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At least 271 records · Page 15

Predicting sudden cardiac death from T wave alternans of the surface electrocardiogram: promise and pitfalls

Sudden cardiac death remains a preeminent public health problem. Despite advances in preventative treatment for patients known to be at risk, to date we have been able to identify, and thus treat, only a small minority of these patients. Therefore, there is a major need to develop noninvasive diagnostic technologies to identify patients at risk. Recent studies have demonstrated that measurement of microvolt-level T wave alternans is a promising technique for the accurate identification of patients at risk for ventricular arrhythmias and sudden cardiac death. In this article, we review the clinical data establishing the relationship between microvolt T wave alternans and susceptibility to ventricular arrhythmias. We also review the methods and technology that have been developed to measure microvolt levels of T wave alternans noninvasively in broad populations of ambulatory patients. In particular, we examine techniques that permit the accurate measurement of T wave alternans during exercise stress testing.

Review, Tutorial↗

QCD-collapsed domain walls: QCD phase transition and gravitational wave spectroscopy

Abstract For a discrete symmetry that is anomalous under QCD, the domain walls produced in the early universe from its spontaneous breaking can naturally annihilate due to QCD instanton effects. The gravitational waves generated from wall annihilation have their amplitude and frequency determined by both the discrete symmetry breaking scale and the QCD scale. The evidence of stochastic gravitational waves at nanohertz observed by pulsar timing array experiments suggests that the discrete-symmetry-breaking scale is around 100 TeV, assuming the domain-wall explanation. The annihilation temperature is about 100 MeV, which could naturally be below the QCD phase transition temperature. We point out that the QCD phase transition within some domains with an effective large QCDθangle could be a first-order one. To derive the phase diagram inθand temperature, we adopt a phenomenological linear sigma model with three quark flavors. The domain-wall explanation for the NANOGrav, EPTA, PPTA and CPTA results hints at a first-order QCD phase transition, which predicts additional gravitational waves at higher frequencies. If the initial formation of domain walls is also a first-order process, this class of domain-wall models predicts an interesting gravitational wave spectroscopy with frequencies spanning more than ten orders of magnitude, from nanohertz to 100 Hz.

Physics↗

In-process monitoring and prediction of droplet quality in droplet-on-demand liquid metal jetting additive manufacturing using machine learning

Abstract In droplet-on-demand liquid metal jetting (DoD-LMJ) additive manufacturing, complex physical interactions govern the droplet characteristics, such as size, velocity, and shape. These droplet characteristics, in turn, determine the functional quality of the printed parts. Hence, to ensure repeatable and reliable part quality it is necessary to monitor and control the droplet characteristics. Existing approaches for in-situ monitoring of droplet behavior in DoD-LMJ rely on high-speed imaging sensors. The resulting high volume of droplet images acquired is computationally demanding to analyze and hinders real-time control of the process. To overcome this challenge, the objective of this work is to use time series data acquired from an in-process millimeter-wave sensor for predicting the size, velocity, and shape characteristics of droplets in DoD-LMJ process. As opposed to high-speed imaging, this sensor produces data-efficient time series signatures that allows rapid, real-time process monitoring. We devise machine learning models that use the millimeter-wave sensor data to predict the droplet characteristics. Specifically, we developed multilayer perceptron-based non-linear autoregressive models to predict the size and velocity of droplets. Likewise, a supervised machine learning model was trained to classify the droplet shape using the frequency spectrum information contained in the millimeter-wave sensor signatures. High-speed imaging data served as ground truth for model training and validation. These models captured the droplet characteristics with a statistical fidelity exceeding 90%, and vastly outperformed conventional statistical modeling approaches. Thus, this work achieves a practically viable sensing approach for real-time quality monitoring of the DoD-LMJ process, in lieu of the existing data-intensive image-based techniques.

Gaikwad, Aniruddha (ORCID:0000000285642621)↗

Predicting SLS Launch Environment using a Novel Multiphase Formulation

Powerful acoustic waves generated during ignition of launch vehicles may be dangerous to the vehicle, its payload, or the surrounding structures. The water-based Ignition Overpressure and Sound Suppression (IOP/SS) system at Kennedy Space Center’s (KSC) Launch Complex 39B (LC-39B) will be used to protect the Space Launch System (SLS) from the acoustic vibrations generated during launch. The IOP/SS system uses enormous amounts of water to dampen and attenuate these sound waves. To better understand the launch environment risks and to study the effectiveness of the IOP/SS system it is desirable to have time-accurate unsteady simulations of the vehicle ignition with water-based sound suppression. This paper presents results obtained with a novel, high-order accurate, and robust numerical method designed for simulating compressible multiphase flows. A positivity-preserving finite difference scheme is utilized which is formally high-order accurate and also provably robust. Robustness is critical due to the extreme nature of the flow which exhibits highly nonlinear shock and rarefaction waves interacting with liquid-gas interfaces with density ratios of the order of 1000:1. Furthermore, the high-order accuracy (and the high resolution property) is desirable for predicting wave phenomena like IOP waves since the signal can be resolved accurately and propagated long distances with fewer grid points. This finite-difference method was developed using NASA’s Launch, Ascent, and Vehicle Aerodynamics (LAVA) Cartesian immersed boundary framework. We present a validation case by applying our solver to the SLS Scale Model Acoustic Test (SMAT). The SLS SMAT is a well-instrumented 5% scale model test meant to represent the SLS at NASA KSC’s LC-39B pad. Scale IOP tests were performed with and without the sound suppression water and included many sensors which recorded the pressure waves produced during ignition. For this validation case we conduct two simulations, likewise with and without sound suppression water, and compare the SLS SMAT pressure sensor signals with our numerical signals at identical locations. Following this validation case we present a study of the SLS launch environment to examine engineering safety concerns about the mobile launch pad. Engineers at KSC redesigned the main flame deflector at LC-39B anticipating the increased loads from the SLS and to repair damage from prior Shuttle missions. This deflector redesign made use of surface pressure and temperature data from LAVA full-scale SLS simulations without the sound suppression system. The engineers were questioning the possibility of increased pressure loads on the underside of the mobile launcher due to the water in the flame trench. Based on the results established in our simulations of the SLS SMAT, we performed updated calculations for SLS at LC-39B with and without water systems active to assess the readiness of the launch pad for Artemis I launch. Our results show that the IOP/SS system is effective at reducing the overpressure signal and overall sound pressure levels felt by the vehicle and additionally that the pressure loads experienced by the mobile launcher (ML) during engine startup is not increased by the presence of water.

EGS↗

Lower stratosphere waves during 1986-1989 southern springs

Global NMC height analyses and Nimbus 7 TOMS Grid-T Version 6 data are used to investigate the horizontal structure of ozone and 50-mb height waves for the 1986-1989 springs of the Southern Hemisphere. Empirical orthogonal functions (EOFs) are obtained for the ozone and height data independently to identify the meridional structure of observed long waves as well as their propagation characteristics. The leading EOFs for both the ozone and 50-mb height waves exhibit wavenumber 1 and 2 patterns. The correlation coefficients between ozone and 50-mb height principal components are high. They indicate high/low ozone values associated with high/low values of 50-mb heights. This distribution is consistent with the advection of ozone by planetary waves south of the ozone maximum, as shown by a simple linear wave model. The observed total ozone amplitudes for waves 1 and 2 for most years are consistent with the total ozone predictions by the wave model.

Nogues-Paegle, Julia↗

Euler flow predictions for an oscillating cascade using a high resolution wave-split scheme

A compressible flow code that can predict the nonlinear unsteady aerodynamics associated with transonic flows over oscillating cascades is developed and validated. The code solves the two dimensional, unsteady Euler equations using a time-marching, flux-difference splitting scheme. The unsteady pressures and forces can be determined for arbitrary input motions, although only harmonic pitching and plunging motions are addressed. The code solves the flow equations on a H-grid which is allowed to deform with the airfoil motion. Predictions are presented for both flat plate cascades and loaded airfoil cascades. Results are compared to flat plate theory and experimental data. Predictions are also presented for several oscillating cascades with strong normal shocks where the pitching amplitudes, cascade geometry and interblade phase angles are varied to investigate nonlinear behavior.

Huff, Dennis L.↗

Euler flow predictions for an oscillating cascade using a high resolution wave-split scheme

A compressible flow code that can predict the nonlinear unsteady aerodynamic associated with transonic flows over oscillating cascades is developed and validated. The code solves the two dimensional, unsteady Euler equations using a time-marching, flux-difference splitting scheme. The unsteady pressures and forces can be determined for arbitrary input motions, although only harmonic pitching and plunging motions are addressed. The code solves the flow equations on a H-grid which is allowed to deform with the airfoil motion. Predictions are presented for both flat plate cascades and loaded airfoil cascades. Results are compared to flat plate theory and experimental data. Predictions are also presented for several oscillating cascades with strong normal shocks where the pitching amplitudes, cascade geometry and interblade phase angles are varied to investigate nonlinear behavior.

Huff, Dennis L.↗

A comparison between numerically modelled and experimentally measured loss mechanisms in wave rotors

A numerical model has been developed which is capable of predicting the performance of a wave rotor (pressure exchanger) of specified geometry over a wide range of operating conditions. The model can account for the major loss mechanisms of leakage from the tube ends, fluid viscosity, heat transfer to the tube wails, finite tube opening time, shock waves, and non-uniform port flows. It is a one dimensional flow model which follows a single tube as it rotates past the various stationary ports. Since the model is relatively simple (i.e., one dimensional) it uses little computer time. This makes it suitable for design as well as analytical purposes. This paper will present a brief description of the model then discuss a comparison between the model predictions and several wave rotor experiments.

Paxson, Daniel E.↗

A Comparison Between Numerically Modelled and Experimentally Measured Loss Mechanisms in Wave Rotors

A numerical model has been developed which is capable of predicting the performance of a wave rotor (pressure exchanger) of specified geometry over a wide range of operating conditions. The model can account for the major loss mechanisms of leakage from the tube ends, fluid viscosity, heat transfer to the tube walls, finite tube opening time, shock waves, and non-uniform port flows. It is a one dimensional flow model which follows a single tube as it rotates past the various stationary ports. Since the model is relatively simple (i.e. one dimensional) it uses little computer time. This makes it suitable for design as well as analytical purposes. This paper will present a brief description of the model then discuss a comparison between the model predictions and several wave rotor experiments.

Paxson, Daniel E.↗

Analytic numerical solutions for shock waves

Study of weak solutions of simple wave equation, inviscid Burgers equation, and Euler equations has resulted in technique for accurate prediction of shock waves occurring in inviscid supersonic flows.

Maccormack, R. W.↗

Starting-point-independent quantum Monte Carlo calculations of iron oxide

Quantum Monte Carlo (QMC) methods are useful for studies of strongly correlated materials because they are many body in nature and use the physical Hamiltonian. Typical calculations assume as a starting point a wave function constructed from single-particle orbitals obtained from one-body methods, e.g., density functional theory. However, mean-field-derived wave functions can sometimes lead to systematic QMC biases if the mean-field result poorly describes the true ground state. In this study, we examine the accuracy and flexibility of QMC trial wave functions using variational and fixed-node diffusion QMC estimates of the total spin density and lattice distortion of antiferromagnetic iron oxide (FeO) in the ground state B1 crystal structure. We found that for relatively simple wave functions the predicted lattice distortion was controlled by the choice of single-particle orbitals used to construct the wave function, rather than by subsequent wave function optimization techniques within QMC. By optimizing the orbitals with QMC, we then demonstrate starting-point independence of the trial wave function with respect to the method by which the orbitals were constructed by demonstrating convergence of the energy, spin density, and predicted lattice distortion for two qualitatively different sets of orbitals. The results suggest that orbital optimization is a promising method for accurate many-body calculations of strongly correlated condensed phases.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Monitoring Preferential Flow of Water in Sand Using Thermoacoustics Wave Imaging

Abstract Accurate predictions of fluid flow, mass transport, and reaction rates critically impact the efficiency and reliability of subsurface exploration and sustainable use of subsurface resources. Quantitative dynamical sensing and imaging can play a pivotal role in the ability to make such predictions. Geophysical thermoacoustic technology has the potential to provide the aforementioned capabilities, since it builds upon the principle that electromagnetic and mechanical wave fields can be coupled through a thermodynamic process. In this letter, we present laboratory experiments featuring the efficacy of thermoacoustic imaging in the monitoring of preferential flow of water in porous media. Our laboratory experimental equipment can be readily packaged in a form factor that fits in a borehole, and the use of multiple acoustic transducers—which can be combined with volumetric coding techniques—has the potential to provide quasi‐real‐time imaging (0.5 Hz video rate) of regions in close proximity (a few meters) of an open field well.

Geology↗

Uncertainty-Guided Prediction Horizon of Phase-Resolved Ocean Wave Forecasting Under Data Sparsity: Experimental and Numerical Evaluation

Accurate short-term wave forecasting is critical for the safe and efficient operation of marine structures that rely on real-time, phase-resolved ocean wave information for control and monitoring purposes (e.g., digital twins). These systems often depend on environmental sensors (e.g., waverider buoys, wave-sensing LIDAR). Challenges arise when upstream sensor data are missing, sparse, or phase-shifted due to drift. This study investigates the performance of two machine learning models, time-series dense encoder (TiDE) and long short-term memory (LSTM), for forecasting phase-resolved ocean surface elevations under varying degrees of data degradation. We introduce the τ-trimming algorithm, which adapts the prediction horizon based on uncertainty thresholds derived from historical forecasts. Numerical wave tank (NWT) and wave basin experiments are used to benchmark model performance under short- and long-term data masking, spatially coarse sensor grids, and upstream phase shifts. Results show under a 50% probability of upstream data loss, the τ-trimmed TiDE model achieves a 46% reduction in error at the most upstream target, compared to 22% for LSTM. Furthermore, phase misalignment in upstream data introduces a near-linear increase in forecast error. Under moderate model settings, a ±3 s misalignment increases the mean absolute error by approximately 0.5 m, while the same error is accumulated at ±4 s using the more conservative approach. These findings inform the design of resilient, uncertainty-aware wave forecasting systems suited for realistic offshore sensing environments.

42 ENGINEERING↗

Theoretical prediction of interference loading on aircraft stores. Part 2: Supersonic speeds

A method is developed for theoretically predicting the loading on pylon-mounted stores in supersonic flow. Linear theory is used, without two dimensional or slender body assumptions, to predict the flow field produced by the aircraft wing, nose, inlet, and pylons. Aircraft shock wave locations are predicted, and their effect on the flow field is included through a transformation of the aircraft geometry. The interference loading is integrated over the store length by considering the local crossflow, its axial and radial derivatives, and buoyancy. Store moment calculations under an F-4 aircraft at Mach 1.2 are compared to wind tunnel data. The method is computerized, and program user information is included.

Danfernandes, F.↗