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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 325 records · Page 18
All sourcesNASA NTRSDOE OSTI
NASA NTRSDate not supplied

Differential Gene Expression in A Cross-Feeding Two-Species Model Microbial Community Under Simulated Microgravity and Deep-Space Radiation

A long-term goal of space biology is to understand interspecies microbial interactions in space. Presently, little is known about the combined effect of microgravity and ionizing radiation on bacterial community response when species are interdependent through exchange of metabolites in fluid medium (cross-feeding). Microgravity is expected to slow interspecies mass transfer and growth in cross-feeding communities in the low-shear, diffusion-limited environment, while ionizing radiation may influence stress response to direct (DNA damage) and indirect damage (ROS). Using a well-understood, two-species (Escherichia coli and Salmonella enterica) microbial community engineered to be a model for studying cross-feeding, we simulated galactic cosmic rays (GCRsim) and microgravity to test the hypothesis: exposure to ionizing radiation causes cell damage or stress, altering transcriptomic community responses in metabolically interdependent cells, which is exacerbated by microgravity. We expect to see differential gene expression between cross-feeding and non-cross-feeding communities. We measured GCRsim effects on growth and gene expression in well-mixed versus simulated-microgravity conditions and in cross-feeding and non-cross-feeding medium. Microbial cultures were inoculated into liquid medium in rotating wall vessels (RWV) with different rotation rates: 5 RPM (simulated microgravity) and 50 RPM (well-mixed). The E. coli-S. enterica consortium, under simulated microgravity, were exposed to 500 mGy of Simplified 5-ion Galactic Cosmic Ray Simulation for 2 hours at Brookhaven National Lab. We harvested samples 40 minutes after irradiation for extraction and sequencing (NASA GeneLab). Here we present the differential gene expression analysis results, which reveal altered transcriptomic community responses, even where growth rate differences are not observed. Gene expression of these actively metabolizing microbial communities in GCRsim may illuminate molecular mechanisms of microbial interactions in space. Understanding how microbial community gene expression, metabolism, and other cellular processes are influenced by spaceflight stressors can inform the use of microbes in human life support for low Earth orbit missions and beyond.

microgravity↗
NASA NTRS1973

Investigation into the propagation of Omega very low frequency signals and techniques for improvement of navigation accuracy including differential and composite omega

An analysis of Very Low Frequency propagation in the atmosphere in the 10-14 kHz range leads to a discussion of some of the more significant causes of phase perturbation. The method of generating sky-wave corrections to predict the Omega phase is discussed. Composite Omega is considered as a means of lane identification and of reducing Omega navigation error. A simple technique for generating trapezoidal model (T-model) phase prediction is presented and compared with the Navy predictions and actual phase measurements. The T-model prediction analysis illustrates the ability to account for the major phase shift created by the diurnal effects on the lower ionosphere. An analysis of the Navy sky-wave correction table is used to provide information about spatial and temporal correlation of phase correction relative to the differential mode of operation.

Source record↗
NASA NTRS1991

Combustion kinetics and sensitivity analysis computations

The stiff ordinary differential equation solution methods more commonly used for chemical kinetics problems are examined, and the efficiency and accuracy of several of the methods are compared by applying them to two combustion kinetics problems. The local sensitivity analysis methods developed to date are outlined, and their advantages and difficulties are briefly discussed. Examples are used to make comparisons among the different techniques.

Radhakrishnan, K.↗
NASA NTRS1991

An introduction to autonomous control systems

The functions, characteristics, and benefits of autonomous control are outlined. An autonomous control functional architecture for future space vehicles that incorporates the concepts and characteristics described is presented. The controller is hierarchical, with an execution level (the lowest level), coordination level (middle level), and management and organization level (highest level). The general characteristics of the overall architecture, including those of the three levels, are explained, and an example to illustrate their functions is given. Mathematical models for autonomous systems, including 'logical' discrete event system models, are discussed. An approach to the quantitative, systematic modeling, analysis, and design of autonomous controllers is also discussed. It is a hybrid approach since it uses conventional analysis techniques based on difference and differential equations and new techniques for the analysis of the systems described with a symbolic formalism such as finite automata. Some recent results from the areas of planning and expert systems, machine learning, artificial neural networks, and the area restructurable controls are briefly outlined.

Antsaklis, Panos J.↗
NASA NTRS1981

An analytic solution to the classical two-body problem with drag

The two body problem was analyzed with a specific drag model. The model treats drag as a force proportional to the vector velocity and inversely proportional to the distance to the center of attraction. The solution is expressed in terms of known functions and is of a simple and compact form. The time of flight is expressed as a quadrature in the true anomaly. The results are: (1) development of a vector differential equation which allows analysis of an infinite number of gravitational and drag models; and (2) obtaining the solution of a linear differential equation using the inverse method of laplace transforms.

Mittleman, D.↗
NASA NTRS1990

Stability analysis of multigrid acceleration methods for the solution of partial differential equations

A calculation is made of the stability of various relaxation schemes for the numerical solution of partial differential equations. A multigrid acceleration method is introduced, and its effects on stability are explored. A detailed stability analysis of a simple case is carried out and verified by numerical experiment. It is shown that the use of multigrids can speed convergence by several orders of magnitude without adversely affecting stability.

Fay, John F.↗
NASA NTRS1974

Fluid dynamics and kinematics of molten metals in the low-gravity environment of Skylab

The response of molten metals to mechanical and thermal driving forces in nominal and microgravity is analyzed both theoretically and experimentally. The magnitude and transient behavior of internal fluid circulations, surface deformations, and globule trajectories and their effects on solidification in the Skylab electron beam sphere forming and metals melting experiments are determined. The theoretical approach consists of dimensional analysis of the governing differential equations. Experimental aspects include evaluation of specimens from terrestrial, KC-135 research aircraft, and actual Skylab tests and analysis of high speed movies taken during the melting processes. Several gravity variations and gravity independent results were successfully predicted based on expected differences and similarities in fluid dynamics.

Bourgeois, S. V.↗
NASA NTRS1986

Assesment of dial data collection and analysis techniques

The key issues in all areas of Differential Absorption Lidar (DIAL) data collection and analysis techniques were examined. This included consideration of the practical and theoretical limitations of DIAL and the range of possible DIAL measurements.

Browell, E. V.↗
NASA NTRS1986

Radiative transfer in a sphere illuminated by a parallel beam - An integral equation approach

The problem of multiple scattering of nonpolarized light in a planetary body of arbitrary shape illuminated by a parallel beam is formulated using the integral equation approach. There exists a simple functional whose stationarity condition is equivalent to solving the equation of radiative transfer and whose value at the stationary point is proportional to the differential cross section. The analysis reveals a direct relation between the microscopic symmetry of the phase function for each scattering event and the macroscopic symmetry of the differential cross section for the entire planetary body, and the interconnection of these symmetry relations and the variational principle. The case of a homogeneous sphere containing isotropic scatterers is investigated in detail. It is shown that the solution can be expanded in a multipole series such that the general spherical problem is reduced to solving a set of decoupled integral equations in one dimension. Computations have been performed for a range of parameters of interest, and illustrative examples of applications to planetary problems as provided.

Shia, R.-L.↗
NASA NTRS1978

An extension of A-stability to alternating direction implicit methods

An alternating direction implicit (ADI) scheme was constructed by the method of approximate factorization. An A-stable linear multistep method (LMM) was used to integrate a model two-dimensional hyperbolic-parabolic partial differential equation. Sufficient conditions for the A-stability of the LMM were determined by applying the theory of positive real functions to reduce the stability analysis of the partial differential equations to a simple algebraic test. A linear test equation for partial differential equations is defined and then used to analyze the stability of approximate factorization schemes. An ADI method for the three-dimensional heat equation is also presented.

Warming, R. F.↗
NASA NTRS1976

Studies of aircraft differential maneuvering. Report 75-27: Calculating of differential-turning barrier surfaces. Report 75-26: A user's guide to the aircraft energy-turn and tandem-motion computer programs. Report 75-7: A user's guide to the aircraft energy-turn hodograph program

The numerical analysis of composite differential-turn trajectory pairs was studied for 'fast-evader' and 'neutral-evader' attitude dynamics idealization for attack aircraft. Transversality and generalized corner conditions are examined and the joining of trajectory segments discussed. A criterion is given for the screening of 'tandem-motion' trajectory segments. Main focus is upon the computation of barrier surfaces. Fortunately, from a computational viewpoint, the trajectory pairs defining these surfaces need not be calculated completely, the final subarc of multiple-subarc pairs not being required. Some calculations for pairs of example aircraft are presented. A computer program used to perform the calculations is included.

Kelley, H. J.↗
NASA NTRS1978

Use of asymptotic methods in vibration analysis

The derivation of dynamic differential equations, suitable for studying the vibrations of rotating, curved, slender structures was examined, and the Hamiltonian procedure was advocated for this purpose. Various reductions of the full system are displayed, which govern the vibrating troposkien when various order of magnitude restrictions are placed on important parameters. Possible advantages of the WKB asymptotic method for solving these classes of problems are discussed. A special case of this method is used illustratively to calculate eigenvalues and eigenfunctions for a flat turbine blade with small flexural stiffness.

Ashley, H.↗