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At least 289 records · Page 16

Texture analysis of placental MRI: can it aid in the prenatal diagnosis of placenta accreta spectrum?

Purpose: To determine if texture analysis can differentiate placenta accreta spectrum (PAS) from normal placenta on MRI. Methods: We performed retrospective image analysis of 80 patients, comprised of 46 patients with PAS and 34 patients without PAS. Histopathology was used as the reference standard. Sagittal single shot fast spin echo T2-weighted MRI sequences acquired from a single institution were analyzed. Placental heterogeneity was quantified using in-house software on a Matlab platform, including the standard deviation of pixel intensity, coefficient of variation, gray-level co-occurrence matrices (GLCM), histogram-oriented gradients (HOG), and fractal analysis with box sizes from 2 to 512. Two-tailed unpaired Student’s t test was used with statistical significance of p < 0.05. Results: PAS was associated with higher values for standard deviation of pixel intensity and fractal analysis at every box size. Fractal analysis at box sizes 256 (p = 0.011) and 32 (p = 0.021), and standard deviation of pixel intensity (p = 0.023) were the most statistically significant. Fractal values at box size 256 for PAS was 0.13 versus 0.090 for patients without PAS, while standard deviation of pixel intensity was 3.7 for PAS versus 2.5 for patients without PAS. No statistically significant association between PAS and GLCM, coefficient of variation, and HOG was found. Conclusion: Statistically significant differences were found between normal and abnormal groups using standard deviation of pixel intensity and fractal analysis.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

PET/MRI of Hepatic 90Y Microsphere Deposition Determines Individual Tumor Response

PurposeThe purpose of our study is to determine if there is a relationship between dose deposition measured by PET/MRI and individual lesion response to yttrium-90 ({sup 90}Y) microsphere radioembolization.Materials and Methods26 patients undergoing lobar treatment with {sup 90}Y microspheres underwent PET/MRI within 66 h of treatment and had follow-up imaging available. Adequate visualization of tumor was available in 24 patients, and contours were drawn on simultaneously acquired PET/MRI data. Dose volume histograms (DVHs) were extracted from dose maps, which were generated using a voxelized dose kernel. Similar contours to capture dimensional and volumetric change of tumors were drawn on follow-up imaging. Response was analyzed using both RECIST and volumetric RECIST (vRECIST) criteria.ResultsA total of 8 hepatocellular carcinoma (HCC), 4 neuroendocrine tumor (NET), 9 colorectal metastases (CRC) patients, and 3 patients with other metastatic disease met inclusion criteria. Average dose was useful in predicting response between responders and non-responders for all lesion types and for CRC lesions alone using both response criteria (p < 0.05). D70 (minimum dose to 70 % of volume) was also useful in predicting response when using vRECIST. No significant trend was seen in the other tumor types. For CRC lesions, an average dose of 29.8 Gy offered 76.9 % sensitivity and 75.9 % specificity for response.ConclusionsPET/MRI of {sup 90}Y microsphere distribution showed significantly higher DVH values for responders than non-responders in patients with CRC. DVH analysis of {sup 90}Y microsphere distribution following treatment may be an important predictor of response and could be used to guide future adaptive therapy trials.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

A multimodel intercomparison of resolution effects on precipitation: simulations and theory

An ensemble of six pairs of RCM experiments performed at 25 and 50 km for the period 1961–2000 over a large European domain is examined in order to evaluate the effects of resolution on the simulation of daily precipitation statistics. Application of the non-parametric two-sample Kolmorgorov–Smirnov test, which tests for differences in the location and shape of the probability distributions of two samples, shows that the distribution of daily precipitation differs between the pairs of simulations over most land areas in both summer and winter, with the strongest signal over southern Europe. Two-dimensional histograms reveal that precipitation intensity increases with resolution over almost the entire domain in both winter and summer. In addition, the 25 km simulations have more dry days than the 50 km simulations. The increase in dry days with resolution is indicative of an improvement in model performance at higher resolution, while the more intense precipitation exceeds observed values. The systematic increase in precipitation extremes with resolution across all models suggests that this response is fundamental to model formulation. Simple theoretical arguments suggest that fluid continuity, combined with the emergent scaling properties of the horizontal wind field, results in an increase in resolved vertical transport as grid spacing decreases. This increase in resolution-dependent vertical mass flux then drives an intensification of convergence and resolvable-scale precipitation as grid spacing decreases. In conclusion, this theoretical result could help explain the increasingly, and often anomalously, large stratiform contribution to total rainfall observed with increasing resolution in many regional and global models.

54 ENVIRONMENTAL SCIENCES↗

Security enrichment of optical image cryptosystem based on superposition technique using fractional Hartley and gyrator transform domains deploying equal modulus decomposition

In this paper, a symmetric cryptosystem has been suggested to increase security of double random phase encoding using superposition technique in fractional Hartley transform (FrHT) and gyrator transform (GT) domains. It uses structured phase mask (SPM) and hybrid mask (HM) deploying equal modulus decomposition (EMD). Related to original phase truncated Fourier transform (PTFT) based cryptosystem, the security of encoding and decoding is upgraded by using the superposition technique. With the usage of SPM we can increase the key space while encoding and can also overcome the axis alignment difficulty. Decoding is just the reversal of the encoding method. The proposed scheme has robustness against common attacks like: noise and occlusion attacks. With the help of numerical simulation results we also show that our cryptosystem is vulnerable to various attacks. Performance of the suggested method is calculated in terms of Mean Square Error (MSE) between original and decoded image and also the sensitivity of the SPM parameters and rotational angles of GT is investigated. The competence of the suggested method includes analysis on EMD, histogram and correlation coefficient. The suggested cryptosystem is also open to the occlusion attack and noise attack to analyze its performance and evenness.

42 ENGINEERING↗

Image encryption and watermarking combined dynamic chaotic hopping pattern with double random phase encoding DRPE

In modern civilization information, security is a crucial problem. Image encryption and watermarking can effectively protect information from unauthorized access. This paper introduces a new vigorous symmetric optical image encryption and watermarking technique. This technique depends on a novel dynamic delay chaotic hopping pattern (DDCHP) combined with double random phase encoding (DRPE). To get a robust watermark image, the plain image is first watermarked with a binary secret message using a new chaotic hopping pattern (CHP) and then encrypted using a DRPE system that is controlled by double random independent keys generated with double DDCHP. In this symmetric cryptosystem, three different chaotic maps are used to enlarge the key space of the proposed cryptosystem against brute-force attack and overcome the linearity and vulnerable of the classical DRPE. The system keys are hypersensitive and their initial parameters are selected carefully. Security scrutiny proves the efficiency of the suggested cryptosystem. Therefore, the obtained simulation results prove that the cryptosystem is robust enough against the known attacks, such as statistical attack (uniform histograms of different encrypted images, correlation coefficients between the plain and the encrypted image is as low as 5.46 × 10{sup −6}), differential attack (99.99% NPCR and 38.6% UACI), brute force attack (large enough key space), and entropy attack. Moreover, the robustness of the watermark (secret message) is proved due to the solidity of CHP. The proposed approach can be used in different implementations like secure military communications, e-finance, e-healthcare, authenticated multimedia broadcasting, etc.

97 MATHEMATICS AND COMPUTING↗

Tempering of low-temperature bainite

Electron microscopy, X-ray diffraction, and atom probe tomography have been used to identify the changes which occur during the tempering of a carbide-free bainitic steel transformed at 473 K (200 °C). Partitioning of solute between ferrite and thin-films of retained austenite was observed on tempering at 673 K (400 °C) for 30 minutes. After tempering at 673 K (400 °C) and 773 K (500 °C) for 30 minutes, cementite was observed in the form of nanometre scale precipitates. Here, proximity histograms showed that the partitioning of solutes other than silicon from the cementite was slight at 673 K (400 °C) and more obvious at 773 K (500 °C). In both cases, the nanometre scale carbides are greatly depleted in silicon.

36 MATERIALS SCIENCE↗

Study of the Thermomechanical Performance of FR-4 Laminates During the Reflow Process

The behavior of FR4 laminates for printed circuit boards (PCBs) during a double reflow process and the main factors associated with warpage are discussed. The microstructure, glass transition temperature (T{sub g}), decomposition temperature (T{sub d}), coefficient of thermal expansion (CTE), time to delamination and % water absorption were characterized, and the temperature profiles in the board during its pass through the reflow oven were recorded. Bow and twist measurements were taken on a set of 30 PCBs. Both T{sub d} and T{sub g} were found to be below their nominal values. The CTE is highly anisotropic and vary at different locations, and it is more than three times higher in the through thickness middle section with respect to the bottom and top locations. Temporary temperature gradients of more than 50 degrees between different locations were detected at the start of the reflow step as a result, the bow values were found to be strongly anisotropic, particularly after the first reflow, in which different sides can present bow values up to more than six times higher than others, with maxima values of 0.47 mm. The anisotropy of the CTE appears to affect only slightly the twist values. Compared with the first reflow, the bow and twist values are lower, exhibit less dispersion and are more homogeneous for the second reflow. The histograms of both bow and twist do not seem to follow a normal distribution, possibly as a result of the combined effect of spatial variations and anisotropy of properties as well as the temperature gradients during reflow.

36 MATERIALS SCIENCE↗

An Algorithm to Generate Synthetic 3D Microstructures from 2D Exemplars

The inverse problem of constructing 3D microstructures from 2D data is an area of active research within the materials science community. This paper presents the implementation of a robust, computationally efficient algorithm, Hierarchical Algorithm for the Reconstruction of Exemplars (HARE), written in Python to reconstruct 3D features in a given microstructure from up to three orthogonal 2D exemplars using nearest neighbor matching to reproduce feature qualities, such as shape, size, and distribution. HARE’s feature sampling implements histogram reweighting to avoid both over- and undersampling. A neighborhood voting scheme allows each pixel to provisionally affect its neighbors according to its weight. Finally, the algorithm is presently configured for two-phase materials and is being extended to accommodate multiple phases. HARE is a convenient and robust base from which to generate statistically representative synthetic microstructures for use in multi-scale modeling or machine learning applications to support advanced manufacturing and materials discovery.

36 MATERIALS SCIENCE↗

Comparison of CZT SPECT and conventional SPECT for assessment of contractile function, mechanical synchrony and myocardial scar in patients with heart failure

Aim: The aim of this study was to compare CZT-SPECT (CZT SPECT) to conventional SPECT (C-SPECT) in the assessment of left ventricular myocardial scar, contractile function, and mechanical synchrony in patients with heart failure (HF). Methods: Fifty-nine patients with HF who were referred for myocardial perfusion/metabolism imaging were enrolled. All patients underwent resting {sup 99m}Tc-MIBI gated myocardial perfusion imaging using a CZT SPECT camera and a C-SPECT camera, respectively, and {sup 18}F-FDG PET myocardial metabolism imaging within three days. Summed rest score (SRS) and total perfusion defect (TPD) (as indices of perfusion abnormality), left ventricular (LV), end diastolic volume (EDV), end systolic volume (ESV), and ejection fraction (EF) (as indices of LV systolic function), and histogram band width (BW) and standard deviation (SD) (as indices of mechanical synchrony) were analyzed by automated software while the perfusion/metabolism patterns were analyzed visually. Results: There was a good correlation between CZT SPECT and C-SPECT for SRS and TPD. CZT SPECT tended to underestimate SRS and TPD compared to C-SPECT. CZT-SPECT and C-SPECT showed excellent agreement in assessing the perfusion/metabolism pattern though a small proportion of normal segments (6.6%) identified by CZT/PET exhibited mismatch pattern on C-SPECT/PET. CZT SPECT also showed excellent correlation with C-SPECT in measuring EDV, ESV, and EF. Finally, BW and SD measured by CZT SPECT correlated well with C-SPECT but CZT SPECT tended to overestimate BW and SD compared to C-SPECT. Conclusion: CZT SPECT provided comparable data to C-SPECT for measuring LV scar, function and synchrony at a considerable reduction in imaging time. CZT SPECT holds a promise for comprehensive evaluation of myocardial performance in patients with HF.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Physical Regime Sensitivity

Abstract This work presents a novel sensitivity approach that quantifies sensitivity to regimes of a model’s state variables rather than constitutive model parameters. This Physical Regime Sensitivity (PRS) determines which regimes of a model’s independent variables have the biggest influence on an experiment or application. PRS analysis is demonstrated on a strength model used in the simulation of a copper Taylor cylinder. In a series of simulations, the strength model was perturbed sequentially in local regimes of plastic strain, plastic strain rate, temperature and pressure, and then the prediction of cylinder shape was compared to unperturbed calculations. Results show, for example, that the deformed length of the cylinder was most sensitive to strength at a strain rate of 1.0 × 10 4 /sec., but the deformed footprint radius was most sensitive to strength at a strain rate of about 4.0 × 10 4 /sec. Compared to current histogram approaches, PRS can be used to design or interpret integrated experiments by identifying not just which regimes are accessed somewhere in the experiment but the causality question of which regimes actually affect the measured data. PRS should allow one to focus experimental and modeling efforts where they are most needed and to better interpret experiments.

36 MATERIALS SCIENCE↗

Carbon concentration measurements by atom probe tomography in the ferritic phase of high-silicon steels

Current studies using atom probe tomography (APT) show that bainitic ferrite formed at low temperature contains more carbon than what is consistent with the paraequilibrium phase diagram. However, nanocrystalline bainitic ferrite exhibits a non-homogeneous distribution of carbon atoms in arrangements with specific compositions, i.e. Cottrell atmospheres, carbon clusters, and carbides, in most cases with a size of a few nanometers. The ferrite volume within a single platelet that is free of these carbon-enriched regions is extremely small. Proximity histograms can be compromised on the ferrite side, and a great deal of care should be taken to estimate the carbon content in regions of bainitic ferrite free from carbon agglomeration. For this purpose, APT measurements were first validated for the ferritic phase in a pearlitic sample and further performed for the bainitic ferrite matrix in high-silicon steels isothermally transformed between 200 °C and 350 °C. Additionally, results were compared with the carbon concentration values derived from X-ray diffraction (XRD) analyses considering a tetragonal lattice and previous APT studies. In conclusion, the present results reveal a strong disagreement between the carbon content values in the bainitic ferrite matrix as obtained by APT and those derived from XRD measurements. Those differences have been attributed to the development of carbon-clustered regions with an increased tetragonality in a carbon-depleted matrix.

36 MATERIALS SCIENCE↗

Mechanical properties of nanoporous gold in tension

We report results of the tensile properties of nanoporous gold (NPG) as a function of the density and average ligament diameter. As-dealloyed tensile samples were thermally treated to coarsen the length scale of the NPG structure while increasing the sample density resulting from thickness reductions. The behaviors of samples with mean ligament diameters ranging from 30 to 750 nm and corresponding densities ranging from 0.30 to 0.57 that of bulk gold were examined. Digital image analysis was used to obtain ligament size histograms that were fit to the Weibull distribution. The Young's modulus was found to obey a power law, but with an exponent larger than that predicted by Gibson-Ashby scaling. The fracture behavior showed a brittle-ductile transition as a function of increasing ligament size. For samples characterized by a mean ligament diameter less than ~ 220 nm, the tensile behavior was linear elastic to sample fracture while samples with larger scale ligaments showed macroscopic yielding prior to fracture. These results are interpreted within the framework of extreme value statistics.

36 MATERIALS SCIENCE↗

Multiresolution classification of turbulence features in image data through machine learning

During large-scale simulations, intermediate data products such as image databases have become popular due to their low relative storage cost and fast in-situ analysis. Serving as a form of data reduction, these image databases have become more acceptable to perform data analysis on. In this work, we present an image-space detection and classification system for extracting vortices at multiple scales through wavelet-based filtering. A custom image-space descriptor is used to encode a large variety of vortex-types and a machine learning system is trained for fast classification of vortex regions. By combining a radial-based histogram descriptor, a bag of visual words feature descriptor, and a support vector machine, our results show that we are able to detect and classify vortex features at various sizes at multiple scales. Once trained, our framework enables the fast extraction of vortices on new, unknown image datasets for flow analysis.

97 MATHEMATICS AND COMPUTING↗

Quantification of synthesized hydration products using synchrotron microtomography and spectral analysis

The use of x-ray computed tomography (CT) as a standalone method has primarily been used to characterize pore structure, cracking and mechanical damage in cementitious systems due to low contrast in the hydrated phases. These limitations have resulted in the inability to extract quantifiable information on such phases. The goal of this research was to address the limitations caused by low contrast and improving the ability to distinguish the four primary hydrated phases in portland cement; C-S-H, calcium hydroxide, monosulfate, and ettringite. X-ray CT on individual layers, binary mixtures of phases, and quaternary mixtures of phases to represent a hydrated portland cement paste were imaged with synchrotron radiation. Known masses of each phase were converted to a volume and compared to the segmented image volumes. It was observed that adequate contrast in binary mixing of phases allowed for segmentation, and subsequent image analysis indicated quantifiable volumes could be extracted from the tomographic volume. However, low contrast was observed when C-S-H and monosulfate were paired together leading to difficulties segmenting in an unbiased manner. Quantification of phases in quaternary mixtures included larger errors than binary mixes due to histogram overlaps of monosulfate, C-S-H, and calcium hydroxide.

36 MATERIALS SCIENCE↗

GPU acceleration and performance of the particle-beam-dynamics code Elegant

Elegant is an accelerator physics and particle-beam dynamics code widely used for modeling and design of a variety of high-energy particle accelerators and accelerator-based systems. We discuss a recently developed version of the code that can take advantage of CUDA-enabled graphics processing units (GPUs) to achieve significantly improved performance for a large class of simulations that are important in practice. The GPU version is largely defined by a framework that simplifies implementations of the fundamental kernel types that are used by Elegant: particle operations, reductions, particle loss, histograms, array convolutions and random number generation. Accelerated performance on the Titan Cray XK-7 supercomputer is approximately 6–10 times better with the GPU than all the CPU cores associated with the same node count. In addition to performance, the maintainability of the GPU-accelerated version of the code was considered a key design objective. Accuracy with respect to the CPU implementation is also a core consideration. Finally, four different methods are used to ensure that the accelerated code faithfully reproduces the CPU results.

43 PARTICLE ACCELERATORS↗

Accelerating multicanonical sampling with irreversibility

Flat-histogram Monte Carlo simulations are well-established, robust methods to perform random walks in a physical observable or parameter space, making them suitable for finding ground states or studying phase transitions in complex systems in statistical physics. However, their efficiency can be limited by the time to attain the desired flat distribution, which is generally unknown prior to the simulations. In particular, they might suffer from slowing down towards the end of a simulation due to the diffusive nature of random walks. In this work we apply irreversibility to the multicanonical Monte Carlo method via the lifting approach to alleviate this behavior. We achieve a 2–4 times speedup in ground-state search for a two-dimensional (2D) Ising model, and up to an order of magnitude of speedup for finding the ground-state energy in an Edwards–Anderson spin glass, compared to traditional multicanonical sampling. In conclusion, the round-trip times between ground states show a narrower distribution and are significantly shorter compared to the reversible counterpart, suggesting that a lower convergence time with a smaller time variance is feasible.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Data on Cu- and Ni-Si-Mn-rich solute clustering in a neutron irradiated austenitic stainless steel

The data presented in this article is supplementary to the research article “Phase instabilities in austenitic steels during particle bombardment at high and low dose rates” (Levine et al.). Needle-shaped samples were prepared with focused ion beam milling from a 304L stainless steel that was irradiated with fast neutrons (E 0.1 MeV) in the BOR-60 reactor at 318 °C to 47.5 dpa. Atom probe tomography (APT) experiments in voltage mode were then conducted on a Cameca LEAP 5000X HR. Atom position, range, and mass spectrum files after reconstruction with Cameca’s IVAS software are included. Cu- and Ni-Si-Mn-rich solute nanoclusters were identified and analyzed using the Open Source Characterization of APT Reconstructions (OSCAR) program. Python code for OSCAR, information on the program’s underlying algorithm, and sample output files are provided. A proximity histogram of a Ni-Si-Mn-rich cluster and a 1D density/solute concentration profile of a Cu-rich cluster are given to demonstrate OSCAR’s analytical functionalities. The provided APT dataset is valuable for benchmarking phase instabilities in neutron-irradiated austenitic stainless steels that occur at high doses. The OSCAR program can be reused to process other APT data sets where solute nanoclustering is of interest.

42 ENGINEERING↗