Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-n
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Chen, Xuejun↗
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Results for “maturation”
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Zinc Dynamics during Drosophila Oocyte Maturation and Egg Activation
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59 BASIC BIOLOGICAL SCIENCES↗
Role of ammonia-lyases in the synthesis of the dithiomethylamine ligand during [FeFe]-hydrogenase maturation
Not Available
Pagnier, Adrien (ORCID:0000000219512415)↗
Organic and hybrid thermoelectrics are maturing, but not yet a market
Not Available
Urban, Jeffrey J.↗
Effects of maturity and temperature on soot density and specific heat
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Michelsen, Hope A. (ORCID:0000000158026615)↗
Interannual variations and trends of gross primary production and transpiration of four mature deciduous broadleaf forest sites during 2000–2020
Not provided.
Environmental Sciences & Ecology↗
Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation
SARS-CoV-2 is a betacoronavirus virus responsible for the COVID-19 pandemic. Here, we determine the X-ray crystal structure of a potent neutralizing monoclonal antibody, CV30, isolated from a patient infected with SARS-CoV-2, in complex with the receptor binding domain. The structure reveals that CV30 binds to an epitope that overlaps with the human ACE2 receptor binding motif providing a structural basis for its neutralization. CV30 also induces shedding of the S1 subunit, indicating an additional mechanism of neutralization. A germline reversion of CV30 results in a substantial reduction in both binding affinity and neutralization potential indicating the minimal somatic mutation is needed for potently neutralizing antibodies against SARS-CoV-2.
59 BASIC BIOLOGICAL SCIENCES↗
A conformational role for NifW in the maturation of molybdenum nitrogenase P-cluster
Upon binding of NifW, a subtle conformation change occurs in NifD 2 K 2 , decreasing the distance between the two [4Fe:4S] clusters precursors of the P-cluster in nitrogenase.
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
Carbon capture from corn stover ethanol production via mature consolidated bioprocessing enables large negative biorefinery GHG emissions and fossil fuel-competitive economics
Potential to capture 70% of feedstock carbon while >50% of feedstock lower heating value is converted to biofuel and coproducts.
Kubis, Matthew R.↗
Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myastheni
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Fichtner, Miriam L.↗