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At least 271 records · Page 15

Connecting the Radiative Influences of Aerosol upon the Mass Flux Profiles of Shallow Cumuli across the Southeast Atlantic Ocean Basin and its Boundaries (Final Report)

The Atlantic Ocean covers approximately 25% of Earth’s surface and the atmosphere above it is home to a complex array of clouds and aerosols that have important influences on regional and global weather and climate. These influences must be accurately depicted in short range, medium range, seasonal, and climate forecast models. Conditions over the tropical Atlantic are particularly complex due to continental scale plumes of dust from the Sahara Desert and smoke from agricultural burning in Africa that drift across the Atlantic Ocean basin toward the Americas. These plumes are often found meandering in the lower atmosphere above shallow tropical clouds that form above the ocean surface, presumably mingling with these clouds on occasion due to convective mixing processes. Elevated dust and smoke particles absorb incoming sunlight and substantially warm the marine atmosphere in the layer in which they are present. This warming may alter the thermal stability of the marine atmosphere and may throttle or enhance the development of clouds, change their internal structure and the rate at which they precipitate. Alternatively, it may isolate the lower atmosphere from drier layers above enabling water vapor to accumulate near the ocean surface potentially leading to the development of deeper convection. Our study was organized around the principal concept of determining the impact of African smoke and dust plumes upon cloud development at ASI and understanding how a popular shallow convection parameterization used in models responds to the presence of this aerosol. We analyzed observations collected during the US Department of Energy (DOE) Layered Atlantic Smoke Interactions with Clouds (LASIC) campaign using the Atmospheric Radiation Measurement Program’s Mobile Facility #1 (AMF-1), which was deployed to Ascension Island (ASI) in Southeastern Atlantic for a one-year period. Ascension Island is immediately downwind from an African source of these plumes, but far enough removed to enable the lower atmosphere to have reacted to their presence. A main goal of our study was to compute radiative heating rate profiles over Ascension Island and along the trajectory from the biomass burning regions along coastal Africa to Ascension Island. To compute the radiative heating rate due to aerosols and clouds, we employed observed profiles of temperature, humidity, and clouds from LASIC alongside aerosol optical properties from the Modern-era Retrospective analysis for Research and Applications Version 2 (MERRA-2), as input for the Rapid Radiation Transfer Model (RRTM). Radiative heating was also assessed across the southeast Atlantic Ocean using an ensemble of back trajectories from the Hybrid Single Particle Lagrangian Integrated Trajectory (HYSPLIT) model. We were successful in this effort and the resulting publication is already being cited despite its relatively short lifetime in the literature. The second part of our study involved the process-level representation of the clouds observed over the Southeastern Atlantic in models. Our initial task, upon which the balance of this portion of the study depended, was to evaluate the representativeness of the clouds observed by AMF-1. What orographic influence did Ascension Island have on the measured cloud structure? We set out to answer this question by trying to separate observations that were clearly indicative of orographic forcing from those that were representative of open ocean. The siting of AMF-1, which was 340-m above sea-level on the slope of a steep escarpment, proved demonstrably problematic for cloud process measurements. Despite considerable effort using multiple approaches including artificial intelligence (AI), we were unable to successfully compensate for the orographic forcing present at the AMF-1 site on ASI and, hence, produce process-level summaries of the convective mass flux representative of open ocean over the Southeastern Atlantic. Even though the project has officially ended, we are making a final attempt using two new types of clustering algorithm (i.e., AI) on the recommendation of a former student, who is an expert in this area. Since we have only recently begun to test these new AI schemes, the recommendations from the second part of our project outlined below are based on our experience at the time of this report.

54 ENVIRONMENTAL SCIENCES↗

Attribution of the role of climate change in the forest fires in Sweden 2018

In this study, we analyse the role of climate change in the forestfires that raged through large parts of Sweden in the summer of 2018 from ameteorological perspective. This is done by studying the Canadian FireWeather Index (FWI) based on sub-daily data, both in reanalysis data sets(ERA-Interim, ERA5, the Japanese 55 year Reanalysis, JRA-55, and Modern-Era Retrospective analysis for Research and Applications version 2, MERRA-2) and three large-ensemble climatemodels (EC-Earth, weather@home, W@H, and Community Earth System Model, CESM) simulations. The FWI, based on reanalysis, correlates well with the observed burnt area in summer (r=0.6 to 0.8). We find that the maximum FWI in July 2018 had return times of ~24 years (90 % CI, confidence interval, > 10 years) for southern and northern Sweden. Furthermore, we find a negative trend of the FWI for southern Sweden over the 1979 to 2017 time period in the reanalyses, yielding a non-significant reduced probability of such an event. However, the short observational record, large uncertainty between the reanalysis products and large natural variability of the FWI give a large confidence interval around this number that easily includes no change, so we cannot draw robust conclusions from reanalysis data. The three large-ensembles with climate models point to a roughly 1.1 (0.9 to 1.4) times increased probability (non-significant) for such events in the current climate relative to preindustrial climate. For a future climate (2 °C warming), we find a roughly 2 (1.5 to 3) times increased probability for such events relative to the preindustrial climate. The increased fire weather risk is mainly attributed to the increase intemperature. The other main factor, i.e. precipitation during summer months, isprojected to increase for northern Sweden and decrease for southern Sweden. We, however, do not find a clear change in prolonged dry periods in summer months that could explain the increased fire weather risk in the climate models. In summary, we find a (non-significant) reduced probability of such eventsbased on reanalyses, a small (non-significant) increased probability due to global warming up to now and a more robust (significant) increase in the risk for such events in the future based on the climate models.

54 ENVIRONMENTAL SCIENCES↗

Crew Factors in Flight Operations XII: A Survey of Sleep Quantity and Quality in On-Board Crew Rest Facilities

Many aircraft operated on long-haul commercial airline flights are equipped with on-board crew rest facilities, or bunks, to allow crewmembers to rest during the flight. The primary objectives of this study were to gather data on how the bunks were used, the quantity and quality of sleep obtained by flight crewmembers in the facilities, and the factors that affected their sleep. A retrospective survey comprising 54 questions of varied format addressed demographics, home sleep habits, and bunk sleep habits. Crewmembers from three airlines with long-haul fleets carrying augmented crews consisting of B747-100/200, B747-400, and MD-11 aircraft equipped with bunks returned a total of 1404 completed surveys (a 37% response rate). Crewmembers from the three carriers were comparable demographically, although one carrier had older, more experienced flight crewmembers. Each group, on average, rated themselves as "good" or "very good" sleepers at home, and all groups obtained about the same average amount of sleep each night. Most were able to sleep in the bunks, and about two thirds indicated that these rest opportunities benefited their subsequent flight deck alertness and performance. Comfort, environment, and physiology (e.g., being ready for sleep) were identified as factors that most promoted sleep. Factors cited as interfering with sleep included random noise, thoughts, heat, and the need to use the bathroom. These factors, in turn, suggest potential improvements to bunk facilities and their use. Ratings of the three aircraft types suggested differences among facilities. Bunks in the MD-11 were rated significantly better than either of the B747 types, and the B747-400 bunks received better ratings than did the older, B747-100/200 facilities.

Rosekind, Mark R.↗

Climatology and surface impacts of atmospheric rivers on West Antarctica

Abstract. Atmospheric rivers (ARs) transport large amounts of moisture from the mid- to high-latitudes and they are a primary driver of the most extreme snowfall events, along with surface melting, in Antarctica. In this study, we characterize the climatology and surface impacts of ARs on West Antarctica, focusing on the Amundsen Sea Embayment and Marie Byrd Land. First, we develop a climatology of ARs in this region, using an Antarctic-specific AR detection tool combined with the Modern-Era Retrospective analysis for Research and Applications, version 2 (MERRA-2) and the European Centre for Medium-Range Weather Forecasts (ECMWF) Reanalysis v5 (ERA5) atmospheric reanalyses. We find that while ARs are infrequent (occurring 3 % of the time), they cause intense precipitation in short periods of time and account for 11 % of the annual surface accumulation. They are driven by the coupling of a blocking high over the Antarctic Peninsula with a low-pressure system known as the Amundsen Sea Low. Next, we use observations from automatic weather stations on Thwaites Eastern Ice Shelf with the firn model SNOWPACK and interferometric reflectometry (IR) to examine a case study of three ARs that made landfall in rapid succession from 2 to 8 February 2020, known as an AR family event. While accumulation dominates the surface impacts of the event on Thwaites Eastern Ice Shelf (> 100 kg m−2 or millimeters water equivalent), we find small amounts of surface melt as well (< 5 kg m−2). The results presented here enable us to quantify the past impacts of ARs on West Antarctica's surface mass balance (SMB) and characterize their interannual variability and trends, enabling a better assessment of future AR-driven changes in the SMB.

54 ENVIRONMENTAL SCIENCES↗

Reach performance while wearing the Space Shuttle launch and entry suit during exposure to launch accelerations

Crewmen aboard the Space Shuttle are subjected to accelerations during ascent (the powered flight phase of launch) which range up to +3 G(sub x). Despite having 33 missions and nine years experience, not to mention all the time spent in development prior to the first flight, no truly quantitative reach study wearing actual crew equipment, using actual Shuttle seats and restraints has ever been done. What little information exists on reach performance while under acceleration has been derived primarily from subjective comments gathered retrospectively from Shuttle flight crews during their post mission debrief. This lack of reach performance data has resulted in uncertainty regarding emergency procedures that can realistically be performed during and actual Shuttle ascent versus what is practiced in the ground-fixed and motion-based Shuttle Simulators. With the introduction on STS-26 of the current Shuttle escape system, the question of reach performance under launch accelerations was once again raised. The escape system's requirement that each crewman wear a Launch/Entry Suit (LES), parachute harness, and parachute were all anticipated to contribute to a further degradation of reach performance during Shuttle ascent accelerations. In order to answer the reach performance question in a quantitative way, a photogrammetric method was chosen so that the actual reach values and associated envelopes could be captured. This would allow quantitative assessment of potential task performance impact and identify areas where changes to our Shuttle ascent emergency procedures might be required. Also, such a set of reach values would be valid for any similar acceleration profile using the same crew equipment. Potential Space Station applications of this data include predicting reach performance during Assured Crew Return Vehicle (ACRV) operations.

Bagian, James P.↗

Semi-Empirical Validation of the Cross-Band Relative Absorption Technique for the Measurement of Molecular Mixing Ratios

Studies were performed to carry out semi-empirical validation of a new measurement approach we propose for molecular mixing ratios determination. The approach is based on relative measurements in bands of O2 and other molecules and as such may be best described as cross band relative absorption (CoBRA). . The current validation studies rely upon well verified and established theoretical and experimental databases, satellite data assimilations and modeling codes such as HITRAN, line-by-line radiative transfer model (LBLRTM), and the modern-era retrospective analysis for research and applications (MERRA). The approach holds promise for atmospheric mixing ratio measurements of CO2 and a variety of other molecules currently under investigation for several future satellite lidar missions. One of the advantages of the method is a significant reduction of the temperature sensitivity uncertainties which is illustrated with application to the ASCENDS mission for the measurement of CO2 mixing ratios (XCO2). Additional advantages of the method include the possibility to closely match cross-band weighting function combinations which is harder to achieve using conventional differential absorption techniques and the potential for additional corrections for water vapor and other interferences without using the data from numerical weather prediction (NWP) models.

Pliutau, Denis↗

Studying Diurnal Variations of Aerosols with NASA MERRA-2 Reanalysis Data

Aerosols play an important role in atmospheric dynamics, climate variations, and Earth's energy cycle by altering the radiation balance in the atmosphere through interaction with clouds, providing fertilizer for forests and canopy, and as a supply of iron to the ocean over long time periods. Studies suggest that much of the feedback between dust aerosols and dynamics is associated with diurnal and synoptic scale variability. However, the lack of sub-daily resolution of aerosols from satellite observations makes it difficult to study the diurnal characteristics, especially over tropical and subtropical regions. Investigation of this topic utilizes over 37 years of simulated global aerosol products from NASA atmospheric reanalysis, in the second Modern-Era Retrospective analysis for Research and Applications (MERRA-2) data set, available from NASA Goddard Earth Science Data and Information Services Center (GES DISC). MERRA-2 covers the period 1980-present, and is continuing as an ongoing climate analysis. Aerosol assimilation is included throughout the period, using data from MODIS, MISR, AERONET, and AVHRR (in the pre-EOS period). The aerosols are assimilated using the MERRA-2 aerosol model, which interacts directly with radiation parameterization, and is radiatively coupled with atmospheric model dynamics in the Goddard Earth Observing System Model, Version 5 (GEOS-5). Hourly, monthly, and monthly diurnal data are available at spatial resolution of 0.5o x 0.625o (latitude x longitude). By using MERRA-2 hourly and monthly diurnal products, different aerosol diurnal variabilities are observed over North America, Africa, Asia, and Australia, that may be due to different meteorological conditions and aerosol sources. The presentation will also provide an overview of MERRA-2 data services at GES DISC, such as how to find and download data, and how to quickly visualize and analyze data online with Giovanni.

aerosol↗

Causes of Interannual Variability over the Southern Hemispheric Tropospheric Ozone Maximum

We examine the relative contribution of processes controlling the interannual variability (IAV) of tropospheric ozone over four sub-regions of the southern hemispheric tropospheric ozone maximum (SHTOM) over a 20-year period. Our study is based on hindcast simulations from the National Aeronautics and Space Administration Global Modeling Initiative chemistry transport model (NASA GMI-CTM) of tropospheric and stratospheric chemistry, driven by assimilated Modern Era Retrospective Analysis for Research and Applications (MERRA) meteorological fields. Our analysis shows that over SHTOM region, the IAV of the stratospheric contribution is the most important factor driving the IAV of upper tropospheric ozone (270 hectopascals), where ozone has a strong radiative effect. Over the South Atlantic region, the contribution from surface emissions to the IAV of ozone exceeds that from stratospheric input at and below 430 hectopascals. Over the South Indian Ocean, the IAV of stratospheric ozone makes the largest contribution to the IAV of ozone with little or no influence from surface emissions at 270 and 430 hectopascals in austral winter. Over the tropical South Atlantic region, the contribution from IAV of stratospheric input dominates in austral winter at 270 hectopascals and drops to less than half but is still significant at 430 hectopascals. Emission contributions are not significant at these two levels. The IAV of lightning over this region also contributes to the IAV of ozone in September and December. Over the tropical southeastern Pacific, the contribution of the IAV of stratospheric input is significant at 270 and 430 hectopascals in austral winter, and emissions have little influence.

Global Modeling Initiative chemistry transport mod↗

Long-Term Ozone Variability and Trends from Reanalyses

Stratospheric ozone has a profound impact on radiation and chemistry over various spatial and temporal scales. The evolution of stratospheric ozone over the 21st century, however, is not well understood, especially in the lower stratosphere. Highly vertically resolved ozone data from satellite-borne limb sounders have proved to be invaluable for studying ozone in the middle and upper stratosphere but it was not until recently that these measurements were successfully incorporated in atmospheric reanalyses. Validation and comparison studies have demonstrated that the addition of observations from the Microwave Limb Sounder (MLS) on EOS (Earth Observing System) Aura greatly improved the quality of ozone fields in MERRA-2 (Modern-Era Retrospective analysis for Research and Applications, Version 2) making these assimilated data sets more useful for scientific research. In this presentation we demonstrate that multidecadal lower-stratospheric ozone variability and trends can be derived from NASA's MERRA-2 reanalysis ozone. In particular, the reanalysis ozone bias-corrected using a chemistry model simulation as a transfer function agrees very well with recently reprocessed long ozonesonde records. Ozone trends in the lower stratosphere will be discussed in the context of recent findings (Ball et al., 2018) and interpreted in connection with long-term circulation changes in the lower stratosphere. Next, we show that the use of ozone data retrieved from the next generation OMPS (Ozone Mapping Profiler Suite) instruments, including the OMPS Limb Profiler, can successfully extend the reanalyses into the future allowing comprehensive monitoring of global ozone and interpretation of its evolution during the critical period of expected ozone recovery and climate change from increasing concentration of greenhouse gases.

ozone↗

Seasonal Variation of the Quasi-Biennial Oscillation Descent

This study examines variations through the year in the rate of descent of the Quasi-Biennial Oscillation (QBO) wind in the tropical lower stratosphere. The work is based on the Modern-Era Retrospective analysis for Research and Applications, Version 2 (MERRA-2) multi-year global reanalysis. A 10-member ensemble of free-running atmospheric simulations using the Global Earth Observing System (GEOS) atmospheric general circulation model is also examined. The QBO winds are decomposed into two orthogonal modes that describe amplitude and phase propagation. This reveals a semi-annual signal in descent rate, with slow descent at times of large middle-latitude planetary wave activity, suggesting that this wave activity influences equatorial vertical velocity. This result also explains the suppression of QBO wind transitions during active wave times. Results also show a variation in descent speed when plotted against QBO phase. These results provide a baseline of QBO behavior for future QBO modeling.

Quasi-biennial oscillation↗

A Ground-Based Network for Improved Validation of Satellite Carbon Dioxide and Methane Observations Over the Eastern United States

Satellite observations of greenhouse gases (GHGs), notably carbon dioxide and methane, over the Eastern United States, are currently only validated indirectly and/or sporadically. There are only four existing routine, ground-based remote sensing locations in the United States suitable for validation of satellite GHG observations: Edwards and Pasadena, CA, Lamont, OK, and Park Falls, WI as part of the Total Carbon Column Observing Network (TCCON). Among other efforts, e.g. the Network for the Detection of Atmospheric Composition Change (NDACC) and EM27/SUN deployments led by the University of Toronto, the only sites west of the Mississippi River are Park Falls, WI and Toronto, ON. The only remaining validation tools, vicarious calibration and airborne campaigns, are sporadic in space and/or time and thus coincide with only a small subsample of available soundings and conditions. As a result, satellite GHG observations over the east coast of the United States, home to more than half of its population, lack a consistent, widespread means of validation. We describe an ongoing effort to position 8 EM27/SUN spectrometers along the Eastern Seaboard over the next two years. The goals of this effort are to improve both satellite validation and our understanding of human and natural influences on the carbon cycle of the Eastern US, the former enabling the latter. This work is intended to augment past, ongoing, and future inter-agency programs, e.g., the NIST Urban Testbed, routine aircraft and aircore sampling by NOAA, and NASA’s Atmospheric Carbon and Transport (ACT)-America sub-orbital campaign, in particular by offering information on broader time and spatial scales than what is already available while maintaining the high-accuracy constraints of in situ data. We will present early analysis including siting considerations to capture local and/or background conditions and comparison to NASA’s Goddard Earth Observing System (GEOS) modeling and assimilation systems. This includes a 40-day, 3-km horizontal resolution global simulation of early 2020 and a 50-km retrospective analysis of Orbiting Carbon Observatory 2 (OCO-2) observations over 2015-present. Both are valuable tools for analyzing expected and observed signals and are useful boundary conditions for yet higher-resolution studies.

Brad Weir↗

NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation

In this study, we explored the regulatory effects of nitrogen permease regulator 2-like (NPRL2) on niraparib sensitivity, a PARP inhibitor (PARPi) in castrate-resistant prostate cancer (CRPC). Data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) program were retrospectively examined. Gene-set enrichment analysis (GSEA) was conducted between high and low NRPL2 expression prostate adenocarcinoma (PRAD) cases in TCGA. CCK-8 assay, Western blot analysis of apoptotic proteins, and flow cytometric analysis of apoptosis were applied to test niraparib sensitivity. Immunofluorescent (IF) staining and co-immunoprecipitation (co-IP) were conducted to explore the proteins interacting with NPRL2. Results showed that the upregulation of a canonical protein-coding transcript of NPRL2 (ENST00000232501.7) is associated with an unfavorable prognosis. Bioinformatic analysis predicts a physical interaction between NPRL2 and UBE2M, which is validated by a following Co-IP assay. This interaction increases NPRL2 stability by reducing polyubiquitination and proteasomal degradation. Depletion of NPRL2 or UBE2M significantly increases the niraparib sensitivity of CRPC cells and enhances niraparib-induced tumor growth inhibition in vivo. NPRL2 cooperatively enhances UBE2M-mediated neddylation and facilitates the degradation of multiple substrates of Cullin-RING E3 ubiquitin ligases (CRLs). In conclusion, this study identified a novel NPRL2-UBE2M complex in modulating neddylation and niraparib sensitivity of CRPC cells. Therefore, targeting NPRL2 might be considered as an adjuvant strategy for PARPi therapy.

60 APPLIED LIFE SCIENCES↗

The Impact of Radiation Therapy in Children and Adolescents With Metastatic Rhabdomyosarcoma

There is limited evidence to define the role of radiation therapy in children with metastatic rhabdomyosarcoma (mRMS). In the international BERNIE study, children with mRMS or non-RMS soft tissue sarcoma were randomized to receive standard chemotherapy with or without bevacizumab, with radiation therapy to all disease sites recommended after chemotherapy cycle 6. We retrospectively evaluated the impact of radiation therapy on survival in the mRMS cohort.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Reservoir Thermal Energy Storage Benchmarking (Rev. 3)

A benchmarking analysis of RTES research funded by GTO through the Beyond Batteries projects was conducted against the ESGC to see where they fit within the identified ESGC Use Cases. The projects were found to advance knowledge in multiple ESGC use cases, either directly or in some cases, indirectly as enabling technologies. This analysis is helpful to understand where RTES and associated research fits into the larger discussion around energy storage technologies. Also, a retrospective analysis of the Beyond Batteries projects was conducted to evaluate what the projects learned and how the results can be applied to advance the value of RTES. Major results of each of the studies are summarized in Table 2. Additionally, a comparative metrics analysis for RTES was completed to understand where RTES lies within the energy storage industry. Metrics for evaluation of RTES and its comparison to other storage technologies were selected and ranges of their values compiled. The selected metrics – LCOE (levelized cost of energy), capital costs, roundtrip efficiency, energy storage capacity, and storage time – were chosen based on data availability and have a particularly strong influence on the potential deployment of a storage technology. Charts which compare the metrics are presented in section 4.3 and show ranges for each of the 10 selected technologies. However, due to a lack of domestic operational facilities, values for RTES and for portions of the remaining technologies are based on theoretical modeling and studies of best-case scenarios. LCOE estimates for RTES fall within the lower reaches of Figure 15, but nevertheless amount to 2 – 5 times the ESGC Roadmap goal for LCOE, for example in the Facilitating and Evolving Grid Use Case. Capital costs for RTES sit on the higher end (Figure 16) but are expected to decrease as new projects are developed and the technology is refined. The theoretical roundtrip efficiency reported for RTES varies from mid to high percentages (Figure 17) with efficiencies upwards of 93% in modeled scenarios in the Portland Basin (Bershaw et al.,2020). RTES is also expected to have the largest energy storage capacities and longest storage times, likely matched only by lower efficiency hydrogen storage. To better assess the role that RTES could play in energy storage we examined it’s potential in the U.S. The potential depends on many factors. Recently, many researchers have started looking at deep sedimentary basins, depleted oil and gas fields, and basalt formations as potential targets for RTES development. The United States Geological Survey (USGS) has analyzed various cities and shown substantial RTES potential in the cooling sector (Pepin et al., 2021). By modeling RTES in low-quality groundwater (e.g., brackish), it is shown to be favorable across the U.S. with particular suitability in the Illinois Basin, Coastal Plains, and Basin and Range regions. Seasonal RTES operations have also been modeled in the Portland Basin by those at the USGS and Portland State University to simulate an RTES system supplying heating loads needed for the Oregon Health and Science University. Simulations suggest that high conductive heat loss in the initial years exists but tends to decrease with increasing time and development of the resource due to self-insulating nature of the basalts (Burns et al., 2020). Other national laboratory efforts are taking a close look at many of the technical issues involved with RTES (McLing et al., 2019, McLing et al., 2022). These include difficulties in understanding geochemical, hydrogeological, mechanical, and microbiological changes at such elevated temperatures and operational scenarios. Major gaps in research are identified and suggested for future work. With this increased focus to understand how to make RTES successful in the U.S., this technology could be a potential solution to many of the nation’s energy storage problems. For the energy independence of this country, the DOE should prioritize de-risking this technology by making future investments in pilot-scale demonstrations to attract potential investors.

15 GEOTHERMAL ENERGY↗

Understanding processes that control dust spatial distributions with global climate models and satellite observations

Dust aerosol is important in modulating the climate system at local and global scales, yet its spatiotemporal distributions simulated by global climate models (GCMs) are highly uncertain. In this study, we evaluate the spatiotemporal variations of dust extinction profiles and dust optical depth (DOD) simulated by the Community Earth System Model version 1 (CESM1) and version 2 (CESM2), the Energy Exascale Earth System Model version 1 (E3SMv1), and the Modern-Era Retrospective analysis for Research and Applications version 2 (MERRA-2) against satellite retrievals from Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP), Moderate Resolution Imaging Spectroradiometer (MODIS), and Multi-angle Imaging SpectroRadiometer (MISR). We find that CESM1, CESM2, and E3SMv1 underestimate dust transport to remote regions. E3SMv1 performs better than CESM1 and CESM2 in simulating dust transport and the northern hemispheric DOD due to its higher mass fraction of fine dust. CESM2 performs the worst in the Northern Hemisphere due to its lower dust emission than in the other two models but has a better dust simulation over the Southern Ocean due to the overestimation of dust emission in the Southern Hemisphere. DOD from MERRA-2 agrees well with CALIOP DOD in remote regions due to its higher mass fraction of fine dust and the assimilation of aerosol optical depth. The large disagreements in the dust extinction profiles and DOD among CALIOP, MODIS, and MISR retrievals make the model evaluation of dust spatial distributions challenging. Our study indicates the importance of representing dust emission, dry/wet deposition, and size distribution in GCMs in correctly simulating dust spatiotemporal distributions.

54 ENVIRONMENTAL SCIENCES↗

Apollo: A Retrospective Analysis

The program to land an American on the Moon and return safely to Earth in the 1960s has been called by some observers a defining event of the twentieth century. Pulitzer Prize-winning historian Arthur M. Schlesinger, Jr., even suggested that when Americans two centuries hence study the twentieth century, they will view the Apollo lunar landing as the critical event of the century. While that conclusion might be premature, there can be little doubt but that the flight of Apollo 11 in particular and the overall Apollo program in general was a high point in humanity s quest to explore the universe beyond Earth. Since the completion of Project Apollo more than twenty years ago there have been a plethora of books, studies, reports, and articles about its origin, execution, and meaning. At the time of the twenty-fifth anniversary of the first landing, it is appropriate to reflect on the effort and its place in U.S. and NASA history. This monograph has been written as a means to this end. It presents a short narrative account of Apollo from its origin through its assessment. That is followed by a mission by mission summary of the Apollo flights and concluded by a series of key documents relative to the program reproduced in facsimile. The intent of this monograph is to provide a basic history along with primary documents that may be useful to NASA personnel and others desiring information about Apollo.

Launius, Roger D.↗

Recent Pharmacology Studies on the International Space Station

The environment on the International Space Station (ISS) includes a variety of potential stressors including the absence of Earth's gravity, elevated exposure to radiation, confined living and working quarters, a heavy workload, and high public visibility. The effects of this extreme environment on pharmacokinetics, pharmacodynamics, and even on stored medication doses, are not yet understood. Dr. Wotring will discuss recent analyses of medication doses that experienced long duration storage on the ISS and a recent retrospective examination of medication use during long‐duration spaceflights. She will also describe new pharmacology experiments that are scheduled for upcoming ISS missions. Dr. Virginia E. Wotring is a Senior Scientist in the Division of Space Life Sciences in the Universities Space Research Association, and Pharmacology Discipline Lead at NASA's Johnson Space Center, Human Heath and Countermeasures Division. She received her doctorate in Pharmacological and Physiological Science from Saint Louis University after earning a B.S. in Chemistry at Florida State University. She has published multiple studies on ligand gated ion channels in the brain and spinal cord. Her research experience includes drug mechanisms of action, drug receptor structure/function relationships and gene & protein expression. She joined USRA (and spaceflight research) in 2009. In 2012, her book reviewing pharmacology in spaceflight was published by Springer: Space Pharmacology, Space Development Series.

Wotring, Virginia↗

Crew Factors in Flight Operations: A Survey of Fatigue Factors in Corporate/Executive A Viation Operations - 8

Corporate flight crews face unique challenges including unscheduled flights, quickly changing schedules, extended duty days, long waits, time zone changes, and peripheral tasks. Most corporate operations are regulated by Part 91 FARs which set no flight or duty time limits. The objective of this study was to identify operationally significant factors that may influence fatigue, alertness, and performance in corporate operations. In collaboration with the National Business Aircraft Association and the Flight Safety Foundation, NASA developed and distributed a retrospective survey comprising 107 questions addressing demographics, home sleep habits, flight experience, duty schedules, fatigue during operations, and work environment. Corporate crewmembers returned 1,488 surveys. Respondents averaged 45.2 years of age, had 14.9 years of corporate flying experience, and 9,750 total flight hours. The majority (89%) rated themselves as 'good' or 'very good' sleepers at home. Most (82%) indicated they are subject to call for duty and described an average duty day of 9.9 h. About two-thirds reported having a daily duty time limit and over half (57%) reported a daily flight time limit. Nearly three-quarters (71%) acknowledged having 'nodded off' during a flight. Only 21% reported that their flight departments offer training on fatigue issues. Almost three-quarters (74%) described fatigue as a 'moderate' or 'serious' concern, and a majority (61%) characterized it as a common occurrence. Most (85%) identified fatigue as a 'moderate' or 'serious' safety issue.

Rosekind, Mark R.↗