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All sourcesNASA NTRSDOE OSTI
NASA NTRS1991

Scientific use of Space Station Freedom

The overall strategic science planning of the Office of Space Science and Applications (OSSA) is presented. The science opportunities inherent to the restructured Space Station are discussed and a synopsis of the OSSA implementation plan for Space Station Freedom utilization is offered. Attention is given to the microgravity science and applications facilities, the advanced protein crystal growth facility, the biotechnology facility, the modular combustion facility, and the life sciences facility.

Rhome, Robert C.↗
NASA NTRS1992

NASA's 'Mission to Planet Earth' begins with launch of UARS

The deployment of NASA's Upper Atmospher Research Satellite (UARS) is described in terms of the Shuttle flight and the expected contributions of the UARS to the 'Mission to Planet Earth'. The launch and daily activities of the Shuttle flight are described including microgravity-related materials experiments and the assembling of model space structures. The release of the UARS occurred without difficulty on the third day of the spaceflight, and experiments conducted included protein-crystal growth, middeck zero-gravity dynamics, rodent-physiology tests, cosmic radiation monitoring, and polymer-membrane processing. Millions of bytes of data resulted from the experiments conducted in space, and the UARS is expected to yield important data for the study of the global climate. The spaceflight culminated with the first nighttime landing at the Kennedy Space Center.

Schuiling, Roelof L.↗
NASA NTRS1991

Advances in space biology and medicine. Vol. 1

Topics discussed include the effects of prolonged spaceflights on the human body; skeletal responses to spaceflight; gravity effects on reproduction, development, and aging; neurovestibular physiology in fish; and gravity perception and circumnutation in plants. Attention is also given to the development of higher plants under altered gravitational conditions; the techniques, findings, and theory concerning gravity effects on single cells; protein crystal growth in space; and facilities for animal research in space.

Bonting, Sjoerd L.↗
NASA NTRS1993

NASA PPO microgravity projects support

Work progress is reported in brief. A summary of this information is provided below. An in-depth study was performed to evaluate a new European designed Borack Freezer/Cooler for possible shuttle middeck flight to support advanced protein crystal growth (APCG) experimentation. A statement of work was prepared for the design and development of a glovebox for proposed flight in the shuttle middeck. Work was also initiated to perform an analysis of low-g accelerometer data relative to Fluid Experiment System (FES) experiment options on the IML-1 mission. This work was undertaken in an effort to determine if abnormally low-g accelerations during the mission were responsible for anomalies which occurred during FES/Triglycine Sulfate (TGS) experiment operations. A comprehensive review was made on a revised edition of the Geophysical Fluid Flow Cell (GFFC) Operations and Maintenance (O&M) Manual.

Smith, Janice F.↗
NASA NTRS1992

Canadian Space Agency Space Station Freedom utilization plans

Under the terms of the NASA/CSA Memorandum of Understanding, Canada will contribute the Mobile Servicing System and be entitled to use 3 percent of all Space Station utilization resources and user accommodations over the 30 year life of the Station. Equally importantly Canada, like NASA, can begin to exploit these benefits as soon as the Man-Tended Capability (MTC) phase begins, in early 1997. Canada has been preparing its scientific community to fully utilize the Space Station for the past five years; most specifically by encouraging, and providing funding, in the area of Materials Science and Applications, and in the area of Space Life Sciences. The goal has been to develop potential applications and an experienced and proficient Canadian community able to effectively utilize microgravity environment facilities such as Space Station Freedom. In addition, CSA is currently supporting four facilities; a Laser Test System, a Large Motion Isolation Mount, a Canadian Float Zone Furnace, and a Canadian Protein Crystallization Apparatus. In late April of this year CSA sent out a Solicitation of Interest (SOI) to potential Canadian user from universities, industry, and government. The intent of the SOI was to determine who was interested, and the type of payloads which the community at large intended to propose. The SOI will be followed by the release of an Announcement of Opportunity (AO) following governmental approval of the Long Term Space plan later this year, or early next year. Responses to the AO will be evaluated and prioritized in a fair and impartial payload selection process, within the guidelines set by our international partners and the Canadian Government. Payload selection is relatively simple compared to the development and qualification process. An end-to-end user support program is therefore also being defined. Much of this support will be provided at the new headquarters currently being built in St. Hubert, Quebec. It is recognized that utilizing the Space Station could be expensive for users; costing in many cases millions of dollars to get a payload from conception to retrieval. It is also recognized that some of the potential users cannot or will not invest a lot of money or effort into Space Station utilization, unless there is a perceived significant commercial potential. How best to fund Space Station payloads is under study. Space Station Freedom will provide the first opportunity for Canada to conduct experiments in a long-duration microgravity environment. CSA have been developing and funding potential users for some time, and considerable interest has been shown by the response to our SOI earlier this year. Canada can be one of the two earliest users for the Space Station, along with NASA. We hope to take full advantage of this opportunity.

Faulkner, James↗
NASA NTRS1992

Commercial opportunities in bioseparations and physiological testing aboard Space Station Freedom

The Center for Cell Research (CCR) is a NASA Center for the Commercial Development of Space which has as its main goal encouraging industry-driven biomedical/biotechnology space projects. Space Station Freedom (SSF) will provide long duration, crew-tended microgravity environments which will enhance the opportunities for commercial biomedical/biotechnology projects in bioseparations and physiological testing. The CCR bioseparations program, known as USCEPS (for United States Commercial Electrophoresis Program in Space), is developing access for American industry to continuous-flow electrophoresis aboard SSF. In space, considerable scale-up of continuous free-flow electrophoresis is possible for cells, sub cellular particles, proteins, growth factors, and other biological products. The lack of sedemination and buoyancy-driven convection flow enhances purity of separations and the amount of material processed/time. Through the CCR's physiological testing program, commercial organizations will have access aboard SSF to physiological systems experiments (PSE's); the Penn State Biomodule; and telemicroscopy. Physiological systems experiments involve the use of live animals for pharmaceutical product testing and discovery research. The Penn State Biomodule is a computer-controlled mini lab useful for projects involving live cells or tissues and macro molecular assembly studies, including protein crystallization. Telemicroscopy will enable staff on Earth to manipulate and monitor microscopic specimens on SSF for product development and discovery research or for medical diagnosis of astronaut health problems. Space-based product processing, testing, development, and discovery research using USCEPS and CCR's physiological testing program offer new routes to improved health on Earth. Direct crew involvement-in biomedical/biotechnology projects aboard SSF will enable better experimental outcomes. The current data base shows that there is reason for considerable optimism regarding what the CCDS program and the biomedical/biotechnology industry can expect to gain from a permanent manned presence in space.

Hymer, W. C.↗
NASA NTRS1992

Materials dispersion and biodynamics project research

The Materials Dispersion and Biodynamics Project (MDBP) focuses on dispersion and mixing of various biological materials and the dynamics of cell-to-cell communication and intracellular molecular trafficking in microgravity. Research activities encompass biomedical applications, basic cell biology, biotechnology (products from cells), protein crystal development, ecological life support systems (involving algae and bacteria), drug delivery (microencapsulation), biofilm deposition by living organisms, and hardware development to support living cells on Space Station Freedom (SSF). Project goals are to expand the existing microgravity science database through experiments on sounding rockets, the Shuttle, and COMET program orbiters and to evolve,through current database acquisition and feasibility testing, to more mature and larger-scale commercial operations on SSF. Maximized utilization of SSF for these science applications will mean that service companies will have a role in providing equipment for use by a number of different customers. An example of a potential forerunner of such a service for SSF is the Materials Dispersion Apparatus (MDA) 'mini lab' of Instrumentation Technology Associates, Inc. (ITA) in use on the Shuttle for the Commercial MDAITA Experiments (CMIX) Project. The MDA wells provide the capability for a number of investigators to perform mixing and bioprocessing experiments in space. In the area of human adaptation to microgravity, a significant database has been obtained over the past three decades. Some low-g effects are similar to Earth-based disorders (anemia, osteoporosis, neuromuscular diseases, and immune system disorders). As new information targets potential profit-making processes, services and products from microgravity, commercial space ventures are expected to expand accordingly. Cooperative CCDS research in the above mentioned areas is essential for maturing SSF biotechnology and to ensure U.S. leadership in space technology. Currently, the MDBP conducts collaborative research with investigators at the Rockefeller University, National Cancer Institute, and the Universities of California, Arizona, and Alabama in Birmingham. The growing database from these collaborations provides fundamental information applicable to development of cell products, manipulation of immune cell response, bone cell growth and mineralization, and other processes altered by low-gravity. Contacts with biotechnology and biopharmaceutical companies are being increased to reach uninformed potential SSF users, provide access through the CMDS to interested users for feasibility studies, and to continue active involvement of current participants. We encourage and actively seek participation of private sector companies, and university and government researchers interested in biopharmaceuticals, hardware development and fundamental research in microgravity.

Lewis, Marian L.↗
NASA NTRS1993

Microgravity science and applications: Program tasks and bibliography for FY 1992

This report is a compilation of the FY 1992 Principal Investigator program task descriptions funded by the Microgravity Science and Applications Division (MSAD), NASA Headquarters, Washington, DC. The document also provides a bibliography of FY 1992 publications and presentations cited by MSAD Principal Investigators, and an index of the Principal Investigators and their affiliations. The purpose of the document is to provide an overview and progress report for the funded tasks for scientists and researchers in industry, university, and government communities. The tasks are grouped into three categories appropriate to the type of research being done-space flight, ground based, and advanced technology development-and by science discipline. The science disciplines are: biotechnology, combustion science,, electronic materials, fluid physics, fundamental physics, glass and ceramics, metals and alloys, and protein crystal growth.

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NASA NTRS1991

STS-37 Space Shuttle mission report

The STS-37 Space Shuttle Program Mission Report contains a summary of the vehicle subsystem activities during this thirty-ninth flight of the Space Shuttle and the eighth flight of the Orbiter Vehicle Atlantis (OV-104). In addition to the Atlantis vehicle, the flight vehicle consisted of the following: an External Tank (ET) (designated as ET-37/LWT-30); three Space Shuttle main engines (SSME's) (serial numbers 2019, 2031, and 2107 in positions 1, 2, and 3, respectively); and two Solid Rocket Boosters (SRB's) designated as BI-042. The primary objective of this flight was to successfully deploy the Gamma Ray Observatory (GRO) payload. The secondary objectives were to successfully perform all operations necessary to support the requirements of the Protein Crystal Growth (PCG) Block 2 version, Radiation Monitoring Experiment-3 (RME-3), Ascent Particle Monitor (APM), Shuttle Amateur Radio Experiment-2 (SAREX-2), Air Force Maui Optical Site Calibration Test (AMOS), Bioserve Instrumentation Technology Associates Materials Dispersion Apparatus (BIMDA), and the Crew and Equipment Transfer Aids (CETA) payloads.

Fricke, Robert W.↗
NASA NTRS1994

Microgravity sciences application visiting scientist program

Contract NAS8-38785, Microgravity Experimental and Theoretical Research, is a project involving a large number of individual research programs related to: determination of the structure of human serum albumin and other biomedically important proteins; analysis of thermodynamic properties of various proteins and models of protein nucleation; development of experimental techniques for the growth of protein crystals in space; study of the physics of electrical double layers in the mechanics of liquid interfaces; computational analysis of vapor crystal growth processes in microgravity; analysis of the influence of magnetic fields in damping residual flows in directional solidification processes; crystal growth and characterization of II-VI semiconductor alloys; and production of thin films for nonlinear optics. It is not intended that the programs will be necessarily limited to this set at any one time. The visiting scientists accomplishing these programs shall serve on-site at MSFC to take advantage of existing laboratory facilities and the daily opportunities for technical communications with various senior scientists.

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NASA NTRS1994

Thermal enclosure system functional simulation user's manual

A form and function simulation of the thermal enclosure system (TES) for a microgravity protein crystal growth experiment has been developed as part of an investigation of the benefits and limitations of intravehicular telerobotics to aid in microgravity science and production. A user can specify the time, temperature, and sample rate profile for a given experiment, and menu options and status are presented on an LCD display. This report describes the features and operational procedures for the functional simulation.

Morris, A. Terry↗
NASA NTRS1994

Vibration Isolation Technology (VIT) ATD Project

A fundamental advantage for performing material processing and fluid physics experiments in an orbital environment is the reduction in gravity driven phenomena. However, experience with manned spacecraft such as the Space Transportation System (STS) has demonstrated a dynamic acceleration environment far from being characterized as a 'microgravity' platform. Vibrations and transient disturbances from crew motions, thruster firings, rotating machinery etc. can have detrimental effects on many proposed microgravity science experiments. These same disturbances are also to be expected on the future space station. The Microgravity Science and Applications Division (MSAD) of the Office of Life and Microgravity Sciences and Applications (OLMSA), NASA Headquarters recognized the need for addressing this fundamental issue. As a result an Advanced Technology Development (ATD) project was initiated in the area of Vibration Isolation Technology (VIT) to develop methodologies for meeting future microgravity science needs. The objective of the Vibration Isolation Technology ATD project was to provide technology for the isolation of microgravity science experiments by developing methods to maintain a predictable, well defined, well characterized, and reproducible low-gravity environment, consistent with the needs of the microgravity science community. Included implicitly in this objective was the goal of advising the science community and hardware developers of the fundamental need to address the importance of maintaining, and how to maintain, a microgravity environment. This document will summarize the accomplishments of the VIT ATD which is now completed. There were three specific thrusts involved in the ATD effort. An analytical effort was performed at the Marshall Space Flight Center to define the sensitivity of selected experiments to residual and dynamic accelerations. This effort was redirected about half way through the ATD focusing specifically on the sensitivity of protein crystals to a realistic orbital environment. The other two thrusts of the ATD were performed at the Lewis Research Center. The first was to develop technology in the area of reactionless mechanisms and robotics to support the eventual development of robotics for servicing microgravity science experiments. This activity was completed in 1990. The second was to develop vibration isolation and damping technology providing protection for sensitive science experiments. In conjunction with the this activity, two workshops were held. The results of these were summarized and are included in this report.

Lubomski, Joseph F.↗
NASA NTRS1994

Materials processing in space tasks. WBS task 5.4: Generic tasks

This task encompassed a wide range of activities related to materials processing in space. For example, all aspects of the space station's flight and ground based systems design were assessed for the Office of Advanced Concepts and Technology (OACT) Space Processing Division Office. Activities for that organization also included the consolidation of space processing payload requirements for the space station and the development of an OACT payload operations plan. Similar duties were performed for the MSFC Payload Project Office. The SPACECOM database was used to conduct preliminary design studies for microgravity payload carriers and to conduct assessments of materials processing technology. Concepts for the Advanced Protein Crystal Growth Facility (APCGF) were developed. Materials processing vent products were analyzed and a furnace facility filter concept was developed using those studies. A preliminary design for a space station aluminum payload rack was developed. Analysis was conducted to characterize the acceleration environment onboard the space shuttle. Equipment for two fluid experiment apparatus was designed and manufactured for the Space Science Laboratory. The Fluids and Materials Experiments (FAME) data base was expanded. Also, Mir payload integration, technology transfer, and spacelab-to-space station transition studies were conducted.

Crull, Robert↗
NASA NTRS1994

Technology demonstration of space intravehicular automation and robotics

Automation and robotic technologies are being developed and capabilities demonstrated which would increase the productivity of microgravity science and materials processing in the space station laboratory module, especially when the crew is not present. The Automation Technology Branch at NASA Langley has been working in the area of intravehicular automation and robotics (IVAR) to provide a user-friendly development facility, to determine customer requirements for automated laboratory systems, and to improve the quality and efficiency of commercial production and scientific experimentation in space. This paper will describe the IVAR facility and present the results of a demonstration using a simulated protein crystal growth experiment inside a full-scale mockup of the space station laboratory module using a unique seven-degree-of-freedom robot.

Morris, A. Terry↗
NASA NTRS1994

Various advanced design projects promoting engineering education

The Universities Space Research Association (USRA) Advanced Design Program (ADP) program promotes engineering education in the field of design by presenting students with challenging design projects drawn from actual NASA interests. In doing so, the program yields two very positive results. Firstly, the students gain a valuable experience that will prepare them for design problems with which they will be faced in their professional careers. Secondly, NASA is able to use the work done by students as an additional resource in meeting its own design objectives. The 1994 projects include: Universal Test Facility; Automated Protein Crystal Growth Facility; Stiffening of the ACES Deployable Space Boom; Launch System Design for Access to Space; LH2 Fuel Tank Design for SSTO Vehicle; and Feed System Design for a Reduced Pressure Tank.

Source record↗
NASA NTRS1994

STS-68 Mission Highlights Resource Tape

The video contains important visual events including Space Radar Laboratory-2, Get Away Special canisters, Commercial Protein Crystal Growth, Biological Research in Canisters, Cosmic Radiation Effects and Activation Monitor, Military Applications of Ship Tracks, other onboard activities, earth views, and landing. Also includes Air-to-ground transmission between the crew and Mission control.

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NASA NTRS1994

STS-65 Space Shuttle mission report

The STS-65 Space Shuttle Program Mission Report summarizes the Payload activities as well as the Orbiter, External Tank (ET), Solid Rocket Booster (SRB), Redesigned Solid Rocket Motor (RSRM), and the Space Shuttle main engine (SSME) systems performance during the sixty-third flight of the Space Shuttle Program and the seventeenth flight of the Orbiter vehicle Columbia (OV-102). In addition to the Orbits the flight vehicle consisted of an ET that was designated ET-64; three SSME's that were designated as serial numbers 2019, 2030, and 2017 in positions 1, 2, and 3, respectively; and two SRB's that were designated Bl-066. The RSRM's that were installed in each SRB were designated as 360P039A for the left SRB, and 360W039 for the right SRB. The primary objective of this flight was to complete the operation of the second International Microgravity Laboratory (IML-2). The secondary objectives of this flight were to complete the operations of the Commercial Protein Crystal Growth (CPCG), Orbital Acceleration Research Experiment (OARE), and the Shuttle Amateur Radio Experiment (SAREX) II payloads. Additional secondary objectives were to meet the requirements of the Air Force Maui Optical Site (AMOS) and the Military Application Ship Tracks (MAST) payloads, which were manifested as payloads of opportunity.

Fricke, Robert W., Jr.↗