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At least 325 records · Page 18

Comparison of radiation exposure and associated radiation-induced cancer risks from mammography and molecular imaging of the breast

Purpose: Recent studies have raised concerns about exposure to low-dose ionizing radiation from medical imaging procedures. Little has been published regarding the relative exposure and risks associated with breast imaging techniques such as breast specific gamma imaging (BSGI), molecular breast imaging (MBI), or positron emission mammography (PEM). The purpose of this article was to estimate and compare the risks of radiation-induced cancer from mammography and techniques such as PEM, BSGI, and MBI in a screening environment. Methods: The authors used a common scheme for all estimates of cancer incidence and mortality based on the excess absolute risk model from the BEIR VII report. The lifetime attributable risk model was used to estimate the lifetime risk of radiation-induced breast cancer incidence and mortality. All estimates of cancer incidence and mortality were based on a population of 100 000 females followed from birth to age 80 and adjusted for the fraction that survives to various ages between 0 and 80. Assuming annual screening from ages 40 to 80 and from ages 50 to 80, the cumulative cancer incidence and mortality attributed to digital mammography, screen-film mammography, MBI, BSGI, and PEM was calculated. The corresponding cancer incidence and mortality from natural background radiation was calculated as a useful reference. Assuming a 15%-32% reduction in mortality from screening, the benefit/risk ratio for the different imaging modalities was evaluated. Results: Using conventional doses of 925 MBq Tc-99m sestamibi for MBI and BSGI and 370 MBq F-18 FDG for PEM, the cumulative cancer incidence and mortality were found to be 15-30 times higher than digital mammography. The benefit/risk ratio for annual digital mammography was >50:1 for both the 40-80 and 50-80 screening groups, but dropped to 3:1 for the 40-49 age group. If the primary use of MBI, BSGI, and PEM is in women with dense breast tissue, then the administered doses need to be in the range 75-150 MBq for Tc-99m sestamibi and 35 MBq-70 MBq for F-18 FDG in order to obtain benefit/risk ratios comparable to those of mammography in these age groups. These dose ranges should be achievable with enhancements to current technology while maintaining a reasonable examination time. Conclusions: The results of the dose estimates in this study clearly indicate that if molecular imaging techniques are to be of value in screening for breast cancer, then the administered doses need to be substantially reduced to better match the effective doses of mammography.

61 RADIATION PROTECTION AND DOSIMETRY↗

TeV gamma rays from 3C 279 - A possible probe of origin and intergalactic infrared radiation fields

The gamma-ray spectrum of 3C 279 during 1991 June exhibited a near-perfect power law between 50 MeV and over 5 GeV with a differential spectral index of -(2.02 +/- 0.07). If extrapolated, the gamma-ray spectrum of 3C 279 should be easily detectable with first-generation air Cerenkov detectors operating above about 0.3 TeV provided there is no intergalactic absorption. However, by using model-dependent lower and upper limits for the extragalactic infrared background radiation field, a sharp cutoff of the 3C 279 spectrum is predicted at between about 0.1 and about 1 TeV. The sensitivity of present air Cerenkov detectors is good enough to measure such a cutoff, which would provide the first opportunity to obtain a measurement of the extragalactic background infrared radiation field.

Stecker, F. W.↗

Design and Testing of a Novel Wide Range - Segmented Gamma Scanner Incorporating Tomographic Gamma Scanning for Measuring Both Low and Intermediate Level Waste in Drums - 13470

This paper describes the design and testing of a novel automated Wide Range Segmented Gamma ray Scanning (WR-SGS) assay instrument that also incorporates Tomographic Gamma Scanning (TGS). The instrument is designed for the measurement of both Low and Intermediate Level Waste (LLW and ILW) in 200 litre drums and other waste containers covering a wide range of density. Like earlier ANTECH WR-SGS instruments, the system employs a single shielded and collimated high purity germanium (HPGe) detector to quantify the radionuclide content of the waste and like conventional SGS instruments it is suitable for the measurement of relatively homogeneous waste matrices. Also, like earlier WR-SGS systems the instrument incorporates an automated variable aperture collimator, which allows the vertical segment height to be adjusted in order to measure both high dose-rate and very low activity drums. The instrument employs both conventional discrete SGS vertical segment measurements as well as vertical segment measurement by continuous helical-scanning of the drum as it rotates. This latter method reduces measurement times for SGS measurements. In order to determine the density corrections for both low and high-density drums, a high activity Eu-152 transmission source is employed. When not in use, and in place of a conventional shutter mechanism, the shielded transmission source is moved to a shielded storage position to eliminate background radiation from the source. Due to its novel features, the WR-SGS is applicable to the measurement of both very low and very high activity waste drums as well as waste drums with a wide range of density. If located in a low background position and with the effective shielding of the strong transmission source, the instrument can be used to measure very low level or exempt waste. In order to extend the range of applicability to the measurement of heterogeneous drums, TGS measurement capability has been included in the basic WR-SGS design. This is achieved by adding horizontal motion to the waste drum rotation platform and incorporating TGS collimation into the variable aperture collimator, as well as a filter to reduce the detector signal when straight-through measurements are made using the strong transmission source. Test measurements are presented of the system operating in both SGS and TGS modes using different drum densities and source strengths. The test measurement results are compared with benchmarked MCNP Monte Carlo calculations. The Wide Range SGS - TGS instrument extends the range of both activity and density that can be measured in 200 and 340 litre drums. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Reanalysis of the Apollo cosmic gamma-ray spectrum in the 0.3 to 10 MeV energy region

Additional data obtained from the Apollo-16 and -17 missions, together with collateral calculations on background radiation effects, have enabled an improved subtraction of unwanted backgrounds from the diffuse cosmic gamma-ray data previously reported from Apollo-15. As a result, the 1- to 10-MeV spectrum is lowered significantly and connects smoothly with recent data at other energies. The inflection reported previously is much less pronounced and has no more than a 1.5-sigma significance. Sky occultation by the Apollo-16 spacecraft shows the bulk of the 0.3- to 1-MeV radiation to be diffuse. The analysis of spurious backgrounds points to important improvements for future experiments designed for this spectral region.

Trombka, J. I.↗

Real breakthrough in detection of radioactive sources by portal monitors with plastic detectors and New Advanced Source Identification Algorithm (ASIA-New)

Radiation Portal Monitors (RPM) with plastic detectors represent the main instruments used for primary border (customs) radiation control. RPM are widely used because they are simple, reliable, relatively inexpensive and have a high sensitivity. However, experience using the RPM in various countries has revealed the systems have some grave shortcomings. There is a dramatic decrease of the probability of detection of radioactive sources under high suppression of the natural gamma background (radiation control of heavy cargoes, containers and, especially, trains). NORM (Naturally Occurring Radioactive Material) existing in objects under control trigger the so-called 'nuisance alarms', requiring a secondary inspection for source verification. At a number of sites, the rate of such alarms is so high it significantly complicates the work of customs and border officers. This paper presents a brief description of new variant of algorithm ASIA-New (New Advanced Source Identification Algorithm), which was developed by the Rapiscan company. It also demonstrates results of different tests and the capability of a new system to overcome the shortcomings stated above. New electronics and ASIA-New enables RPM to detect radioactive sources under a high background suppression (tested at 15-30%) and to verify the detected NORM (KCl) and the artificial isotopes (Co- 57, Ba-133 and other). New variant of ASIA is based on physical principles, a phenomenological approach and analysis of some important parameter changes during the vehicle passage through the monitor control area. Thanks to this capability main advantage of new system is that this system can be easily installed into any RPM with plastic detectors. Taking into account that more than 4000 RPM has been installed worldwide their upgrading by ASIA-New may significantly increase probability of detection and verification of radioactive sources even masked by NORM. This algorithm was tested for 1,395 passages of different transports (cars, trucks and trailers) without radioactive sources. It also was tested for 4,015 passages of these transports with radioactive sources of different activity (Co-57, Ba-133, Cs-137, Co-60, Ra-226, Th-232) and these sources masked by NORM (K-40) as well. (authors)

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

New Advanced Source Identification Algorithm (ASIA-NEW) for radiation monitors with plastic detectors

Radiation Portal Monitors (RPM) with plastic detectors represent the main instruments used for primary border (customs) radiation control. RPM are widely used because they are simple, reliable, relatively inexpensive and have a high sensitivity. However, experience using the RPM in various countries has revealed the systems have some grave shortcomings. There is a dramatic decrease of the probability of detection of radioactive sources under high suppression of the natural gamma background (radiation control of heavy cargoes, containers and, especially, trains). NORM (Naturally Occurring Radioactive Material) existing in objects under control trigger the so-called 'nuisance alarms', requiring a secondary inspection for source verification. At a number of sites, the rate of such alarms is so high it significantly complicates the work of customs and border officers. This paper presents a brief description of new variant of algorithm ASIA-New (New Advanced Source Identification Algorithm), which was developed by the authors and based on some experimental test results. It also demonstrates results of different tests and the capability of a new system to overcome the shortcomings stated above. New electronics and ASIA-New enables RPM to detect radioactive sources under a high background suppression (tested at 15-30%) and to verify the detected NORM (KCl) and the artificial isotopes (Co-57, Ba-133 and other). New variant of ASIA is based on physical principles and does not require a lot of special tests to attain statistical data for its parameters. That is why this system can be easily installed into any RPM with plastic detectors. This algorithm was tested for 1,395 passages of different transports (cars, trucks and trailers) without radioactive sources. It also was tested for 4,015 passages of these transports with radioactive sources of different activity (Co-57, Ba-133, Cs-137, Co-60, Ra-226, Th-232) and these sources masked by NORM (K-40) as well. (authors)

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Model of interacting holographic dark energy at the Ricci scale

We study a holographic cosmological model in which the infrared cutoff is set by the Ricci length and dark matter and dark energy do not evolve on their own but interact nongravitationally with each other. This greatly alleviates the cosmic coincidence problem because the ratio between both components does not vanish at any time. We constrain the model with observational data from supernovae, cosmic background radiation, baryon acoustic oscillations, gas mass fraction in galaxy clusters, the history of the Hubble function, and the growth function.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Experiments with compton back scattered gamma beams (on GRAAL collaboration results)

Experimental study of photonuclear reactions using Compton back scattered gamma beams at intermediate energies (from pion photoproduction threshold up to a few GeV) is reviewed. The last review of this subject was published about 10 years ago. Since then, new fundamental data on nucleon spin structure and photonuclear excitation mechanisms have appeared in the literature. Principal attention in the present review is paid to the GRAAL (Grenoble Accelerateur Anneau Laser) experiment conducted at ESRF (European Synchrotron Radiation Facility). It is shown that, in addition to the principal polarization experimental program based on high degree of gamma beam polarization, new results on different applications have been obtained. For example, total photoabsorption and partial meson photoproduction cross sections were measured with high accuracy, and a new method for studying an interaction of unstable short-lived mesons with nuclear media (tagged mesons) was proposed. New results on anisotropy of the speed of light with respect to the dipole of cosmic microwave background radiation were evaluated. It is noted that new opportunities arise due to unique conditions appearing while conducting the experiments with the Compton back scattering technique, which provides the hard photon spectrum, high degree of beam polarization, and low backgrounds.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Neutrino masses, neutrino oscillations, and cosmological implications

Theoretical concepts and motivations for considering neutrinos having finite masses are discussed and the experimental situation on searches for neutrino masses and oscillations is summarized. The solar neutrino problem, reactor, deep mine and accelerator data, tri decay experiments and double beta-decay data are considered and cosmological implications and astrophysical data relating to neutrino masses are reviewed. The neutrino oscillation solution to the solar neutrino problem, the missing mass problem in galaxy halos and galaxy cluster galaxy formation and clustering, and radiative neutrino decay and the cosmic ultraviolet background radiation are examined.

Stecker, F. W.↗

Bolometric detector systems for IR and mm-wave space astronomy

Recent developments in bolometric detector systems for millimeter and submillimeter wave space astronomy are described. Current technologies meet all the requirements for the high frequency instrument onboard the cosmic background radiation anisotropy satellite/satellite for the measurement of background anisotropies (COBRAS/SAMBA) platform. It is considered that the technologies that are currently being developed will significantly reduce the effective time constant and/or the cooling requirements of bolometric detectors. These technologies lend themselves to the fabrication of the large format arrays required for the Far Infrared and Submillimeter Space Telescope (FIRST). The scientific goals and detector requirements of the COBRAS/SAMBA platform that will use infrared bolometers are reviewed and the baseline detector system is described, including the feed optics, the infrared filters, the cold amplifiers and the warm readout electronics.

Church, S. E.↗

Decay of long-lived particles in the early universe

It is pointed out that radiative decay of massive fermions can distort the cosmic background radiation. The present investigation is concerned with a study of decay lifetimes in the range from 10 to 100,000 years. Attention is given to the physics involved in determining the effect of radiative decay of massive fermions on observed photon backgrounds. The case of particles which decoupled when the effective number of species in equilibrium was in the range from 50 to 100 is considered, and constraints on particle masses and lifetimes are placed on the basis of observed photon fluxes. This approach provides results with special applications to particles predicted by supersymmetry theories and to right-handed neutrinos. Implications for galaxy formation are also discussed.

Silk, J.↗

Galaxy formation by mock gravity with dust?

Absorbing dust immersed in an isotropic radiation field experiences an attractive force, 'mock gravity', due to mutual shadowing, and the resulting mock gravitational instability can lead to clumping of dust and gas. The effects of mock gravity in the pre-Galactic universe are studied here, including imcomplete coupling of dust and gas, finite gas pressure, radiative drag both by the radiation that causes the instability and by the cosmic microwave background radiation, and finite albedo of dust, all of which have been neglected in the previous calculations. It is concluded that the radiation field implied by the submillimeter background is not strong enough to cause clumping of gas on scales of interest.

Wang, Boqi↗

Gauging Metallicity of Diffuse Gas under an Uncertain Ionizing Radiation Field

Gas metallicity is a key quantity used to determine the physical conditions of gaseous clouds in a wide range of astronomical environments, including interstellar and intergalactic space. In particular, considerable effort in circumgalactic medium (CGM) studies focuses on metallicity measurements because gas metallicity serves as a critical discriminator for whether the observed heavy ions in the CGM originate in chemically enriched outflows or in more chemically pristine gas accreted from the intergalactic medium. However, because the gas is ionized, a necessary first step in determining CGM metallicity is to constrain the ionization state of the gas which, in addition to gas density, depends on the ultraviolet background radiation field (UVB). While it is generally acknowledged that both the intensity and spectral slope of the UVB are uncertain, the impact of an uncertain spectral slope has not been properly addressed in the literature. This Letter shows that adopting a different spectral slope can result in an order of magnitude difference in the inferred CGM metallicity. Specifically, a harder UVB spectrum leads to a higher estimated gas metallicity for a given set of observed ionic column densities. Therefore, such systematic uncertainties must be folded into the error budget for metallicity estimates of ionized gas. An initial study shows that empirical diagnostics are available for discriminating between hard and soft ionizing spectra. Applying these diagnostics helps reduce the systematic uncertainties in CGM metallicity estimates.

79 ASTRONOMY AND ASTROPHYSICS↗

Exploring communication techniques across a wide spectrum of groups - 15105

Communication about radionuclide and nuclear waste is one factor in facilitating decisions regarding environmental issues and energy solutions. However, the decision process involves many people with a variety of perceptions that have been formed throughout many years. This paper describes various communication techniques across a spectrum of stakeholders from the general public, students, first responders, analysts, and decisions makers. Techniques include dose assessment tools, assessment training, preparing first responders to confront potential radiological/nuclear situations, web multimedia information, ongoing Department of Energy (DOE) education projects, public talks and presentations, and National Environmental Policy Act (NEPA) participation. Issues are identified concerning perception including units, background radiation, effects of environmental levels of radiation, potential approaches to energy literacy, and risk comparison. These various communication techniques across a spectrum of stakeholders are evaluated with feedback and use statistics concerning aspects of strategies, challenges, and common perceptions. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

FLUX AND PHOTON SPECTRAL INDEX DISTRIBUTIONS OF FERMI-LAT BLAZARS AND CONTRIBUTION TO THE EXTRAGALACTIC GAMMA-RAY BACKGROUND

We present a determination of the distributions of the photon spectral index and gamma-ray flux-the so-called log N-log S relation-for the 352 blazars detected with a greater than approximately 7{sigma} detection threshold and located above {+-}20 Degree-Sign Galactic latitude by the Large Area Telescope of the Fermi Gamma-ray Space Telescope in its first year catalog. Because the flux detection threshold depends on the photon index, the observed raw distributions do not provide the true log N-log S counts or the true distribution of the photon index. We use the non-parametric methods developed by Efron and Petrosian to reconstruct the intrinsic distributions from the observed ones which account for the data truncations introduced by observational bias and includes the effects of the possible correlation between the two variables. We demonstrate the robustness of our procedures using a simulated data set of blazars and then apply these to the real data and find that for the population as a whole the intrinsic flux distribution can be represented by a broken power law with high and low indices of -2.37 {+-} 0.13 and -1.70 {+-} 0.26, respectively, and the intrinsic photon index distribution can be represented by a Gaussian with mean of 2.41 {+-} 0.13 and width of 0.25 {+-} 0.03. We also find the intrinsic distributions for the sub-populations of BL Lac and flat spectrum radio quasar type blazars separately. We then calculate the contribution of Fermi blazars to the diffuse extragalactic gamma-ray background radiation. Under the assumption that the flux distribution of blazars continues to arbitrarily low fluxes, we calculate the best-fit contribution of all blazars to the total extragalactic gamma-ray output to be 60%, with a large uncertainty.

79 ASTRONOMY AND ASTROPHYSICS↗

Improved microwave SQUID multiplexer readout using a kinetic-inductance traveling-wave parametric amplifier

We report on the use of a kinetic-inductance traveling-wave parametric amplifier (KITWPA) as the first amplifier in the readout chain of a microwave superconducting quantum interference device (SQUID) multiplexer (μmux). This μmux is designed to multiplex signals from arrays of low temperature detectors, such as superconducting transition-edge sensor microcalorimeters. When modulated with a periodic flux-ramp to linearize the SQUID response, the flux noise improves, on average, from 1.6 μ $\Phi$ 0 /$\sqrt{Hz}$ with the KITWPA off to 0.77 μ $\Phi$ 0 /$\sqrt{Hz}$ with the KITWPA on. When statically biasing the μmux to the maximally flux-sensitive point, the flux noise drops from 0.45 μ $\Phi$ 0 /$\sqrt{Hz}$ to 0.2 μ $\Phi$ 0 /$\sqrt{Hz}$⁠. We validate this new readout scheme by coupling a transition-edge sensor microcalorimeter to the μmux and detecting background radiation. In conclusion, the combination of μmux and KITWPA provides a variety of new capabilities including improved detector sensitivity and more efficient bandwidth utilization.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Single-Photon Counting in Luminescent Analysis with Micro- and Millisecond Decay Times

Main methods of photon counting, as well as particularities in detecting micro- and millisecond decay times using a single-photon gated avalanche photodiode, are considered. The influence of the background radiation level on linearity of counting has been determined and the effect of photon superposition during asynchronous counting has been demonstrated. In addition, recommendations for the detection of long-living or delayed fluorescence and phosphorescence are presented.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Plasma characterization using ultraviolet Thomson scattering from ion-acoustic and electron plasma waves (invited)

Collective Thomson scattering is a technique for measuring the plasma conditions in laser-plasma experiments. Simultaneous measurements of ion-acoustic and electron plasma-wave spectra were obtained using a 263.25-nm Thomson-scattering probe beam. A fully reflective collection system was used to record light scattered from electron plasma waves at electron densities greater than 10{sup 21} cm{sup −3}, which produced scattering peaks near 200 nm. An accurate analysis of the experimental Thomson-scattering spectra required accounting for plasma gradients, instrument sensitivity, optical effects, and background radiation. Practical techniques for including these effects when fitting Thomson-scattering spectra are presented and applied to the measured spectra to show the improvements in plasma characterization.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗