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At least 325 records · Page 18

A continuous physiological data collector

COP-DAC system utilizes oxygen and carbon dioxide analyzers, gas-flow meter, gas breathe-through system, analog computer, and data storage system to provide actual rather than average measurements of physiological and metabolic functions.

Bush, J. C.↗

Development of mathematical models of environmental physiology

Selected articles concerned with mathematical or simulation models of human thermoregulation are presented. The articles presented include: (1) development and use of simulation models in medicine, (2) model of cardio-vascular adjustments during exercise, (3) effective temperature scale based on simple model of human physiological regulatory response, (4) behavioral approach to thermoregulatory set point during exercise, and (5) importance of skin temperature in sweat regulation.

Stolwijk, J. A. J.↗

Cardiocirculatory responses to exercise - Physiologic study by noninvasive techniques.

The changes from rest to exercise were determined for certain phases of the cardiac cycle in ten healthy male subjects who underwent submaximal, physiologically paced bicycle ergometry. ECGs, phonocardiograms, and carotid pu lse tracings were recorded. The preejection period and isovolumic contraction time decreased with exercise. Changes in left ventricular ejection time appeared to depend on the severity or the duration of stress. Pulse transmission time did not change significantly. The data obtained in the study and comparison of these results to those obtained by invasive methods indicate that noninvasive techniques, when used in the manner suggested, are appropriate means for detecting a variety of cardiocirculatory changes during exercise.

Pigott, V. M.↗

Biochemical and physiological consequences of the Apollo flight diet.

Six male subjects subsisting on a typical Apollo flight diet for five consecutive days were evaluated for changes in biochemical and physiological status. Laboratory examinations failed to demonstrate any significant changes of the kind previously attributed to weightlessness, such as in serum electrolytes, endocrine values, body fluid, or hematologic parameters.

Hander, E. W.↗

Physiological control - A physical view: Life and the biochemical oscillator.

The history and progress of physical interpretations of physiological control, viewing life as a biochemical oscillator, are surveyed. Special attention is given to the author's studies (1964, 1965, 1968 and 1969) and to studies of Katchalsky (1969) who demonstrated a 1,000-A scale which may provide a basis for a biochemical oscillator.

Iberall, A. S.↗

Circadian rhythms of visual accommodation responses and physiological correlations.

Use of a recently developed servocontrolled infrared optometer to continuously record the state of monocular focus while subjects viewed a visual target for which the stimulus to focus was systematically varied. Calculated parameters form recorded data - e.g., speeds of accommodation to approaching and receding targets, magnitude of accommodation to step changes in target distance, and amplitude and phase lag of response to sinusoidally varying stimuli were submitted to periodicity analyses. Ear canal temperature (ECT) and heart rate (HR) rhythms were also recorded for physiological correlation with accommodation rhythms. HR demonstrated a 24-hr rhythm, but ECT data did not.

Murphy, M. R.↗

The foundations of space biology and medicine. Volume 2: Ecological and physiological bases of space biology and medicine. Part 3: Effect on the organism of dynamic flight factors. Chapter 1: Principles of gravitational biology

The physical principles of gravitation are discussed, such as gravitational and intertial forces, weight and mass, weightlessness, size and scale effects, scale limits of gravitational effects, and gravity as a biogenic factor. The behavior of the accelerative force gravitation, is described. This law proposes and quantifies the mutual gravitational attraction existing between all bodies of matter, the force being proportional to the product of masses, and inversely related to the square of the distance separating them. Gravity orientation, chronic acceleration, and hematology are examined. Systematic responses, such as circulation and renal functions, are also considered, along with animal response to a decreased acceleration field and physiology of hyper- and hypodynamic fields.

Smith, A. H.↗

Study of physiological and behavioral response to transitions between rotating and nonrotating environments

Future manned space missions may require transition between artificial gravity and weightlessness environments. The frequency and rate of such transition will influence the psychophysiological responses of man. Abrupt transfers are examined between such rotating and nonrotating environments to determine the physiological and behavioral responses of man. Five subjects were tested using rates of rotation up to 5 rpm.

Brady, J. F.↗

Specialized physiological studies in support of manned space flight

The areas of physiological research reported include: (1) evaluation of the single-breath method for determining cardiac output, (2) optimum protocol for the assessment of cardio-pulmonary competence, (3) body fluids and electrolytes under conditions of single and combined stress, (4) re-evaluation of the open-circuit method for measuring metabolic rate with regard to the alleged metabolic production of gaseous nitrogen, and (5) the use of the forced-oscillation method to determine total respiratory conductance in healthy subjects and pulmonary patients.

Luft, U. C.↗

Physiology of chimpanzees in orbit. Part 2: Interface document

Interface requirements are presented for the design and development of an earth orbiting experiment to be known as POCO, Physiology of Chimpanzees in Orbit. The POCO experiment may be designed to operate within an orbiting space station (provided artificial gravity measures are not employed), a Saturn 4-B workshop, an Apollo command module or service module, a Saturn-1B spacecraft LM adapter, or aboard one of the presently conceived appendages connected by an umbilical to a space station. This document sets forth the experiment definition and requirements and describes the hardware under development to accomplish these objectives.

Firstenberg, A.↗

Method for analyses of cyclic physiological data that are nonstationary in time.

The proposed method of studying biologic rhythms permits the biologist to view physiological data dynamically without assuming that the data are stationary in time. Vector representation of data points is employed, and the summation of the vectors (train of vectors) produces a summation dial that is able to detect dynamic changes in the time of the peak as well as random walks (arrhythmia).

Winget, C. M.↗

Programmable physiological infusion

A programmable physiological infusion device and method are provided wherein a program source, such as a paper tape, is used to actuate an infusion pump in accordance with a desired program. The system is particularly applicable for dispensing calcium in a variety of waveforms.

Howard, W. H.↗

Research on gravitational physiology

The topic of gravitational plant physiology was studied through aspects of plant development (in ARABIDOPSIS) and of behavior (in HELIANTHUS) as these were affected by altered g experience. The effect of increased g levels on stem polarity (in COLEUS) was also examined.

Brown, A. H.↗