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LENR Products: Lattice Confinement Fusion (LCF), Fission, or Both?

Lattice Confinement Fusion (LCF) or Low Energy Nuclear Reactions (LENR) generate heat from the high energy products they produce. Conventionally, d-d fusion reactions may produce either 2.45 MeV neutrons, 3 MeV protons, or high energy gammas. Generally, fission will give 5-10x the excess energy of fusion. However, aneutronic “cold fusion” would provide 24 MeV/reaction, D(d,γ) 4 He, where the gamma is suppressed. In a series of pressurized gas cycling experiments with a palladium silver (75 wt.% Pd and 25 wt.% Ag or Pd25Ag) alloy [1], samples cycled with deuterium showed excess heat via unexplained temperature rises. Post-test analysis of the Pd25Ag samples using a Scanning Electron Microscope (SEM/EDX) showed several molten features containing anomalous elements other than Pd and Ag. Researchers such as Liu et al [2] have also observed transmutations under similar conditions. These molten areas and anomalous elements suggest Pd fission. This nuclear process has been referred to as nuclear disintegration. Either nuclear fission or disintegration may result in neutron rich fragments. The fragments would rapidly beta decay to shorter lived daughters until they reach stability. We’ve observed evidence of both fusion and fission products [3]. Figure 1 shows neutron spectroscopy showing fusion and boosted neutron energies in bremsstrahlung-initiated fusion of TiD2. Figure 2 shows possible fission products from D2 gas cycled Pd25Ag alloy. Alternatively, Oppenheimer-Phillips stripping reactions, enhanced by electron screening [4] may also occur. In this case, the 8.6 MeV binding energy per Pd or Ag minus the 2.2 MeV deuteron binding energy leaves 6.4 MeV distributed between the reaction products. The energy is shared inversely proportional to the masses of the stripped off nucleon, p or n, and the new target nucleus.

Theresa L. Benyo↗

The global distribution of giant radiating dike swarms on Venus: Implications for the global stress state

Magellan radar data of Venus reveal 163 large radial lineament systems composed of graben, fissure, and fracture elements. On the basis of their structure, plan view geometry, and volcanic associations, at least 72% are interpreted to have formed primarily through subsurface dike swarm emplacement, the remainder through uplift or a combination of these two mechanisms. The population of swarms is used to determine regional and global stress orientation. The stress configuration recorded from 330-210 deg E (Aphrodite Terra) is best explained by isostatic compensation of existing long wavelength topography or coupling between mantle flow and the lithosphere. The rest are correlated with concentrations of rifting and volcanism in the Beta-Atla-Themis region. The global stress field on Venus is different than that of Earth, where plate boundary forces dominate.

Grosfils, Eric B.↗

Creating unstable velocity-space distributions with barium injections

Ion velocity-space distributions resulting from barium injections from orbiting spacecraft and shaped charges are discussed. Active experiments confirm that anomalous ionization processes may operate, but photoionization accounts for the production of the bulk of the barium ions. Pitch-angle diffusion and/or velocity-space diffusion may occur, but observations of barium ions moving upwards against gravity suggests that the ions retain a significant enough fraction of their initial perpendicular velocity to provide a mirror force. The barium ion plasmas should have a range of Alfven Mach numbers and plasma betas. Because the initial conditions can be predicted these active experiments should permit testing plasma instability hypotheses.

Pongratz, M. B.↗

Planetary optical and infrared imaging

The purpose of this investigation is to obtain and analyze high spatial resolution charge coupled device (CCD) coronagraphic images of extra-solar planetary material and solar system objects. These data will provide information on the distribution of planetary and proto-planetary material around nearby stars leading to a better understanding of the origin and evolution of the solar system. Imaging within our solar system will provide information on the current cloud configurations on the outer planets, search for new objects around the outer planets, and provide direct support for Voyager, Galileo, and CRAF by imaging material around asteroids and clouds on Neptune. Over the last year this program acquired multispectral and polarization images of the disk of material around the nearby star Beta Pictoris. This material is believed to be associated with the formation of planets and provides a first look at a planetary system much younger than our own. Preliminary color and polarization data suggest that the material is very low albedo and similar to dark outer solar system carbon rich material. A coronagraphic search for other systems is underway and has already examined over 100 nearby stars. Coronagraphic imaging provided the first clear look at the rings of Uranus and albedo limits for the ring arcs around Neptune.

Terrile, R. J.↗

The SEEDS Direct Imaging Survey for Planets and Scattered Dust Emission in Debris Disk Systems

Debris disks around young main-sequence stars often have gaps and cavities which for a long time have been interpreted as possibly being caused by planets. In recent years, several giant planet discoveries have been made in systems hosting disks of precisely this nature, further implying that interactions with planets could be a common cause of such disk structures. As part of the SEEDS high-contrast imaging survey, we are surveying a population of debris disk-hosting stars with gaps and cavities implied by their spectral energy distributions, in order to attempt to spatially resolve the disk as well as to detect any planets that may be responsible for the disk structure. Here we report on intermediate results from this survey. Five debris disks have been spatially resolved, and a number of faint point sources have been discovered, most of which have been tested for common proper motion, which in each case has excluded physical companionship with the target stars. From the detection limits of the 50 targets that have been observed, we find that beta Pic b-like planets (approximately 10M(sub jup) planets around G-A-type stars) near the gap edges are less frequent than 15-30%, implying that if giant planets are the dominant cause of these wide (27 AU on average) gaps, they are generally less massive than beta Pic b.

high-contrast imaging↗

LENR Products: Lattice Confinement Fusion (LCF), Fission, or Both?

Lattice Confinement Fusion (LCF) or Low Energy Nuclear Reactions (LENR) generate heat from the high energy products they produce. Conventionally, d-d fusion reactions may produce either 2.45 MeV neutrons, 3 MeV protons, or high energy gammas. Generally, fission will give 5-10x the excess energy of fusion. However, aneutronic “cold fusion” would provide 24 MeV/reaction, D(d,γ) 4 He, where the gamma is suppressed. In a series of pressurized gas cycling experiments with a palladium silver (75 wt.% Pd and 25 wt.% Ag or Pd25Ag) alloy [1], samples cycled with deuterium showed excess heat via unexplained temperature rises. Post-test analysis of the Pd25Ag samples using a Scanning Electron Microscope (SEM/EDX) showed several molten features containing anomalous elements other than Pd and Ag. Researchers such as Liu et al [2] have also observed transmutations under similar conditions. These molten areas and anomalous elements suggest Pd fission. This nuclear process has been referred to as nuclear disintegration. Either nuclear fission or disintegration may result in neutron rich fragments. The fragments would rapidly beta decay to shorter lived daughters until they reach stability. We’ve observed evidence of both fusion and fission products [3]. Figure 1 shows neutron spectroscopy showing fusion and boosted neutron energies in bremsstrahlung-initiated fusion of TiD2. Figure 2 shows possible fission products from D 2 gas cycled Pd25Ag alloy. Alternatively, Oppenheimer-Phillips stripping reactions, enhanced by electron screening [4] may also occur. In this case, the 8.6 MeV binding energy per Pd or Ag minus the 2.2 MeV deuteron binding energy leaves 6.4 MeV distributed between the reaction products. The energy is shared inversely proportional to the masses of the stripped off nucleon, p or n, and the new target nucleus.

Theresa L. Benyo↗

Everything you ever wanted to know about the ultraviolet spectra of star-forming galaxies but were afraid to ask

We present ultraviolet spectra of 143 star-forming galaxies of different morphological types and activity classes including S0, Sa, Sb, Sc, Sd, irregular, starburst, blue compact, blue compact dwarf, Liner, and Seyfert 2 galaxies. These IUE spectra cover the wavelength range from 1200 to 3200 A and are taken in a large aperture (10 x 20 inch). The ultraviolet spectral energy distributions are shown for a subset of the galaxies, ordered by spectral index, and separated by type for normal galaxies, Liners, starburst galaxies, blue compact (BCG) and blue compact dwarf (BCDG) galaxies, and Seyfert 2 galaxies. The ultraviolet spectra of Liners are, for the most part, indistinguishable from the spectra of normal galaxies. Starburst galaxies have a large range of ultraviolet slope, from blue to red. The star-forming galaxies which are the bluest in the optical (BCG and BCDG), also have the 'bluest' average ultraviolet slope of beta = -1.75 +/- 0.63. Seyfert 2 galaxies are the only galaxies in the sample that consistently have detectable UV emission lines.

Kinney, A. L.↗

The distribution of dark matter in the A2256 cluster

Using spatially resolved X-ray spectroscopy, it was determined that the X-ray emitting gas in the rich cluster A2256 is nearly isothermal to a radius of at least 0.76/h Mpc, or about three core radii. These data can be used to measure the distribution of the dark matter in the cluster. It was found that the total mass interior to 0.76/h Mpc and 1.5/h Mpc is (0.5 +/- 0.1 and 1.0 +/- 0.5) x 10(exp 15)/h of the solar mass respectively where the errors encompass the full range allowed by all models used. Thus, the mass appropriate to the region where spectral information was obtained is well determined, but the uncertainties become large upon extrapolating beyond that region. It is shown that the galaxy orbits are midly anisotropic which may cause the beta discrepancy in this cluster.

Henry, J. Patrick↗

Influence of Coronal Abundance Variations

The PI of this project was Jeff Scargle of NASA/Ames. Co-I's were Alma Connors of Eureka Scientific/Wellesley, and myself. Part of the work was subcontracted to Eureka Scientific via SAO, with Vinay Kashyap as PI. This project was originally assigned grant number NCC2-1206, and was later changed to NCC2-1350 for administrative reasons. The goal of the project was to obtain, derive, and develop statistical and data analysis tools that would be of use in the analyses of high-resolution, high-sensitivity data that are becoming available with new instruments. This is envisioned as a cross-disciplinary effort with a number of "collaborators" including some at SA0 (Aneta Siemiginowska, Peter Freeman) and at the Harvard Statistics department (David van Dyk, Rostislav Protassov, Xiao-li Meng, Epaminondas Sourlas, et al). We have developed a new tool to reliably measure the metallicities of thermal plasma. It is unfeasible to obtain high-resolution grating spectra for most stars, and one must make the best possible determination based on lower-resolution, CCD-type spectra. It has been noticed that most analyses of such spectra have resulted in measured metallicities that were significantly lower than when compared with analyses of high- resolution grating data where available (see, e.g., Brickhouse et al., 2000, ApJ 530,387). Such results have led to the proposal of the existence of so-called Metal Abundance Deficient, or "MAD" stars (e.g., Drake, J.J., 1996, Cool Stars 9, ASP Conf.Ser. 109, 203). We however find that much of these analyses may be systematically underestimating the metallicities, and using a newly developed method to correctly treat the low-counts regime at the high-energy tail of the stellar spectra (van Dyk et al. 2001, ApJ 548,224), have found that the metallicities of these stars are generally comparable to their photospheric values. The results were reported at the AAS (Sourlas, Yu, van Dyk, Kashyap, and Drake, 2000, BAAS 196, v32, #54.02), and at the conference on Statistical Challenges in Modem Astronomy (Sourlas, van Dyk, Kashyap, Drake, and Pease, 2003, SCMA 111, Eds. E.D.Feigelson, G.J.Babu, New York:Springer, p489-490). We also described the limitations of one of the most egregiously misused and misapplied statistical tests in astrophysical literature, the F-test for verifying model components (Protassov, van Dyk, Connors, Kashyap, and Siemiginowska, 2002, ApJ, 571,545). Indeed, a search through the ApJ archives turned up 170 papers in the 5 previous years that used the F-test explicitly in some form or the other, and with the vast majority of them not using it correctly! Indeed, looking at just 4 issues of the ApJ in 2001, we found 13 instances of its use, of which nine were demonstrably incorrect. Clearly, it is difficult to understate the importance of this issue. We also worked on speeding up Bayes Blocks and Sparse Bayes Blocks algorithms to make them more tractable for large searches. We also supported staistics students and postdocs in both explicit physics- model-based (spectra with tens of thousands of atomic lines) and "model-free" -- i.e. non-parametric or semi-parametric -- algorithms. Work on using more of the latter is just beginning; while using multi-scale methods for Poisson imaging has come to hition. In fact, "An Image Restoration Technique with Error Estimates", by D. Esch, A. Connors, M. Karovska, and D. van Dyk, was published by ApJ (Esch et a1.2004, ApJ, 610, 1213). The code has been delivered to M. Karovska for CXC; and is available for beta-testing upon request. The other large project we worked on was on the self-consistent modeling of logN-logs curves in the Poisson limit. logN-logs curves are a fundamental tool in the study of source populations, luminosity functions, and cosmological parameters. However, their determination is hampered by statistical effects such as the Eddington bias, incompleteness due to detection efficiency, faint source flux fluctuations, etc. We have develed a new and powerful method using the full Poisson machinery that allows us to model the logN-logs distribution of X-ray sources in a self-consistent manner. Because we properly account for all the above statistical effects, our modeling is valid over the full range of the data, and not just for strong sources, as is normally done. Using a Bayesian approach and modeling the fluxes with known functional forms such as simple or broken power-laws, and conditioning the expected photon counts on the fluxes, the background contamination, effective area, detector vignetting, and detection probability, we can delve deeply into the low counts regime and extend the usefulness of medium sensitivity surveys such as ChAMP by orders of magnitude. The built-in flexibility of the algorithm also allows a simultaneous analysis of multiple datasets. We have applied this analysis to a set a Chandra observations (Sourlas, Kashyap, Zezas, van Dyk, 2004, HEAD #8, #16.32)

Scargle, Jeffrey D.↗

Spectroscopic Diagnostics and an Arc Jet Heated Air Plasma

Spectral radiation measurements were made in the range of 200 to 900 nm across a section of the plenum of an arc jet wind tunnel using a series of optical fibers. The spectra contained line radiation from Oxygen and Nitrogen atoms and molecular radiation from N2(+), N2, and NO. Abel inversion technique is used to obtain radial distribution of the spectra. The analysis yielded radial profiles of the electronic excitation, vibrational and rotational temperatures of the flow field. Spectral fitting yielded branching ratios for different vibrational and rotational bands. Relatively mild flow conditions, i.e. enthalpy and mass flow rate, were used for prolonged measurements of up to and over two hours to establish the best experimental methods of temperature determinations. Signal to noise was improved by at least an order of magnitude enabling the molecular vibrational band heads of N2(+) (first negative system), N2 (second positive system), and NO (beta, gamma, delta, and epsilon systems) to be resolved in the lower ultraviolet wavelength regions. The increased signal to noise ratio also enabled partial resolution of the rotational lines of N2(+) and N2 in certain regions of minimal overlap. Comparison of the spectra with theoretical models such as the NEQAIR2 code are presented and show potential for fitting the spectra when reliable calibration is performed for the complete wavelength range.

Mack, Larry Howard, Jr.↗

Mission Design for the Lunar Reconnaissance Orbiter

The Lunar Reconnaissance Orbiter (LRO) will be the first mission under NASA's Vision for Space Exploration. LRO will fly in a low 50 km mean altitude lunar polar orbit. LRO will utilize a direct minimum energy lunar transfer and have a launch window of three days every two weeks. The launch window is defined by lunar orbit beta angle at times of extreme lighting conditions. This paper will define the LRO launch window and the science and engineering constraints that drive it. After lunar orbit insertion, LRO will be placed into a commissioning orbit for up to 60 days. This commissioning orbit will be a low altitude quasi-frozen orbit that minimizes stationkeeping costs during commissioning phase. LRO will use a repeating stationkeeping cycle with a pair of maneuvers every lunar sidereal period. The stationkeeping algorithm will bound LRO altitude, maintain ground station contact during maneuvers, and equally distribute periselene between northern and southern hemispheres. Orbit determination for LRO will be at the 50 m level with updated lunar gravity models. This paper will address the quasi-frozen orbit design, stationkeeping algorithms and low lunar orbit determination.

Beckman, Mark↗

Effects of Topography on Tropical Forest Structure Depend on Climate Context

Topography affects abiotic conditions which can influence the structure, function, and dynamics of ecological communities. An increasing number of studies have demonstrated biological consequences of fine-scale topographic heterogeneity but we have a limited understanding of how We merged high-resolution (1 sq. meter) data on topography and canopy height derived from airborne lidar with ground-based data from 15 forest plots in Puerto Rico distributed along a precipitation gradient spanning ca. 800 to 3,500 mm yr(exp -1). Ground-based data included species composition, estimated above-ground biomass (AGB), and two key functional traits (wood density and leaf mass per area, LMA) that reflect resource-use strategies and a trade-off between hydraulic safety and hydraulic efficiency. We used hierarchical Bayesian models to evaluate how the interaction between topography climate is related to metrics of forest structure (i.e., canopy height and AGB), as well as taxonomic and functional alpha- and beta-diversity. Fine-scale topography (characterized with the topographic wetness index, TWI) significantly affected forest structure and the strength (and in some cases direction) of these effects varied across the precipitation gradient. In all plots, canopy height increased with topographic wetness but the effect was much stronger in dry compared to wet forest plots. In dry forest plots, topographically wetter microsites also had higher levels of AGB but in wet forest plots, topographically drier microsites had higher AGB. Fine-scale topography influenced functional composition but had only weak or non-significant effects on taxonomic and functional alpha- and beta-diversity. For instance, community-weighted wood density followed a similar pattern to AGB across plots. We also found a marginally significant association between variation of wood density and topographic heterogeneity that depended on climate context. Synthesis: The effects of fine-scale topographic heterogeneity on tropical forest structure and composition depend on the climate context. Our study demonstrates how a stronger integration of topographic heterogeneity across precipitation gradients could improve estimates of forest structure and biomass, and may provide insight to the ways that topography might mediate species responses to drought and climate change.

Tropical dry forest↗

The Paradox of Filamented Coronal Hole Flow but Uniform High Speed Wind

Plumes and rays in coronal holes are nearly radially aligned density striations that follow the ambient magnetic field. They have long been known, but have gained new interest with growing awareness that coronal hole flow is inherently filamentary. In retrospect, filamentary flow should have been no surprise. This is because,Beta much less than 1 in coronal holes inside approximately 10 Solar radius, allowing the flow to be filamentary down to the smallest scale of photospheric magnetic activity. While the magnetic field itself is locally smooth across any height above ca. 50,000 km, SOHO/MDI has shown that the photospheric magnetic field is a complex array of rapidly evolving small bipoles that are constantly emerging, evolving, and cancelling. The resulting activity is manifested in microflares, concentrated in the magnetic network, that produce Impulsive injections at the footpoints of coronal field lines. The uneven distribution of this activity in space and time is the source of coronal hole filamentation. What is surprising is that the radial flow speed also exhibits filamentary structure. It is not well described as smooth, spherically symmetric, diverging flow, but instead ranges from 300 to over 1000 km/s at 5.5 Solar radius among field-aligned filaments like those seen in plumes and rays [Feldman et al., JGR, Dec. 1997]. This is completely unlike the constant high speed solar wind reported beyond 0.3 AU. Consequently, plumes and filamentary structure must be strongly mixed, and the mixing must be far along by 0.3 AU to be consistent with Helios observations. The paradox is what causes the mixing? Existing models of coronal heating and solar wind acceleration hardly address this issue. One possibility we are investigating is the MHD Kelvin-Helmholtz instability, to which the shear between plumes and interplume corona is expected to become unstable at 5-10 Solar radius. This instability can be simulated and followed far into the nonlinear regime and may lead to Alfvenic fluctuations like those seen at 1 AU.

Suess, Steven T.↗

Measures and Interpretations of Vigilance Performance: Evidence Against the Detection Criterion

Operators' performance in a vigilance task is often assumed to depend on their choice of a detection criterion. When the signal rate is low this criterion is set high, causing the hit and false alarm rates to be low. With increasing time on task the criterion presumably tends to increase even further, thereby further decreasing the hit and false alarm rates. Virtually all of the empirical evidence for this simple interpretation is based on estimates of the bias measure Beta from signal detection theory. In this article, I describe a new approach to studying decision making that does not require the technical assumptions of signal detection theory. The results of this new analysis suggest that the detection criterion is never biased toward either response, even when the signal rate is low and the time on task is long. Two modifications of the signal detection theory framework are considered to account for this seemingly paradoxical result. The first assumes that the signal rate affects the relative sizes of the variances of the information distributions; the second assumes that the signal rate affects the logic of the operator's stopping rule. Actual or potential applications of this research include the improved training and performance assessment of operators in areas such as product quality control, air traffic control, and medical and clinical diagnosis.

Balakrishnan, J. D.↗

Snow and Ice Products from the Moderate Resolution Imaging Spectroradiometer

Snow and sea ice products, derived from the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument, flown on the Terra and Aqua satellites, are or will be available through the National Snow and Ice Data Center Distributed Active Archive Center (DAAC). The algorithms that produce the products are automated, thus providing a consistent global data set that is suitable for climate studies. The suite of MODIS snow products begins with a 500-m resolution, 2330-km swath snow-cover map that is then projected onto a sinusoidal grid to produce daily and 8-day composite tile products. The sequence proceeds to daily and 8-day composite climate-modeling grid (CMG) products at 0.05 resolution. A daily snow albedo product will be available in early 2003 as a beta test product. The sequence of sea ice products begins with a swath product at 1-km resolution that provides sea ice extent and ice-surface temperature (IST). The sea ice swath products are then mapped onto the Lambert azimuthal equal area or EASE-Grid projection to create a daily and 8-day composite sea ice tile product, also at 1 -km resolution. Climate-Modeling Grid (CMG) sea ice products in the EASE-Grid projection at 4-km resolution are planned for early 2003.

Hall, Dorothy K.↗

Secondary metabolism in simulated microgravity

We have studied microbial secondary metabolism in a simulated microgravity (SMG) environment provided by NASA rotating-wall bioreactors (RWBs). These reactors were designed to simulate some aspects of actual microgravity that occur in space. Growth and product formation were observed in SMG in all cases studied, i.e., Bacillus brevis produced gramicidin S (GS), Streptomyces clavuligerus made beta-lactam antibiotics, Streptomyces hygroscopicus produced rapamycin, and Escherichia coli produced microcin B17 (MccB17). Of these processes, only GS production was unaffected by SMG; production of the other three products was inhibited. This was determined by comparison with performance in an RWB positioned in a different mode to provide a normal gravity (NG) environment. Carbon source repression by glycerol of the GS process, as observed in shaken flasks, was not observed in the RWBs, whether operated in the SMG or NG mode. The same phenomenon occurred in the case of MccB17 production, with respect to glucose repression. Thus, the negative effects of carbon source on GS and beta-lactam formation are presumably dependent on shear, turbulence, and/or vessel geometry, but not on gravity. Stimulatory effects of phosphate and the precursor L-lysine on beta-lactam antibiotic production, as observed in flasks, also occurred in SMG. An almost complete shift in the localization of produced MccB17 from cells to extracellular medium was observed when E. coli was grown in the RWB under SMG or NG. If a plastic bead was placed in the RWB, accumulation became cellular, as it is in shaken flasks, indicating that sheer stress favors a cellular location. In the case of rapamycin, the same type of shift was observed, but it was less dramatic, i.e., growth in the RWB under SMG shifted the distribution of produced rapamycin from 2/3 cellular:1/3 extracellular to 1/3 cellular:2/3 extracellular. Stress has been shown to induce or promote secondary metabolism in a number of other microbial systems. RWBs provide a low stress SMG environment, which, however, supports only poor production of MccB17, as compared to production in shaken flasks. We wondered whether the poor production in RWBs under SMG is due to the low level of stress, and whether increasing stress in the RWBs would raise the amount of MccB17 formed. We found that increasing shear stress by adding a single Teflon bead to the RWB improved MccB17 production. Although shear stress seems to have a marked positive effect on MccB17 production in SMG, addition of various concentrations of ethanol to RWBs (or to shaken flasks) failed to increase MccB17 production. Ethanol stress merely decreased production and, at higher concentrations, inhibited growth. Interestingly, cells growing in the RWB were much more resistant to the growth- and production-inhibitory effects of ethanol than cells growing in shaken flasks. With respect to S. hygroscopicus, addition of Teflon beads to the RWB reversed the inhibition of growth, but rapamycin production was still markedly inhibited, and the distribution did not revert back to a preferential cellular site.

NASA Discipline Cell Biology↗

Characterization of the early pulmonary inflammatory response associated with PTFE fume exposure

Heating of polytetrafluoroethylene (PTFE) has been described to release fumes containing ultrafine particles (approximately 18 nm diam). These fumes can be highly toxic in the respiratory tract inducing extensive pulmonary edema with hemorrhagic inflammation. Fischer-344 rats were exposed to PTFE fumes generated by temperatures ranging from 450 to 460 degrees C for 15 min at an exposure concentration of 5 x 10(5) particles/cm3, equivalent to approximately 50 micrograms/m3. Responses were examined 4 hr post-treatment when these rats demonstrated 60-85% neutrophils (PMNs) in their lung lavage. Increases in abundance for messages encoding the antioxidants manganese superoxide dismutase and metallothionein (MT) increased 15- and 40-fold, respectively. For messages encoding the pro- and anti-inflammatory cytokines: inducible nitric oxide synthase, interleukin 1 alpha, 1 beta, and 6 (IL-1 alpha, IL-1 beta, and IL-6), macrophage inflammatory protein-2, and tumor necrosis factor-alpha (TNF alpha) increases of 5-, 5-, 10-, 40-, 40-, and 15-fold were present. Vascular endothelial growth factor, which may play a role in the integrity of the endothelial barrier, was decreased to 20% of controls. In situ sections were hybridized with 33P cRNA probes encoding IL-6, MT, surfactant protein C, and TNF alpha. Increased mRNA abundance for MT and IL-6 was expressed around all airways and interstitial regions with MT and IL-6 demonstrating similar spatial distribution. Large numbers of activated PMNs expressed IL-6, MT, and TNF alpha. Additionally, pulmonary macrophages and epithelial cells were actively involved. These observations support the notion that PTFE fumes containing ultrafine particles initiate a severe inflammatory response at low inhaled particle mass concentrations, which is suggestive of an oxidative injury. Furthermore, PMNs may actively regulate the inflammatory process through cytokine and antioxidant expression.

Non-NASA Center↗

The Moving Group Targets of the Seeds High-Contrast Imaging Survey of Exoplanets and Disks: Results and Observations from the First Three Years

We present results from the first three years of observations of moving group (MG) targets in the Strategic Exploration of Exoplanets and Disks with Subaru (SEEDS) high-contrast imaging survey of exoplanets and disks using the Subaru telescope. We achieve typical contrasts of (is) approximately10(exp 5) at 1" and (is) approximately 10(exp 6) beyond 2" around 63 proposed members of nearby kinematic MGs. We review each of the kinematic associations to which our targets belong, concluding that five, beta Pictoris ((is) approximately 20 Myr), AB Doradus ((is) approximately 100 Myr), Columba ((is) approximately 30 Myr), Tucana-Horogium ((is) approximately 30 Myr), and TW Hydrae ((is) approximately 10 Myr), are sufficiently well-defined to constrain the ages of individual targets. Somewhat less than half of our targets are high-probability members of one of these MGs. For all of our targets, we combine proposed MG membership with other age indicators where available, including Ca ii HK emission, X-ray activity, and rotation period, to produce a posterior probability distribution of age. SEEDS observations discovered a substellar companion to one of our targets, kappa And, a late B star. We do not detect any other substellar companions, but do find seven new close binary systems, of which one still needs to be confirmed. A detailed analysis of the statistics of this sample, and of the companion mass constraints given our age probability distributions and exoplanet cooling models, will be presented in a forthcoming paper.

SEEDS high-contrast imaging survey of exoplanets↗