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NASA NTRS1995

Gamma-ray transfer and energy deposition in supernovae

Solutions to the energy-independent (gray) radiative transfer equations are compared to results of Monte Carlo simulations of the Ni-56 and Co-56 decay gamma-ray energy deposition in supernovae. The comparison shows that an effective, purely absorptive, gray opacity, kappa(sub gamma) approximately (0. 06 +/- 0.01)Y(sub e) sq cm/g, where Y is the total number of electrons per baryon, accurately describes the interaction of gamma-rays with the cool supernova gas and the local gamma-ray energy deposition within the gas. The nature of the gamma-ray interaction process (dominated by Compton scattering in the relativistic regime) creates a weak dependence of kappa(sub gamma) on the optical thickness of the (spherically symmetric) supernova atmosphere: The maximum value of kappa(sub gamma) applies during optically thick conditions when individual gamma-rays undergo multiple scattering encounters and the lower bound is reached at the phase characterized by a total Thomson optical depth to the center of the atmosphere tau(sub e) approximately less than 1. Gamma-ray deposition for Type Ia supernova models to within 10% for the epoch from maximum light to t = 1200 days. Our results quantitatively confirm that the quick and efficient solution to the gray transfer problem provides an accurate representation of gamma-ray energy deposition for a broad range of supernova conditions.

Swartz, Douglas A.↗

NASA NTRS1996

[Results of the NASA/University Joint Venture (JOVE) Program at the University of Vermont]

Sea ice parameters in the north and south polar regions are important components of the global climate system. Current air-sea-ice models do not take into account oscillatory behavior in the ice covers other than for the seasonal cycle, since the relative importance of such oscillations is not known. An analysis of oscillatory behavior then becomes important from the standpoints of determining the significance of the various oscillatory components and perhaps discovery of some new aspects of the air-sea-ice interaction processes. One of these components, the El Nino-Southern Oscillation (ENSO) is known to be associated with weather changes on a global scale. Indeed, its spectral components have also been observed in the sea ice distribution in both hemispheres.

Yu, Jun↗

NASA NTRS1998

Global Auroral Imaging for the Dynamics Explorer Mission

The two Dynamics Explorer spacecraft, DE-1 and DE-2, were launched on August 3, 1981, into polar coplanar orbits at different altitudes for the purpose of studying interactive processes within the atmosphere-ionosphere-magnetosphere system. The DE-1 spacecraft (high-altitude mission) used an elliptical orbit that was selected to allow: (1) measurements extending from the hot magnetospheric plasma through the plasmasphere to the cool ionosphere; (2) global auroral imaging, wave measurements in the heart of the magnetosphere, and crossing of auroral field lines at several earth radii; and (3) measurements for significant periods of time along a magnetic field flux tube. The orbit of Dynamics Explorer 1 offered an opportunity to obtain global images of Earth's dayglow and auroral luminosities and to acquire consecutive images of the entire auroral oval during the growth, onset, expansion, and recovery phases of substorms. The University of Iowa's Spin-scan Auroral Imaging (SAI) instrument, was on-board DE-1. SAI was activated in orbit and placed in routine operation on September 23, 1981, and has provided outstanding new contributions in the fields of auroral, magnetospheric and geocoronal physics, introduced a powerful tool for the study of global atmospheric ozone, and initiated the first search from space for marine bioluminescence on the surface of the global ocean. The SAI instrumentation consists of three imaging photometers, two for visible wavelengths and the third for vacuum-ultraviolet wavelengths equipped with primary catoptric optics with superpolished mirror surfaces. The primary focusing element is an off-axis section of a parabolic mirror that is used to provide an optical path completely free of support structures for the mirrors.

Frank, L. A.↗

NASA NTRS1997

Western Pacific Tropospheric Ozone and Potential Vorticity: Implications for Asian Pollution

Tropospheric ozone (03) cross sections measured with lidar from a DC-8 aircraft over the western Pacific correspond closely with potential vorticity (PV). Both are transported from the middle latitude stratosphere, although this is not the only source of 03, and both have sinks in the tropical boundary layer. 03 and PV are good indicators of photochemical and transport process interactions. In summer, some Asian pollution, raised by convection to the upper troposphere, passes southward into the tropics and to the Southern Hemisphere. In winter, subsidence keeps the pollution at low altitudes where it moves over the ocean towards the Inter-Tropical Convergence Zone (ITCZ), with photochemical destruction and secondary pollutant generation occurring en route. Convection raises this modified air to the upper troposphere, where some re may enter the stratosphere. Thus winter Asian pollution may at have a smaller direct influence on the global atmosphere than it would if injected at other longitudes and seasons.

Browell, Edward V.↗

NASA NTRS1997

A Unified Directional Spectrum for Long and Short Wind-Driven Waves

Review of several recent ocean surface wave models finds that while comprehensive in many regards, these spectral models do not satisfy certain additional, but fundamental, criteria. We propose that these criteria include the ability to properly describe diverse fetch conditions and to provide agreement with in situ observations of Cox and Munk [1954] and Jiihne and Riemer [1990] and Hara et al. [1994] data in the high-wavenumber regime. Moreover, we find numerous analytically undesirable aspects such as discontinuities across wavenumber limits, nonphysical tuning or adjustment parameters, and noncentrosymmetric directional spreading functions. This paper describes a two-dimensional wavenumber spectrum valid over all wavenumbers and analytically amenable to usage in electromagnetic models. The two regime model is formulated based on the Joint North Sea Wave Project (JONSWAP) in the long-wave regime and on the work of Phillips [1985] and Kitaigorodskii [1973] at the high wavenumbers. The omnidirectional and wind-dependent spectrum is constructed to agree with past and recent observations including the criteria mentioned above. The key feature of this model is the similarity of description for the high- and low-wavenumber regimes; both forms are posed to stress that the air-sea interaction process of friction between wind and waves (i.e., generalized wave age, u/c) is occurring at all wavelengths simultaneously. This wave age parameterization is the unifying feature of the spectrum. The spectrum's directional spreading function is symmetric about the wind direction and has both wavenumber and wind speed dependence. A ratio method is described that enables comparison of this spreading function with previous noncentrosymmetric forms. Radar data are purposefully excluded from this spectral development. Finally, a test of the spectrum is made by deriving roughness length using the boundary layer model of Kitaigorodskii. Our inference of drag coefficient versus wind speed and wave age shows encouraging agreement with Humidity Exchange Over the Sea (HEXOS) campaign results.

Elfouhaily, T.↗

NASA NTRS2000

Implications of Simulation Conceptual Model Development for Simulation Management and Uncertainty Assessment

A simulation conceptual model is a simulation developers way of translating modeling requirements (i. e., what is to be represented by the simulation or its modification) into a detailed design framework (i. e., how it is to be done), from which the software, hardware, networks (in the case of distributed simulation), and systems/equipment that will make up the simulation can be built or modified. A conceptual model is the collection of information which describes a simulation developers concept about the simulation and its pieces. That information consists of assumptions, algorithms, characteristics, relationships, and data. Taken together, these describe how the simulation developer understands what is to be represented by the simulation (entities, actions, tasks, processes, interactions, etc.) and how that representation will satisfy the requirements to which the simulation responds. Thus the conceptual model is the basis for judgment about simulation fidelity and validity for any condition that is not specifically tested. The more perspicuous and precise the conceptual model, the more likely it is that the simulation development will both fully satisfy requirements and allow demonstration that the requirements are satisfied (i. e., validation). Methods used in simulation conceptual model development have significant implications for simulation management and for assessment of simulation uncertainty. This paper suggests how to develop and document a simulation conceptual model so that the simulation fidelity and validity can be most effectively determined. These ideas for conceptual model development apply to all simulation varieties. The paper relates these ideas to uncertainty assessments as they relate to simulation fidelity and validity. The paper also explores implications for simulation management from conceptual model development methods, especially relative to reuse of simulation components.

Pace, Dale K.↗

NASA NTRS2002

Determination of the Absolute Number of Cytokine mRNA Molecules within Individual Activated Human T Cells

A primary function of activated T cells is the expression and subsequent secretion of cytokines, which orchestrate the differentiation of other lymphocytes, modulate antigen presenting cell activity, and alter vascular endothelium to mediate an immune response. Since many features of immune regulation probably result from modest alterations of endogenous rates of multiple interacting processes, quantitative analysis of the frequency and specific activity of individual T cells is critically important. Using a coordinated set of quantitative methods, the absolute number of molecules of several key cytokine mRNA species in individual T cells has been determined. The frequency of human blood T cells activated in vitro by mitogens and recall protein antigens was determined by intracellular cytokine protein staining, in situ hybridization for cytokine mRNA, and by limiting dilution analysis for cytokine mRNA+ cells. The absolute number of mRNA molecules was simultaneously determined in both homogenates of the entire population of cells and in individual cells obtained by limiting dilution, using a quantitative, competitive RT-PCR assay. The absolute numbers of mRNA molecules in a population of cells divided by the frequency of individual positive cells, yielded essentially the same number of mRNA molecules per cell as direct analysis of individual cells by limiting dilution analysis. Mean numbers of mRNA per positive cell from both mitogen and antigen activated T cells, using these stimulation conditions, were 6000 for IL-2, 6300 for IFN-gamma, and 1600 for IL-4.

Karr, Laurel J.↗

NASA NTRS2002

Assessment of Spacecraft Systems Integration Using the Electric Propulsion Interactions Code (EPIC)

SAIC is currently developing the Electric Propulsion Interactions Code 'EPIC', an interactive computer tool that allows the construction of a 3-D spacecraft model, and the assessment of interactions between its subsystems and the plume from an electric thruster. EPIC unites different computer tools to address the complexity associated with the interaction processes. This paper describes the overall architecture and capability of EPIC including the physics and algorithms that comprise its various components. Results from selected modeling efforts of different spacecraft-thruster systems are also presented.

Mikellides, Ioannis G.↗

NASA NTRS2003

Applications of High Etendue Line-Profile Spectro-Polarimetry to the Study of the Atmospheric and Magnetospheric Environments of the Jovian Icy Moons

Electrodynamic effects play a significant, global role in the state and energization of the Earth's ionosphere/magnetosphere, but even more so on Jupiter, where the auroral energy input is four orders of magnitude greater than on Earth. The Jovian magnetosphere is distinguished from Earth's by its rapid rotation rate and contributions from satellite atmospheres and internal plasma sources. The electrodynamic effects of these factors have a key role in the state and energization of the ionosphere-corona- plasmasphere system of the planet and its interaction with Io and the icy satellites. Several large scale interacting processes determine conditions near the icy moons beginning with their tenuous atmospheres produced from sputtering, evaporative, and tectonic/volcanic sources, extending out to exospheres that merge with ions and neutrals in the Jovian magnetosphere. This dynamic environment is dependent on a complex network of magnetospheric currents that act on global scales. Field aligned currents connect the satellites and the middle and tail magnetospheric regions to the Jupiter's poles via flux tubes that produce as bright auroral and satellite footprint emissions in the upper atmosphere. This large scale transfer of mass, momentum, and energy (e.g. waves, currents) means that a combination of complementary diagnostics of the plasma, neutral, and and field network must be obtained near simultaneously to correctly interpret the results. This presentation discusses the applicability of UV spatial heterodyne spectroscopy (SHS) to the broad study of this system on scales from satellite surfaces to Jupiter's aurora and corona.

Harris, Walter M.↗

NASA NTRS2003

Future Facilities for Gamma-Ray Pulsar Studies

Pulsars seen at gamma-ray energies offer insight into particle acceleration to very high energies, along with information about the geometry and interaction processes in the magnetospheres of these rotating neutron stars. During the next decade, a number of new gamma-ray facilities will become available for pulsar studies. This brief review describes the motivation for gamma-ray pulsar studies, the opportunities for such studies, and some specific discussion of the capabilities of the Gamma-ray Large Area Space Telescope (GLAST) Large Area Telescope (LAT) for pulsar measurements.

Thompson, D. J.↗

NASA NTRS2003

Use of EOS Data in AWIPS for Weather Forecasting

Operational weather forecasting relies heavily on real time data and modeling products for forecast preparation and dissemination of significant weather information to the public. The synthesis of this information (observations and model products) by the meteorologist is facilitated by a decision support system to display and integrate the information in a useful fashion. For the NWS this system is called Advanced Weather Interactive Processing System (AWIPS). Over the last few years NASA has launched a series of new Earth Observation Satellites (EOS) for climate monitoring that include several instruments that provide high-resolution measurements of atmospheric and surface features important for weather forecasting and analysis. The key to the utilization of these unique new measurements by the NWS is the real time integration of the EOS data into the AWIPS system. This is currently being done in the Huntsville and Birmingham NWS Forecast Offices under the NASA Short-term Prediction Research and Transition (SPORT) Program. This paper describes the use of near real time MODIS and AIRS data in AWIPS to improve the detection of clouds, moisture variations, atmospheric stability, and thermal signatures that can lead to significant weather development. The paper and the conference presentation will focus on several examples where MODIS and AIRS data have made a positive impact on forecast accuracy. The results of an assessment of the utility of these products for weather forecast improvement made at the Huntsville NWS Forecast Office will be presented.

Jedlovec, Gary J.↗

NASA NTRS2000

A Quantitative Study of Oxygen as a Metabolic Regulator

An acute reduction in oxygen delivery to a tissue is associated with metabolic changes aimed at maintaining ATP homeostasis. However, given the complexity of the human bio-energetic system, it is difficult to determine quantitatively how cellular metabolic processes interact to maintain ATP homeostasis during stress (e.g., hypoxia, ischemia, and exercise). In particular, we are interested in determining mechanisms relating cellular oxygen concentration to observed metabolic responses at the cellular, tissue, organ, and whole body levels and in quantifying how changes in tissue oxygen availability affect the pathways of ATP synthesis and the metabolites that control these pathways. In this study; we extend a previously developed mathematical model of human bioenergetics, to provide a physicochemical framework that permits quantitative understanding of oxygen as a metabolic regulator. Specifically, the enhancement - sensitivity analysis - permits studying the effects of variations in tissue oxygenation and parameters controlling cellular respiration on glycolysis, lactate production, and pyruvate oxidation. The analysis can distinguish between parameters that must be determined accurately and those that require less precision, based on their effects on model predictions. This capability may prove to be important in optimizing experimental design, thus reducing use of animals.

Radhakrishnan, Krishnan↗

NASA NTRS1999

A Quantitative Study of Oxygen as a Metabolic Regulator

An acute reduction in oxygen (O2) delivery to a tissue is generally associated with a decrease in phosphocreatine, increases in ADP, NADH/NAD, and inorganic phosphate, increased rates of glycolysis and lactate production, and reduced rates of pyruvate and fatty acid oxidation. However, given the complexity of the human bioenergetic system and its components, it is difficult to determine quantitatively how cellular metabolic processes interact to maintain ATP homeostasis during stress (e.g., hypoxia, ischemia, and exercise). Of special interest is the determination of mechanisms relating tissue oxygenation to observed metabolic responses at the tissue, organ, and whole body levels and the quantification of how changes in tissue O2 availability affect the pathways of ATP synthesis and the metabolites that control these pathways. In this study, we extend a previously developed mathematical model of human bioenergetics to provide a physicochemical framework that permits quantitative understanding of O2 as a metabolic regulator. Specifically, the enhancement permits studying the effects of variations in tissue oxygenation and in parameters controlling the rate of cellular respiration on glycolysis, lactate production, and pyruvate oxidation. The whole body is described as a bioenergetic system consisting of metabolically distinct tissue/organ subsystems that exchange materials with the blood. In order to study the dynamic response of each subsystem to stimuli, we solve the ordinary differential equations describing the temporal evolution of metabolite levels, given the initial concentrations. The solver used in the present study is the packaged code LSODE, as implemented in the NASA Lewis kinetics and sensitivity analysis code, LSENS. A major advantage of LSENS is the efficient procedures supporting systematic sensitivity analysis, which provides the basic methods for studying parameter sensitivities (i.e., changes in model behavior due to parameter variation). Sensitivity analysis establishes relationships between model predictions and problem parameters (i.e., initial concentrations, rate coefficients, etc). It helps determine the effects of uncertainties or changes in these input parameters on the predictions, which ultimately are compared with experimental observations in order to validate the model. Sensitivity analysis can identify parameters that must be determined accurately because of their large effect on the model predictions and parameters that need not be known with great precision because they have little or no effect on the solution. This capability may prove to be important in optimizing the design of experiments, thereby reducing the use of animals. This approach can be applied to study the metabolic effects of reduced oxygen delivery to cardiac muscle due to local myocardial ischemia and the effects of acute hypoxia on brain metabolism. Other important applications of sensitivity analysis include identification of quantitatively relevant pathways and biochemical species within an overall mechanism, when examining the effects of a genetic anomaly or pathological state on energetic system components and whole system behavior.

Radhakrishnan, Krishnan↗

NASA NTRS2003

A quantitative study of oxygen as a metabolic regulator

An acute reduction in oxygen delivery to a tissue is associated with metabolic changes aimed at maintaining ATP homeostasis. However, given the complexity of the human bioenergetic system, it is difficult to determine quantitatively how cellular metabolic processes interact to maintain ATP homeostasis during stress (e.g., hypoxia, ischemia, and exercise). In particular, we are interested in determining mechanisms relating cellular oxygen concentration to observed metabolic responses at the cellular, tissue, organ, and whole body levels and in quantifying how changes in tissue oxygen availability affect the pathways of ATP synthesis and the metabolites that control these pathways. In this study, we extend a previously developed mathematical model of human bioenergetics, to provide a physicochemical framework that permits quantitative understanding of oxygen as a metabolic regulator. Specifically, the enhancement--sensitivity analysis--permits studying the effects of variations in tissue oxygenation and parameters controlling cellular respiration on glycolysis, lactate production, and pyruvate oxidation. The analysis can distinguish between parameters that must be determined accurately and those that require less precision, based on their effects on model predictions. This capability may prove to be important in optimizing experimental design, thus reducing use of animals.

Non-programmatic↗

NASA NTRS1992

CELSS system control: issues, methods, and directions

In the general control perspective, the CELSS concept implies a very complex system and presents challenges at every level. These challenges are generated by: (1) the prospect that the system will be inherently unstable, (2) the prospective difficulty of establishing an adequate mathematical model of the system for the purpose of control law synthesis (dimensionality is high, and the dynamics and interactive processes of some of the subsystems are not understood well), (3) assuring control law robustness (assuring that the resulting control law(s) will be effective over the domain of the specified uncertainties), (4) hardware realization of the control law, (5) hardware system robustness ("fault tolerance") and (6) achieving the logistics of the automation (or "management") aspects of the problem. A suggested organization of the problem, a sketch of the issues related to perceived difficulties, a commentary/evaluation of the issues, a review of methods available to address the issues, and a suggested strategy to address the broad CELSS systems control problem are presented.

NASA Center ARC↗

NASA NTRS2004

A Computational and Experimental Investigation of a Delta Wing with Vertical Tails

The flow over an aspect ratio 1 delta wing with twin vertical tails is studied in a combined computational and experimental investigation. This research is conducted in an effort to understand the vortex and fin interaction process. The computational algorithm used solves both the thin-layer Navier-Stokes and the inviscid Euler equations and utilizes a chimera grid-overlapping technique. The results are compared with data obtained from a detailed experimental investigation. The laminar case presented is for an angle of attack of 20 and a Reynolds number of 500; 000. Good agreement is observed for the physics of the flow field, as evidenced by comparisons of computational pressure contours with experimental flow-visualization images, as well as by comparisons of vortex-core trajectories. While comparisons of the vorticity magnitudes indicate that the computations underpredict the magnitude in the wing primary-vortex-core region, grid embedding improves the computational prediction.

Krist. Sherrie L.↗

NASA NTRS1999

Boronate affinity adsorption of RNA: possible role of conformational changes

Batch equilibrium adsorption isotherm determination is used to characterize the adsorption of mixed yeast RNA on agarose-immobilized m-aminophenylboronic acid. It is shown that the affinity-enhancing influence of divalent cations depends strongly on the precise nature of the cation used, with barium being far more effective than the conventionally-used magnesium. This adsorption-promoting influence of barium is suggested to arise primarily from ionic influences on the structure and rigidity of the RNA molecule, as the adsorption of ribose-based small molecules is not similarly affected. The substitution of barium for the standard magnesium counterion does not greatly promote the adsorption of DNA, implying that the effect is specific to RNA and may be useful in boronate-based RNA separations. RNA adsorption isotherms exhibit sharp transitions as functions of temperature, and these transitions occur at different temperatures with Mg2+ and with Ba2+. Adsorption affinity and capacity were found to increase markedly at lower temperatures, suggestive of an enthalpically favored interaction process. The stoichiometric displacement parameter, Z, in Ba2+ buffer is three times the value in Mg2+ buffer, and is close to unity.

NASA Discipline Environmental Health↗

NASA NTRS2004

MODIS Data in AWIPS: A Precursor of NPOESS and GOES-R Capabilities

MODIS data from NASA's Terra and Aqua satellites are being sent to several NWS Forecast Offices in real time to assist in the preparation of short-term weather forecasts. The MODIS imagery, in channels similar to those of the planned GOES-R instrument, is reformatted, sectorized, and ingested directly in Advanced Weather Interactive Processing System (AWIPS). A number of products derived from the imagery are available in near real-time as well. This transition activity, from research to operations, serves to prepare forecasters for the next generation satellite observing capabilities through real-time, hands on applications to their forecast problems. The presentation will provide examples of this transition activity and a preliminary assessment on the utility of several of the MODIS products for improving short-term forecasts.

Jedlovec, Gary↗