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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 307 records · Page 17

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DOE OSTI2018

Ex Situ Catalytic Fast Pyrolysis of Lignocellulosic Biomass to Hydrocarbon Fuels: 2018 State of Technology and Future Research

This report will update modeled costs for a fixed bed ex situ catalytic fast pyrolysis process for the conversion of biomass to liquid hydrocarbon fuels based on recent bench-scale experimental results. It will also update previously published information for this conversion pathway in the DOE Bioenergy Technologies Office 2016 Multi-Year Program Plan with current understanding of research goals achievable by 2022 and associated modeled cost reductions. All costs will be updated to a consistent set of assumptions in 2016 dollars.

09 BIOMASS FUELS↗

DOE OSTI2018

High-Octane Gasoline from Lignocellulosic Biomass via Syngas and Methanol/Dimethyl Ether Intermediates: 2018 State of Technology and Future Research

This report will update modeled costs for the production of high-octane gasoline via gasification of biomass followed by syngas cleanup and conversion to methanol/dimethyl ether. The 2018 State of Technology will be based on recent bench-scale experimental results. This report will also update previously published information for this conversion pathway in the DOE Bioenergy Technologies Office 2016 Multi-Year Program Plan with current understanding of research goals achievable by 2022 and associated modeled cost reductions. All costs will be updated to a consistent set of assumptions in 2016 dollars.

09 BIOMASS FUELS↗

DOE OSTI2020

Addressing Human and Organizational Factors in Nuclear Industry Modernization: An Operationally Focused Approach to Process and Methodology

Utility owners and operators of commercial nuclear power plants in the United States (U.S.) are and will be modernizing their nuclear power plants by performing a digital transformation involving design of an integrated set of systems that together enable a technology centric operating plant. The Plant Modernization Pathway of the U.S. Department of Energy Light Water Reactor Sustainability Program has a strategic action plan that lays the groundwork for a digital transformation of the nuclear industry. The model for this transformation is an advanced concept of operations, with an end point vision, “To achieve the maximum aggregate benefit enabled by this digital transformation.” To achieve this, the digital infrastructure for a nuclear plant must be designed as an integrated set of systems that together enable a technology centric operating model. The digital transformation process obviously needs to involve technology considerations and systems engineering, but it also needs to include human and organizational expertise. Thus, human and organizational factors, including sociotechnical systems methods and techniques (e.g., Cognitive Systems Engineering, Systems Theoretic Accident Modeling and Processes, human systems integration, and Macroergonomics) need to be considered for digital transformation projects in order to effectively integrate human and organizational expertise efforts into the new work system that results from nuclear power plant digital modernization. That is, the work system is the basic unit of sociotechnical systems analysis and contains three components: personnel, technical, and organization and management. These components should be jointly optimized with respect to the interdependence of systems performance criteria of effectiveness, efficiency and safety. Joint optimization can be achieved through the application of three human and organization functions: knowledge representation, knowledge elicitation, and cross-functional integration. This report provides a strategic framework for effective integration of human and organizational expertise within nuclear power plant digital modernization efforts.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

DOE OSTI2021

A Multi-Scale Inference, Estimation, and Prediction Engine for Earth System Modeling

We posit that AI methods can be leveraged to significantly enhance the predictive skill of forward Earth system modeling (ESM) activities. A hybrid framework incorporating traditional ESM modeling, inference methods, and AI techniques could make better use of both measured and computed information as well as computational resources by targeting inference tasks at program priorities, such as the predictability of precipitation extremes. This runtime pathway to closing the simulation/analysis-data/model improvement loop will streamline the traditional offline pathway to model improvement, which is based on domain science expertise, while suggesting guidance for further observations and measurements.

58 GEOSCIENCES↗

NASA NTRS2003

An On-line Technology Information System (OTIS) for Advanced Life Support

OTIS is an on-line communication platform designed for smooth flow of technology information between advanced life support (ALS) technology developers, researchers, system analysts, and managers. With pathways for efficient transfer of information, several improvements in the ALS Program will result. With OTIS, it will be possible to provide programmatic information for technology developers and researchers, technical information for analysts, and managerial decision support. OTIS is a platform that enables the effective research, development, and delivery of complex systems for life support. An electronic data collection form has been developed for the solid waste element, drafted by the Solid Waste Working Group. Forms for other elements (air revitalization, water recovery, food processing, biomass production and thermal control) will also be developed, based on lessons learned from the development of the solid waste form. All forms will be developed by consultation with other working groups, comprised of experts in the area of interest. Forms will be converted to an on-line data collection interface that technology developers will use to transfer information into OTIS. Funded technology developers will log in to OTIS annually to complete the element- specific forms for their technology. The type and amount of information requested expands as the technology readiness level (TRL) increases. The completed forms will feed into a regularly updated and maintained database that will store technology information and allow for database searching. To ensure confidentiality of proprietary information, security permissions will be customized for each user. Principal investigators of a project will be able to designate certain data as proprietary and only technical monitors of a task, ALS Management, and the principal investigator will have the ability to view this information. The typical OTIS user will be able to read all non-proprietary information about all projects.Interaction with the database will occur over encrypted connections, and data will be stored on the server in an encrypted form. Implementation of OTIS will initiate a community-accessible repository of technology development information. With OTIS, ALS element leads and managers will be able to carry out informed technology selection for programmatic decisions. OTIS will also allow analysts to make accurate evaluations of technology options. Additionally, the range and specificity of information solicited will help educate technology developers of program needs. With augmentation, OTIS reporting is capable of replacing the current fiscal year-end reporting process. Overall, the system will enable more informed R&TD decisions and more rapid attainment of ALS Program goals.

Levri, Julie A.↗

NASA NTRS2016

Unpredictable Variable Prenatal Stress Programs Expression of Genes Involved in Appetite Control and Energy Expenditure

Prenatal Stress↗

NASA NTRS2016

Unpredictable Variable Prenatal Stress Programs Expression of Genes Involved in Appetite Control and Energy Expenditure

Exposure to stress in the womb shapes neurobiological and physiological outcomes of offspring in later life, including body weight regulation and metabolic profiles. Our previous work utilizing a centrifugation-induced hypergravity demonstrated significantly increased (8-15) body mass in male, but not female, rats exposed throughout gestation to chronic 2-g from conception to birth. We reported the same outcome in adult offspring exposed throughout gestation to Unpredictable Variable Prenatal Stress (UVPS). Here we examine gene expression changes using our UVPS model to identify a potential role for prenatal stress in this hypergravity programming effect. Specifically we focused on appetite control and energy expenditure pathways in prenatally stressed adult (90-day-old) male Sprague-Dawley rats. Time-mated female rats were exposed throughout their 22-day pregnancy to UVPS consisting of white noise, strobe light, and tube restraint individually once per day on an unpredictable schedule for 15, 30 or 60 min. To control for potential changes in postnatal maternal care, newborn pups were fostered to non-manipulated, newly parturient dams. At 90-days of age, we analyzed plasma concentrations of hormones involved in appetite control and energy expenditure (leptin and adiponectin), and quantified expression of key genes in epididymal fat pads harvested from adult male offspring and controls. Leptin regulates energy balance by inhibiting hunger, and adiponectin modulates glucose levels and fatty acid breakdown. Our findings indicate significantly elevated plasma leptin concentrations and reduced expression of epididymal fat leptin (OB) and adiponectin (ADIPOQ) genes compared to controls. Analyses presently underway include quantification of plasma insulin and glucose, and the expression of ghrelin, a peptide that acts on the central nervous system and the body's perception of hunger. Collectively, these findings will further understanding of the consequences of UVPS on body weight regulation and metabolism, and provide further insight into the effect of gravity modulation on mammalian fetal development.

Appetite Control↗

DOE OSTI2022

Development of Surveillance Test Articles for Materials Degradation Management in MSR Environment

Information on materials degradations during advanced reactor operations is limited Effects of materials degradations during reactor operations are synergistic, involving: Irradiation, corrosion, elevated temperature exposure and stress (creep-fatigue loading) Establishment of surrogate materials surveillance program for the management of materials degradations would be an important pathway in support of the timely licensing of advanced reactors

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

DOE OSTI2022

Energy Management Information Systems Cybersecurity Best Practices

Energy management information systems (EMIS) are a broad and rapidly evolving family of tools that monitor, analyze, and control building energy use and system performance. Critical systems are often integrated with or operate on the same networks as EMIS scope systems, necessitating stable, continuous, and secure communication. When connecting EMIS to building automation and utility control systems, there are also many physical assets that could cause harm to the building and its occupants if a malicious act or human error were introduced. It is imperative to ensure all EMIS scope systems are connected securely to the EMIS and do not open vulnerable pathways to other facility networks and operations. The Federal Energy Management Program (FEMP) promotes best practices for impactful utilization of EMIS at federal facilities. This best practice document is part of a series of fact sheets created to help accelerate the market adoption and use of EMIS in the federal sector. It provides an overview of required EMIS cybersecurity standards for compliance and authority to operate along with additional recommendations.

cybersecurity↗

DOE OSTI2022

Energy Management Information Systems Cybersecurity Best Practices

Cybersecurity↗

DOE OSTI2024

Zero-Emission Vehicle Adoption Resource Guide for Government Fleets in Jackson County, Illinois

As part of Communities LEAP (Local Energy Action Program), the National Renewable Energy Laboratory (NREL) provided technical assistance to Jackson County, Illinois to help develop their clean energy transition roadmap. Fleet electrification was identified as a potential pathway that could address the environmental injustices, high energy burden, and local pollution experienced by this former coal community. NREL worked with Jackson County, Illinois to develop a resource guide that can assist fleet managers considering a transition to electric light-duty fleet vehicles. To further understand the unique challenges of fleet electrification in Jackson County, NREL met with three leaders within the county who either managed current fleets or were responsible for fleet purchases. This resource guide includes best practices and resources that address many of the frequently asked questions that arose during these discussions. Interested fleets can then use this resource guide to help identify the initial steps needed to plan for vehicle electrification. The resource guide summarizes the basics of electric vehicle (EV) adoption for fleets, funding and incentive pathways, total cost of ownership in comparison to conventional internal combustion engine (ICE) vehicles, charging infrastructure, and pilot programs.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

DOE OSTI2021

Energy I-Corps Electron Beam (EB) Potential for International Trade of Logs

The purpose of this document is to capture the potential from Fermilab’s “Team EB Treement” at the DOE Energy I-Corps program. Energy I-Corps, a key initiative of the Office of Technology Transitions, pairs teams of researchers with industry mentors for an intensive two-month training where the researchers define technology value propositions, conduct customer discovery interviews, and develop viable market pathways for their technologies. The team was composed prior to the Energy I-Corp program; however, the program was a catalyst for education and information exchange between the team members and stakeholders, customers, and regulators. These exchanges were captured in the evolution of a Business Model Canvas (BMC) and a Value Proposition (VP). The BMC and VP underwent numerous transformations based on feedback from the conversations between members of the team and forest or agriculture industry stakeholders and the program instructors.

43 PARTICLE ACCELERATORS↗

DOE OSTI2014

5-(2-Carboxyethenyl) isatin derivative induces G{sub 2}/M cell cycle arrest and apoptosis in human leukemia K562 cells

Highlights: • 5-(2-Carboxyethenyl) isatin derivative (HKL 2H) inhibited K562’s proliferation. • HKL 2H caused the morphology change of G{sub 2}/M phase arrest and typical apoptosis. • HKL 2H induced G2/M cell cycle phase arrest in K562 cells. • HKL 2H induced apoptosis in K562 cells through the mitochondrial pathway. - Abstract: Our previous study successfully identified that the novel isatin derivative (E)-methyl 3-(1-(4-methoxybenzyl)-2,3-dioxoindolin-5-yl) acrylate (HKL 2H) acts as an anticancer agent at an inhibitory concentration (IC{sub 50}) level of 3 nM. In this study, the molecular mechanism how HKL 2H induces cytotoxic activity in the human chronic myelogenous leukemia K562 cells was investigated. Flow cytometric analysis showed that the cells were arrested in the G{sub 2}/M phase and accumulated subsequently in the sub-G{sub 1} phase in the presence of HKL 2H. HKL 2H treatment down-regulated the expressions of CDK1 and cyclin B but up-regulated the level of phosphorylated CDK1. Annexin-V staining and the classic DNA ladder studies showed that HKL 2H induced the apoptosis of K562 cells. Our study further showed that HKL 2H treatment caused the dissipation of mitochondrial membrane potential, activated caspase-3 and lowered the Bcl-2/Bax ratio in K562 cells, suggesting that the HKL 2H-causing programmed cell death of K562 cells was caused via the mitochondrial apoptotic pathway. Taken together, our data demonstrated that HKL 2H, a 5-(2-carboxyethenyl) isatin derivative, notably induces G{sub 2}/M cell cycle arrest and mitochondrial-mediated apoptosis in K562 cells, indicating that this compound could be a promising anticancer candidate for further investigation.

60 APPLIED LIFE SCIENCES↗

DOE OSTI2026

Metabolic flux and resource balance in the oleaginous yeast Rhodotorula toruloides

The yeast Rhodotorula toruloides is a promising bioproduction organism due to its high lipid yields and ability to grow on cheap and abundant substrates. Quantitative, systems-level assessment of its metabolic activity is accordingly merited. Resource-balance analysis (RBA) models capture not only reaction stoichiometry but also enzyme requirements for catalysis, providing valuable tools for understanding metabolic trade-offs and optimizing metabolic engineering strategies. Here, in this work, we present systems-level measurements of R. toruloides metabolic flux based on isotope tracing and metabolic flux analysis. In combination with new proteomic measurements, these flux data are used to parameterize a genome-scale resource balance model rtRBA. We find that S. cerevisiae and R. toruloides grow at nearly indistinguishable rates using similar biosynthetic but dramatically different central metabolic programs. R. toruloides consumes one-fifth as much glucose, which it metabolizes primarily via the pentose phosphate pathway and TCA cycle unlike primarily glycolysis in S. cerevisiae . Overall, across these two divergent yeasts, protein abundances aligned more closely than metabolic flux. Resource balance modeling of these metabolic programs predicts superior theoretical yields but lower productivities in R. toruloides than S. cerevisiae for industrial chemicals, highlighting the value of rapid glucose uptake for productivity but respiratory metabolism for yields.

60 APPLIED LIFE SCIENCES↗

DOE OSTI2018

How Successful Site Preparation Work at a Large, Commercial, Hazardous and Toxic Waste Site Can Benefit DOE Cleanup Projects - 18111

Jacobs recently completed site preparation work supporting the private commercial development of a world-scale petrochemical complex (an 'ethylene cracker' to produce the primary building block for many forms of plastic) in Monaca, Pennsylvania - the first major U.S. project of its kind outside the Gulf Coast region in 20 years and one of the largest (multi-billion dollar) construction projects in the eastern U.S. Prior to beginning construction on the petrochemical complex, the site's previous large, industrial zinc smelter operations had to be decommissioned and the facilities had to be removed. During the previous 80 years, the smelting operations at the site were used to produce zinc, lead, mercury, and sulfuric acid (a by-product of smelting). The smelting operations left landfills and industrial soil over a large area that had to be removed or closed under regulatory review to allow development across the 81,000 m{sup 2} (200-acre) industrial site located near a major river and local populations. In order to meet Pennsylvania's site-specific Land Recycling Program (commonly referred to as 'Act 2') legislative requirements, the direct contact pathway for landfill soil and slag was removed or mitigated. The site preparation work, or 'Early Works', started in January 2015. As the selected Early Works overall Engineering, Procurement, and Construction Management (EPCM) contractor, Jacobs performed the front end engineering and design. Subsequently, Jacobs had overall responsibility for procurement, construction management, health and safety, quality, security, and environmental services for the entire site and all contractors. The Early Works project included eight separate work scope packages: 1) Site Preparation, 2) Site Development, 3) Marine Works, 4) Rail Works, 5) Road Works and Offsite Utilities, 6) Site Security, 7) Construction Facilities, and 8) High Voltage Line Relocation. The Early Works scope was successfully completed in 2017. The challenges faced by this privately funded commercial project have much in common with large DOE and government construction projects. This paper explores lessons learned from the project and compares how project challenges were addressed on this private commercial project with those anticipated at large DOE/government construction and remediation sites, particularly those in the areas of Safety, Logistics, Infrastructure, and Stakeholder Involvement. The identification of best practices demonstrated on this successful project are shared for the purpose of bringing outside, commercial perspectives to ongoing or planned DOE/government construction projects. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

DOE OSTI2017

From Policy to Compliance: Federal Energy Efficient Product Procurement

Federal buyers are required to purchase energy-efficient products in an effort to minimize energy use in the federal sector, save the federal government money, and spur market development of efficient products. The Federal Energy Management Program (FEMP)’s Energy Efficient Product Procurement (EEPP) Program helps federal agencies comply with the requirement to purchase energy-efficient products by providing technical assistance and guidance and setting efficiency requirements for certain product categories. Past studies have estimated the savings potential of purchasing energy-efficient products at over $500 million per year in energy costs across federal agencies.1 Despite the strong policy support for EEPP and resources available, energy-efficient product purchasing operates within complex decision-making processes and operational structures; implementation challenges exist that may hinder agencies’ ability to comply with purchasing requirements. The shift to purchasing green products, including energy-efficient products, relies on “buy in” from a variety of potential actors throughout different purchasing pathways. Challenges may be especially high for EEPP relative to other sustainable acquisition programs given that efficient products frequently have a higher first cost than non-efficient ones, which may be perceived as a conflict with fiscal responsibility, or more simply problematic for agency personnel trying to stretch limited budgets. Federal buyers may also face challenges in determining whether a given product is subject to EEPP requirements. Previous analysis on agency compliance with EEPP, conducted by the Alliance to Save Energy (ASE), shows that federal agencies are getting better at purchasing energy-efficient products. ASE conducted two reviews of relevant solicitations for product and service contracts listed on Federal Business Opportunities (FBO), the centralized website where federal agencies are required to post procurements greater than $25,000. In 2010, ASE estimated a compliance rate of 46% in 2010, up from an estimate of 12% in 2008. Our work updates and expands on ASE’s 2010 analysis to gauge agency compliance with EEPP requirements.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

DOE OSTI2014

Far-infrared surface emissivity and climate

Presently, there are no global measurement constraints on the surface emissivity at wavelengths longer than 15 μm, even though this surface property in this far-IR region has a direct impact on the outgoing longwave radiation (OLR) and infrared cooling rates where the column precipitable water vapor (PWV) is less than 1 mm. Such dry conditions are common for high-altitude and high-latitude locations, with the potential for modeled climate to be impacted by uncertain surface characteristics. This paper explores the sensitivity of instantaneous OLR and cooling rates to changes in far-IR surface emissivity and how this unconstrained property impacts climate model projections. At high latitudes and altitudes, a 0.05 change in emissivity due to mineralogy and snow grain size can cause a 1.8–2.0 W m⁻² difference in the instantaneous clear-sky OLR. A variety of radiative transfer techniques have been used to model the far-IR spectral emissivities of surface types defined by the International Geosphere-Biosphere Program. Incorporating these far-IR surface emissivities into the Representative Concentration Pathway (RCP) 8.5 scenario of the Community Earth System Model leads to discernible changes in the spatial patterns of surface temperature, OLR, and frozen surface extent. The model results differ at high latitudes by as much as 2°K, 10 W m⁻², and 15%, respectively, after only 25 y of integration. The calculated difference in far-IR emissivity between ocean and sea ice of between 0.1 and 0.2, suggests the potential for a far-IR positive feedback for polar climate change.

58 GEOSCIENCES↗

DOE OSTI2022

An Integrated Risk Assessment Process of Safety-Related Digital I&C Systems in Nuclear Power Plants

Upgrading the existing analog instrumentation and control (I&C) systems to state-of-the-art digital I&C (DI&C) systems will greatly benefit existing light water reactors. However, the issue of software common cause failure (CCF) remains an obstacle in terms of qualification for digital technologies. Existing analyses of CCFs in I&C systems mainly focus on hardware failures. With the application and upgrading of new DI&C systems, design flaws could cause software CCFs to become a potential threat to plant safety, considering that most redundancy designs use similar digital platforms or software in their operating and application systems. With complex multilayer redundancy designs to meet the single failure criterion, these I&C safety systems are of particular concern in U.S. Nuclear Regulatory Commission licensing procedures. In Fiscal Year 2019, the Risk-Informed Systems Analysis (RISA) Pathway of the U.S. Department of Energy’s Light Water Reactor Sustainability Program initiated a project to develop a risk assessment strategy for delivering a strong technical basis to support effective, licensable, and secure DI&C technologies for digital upgrades and designs. An integrated risk assessment for the DI&C process was proposed for this strategy to identify potential key digital-induced failures, implement reliability analyses of related digital safety I&C systems, and evaluate the unanalyzed sequences introduced by these failures (particularly software CCFs) at the plant level. Here this paper summarizes these RISA efforts in the risk analysis of safety-related DI&C systems at Idaho National Laboratory.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗