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At least 289 records · Page 16

Generation of radioisotopes for medical applications using high-repetition, high-intensity lasers

We used the PW high-repetition laser facility VEGA-3 at Centro de Láseres Pulsados in Salamanca, with the goal of studying the generation of radioisotopes using laser-driven proton beams. Various types of targets have been irradiated, including in particular several targets containing boron to generate α-particles through the hydrogen–boron fusion reaction. We have successfully identified γ-ray lines from several radioisotopes created by irradiation using laser-generated α-particles or protons including 43 Sc, 44 Sc, 48 Sc, 7 Be, 11 C and 18 F. We show that radioisotope generation can be used as a diagnostic tool to evaluate α-particle generation in laser-driven proton–boron fusion experiments. We also show the production of 11 C radioisotopes, ≈ 6 × 10 6 , and of 44 Sc radioisotopes, ≈ 5 × 10 4 per laser shot. This result can open the way to develop laser-driven radiation sources of radioisotopes for medical applications.

gamma ray spectroscopy↗

Six-photon resonant scattering of collinear laser pulses in plasma

To achieve the highest possible laser intensities with the least laser energy, shorter-wavelengths lasers are advantaged if they can be focused to spots of a few laser wavelengths and durations of several laser periods. However, the top laser pulse energies available nowadays are megajoules at near-optical wavelengths and millijoules at shorter wavelengths. Thus, to produce the highest laser intensities, what is required is an efficient spectral transfer of the huge near-optical energies to shorter wavelengths. It is proposed here that the desired spectral transfer could occur via resonant photon interactions associated with nonlinearity of mildly relativistic motions of plasma electrons in intense laser fields, specifically via the six-photon resonant scattering of collinear laser pulses in plasma. As a result, the six-photon interaction can, in fact, be the dominant resonant photon interaction to achieve collinear frequency up-conversion.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Silicon production in an aerosol reactor

An aerosol reactor for the growth of large silicon particles by silane pyrolysis was shown to demonstrate the following properties: (1) generate seed particles by pyrolysis of a small amount of silane; (2) mix seed aerosol with primary silane flow, limiting number concentration such that the amount of silane is sufficient to grow the desired size of particles from the seed; and (3) react the silane at a rate which is controlled such that the seed particles scavenge the condensible vapors rapidly enough to inhibit further nucleation.

Wu, J. J.↗

Chromosome aberrations in human lymphocytes induced by 250 MeV protons: effects of dose, dose rate and shielding

Although the space radiation environment consists predominantly of energetic protons, astronauts inside a spacecraft are chronically exposed to both primary particles as well as secondary particles that are generated when the primary particles penetrate the spacecraft shielding. Secondary neutrons and secondary charged particles can have an LET value that is greater than the primary protons and, therefore, produce a higher relative biological effectiveness (RBE). Using the accelerator facility at Loma Linda University, we exposed human lymphocytes in vitro to 250 MeV protons with doses ranging from 0 to 60 cGy at three different dose rates: a low dose rate of 7.5 cGy/h, an intermediate dose rate of 30 cGy/h and a high dose rate of 70 cGy/min. The effect of 15 g/cm2 aluminum shielding on the induction of chromosome aberrations was investigated for each dose rate. After exposure, lymphocytes were incubated in growth medium containing phytohemagglutinin (PHA) and chromosome spreads were collected using a chemical-induced premature chromosome condensation (PCC) technique. Aberrations were analyzed using the fluorescence in situ hybridization (FISH) technique with three different colored chromosome-painting probes. The frequency of reciprocal and complex-type chromosome exchanges were compared in shielded and unshielded samples. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Non-NASA Center↗

Chromosome Aberration in Human Blood Lymphocytes Exposed to Energetic Protons

During space flight, astronauts are exposed to a space radiation consisting of high-energy protons, high charge and energy (HZE) nuclei, as well as secondary particles that are generated when the primary particles penetrate the spacecraft shielding. Secondary particles have a higher LET value than primary protons and therefore expected to have a higher relative biological effectiveness (RBE). To investigate this theory, we exposed human peripheral blood lymphocytes to protons with energies of 250 MeV, 800MeV, 2 GeV, or 2.5 GeV. LET values for these protons ranged from 0.4 to 0.2 keV/micrometer. and doses ranged from 0.2 to 3 Gy. Over this energy the probability of nuclear reaction leading to secondary radiation, and the multiplicity of reaction produces such as neutrons and mesons increases substantially. The effect of aluminum and polyethylene shielding was also assessed using the 2 GeV and 2.5GeV proton beams. After exposure lymphocytes were stimulated to divide and chromosomes were collected from cells in the first G2 and metaphase cell cycle after exposure using a chemical induced premature chromosome condensation (PCC) technique. Dose response data for chromosome damage was analyzed using the fluorescence in situ hybridization (FISH) chromosome painting technique. Selected samples were also analyzed with multicolor FISH (mFISH) and multicolor banding FISH (mBAND) techniques. Data indicates that the dose response for simple-type exchanges is similar for proton and gamma exposure, whereas protons induce higher yields of complex exchanges that are LET dependent. RBE values will be presented for each proton energy, and the effects of shielding and possible cytogenetic signatures of proton exposure will be discussed.

Hada, M.↗

Particle-impact noise detector (PIND)

Package, in page assembly, is subjected to low-frequency vibration, and noise generated by particle impacts is picked up by transducer. Test procedure calls for three transverse shocks to be applied to page to dislodge any trapped particles.

Barr, R. J.↗

Particle Track Classification Using Quantum Associative Memory (Final Technical Report)

This project explored the use of quantum-assisted algorithms for pattern matching in sub-atomic physics experiments. Pattern matching algorithms are commonly employed to prune data of random noise and to help discriminate between signals generated by particle tracks of interest and signals generated by background events. The quantum-assisted algorithms explored in this project were based on an Ising formulation of quantum associative model (QAMM) recall and quantum content-addressable memory (QCAM) recall. The recall is performed by comparing a probe pattern with those stored in a library of patterns encoded in the QAMM/QCAM model. The classification accuracy of QAMM and QCAM recall was determined as a function of detector resolution, noise, and efficiency and pattern density, where pattern density is defined as the ratio of the number of reference signal patterns encoded in the library to each pattern’s length. We found that QAMM achieved high classification accuracy when applied to datasets with low pattern density. QCAM achieved high classification accuracy for datasets with high pattern density and was found to be more robust to detector noise. The project methodology and results are described in detail in our arXiv preprint (arXiv:2011.11848) . This project was conducted by scientists at the Johns Hopkins University Applied Physics Laboratory and Oak Ridge National Laboratory from August 2018 to August 2020 and was supported by DOE grant DE-SC0019497.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Water-based Liquid Scintillator detector as a new technology testbed for neutrino studies in Turkey

This study investigates the deployment of a medium-scale neutrino detector near Turkey's rst nuclear power plant, the Akkuyu Nuclear Power Plant. The aim of this detector is to become a modular testbed for new technologies in the elds of new detection media and innovative photosensors. Such technologies include Water-based Liquid Scintillator (WbLS), Large Area Picosecond Photo- Detectors (LAPPDs), dichroic Winston cones, and large area silicon photomul- tiplier modules. Here, the detector could be used for instantaneous monitoring of the Akkuyu Nuclear Power Plant via its antineutrino ux. In addition to its physics and technological goals, it would be an invaluable opportunity for the nuclear and particle physics community in Turkey to play a role in the development of next generation of particle detectors in the eld of neutrino physics.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Flux Creep in a Bi-2212 Rutherford Cable for Particle Accelerator Applications

Bi-2212 superconducting cables are being considered for use in the high field magnets needed for the next generation of particle accelerators. Magnetization in these cables and the decay of that magnetization lead to field error and field-error drift, respectively, which need to be compensated. To study this, a segment of the winding pack was extracted from a racetrack coil made from Bi-2212 Rutherford cable. Using a Hall probe measurement technique, we measured the response of the cable's magnetization and its magnetization decay to changes in the applied magnetic field. The effect of adjustments to the cycling of the magnetic field was studied, intended to simulate the preinjection cycles of an accelerator magnet. Three M vs. H loops were constructed by sweeping the magnetic field applied to the sample from 0 to 2.5 T, then to a preinjection field 'x' (where x = 0, 0.25, 0.75 T), and finally up to 1 T. The applied field was then held at 1 T for 1500 s, and the magnetization decay was measured. Finally, the decay was found to vary from 8% to 14% after 1500 s, depending on the preinjection field cycle.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Mitigation of Polystyrene Microsphere Surface Contamination for Wind Tunnel Applications

Polystyrene latex (PSL) microspheres have been utilized as seed material for flow visualization in wind tunnels. However, PSL microspheres have been observed to strongly adhere to wind tunnel and model surfaces. Surface contamination on the cleaning screens that remove vorticity and provide laminar flow in the test section, is particularly problematic. Agglomeration of particles on these screens cause constriction of the airflow through the screen resulting in inconsistent airflow properties in the test section. The adhesion mechanism of PSL microspheres to wind tunnel screens and 316 stainless steel flat plates, were evaluated in a contamination apparatus where small sections of screen material were exposed to PSL-seeded airflow. Using a design of experiments (DOE) methodology airflow seeding parameters were changed to evaluate how these modifications affected the degree of surface contamination. The solution composition, comprised of ethanol and water, was determined to be the most significant factor in particle adhesion. Utilizing image analysis software, data were collected from the contaminated surfaces and incorporated to generate predictive particle contamination models. A relationship was identified between the solvent evaporation rate, and the morphology and magnitude of PSL contaminants on the test surfaces. This analysis can be extended to other solvent mixtures to provide insight into simultaneously improving wind tunnel testing capabilities while diminishing facility contamination.

Wohl, Christopher J.↗

Experimental Setup for the Laboratory Investigation of Micrometeoroid Ablation Using a Dust Accelerator

A facility has been developed to simulate the ablation of micrometeoroids in laboratory conditions. An electrostatic dust accelerator is used to generate iron particles with velocities of 10-70 kilometers. The particles are then introduced into a chamber pressurized with a target gas, where the pressure is adjustable between 0.01 and 0.5 Torr, and the particle partially or completely ablates over a short distance. An array of biased electrodes above and below the ablation path is used to collect the generated ions/electrons with a spatial resolution of 2.6 centimeters along the ablating particles path, thus allowing the study of the spatiotemporal evolution of the process. For completely ablated particles, the total collected charge directly yields the ionization coefficient of a given dust material-target gas combination. The first results of this facility measured the ionization coefficient of iron atoms with N2, air, CO2, and He target gases for impact velocities greater than 20 kilometers per second, and are reported by Thomas et al. The ablation chamber is also equipped with four optical ports that allow for the detection of the light emitted by the ablating particle. A multichannel photomultiplier tube system is used to observe the ablation process with a spatial and temporal resolution of 0.64 centimeters and 90 nanoseconds. The preliminary results indicate that it is possible to calculate the velocity of the ablating particle from the optical observations, and in conjunction with the spatially resolved charge measurements allow for experimental validation of ablation models in future studies.

Thomas, Evan↗

Modern Muon Physics: Selected Issues

The muon was discovered almost hundred years ago, but still remains largely a mystery. For a long time, the only difference between a muon and an electron was the approximately 200 times greater mass of the muon. However, with the later discovery of the charm quantum number, the muon played a decisive role in the formulation of the Standard Model of elementary particles, determining together with muon neutrino and the strange s and the charm c quarks the second generation of particles of this model. The equality of the reaction constant of muon decay with the constant of the vector interaction of beta-decay played a decisive role in the formulation of the conservation of the vector current (CVC) of the weak interaction of elementary particles. Processes involving muons testified in favor of the partial conservation of the axial current of weak interaction (PCAC), that is, one pion exchange in the interaction of the lepton and hadron currents. It was the muon that gave a rise to hopes of creating an alternative energy source within the framework of Muon Catalyzed Fusion (μCF). The possible realization of this process in the future as the intensity of muon beams increases can revolutionired energy supply. Nuclear fission by muons and the study of heavy-nucleus mesoatoms introduced muon physics into several separate branches of physical research.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Fluid dynamic studies on scattering aerosol and its generation for application as tracer particles in supersonic flow measurements utilizing laser Doppler velocimeter

An experimental study on the particle-fluid interactions of scattering aerosols was performed using monodisperse aerosols of different particle sizes for the application of laser Doppler velocimeters in subsonic turbulence measurements. Particle response was measured by subjecting the particles to an acoustically excited oscillatory fluid velocity field and by comparing the ratio of particle velocity amplitude to the fluid velocity amplitude as a function of particle size and the frequency of oscillation. Particle velocity was measured by using a differential laser Doppler velocimeter. The test aerosols were fairly monodisperse with a mean diameter that could be controlled over the size range from 0.1 to 1.0 micron. Experimental results on the generation of a fairly monodisperse aerosol of solid particles and liquid droplets and on the aerosol response in the frequency range 100 Hz to 100 kHz are presented. It is indicated that a unit density spherical scatterer of 0.3 micron-diameter would be an optimum choice as tracer particles for subsonic air turbulence measurements.

Mazumder, M. K.↗

Sizing Accuracy of Low-Cost Optical Particle Sensors Under Controlled Laboratory Conditions

Low-cost particulate matter sensors have seen increased use for monitoring at personal and local levels due to their affordability, ease of operation, and high time resolution. However, the quality of data reported by these sensors can be questionable, and a thorough evaluation of their performance is necessary. This study evaluated the particle sizing accuracy of several commonly used optical sensors, including the Alphasense optical particle counter (OPC), TSI DustTrak DRX aerosol monitor, Plantower PMS5003 sensor, and Sensirion SPS30 sensor, using laboratory-generated monodisperse particles. The OPC and DRX agreed partially with reference instruments and showed promise in detecting coarse-size particles. However, the PMS5003 and SPS30 did not correctly size fine and coarse particles. Furthermore, their reported mass distributions do not directly correspond to their number distribution. Despite these limitations, field measurements involving a dust storm period showed that the SPS30 correlated reasonably well with reference instruments for both PM2.5 and PM10, though the regression slopes differed significantly. These findings underscore the need for caution when interpreting data from low-cost optical sensors, particularly for coarse particles. Recommendations for improving the performance of these sensors are also provided.

Gautam, Prakash↗

Prediction of energetic particle disturbances

The prediction of fluxes of energetic particles of solar or magnetospheric origin is addressed. Topics include the prediction of the properties of the particle populations generated by magnetospheric storms and substorms, and the prediction of long term variations in the populations of magnetospheric particles.

Paulikas, G. A.↗

The Effect of Solid Constituent Particle Size Distributions on TP-H1148 Propellant Slag

Special aluminum and ammonium perchlorate (AP) particle size distributions were prepared for a matrix of five-inch diameter, center-perforated (CP) motor tests to measure the aluminum oxide slag response in Space Shuttle Reusable Solid Rocket Motor (RSRM) propellant. Previous tests of TP-H1148 propellant in five-inch CP spin motors have shown a correlation between aluminum particle size and generated slag. The motors for this study were cast from thirteen five-gallon propellant mixes which used five particle size levels of aluminum powder, five of unground AP and three of ground AP. Aluminum had the greatest effect on slag formation, the more coarse fractions causing greater slag quantities and larger slag particles. Unground AP had about half the effect of aluminum with the coarser fractions again producing more and larger sized slag particles. The variation in ground AP did not have a significant effect on slag formation. Quench bomb tests showed the same trends as the spin motors, that is, larger aluminum and AP particle size distributions generated larger slag particles leaving the propellant surface. Cured propellant mechanical properties were also impacted by particle size variation.

May, Douglas H.↗

New particle pusher with hadronic interactions for modeling multimessenger emission from compact objects

We propose novel numerical schemes based on the Boris method in curved spacetime, incorporating both hadronic and radiative interactions for the first time. Once the proton has lost significant energy due to radiative and hadronic losses, and its gyroradius has decreased below typical scales on which the electromagnetic field varies, we apply a guiding center approximation (GCA). We fundamentally simulate collision processes either with a Monte-Carlo method or, where applicable, as a continuous energy loss, contingent on the local optical depth. To test our algorithm for the first time combining the effects of electromagnetic, gravitational, and radiation fields including hadronic interactions, we simulate highly relativistic protons traveling through various electromagnetic fields and proton backgrounds. We provide unit tests in various spatially dependent electromagnetic and gravitational fields and background photon and proton distributions, comparing the trajectory against analytic results. We propose that our method can be used to analyze hadronic interactions in black hole accretion disks, jets, and coronae to study the neutrino abundance from active galactic nuclei.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗