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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 343 records · Page 19
All sourcesNASA NTRSDOE OSTI
DOE OSTI2020

Advancing How We Learn from Biodesign to Mitigate Risks with Next-Generation Genome Engineering

In the last decade, the unprecedented simplicity and flexibility of the CRISPR-Cas system has made it the dominant transformative tool in gene and genome editing. However, this democratized technology is both a boon and a bane, for which we have yet to understand the full potential to investigate and rewrite genomes (also named “genome biodesign”). Rapid CRISPR advances in a range of applications in basic research, agriculture, and clinical applications pose new risks and raise several biosecurity concerns. In such a fast-moving field of research, we emphasize the importance of properly communicating the quality and accuracy of results and recommend new reporting requirements for results derived from next-generation genome engineering.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2022

Reflection on the Challenges, Accomplishments, and New Frontiers of Gene Drives

Ongoing pest and disease outbreaks pose a serious threat to human, crop, and animal lives, emphasizing the need for constant genetic discoveries that could serve as mitigation strategies. Gene drives are genetic engineering approaches discovered decades ago that may allow quick, super-Mendelian dissemination of genetic modifications in wild populations, offering hopes for medicine, agriculture, and ecology in combating diseases. Following its first discovery, several naturally occurring selfish genetic elements were identified and several gene drive mechanisms that could attain relatively high threshold population replacement have been proposed. This review provides a comprehensive overview of the recent advances in gene drive research with a particular emphasis on CRISPR-Cas gene drives, the technology that has revolutionized the process of genome engineering. Herein, we discuss the benefits and caveats of this technology and place it within the context of natural gene drives discovered to date and various synthetic drives engineered. Later, we elaborate on the strategies for designing synthetic drive systems to address resistance issues and prevent them from altering the entire wild populations. Lastly, we highlight the major applications of synthetic CRISPR-based gene drives in different living organisms, including plants, animals, and microorganisms.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2020

NS 1987A in SN 1987A

The possible detection of a compact object in the remnant of SN 1987A presents an unprecedented opportunity to follow its early evolution. The suspected detection stems from an excess of infrared emission from a dust blob near the compact object’s predicted position. The infrared excess could be due to the decay of isotopes like 44 Ti, accretion luminosity from a neutron star or black hole, magnetospheric emission or a wind originating from the spin down of a pulsar, or to thermal emission from an embedded, cooling neutron star. In this work it is shown that the last possibility is the most plausible as the other explanations are disfavored by other observations and/or require fine-tuning of parameters. Not only are there indications that the dust blob overlaps the predicted location of a kicked compact remnant, but its excess luminosity also matches the expected thermal power of a 30 yr old neutron star. Furthermore, models of cooling neutron stars within the minimal cooling paradigm readily fit both NS 1987A and Cas A, the next-youngest known neutron star. If correct, a long heat transport timescale in the crust and a large effective stellar temperature are favored, implying relatively limited crustal n- 1 S 0 superfluidity and an envelope with a thick layer of light elements, respectively. If the locations do not overlap, then pulsar spin down or accretion might be more likely, but the pulsar’s period and magnetic field or the accretion rate must be rather finely tuned. In this case, NS 1987A may have enhanced cooling and/or a heavy-element envelope.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2024

Nucleosynthetic Analysis of Three-dimensional Core-collapse Supernova Simulations

Abstract We study in detail the ejecta conditions and theoretical nucleosynthetic results for 18 three-dimensional core-collapse supernova (CCSN) simulations done by F ornax . Most of the simulations are carried out to at least 3 s after bounce, which allows us to follow their longer-term behaviors. We find that multidimensional effects introduce many complexities into the ejecta conditions. We see a stochastic electron fraction evolution, complex peak temperature distributions and histories, and long-tail distributions of the time spent within nucleosynthetic temperature ranges. These all lead to substantial variation in CCSN nucleosynthetic yields and differences from 1D results. We discuss the production of lighter α -nuclei, radioactive isotopes, heavier elements, and a few isotopes of special interest. Comparing pre-CCSN and CCSN contributions, we find that a significant fraction of elements between roughly Si and Ge are generally produced in CCSNe. We find that 44 Ti exhibits an extended production timescale as compared to 56 Ni, which may explain its different distribution and higher than previously predicted abundances in supernova remnants such as Cas A and SN1987A. We also discuss the morphology of the ejected elements. This study highlights the high-level diversity of ejecta conditions and nucleosynthetic results in 3D CCSN simulations and emphasizes the need for additional long-term (∼10 s) 3D simulations to properly address such complexities.

Astronomy & Astrophysics↗
DOE OSTI2026

Simulation to a Newborn Supernova Remnant from a Low-mass Iron Core Star

Supernova remnant observations show a high degree of asymmetry, mixing, and inhomogeneity. These asymmetries are seeded during the early seconds of the explosion and are further enhanced and modified as the shock and ejecta move through the stellar progenitor and into the circumstellar medium. We present simulations of a 9.6 M⊙ zero-metallicity progenitor initialized after shock revival and evolved for several years when the ejecta is in the circumstellar medium. A suite of 1D and 2D simulations examines the effects of neutron-star wind and radioactive decay heating. In 1D, decay heating forms a low-density bubble that suppresses the reverse shock. While in 2D, the heating is localized to metal-rich pockets, inflating them and compressing the surrounding material into dense shells. In 3D, the neutron-star wind and decay heating modify the plume morphology, producing more large-scale structures. The extended plume morphology leads to an asymmetrical shock breakout. After breakout, the leading plumes cannot keep up with the shock front, resulting in deceleration and fragmentation by the reverse shock while retaining the large-scale asymmetry. The projected ejecta morphology and velocities are strongly viewing angle dependent. The relatively uniform metal-rich distribution does not resemble the strongly inhomogeneous ejecta structure of Cas A. The 160-isotope decay network shows that 24.4% of the radioactive heating comes from decay chains other than the canonical 56Ni chain. The low explosion energy, low 56Ni yield, and Ni/Fe ratio greater than unity suggest an observational signature similar to an electron capture supernova.

Neopane, Sudarshan [University of Tennessee (UT)]↗
DOE OSTI2023

Evaluation of four ground-based retrievals of cloud droplet number concentration in marine stratocumulus with aircraft in situ measurements

Abstract. Cloud droplet number concentration (Nd) is crucial for understanding aerosol–cloud interactions (ACI) and associated radiative effects. We present evaluations of four ground-based Nd retrievals based on comprehensive datasets from the Atmospheric Radiation Measurement (ARM) Aerosol and Cloud Experiments in the Eastern North Atlantic (ACE-ENA) field campaign. The Nd retrieval methods use ARM ENA observatory ground-based remote sensing observations from a micropulse lidar, Raman lidar, cloud radar, and the ARM NDROP (Droplet Number Concentration) value-added product (VAP), all of which also retrieve cloud effective radius (re). The retrievals are compared against aircraft measurements from the fast cloud droplet probe (FCDP) and the cloud and aerosol spectrometer (CAS) obtained from low-level marine boundary layer clouds on 12 flight days during summer and winter seasons. Additionally, the in situ measurements are used to validate the assumptions and characterizations used in the retrieval algorithms. Statistical comparisons of the probability distribution function (PDF) of the Nd and cloud re retrievals with aircraft measurements demonstrate that these retrievals align well with in situ measurements for overcast clouds, but they may substantially differ for broken clouds or clouds with low liquid water path (LWP). The retrievals are applied to 4 years of ground-based remote sensing measurements of overcast marine boundary layer clouds at the ARM ENA observatory to find that Nd (re) values exhibit seasonal variations, with higher (lower) values during the summer season and lower (higher) values during the winter season. The ensemble of various retrievals using different measurements and retrieval algorithms such as those in this paper can help to quantify Nd retrieval uncertainties and identify reliable Nd retrieval scenarios. Of the retrieval methods, we recommend using the micropulse lidar-based method. This method has good agreement with in situ measurements, less sensitivity to issues arising from precipitation and low cloud LWP and/or optical depth, and broad applicability by functioning for both daytime and nighttime conditions.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2023

Evaluation of Four Ground-based Retrievals of Cloud Droplet Number Concentration in Marine Stratocumulus with Aircraft In Situ Measurements

Cloud droplet number concentration (N d ) is crucial for understanding aerosol-cloud interactions (ACI) and associated radiative effects. We present evaluations of four ground-based N d retrievals based on comprehensive datasets from the Atmospheric Radiation Measurements (ARM) Aerosol and Cloud Experiments in the Eastern North Atlantic (ACE-ENA) field campaign. The N d retrieval methods use ARM ENA observatory ground-based remote sensing observations from a Micropulse lidar, Raman lidar, cloud radar, and the ARM NDROP Value-added Product (VAP), all of which also retrieve cloud effective radius (r e ). The retrievals are compared against aircraft measurements from the Fast-Cloud Droplet Probe (FCDP) and the Cloud and Aerosol Spectrometer (CAS) obtained from low-level marine boundary layer clouds on 12 flight days during summer and winter seasons. Additionally, the in situ measurements are used to validate the assumptions and characterizations used in the retrieval algorithms. Statistical comparisons of the probability distribution function (PDF) of the N d and cloud r e retrievals with aircraft measurements demonstrate that these retrievals align well with in situ measurements for overcast clouds, but they may substantially differ for broken clouds or clouds with low liquid water path (LWP). The retrievals are applied to four years of ground-based remote sensing measurements of overcast marine boundary layer clouds at the ARM ENA observatory to find that N d (r e ) values exhibit seasonal variations, with higher (lower) values during the summer season and lower (higher) values during the winter season. The ensemble of various retrievals using different measurements and retrieval algorithms such as those in this paper can help to quantify N d retrieval uncertainties and identify reliable N d retrieval scenarios. Of the retrieval methods, we recommend using the using the Micropulse lidar-based method given its good agreement with in situ measurements, it has less sensitivity to issues arising from precipitation and low cloud LWP/optical depth, and it has broad applicability by functioning for both day and nighttime conditions.

54 ENVIRONMENTAL SCIENCES↗
NASA NTRS1972

Balmer continuous emission and polarization in Be stars

Observations by OAO-2 of two Be stars, gamma Cassiopeiae and 60 Cygni, are analyzed to show that unpolarized radiation produced by Balmer continuous emission in the extended atmospheres of Be stars is probably a significant factor in explaining the polarization observed shortwards of the Balmer discontinuity. The ratio of the energy flux of Be stars to normal B stars with the same amount of reddening varies from about 1.4 at 3600 A to 1.05 at 2500 A. This is interpreted as due to Balmer continuous emission in the Be stars. For gamma Cas the polarizations at 3300 and 3600 A are respectively 0.6 and 0.7 of the values one expects from interstellar polarization.

Coyne, G. V.↗
NASA NTRS1972

Infrared objects in H II regions.

The discovery of 2-micron emission sources in NGC 2264, IC 2087, and M1-82, and of prominent infrared emission in Lk H-alpha 198 and V376 Cas is reported. Of the 25 objects found by scanning around the H II regions, less than half would appear to be late-type stars.

Allen, D. A.↗
NASA NTRS1972

Observations of the stellar Mg II resonance doublet at 2795 and 2802 A.

Spectrophotometry of the Mg II resonance doublet at 2795.5 and 2802.7 A has been performed for five stars with a balloon-borne telescope and spectrometer. Spectral resolution attained was between 0.25 and 0.5 A. A description of the payload and flight operations is given. In beta Lyr the Mg II doublet displayed P Cygni characteristics, while in gamma Lyr the doublet was observed only in absorption. The star beta Cas shows broad overlapping Mg II absorption lines with possible weak emission at the line bottom. In alpha CMi, both components of the doublet are seen in emission at the bottom of the broad absorption feature. The Mg II doublet in alpha Ori is entirely in emission, with each component showing distinct self-reversal.

Kondo, Y.↗
NASA NTRS1972

Low energy X-ray survey from the Crab Nebula to Cygnus.

Observations of cosmic X-rays in the energy band 0.2-3.0 keV were made from an experiment on board an Aerobee 170 rocket launched from White Sands, N.M. on Dec. 19, 1970. A survey along the galactic plane between the Crab Nebula and Cygnus provided data on the interstellar absorption and X-ray flux for the Crab Nebula, NP 0532, Cas A, and Cyg X-2; upper limits were obtained for the flux from a number of supernova remnants. The 1/4 keV X-ray background was measured over a limited range of galactic latitude and longitude.

Garmire, G.↗
NASA NTRS1972

A flux-density scale for microwave frequencies.

Accurate flux-density measurements of the thermal radio source DR 21 have been made at centimeter wavelengths relative to the KPW absolute flux-density scale based on Cas A and at millimeter wavelengths relative to absolute brightness-temperature measurements of Jupiter and Saturn. The form of the absolute spectrum of DR 21 thus defined is given and used to relate two formerly independent flux-density scales. With an accuracy of about 3 percent, this spectrum of DR 21 defines a flux-density scale that can be used to calibrate antennas having beamwidths between 1 and 6 minutes of arc at microwave frequencies above 7 GHz where other methods of absolute calibration are much less accurate.

Dent, W. A.↗
NASA NTRS1973

X-ray spectrum of Cassiopeia A - Evidence for iron line emission.

A sensitive measurement by rocket-borne detectors of the X-ray flux from Cas A has revealed a steep continuum and a broad spectral feature in the region where line radiation from iron nuclei would be expected. The flux in this feature is 0.0122 plus or minus 0.0017 photons per sq cm per sec. The presence of broad iron lines is consistent with a model in which about 13 MeV-per-nucleon iron nuclei charge exchange with surrounding interstellar oxygen and other heavy atoms. The model suggests that a substantial fraction of the energy from the outburst has gone into low-energy cosmic rays which produce the observed H II region surrounding the remnant.

Serlemitsos, P. J.↗
NASA NTRS1975

Time variations of UV emission features of Be stars

The UV spectra of three Be stars (gamma Cas, sigma Tau, eta Cen) were studied. Of the six Be stars observed in the first four lines of the Balmer series, three stars showed at least one of the Balmer lines to be variable in the equivalent width amounting to a few percent with time scales of 3 to 30 minutes. Photoelectric spectrum scans of five southern Wolf-Rayet stars showed night-to-night variations. A simple model is proposed to account for the behavior of these emission lines. Scans of gamma square Vel showed rapid variations of emission strengths of He II 4686 and C III - IV 4650. These variations have time scales of 1 minute and longer. Night-to-night variations were also found. Scans of four Be stars in H alpha showed a definite variation of 3 to 4 percent, with time scales of 1 minute and longer in sigma Tau. In 48 Per and kappa Dra the variations are not as well established. No variation of any significance was found for nu Gem.

Bahng, J. D. R.↗
NASA NTRS1974

The X-ray spectra of the Vela and Puppis supernova remnants and the shock-wave model of supernova remnants

The structure and spectrum of the Vela and Puppis supernova remnants (SNRs) were observed in soft (0.1 to 1.5 keV) X rays from a rocket. The spectral data of both objects below 1.5 keV are consistent with thermal radiation from a hot plasma and are not consistent with a simple power-law function. Fitting the data to a Tucker-Koren model results in values of T = (4.3 plus or minus 0.3) x 1,000,000 K for Vela and T = (7 plus or minus 1) x 1,000,000 K for Puppis. The present data, earlier data from the Cygnus Loop, and results on Cas A and Tycho reported by others are considered within the context of a simple model in which X rays are thermally produced as a result of a shock wave expanding into the interstellar medium. X-ray data on the temperature, intrinsic diameter, and intrinsic luminosity of the five SNRs are used to compute the age, energy release, and initial interstellar density for each one. From measurements of X-ray absorption along the line of sight, and also from shock-wave model interpretations of temperature-diameter-luminosity relations, it is concluded that the average density of interstellar material is about 0.1 per cu cm between the sun and the nearest X-ray emitting SNR, Vela.

Gorenstein, P.↗
NASA NTRS1974

Radio astronomical determination of ground state transition frequencies of CH

From a comparison of the spectra of CH and other molecules toward the continuum source Cas A and four dark clouds, the ground state transition frequencies of CH have been determined and are reported. The relative errors in these frequencies are about twice as small as those obtained earlier by radio astronomical methods for the two main lines of ground state OH.

Rydbeck, O. E. H.↗