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At least 343 records · Page 19

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NASA NTRS2020

Returning Samples from Enceladus for Life Detection

Evidence suggests that Saturn’s icy moon Enceladus has a subsurface ocean that sources plumes of water vapor and ice vented to space from its south pole. In situ analyses of this material by the Cassini spacecraft have shown that the ocean contains key ingredients for life (elements H, C, N, O and possibly S; simple and complex organic compounds; chemical disequilibria at water-rock interfaces; clement temperature, pressure, and pH). The Cassini discoveries make Enceladus’ interior a prime locale for life detection beyond Earth. Scant material exchange with the inner Solar System makes it likely that such life would have emerged independently of life on Earth. Thus, its discovery would illuminate life’s universal characteristics. The alternative result of an upper bound on a detectable biosphere in an otherwise habitable environment would likewise considerably advance our understanding of the prevalence of life beyond Earth. Here we outline the rationale for returning vented ocean samples, accessible from Enceladus’ surface or low altitudes, to Earth for life detection. Returning samples allows analyses using laboratory instruments that cannot be flown, with decades or more to adapt and repeat analyses. We describe an example set of measurements to estimate the amount of sample to be returned and discuss possible mission architectures and collection approaches. We then turn to the challenges of preserving sample integrity and implementing planetary protection policy. We conclude by placing such a mission in the broader context of Solar System exploration.

Enceladus↗

NASA NTRS1993

Adaptive laser link reconfiguration using constraint propagation

This paper describes Harris AI research performed on the Adaptive Link Reconfiguration (ALR) study for Rome Lab, and focuses on the application of constraint propagation to the problem of link reconfiguration for the proposed space based Strategic Defense System (SDS) Brilliant Pebbles (BP) communications system. According to the concept of operations at the time of the study, laser communications will exist between BP's and to ground entry points. Long-term links typical of RF transmission will not exist. This study addressed an initial implementation of BP's based on the Global Protection Against Limited Strikes (GPALS) SDI mission. The number of satellites and rings studied was representative of this problem. An orbital dynamics program was used to generate line-of-site data for the modeled architecture. This was input into a discrete event simulation implemented in the Harris developed COnstraint Propagation Expert System (COPES) Shell, developed initially on the Rome Lab BM/C3 study. Using a model of the network and several heuristics, the COPES shell was used to develop the Heuristic Adaptive Link Ordering (HALO) Algorithm to rank and order potential laser links according to probability of communication. A reduced set of links based on this ranking would then be used by a routing algorithm to select the next hop. This paper includes an overview of Constraint Propagation as an Artificial Intelligence technique and its embodiment in the COPES shell. It describes the design and implementation of both the simulation of the GPALS BP network and the HALO algorithm in COPES. This is described using a 59 Data Flow Diagram, State Transition Diagrams, and Structured English PDL. It describes a laser communications model and the heuristics involved in rank-ordering the potential communication links. The generation of simulation data is described along with its interface via COPES to the Harris developed View Net graphical tool for visual analysis of communications networks. Conclusions are presented, including a graphical analysis of results depicting the ordered set of links versus the set of all possible links based on the computed Bit Error Rate (BER). Finally, future research is discussed which includes enhancements to the HALO algorithm, network simulation, and the addition of an intelligent routing algorithm for BP.

Crone, M. S.↗

NASA NTRS2011

VESGEN Mapping of Bioactive Protection against Intestinal Inflammation: Application to Human Spaceflight and ISS Experiments

Challenges to successful space exploration and colonization include adverse physiological reactions to micro gravity and space radiation factors. Constant remodeling of the microvasculature is critical for tissue preservation, wound healing, and recovery after ischemia. Regulation of the vascular system in the intestine is particularly important to enable nutrient absorption while maintaining barrier function and mucosal defense against micro biota. Although tremendous progress has been made in understanding the molecular circuits regulating neovascularization, our knowledge of the adaptations of the vascular system to environmental challenges in the intestine remains incomplete. This is in part because of the lack of methods to observe and quantify the complex processes associated with vascular responses in vivo. Developed by GRC as a mature beta version, pre-release research software, VESsel GENeration Analysis (VESGEN) maps and quantifies the fractal-based complexity of vascular branching for novel insights into the cytokine, transgenic and therapeutic regulation of angiogenesis, lymphangiogenesis and microvascular remodeling. Here we demonstrate that VESGEN can be used to characterize the dynamic vascular responses to acute intestinal inflammation and mucosal recovery from in vivo confocal microscopic 3D image series. We induced transient intestinal inflammation in mice by DSS treatment and investigated whether the ability of the pro biotic yeast Saccharomyces boulardii (Sb) to protect against intestinal inflammation was due to regulation of vascular remodeling. A primary characteristic of inflammation is excessive neovascularization (angiogenesis) resulting in fragile vessels prone to bleeding. Morphological parameters for triplicate specimens revealed that Sb treatment greatly reduced the inflammatory response of vascular networks by an average of 78%. This resulted from Sb inhibition of vascular endothelial growth factor receptor signaling, a major angiogenesis signaling pathway. It needs to be determined whether pro biotic yeast represents a promising approach to GI protection in space. GRC performed only the VESGEN post-testing analysis.

Parsons-Wingerter, P. A.↗

NASA NTRS2011

Shaping NASA's Kennedy Space Center Safety for the Future

With the completion of the Space Shuttle Program, the Kennedy Space Center (KSC) safety function will be required to evolve beyond the single launch vehicle launch site focus that has held prominence for almost fifty years. This paper will discuss how that evolution is taking place. Specifically, we will discuss the future of safety as it relates to a site that will have multiple, very disparate, functions. These functions will include new business; KSC facilities not under the control of NASA; traditional payload and launch vehicle processing; and, operations conducted by NASA personnel, NASA contractors or a combination of both. A key element in this process is the adaptation of the current KSC set of safety requirements into a multi-faceted set that can address each of the functions above, while maintaining our world class safety environment. One of the biggest challenges that will be addressed is how to protect our personnel and property without dictating how other Non-NASA organizations protect their own employees and property. The past history of KSC Safety will be described and how the lessons learned from previous programs will be applied to the future. The lessons learned from this process will also be discussed as information for other locations that may undergo such a transformation.

Kirkpatrick, Paul↗

NASA NTRS2022

Microbial Life in Space

Outer space is a harsh environment harbouring multiple forms of stress like cosmic radiation, space vacuum, extreme temperature and pressure, UV radiations, and altered gravity. Earth’s atmosphere has several layers that expose microbial and terrestrial life to harsh external environments. In order to study the limits of survival of microbial life in extremes, it is imperative to study the response of micro-organisms to space-related stress. The present chapter summarizes the various balloon and flight experiments performed to investigate the presence and response of microbial life in space. Studying the microbiome in the ISS is important as pathogenic bacteria can present a major risk to astronaut health in a closed environment. Hence, studying occurrence, ecology, diversity, response, and adaptations of microbial life in space is crucial to understanding the limits of organismic survival in inhospitable conditions. Studying microbial life in space also helps predict the plausible survival and endurance of microbial travel between planets, crucial to lithopanspermia theories and planetary protection.

space↗

DOE OSTI2025

Switchable client specificity in a dual functional chaperone coordinates light-harvesting complex biogenesis

The proper assembly of light-harvesting complexes (LHCs) is critical for photosynthesis and requires the biogenesis of light-harvesting chlorophylla,b-binding proteins (LHCPs) to be coordinated with chlorophyll (Chl) biosynthesis. The mechanism underlying this coordination is not well understood. Here, we show that a conserved molecular chaperone, chloroplast signal recognition particle 43-kDa protein (cpSRP43), provides a molecular thermostat that helps maintain this coordination. cpSRP43 undergoes a conformational rearrangement between a well-folded closed state and a partially disordered open state. Closed cpSRP43 is dedicated to the biogenesis of LHCPs, whereas open cpSRP43 protects multiple Chl biosynthesis enzymes from heat-induced destabilization. Rising temperature shifts cpSRP43 to the open state, enabling it to protect heat-destabilized Chl biosynthesis enzymes. Our results reveal the molecular basis of a posttranslational mechanism for the thermoadaptation of LHC biogenesis. They also demonstrate how an adenosine triphosphate–independent chaperone uses conformational dynamics to switch its activity and client selectivity, thereby adapting to different proteostatic demands under shifting environmental conditions.

Science & Technology - Other Topics↗

NASA NTRS1999

Environmental and Archaeological Research in the Peten, Guatemala

The Peten, Northern Guatemala, was once inhabited by a population of several million Maya before their collapse in the 9th century A.D.. The seventh and eight centuries were a time of crowning glory four millions of Maya; by 930 A.D. only a few scattered houses remained, testifying to the greatest disaster in human history. What is known is that at the time of their collapse the Maya had cut down most of their trees. After centuries of regeneration the Peten now represent the largest remaining tropical forest in Central America but is experiencing rapid deforestation in the wake of an invasion of settlers. The successful adaptive techniques of the indigenous population are being abandoned in favor of the destructive techniques of monoculture and cattle raising. Remote sensing and Geographic Information System (GIS) analysis are being used to address issues in Maya archeology as well as monitor the effects of increasing deforestation in the area today. One thousand years ago the forests of the Peten were nearly destroyed by the ancient Maya who after centuries of successful adaptation finally overused their resources. Current inhabitants are threatening to do the same thing today in a shorter time period with a lesser population. Through the use of remote sensing/GIS analysis we are attempting to answer questions about the past in order to protect the resources of the future.

Sever, Thomas L.↗

NASA NTRS2000

Archaeological and Environmental Research of the Peten, Guatemala, Using Remote Sensing/GIS Research

The Peten, northern Guatemala, was once inhabited by a population of several million Maya before their collapse in the 9th century AD. Although the seventh and eight centuries were a time of crowning glory for millions of Maya; by 930 A.D. only a few scattered houses remained. What is known, is that at the time of their collapse, the Maya had cut down most of their trees. After centuries of regeneration the Peten now represent the largest remaining tropical forest in Central America but is experiencing rapid deforestation in the wake of an invasion of settlers. The successful adaptive techniques of the indigenous population are being abandoned in favor of the destructive techniques of monoculture and cattle raising. These techniques also contribute to the destruction and looting of unrecorded archeological sites. Remote sensing and GIS analysis are being used to address issues in Maya archeology as well as monitor the effects of increasing deforestation in the area today. One thousand years ago the forests of the Peten were nearly destroyed by the ancient Maya, who, after centuries of successful adaptation, finally overused their resources. Current inhabitants are threatening to do the same thing today in a shorter time period with a lesser population. Through the use of remote sensing/GIS analysis we are attempting to answer questions about the past in order to protect the resources of the future.

Sever, Thomas L.↗

NASA NTRS1980

Smokestack Monitor

Environmental Protection Agency monitors emissions from industrial smokestacks to obtain such information as how much pollutant material is being discharged into the atmosphere, how rapidly it is being discharged, and how the smoke plume disperses after leaving the stack. Raytheon's invisible laser beam, adapted from NASA's laser doppler technology, measures emission from one of the stacks. Aimed from a van's interior, the beam is projected from the roof mounted scanning pod near the rear of the vehicle. Particles in the smoke coming out of the stack reflect the beam back to light-detecting equipment in the van. The frequency of the returned beam is different from that of outgoing beam; analysis of the difference in frequencies, called "doppler shift" allows determination of the velocity.

Source record↗

NASA NTRSDate not supplied

Challenges in Securing UAM Operations

Urban air mobility (UAM) is a concept that proposes to develop short-range, point-to-point transportation systems in metropolitan areas using vertical takeoff and landing (VTOL) or short takeoff and landing (STOL) aircraft to overcome increasing surface congestion. To realize the potential of UAM, an assurance of cybersecurity is critical for public acceptance. Cybersecurity has come to the forefront highlighting the need to protect these networks and systems from cyberattacks. The growth in the development of UAM systems, and the associated data exchange and service interactions will create abundant challenges due to numerous types of cybersecurity attacks. As these threats evolve, the UAM cybersecurity capabilities must adapt to these changes as well.

Urban Air Mobility,↗

NASA NTRSDate not supplied

Challenges in Securing the Future of Air Travel

UAM↗

NASA NTRSDate not supplied

A Blockchain Case Study for Urban Air Mobility Operational Intent

The next generation of aerial passenger and cargo transportation may leverage the concept of Urban Air Mobility (UAM). UAM is a concept that proposes to develop short-range, point-to-point transportation systems in metropolitan areas using vertical takeoff and landing (VTOL) or short takeoff and landing (STOL) aircraft to overcome increasing surface congestion [1]. The UAM concept leverages a decentralized service-based architecture for airspace solutions. Within the environment, UAM operators work collaboratively to manage aerial vehicles in the urban environment. Providers of Services for UAM (PSU), UAM operators, and Supplemental Data Service Providers (SDSP) provide services to support flight operations within the UAM environment. Also, various views of UAM flight information are provided to the public and public safety entities [2]. The Federal Aviation Administration (FAA) can coordinate flight information between the FAA controlled National Airspace System (NAS) and the UAM environments through the FAA-Industry Data Exchange Protocol (FIDXP). To realize the potential of UAM, an assurance of cybersecurity is critical for public acceptance. Cybersecurity has come to the forefront highlighting the need to protect these networks and systems from cyberattacks. The growth in the development of UAM systems, and the associated data exchange and service interactions will be at risk due to numerous types of cybersecurity attacks. As these threats evolve, the UAM cybersecurity capabilities must adapt to these changes as well [3]. This research focuses on the secure data exchange and storage of this decentralized UAM environment to address these challenges. This research intends to leverage a permissioned blockchain approach to address cybersecurity threats that may impact a UAM environment. Blockchain technologies can be used for tracking transactions and verifying negotiated agreements between stakeholders in the NAS environment. For example, the record of the submitted flight plan and the approved flight plan could be verified using the Blockchain-based immutable ledger.

UAM↗

DOE OSTI2024

Identification and characterization of a skin microbiome on Caenorhabditis elegans suggests environmental microbes confer cuticle protection

ABSTRACT In the wild, C. elegans are emersed in environments teeming with a veritable menagerie of microorganisms. The C. elegans cuticular surface serves as a barrier and first point of contact with their microbial environments. In this study, we identify microbes from C. elegans natural habitats that associate with its cuticle, constituting a simple “skin microbiome.” We rear our animals on a modified CeMbio, mCeMbio, a consortium of ecologically relevant microbes. We first combine standard microbiological methods with an adapted micro skin-swabbing tool to describe the skin-resident bacteria on the C. elegans surface. Furthermore, we conduct 16S rRNA gene sequencing studies to identify relative shifts in the proportion of mCeMbio bacteria upon surface-sterilization, implying distinct skin- and gut-microbiomes. We find that some strains of bacteria, including Enterobacter sp. JUb101 , are primarily found on the nematode skin, while others like Stenotrophomonas indicatrix JUb19 and Ochrobactrum vermis MYb71 are predominantly found in the animal’s gut. Finally, we show that this skin microbiome promotes host cuticle integrity in harsh environments. Together, we identify a skin microbiome for the well-studied nematode model and propose its value in conferring host fitness advantages in naturalized contexts. IMPORTANCE The genetic model organism C. elegans has recently emerged as a tool for understanding host–microbiome interactions. Nearly all of these studies either focus on pathogenic or gut-resident microbes. Little is known about the existence of native, nonpathogenic skin microbes or their function. We demonstrate that members of a modified C. elegans model microbiome, mCeMbio, can adhere to the animal's cuticle and confer protection from noxious environments. We combine a novel micro-swab tool, the first 16S microbial sequencing data from relatively unperturbed C. elegans , and physiological assays to demonstrate microbially mediated protection of the skin. This work serves as a foundation to explore wild C. elegans skin microbiomes and use C. elegans as a model for skin research.

16S RNA↗

DOE OSTI2025

Multi-objective automatic discovery of optimized metamaterials for varying velocity impact protection

Mechanical metamaterials have demonstrated exceptional impact performance while remaining lightweight. Impact resistance has traditionally been investigated using quasi-static simulations, often with the assumption that performance will translate to high-velocity impact scenarios. However, critical crash protection parameters—such as peak stress and absorbed energy—are highly sensitive to impact velocity, leading to inconsistent performance under dynamic loading. To address this, we introduce a strain-rate-aware, active deep learning framework that enables multi-objective optimization of impact protection metrics across a wide range of impact velocities. Our framework captures the strain-rate sensitivity of architected lattices by learning to control spatial gradation in cellular metamaterials, resulting in over 200 % enhancement in impact protection relative to state-of-the-art designs such as Voronoi and re-entrant lattices. We demonstrate its practical utility by designing next-generation lattice structures for automotive bumper systems that satisfy multiple, velocity-specific safety criteria—capabilities beyond those of conventional designs. More than just a predictive tool, this framework marks the first step towards enabling adaptable impact-resistant structures across dynamic regimes.

Deep learning↗

DOE OSTI2021

Adaptive Site Management Strategies for the Hanford Central Plateau Groundwater

Adaptive site management (ASM) is a systematic and iterative management approach that can be used to expedite the remediation of large and/or complex sites. ASM is defined as a formal and systematic project or site management approach centered on rigorous site planning and a firm understanding of site conditions and uncertainties, using science and technology to routinely re-evaluate and prioritize site remedial actions and characterization activities. The goal of the approach is to create a framework of structured and continuous planning, implementation, and assessment processes that accommodates new information and changing site conditions to develop effective and efficient cleanup approaches that achieves the required outcome(s) while optimizing costs, cleanup timeframe, and performance. Central to ASM is an evolving conceptual site model (CSM). Over time, incremental reductions in uncertainty associated with the CSM will occur, while supporting continued progress toward site cleanup and closure through remedy optimization and evaluation. ASM has the potential to expedite cleanup for the Central Plateau area at Hanford through a planned and systematic approach for reducing uncertainty with targeted characterization activities, while continuing remediation activities that advance cleanup for key risk-driving contaminants. A core component of cleanup within the Central Plateau is the 200 West Pump-and-Treat (P&T) system. Even with an active P&T remedy, uncertainty exists with respect to plume distributions, total mass in the aquifer, and currently known continuing sources. Additional uncertainty is associated with multiple contaminant source locations in the vadose zone, which have the potential to create new groundwater plumes in the absence of any source control measures, although not all contaminant fluxes to groundwater will result in contaminant concentrations above cleanup levels. Collectively, these uncertainties need to be addressed in the CSM to support effective and efficient site progress toward cleanup goal(s). Other nontechnical factors that may warrant an ASM approach at the Hanford Central Plateau are associated with the formation of operable units (OUs) used to manage cleanup. With the exception of the 200-ZP-1 OU, the three remaining groundwater OUs only have interim action records of decision. Nine vadose zone source area OUs are also in the early stages of the remedial investigation and feasibility study process, with pending characterization and technology identification activities. A set of proposed site objectives for the Central Plateau are provided in this document as an initial consideration/example and basis for discussion for ASM implementation. These example site objectives were selected with the goal of maintaining protectiveness at the Columbia River through confinement of contaminant plumes within an administratively controlled area below existing surface waste sites and waste disposal facilities. Although site decision makers and regulators need to provide concurrence, these site objectives are used in this document to describe the elements of an ASM approach, including selection of interim objectives and a long-term adaptive management plan. Interim objectives are also defined to yield measurable incremental progress toward the overall site goals. This document identifies initial technical considerations for developing an ASM framework for the Central Plateau cleanup decisions. These considerations are intended to facilitate more specific decisions, such as objectives, near- and long-term actions, and performance metrics, to develop an overall approach that maintains protectiveness but recognizes the uncertainty, long timeframe, and technical challenges that need to be considered in selecting, implementing, and managing remediation at the Hanford Central Plateau.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

DOE OSTI2025

Differentially Private Map Matching (DPMM) v1.0

Human mobility trajectories provide valuable information for developing mobility applications, as they contain diverse and rich information about the users. User mobility data is valuable for various applications such as intelligent transportation systems (ITS), commercial business models, and disease-spread models. However, such spatio-temporal traces may pose a threat to user privacy. GPS trajectories in their raw form are not suitable for transportation studies, as they require matching locations with nearest road links — a process called map-matching. This software implements a differential privacy (DP)-based map-matching algorithm, called DPMM, that generates link-level location trajectories in a privacy-preserving manner to protect users' origin destinations (OD) and travel paths. OD privacy is achieved by injecting Planar Laplace noise to the user OD GPS points. Travel-path privacy is provided with randomized travel path construction using exponential DP mechanism. The injected noise level is selected adaptively, by considering the link density of the location and the functional category of the localized links. For path privacy, our mechanism samples waypoints and selects candidate paths between waypoints. DPMM provides privacy effectively with respect to link density instead of other trajectory samples in the database compared to other privacy mechanisms. Compared to the different baseline models our DP-based privacy model offers closer query responses to the raw data in terms of individual and aggregate trajectory-level statistics with an average at absolute deviation from the baseline for individual statistics on ϵ = 1.0. Beyond individual trajectory statistics, the DPMM outperforms the other benchmark DP-based mechanisms on different aggregate statistics with up to 8x improvement in utility.

Peisert, Sean [Lawrence Berkeley National Laborato↗

DOE OSTI2023

EUI Benchmarks for Net-Zero Energy Buildings in India

In our study we present EUI benchmarks for NZEBs for six building types across residential and non-residential typologies and for India's five climate zones. This approach is similar to the simulation-based benchmarks used by the B3 program in Minnesota, the Cal-Arch methodology in California, and the US Solar Decathlon approach, which combine simulations with actual building data. Of the six building types we explore one in detail with a range of operation scenarios, specifically narrowing down the EUI benchmarks for mixed-mode building operation and for variable temperature set-points as prescribed in the National Building Code of India.The contribution of this work is to provide rigorous end-use level EUI benchmarks for six building types, and to describe a method for simulation-based EUI benchmarks for mixed-mode operation with variable setpoints to highlight the difference between the standard approach used for the five building types and the On-Site Construction Worker Housing which additionally has the mixed-mode variable setpoint approach.On-Site Construction Worker Housings are typically poorly constructed temporary structures, without adequate thermal comfort, It is critical to provide adequate thermal comfort to protect people from the warming effects of climate change, and to discover super efficient and cost-effective ways to do so.The methodology used for the On-Site Construction Worker Housing (CWH) results in an 80% acceptability according to the India Model for Adaptive Comfort in the National Building Code of India. EUIs of all six buildings are 60% lower than the minimum compliance with India's Energy Conservation Building Codes, providing benchmarks for efficiency levels. The end-use level EUI benchmarks are now provided to over 1800 Solar Decathlon India participants so that they can compare the performance of their NZEB designs.In particular, the CWH results provide an insight into the importance of the mixed-mode operation with variable temperature set-points. The results from the simulation study show that for an NZEB target, the EUI with standard thermal comfort model and without mixed operation is 58.26 kWh/m2*year, while that with the variable set-points of the adaptive model with mixed mode operation is 24.23 kWh/m2*year. This is a 58% reduction in EUI. Given that many building types including residential, and non-residential operate in mixed mode, it is important to take this work further to develop mixed-mode operation NZEB benchmarks so that the carbon intensity of these buildings could be lower than the standard thermal comfort model approach.

benchmarking↗

NASA NTRS1980

Test fittings for dimensionally critical tubes

Method using lightweight fitting protects tubes and tube stubs during testing and through to final welding. Fitting does not interfere with final welding or brazing like temporary test fittings, and is not heavy like machined-on integral fittings with face-seal 0-rings. Fitting approach is adaptable to many types of components, including valves, transducers, and filters.

Hagler, R.↗