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Research on International Space Station - Building a Partnership for the Future

As its name implies, the International Space Station is a platform where the research programs of 16 partner nations are conducted. While each partner pursues its own research priorities, cooperation and coordination of the various national and agency research programs occurs at multiple levels, from strategic through tactical planning to experiment operations. Since 2000, a significant number of experiments have been carried out in the Russian ISS utilization program, which consists of the Russian national program of fundamental and applied research in 11 research areas and international cooperative programs and contract activities. The US research program began with simple payloads in 2000 and was significantly expanded with the addition of the US Laboratory module Destiny in 2001, and its outfitting with seven research racks to date. The Canadian Space Agency (CSA), the European Space Agency (ESA) and the Japan Aerospace Exploration Agency (JAXA) have made use of international cooperative arrangements with both the US and Russia to implement a variety of investigations in diverse research areas, and in the case of ESA included the flights of crewmembers to ISS as part of Soyuz Science Missions. In the future, ESA and JAXA will add their own research modules, Columbus and Kibo, respectively, to expand research capabilities both inside and outside ISS. In the aftermath of the Columbia accident and the temporary grounding of the Space Shuttle fleet, all ISS logistics have relied on Russian Progress and Sopz vehicles. The Russian national program has continued as before the Shuttle accident, as have international cooperative programs and contract activities, both during long-duration expeditions and visiting taxi missions. In several instances, Russian international cooperative activities with JAXA and ESA have also involved the use of US facilities and crewmembers in successful truly multilateral efforts. The US research program was rapidly refocused after the Shuttle accident to rely on greatly reduced upmass, and for the first time in the ISS program, US research hardware was launched on Progress vehicles and returned with crews on Soyuz spacecraft. It is hoped that these small but significant steps in international cooperation will lead to even greater endeavors once the remaining research modules are added to ISS.

Gindl, Heinz↗

Nuclear Safety [Vol. 30, No. 3, July-September 1989]

Nuclear Safety is a review journal that covers significant developments in the field of nuclear safety. Its scope includes the analysis and control of hazards associated with nuclear energy, operations involving fissionable materials, and the products of nuclear fission and their effects on the environment. Primary emphasis is on safety in reactor design, construction, and operation; however, the safety aspects of the entire fuel cycle, including fuel fabrication, spent-fuel processing, nuclear waste disposal, handling of radioisotopes, and environmental effects of these operations, are also treated. Table of Contents for this issue follows. GENERAL SAFETY CONSIDERATIONS: 325 Safety of Framatome Advanced Nuclear Steam Supply Systems Designs by J. A. Charles and D. Lange, 333 Book Review of Nuclear Accidents: Intervention Levels for the Protection of the Public by H. B. Piper; ACCIDENT ANALYSIS: 335 Living PRA Computer Systems by S. C. Dinsmore and H.-P. Balfanz, 343 Summary of ICAP Assessments of RELAP5/MOD2 by W. E. Driskell and R. G. Hanson; CONTROL AND INSTRUMENTATION: 352 Thermal Performance Monitoring System at Maanshan Nuclear Power Plant by H.-J. Chao, Y.-P. Lin, G.-H. Jou, L.-Y. Liao, and Y.-B. Chen; DESIGN FEATURES: 358 Warning Systems for Nuclear Power Plant Emergencies by J. H. Sorensen and D. S. Mileti; WASTE AND SPENT FUEL MANAGEMENT: 371 Activities Related to Waste Management Compiled by E G. Silver; OPERATING EXPERIENCES: 382 Steam Generator Tube Performance: Experience with Water-Cooled Nuclear Power Reactors During 1985 by O. S. Tatone and R. L. Tapping, 400 Systems Interaction Analyses: Concepts and Techniques (Part II) by M. D. Muhlheim and G. A. Murphy, 413 Reactor Shutdown Experience Compiled by J. W. Cletcher, 416 Operating U.S. Power Reactors Compiled by E G. Silver; RECENT DEVELOPMENTS: 440 General Administrative Activities Compiled by E G. Silver, 460 Reports, Standards, and Safety Guides by D. S. Queener, 466 Status of Power-Reactor Licensing Activities Compiled by E G. Silver, 470 Proposed Rule Changes as of Mar. 31, 1989; ANNOUNCEMENTS: 334 Proceedings Published, 351 CEC Seminar on Methods and Codes for Assessing the Off-Site Consequences of Nuclear Accidents, 357 Short Course on Multiphase Flow and Heat Transfer: Bases and Applications in A: The Nuclear Power Industry B: The Process Industries, 357 International Conference on Probabilistic Safety Assessment and Management, 478 International Topical Meeting on the Safety, Status, and Future of Non-Commercial Reactors and Irradiation Facilities, 475 The Authors.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Nuclear Safety [Vol. 29, No. 1, January-March 1988]

Nuclear Safety is a review journal that covers significant developments in the field of nuclear safety. Its scope includes the analysis and control of hazards associated with nuclear energy, operations involving fissionable materials, and the products of nuclear fission and their effects on the environment. Primary emphasis is on safety in reactor design, construction, and operation; however, the safety aspects of the entire fuel cycle, including fuel fabrication, spent-fuel processing, nuclear waste disposal, handling of radioisotopes, and environmental effects of these operations, are also treated. Table of Contents for this issue follows. THE CHERNOBYL ACCIDENT: 1 Core History and Nuclide Inventory of the Chernobyl Core at the Time of Accident by Gerald Kirchner and Cornelius C. Noack; GENERAL SAFETY CONSIDERATIONS: 6 Nonprescriptive Nuclear Safety Regulation: The Example of Loss of Offsite Power by M. W. Golay, V. P. Manno, and C. Vlahoplus, Jr., 20 Nuclear Power Safety Goals in Light of the Chernobyl Accident by C. Whipple and C. Starr; ACCIDENT ANALYSIS: 29 Containment Loads from Severe Accidents—U.S. Program by W. Kerr and M. K. Dey; PLANT SAFETY FEATURES: 36 Safety Characteristics of Modern High-Temperature Reactors: Focus on German Designs by W. Kröger, H. Nickel, and R. Schulten; ENVIRONMENTAL EFFECTS: 49 Radiation Hormesis and Nuclear Safety by C. C. Congdon; OPERATING EXPERIENCES: 58 Evaluation of Nonradiological Water Chemistry at Power Reactors by Harvey Zibulsky, James J. Kottan, Walter J. Pasciak, Mary Ann Castrogivanni, and Sujit Banerjee, 64 Reactor Shutdown Experience Compiled by J. W. Cletcher, 67 Operating U.S. Power Reactors Compiled by E. G. Silver; RECENT DEVELOPMENTS: 85 General Administrative Activities Compiled by E. G. Silver, 94 Reports, Standards, and Safety Guides by D. S. Queener, 100 Status of Power-Reactor Projects Undergoing Licensing Review Compiled by E. G. Silver, 103 Proposed Rule Changes as of Sept. 30, 1987; ANNOUNCEMENTS: 5 Northwestern University Short Course on Radiation Safety, 28 International Approach to Nuclear Safety (After Three-Mile Island and Chernobyl), 57 RPI Short Course on Modern Developments in Boiling Heat Transfer and Two-Phase Flow, 107 20th DOE/NRC Nuclear Air Cleaning Conference, 110 Third International Topical Meeting on Nuclear Power Plant Thermal Hydraulics and Operations, 108 The Authors, 111 Indexes to Nuclear Safety, Volume 28.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Nuclear Safety [Vol. 30, No. 1, January-March 1989]

Nuclear Safety is a review journal that covers significant developments in the field of nuclear safety. Its scope includes the analysis and control of hazards associated with nuclear energy, operations involving fissionable materials, and the products of nuclear fission and their effects on the environment. Primary emphasis is on safety in reactor design, construction, and operation; however, the safety aspects of the entire fuel cycle, including fuel fabrication, spent-fuel processing, nuclear waste disposal, handling of radioisotopes, and environmental effects of these operations, are also treated. Table of Contents for this issue follows. GENERAL SAFETY CONSIDERATIONS: 1 International Conference on Thermal Reactor Safety: NUCSAFE 88 by A. P. Malinauskas and J. G. Pruett; ACCIDENT ANALYSIS: 18 Chernobyl Today: State of Research by A. Yu. Gagarinskii; CONTROL AND INSTRUMENTATION: 23 Problems Associated with Routine In-Plant Radioactive Effluent Monitoring Systems at U.S. Light-Water Reactors by Barry G. Wahlig, David M. Walker, Mahmoud R. Ghavi, and John M. Palms; DESIGN FEATURES: 34 Twentieth DOE/NRC Nuclear Air-Cleaning Conference by R. R. Bellamy, D. W. Moeller, and M. W. First, 46 Design Options for the Core Support Structure for Liquid-Metal-Cooled Reactor Plants by J. P. Burelbach, W. J. Kann, J. G. Saiveau, and R. W. Seidensticker; ENVIRONMENTAL EFFECTS: 53 The Radiological Consequences of the Chernobyl Accident by L. V. Konstantinov and A. J. González; WASTE AND SPENT FUEL MANAGEMENT: 70 Activities Related to Waste Management Compiled by E. G. Silver; OPERATING EXPERIENCES: 80 Fuel Performance Annual Report for 1986 by W. J. Bailey, 103 Safety Considerations Related to 12-Hour Shift Schedules by S. Gould, 105 Reactor Shutdown Experience Compiled by J. W. Cletcher, 108 Operating U.S. Power Reactors Compiled by E. G. Silver; RECENT DEVELOPMENTS: 130 General Administrative Activities Compiled by E. G. Silver, 140 Reports, Standards, and Safety Guides by D. S. Queener, 145 Status of Power-Reactor Licensing Activities Compiled by E. G. Silver, 153 Proposed Rule Changes as of Sept. 30, 1988; ANNOUNCEMENTS: 69 Northwestern University Short Course on Radiation Safety, 79 International Seminar on Fission Product Transport Processes in Reactor Accidents, 129 Harvard School of Public Health Offers Short Courses, 152 MIT Offers Summer Short Courses on Reactor Safety and Nodal Analysis, 152 Seminar on Use of PCs in Probabilistic Safety Analysis, 157 The Authors, 160 Indexes to Nuclear Safety, Volume 29.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Exploring Advanced Computational Tools and Techniques with Artificial Intelligence and Machine Learning in Operating Nuclear Plants

This report presents the project Idaho National Laboratory conducted for Nuclear Regulatory Commission to explore the advanced computational tools and techniques, such as artificial intelligence (AI) and machine learning (ML), for operating nuclear plants. The report reviews the nuclear data sources, with the focus on the operating experience data, that could be applied by advanced computational tools and techniques. Plant-specific and generic (national and international) data from different sources are described. The report describes the relationships between statistics and AI/ML and then introduces the most widely used AI/ML algorithms in both supervised and unsupervised learning. The report reviews the recent applications of advanced computational tools and techniques in various fields of nuclear industry, such as reactor system design and analysis, plant operation and maintenance, and nuclear safety and risk analysis. Finally, the report presents the insights from the project on the potential applicability of AI/ML techniques in improving advanced computational capabilities, how the advanced tools and techniques could contribute to the understanding of safety and risk, and what information would be needed to provide meaningful insights to decision makers. The report also documents an NRC survey on the current state of commercial nuclear power operations relative to the use of AI and ML tools as well as the role of AI/ML tools in nuclear power operations was published by the NRC as in FRN NRC-2021-0048 in April 2021. A summary of the survey including the survey questions, survey participants, survey responses, and the conclusions and insights derived from the survey is provided in the report. Finally, the report investigates potential applications of using AI/ML in operating NPPs and advanced reactors (both advanced LWRs and advanced NLWRs) to improve nuclear plant safety and efficiency. Three main application fields are defined and discussed: (1) plant safety and security assessments; (2) plant degradation modeling, fault and accident diagnosis and prognosis; and (3) plant operation and maintenance efficiency improvement.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Cislunar Autonomous Positioning System Technology Operations and Navigation Experiment (CAPSTONE)

NASA has partnered with Advanced Space to develop and build the Cislunar Autonomous Positioning System Technology Operations and Navigation Experiment (CAPSTONE) mission which will serve as a pathfinder for Near Rectilinear Halo Orbit (NHRO) operations around the Moon. The NHRO, (Perilune = 3,200 km; Apolune = 70,000 km) will be the intended orbit for the NASA’s Artemis Gateway lunar orbital platform. The CAPSTONE mission will validate simulations and confirm operational planning for Gateway while also validating performance of navigation and station-keeping requirements for the Power and Propulsion Element. Thus, this mission will provide operational experience to NASA, commercial, and international missions for operations in a demanding orbital regime. The baseline for CAPSTONE is to fly a 12U cubesat developed, integrated, and tested by Tyvak Nanosatellite Systems carrying a payload communications system capable of cross-link ranging with the Lunar Reconnaissance Orbiter (LRO), a dedicated payload flight computer for software demonstration, and a camera. The launch, coordinated by NASA Launch Services Program, will be provided by a Rocket Lab launch vehicle utilizing their new Proton upper stage to deploy the CAPSTONE spacecraft into the lunar orbit. The CAPSTONE mission is targeting a launch no earlier than September 23, 2021. Upon launch, the spacecraft will traverse a highly efficient transfer taking approximately three months to enter a primary demonstration phase in an NRHO for six months followed by a twelve month technology enhancement operations phase. The CAPSTONE Project is lead by Advanced Space, LLC of Boulder Colorado. Spacecraft development and mission operations will be conducted by Tyvak Nanosatellite Systems of Irvine, California. Noted objectives for the CAPSTONE mission will be to demonstrate the accessibility of NHROs, validate key operational concepts in the NHRO environment, lay a foundation for commercial support of future lunar operations and accelerate the availability of peer-to-peer navigation capabilities provided by the Cislunar Autonomous Positioning System (CAPS). The CAPSTONE mission is funded through NASA's Small Spacecraft Technology Program (SSTP), which is one of several programs in NASA’s Space Technology Mission Directorate. SSTP is chartered to develop and demonstrate technologies to enhance and expand the capabilities of small spacecraft with a particular focus on enabling new mission architectures through the use of small spacecraft, expanding the reach of small spacecraft to new destinations, and augmenting future missions with supporting small spacecraft. The launch for the CAPSTONE Mission is provided by Human Exploration & Operations Missions Directorate Advanced Exploration Systems Division. Coordination and Acquisition of the Launch is managed by NASA’s Launch Services Program. The CAPSTONE Mission and project status will be presented.

CAPSTONE↗

Operation Heli-STAR - Atlanta Communications Experiment (ACE)

Operation Heli-STAR (Helicopter Short-Haul Transportation and Aviation Research) was established and operated in Atlanta, Georgia, during the period of the 1996 Centennial Olympic Games. Heli-STAR had three major thrusts: (1) the establishment and operation of a helicopter-based cargo transportation system, (2) the management of low-altitude air traffic in the airspace of an urban area, and (3) the collection and analysis of research and development data associated with items 1 and 2. Heli-STAR was a cooperative industry/government program that included parcel package shippers and couriers in the Atlanta area, the helicopter industry, aviation electronics manufacturers, the Federal Aviation Administration (FAA), the National Aeronautics and Space Administration (NASA), and support contractors. Several detailed reports have been produced as a result of Operation Heli-STAR. These include four reports on acoustic measurements and associated analyses, and reports on the Heli-STAR tracking data including the data processing and retrieval system, the Heli-STAR cargo simulation, and the community response system. In addition, NASA's Advanced General Aviation Transport Experiments (AGATE) program has produced a report describing the Atlanta Communications Experiment (ACE) which produced the avionics and ground equipment using automatic dependent surveillance-broadcast (ADS-B) technology. This latter report is restricted to organizations belonging to NASA's AGATE industry consortium. A complete list of these reports is shown on the following page.

Source record↗

Cislunar Autonomous Positioning System Technology Operations and Navigation Experiment (CAPSTONE) Mission

NASA has partnered with Advanced Space to develop and build the Cislunar Autonomous Positioning System Technology Operations and Navigation Experiment (CAPSTONE) mission which will serve as a pathfinder for Near Rectilinear Halo Orbit (NHRO) operations around the Moon. The NHRO, (Perilune = 3,200 km; Apolune = 70,000 km) will be the intended orbit for the NASA’s Artemis Gateway lunar orbital platform. The CAPSTONE mission will validate simulations and confirm operational planning for Gateway while also validating performance of navigation and station-keeping requirements for the Power and Propulsion Element. Thus, this mission will provide operational experience to NASA, commercial, and international missions for operations in a demanding orbital regime. The baseline for CAPSTONE is to fly a 12U cubesat developed, integrated, and tested by Tyvak Nanosatellite Systems carrying a payload communications system capable of cross-link ranging with the Lunar Reconnaissance Orbiter (LRO), a dedicated payload flight computer for software demonstration, and a camera. The launch, coordinated by NASA Launch Services Program, will be provided by a Rocket Lab launch vehicle utilizing their new Proton upper stage to deploy the CAPSTONE spacecraft into the lunar orbit. The CAPSTONE mission is targeting a launch no earlier than September 23, 2021. Upon launch, the spacecraft will traverse a highly efficient transfer taking approximately three months to enter a primary demonstration phase in an NRHO for six months followed by a twelve month technology enhancement operations phase. The CAPSTONE Project is lead by Advanced Space, LLC of Boulder Colorado. Spacecraft development and mission operations will be conducted by Tyvak Nanosatellite Systems of Irvine, California. Noted objectives for the CAPSTONE mission will be to demonstrate the accessibility of NHROs, validate key operational concepts in the NHRO environment, lay a foundation for commercial support of future lunar operations and accelerate the availability of peer-to-peer navigation capabilities provided by the Cislunar Autonomous Positioning System (CAPS). The CAPSTONE mission is funded through NASA's Small Spacecraft Technology Program (SSTP), which is one of several programs in NASA’s Space Technology Mission Directorate. SSTP is chartered to develop and demonstrate technologies to enhance and expand the capabilities of small spacecraft with a particular focus on enabling new mission architectures through the use of small spacecraft, expanding the reach of small spacecraft to new destinations, and augmenting future missions with supporting small spacecraft. The launch for the CAPSTONE Mission is provided by Human Exploration & Operations Missions Directorate Advanced Exploration Systems Division. Coordination and Acquisition of the Launch is managed by NASA’s Launch Services Program. The CAPSTONE Mission and project status will be presented.

CAPSTONE↗

Advanced Communications Technology Satellite (ACTS) Used for Inclined Orbit Operations

The Advanced Communications Technology Satellite (ACTS) is operated by the NASA Glenn Research Center at Lewis Field 24 hours a day, 7 days a week. ACTS, which was launched in September 1993, is in its 7th year of operations, far exceeding the system s planned 2 years of operations and 4 years of designed mission life. After 5 successful years of operating as a geostationary satellite, the spacecraft s North-South stationkeeping was discontinued in August 1998. The system is now operating in an inclined orbit that increases at a rate of 0.8 /yr. With only scarce fuel remaining, operating in this mode extends the usage of the still totally functional payload. Although tracking systems are now needed on the experimenter Earth stations, experiment operations have continued with very little disruption. This is the only known geosynchronous Ka-band (30/20 GHz) spot-beam satellite operating in an inclined orbit. The project began its transition from geostationary operations to inclined operations in August 1998. This did not interrupt operations and was transparent to the experimenters on the system. For the space segment, new daily procedures were implemented to maintain the pointing of the system s narrow 0.3 spot beams while the spacecraft drifts in the North-South direction. For the ground segment, modifications were designed, developed, and fielded for the three classes of experimenter Earth stations. With the next generation of commercial satellite systems still being developed, ACTS remains the only operational testbed for Ka-band geosynchronous satellite communications over the Western hemisphere. Since inclined orbit operations began, the ACTS experiments program has supported 43 investigations by industry, Government, and academic organizations, as well as four demonstrations. The project s goals for inclined-orbit operations now reflect a narrower focus in the types of experiments that will be done. In these days of "faster, better, cheaper," NASA is seeking to gain greater relevance to the agency s mission from these experiments. One area that is of much interest both to NASA and the commercial world is the investigation of protocol issues related to the interoperability of satellites with terrestrial networks, such as Transmission Control Protocol/Internet Protocol (TCP/IP) and Asynchronous Transfer Mode (ATM) over wideband satellites. Other experiment areas of interest are supporting the U.S. Government and NASA as they begin using commercial space assets to meet their communications needs, evaluating issues related to operating a spot-beam satellite in inclined orbit, and evaluating new Ka-band hardware that requires a satellite link. ACTS is now in its last year of operations. Operations are planned through June 2000, when after 81 months of operations, this very successful spacecraft will be superorbited and made inert.

Bauer, Robert A.↗

Solar parabolic dish thermal power systems - Technology and applications

Activities of two projects at JPL in support of DOE's Small Power Systems Program are reported. These two projects are the Point-Focusing Distributed Receiver (PFDR) Technology Project and the Point-Focusing Thermal and Electric Applications (PFTEA) Project. The PFDR Technology Project's major activity is developing the technology of solar concentrators, receivers and power conversion subsystems suitable for parabolic dish or point-focusing distributed receiver power systems. Other PFDR activities include system integration and cost estimation under mass production, as well as the testing of the hardware. The PFTEA Project's first major activity is applications analysis, that is seeking ways to introduce PFDR systems into appropriate user sectors. The second activity is systems engineering and development wherein power plant systems are analyzed for specific applications. The third activity is the installation of a series of engineering experiments in various user environments to obtain actual operating experience

Lucas, J. W.↗

The Applied Meteorology Unit: Nineteen Years Successfully Transitioning Research into Operations for America's Space Program

The Applied Meteorology Unit (AMU) provides technology transition and technique development to improve operational weather support to the Space Shuttle and the entire American space program. The AMU is funded and managed by NASA and operated by a contractor that provides five meteorologists with a diverse mix of advanced degrees, operational experience, and associated skills including data processing, statistics, and the development of graphical user interfaces. The AMU's primary customers are the U.S. Air Force 45th Weather Squadron at Patrick Air Force Base, the National Weather Service Spaceflight Meteorology Group at NASA Johnson Space Center, and the National Weather Service Melbourne FL Forecast Office. The AMU has transitioned research into operations for nineteen years and worked on a wide range of topics, including new forecasting techniques for lightning probability, synoptic peak winds,.convective winds, and summer severe weather; satellite tools to predict anvil cloud trajectories and evaluate camera line of sight for Space Shuttle launch; optimized radar scan strategies; evaluated and implemented local numerical models; evaluated weather sensors; and many more. The AMU has completed 113 projects with 5 more scheduled to be completed by the end of 2010. During this rich history, the AMU and its customers have learned many lessons on how to effectively transition research into operations. Some of these lessons learned include collocating with the operational customer and periodically visiting geographically separated customers, operator submitted projects, consensus tasking process, use of operator primary advocates for each project, customer AMU liaisons with experience in both operations and research, flexibility in adapting the project plan based on lessons learned during the project, and incorporating training and other transition assistance into the project plans. Operator involvement has been critical to the AMU's remarkable success and many awards from NASA, the National Weather Association, and two citations from the Navy's Center of Excellence for Best Manufacturing Practices. This paper will present the AMU's proven methods and explain how they may be applied by other organizations to effectively transition research into operations.

Madura, John T.↗

Near-Earth Object Exploration and Marco Polo-R

A major goal for NASA's human spaceflight program is to send astronauts to near-Earth asteroids (NEAs) in the coming decades. Missions to NEAs would undoubtedly provide a great deal of technical and engineering data on spacecraft operations for future human space exploration while conducting in-depth scientific examinations of these primitive objects. However, prior to sending human explorers to NEAs, robotic investigations of these bodies would be required in order to maximize operational efficiency and reduce mission risk. These precursor missions to NEAs would fill crucial strategic knowledge gaps concerning their physical characteristics that are relevant for human exploration of these relatively unknown destinations. Therefore robotic investigations of NEAs, such as ESA's Marco Polo-R sample return mission to 2008 EV5, would allow NASA and its international partners to gain critical operational experience in performing complex tasks (e.g., close proximity operations, surface sample collection, etc.) under microgravity conditions at or near the surface of a potential human destination. This would provide an important synergy between the worldwide Science and Exploration communities, which will be crucial for development of future international deep space exploration architectures and has potential benefits for future exploration of other destinations beyond low-Earth orbit.

Abell, Paul↗

Flight Hardware Fabricated for Combustion Science in Space

NASA Glenn Research Center s Telescience Support Center (TSC) allows researchers on Earth to operate experiments onboard the International Space Station (ISS) and the space shuttles. NASA s continuing investment in the required software, systems, and networks provides distributed ISS ground operations that enable payload developers and scientists to monitor and control their experiments from the Glenn TSC. The quality of scientific and engineering data is enhanced while the long-term operational costs of experiments are reduced because principal investigators and engineering teams can operate their payloads from their home institutions.

OMalley, Terence F.↗

The Biotechnology Facility for International Space Station

The primary mission of the Cellular Biotechnology Program is to advance microgravity as a tool in basic and applied cell biology. The microgravity environment can be used to study fundamental principles of cell biology and to achieve specific applications such as tissue engineering. The Biotechnology Facility (BTF) will provide a state-of-the-art facility to perform cellular biotechnology research onboard the International Space Station (ISS). The BTF will support continuous operation, which will allow performance of long-duration experiments and will significantly increase the on-orbit science throughput. With the BTF, dedicated ground support, and a community of investigators, the goals of the Cellular Biotechnology Program at Johnson Space Center are to: Support approximately 400 typical investigator experiments during the nominal design life of BTF (10 years). Support a steady increase in investigations per year, starting with stationary bioreactor experiments and adding rotating bioreactor experiments at a later date. Support at least 80% of all new cellular biotechnology investigations selected through the NASA Research Announcement (NRA) process. Modular components - to allow sequential and continuous experiment operations without cross-contamination Increased cold storage capability (+4 C, -80 C, -180 C). Storage of frozen cell culture inoculum - to allow sequential investigations. Storage of post-experiment samples - for return of high quality samples. Increased number of cell cultures per investigation, with replicates - to provide sufficient number of samples for data analysis and publication of results in peer-reviewed scientific journals.

Goodwin, Thomas↗

The Nimbus-4 backscatter ultraviolet (BUV) atmospheric ozone experiment two years operation

The Backscatter Ultraviolet (BUV) experiment aboard the Nimbus-4 satellite is discussed. This double monochromator experiment measures ultraviolet terrestrial radiance at 12 discrete wavelengths between 2550 A and 3400 A. Approximately 100 scans covering a 230 kilometer square are made between terminator crossings on the daylight side of the earth. A colinear photometer channel with the same field of view is used to derive the Lambert reflectivity of the lower boundary of the scattering atmosphere. The extraterrestrial solar irradiance is measured at the northern terminator. The instrument has currently produced almost three years of nearly continuous data which are being used to infer the high-level ozone distribution and total ozone on a global basis. The high-level ozone data have been verified by independent coincident rocket ozone soundings, and the total ozone values show good agreement with Dobson spectrophotometer determinations as well as those made with the Infrared Interferometer Spectrometer also on Nimbus-4.

Heath, D. F.↗

Orbit determination support of the Ocean Topography Experiment (TOPEX)/Poseidon operational orbit

The Ocean Topography Experiment (TOPEX/Poseidon) mission is designed to determine the topography of the Earth's sea surface over a 3-year period, beginning shortly after launch in July 1992. TOPEX/Poseidon is a joint venture between the United States National Aeronautics and Space Administration (NASA) and the French Centre Nationale d'Etudes Spatiales. The Jet Propulsion Laboratory is NASA's TOPEX/Poseidon project center. The Tracking and Data Relay Satellite System (TDRSS) will nominally be used to support the day-to-day orbit determination aspects of the mission. Due to its extensive experience with TDRSS tracking data, the NASA Goddard Space Flight Center (GSFC) Flight Dynamics Facility (FDF) will receive and process TDRSS observational data. To fulfill the scientific goals of the mission, it is necessary to achieve and maintain a very precise orbit. The most stringent accuracy requirements are associated with planning and evaluating orbit maneuvers, which will place the spacecraft in its mission orbit and maintain the required ground track. To determine if the FDF can meet the TOPEX/Poseidon maneuver accuracy requirements, covariance analysis was undertaken with the Orbit Determination Error Analysis System (ODEAS). The covariance analysis addressed many aspects of TOPEX/Poseidon orbit determination, including arc length, force models, and other processing options. The most recent analysis has focused on determining the size of the geopotential field necessary to meet the maneuver support requirements. Analysis was undertaken with the full 50 x 50 Goddard Earth Model (GEM) T3 field as well as smaller representations of this model.

Schanzle, A. F.↗

Enhancing Biomass Productivity by Forecast‐Informed Pond Operations

ABSTRACT Microalgal cultivation for biofuels and proteins holds significant promise but faces challenges in achieving economically viable biomass productivity under variable environmental conditions. This study introduces a forecast‐informed pond operation (FIPO) system that uses numerical weather prediction (NWP) ensemble forecasts and the biomass assessment tool (BAT) to optimize daily dilution rates for enhanced biomass production. In contrast to the current practice, where fixed dilution rates are based on operator experience, the FIPO system determines the optimal dilution rate based on future weather forecasts and biomass growth conditions. Our experiments validate the effectiveness of FIPO in both short‐ and long‐term growth scenarios. In short‐term experiments, FIPO increased biomass production by 21.3% compared to batch growth and 7.4% over fixed dilution (60% every 3 days) operations. The NWP forecast‐informed operations achieved biomass production nearly identical to that using perfect weather forecasts, highlighting the accuracy of current NWP forecasts for guiding pond operations. In long‐term experiments, FIPO resulted in biomass production increases of 13.3% and 17.8% compared to two fixed dilution rates (60% every 3 days and 20% daily). These findings underscore the viability of using NWP forecasts to optimize microalgal cultivation systems. By adjusting daily dilution rates in response to forecasted weather, operators can achieve higher biomass yields and mitigate risks associated with environmental variability. This study provides a foundation for future research and practical applications in commercial‐scale microalgal production.

Yan, Hongxiang [Energy and Environment Directorate↗

A Comprehensive Characterization of Microorganisms and Allergens in Spacecraft Environment

The determination of risk from infectious disease during long-duration missions is composed of several factors including the concentration and the characteristics of the infectious agent. Thus, a thorough knowledge of the microorganisms aboard spacecraft is essential in mitigating infectious disease risk to the crew. While stringent steps are taken to minimize the transfer of potential pathogens to spacecraft, several medically significant organisms have been isolated from both the Mir and International Space Station (ISS). Historically, the method for isolation and identification of microorganisms from spacecraft environmental samples depended upon their growth on culture media. Unfortunately, only a fraction of the organisms may grow on a culture medium, potentially omitting those microorganisms whose nutritional and physical requirements for growth are not met. Thus, several pathogens may not have been detected, such as Legionella pneumophila, the etiological agent of Legionnaire s disease. We hypothesize that environmental analysis using non-culture-based technologies will reveal microorganisms, allergens, and microbial toxins not previously reported in spacecraft, allowing for a more complete health assessment. The development of techniques for this flight experiment, operationally named SWAB, has already provided advances in NASA laboratory processes and beneficial information toward human health risk assessment. The translation of 16S ribosomal DNA sequencing for the identification of bacteria from the SWAB experiment to nominal operations has increased bacterial speciation of environmental isolates from previous flights three fold compared to previous conventional methodology. The incorporation of molecular-based DNA fingerprinting using repetitive sequence-based polymerase chain reaction (rep-PCR) into the capabilities of the laboratory has provided a methodology to track microorganisms between crewmembers and their environment. Both 16S ribosomal DNA identification and bacterial fingerprinting have improved NASA s capability to better understand spacecraft environments and determine the source of contamination events. Preflight sampling has been completed for air, surface, and water samples. In-flight sample collection has been completed for a total of 8 air and surface sample collection sessions. In-flight hardware has performed well and the surface sampling device received positive feedback from the crew for its ease of use. While processing and analysis continue for these samples, early results have begun to provide information on the spacecraft environment. Using a method called Denaturing Gradient Gel Electrophoresis (DGGE), several air and samples were evaluated to determine the types of organisms that were present. Using only molecular techniques, DGGE does not depend on any microbial growth on culture media, allowing a more comprehensive assessment of the spacecraft interior. Preliminary results have identified several microorganisms that would not have been isolated using current technology, though none of these organisms would be considered medically significant. Interestingly, the isolation of Gram negative organisms is greater using DGGE than conventional media based isolation. The cause of this finding is unclear, though it may be the result of the technique s ability to isolate both viable and non-viable bacteria. The next phase of the SWAB sample analysis is the use of quantitative polymerase chain reaction (QPCR) to look for specific medically significant organisms. While not as broad as DGGE, QPCR is much more sensitive and may reveal findings that were not seen during the initial evaluation. Together, this information will lead toward an accurate microbial risk assessment to help set flight requirements to protect the safety, health, and performance of the crew.

Castro, V.A.↗