SANS-CNN: An automated machine learning technique for spaceflight associated neuro-ocular syndrome with astronaut imaging data
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Sharif Amit Kamran↗
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Monitoring of subsidence with UAVSAR on Sherman Island in California's Sacramento–San Joaquin Delta
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Priyanka Sharma↗
Surface Creep Rate of the Southern San Andreas Fault Modulated by Stress Perturbations From Nearby Large Events
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Xiaohua Xu↗
Evaluation of Vegetation Bias in InSAR Time Series for Agricultural Areas Within the San Joaquin Valley, CA
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Kelly R. Devlin↗
B Complex 5-Methyltetrahydrofolate, Riboflavin, Pyridoxine, and Methylcobalamin Supplementation as a Non-Mechanical Countermeasure to Mitigate Optic Disc Edema Changes During Strict 6º Head-Down Tilt Bed Rest
A subset of astronauts on International Space Station missions have experienced optic disc edema, part of what is characterized as Spaceflight Associated Neuro-ocular Syndrome (SANS). While the precise cause of SANS is unknown, it is likely that there are multiple contributing factors, including genetic and environmental factors. Our recent work has shown that crewmembers with SANS have higher concentrations of metabolic biomarkers of impairments in the one-carbon metabolic pathway compared to unaffected astronauts - before, during, and after f light (1). B-vitamin status and the presence of one-carbon pathway single nucleotide polymorphism (SNP) variants predicted the incidence of SANS pathologies, including optic disc edema (2). Specifically, the G allele of methionine synthase reductase (MTRR) A66G and the C allele of serine hydroxymethyltransferase-1 (SHMT1) C1420T were associated with increased incidence of SANS pathologies (2). In a recent 30-d bed rest head-down tilt study with 0.5% CO2 exposure, 5 of 11 subjects developed optic disc edema (4) and the same SHMT1 C1420T and MTRR A66G genetic variants were associated with a larger increase in total retina thickness, a quantitative measure of optic disc edema (5). We published a multi-hit hypothesis of how genetics represents an indispensable element of SANS, which is a multifactorial problem (6). In brief: endothelial dysfunction secondary to genetic, biochemical/nutritional, and physiological (e.g., cardiovascular/fluid shift) f actors could lead to optic disc edema and the other ocular changes that occur in SANS. We expanded this hypothesis to include the possibility that genetic effects on B-vitamin status can alter nitric oxide synthesis and oxidative stress in the endothelium. This in turn could alter the turnover of structural components of the sclera, making it more susceptible to pathologic changes when faced with stressors related to the unrelenting headward fluid shift that occurs in weightlessness and strict head-down tilt bed rest (5). If the relationships that we have observed in flight and ground-based research hold true for the SANS Countermeasure Study, these genetic factors could predict who will be more susceptible to the development of SANS, and more importantly could also provide countermeasure options. As has been shown extensively in the literature, vitamin supplementation can serve to overcome genetic hindrances to one-carbon biochemistry and vascular physiology. Thus, based on our findings, publications, and hypotheses, supported by extensive supporting literature, we had hoped to test in the SANS Countermeasure Study the efficacy of a bioactive B-vitamin complex as a countermeasure to optimize function of the one-carbon pathway and prevent or mitigate optic disc edema during strict 6-degree head down tilt bed rest, and ultimately in space f light. While the supplement is no longer planned to be tested in the SANS Countermeasure Study because of laws regulating supplementation studies like this costing much more than initially planned, we will assess the contribution of one-carbon pathway genetics and B-vitamin status to SANS risk.
S R Zwart↗
Identification and interpretation of tectonic features from ERTS-1 imagery
The author has identified the following significant results. ERTS-1 imagery shows that the southern segment of the San Gabriel fault which controls the west fork of the San Gabriel River is strikingly similar to the Mill Creek Fault in the San Bernardino Mountains. It has also been noted that there is a similarity between the Sierra Madre thrust zone of the San Gabriel Mountains to the Banning thrust of the San Bernardino Mountains. This suggests that the southern San Gabriel fault was once continuous with the Mill Creek fault. When the San Bernardino Mountain block is theoretically moved to the northwest along the San Jacinto fault so that the Mill Creek fault is aligned with the southern part of the San Gabriel fault, it was found that the four transverse fault segments become aligned with the Pinto Fault on the east and with the Raymond-Santa Monica Malibu Fault zone on the west. The reconstruction identifies a continuous zone of transverse faulting extending from the Colorado River Desert to the Pacific. It seems likely that the entire fault zone was once a continuous left-lateral shear. This Anacapa Shear has probably been subjected to a 50 km left lateral movement. This analysis strongly indicates that the tectonic history of the Transverse Range has been characterized by left lateral shear on transverse faults and right lateral shear on the San Andreas fault system.
Abdel-Gawad, M.↗
Spaceflight Associated Neuro-Ocular Syndrome: A Brief for Astronaut Candidates
INTRODUCTION: Spaceflight Associated Neuro-ocular Syndrome (SANS) was first described in 2011 as a clinical process involving degradation of visual acuity and structural changes of the eye when exposed to microgravity. This syndrome poses a risk to astronaut vision, safety, and mission performance, especially during extended-duration missions. The modern astronaut cohort is a diverse group of men and women including scientists, engineers, teachers, pilots, business professionals, and artists. Given their diverse backgrounds, it is imperative all crews are educated on SANS risks and potential countermeasures. This education must be comprehensive and easily understood, regardless of academic background or specific expertise. TOPIC: A PowerPoint was created to serve as a presentation and stand-alone educational aid for all astronaut candidates (ASCANS). This medium was chosen as it can be updated dynamically as new information emerges. The brief was split into sections to facilitate organized delivery of complex content in easy-to-understand components. Sections included descriptive statistics, signs and symptoms, outcomes, myths and ongoing research, countermeasures, ongoing surveillance, and unknown and future directions. More research is necessary in order to understand this syndrome, and without continued ASCAN participation in research, acquisition of data will not be possible. These efforts will become increasingly critical with deep space and exploration missions. APPLICATION: We recommend regular use of this brief for all ASCANS, and potentially veteran crewmembers, given the high risks and potentially poor outcomes associated with SANS. For ASCANS, recommendations include that this brief be provided at the start of their training, with a bi-annual refresher course for all astronauts. This ensures they are current on SANS information, given the dynamic nature of this syndrome. Additionally, this brief will be made available to all as a self-study aid, utilized as a refresher immediately prior to launch. It is anticipated that this brief will promote the health, safety, and wellbeing of professional and private crews alike, during and after long-duration spaceflight. RESOURCES: Brunstetter, T., Tarver, B., & Tsung, A. (2022, October). Spaceflight Associated Neuro-ocular Syndrome (Sans) and its Risk to Nasa Astronauts. JSC Aerospace Medicine Clerkship. Houston, TX; Lyndon B. Johnson Space Center. Laurie, S. S., Macias, B. R., Pardon, L. P., Brunstetter, T., Tarver, W. J., Gibson, C. R., Greenwald, S. H., Jasien, K. V., Mason, S., & Tsung, A. (2022). (rep.). Evidence Report: Risk of Spaceflight Associated Neuro-ocular Syndrome (SANS). Houston, TX: National Aeronautics and Space Administration. Mader, T. H., Gibson, C. R., Pass, A. F., Kramer, L. A., Lee, A. G., Fogarty, J., ... & Polk, J. D. (2011). Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight. Ophthalmology, 118(10), 2058-2069. LEARNING OBJECTIVES: • The audience will be able to describe current Spaceflight Associated Neuro-ocular Syndrome (SANS) findings, significance, and countermeasures. • The audience will understand the importance of astronauts’ familiarity with SANS prior to flying and the large risks associated with this syndrome. CME QUESTIONS (3 QUESTIONS, MULTIPLE CHOICE A-D): 1. What is the approximate prevalence rate of SANS in astronauts? A. 22% B. 50% C. 66% D. 80% Answer: C. 2. Which of the ocular findings are NOT associated with SANS? A. Optic disc edema B. Retinal detachment C. Globe flattening D. Chorioretinal folds Answer: B. 3. Which of the following diagnostic technologies are NOT available in-flight? A. Ocular ultrasound B. Retinal photography C. MRI Orbit D. Optical Coherence Tomography (OCT) Answer: C.
Sara Stroble Mason↗
Effect of Strict Head Down Tilt Bedrest on Pituitary Gland Height
BACKGROUND Pituitary gland deformity and loss of pituitary height have been identified in astronauts postflight, hypothesized to be related to increased intracranial pressure or intracranial pressure pulsatility exposure from prolonged weightlessness. Microgravity-induced chronic headward fluid shift has been suggested as a root cause of intracranial compliance changes leading to altered intracranial pressure dynamics. Elevated intracranial pressure or pressure pulsatility is theorized to promote the development of an arachnoid diverticulum, which herniates into the pituitary fossa via a defect in the diaphragma sellae compressing the pituitary gland. We aimed to determine if chronic headward fluid induced by strict head-down tilt bed rest (HDTBR) can cause similar quantitative changes in pituitary gland height. METHODS Control group data from two 6-degree HDTBR studies were analyzed (SANS CM and AGBRESA). The AGBRESA study collected MRI data at Baseline, 14 days into HDTBR (HDTBR-14), 52 days into HDTBR (HDTBR-52), and three days into Recovery (R+ 3) and included eight healthy adults (2 women), age = 33 ± 8 years. The SANS CM collected MRI data at Baseline, 15 days into HDTBR (HDTBR-15), 29 days into HDTBR (HDTBR-29), and 12 days into Recovery (R+12) and included twelve healthy adults (4 women), age = 34 ± 9 years. Pituitary gland height was evaluated using a sagittal, 3D T1-MPRAGE sequence obtained on a dedicated 3T Siemens Biograph MRI scanner using a 32-channel head coil. Following the reconstruction of a true orthogonal sagittal plane of the pituitary gland using a 3D multiplanar reconstruction tool (Horosproject.org), the anterior pituitary mid-gland height at the pituitary stalk level was quantified according to the methodology described by Kramer et al. . A paired t-test was used to evaluate changes from the baseline measurements. FINDINGS The mean height of the pituitary gland at baseline was 6.5 ± 1.7 mm (AGBRESA) and 5.7 ± 1.6 mm (SANS CM). From baseline measurements, the SANS CM STUDY data showed a decrease in mean pituitary height of 0.3 mm (p=.011) at HDTBR-15, 0.5 mm at HDTBR-29 (p<.001) and 0.2 mm at R+12 (p=.02). From baseline measurements, the AGBRESA data showed a decrease in mean pituitary height of 0.3 mm (p=.06) at HDTBR-14, 0.6 mm at HDTBR-52 (p<.002) and 0.2 mm at R+3 (p=.13). CONCLUSION HDTBR results in progressive loss of pituitary height, which is most severe with the longest HDTBR exposure. Early pituitary height loss was the same at HDTBR-14 (AGBRESA) and HDTBR-15 (SANS CM). Residual pituitary height loss was the same at R+12 and R+3 but only significant in the latter (SANS CM). The degree of pituitary height loss at HDTBR-52 replicates the 0.6 mm height loss found in long-duration astronauts after approximately six months of microgravity exposure (p<.01, preflight mean height=5.9 mm). The hormonal effects of pituitary height loss are unknown in astronauts and HDTBR subjects and should be investigated in future studies. Future work will examine the individual variability in the loss of pituitary gland height and whether those changes are associated with other SANS findings, such as optic disc edema.
L A Kramer↗
California coast nearshore processes study
The author has identified the following significant results. In the Santa Barbara Channel the effect of the California and the Anacapa Currents are clearly seen in image 1109-18073M. The large triangular shaped lobe of suspended particulate matter that stretches almost to Anacapa Island from the Ventura River area is disrupted approximately midchannel by the east-moving Anacapa Current. In the Point Conception area a lobe of suspended material approximately 20 miles long can be seen moving eastward as a result of the California Current. In the San Francisco Bay area the major results include the detection and delineation of the San Francisco Bay, the location and vector of suspended sediment in the San Francisco Bay, and the ability to differentiate morphologic units within the San Francisco Bay tidelands. Several densitometer line traces seaward of the Golden Gate Bridge on image 1075-18173-4 outline the San Francisco Bay and give evidence of good water penetration.
Pirie, D. M.↗
California coastal processes study: Skylab
The author has identified the following significant results. In San Pablo Bay, the patterns of dredged sediment discharges were plotted over a three month period. It was found that lithogenous particles, kept in suspension by the fresh water from the Sacramento-San Joaquin, were transported downstream to the estuarine area at varying rates depending on the river discharge level. Skylab collected California coastal imagery at limited times and not at constant intervals. Resolution, however, helped compensate for lack of coverage. Increased spatial and spectral resolution provided details not possible utilizing Landsat imagery. The S-192 data was reformatted; band by band image density stretching was utilized to enhance sediment discharge patterns entrainment, boundaries, and eddys. The 26 January 1974 Skylab 4 imagery of San Francisco Bay was taken during an exceptionally high fresh water and suspended sediment discharge period. A three pronged surface sediment pattern was visible where the Sacramento-San Joaquin Rivers entered San Pablo Bay through Carquinez Strait.
Pirie, D. M.↗
Fault tectonics and earthquake hazards in parts of southern California
The author has identified the following significant results. Four previously unknown faults were discovered in basement terrane of the Peninsular Ranges. These have been named the San Ysidro Creek fault, Thing Valley fault, Canyon City fault, and Warren Canyon fault. In addition fault gouge and breccia were recognized along the San Diego River fault. Study of features on Skylab imagery and review of geologic and seismic data suggest that the risk of a damaging earthquake is greater along the northwestern portion of the Elsinore fault than along the southeastern portion. Physiographic indicators of active faulting along the Garlock fault identifiable in Skylab imagery include scarps, linear ridges, shutter ridges, faceted ridges, linear valleys, undrained depressions and offset drainage. The following previously unrecognized fault segments are postulated for the Salton Trough Area: (1) An extension of a previously known fault in the San Andreas fault set located southeast of the Salton Sea; (2) An extension of the active San Jacinto fault zone along a tonal change in cultivated fields across Mexicali Valley ( the tonal change may represent different soil conditions along opposite sides of a fault). For the Skylab and LANDSAT images studied, pseudocolor transformations offer no advantages over the original images in the recognition of faults in Skylab and LANDSAT images. Alluvial deposits of different ages, a marble unit and iron oxide gossans of the Mojave Mining District are more readily differentiated on images prepared from ratios of individual bands of the S-192 multispectral scanner data. The San Andreas fault was also made more distinct in the 8/2 and 9/2 band ratios by enhancement of vegetation differences on opposite sides of the fault. Preliminary analysis indicates a significant earth resources potential for the discrimination of soil and rock types, including mineral alteration zones. This application should be actively pursued.
Merifield, P. M.↗
Palinspastic reconstruction of southeastern California and southwestern Arizona for the middle Miocene
A paleogeographic reconstruction of southeastern California and southwestern Arizona at 10 Ma was made based on available geologic and geophysical data. Clockwise rotation of 39 deg was reconstructed in the eastern Transverse Ranges, consistent with paleomagnetic data from late Miocene volcanic rocks, and with slip estimates for left-lateral faults within the eastern Transverse Ranges and NW-trending right lateral faults in the Mojave Desert. This domain of rotated rocks is bounded by the Pinto Mountain fault on the north. In the absence of evidence for rotation of the San Bernardino Mountains or for significant right slip faults within the San Bernardino Mountains, the model requires that the late Miocene Pinto Mountain fault become a thrust fault gaining displacement to the west. The Squaw Peak thrust system of Meisling and Weldon may be a western continuation of this fault system. The Sheep Hole fault bounds the rotating domain on the east. East of this fault an array of NW-trending right slip faults and south-trending extensional transfer zones has produced a basin and range physiography while accumulating up to 14 km of right slip. This maximum is significantly less than the 37.5 km of right slip required in this region by a recent reconstruction of the central Mojave Desert. Geologic relations along the southern boundary of the rotating domain are poorly known, but this boundary is interpreted to involve a series of curved strike slip faults and non-coaxial extension, bounded on the southeast by the Mammoth Wash and related faults in the eastern Chocolate Mountains. Available constraints on timing suggest that Quaternary movement on the Pinto Mountain and nearby faults is unrelated to the rotation of the eastern Transverse Ranges, and was preceded by a hiatus during part of Pliocene time which followed the deformation producing the rotation. The reconstructed Clemens Well fault in the Orocopia Mountains, proposed as a major early Miocene strand of the San Andreas fault, projects eastward towards Arizona, where early Miocene rocks and structures are continuous across its trace. The model predicts a 14 deg clockwise rotation and 55 km extension along the present trace of the San Andreas fault during late Miocene and early Pliocene time. Palinspastic reconstructions of the San Andreas system based on this proposed reconstruction may be significantly modified from current models.
Richard, Stephen M.↗
Global positioning system reoccupation of early triangulation sites - Tectonic deformation of the Southern Coast Ranges
We study tectonic deformation in the Southern Coast Range, California. We use triangulation and astronomic azimuth data collected since 1875, trilateration since 1970, and global positioning system data collected from 1986 to 1987. Two modeling techniques have been used. An elastic block-fault model is applied to study the tectonic motion of the San Andreas Fault and the San Gregorio-Hosgri Fault. Station velocities are modeled to study regional deformations. Results show that the regional deformation is predominantly controlled by deep strike-slip motion along the San Andreas Fault, at a rate of 33 +/- 2 mm/yr. Deep slip along the San Gregorio-Hosgri Fault is about 0-4 mm/yr, assuming a locked suit to a depth of 20 km. Convergence normal to the San Andreas Fault in the Southern Coast Ranges is not greater than 0.02 microrad/yr.
Shen, Zheng-Kang↗
Development of a Real-Time GPS/Seismic Displacement Meter: Applications to Civilian Infrastructure in Orange and Western Riverside Counties, California
We propose a three-year applications project that will develop an Integrated Real-Time GPS/Seismic System and deploy it in Orange and Western Riverside Counties, spanning three major strike-slip faults in southern California (San Andreas, San Jacinto, and Elsinore) and significant populations and civilian infrastructure. The system relying on existing GPS and seismic networks will collect and analyze GPS and seismic data for the purpose of estimating and disseminating real-time positions and total ground displacements (dynamic, as well as static) during all phases of the seismic cycle, from fractions of seconds to years. Besides its intrinsic scientific use as a real-time displacement meter (transducer), the GPS/Seismic System will be a powerful tool for local and state decision makers for risk mitigation, disaster management, and structural monitoring (dams, bridges, and buildings). Furthermore, the GPS/Seismic System will become an integral part of California's spatial referencing and positioning infrastructure, which is complicated by tectonic motion, seismic displacements, and land subsidence. Finally, the GPS/Seismic system will also be applicable to navigation in any environment (land, sea, or air) by combining precise real-time instantaneous GPS positioning with inertial navigation systems. This development will take place under the umbrella of the California Spatial Reference Center, in partnership with local (Counties, Riverside County Flood and Water Conservation District, Metropolitan Water District), state (Caltrans), and Federal agencies (NGS, NASA, USGS), the geophysics community (SCIGN/SCEC2), and the private sector (RBF Consulting). The project will leverage considerable funding, resources, and R&D from SCIGN, CSRC and two NSF-funded IT projects at UCSD and SDSU: RoadNet (Real-Time Observatories, Applications and Data Management Network) and the High Performance Wireless Research and Education Network (HPWREN). These two projects are funded to develop both the wireless networks and the integrated, seamless, and transparent information management system that will deliver seismic, geodetic, oceanographic, hydrological, ecological, and physical data to a variety of end users in real-time in the San Diego region. CSRC is interested in providing users access to real-time, accurate GPS data for a wide variety of applications including RTK surveying/GIS and positioning of moving platforms such as aircraft and emergency vehicles. SCIGN is interested in upgrading sites to high-frequency real-time operations for rapid earthquake response and GPS seismology. The successful outcome of the project will allow the implementation of similar systems elsewhere, particularly in plate boundary zones with significant populations and civilian infrastructure. CSRC would like to deploy the GPS/Seismic System in other parts of California, in particular San Diego, Los Angeles County and the San Francisco Bay Area.
Bock, Yehuda↗
Gravitational Influence on Intraocular Pressure: Implications for Spaceflight and Disease
Spaceflight-associated neuro-ocular syndrome (SANS) describes a series of morphologic and functional ocular changes in astronauts first reported by Mader and colleagues in 2011. SANS is currently clinically defined by the development of optic disc edema during prolonged exposure to the weightless (microgravity) environment, which currently occurs on International Space Station (ISS). However, as improvements in our understanding of the ocular changes emerge, the definition of SANS is expected to evolve. Other ocular SANS signs that arise during and after ISS missions include hyperopic shifts, globe flattening, choroidal/retinal folds, and cotton wool spots. Over the last 10 years, ~1 in 3 astronauts flying long-duration ISS missions have presented with ≥ 1 of these ocular findings. Commensurate with research that combines disparate specialties (vision biology and spaceflight medicine), lessons from SANS investigations may also yield insight into ground-based ocular disorders, such as glaucomatous optic neuropathy that may have the potential to lessen the burden of this irreversible cause of vision loss on Earth.
Episcleral venous pressure↗
Exploring Endothelial Function Risk Factors and Optic Disc Edema Changes During Strict 6º Head-Down Tilt Bed Rest
Approximately 20% of astronauts on International Space Station missions experience ophthalmic pathologies including optic disc edema, part of what is characterized as Spaceflight Associated Neuro-ocular Syndrome (SANS). While the cause of SANS is unknown, there are likely multiple contributing factors, including genetics, that may affect the response to spaceflight in affected individuals. B-vitamin status and the presence of specific one-carbon pathway single nucleotide polymorphism (SNP) alleles predicted the incidence of SANS pathologies in astronauts and in bed rest subjects. There are several hypotheses for how genetic variants could lead to SANS, specifically related to endothelial function. The biochemical pathway to which these genes are associated is intimately involved in maintaining endothelial function via nitric oxide synthase (eNOS) coupling and nitric oxide (NO) production. Furthermore, eNOS uncoupling can impair the functional status of the endothelial glycocalyx, which lines the entirety of the vascular lumen and affects endothelial function. Vascular distension, stasis and altered shear forces, which are associated with headward fluid shifts, may also contribute to glycocalyx dysfunction and shedding, resulting in endothelial dysfunction and increased vascular permeability and tissue edema, potentially contributing to optic nerve and optic disc edema in affected individuals. Given the findings relating genetics and the risk of optic disc edema in astronauts during flight and subjects during bed rest, further investigation is warranted. In this study, we will assess the same genetic variants in another bed rest study: AGBRESA. Some of the AGBRESA subjects developed optic disc edema, but their genetics have not been studied. Furthermore, we will test available urine samples from prior bed rest studies (VaPER and AGBRESA) for markers of glycocalyx degradation to expand our understanding of factors contributing to SANS.
S R Zwart↗
Evaluation of Human Spaceflight-Related Tissue Weight Relief Using Whole Body Finite Element Model Simulations
Tissue Weight Relief (TWR) is a physiological condition observed in human spaceflight. It not only impacts the injury biomechanics of soft tissue but also the physiological responses of the cardiovascular system both due to fluid redistribution and the effect of tissue-related transmural pressure on the large venous blood vessels. Understanding the effects of tissue weight relief is especially important because of the role it may play in understanding the cause of Space Associated Neuro-Ocular Syndrome (SANS). SANS can be characterized by a number of ocular changes which reduce visual acuity and SANS related symptoms occur in up to 51% of astronauts. A prevailing theory for the causation of SANS is that of headward (cephalad) fluid shift and a prolonged increase of Intracranial Pressure (ICP) similar to intracranial hypertension, which is not fully supported by the experimental data or astronaut symptom reporting. However, it is still believed that SANS is caused by a pressure change in the eye and the surrounding tissues. It has been proposed that TWR plays a substantial role in affecting internal pressures and fluid shifts in microgravity. In this effort, two whole-body Finite Element (FE) models – Elemance and THUMS – are used to ascertain the microgravity-associated TWR of the musculature surrounding the lower body veins. Elemance and THUMS are physics-based computational models that have been validated and verified for several automotive and domestic applications, and as such, can simulate the relief of soft tissue weight due to changes in the gravitation vector. Specifically, the current effort modeled the transition of the gravitational vector from 1G to 0G, applied across the whole-body model in a supine position. For each 1G to 0G transition simulation, the lower body vein’s transmural pressure-time profile was extracted and averaged around the anterior portion of the thigh muscle. The ascertained transmural pressure changes from 1G to 0G transition are given in Figure 1 for the Elemance and the THUMS FE models. The transmural pressure changes of 10 mmHg and 21 mmHg are in the same order of magnitude as Lu’s value of 44 mmHg. It is to be noted that Lu implemented a 0D to 1D lumped parameter model and the Elemance and THUMS are 3D higher order computational models. This proof-of-concept approach demonstrates that TWR pressure can be adequately estimated with in silico techniques however, further in silico investigations need to be conducted to address the unique contributions to the transmural pressure from each of the computational models.
Finite element modeling↗
Identification and interpretation of tectonic features from ERTS-1 imagery
The author has identified the following significant results. The transverse faults observed in the central Coast Ranges of California are believed to represent the remnants of a major system of shear faults older than the San Andreas system. The transverse shear system is believed to have developed in the Mesozoic when the Pacific Plate was advancing under the North American Plate. Shear faults thus developed due to unequal rates of underthrusting. This tectonic model indicates that the intrusive belt of the proto-Sierra Nevada and the belt of eugeosynclinal sedimentary belt (Franciscan group) which lay to the west were both subjected to regional left-handed shear. Later development of the San Andreas system as transform faults of the East Pacific Rise changes the tectonic style to right-lateral tangential. The model explains the peculiar distribution of the Franciscan rocks in the Diablo Range east of the San Andreas fault and in Santa Lucia Range west of Nacimiento fault and the presence of Sierra Nevada type granitic blocks in between the two faults in the Salinia block. This model is also consistent with an analysis of the Texas and Parras shears which indicates that the southwestern part of North America has been subjected to a major left-lateral regional shear before the development of the San Andreas fault system.
Abdel-Gawad, M.↗