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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Volume VII presents the chemical benchmarks for sediment: marine. Consult Volume I for information on the sources.
Volume VI presents the chemical benchmarks for sediment: fresh water. Consult Volume I for information on the sources.
Volume V presents the chemical benchmarks for surface water: general. The benchmarks here are applicable to both fresh water and marine or where no differentiation was made by the source. These values are not repeated in the fresh water and marine categories. Likewise, values listed in the fresh water and marine categories are not repeated in the generic categories. Consult Volume I for information on the sources.
Volume IV presents the chemical benchmarks for surface water: marine. Consult Volume I for information on the sources.
Volume III presents the chemical benchmarks for surface water: Fresh water. Consult Volume I for information on the sources.
Volume II presents the chemical benchmarks for soil. Consult Volume I for information on the sources.
We report in recent years, there has been an increased interest in 44Ti/44Sc generators as an onsite source of 44Sc for medical applications without needing a proximal cyclotron. The relatively short half-life (3.97 hours) and high positron branching ratio (94.3%) of 44Sc make it a viable candidate for positron emission tomography (PET) imaging. This review discusses current 44Ti/44Sc generator designs, focusing on their chemistry, drawbacks, post-elution processing, and relevant preclinical studies of the 44Sc for potential PET radiopharmaceuticals.
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Introduction: We developed a new method that drastically speeds up radiobiological Monte Carlo radiation-track-structure (MC-RTS) calculations on a cell-by-cell basis. Methods: The technique is based on random sampling and superposition of single-particle track (SPT) standard DNA damage (SDD) files from a “pre-calculated” data library, constructed using the RTS code TOPAS-nBio, with “time stamps” manually added to incorporate dose-rate effects. This time-stamped SDD file can then be input into MEDRAS, a mechanistic kinetic model that calculates various radiation-induced biological endpoints, such as DNA double-strand breaks (DSBs), misrepairs and chromosomal aberrations, and cell death. As a benchmark validation of the approach, we calculated the predicted energy-dependent DSB yield and the ratio of direct-to-total DNA damage, both of which agreed with published in vitro experimental data. We subsequently applied the method to perform a superfast cell-by-cell simulation of an experimental in vitro system consisting of neuroendocrine tumor cells uniformly incubated with 177 Lu. Results and discussion: The results for residual DSBs, both at 24 and 48 h post-irradiation, are in line with the published literature values. Our work serves as a proof-of-concept demonstration of the feasibility of a cost-effective “in silico clonogenic cell survival assay” for the computational design and development of radiopharmaceuticals and novel radiotherapy treatments more generally.
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Isotope power for space missions evaluated, noting candidate missions for isotope generators and the technological status of thermoelectric conversion
Radioactive nuclide activity levels and mass spectrometric measurements of rare gas isotopes in fragments of Bondoc mesosiderite
Tissue irradiated with protons and thermal/fast neutrons to study induced radioactive isotope production in astronauts
Experimental determination of cosmic radiation effects on tissue equivalent materials and humans
Activation analysis of fecal samples from Apollo 7, 8, 9, and 10 astronauts to determine effects of space flight on mass balance of various elements by human body
The proton-produced Na-22 content of samples of Surveyor 3 TV camera, surface sampler scoop, and other components was determined by nondestructive gamma ray spectrometry. The contributions of the nine most prominent solar flares to Na-22 production were calculated to be 18 dpm/kg. The observed activity in the Surveyor 3 samples was 62 + or - dpm/kg. This indicates a galactic proton contribution of about 44 dpm/kg, which adjusted for spallation of Al gives a value of 42 dpm/kg. This is compared to measurements of 88 dpm/kg in the Lost City meteorite which had an orbit extending to 2.35 AU, with a 4 pi bombardment as compared to the 2 pi bombardment of the samples on the lunar surface. The agreement between Na-22 production in Surveyor 3 and the Lost City meteorite offers evidence that the galactic cosmic ray flux is almost the same at 1 Au and at 2.35 AU.
Measurements were made of Na-22, Al-26, Mn-54, and Co-60 produced by cosmic rays in five samples of the Allende C3 meteorite and in one specimen of Murchison (C2); Sc-46, V-48, Cr-51, and Co-57 were also measured in several of these samples. Comparison of observed Allende Co-60 activities with calculated neutron-capture production rates yields a depth scale for Allende that appears unambiguous to about 30-cm depth. Using this scale, the production of Al-26 is constant to a depth in excess of 30 cm, Na-22 activity increases 30% from near the surface of Allende to 20- to 30-cm depth, and Mn-54 production increases 50% over the same depth range.