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At least 343 records · Page 19

First Plant Cell Atlas symposium report

The Plant Cell Atlas (PCA) community hosted a virtual symposium on December 9 and 10, 2021 on single cell and spatial omics technologies. The conference gathered almost 500 academic, industry, and government leaders to identify the needs and directions of the PCA community and to explore how establishing a data synthesis center would address these needs and accelerate progress. This report details the presentations and discussions focused on the possibility of a data synthesis center for a PCA and the expected impacts of such a center on advancing science and technology globally. Community discussions focused on topics such as data analysis tools and annotation standards; computational expertise and cyber-infrastructure; modes of community organization and engagement; methods for ensuring a broad reach in the PCA community; recruitment, training, and nurturing of new talent; and the overall impact of the PCA initiative. These targeted discussions facilitated dialogue among the participants to gauge whether PCA might be a vehicle for formulating a data synthesis center. The conversations also explored how online tools can be leveraged to help broaden the reach of the PCA (i.e., online contests, virtual networking, and social media stakeholder engagement) and decrease costs of conducting research (e.g., virtual REU opportunities). Major recommendations for the future of the PCA included establishing standards, creating dashboards for easy and intuitive access to data, and engaging with a broad community of stakeholders. The discussions also identified the following as being essential to the PCA's success: identifying homologous cell-type markers and their biocuration, publishing datasets and computational pipelines, utilizing online tools for communication (such as Slack), and user-friendly data visualization and data sharing. In conclusion, the development of a data synthesis center will help the PCA community achieve these goals by providing a centralized repository for existing and new data, a platform for sharing tools, and new analytical approaches through collaborative, multidisciplinary efforts. A data synthesis center will help the PCA reach milestones, such as community-supported data evaluation metrics, accelerating plant research necessary for human and environmental health.

59 BASIC BIOLOGICAL SCIENCES↗

Toward a Resilient Cybersecure Hydropower Fleet: Cybersecurity Landscape and Roadmap 2021

With this roadmap, Pacific Northwest National Laboratory (PNNL) hopes to assist the U.S. Department of Energy’s (DOE’s) Water Power Technologies Office (WPTO) in improving the cybersecurity of hydropower plants across the nation. This effort draws upon collected data from the dams sector, from industrial control system cybersecurity threat reports, from similar work focused on neighboring sectors, and from frank discussions with owners, operators, and vendors. While remaining tightly focused on the needs of hydropower projects, during this landscape study and development of the resulting roadmap, the research team sought to remain informed by the larger energy sector’s vision and direction so that the topics and milestones may fit within a larger vision common to the whole.

13 HYDRO ENERGY↗

The NREL Sensor Laboratory Detection of Hydrogen Emissions

The development of a functional hydrogen detection system is a multifaceted process that integrates hardware, deployments strategies, and analytics which can be supported by the NREL Sensor Laboratory: 1. Support of the design, validation and optimization of sensing prototypes; 2. Guide optimized sensing element development, including control electronics; 3. Laboratory testing to validate/optimize metrological performance (measurement range, detection limit, etc.); 4. Provide test sites for field deployments representative of real-world scenarios with controlled hydrogen releases; 5. Develop sensor placement and operation guidance; 6. Provide guidance on electronics to accommodate facility integration; 7. Electrical safety designs to allow for operation within restricted zones; 8. Integration into facility monitoring and control systems; 9. Guide incorporation of cyber security elements to protect facilities from malicious attacks; 10. Modeling and application of advanced analytics to detect and quantify emissions; 11. Higher Order dispersion models to guide sensor placement for reliable detection; 12. Advanced analytics for improved metrological performances, and to inform inverse modeling; 13. Market support and commercialization (national and international markets); 14. Commercial deployments in H2@SCALE markets (e.g., HUBs and other large-scale hydrogen markets); and 15. Leverage off international collaborations/partnerships (e.g., NREL is on the advisory board for the European initiative "pre-Normative Research on Hydrogen Releases Assessment"-NHyRA).

08 HYDROGEN↗

Materials and Fuels Complex Five-Year Mission Strategy (FY21- FY25)

The Idaho National Laboratory (INL), through its designated mission of advancing innovative nuclear energy solutions, is actively engaged in the research, development, demonstration and deployment of advanced nuclear technology, as well as in fostering private-public partnership for technology development. Key to the success of INL’s mission is the Materials and Fuels Complex (MFC), the only complex in the U.S. that hosts a world-class assemblage of facilities, capabilities and instruments for handling, testing, and characterizing radioactive materials. Driven by its mission/vision of “Engineering and Experiments that Drive the World’s Nuclear Energy Future,” MFC is at the center of INL’s – and indeed the Department of Energy’s – advanced nuclear technology development initiatives, providing essential capabilities such as engineering-scale high-assay low-enriched uranium (HALEU) fuel production, reactor demonstration facilities, post-irradiation examination, and transient irradiation testing. Furthermore, MFC provides an ideal environment for test beds that are utilized for research, development and demonstration (RD&D) activities on used fuel treatment, nuclear non-proliferation, forensics, and nuclear power sources used for space exploration missions conducted by the National Aeronautics and Space Administration (NASA).

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Electrification FY2020 Annual Progress Report

The Electric Drive Technologies (EDT) program’s mission is to conduct early-stage research and development on transportation electrification technologies that accelerate the development of cost-effective and compact electric traction drive systems that meet or exceed performance and reliability requirements of internal combustion engine (ICE)-based vehicles, thereby enabling electrification across all light-duty vehicle types.

33 ADVANCED PROPULSION SYSTEMS↗

Potential Academic Research Topics of National Security Relevance

Since even before its establishment as an independent national security laboratory in 1949, Sandia has been devoted to an overarching mission of developing advanced technologies for global peace. These technologies have taken a variety of forms, and they exist in and must address an ever-changing global security environment. An understanding of that global security environment and its possible or likely evolution is therefore critical to ensuring that Sandia can maintain its focus on strategic technology investments that will benefit the nation in the next 20- 30 years. Sandia sustains multiple Systems Analysis organizations whose responsibility includes maintaining an understanding of the global security environment as it applies across multiple mission domains. The topics below include two from Sandia's emerging threats and biodefense mission, three with relevance to Sandia's cyber defense mission, and four of particular but not exclusive relevance to Sandia's nuclear deterrence mission. All are intended to spur independent academic thought that could assist Sandia as well as the broader national security community in anticipating and adapting to a continually changing world. Sandia anticipates periodic interactions between Sandia Systems Analysis staff and SciPol Scholars Program faculty and students who choose to expand upon these topics in order to provide opportunities for feedback and communication throughout 2020-2021.

54 ENVIRONMENTAL SCIENCES↗

Vision 2040: A Roadmap for Integrated, Multiscale Modeling and Simulation of Materials and Systems

Over the last few decades, advances in high-performance computing, new materials characterization methods, and, more recently, an emphasis on integrated computational materials engineering (ICME) and additive manufacturing have been a catalyst for multiscale modeling and simulation-based design of materials and structures in the aerospace industry. While these advances have driven significant progress in the development of aerospace components and systems, that progress has been limited by persistent technology and infrastructure challenges that must be overcome to realize the full potential of integrated materials and systems design and simulation modeling throughout the supply chain. As a result, NASA's Transformational Tools and Technology (TTT) Project sponsored a study (performed by a diverse team led by Pratt & Whitney) to define the potential 25-year future state required for integrated multiscale modeling of materials and systems (e.g., load-bearing structures) to accelerate the pace and reduce the expense of innovation in future aerospace and aeronautical systems. This report describes the findings of this 2040 Vision study (e.g., the 2040 vision state; the required interdependent core technical work areas, Key Element (KE); identified gaps and actions to close those gaps; and major recommendations) which constitutes a community consensus document as it is a result of over 450 professionals input obtain via: 1) four society workshops (AIAA, NAFEMS, and two TMS), 2) community-wide survey, and 3) the establishment of 9 expert panels (one per KE) consisting on average of 10 non-team members from academia, government and industry to review, update content, and prioritize gaps and actions. The study envisions the development of a cyber-physical-social ecosystem comprised of experimentally verified and validated computational models, tools, and techniques, along with the associated digital tapestry, that impacts the entire supply chain to enable cost-effective, rapid, and revolutionary design of fit-for-purpose materials, components, and systems. Although the vision focused on aeronautics and space applications, it is believed that other engineering communities (e.g., automotive, biomedical, etc.) can benefit as well from the proposed framework with only minor modifications. Finally, it is TTT's hope and desire that this vision provides the strategic guidance to both public and private research and development decision makers to make the proposed 2040 vision state a reality and thereby provide a significant advancement in the United States global competitiveness.

multi-scale modeling↗

Pillars of Innovation Across Southeast Idaho & the Interstate-15 Corridor

Since 1949, Idaho National Laboratory (INL) has been home to developing civilian and defense nuclear reactor technologies and managing spent nuclear fuel. Today, INL is the nation’s nuclear energy research laboratory, sustaining the safe and efficient operation of existing reactors, powering science in space, and breaking ground on the future fleet of advanced nuclear reactors. INL is only one of many rising technology resources in the region, however. Along the Interstate 15 (I-15) corridor, technology and cybersecurity industries and intellectual assets are rapidly expanding. Creating an innovation hub in this region would unite capabilities to solve current and future challenges in nuclear reactor sustainment and expanded deployment, integrated fuel cycle solutions, integrated energy systems, advanced materials and manufacturing for extreme environments, and secure and resilient cyber-physical systems.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

Land-Based Wind Reference Architecture

This report describes a summary and the final deliverables for the Wind Reference Architecture project funded by the Department of Energy's (DOE) Wind Energy Technology Office (WETO). The project objective was to further refine the reference architecture of the existing wind power plant reference architecture developed by Idaho National Laboratory (INL) and Sandia National Laboratories (SNL) by expanding the wind turbine generator (WTG) into a separate individual wind turbine reference architecture. Additional details regarding the wind turbine system and how it integrates with a wind power plant were researched and reflected in the reference architecture. This addition is important because it allows researchers to understand the components and devices in a wind turbine, how they function and how a wind turbine integrates into a wind power plant to be able to perform cybersecurity evaluations on the system. The communication and control systems were the focus while developing this reference architecture to understand the cybersecurity posture of a wind turbine and power plant. The information technology (IT) and operational technology (OT) systems perspective are integral in helping improve the cybersecurity posture by creating a starting point to study how wind energy can be safely designed and deployed in our power grid from an integrated systems standpoint. A holistic wind power plant and turbine reference architecture and simulation was developed and made open-sourced for further research efforts.

17 WIND ENERGY↗

The Importance of Earth Observations and Data Collaboration within Environmental Intelligence Supporting Arctic Research

Within the IARPC Collaboration Team activities of 2016, Arctic in-situ and remote earth observations advanced topics such as :1) exploring the role for new and innovative autonomous observing technologies in the Arctic; 2) advancing catalytic national and international community based observing efforts in support of the National Strategy for the Arctic Region; and 3) enhancing the use of discovery tools for observing system collaboration such as the U.S. National Oceanic and Atmospheric Administration (NOAA) Arctic Environmental Response Management Application (ERMA) and the U.S. National Aeronautics and Space Administration (NASA) Arctic Collaborative Environment (ACE) project geo reference visualization decision support and exploitation internet based tools. Critical to the success of these earth observations for both in-situ and remote systems is the emerging of new and innovative data collection technologies and comprehensive modeling as well as enhanced communications and cyber infrastructure capabilities which effectively assimilate and dissemination many environmental intelligence products in a timely manner. The Arctic Collaborative Environment (ACE) project is well positioned to greatly enhance user capabilities for accessing, organizing, visualizing, sharing and producing collaborative knowledge for the Arctic.

Casas, Joseph↗

Astronauts and IoT: Toward True Human-Autonomy Teaming

Advances in the area of Internet of Things (IoT) or Cyber-Physical Systems will have a significant impact on many areas of human activity and commercial/technological development. One application of importance to NASA is the need to make crews on deep space missions more independent from earth in both their routine activities and handling of unexpected events. IoT will allow increasingly intelligent systems to be aware of what humans are doing, what tools/resources they are using, and what help they might need in terms of procedure execution in tasks such as assembly, maintenance, repair, and perhaps even in more complex activities like medical interventions. This talk focuses on the convergence of research and technologies that will be needed to effect such intelligent systems based on IoT.

Internet of Things (IoT)↗

MFANS 2024 - Formally Proving Characteristics of Cyber-Physical Systems

Cyber-physical systems (CPS) are engineered systems that rely on the smooth integration of computational algorithms and physical elements. This integration presents new challenges for verifying that systems will behave as expected. The goal of this presentation is to present current challenges and potential solutions for the formal verification of cyber-physical systems. For cyber systems, formal methods refer to systematically rigorous mathematical techniques employed in the specification, development, analysis, and verification of both software and hardware systems. Recent advancements in computer science have yielded sophisticated tools specifically designed to address challenges associated with formal methods in complex systems. These tools leverage various foundational concepts such as logic, formal languages, program semantics, type systems, type theory, and automata theory. A notable achievement in the application of formal methods is the seL4 microkernel, claimed to be the first general-purpose operating-system kernel to be verified. Its proof implies the absence of bugs and guarantees that the kernel meets specifications. For physical systems, dynamic and control theory has a history of using rigorous analytic techniques to prove functional correctness. Lyapunov, optimal, classical, modern, and robust control theories all provide rigorous mathematical methods both to analyze system performance and to design controller that can be guaranteed to meet certain objectives. Recent computational techniques like level set theory and reachability analysis provide assertions that a system's state will avoid unsafe regions. Even though success has been independently achieved for cyber systems and physical systems, the integration of such systems creates new challenges. In particular, there is an obvious discrepancy between finite-state machines and infinite-state systems, resulting in different approaches for modeling and analyzing these system. While it is possible to simulate hybrid systems, this provides only a demonstration of a performance and not proof. For hybrid systems, current formal methods and system analysis approaches typically require a workarounds to work on hybrid systems like CPS. This paper will outline the state of the art and limits of current practice for formally verifying CPS and will identify possible research directions that require attention.

97 MATHEMATICS AND COMPUTING↗

A color graphics environment in support of supercomputer systems

An initial step in the integration of an upgrade of a VPS-32 supercomputer to 16 million 64-bit words, to be closely followed by a further upgrade to 32 million words, was to develop a graphics language commonality with other computers at the Langley Center. The power of the upgraded supercomputer is to users at individual workstations, who will aid in defining the direction for future expansions in both graphics software and workstation requirements for the supercomputers. The LAN used is an ETHERNET configuration featuring both CYBER mainframe and PDP 11/34 image generator computers. The system includes a film recorder for image production in slide, CRT, 16 mm film, 35 mm film or polaroid film images. The workstations have screen resolutions of 1024 x 1024 with each pixel being one of 256 colors selected from a palette of 16 million colors. Each screen can have up to 8 windows open at a time, and is driven by a MC68000 microprocessor drawing on 4.5 Mb RAM, a 40 Mb hard disk and two floppy drives. Input is from a keyboard, digitizer pad, joystick or light pen. The system now allows researchers to view computed results in video time before printing out selected data.

Smith-Taylor, R.↗

Envisioning the Future Renewable and Resilient Energy Grids—A Power Grid Revolution Enabled by Renewables, Energy Storage, and Energy Electronics

Today’s power grids are facing tremendous challenges because of the ever-increasing power demand, system complexity, infrastructure cost, knowledge base, and policy and regulatory issues to achieve supply–demand power balance and resiliency with respect to more frequent extreme weather events and cyberattacks. It is particularly challenging when the transition toward 100% intermittent renewable energy sources is considered. Many countries are calling for building up more transmission and distribution lines to increase power delivery capacities. This article is an attempt to answer two urgent questions: Is more transmission and distribution infrastructure really needed to meet the increasing power demand? What kind of future grid infrastructure should we envision and build? This article attempts to answer these questions and proposes the concept of community-centric asynchronous renewable and resilient energy grids. By clearly differentiating the concepts of grid resilience and reliability, the importance of building resilient power electronics’ devices and robust system-level control algorithms to achieve 100% renewable energy integrated resilient grids is presented. To identify the shortcomings and propose advancements, power electronics’ technologies are categorized using the proposed concepts of natural source frequencies (NSf), energy storage, direct energy conversion/control and fault protection (DeCaFp), and high-efficiency energy consumption and buffering (heECaB) technology. The ability of networked microgrids to greatly reduce power outages and power system restoration time is demonstrated by leveraging robust decentralized and centralized control algorithms, identified through a comprehensive literature review. Future research areas are proposed to further enhance grid stability, controllability, cybersecurity, and protection against faults in the presence of 100% renewable sources by leveraging the advanced capabilities of NSf, DeCaFp, and heECaB devices and system-level control algorithms.

14 SOLAR ENERGY↗

Developing a Supply Chain Security Program

Amid growing concerns over foreign manufacturing for components and devices deployed in critical energy infrastructure, this research from the national labs will highlight best practices for developing and maintaining a supply chain security program. Tools for asset inventory, tips for developing and maintaining software- and hardware-bills-of-materials (SBOMs and HBOMs), recommended contractual language for vendor agreements, and identification of responsibilities will be shared. We discuss the one-time requirements to enable a successful supply chain security program and the best ways to operationalize this program for maximum impact, including development of robust practices for vulnerability tracking, patch management, and workarounds, with understanding of the reliability and uptime requirements for utilities. The recommendations shared are based on a cyber-informed engineering approach to identification of high-consequence impacts and the engineering controls related to supply chain management that can best mitigate these impacts. This approach allows for prioritization of resources. Additionally, we highlight relative up-front and ongoing costs associated with recommended controls. Viewers will leave with an understanding what a supply chain security program is, and what steps, prioritized for resource-constrained organizations, can build a robust program.

14 SOLAR ENERGY↗

Theoretical studies of Resonance Enhanced Stimulated Raman Scattering (RESRS) of frequency doubled Alexandrite laser wavelength in cesium vapor

The third phase of research will focus on the propagation and energy extraction of the pump and SERS beams in a variety of configurations including oscillator structures. In order to address these questions a numerical code capable of allowing for saturation and full transverse beam evolution is required. The method proposed is based on a discretized propagation energy extraction model which uses a Kirchoff integral propagator coupled to the three level Raman model already developed. The model will have the resolution required by diffraction limits and will use the previous density matrix results in the adiabatic following limit. Owing to its large computational requirements, such a code must be implemented on a vector array processor. One code on the Cyber is being tested by using previously understood two-level laser models as guidelines for interpreting the results. Two tests were implemented: the evolution of modes in a passive resonator and the evolution of a stable state of the adiabatically eliminated laser equations. These results show mode shapes and diffraction losses for the first case and relaxation oscillations for the second one. Finally, in order to clarify the computing methodology used to exploit the speed of the Cyber's computational speed, the time it takes to perform both of the computations previously mentioned to run on the Cyber and VAX 730 must be measured. Also included is a short description of the current laser model (CAVITY.FOR) and a flow chart of the test computations.

Lawandy, Nabil M.↗

The Digital Assurance for High Consequence Systems (DAHCS) Mission Campaign Whitepaper

The DAHCS (pronounced “Dax”) MC is a 7-year, $\$$45 million research portfolio within Sandia’s Laboratory Directed Research and Development program. The DAHCS MC arose in response to a great need: to ensure that the use of digital technologies does not weaken our nation’s high consequence systems. Digital technologies offer many benefits in speed, cost, and flexibility, and we seek to reap those benefits without introducing new system failures. However, digital technologies cannot be evaluated the same way as analog technologies. Initiatives across the nation highlight the capability gap that prevents efficient, effective digital assurance. The Challenge Today’s digital assurance tools, techniques, and methods are inadequate to confidently characterize, assess, and manage digital risk; they are ad hoc, slow, costly, and rarely scalable to increasingly complex digital technologies. The rapidly evolving cyber threat landscape exacerbates this problem because digital assurance now must secure against digital risks now and in the future, including those introduced by rapidly evolving technologies, adversaries, and systems.

97 MATHEMATICS AND COMPUTING↗

Comparisons of some large scientific computers

In 1975, the National Aeronautics and Space Administration (NASA) began studies to assess the technical and economic feasibility of developing a computer having sustained computational speed of one billion floating point operations per second and a working memory of at least 240 million words. Such a powerful computer would allow computational aerodynamics to play a major role in aeronautical design and advanced fluid dynamics research. Based on favorable results from these studies, NASA proceeded with developmental plans. The computer was named the Numerical Aerodynamic Simulator (NAS). To help insure that the estimated cost, schedule, and technical scope were realistic, a brief study was made of past large scientific computers. Large discrepancies between inception and operation in scope, cost, or schedule were studied so that they could be minimized with NASA's proposed new compter. The main computers studied were the ILLIAC IV, STAR 100, Parallel Element Processor Ensemble (PEPE), and Shuttle Mission Simulator (SMS) computer. Comparison data on memory and speed were also obtained on the IBM 650, 704, 7090, 360-50, 360-67, 360-91, and 370-195; the CDC 6400, 6600, 7600, CYBER 203, and CYBER 205; CRAY 1; and the Advanced Scientific Computer (ASC). A few lessons learned conclude the report.

Credeur, K. R.↗