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At least 343 records · Page 19

Adventures in Modern Time Series Analysis: From the Sun to the Crab Nebula and Beyond

With the generation of long, precise, and finely sampled time series the Age of Digital Astronomy is uncovering and elucidating energetic dynamical processes throughout the Universe. Fulfilling these opportunities requires data effective analysis techniques rapidly and automatically implementing advanced concepts. The Time Series Explorer, under development in collaboration with Tom Loredo, provides tools ranging from simple but optimal histograms to time and frequency domain analysis for arbitrary data modes with any time sampling. Much of this development owes its existence to Joe Bredekamp and the encouragement he provided over several decades. Sample results for solar chromospheric activity, gamma-ray activity in the Crab Nebula, active galactic nuclei and gamma-ray bursts will be displayed.

solar chromospheric activity↗

Overview of NASA GRC Stirling Technology Development

The Stirling Radioisotope Generator (SRG) is currently being developed by Lockheed Martin Astronautics (LMA) under contract to the Depar1ment of Energy (DOE). The generator will be a high efficiency electric power source for NASA Space Science missions with the capability to operate in the vacuum of deep space or in an atmosphere such as on the surface of Mars. High system efficiency is obtained through the use of free-piston Stirling power conversion technology. Power output of the generator will be greater than 100 watts at the beginning of life with the decline in power being largely due to the decay of the plutonium heat source. In suppOl1 of the DOE SRG project, the NASA Glenn Research Center (GRC) has established a near-term technology effort to provide some of the critical data to ensure a successful transition to flight for what will be the first dynamic power system used in space. Initially, a limited number of technical areas were selected for the GRC effort, however this is now being expanded to more thoroughly cover a range of technical issues. The tasks include in-house testing of Stirling convertors and controllers, materials evaluation and heater head life assessment, structural dynamics, electromagnetic interference, organics evaluation, and reliability analysis. Most of these high-level tasks have several subtasks within. There is also an advanced technology effort that is complementary near-term technology effort. Many of the tests make use of the 55-We Technology Demonstration Convel10r (TDC). There have been multiple controller tests to support the LMA flight controller design effort. Preparation is continuing for a thermal/vacuum system demonstration. A pair of flight prototype TDC's have recently been placed on an extended test with unattended, continuous operation. Heater head life assessment efforts continue, with the material data being refined and the analysis moving toward the system perspective. Long-term magnet aging tests are continuing to characterize any possible aging in the strength or demagnetization resistance of the permanent magnets used in the linear alternator. In a parallel effort, higher performance magnets are also being evaluated. A reliability effort is being initiated that will help to guide the development activities with an increased focus on the necessary components and subsystems. Some other disciplines that are active in the GRC technology effort include structural dynamics, linear alternator analysis, EMI/EMC, controls, and mechanical design evaluation. This paper will provide an overview of some of the GRC technical efforts, including the current status, and a description of future efforts.

Schreiber, Jeffrey↗

Demographic drivers of gut microbiome diversity

Abstract The gut microbiome plays a central role in orchestrating metabolic, immune, and neurological functions essential for human health. While extensive research has explored the effects of diseases and pathological conditions on gut microbiome composition, the influence of demographic factors remains underexplored, limiting our understanding of microbiome variations in disease states. This study addresses this gap by investigating the impact of demographic variables, including age, sex, and geography, on gut microbiome diversity in healthy individuals. Using the American Gut Project’s extensive dataset and the QIIME2 bioinformatics pipeline, we conducted a comprehensive analysis of microbial profiles across diverse demographic groups. Our results revealed significant age-related shifts in microbial richness and composition, and geographic location strongly influenced phylogenetic diversity. In contrast, sex exhibited limited impact on microbial diversity within healthy BMI ranges. These findings highlight the critical role of demographic factors in shaping gut microbiome diversity, providing a foundational framework to better contextualize disease-related microbiome variations and advance personalized healthcare approaches.

Biotechnology & Applied Microbiology↗

High resolution magnetic resonance imaging of the calcaneus: age-related changes in trabecular structure and comparison with dual X-ray absorptiometry measurements

A high-resolution magnetic resonance imaging (MRI) protocol, together with specialized image processing techniques, was applied to the quantitative measurement of age-related changes in calcaneal trabecular structure. The reproducibility of the technique was assessed and the annual rates of change for several trabecular structure parameters were measured. The MR-derived trabecular parameters were compared with calcaneal bone mineral density (BMD), measured by dual X-ray absorptiometry (DXA) in the same subjects. Sagittal MR images were acquired at 1.5 T in 23 healthy women (mean age: 49.3 +/- 16.6 [SD]), using a three-dimensional gradient echo sequence. Image analysis procedures included internal gray-scale calibration, bone and marrow segmentation, and run-length methods. Three trabecular structure parameters, apparent bone volume (ABV/TV), intercept thickness (I.Th), and intercept separation (I.Sp) were calculated from the MR images. The short- and long-term precision errors (mean %CV) of these measured parameters were in the ranges 1-2% and 3-6%, respectively. Linear regression of the trabecular structure parameters vs. age showed significant correlation: ABV/TV (r2 = 33.7%, P < 0.0037), I.Th (r2 = 26.6%, P < 0.0118), I.Sp (r2 = 28.9%, P < 0.0081). These trends with age were also expressed as annual rates of change: ABV/TV (-0.52%/year), I.Th (-0.33%/year), and I.Sp (0.59%/year). Linear regression analysis also showed significant correlation between the MR-derived trabecular structure parameters and calcaneal BMD values. Although a larger group of subjects is needed to better define the age-related changes in trabecular structure parameters and their relation to BMD, these preliminary results demonstrate that high-resolution MRI may potentially be useful for the quantitative assessment of trabecular structure.

NASA Discipline Number 26-10↗

Chromosome-level genome assembly of Quercus variabilis provides insights into the molecular mechanism of cork thickness

Quercus variabilis is a deciduous woody species with high ecological and economic value and is a major source of cork in East Asia. Cork from thick softwood sheets have higher commercial value than those from thin sheets. It is extremely difficult to genetically improve Q. variabilis to produce high quality softwood due to the lack of genomic information. Here, we present a high-quality chromosomal genome assembly for Q. variabilis with length of 791,89 Mb and 54,606 predicted genes. Comparative analysis of protein sequences of Q. variabilis with 11 other species revealed that specific and expanded gene families were significantly enriched in the "fatty acid biosynthesis" pathway in Q. variabilis, which may contribute to the formation of its unique cork. Additionally, based on weighted correlation network analysis of time-course (i.e., five important developmental ages) gene expression data in thick-cork versus thin-cork genotypes of Q. variabilis, we identified one co-expression gene module associated with the thick-cork trait. Within this co-expression gene module, 10 hub genes were associated with suberin biosynthesis. Furthermore, we identified a total of 198 suberin biosynthesis-related new candidate genes that were up-regulated in trees with a thick cork layer relative to those with a thin cork layer. Also, we found that some genes related to cell expansion and cell division were highly expressed in trees with a thick cork layer. Collectively, our results revealed that two metabolic pathways (i.e., suberin biosynthesis, fatty acid biosynthesis), along with other genes involved in cell expansion, cell division, and transcriptional regulation, were associated with the thick-cork trait in Q. variabilis, providing insights into the molecular basis of cork development and knowledge for informing genetic improvement of cork thickness in Q. variabilis and closely related species.

59 BASIC BIOLOGICAL SCIENCES↗

Photogeology of the dark material in the Taurus-Littrow region of the moon

Regional relations and characteristics of the dark material as observed on photographs of the Taurus-Littrow region of the moon are reviewed to provide a background for interpretations of its nature and origin. The dark material seems to be a surficial deposit that covers mare and highland areas near the southeastern edge of the Serenitatis Basin. The age of the dark material, as deduced from photogeologic analysis, is ambiguous: contact relations near its western edge suggest that it is older than the central light basalts of Mare Serenitatis; evidence elsewhere indicates that it may be younger. The origin of the dark material is also uncertain, and the following alternate hypotheses are briefly considered: (1) thick regolith, (2) dark impact ejecta, (3) pyroclastic blanket, or (4) a material of different origin in different places.

Lucchitta, B. K.↗

Tectonic, volcanic, and climatic geomorphology study of the Sierras Pampeanas Andes, northwestern Argentina

A proposed analysis of Shuttle Imaging Radar-B (SIR-B) data extends current research in the Sierras Pampeanas and the Puna of northwestern Argentina to the determination - by the digital analysis of mountain-front sinuousity - of the relative age and amount of fault movement along mountain fronts of the late-Cenozoic Sierras Pampeanas basement blocks; the determination of the age and history of the boundary across the Andes at about 27 S latitude between continuing volcanism to the north and inactive volcanism to the south; and the determination of the age and extent of Pleistocene glaciation in the High Sierras, as well as the comparative importance of climatic change and tectonic movements in shaping the landscape. The integration of these studies into other ongoing geology projects contributes to the understanding of landform development in this active tectonic environment and helps distinguish between climatic and tectonic effects on landforms.

Bloom, A. L.↗

Chemically Derived Dense Alumina-Zirconia Composites for Improved Mechanical and Wear Erosion Properties

As a result of this funded project high purity Zirconia-Toughened Alumina (ZTA) ceramic powders with and without yttria were produced using metal alkoxide precursors. ZTA ceramic powders with varying volume percents of zirconia were prepared (7, 15, and 22%). Aluminum tri-sec butoxide, zirconium propoxide, and yttrium isopropoxide were the reagents used. Synthesis conditions were varied to control the hydrolysis and the aging conditions for the sol to gel transition. FTIR analysis and rheological characterization were used to follow the structural evolution during the sol to gel transition. The greater extent of hydrolysis and the build-up of structure measured from viscoelastic properties were consistent. Heat treatment was conducted to produce submicron grain fully crystalline ZTA ceramic powders. This improved materials should have enhanced properties such strength, toughness, and wear resistance for advanced structural applications, for example engine components in high technology aerospace applications.

Source record↗

Characterization of the Sol-Gel Transition for Zirconia-Toughened Alumina Precursors

High purity ZTA ceramic powders with and without yttria were produced using metal alkoxide precursors. ZTA ceramic powders with varying volume percents of zirconia were prepared (7, 15, and 22%). Aluminum tri-sec butoxide, zirconium propoxide, and yttrium isopropoxide were the reagents used. Synthesis conditions were varied to control the hydrolysis and the aging conditions for the sol to gel transition. FTIR analysis and theological characterization were used to follow the structural evolution during the sol to gel transition. The greater extent of hydrolysis and the build-up of structure measured from viscoelastic properties were consistent. Heat treatment was conducted to produce submicron grain fully crystalline ZTA ceramic powders. In all experimental cases a-alumina and tetragonal zirconia phases were confirmed even in the absence of yttria.

Moeti, I.↗

Planetary Geology and Geophysics Program

Geological mapping and topical studies, primarily in the southern Acidalia Planitia/Cydonia Mensae region of Mars is presented. The overall objective was to understand geologic processes and crustal history in the northern lowland in order to assess the probability that an ocean once existed in this region. The major deliverable is a block of 6 1:500,000 scale geologic maps that will be published in 2004 as a single map at 1:1,000,000 scale along with extensive descriptive and interpretive text. A major issue addressed by the mapping was the relative ages of the extensive plains of Acidalia Planitia and the knobs and mesas of Cydonia Mensae. The mapping results clearly favor a younger age for the plains. Topical studies included a preliminary analysis of the very abundant small domes and cones to assess the possibility that their origins could be determined by detailed mapping and remote-sensing analysis. We also tested the validity of putative shorelines by using GIs to co-register full-resolution MOLA altimetry data and Viking images with these shorelines plotted on them. Of the 3 proposed shorelines in this area, one is probably valid, one is definitely not valid, and the third is apparently 2 shorelines closely spaced in elevation. Publications supported entirely or in part by this grant are included.

McGill, George E.↗

Non-Destructive Evaluation of Wire Insulation and Coatings

The present invention uses the generation and detection of acoustic guided waves to evaluate the condition of the insulation on electrical wiring. Low order axisymmetric and flexural acoustic modes are generated in the insulated wire and travel partially in the center conductor and partially in the outer insulation. The stiffness of the insulation and the insulation's condition affect the overall wave speed and amplitude of the guided wave. Analysis of the received signal provides information about the age or useful life of the wire insulation. In accordance with the present invention, signal transmission occurs at one location on the electrical wire to be evaluated, and detection occurs at one or more locations along the electrical wire. Additional receivers can be used to improve measurement accuracy. Either the transmission transducer or one or more receiver transducers may be angled at other than 90 degrees to the wire. Generation of the guided waves can be accomplished by imparting a pressure pulse on the wire. Alternative embodiments include generation via a laser, such as a Q-switched laser or a laser diode.

Eric I Madaras↗

Discrete X-Ray Source Populations and Star Formation History in Nearby Galaxies

This program aims in understanding the connection between the discrete X-ray source populations observed in nearby galaxies and the history of star-formation in these galaxies. The ultimate goal is to use this knowledge in order to constrain X-ray binary evolution channels. For this reason although the program is primarily observational it has a significant modeling component. During the second year of this study we focused on detailed studies of the Antennae galaxies and the Small Magellanic Cloud (SMC). We also performed the initial analysis of the 5 galaxies forming a starburst-age sequence.

Zezas, Andreas↗

Nondestructive Methods and Special Test Instrumentation Supporting NASA Composite Overwrapped Pressure Vessel Assessments

Many aging composite overwrapped pressure vessels (COPVs), being used by the National Aeronautics and Space Administration (NASA) are currently under evaluation to better quantify their reliability and clarify their likelihood of failure due to stress rupture and age-dependent issues. As a result, some test and analysis programs have been successfully accomplished and other related programs are still in progress at the NASA Johnson Space Center (JSC) White Sands Test Facility (WSTF) and other NASA centers, with assistance from the commercial sector. To support this effort, a group of Nondestructive Evaluation (NDE) experts was assembled to provide NDE competence for pretest evaluation of test articles and for application of NDE technology to real-time testing. Techniques were required to provide assurance that the test article had adequate structural integrity and manufacturing consistency to be considered acceptable for testing and these techniques were successfully applied. Destructive testing is also being accomplished to better understand the physical and chemical property changes associated with progression toward "stress rupture" (SR) failure, and it is being associated with NDE response, so it can potentially be used to help with life prediction. Destructive work also includes the evaluation of residual stresses during dissection of the overwrap, laboratory evaluation of specimens extracted from the overwrap to evaluate physical property changes, and quantitative microscopy to inform the theoretical micromechanics.

Saulsberry, Regor↗

Martian Chronology and Atmospheric Composition: In Situ Measurements versus Sample Return

I examine two significant issues of martian science from the point of view of in situ measurements by robotic spacecraft versus sample return and analysis in terrestrial labs. (1) To define martian history, ages of geological processes and surface features are required. Estimated ages from surface crater densities have limitations, and the ages measured for martian meteorites cannot be associated with specific martian locales. Whereas returned martian rocks could be accurately dated, some have suggested sending a robotic spacecraft to Mars to measure rock ages using the classical K- Ar-40 technique, considered the easiest to implement. (2) To understand the evolution of the martian atmosphere and its interactions with the surface, requires precise measurements of atmospheric composition. A significant amount of information has derived from measurements by Viking and of martian meteorites. Instrumentation on the Mars Science Lander (MSL) spacecraft to be launched in the near future promises to determine atmospheric composition even more precisely. If MSL is successful, which questions about atmospheric composition will remain and thus will require atmospheric sample return to answer?

Bogard, Donald D.↗

Mapping Pine Plantations in the Southeastern U.S. Using Structural, Spectral, and Temporal Remote Sensing Data

The southeastern U.S. produces the most industrial roundwood in the U.S. each year, largely from commercial pine plantations. The extent of plantation forests and management dynamics can be difficult to ascertain from periodic forest inventories, yet short-rotation tree plantations also present challenges for remote sensing. Here, we integrated spectral, temporal, and structural information from airborne and satellite platforms to distinguish pine plantations from natural forests and evaluate the contribution from planted forests to regional forest coverin the southeastern U.S. Within flight lines from NASA Goddard's Lidar, Hyperspectral, and Thermal (G-LiHT) Airborne Imager, lidar metrics of forest structure had the highest overall accuracy for pine plantations among single-source classifications (90%), but the combination of spectral and temporal metrics from Landsat generated comparable accuracy (91%). Combined structural, temporal, and spectral information from G-LiHT and Landsat had the highest accuracy for plantations (92%) and natural forests (88%). At a regional scale, classifications using Landsat spectral and temporal metrics had between 74 and 82% mean class accuracy for plantations.Regionally, plantations accounted for 28% of forest cover in the southeastern U.S., a result similar to plot-based estimates, albeit with greater spatial detail. Regional maps of plantation forests differed from existing map products, including the National Land Cover Database. Combining plantation extent in 2011 with Landsat based forest change data identified strong regional gradients in plantation dynamics since 1985, with distinct spatial patterns of rotation age (east-west) and plantation expansion (interior). Our analysis demonstrates the potential to improve the characterization of dynamic land cover classes, including economically important timber plantations, by integrating diverse remote sensing datasets. Critically, multi-source remote sensing provides an approach to leverage periodic forest inventory data for annual monitoring of managed forest landscapes.

Fagan, M. E.↗

The evolution of chromospheric activity and the spin-down of solar-type stars

IUE data for 31 solar-type stars are compared with observations of T Tauri stars in order to determine whether the pattern of main sequence chromospheric decay shown by stars older than about 100 million yr extends back to ages of 100 million yr appropriate for T Tauri stars. An analysis of the time decay of stellar ultraviolet and X-ray emission establishes a relationship between emission level and axial rotation, which is expressed in terms of the Rossby parameter. It is shown that the intensity of ultraviolet chromospheric and transition region lines of solar-type stars declines with age. The activity-age relation for main sequence stars older than about 100 million yr is fitted best by an exponential law whose rate of falloff with age depends on temperature.

Simon, T.↗

Efficacy of Dried Plum to Countermeasure Simulated Spaceflight Exposure

Human exploration of the space environment has been a topic of interest for decades; however, the threat to physiological health posed by ionizing radiation and microgravity effects remains a concern. Previous research utilizing combined hindlimb unloading and irradiation to simulate spaceflight effects found that a dried plum diet can mitigate adverse effects of simulated spaceflight on skeletal health. Though the mechanism is not fully understood we believe this protective effect is due to its high antioxidant capacity and polyphenolic content. This study seeks to extend these findings to investigate if dried plum is an effective countermeasure in other tissues relating to aging and neurotoxicity. Male C57BL/6 J mice were assigned to one of eight groups (n = 10/group) and were fed either a controlled diet or dried plum diet, underwent normal loading or hindlimb unloading as well as exposure 2 Gy gamma radiation or sham exposure. At the end of the experiment, mice were euthanized, and RNA was extracted from brain and bone marrow tissue and PCR was employed to analyze significant changes in gene expression profiles. Analysis of five house-keeping genes revealed genes B2M (neurotoxicity) and GUSB (aging) to be the most stable genes across all treatments and were used to find the fold change within our genes of interest. Through this, and analysis via ANOVA, we were able to identify genes with significant altered expression levels within brain and bone marrow tissues related to neurotoxicity and aging. Considering previous research, we hypothesize that the dried plum diet’s antioxidative properties ameliorated the oxidative stress from irradiation and microgravity via altered levels of gene expression. Identified expression changes will provide insights into molecular mechanisms behind the observed protective effects. These findings present potential avenues for future interventions to alleviate negative impacts of spaceflight on astronaut health.

Faisal Ahmad↗

The Efficacy of Dried Plum to Counter Spaceflight Microgravity and Radiation

Human exploration of the space environment has been a topic of interest for decades; however, the threat to physiological health posed by ionizing radiation and microgravity effects remains a concern. Previous research utilizing combined hindlimb unloading and irradiation to simulate spaceflight effects found that a dried plum diet can mitigate adverse effects of simulated spaceflight on skeletal health. Though the mechanism is not fully understood we believe this protective effect is due to its high antioxidant capacity and polyphenolic content. This study seeks to extend these findings to investigate if dried plum is an effective countermeasure in other tissues relating to aging and neurotoxicity. Male C57BL/6 J mice were assigned to one of eight groups (n = 10/group) and were fed either a controlled diet or dried plum diet, underwent normal loading or hindlimb unloading as well as exposure 2 Gy gamma radiation or sham exposure. At the end of the experiment, mice were euthanized, and RNA was extracted from brain and bone marrow tissue and PCR was employed to analyze significant changes in gene expression profiles. Analysis of five house-keeping genes revealed genes B2M (neurotoxicity) and GUSB (aging) to be the most stable genes across all treatments and were used to find the fold change within our genes of interest. Through this, and analysis via ANOVA, we were able to identify genes with significant altered expression levels within brain and bone marrow tissues related to neurotoxicity and aging. Considering previous research, we hypothesize that the dried plum diet’s antioxidative properties ameliorated the oxidative stress from irradiation and microgravity via altered levels of gene expression. Identified expression changes will provide insights into molecular mechanisms behind the observed protective effects. These findings present potential avenues for future interventions to alleviate negative impacts of spaceflight on astronaut health.

Faisal Ahmad↗