. We speculate that these results might indicate that either it is more difficult to form large disk systems in low metallicity environments, or that the average disk temperature is higher in these low metallicity environments. We have characterized the polarimetric signatures of all candidate Be stars in our data sample and find approx. 25% are unlikely to arise from true classical Be star-disk systems. This detection of such a substantial number "contaminants" suggests one should proceed with caution when attempting to determine the role of evolutionary age and/or metallicity in the Be phenomenon purely via 2-CD results.

Wisniewski, J. P.↗

The Search for Interstellar Sulfide Grains

The lifecycle of sulfur in the galaxy is poorly understood. Fe-sulfide grains are abundant in early solar system materials (e.g. meteorites and comets) and S is highly depleted from the gas phase in cold, dense molecular cloud environments. In stark contrast, sulfur is essentially undepleted from the gas phase in the diffuse interstellar medium, indicating that little sulfur is incorporated into solid grains in this environment. It is widely believed that sulfur is not a component of interstellar dust grains. This is a rather puzzling observation unless Fe-sulfides are not produced in significant quantities in stellar outflows, or their lifetime in the ISM is very short due to rapid destruction. Fe sulfide grains are ubiquitous in cometary samples where they are the dominant host of sulfur. The Fe-sulfides (primarily pyrrhotite; Fe(1-x)S) are common, both as discrete 0.5-10 micron-sized grains and as fine (5-10 nm) nanophase inclusions within amorphous silicate grains. Cometary dust particles contain high abundances of well-preserved presolar silicates and organic matter and we have suggested that they should contain presolar sulfides as well. This hypothesis is supported by the observation of abundant Fe-sulfides grains in dust around pre- and post-main sequence stars inferred from astronomical spectra showing a broad 23 micron IR feature due to FeS. Fe-sulfide grains also occur as inclusions in bona fide circumstellar amorphous silicate grains and as inclusions within deuterium-rich organic matter in cometary dust samples. Our irradiation experiments show that FeS is far more resistant to radiation damage than silicates. Consequently, we expect that Fe sulfide stardust should be as abundant as silicate stardust in solar system materials.

Keller, Lindsay P.↗

Crystallization of Yamato 980459 at 0.5 GPA: Are Residual Liquids Like QUE 94201?

The Martian basaltic meteorites Y980459 and QUE94201 (henceforth referred to as Y98 and QUE respectively) are thought to represent magmatic liquid compositions, rather than being products of protracted crystallization and accumulation like the majority of other martian meteorites. Both meteorite compositions have been experimentally crystallized at 1 bar, and liquidus phases were found to match corresponding mineral core compositions in the meteorites, consistent with the notion that these meteorites represent bona fide melts. They also represent the most primitive and most evolved basaltic martian samples, respectively. Y98 has Mg# (molar Mg/Mg+Fe) approximates 65, and lacks plagioclase; whereas QUE has Mg# approximates 40, and lacks olivine. However they share important geochemical characteristics (e.g. superchondritic CaO/Al2O3, very high epsilon(sub Nd) and low Sr-87/Sr-87) that suggest they sample a similar highly depleted mantle reservoir. As such, they represent likely endmembers of martian magmatic liquid compositions, and it is natural to seek petrogenetic linkages between the two. We make no claim that the actual meteorites themselves share a genetic link (the respective ages rule that out); we are exploring only in general whether primitive martian liquids like Y98 could evolve to liquids resembling QUE. Both experimental and computational efforts have been made to determine if there is indeed such a link. Recent petrological models at 1 bar generated using MELTS suggest that a QUE-like melt can be derived from a parental melt with a Y98 composition. However, experimental studies at 1 bar have been less successful at replicating this progression. Previous experimental crystallization studies of Y98 by our group at 0.5 GPa have produced melt compositions approaching that of QUE, although these results were complicated by the presence of small, variable amounts of H2O in some of the runs owing to the use of talc/pyrex experimental assemblies. Therefore we have repeated the four experiments, augmented with additional runs, all using BaCO3 cell assemblies, which are devoid of water, and these new experiments supersede those reported earlier. Here we report results of experiments simulating equilibrium crystallization; fractional crystallization experiments are currently underway.

Rapp, J. F.↗

WISE Detections of Dust in the Habitable Zones of Planet-Bearing Stars

We use data from the Wide-field Infrared Survey Explorer (WISE) all-sky release to explore the incidence of warm dust in the habitable zones around exoplanet-host stars. Dust emission at 12 and/or 22 microns (T(sub dust) approx.300 and/or approx.150 K) traces events in the terrestrial planet zones; its existence implies replenishment by evaporation of comets or collisions of asteroids, possibly stirred by larger planets. Of the 591 planetary systems (728 extrasolar planets) in the Exoplanet Encyclopedia as of 2012 January 31, 350 are robustly detected by WISE at > or = 5(sigma) level. We perform detailed photosphere subtraction using tools developed for Spitzer data and visually inspect all the WISE images to confirm bona fide point sources. We find nine planet-bearing stars show dust excess emission at 12 and/or 22 microns at > or = 3(sigma) level around young, main-sequence, or evolved giant stars. Overall, our results yield an excess incidence of approx.2.6% for stars of all evolutionary stages, but approx.1% for planetary debris disks around main-sequence stars. Besides recovering previously known warm systems, we identify one new excess candidate around the young star UScoCTIO 108.

Morales, Farisa Y.↗

What Are Space Exposure Histories Telling Us about CM Carbonaceous Chondrites?

Chondrites are chemically primitive and carbonaceous (C) chondrites are potentially the most primitive among them because they mostly escaped thermal metamor-phism that affected the other chondrite groups and ratios of their major, non-volatile and most of the volatile elements are similar to those of the Sun. Therefore, C chondrites are ex-pected to retain a good record of the origin and early history of the solar system. Carbonaceous chondrites are chemically differentiated from other chondrites by their high Mg/Si ratios and refractory elements, and have experienced various degrees of aqueous alteration. They are subdivided into eight subgroups (CI, CM, CO, CV, CK, CR, CB and CH) based on major element and oxygen isotopic ratios. Their elemental ratios spread over a wide range though those of ordinary and enstatite chondrites are relatively uniform. It is critical to know how many sepa-rate bodies are represented by the C chondrites. In this study, CM chondrites, the most abundant carbona-ceous chondrites, are examined. They are water-rich, chon-drule- and CAI-bearing meteorites and most of them are brec-cias. High-temperature components such as chondrules, iso-lated olivine and CAIs in CMs are frequently altered and some of them are replaced by clay minerals and surrounded by sul-fides whose Fe was derived from mafic silicates. On the basis of degrees of aqueous alteration, CMs have been classified into subtypes from 1 to 2, although Rubin et al. [1] assigned subtype 1 to subtype 2 and subtype 2 to subtype 2.6 using various petrologic properties. The classification is based on petrographic and mineralogic properties. For example, though tochilinite (2[(Fe, Mg, Cu, Ni[])S] 1.57-1.85 [(Mg, Fe, Ni, Al, Ca)(HH)2]) clumps are produced during aqueous alteration, they disappear and sulfide appears with increasing degrees of aqueous alteration. Cosmic-ray exposure (CRE) age measurements of CM chondrites reveal an unusual feature. Though CRE ages of other chondrite groups range from several Myr to tens of Myr, CMs exposure ages are not longer than 7 Myr with one-third of the CM having less than 1 Myr CRE age. For those CM chondrites that have CRE ages <1 Myr, there are two discern-able CRE peaks. Because a CRE age reflects how long a me-teorite is present as a separate body in space, the peaks pre-sumably represent collisional events on the parent body (ies) [2]. In this study we defined 4 distinct CRE age groups of CMs and systematically characterized the petrography in each of the 4 CRE age groups to determine whether the groups have significant petrographic differences, with such differences probably reflecting different parent body (asteroid) geological processing, or multiple original bodies.

Takenouchi, A.↗

Spindle-shaped Microstructures: Potential Models for Planktonic Life Forms on Other Worlds

Spindle-shaped, organic microstructures ("spindles") are now known from Archean cherts in three localities (Figs. 1-4): The ~3 Ga Farrel Quartzite from the Pilbara of Australia [1]; the older, ~3.3-3.4 Ga Strelley Pool Formation, also from the Pilbara of Australia [2]; and the ~3.4 Ga Kromberg Formation of the Barberton Mountain Land of South Africa [3]. Though the spindles were previously speculated to be pseudofossils or epigenetic organic contaminants, a growing body of data suggests that these structures are bona fide microfossils and further, that they are syngenetic with the Archean cherts in which they occur [1-2, 4-10]. As such, the spindles are among some of the oldest-known organically preserved microfossils on Earth. Moreover, recent delta C-13 study of individual spindles from the Farrel Quartzite (using Secondary Ion Mass Spectrometry [SIMS]) suggests that the spindles may have been planktonic (living in open water), as opposed to benthic (living as bottom dwellers in contact with muds or sediments) [9]. Since most Precambrian microbiotas have been described from benthic, matforming communities, a planktonic lifestyle for the spindles suggests that these structures could represent a segment of the Archean biosphere that is poorly known. Here we synthesize the recent work on the spindles, and we add new observations regarding their geographic distribution, robustness, planktonic habit, and long-lived success. We then discuss their potential evolutionary and astrobiological significance.

Oehler, Dorothy Z.↗

On the Weak-Wind Problem in Massive Stars: X-Ray Spectra Reveal a Massive Hot Wind in mu Columbae

Mu Columbae is a prototypical weak-wind O star for which we have obtained a high-resolution X-ray spectrum with the Chandra LETG/ACIS instrument and a low-resolution spectrum with Suzaku. This allows us, for the first time, to investigate the role of X-rays on the wind structure in a bona fide weak-wind system and to determine whether there actually is a massive hot wind. The X-ray emission measure indicates that the outflow is an order of magnitude greater than that derived from UV lines and is commensurate with the nominal wind-luminosity relationship for O stars. Therefore, the "weak-wind problem"--identified from cool wind UV/optical spectra--is largely resolved by accounting for the hot wind seen in X-rays. From X-ray line profiles, Doppler shifts, and relative strengths, we find that this weak-wind star is typical of other late O dwarfs. The X-ray spectra do not suggest a magnetically confined plasma-the spectrum is soft and lines are broadened; Suzaku spectra confirm the lack of emission above 2 keV. Nor do the relative line shifts and widths suggest any wind decoupling by ions. The He-like triplets indicate that the bulk of the X-ray emission is formed rather close to the star, within five stellar radii. Our results challenge the idea that some OB stars are "weak-wind" stars that deviate from the standard wind-luminosity relationship. The wind is not weak, but it is hot and its bulk is only detectable in X-rays.

Weak-wind↗

The 60 Month All-Sky Burst Alert Telescope Survey of Active Galactic Nucleus and the Anisotropy of Nearby AGNs

Surveys above 10 keV represent one of the best resources to provide an unbiased census of the population of active galactic nuclei (AGNs). We present the results of 60 months of observation of the hard X-ray sky with Swift/Burst Alert Telescope (BAT). In this time frame, BAT-detected (in the 15-55 keV band) 720 sources in an all-sky survey of which 428 are associated with AGNs, most of which are nearby. Our sample has negligible incompleteness and statistics a factor of approx. 2 larger over similarly complete sets of AGNs. Our sample contains (at least) 15 bona fide Compton-thick AGNs and 3 likely candidates. Compton-thick AGNs represent approx. 5% of AGN samples detected above 15 keV. We use the BAT data set to refine the determination of the log N-log S of AGNs which is extremely important, now that NuSTAR prepares for launch, toward assessing the AGN contribution to the cosmic X-ray background. We show that the log N-log S of AGNs selected above 10 keV is now established to approx. 10% precision. We derive the luminosity function of Compton-thick AGNs and measure a space density of 7.9(+4.1/−2.9)× 10(exp −5)/cubic Mpc for objects with a de-absorbed luminosity larger than 2 × 10(exp 42) erg / s. As the BAT AGNs are all mostly local, they allow us to investigate the spatial distribution of AGNs in the nearby universe regardless of absorption. We find concentrations of AGNs that coincide spatially with the largest congregations of matter in the local (much < 85 Mpc) universe. There is some evidence that the fraction of Seyfert 2 objects is larger than average in the direction of these dense regions..

SURVEY↗

iPTF14yb: The First Discovery of a Gamma-Ray Burst Afterglow Independent of a High-Energy Trigger

We report here the discovery by the Intermediate Palomar Transient Factory (iPTF) of iPTF14yb, a luminous (Mr >> -27.8 mag), cosmological (redshift 1.9733), rapidly fading optical transient. We demonstrate, based on probabilistic arguments and a comparison with the broader population, that iPTF14yb is the optical afterglow of the long-duration gamma-ray burst GRB 140226A. This marks the first unambiguous discovery of a GRB afterglow prior to (and thus entirely independent of) an associated high-energy trigger. We estimate the rate of iPTF14yb-like sources (i.e., cosmologically distant relativistic explosions) based on iPTF observations, inferring an all-sky value of Rrel = 610/yr (68% confidence interval of 110-2000/yr). Our derived rate is consistent (within the large uncertainty) with the all-sky rate of on-axis GRBs derived by the Swift satellite. Finally, we briefly discuss the implications of the nondetection to date of bona fide "orphan" afterglows (i.e., those lacking detectable high-energy emission) on GRB beaming and the degree of baryon loading in these relativistic jets.

gamma-ray burst: general aEuro" stars: flare aEuro↗

Laboratory Analysis of Silicate Stardust Grains of Diverse Stellar Origins

Silicate dust is ubiquitous in a multitude of environments across the cosmos, including evolved oxygen-rich stars, interstellar space, protoplanetary disks, comets, and asteroids. The identification of bona fide silicate stardust grains in meteorites, interplanetary dust particles, micrometeorites, and dust returned from comet Wild 2 by the Stardust spacecraft has revolutionized the study of stars, interstellar space, and the history of dust in the Galaxy. These stardust grains have exotic isotopic compositions that are records of nucleosynthetic processes that occurred in the depths of their now extinct parent stars. Moreover, the chemical compositions and mineralogies of silicate stardust are consequences of the physical and chemical nature of the stellar condensation environment, as well as secondary alteration processes that can occur in interstellar space, the solar nebula, and on the asteroid or comet parent body in which they were incorporated. In this talk I will discuss our use of advanced nano-scale instrumentation in the laboratory to conduct coordinated isotopic, chemical, and mineralogical analyses of silicate stardust grains from AGB stars, supernovae, and novae. By analyzing the isotopic compositions of multiple elements in individual grains, we have been able to constrain their stellar sources, explore stellar nucleosynthetic and mixing processes, and Galactic chemical evolution. Through our mineralogical studies, we have found these presolar silicate grains to have wide-ranging chemical and mineral characteristics. This diversity is the result of primary condensation characteristics and in some cases secondary features imparted by alteration in space and in our Solar System. The laboratory analysis of actual samples of stars directly complements astronomical observations and astrophysical models and offers an unprecedented level of detail into the lifecycles of dust in the Galaxy.

Nguyen, Ann N.↗

The Caltech-NRAO Stripe 82 Survey (CNSS) Paper. I. The Pilot Radio Transient Survey in 50 Deg.(exp. 2)

We have commenced a multiyear program, the Caltech-NRAO Stripe 82 Survey (CNSS), to search for radio transients with the Jansky VLA in the Sloan Digital Sky Survey Stripe 82 region. The CNSS will deliver five epochs over the entire approx. 270 deg.(exp. 2) of Stripe 82, an eventual deep combined map with an rms noise of approx. 40 proper motion epoch y and catalogs at a frequency of 3 GHz, and having a spatial resolution of 3 inches. This first paper presents the results from an initial pilot survey of a 50 deg.(exp. 2) region of Stripe 82, involving four epochs spanning logarithmic timescales between 1 week and 1.5 yr, with the combined map having a median rms noise of 35 proper motion epoch y. This pilot survey enabled the development of the hardware and software for rapid data processing, as well as transient detection and follow-up, necessary for the full 270 deg.(exp. 2) survey. Data editing, calibration, imaging, source extraction, cataloging, and transient identification were completed in a semi-automated fashion within 6 hr of completion of each epoch of observations, using dedicated computational hardware at the NRAO in Socorro and custom-developed data reduction and transient detection pipelines. Classification of variable and transient sources relied heavily on the wealth of multiwavelength legacy survey data in the Stripe 82 region, supplemented by repeated mapping of the region by the Palomar Transient Factory. A total of 3.9(+0.5%/-0.9%) of the few thousand detected point sources werefound to vary by greater than 30%, consistent with similar studies at 1.4 and 5 GHz. Multiwavelength photometric data and light curves suggest that the variability is mostly due to shock-induced flaring in the jets of active galactic nuclei (AGNs). Although this was only a pilot survey, we detected two bona fide transients, associated with an RS CVn binary and a dKe star. Comparison with existing legacy survey data (FIRST, VLA-Stripe 82) revealed additional highly variable and transient sources on timescales between 5 and 20 yr, largely associated with renewed AGN activity. The rates of such AGNs possibly imply episodes of enhanced accretion and jet activity occurring once every approx. 40,000 yr in these galaxies. We compile the revised radio transient rates and make recommendations for future transient surveys and joint radio-optical experiments.

galaxies: active – radio continuum: galaxies –↗

The Weak Fe Fluorescence Line and Long-Term X-Ray Evolution of the Compton-Thick Active Galactic Nucleus in NGC7674

We present NuSTAR X-ray observations of the active galactic nucleus (AGN) in NGC7674.The source shows a flat X-ray spectrum, suggesting that it is obscured by Compton-thick gas columns. Based upon long-term flux dimming, previous work suggested the alternate possibility that the source is a recently switched-off AGN with the observed X-rays being the lagged echo from the torus. Our high-quality data show the source to be reflection-dominated in hard X-rays, but with a relatively weak neutral Fe K(alpha) emission line (equivalent width [EW] of approximately 0.4 keV) and a strong Fe XXVI ionized line (EW approximately 0.2 keV).We construct an updated long-term X-ray light curve of NGC7674 and find that the observed 2-10 keV flux has remained constant for the past approximately 20 yr, following a high-flux state probed by Ginga. Light travel time arguments constrain the minimum radius of the reflector to be approximately 3.2 pc under the switched-off AGN scenario, approximately 30 times larger than the expected dust sublimation radius, rendering this possibility unlikely. A patchy Compton-thick AGN (CTAGN) solution is plausible, requiring a minimum line-of-sight column density (N(sub H)) of 3 x 10(exp 24) cm(exp -2) at present, and yields an intrinsic 2-10 keV luminosity of (3-5) x 10(exp 43) erg s(exp -1). Realistic uncertainties span the range of approximately (1-13) x 10(exp 43) erg s1. The source has one of the weakest fluorescence lines amongst bona fide CTAGN, and is potentially a local analogue of bolometrically luminous systems showing complex neutral and ionized Fe emission. It exemplifies the difficulty of identification and proper characterization of distant CTAGN based on the strength of the neutral Fe K line

galaxies: Seyfert –X-rays: individual (NGC 7674)↗

Transiting Planets from Kepler, K2 & TESS

NASA's Kepler spacecraft, launched in 2009, has been a resounding success. More than 4000 planet candidates have been identified using data from Kepler primary mission, which ended in 2013, and greater than 2000 of these candidates have been verified as bona fide exoplanets. After the loss of two reaction wheels ended the primary mission, the Kepler spacecraft was repurposed in 2014 to observe many fields on the sky for short periods. This new mission, dubbed K2, has led to the discovery of greater than 600 planet candidates, approximately 200 of which have been verified to date; most of these exoplanets are closer to us than the majority of exoplanets discovered by the primary Kepler mission. TESS, launching in 2018, will survey most of the sky for exoplanets, with emphasis on those orbiting nearby and/or bright host stars, making these planets especially well-suited for follow-up observations with other observatories to characterize atmospheric compositions and other properties. More than one-third of the planet candidates found by NASA's are associated with target stars that have more than one planet candidate, and such 'multis' account for the majority of candidates that have been verified as true planets. The large number of multis tells us that flat multiplanet systems like our Solar System are common. Virtually all of the candidate planetary systems are stable, as tested by numerical integrations that assume a physically motivated mass-radius relationship. Statistical studies performed on these candidate systems reveal a great deal about the architecture of planetary systems, including the typical spacing of orbits and flatness. The characteristics of several of the most interesting confirmed Kepler & K2 multi-planet systems will also be discussed.

Lissauer, Jack↗

Reflection-dominated Nuclear X-Ray Emission in the Early-Type Galaxy ESO 565 G019

We present the discovery of a reflection-dominated active galactic nucleus (AGN) in the early-type radio-quietgalaxy ESO 565G019 with Suzaku and SwiftBurst Alert Telescope. The source X-ray spectrum below 10 keVis characteristic of other Compton-thick (CT) AGNs, clearly showing an inverted continuum and prodigiousfluorescence iron emission above 3 keV. A Compton shoulder to the neutral Fe K line also appears to be present.There is evidence for long-term hard X-ray flux variability that we associate with changes in the intrinsic AGNpower law. More of such reflection-dominated AGNs should be uncovered in the near future with the increasedsensitivity of ongoing and new hard X-ray surveys. ESO 565G019 is hosted in an early-type galaxy whosemorphology has been variously classified as either type E or type S0. Only about 20 bona fide CT-AGNs have been identified in the local universe so far, and all exist in host galaxies with late Hubble types (S0 or later). CT columns of nuclear obscuring gas are uncommon in early-type galaxies in the local universe, so confirmation of the exact morphological class of ESO 565G019 is important. Infrared photometry also shows the presence of largequantities of cool dust in the host, indicative of significant ongoing star formation. ESO 565G019 may be the firstidentified local example of minor-merger-driven CT-AGN growth in an early-type host, or may be the result ofinteraction with its neighboring galaxy ESO 565G018 in a wide pair.

comparison↗