Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “support effects”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 325 records · Page 18
All sourcesNASA NTRSDOE OSTI
NASA NTRS1996

Comparative effects of contraction and angiotensin II on growth of adult feline cardiocytes in primary culture

The purposes of this study were 1) to determine whether angiotensin II causes growth of adult feline cardiocytes in long-term culture, 2) to compare the growth effects of angiotensin II with those resulting from electrically stimulated contraction, and 3) to determine whether the anabolic effects of contraction are exerted via the angiotensin type 1 receptor. Adult feline cardiocytes were cultured on laminin-coated trays in a serum-free medium. Cardiocytes were either electrically stimulated to contract (1 Hz, 5-ms pulse duration, alternating polarity) or were nonstimulated and quiescent. Quiescent cells were studied as controls and after treatment with angiotensin II (10(-8) M), losartan (10(-6) M; an angiotensin type 1-receptor antagonist), or angiotensin II plus losartan. Contracting cells were studied in the presence and absence of angiotensin II or losartan. In quiescent cardiocytes, angiotensin II treatment on day 7 significantly increased protein synthesis rates by 22% and protein content per cell by 17%. The effects of angiotensin II were completely blocked by losartan. Electrically stimulated contraction on days 4 and 7 in culture significantly increased protein synthesis rate by 18 and 38% and protein content per cell by 19 and 46%, respectively. Angiotensin II treatment did not further increase protein synthesis rate or protein content in contracting cardiocytes. Furthermore, losartan did not block the anabolic effects of contraction on protein synthesis rates or protein content. In conclusion, angiotensin II can exert a modest anabolic effect on adult feline cardiocytes in culture. In contracting feline cardiocytes, angiotensin II has no effect on growth. Growth caused by electrically stimulated contraction occurs more rapidly and is greater in magnitude than that caused by angiotensin II. Growth of contracting adult feline cardiocytes is not dependent on activation of the angiotensin receptor.

NASA Discipline Cardiopulmonary↗
NASA NTRS1996

Dose equivalent near the bone-soft tissue interface from nuclear fragments produced by high-energy protons

During manned space missions, high-energy nucleons of cosmic and solar origin collide with atomic nuclei of the human body and produce a broad linear energy transfer spectrum of secondary particles, called target fragments. These nuclear fragments are often more biologically harmful than the direct ionization of the incident nucleon. That these secondary particles increase tissue absorbed dose in regions adjacent to the bone-soft tissue interface was demonstrated in a previous publication. To assess radiological risks to tissue near the bone-soft tissue interface, a computer transport model for nuclear fragments produced by high energy nucleons was used in this study to calculate integral linear energy transfer spectra and dose equivalents resulting from nuclear collisions of 1-GeV protons transversing bone and red bone marrow. In terms of dose equivalent averaged over trabecular bone marrow, target fragments emitted from interactions in both tissues are predicted to be at least as important as the direct ionization of the primary protons-twice as important, if recently recommended radiation weighting factors and "worst-case" geometry are used. The use of conventional dosimetry (absorbed dose weighted by aa linear energy transfer-dependent quality factor) as an appropriate framework for predicting risk from low fluences of high-linear energy transfer target fragments is discussed.

NASA Discipline Number 45-10↗
NASA NTRS1996

Clusters of DNA induced by ionizing radiation: formation of short DNA fragments. I. Theoretical modeling

We have developed a general theoretical model for the interaction of ionizing radiation with chromatin. Chromatin is modeled as a 30-nm-diameter solenoidal fiber comprised of 20 turns of nucleosomes, 6 nucleosomes per turn. Charged-particle tracks are modeled by partitioning the energy deposition between primary track core, resulting from glancing collisions with 100 eV or less per event, and delta rays due to knock-on collisions involving energy transfers >100 eV. A Monte Carlo simulation incorporates damages due to the following molecular mechanisms: (1) ionization of water molecules leading to the formation of OH, H, eaq, etc.; (2) OH attack on sugar molecules leading to strand breaks: (3) OH attack on bases; (4) direct ionization of the sugar molecules leading to strand breaks; (5) direct ionization of the bases. Our calculations predict significant clustering of damage both locally, over regions up to 40 bp and over regions extending to several kilobase pairs. A characteristic feature of the regional damage predicted by our model is the production of short fragments of DNA associated with multiple nearby strand breaks. The shapes of the spectra of DNA fragment lengths depend on the symmetries or approximate symmetries of the chromatin structure. Such fragments have subsequently been detected experimentally and are reported in an accompanying paper (B. Rydberg, Radiat, Res. 145, 200-209, 1996) after exposure to both high- and low-LET radiation. The overall measured yields agree well quantitatively with the theoretical predictions. Our theoretical results predict the existence of a strong peak at about 85 bp, which represents the revolution period about the nucleosome. Other peaks at multiples of about 1,000 bp correspond to the periodicity of the particular solenoid model of chromatin used in these calculations. Theoretical results in combination with experimental data on fragmentation spectra may help determine the consensus or average structure of the chromatin fibers in mammalian DNA.

Non-NASA Center↗
NASA NTRS1995

A calcium-permeable cGMP-activated cation conductance in hippocampal neurons

Whole-cell patch clamp recordings detected a previously unidentified cGMP-activated membrane conductance in cultured rat hippocampal neurons. This conductance is nonselectively permeable for cations and is completely but reversibly blocked by external Cd2+. The Ca2+ permeability of the hippocampal cGMP-activated conductance was examined in detail, indicating that the underlying ion channels display a high relative permeability for Ca2+. The results indicate that hippocampal neurons contain a cGMP-activated membrane conductance that has some properties similar to the cyclic nucleotide-gated channels previously shown in sensory receptor cells and retinal neurons. In hippocampal neurons this conductance similarly could mediate membrane depolarization and Ca2+ fluxes in response to intracellular cGMP elevation.

Non-NASA Center↗
NASA NTRS1993

Hair cell regeneration in the bullfrog vestibular otolith organs following aminoglycoside toxicity

Adult bullfrog were given single intraotic injections of the aminoglycoside antibiotic gentamicin sulfate and sacrificed at postinjection times ranging from 0.5 to 9 days. The saccular and utricular maculae of normal and injected animals were examined in wholemount and cross-section. Intraotic 200 microM gentamicin concentrations resulted in the uniform destruction of the hair bundles and, at later times, the cell bodies of saccular hair cells. In the utriculus, striolar hair cells were selectively damaged while extrastriolar hair cells were relatively unaffected. Regenerating hair cells, identified in sectioned material by their small cell bodies and short, well-formed hair bundles, were seen in the saccular and utricular maculae as early as 24-48 h postinjection. Immature versions of mature hair cell types in both otolith organs were recognized by the presence or absence of a bulbed kinocilia and the relative lengths of their kinocilia and longest stereocilia. Utricular hair cell types with kinocilia longer than their longest stereocilia were observed at earlier than hair cell types with shorter kinocilia. In the sacculus, the hair bundles of gentamicin-treated animals, even at 9 days postinjection, were significantly smaller than those of normal animals. The hair bundles of utricular hair cells, on the other hand, reached full maturity within the same time period.

NASA Discipline Neuroscience↗
NASA NTRS2004

Navier-Stokes Computations of Longitudinal Forces and Moments for a Blended Wing Body

The object of this paper is to investigate the feasibility of applying CFD methods to aerodynamic analyses for aircraft stability and control. The integrated aerodynamic parameters used in stability and control, however, are not necessarily those extensively validated in the state of the art CFD technology. Hence, an exploratory study of such applications and the comparison of the solutions to available experimental data will help to assess the validity of the current computation methods. In addition, this study will also examine issues related to wind tunnel measurements such as measurement uncertainty and support interference effects. Several sets of experimental data from the NASA Langley 14x22-Foot Subsonic Tunnel and the National Transonic Facility are presented. Two Navier-Stokes flow solvers, one using structured meshes and the other unstructured meshes, were used to compute longitudinal static stability derivatives for an advanced Blended Wing Body configuration over a wide range of angles of attack. The computations were performed for two different Reynolds numbers and the resulting forces and moments are compared with the above mentioned wind tunnel data.

Pao, S. Paul↗
NASA NTRS2005

Navier-Stokes Computations of Longitudinal Forces and Moments for a Blended Wing Body

The object of this paper is to investigate the feasibility of applying CFD methods to aerodynamic analyses for aircraft stability and control. The integrated aerodynamic parameters used in stability and control, however, are not necessarily those extensively validated in the state of the art CFD technology. Hence, an exploratory study of such applications and the comparison of the solutions to available experimental data will help to assess the validity of the current computation methods. In addition, this study will also examine issues related to wind tunnel measurements such as measurement uncertainty and support interference effects. Several sets of experimental data from the NASA Langley 14x22-Foot Subsonic Tunnel and the National Transonic Facility are presented. Two Navier-Stokes flow solvers, one using structured meshes and the other unstructured meshes, were used to compute longitudinal static stability derivatives for an advanced Blended Wing Body configuration over a wide range of angles of attack. The computations were performed for two different Reynolds numbers and the resulting forces and moments are compared with the above mentioned wind tunnel data.

Pao, S. Paul↗
NASA NTRS2002

Network issues

In this paper we review the IGS network as it currently exists and its effectiveness in supporting the IGS suite of precise products.

International GPD Service GPS network space geodes↗
NASA NTRS2007

Microbial Extremophiles in Aspect of Limits of Life

During Earth's evolution accompanied by geophysical and climatic changes a number of ecosystems have been formed. These ecosystems differ by the broad variety of physicochemical and biological factors composing our environment. Traditionally, pH and salinity are considered as geochemical extremes, as opposed to the temperature, pressure and radiation that are referred to as physical extremes (Van den Burg, 2003). Life inhabits all possible places on Earth interacting with the environment and within itself (cross species relations). In nature it is very rare when an ecotope is inhabited by a single species. As a rule, most ecosystems contain the functionally related and evolutionarily adjusted communities (consortia and populations). In contrast to the multicellular structure of eukaryotes (tissues, organs, systems of organs, whole organism), the highest organized form of prokaryotic life in nature is the benthic colonization in biofilms and microbial mats. In these complex structures all microbial cells of different species are distributed in space and time according to their functions and to physicochemical gradients that allow more effective system support, self-protection, and energy distribution. In vitro, of course, the most primitive organized structure for bacterial and archaeal cultures is the colony, the size, shape, color, consistency, and other characteristics of which could carry varies specifics on species or subspecies levels. In table 1 all known types of microbial communities are shown (Pikuta et a]., 2005). In deep underground (lithospheric) and deep-sea ecosystems an additional factor - pressure, and irradiation - could also be included in the list of microbial communities. Currently the beststudied ecosystems are: human body (due to the medical importance), and fresh water and marine ecosystems (due to the reason of an environmental safety). For a long time, extremophiles were terra incognita, since the environments with aggressive parameters (compared to the human body temperature, pH, mineralization, and pressure) were considered a priori as a dead zone.

Pikuta, Elena V.↗
NASA NTRS2010

Using Facility Condition Assessments to Identify Actions Related to Infrastructure

To support cost effective, quality research it is essential that laboratory and testing facilities are maintained in a continuous and reliable state of availability at all times. NASA Langley Research Center (LaRC) and its maintenance contractor, Jacobs Technology, Inc. Research Operations, Maintenance, and Engineering (ROME) group, are in the process of implementing a combined Facility Condition Assessment (FCA) and Reliability Centered Maintenance (RCM) program to improve asset management and overall reliability of testing equipment in facilities such as wind tunnels. Specific areas are being identified for improvement, the deferred maintenance cost is being estimated, and priority is being assigned against facilities where conditions have been allowed to deteriorate. This assessment serves to assist in determining where to commit available funds on the Center. RCM methodologies are being reviewed and enhanced to assure that appropriate preventive, predictive, and facilities/equipment acceptance techniques are incorporated to prolong lifecycle availability and assure reliability at minimum cost. The results from the program have been favorable, better enabling LaRC to manage assets prudently.

Rubert, Kennedy F.↗
NASA NTRS2011

Summary of the First AIAA CFD High Lift Prediction Workshop (invited)

The 1st AIAA CFD High Lift Prediction Workshop was held in Chicago in June 2010. The goals of the workshop included an assessment of the numerical prediction capability of current-generation CFD technology/ codes for swept, medium/high-aspect ratio wings in landing/take-off (high lift) configurations. 21 participants from 8 countries and 18 organizations, submitted a total of 39 datasets of CFD results. A variety of grid systems (both structured and unstructured) were used. Trends due to flap angle were analyzed, and effects of grid family, grid density, solver, and turbulence model were addressed. Some participants also assessed the effects of support brackets used to attach the flap and slat to the main wing. This invited paper describes the combined results from all workshop participants. Comparisons with experimental data are made. A statistical summary of the CFD results is also included.

Rumsey, C. L.↗
NASA NTRS2011

An Analysis of Near Fields of 34m Antennas of JPL/NASA Deep Space Network

This paper addresses the issue of calculating near fields of the 34m Beam Waveguide (BWG) antennas of the NASA/JPL Deep Space Network (DSN). Calculating the near fields of DSN antennas are of interest in receive mode where the transmitting signals from nearby flying objects such as helicopters and airplanes could interfere with the operation of sensitive RF receiving system of DSN antennas, and in the transmit mode where fields from high-powered DSN antennas interfere with receivers on nearby flying objects, as well as safety considerations for the operators and visitors to the grounds surrounding the antenna sites. A complete and detailed analysis has been performed using PO/PTD techniques, including surface errors and support struts effects. Some results are presented, including comparisons with preliminary field tests.

near fields↗
NASA NTRS2014

Overview and Summary of the Second AIAA High Lift Prediction Workshop

The second AIAA CFD High-Lift Prediction Workshop was held in San Diego, California, in June 2013. The goals of the workshop continued in the tradition of the first high-lift workshop: to assess the numerical prediction capability of current-generation computational fluid dynamics (CFD) technology for swept, medium/high-aspect-ratio wings in landing/takeoff (high-lift) configurations. This workshop analyzed the flow over the DLR-F11 model in landing configuration at two different Reynolds numbers. Twenty-six participants submitted a total of 48 data sets of CFD results. A variety of grid systems (both structured and unstructured) were used. Trends due to grid density and Reynolds number were analyzed, and effects of support brackets were also included. This paper analyzes the combined results from all workshop participants. Comparisons with experimental data are made. A statistical summary of the CFD results is also included.

Rumsey, Christopher L.↗
NASA NTRS2017

NASA's Ground-Based Observing Campaigns of Rocket Bodies with the UKIRT and NASA ES-MCAT Telescopes

Rocket bodies comprise a class of human-made space debris that are at the same time essential for launching every spacecraft from the Earth, but are also a significant source of debris both as intact objects, as well as fragmented debris. Unspent fuel has been long theorized as a potential cause of catastrophic rocket body break-ups. Given typical orbital speeds range from approximately 2-3 kilometers per second at Geosynchronous Orbit (GEO) and up to 15 kilometers per second in low Earth orbit (LEO), collisions with uncatalogued and undetected debris can also cause catastrophic breakups. Understanding break-ups is a necessary step in preventing them, and one key step in that process is to correlate and characterize daughter fragments with their parent bodies. Two very different methods include (1) conducting photometric surveys to correlate an object's motion and orbital elements to the parent body, and (2) characterizing what materials comprise the target to determine whether those materials are consistent with the parent body or like objects. With this in mind, photometric data were taken shortly after the breakup of one rocket body for short-term orbital studies, and a suite of spectral data were taken of rocket bodies that are fully intact to compare with debris, for characterization studies. Targets included Titan Transtage, Briz-M, and Ariane rocket bodies and debris. Spectra of each sub-class of rocket body were very similar within their rocket body type, but differed distinctly from one type to the next, supporting the effectiveness of this approach.

Lederer, Susan M.↗
NASA NTRS2017

A MODIS-Based Automated Flood Monitoring System for Southeast Asia

Flood disasters in Southeast Asia result in significant loss of life and economic damage. Remote sensing information systems designed to spatially and temporally monitor floods can help governments and international agencies formulate effective disaster response strategies during a flood and ultimately alleviate impacts to population, infrastructure, and agriculture. Recent destructive flood events in the Lower Mekong River Basin occurred in 2000, 2011, 16 2013, and 2016 (http://ffw.mrcmekong.org/historical_rec.htm, April 24, 2017). The large spatial distribution of flooded areas and lack of proper gauge data in the region makes accurate monitoring and assessment of impacts of floods difficult. Here, we discuss the utility of applying satellite-based Earth observations for improving flood inundation monitoring over the flood-prone Lower Mekong River Basin. We present a methodology for determining near real-time surface water extent associated with current and historic flood events by training surface water classifiers from 8-day, 250-meter Moderate-resolution Imaging Spectroradiometer (MODIS) data spanning the length of the MODIS satellite record. The Normalized Difference Vegetation Index (NDVI) signature of permanent water bodies (MOD44W; Carroll et al., 2009) is used to train surface water classifiers which are applied to a time period of interest. From this, an operational nowcast flood detection component is produced using twice daily imagery acquired at 3-hour latency which performs image compositing routines to minimize cloud cover. Case studies and accuracy assessments against radar-based observations for historic flood events are presented. The customizable system has been transferred to regional organizations and near real-time derived surface water products are made available through a web interface platform. Results highlight the potential of near real-time observation and impact assessment systems to serve as effective decision support tools for governments, international agencies, and disaster responders.

Mekong River↗
NASA NTRSDate not supplied

Using Weather-Based Irrigation Scheduling to Optimize Red Cabbage Production

A replicated field trial was performed on a Chualar sandy loam in California’s Salinas Valley during 2020 to investigate the yield response of drip-irrigated red cabbage to applied water volume. The crop was transplanted on 29-April and established with approximately 4 inches of water uniformly applied by overhead sprinklers. At 22 days after transplanting (DAT), five drip-irrigation treatments were established at 50, 75, 100, 125, and 150% of estimated daily crop evapotranspiration (ETc). The treatments were replicated 6 times following a randomized complete block design. The 100% crop water requirement was specified by CropManage, an irrigation scheduling application that combines a crop coefficient approach with reference evapotranspiration data from the California Irrigation Management Information System. The crop was irrigated 3 times per week. Nitrogen fertilizer, totaling 320 lbs/ac, was applied through the drip system once per week. Commercial carton yields were evaluated 85 DAT. The 100% ETc treatment received a total of 18.3 inches of water including sprinkler establishment and had the highest yield at 57 tons/ac, while the 50% treatment (11.5 inches) yielded a low of 32 tons/ac. For reference, average applied water reported for this crop on the Central Coast is about 22.5 inches by way of a variety of irrigation methods including drip, sprinkler, and furrow. Aboveground biomass was evaluated 91 DAT. The 100% treatment had the highest fresh (105 tons/ac) and dry (7.7 tons/ac) biomass yield. Commercial bulk yields at 98 DAT and were maximized by 20-24 inches of water (100%, 125% treatments) and ranged from a high of 67 tons/ac for 125% ETc treatment (24.3 inches of water) to 35 tons/ac for the 50% treatment (12.6 inches). The results demonstrated that yield and quality targets for this crop can be met by drip irrigation, and CropManage is an effective decision support tool for evaluating crop water requirements based on weather data.

Weather-Based↗
NASA NTRS1977

Finite Element Stability Analysis for Coupled Rotor and Support Systems

The effects of fuselage motions on stability and random response were analytically assessed. The feasibility of adequate perturbation models from non-linear trim conditions was studied by computer and hardware experiments. Rotor wake-blade interactions were assessed by using a 4-bladed rotor model with the capability of progressing and regressing blade pitch excitation (cyclic pitch stirring), by using a 4-bladed rotor model with hub tilt stirring, and by testing rotor models in sinusoidal up or side flow.

Hohenemser, K. H.↗