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DOE OSTI2025

5G-TSN Architecture Capable of Providing Real-time Situational Awareness to Fossil-Energy (FE) Generation Systems (Final Technical Report)

This final report highlights the comprehensive achievements of the project focused on developing and validating a 5G-Time Sensitive Networking (TSN) architecture tailored for real-time operational awareness in fossil energy systems. The initiative successfully advanced through a series of technical milestones, including the integration of EMI-aware network models, deployment of advanced simulation frameworks, and real-world performance characterization at key sites such as UTEP and Fabens. Through the strategic use of NetSim® software, the team created and validated network configurations for wired and wireless environments, tested under varying congestion conditions, and verified network slicing implementations for URLLC-specific applications. Major accomplishments include the migration of simulation tools to the latest NetSim® version to support accurate modeling of TSN and network slicing, extensive EMI measurement campaigns, and the development of a robust simulation model for end-to-end SCADA system integration. Simulations compared both TDD and FDD duplexing modes, revealing insights into their performance under congested conditions. The wireless network was benchmarked for throughput, jitter, and delay metrics, aligning with 3GPP Release 15/16 and IEEE 802.1-TSN standards. A peer-reviewed conference paper was accepted and published, contributing to the broader academic and industrial discourse on 5G-TSN integration in energy systems, in addition to a journal article. Despite minor delays due to software limitations, the project achieved its objectives and delivered validated architecture ready for deployment in advanced energy network environments.

01 COAL, LIGNITE, AND PEAT↗

NASA NTRS1995

GASCan 2 payload integration

This project, conducted in cooperation with the NASA Advanced Space Design Program, is part of an ongoing effort to place an experiment package into space. The goal of this project is to build and test flight-ready hardware that can be launched from the Space Shuttle. Get Away Special Canister 2 (GASCan 2) consists of three separate experiments. The Ionospheric Properties and Propagation Experiment (IPPE) determines effects of the ionosphere on radio wave propagation. The Microgravity Ignition experiment (MGI) tests the effects of combustion in a microgravity environment. The Rotational Fluid Flow experiment (RFF) examines fluid behavior under varying levels of gravity. This year the following tasks were completed: design of the IPPE antenna, X- and J-cell battery boxes, J-cell battery box enclosure, and structural bumpers; construction of the MGI canisters, MGI mounting brackets, IPPE antenna, and battery boxes; and the selection of the RFF's operating fluid and the analysis of the fluid behavior under microgravity test conditions.

Cody, Dennis J.↗

NASA NTRS2002

Stirling Research Laboratory Providing Independent Performance Verification of Convertors for a Stirling Radioisotope Generator

The Department of Energy (DOE), Germantown, Maryland, Stirling Technology Company (STC), Kennewick, Washington, and NASA Glenn Research Center are developing a free-piston Stirling convertor for a high-efficiency Stirling Radioisotope Generator for NASA Space Science missions. This generator is being developed for multimission use, including providing electric power for unmanned Mars rovers and for deep space missions. STC is developing the 55-W Technology Demonstration Convertor (TDC) under contract to DOE. Glenn is conducting an in-house technology project to assist in developing the convertor for readiness for space qualification and mission implementation. As part of this effort, a Stirling Research Laboratory was established to test the TDC's and related technologies. A key task is providing an independent verification and validation of the TDC performance. Four TDC's are now being tested at Glenn. Acceptance testing has been completed for all convertors, and in general, performance agreed well with that achieved by STC prior to the delivery of the convertors. Performance mapping has also been completed on two of the convertors over a range of hot-end temperatures (450 to 650 C), cold-end temperatures (80 to 120 C), and piston amplitudes (5.2 to 6.2 mm). These test data are available online at http://www.grc.nasa.gov/WWW/tmsb/. The TDC's can be tested in either a horizontal orientation with dual-opposed convertors or in a vertical orientation with a single convertor. Synchronized dual-opposed pairs are used for dynamically balanced operation that results in very low levels of vibration. The Stirling Research Laboratory also supports launch environment testing of the TDC's in Glenn's Structural Dynamics Laboratory and electromagnetic interference and electromagnetic compatibility characterization and reduction efforts. In addition, the TDC's will be used for long-term endurance testing, and preparations are underway for unattended operation.

Thieme, Lanny G.↗

NASA NTRS2009

An Impact Sensor System for the Characterization of the Micrometeoroid and Lunar Secondary Ejecta Environment

The Impact Sensor for Micrometeoroid and Lunar Secondary Ejecta (IMMUSE) project aims to apply and integrate previously demonstrated impact sensing subsystems to characterize the micrometeoroid and lunar secondary (MMSE) environment on the surface of the Moon. Once deployed, data returned from IMMUSE will benefit: (1) Fundamental Lunar Science: providing data to improve the understanding of lunar cratering processes and dynamics of the lunar regolith. (2) Lunar Exploration Applied Science: providing an accurate MMSE environment definition for reliable impact risk assessments, cost-effective shielding designs, and mitigation measures for long-term lunar exploration activities. (3) Planetary Science: providing micrometeoroid data to aid the understanding of asteroidal collisions and the evolution of comets. A well-established link between micrometeoroid impacts and lunar regolith is also key to understanding other regolith-covered bodies from remote-sensing data. The IMMUSE system includes two components: (1) a large area (greater than or equal to 1 m2) micrometeoroid detector based on acoustic impact and fiber optic displacement sensors and (2) a 100 cm2 lunar secondary ejecta detector consisting of dual-layer laser curtain and acoustic impact sensors. The combinations of different detection mechanisms will allow for a better characterization of the MMSE environment, including flux, particle size/mass, and impact velocity. IMMUSE is funded by the NASA LASER Program through 2012. The project fs goal is to reach a Technical Readiness Level of 4 in preparation for a more advanced development beyond 2012. Several prototype subsystems have been constructed and subjected to low impact and hypervelocity impact tests. The presentation will include a status review and preliminary test results.

Liou, J.-C.↗

NASA NTRS2009

CERES FM-5 on the NPP Spacecraft: Continuing the Earth Radiation Budget Climate Data Record

The Clouds and the Earth's Radiant Energy System (CERES) Flight Model-5 (FM-5) instrument will fly on the NPOESS Preparatory Project (NPP) spacecraft, which has a launch-readiness date in June, 2010. This mission will continue the critical Earth Radiation Budget Climate Data Record (CDR) begun by the Earth Radiation Budget Experiment (ERBE) instruments in the mid 1980 s and continued by the CERES instruments currently flying on the EOS Terra and Aqua spacecraft. Ground calibrations have been completed for FM-5 and the instrument has been delivered for integration to the spacecraft Rigorous pre-launch ground calibration is performed on each CERES unit to achieve an accuracy goal of 1% for SW flux and 0.5% for outgoing LW flux. Any ground to flight or in-flight changes in radiometer response is monitored using a protocol employing both onboard and vicarious calibration sources and experiments. Recent studies of FM-1 through FM-4 data have shown that the SW response of space based broadband radiometers can change dramatically due to optical contamination. With these changes having most impact on optical response to blue-to UV radiance, where tungsten lamps are largely devoid of output, such changes are hard to monitor accurately using existing on-board sources. This paper outlines the lessons learned on the existing CERES sensors from 30+ years of flight experience and presents a radiometric protocol to be implemented on the FM-5 instrument to ensure that its performance exceeds the stated calibration and stability goals.

Priestly, Kory↗

NASA NTRS2012

CHARM: A CubeSat Water Vapor Radiometer for Earth Science

The Jet Propulsion Laboratory (JPL) and Ames Research Center (ARC) are partnering in the CubeSat Hydrometric Atmospheric Radiometer Mission (CHARM), a water vapor radiometer integrated on a 3U CubeSat platform, selected for implementation under NASA Hands-On Project Experience (HOPE-3). CHARM will measure 4 channels at 183 GHz water vapor line, subsets of measurements currently performed by larger and more costly spacecraft (e.g. ATMS, AMSU-B and SSMI/S). While flying a payload that supports SMD science objectives, CHARM provides a hands-on opportunity to develop technical, leadership, and project skills. CHARM will furthermore advance the technology readiness level (TRL) of the 183 GHz receiver subsystem from TRL 4 to TRL 6 and the CubeSat 183 GHz radiometer system from TRL 4 to TRL 7.

Monolithic microwave integrated circuits (MMICs)↗

NASA NTRS2014

Recent Successes and Future Plans for NASA's Space Communications and Navigation Testbed on the International Space Station

Flexible and extensible space communications architectures and technology are essential to enable future space exploration and science activities. NASA has championed the development of the Space Telecommunications Radio System (STRS) software defined radio (SDR) standard and the application of SDR technology to reduce the costs and risks of using SDRs for space missions, and has developed an on-orbit testbed to validate these capabilities. The Space Communications and Navigation (SCaN) Testbed (previously known as the Communications, Navigation, and Networking reConfigurable Testbed (CoNNeCT)) is advancing SDR, on-board networking, and navigation technologies by conducting space experiments aboard the International Space Station. During its first year(s) on-orbit, the SCaN Testbed has achieved considerable accomplishments to better understand SDRs and their applications. The SDR platforms and software waveforms on each SDR have over 1500 hours of operation and are performing as designed. The Ka-band SDR on the SCaN Testbed is NASAs first space Ka-band transceiver and is NASA's first Ka-band mission using the Space Network. This has provided exciting opportunities to operate at Ka-band and assist with on-orbit tests of NASA newest Tracking and Data Relay Satellites (TDRS). During its first year, SCaN Testbed completed its first on-orbit SDR reconfigurations. SDR reconfigurations occur when implementing new waveforms on an SDR. SDR reconfigurations allow a radio to change minor parameters, such as data rate, or complete functionality. New waveforms which provide new capability and are reusable across different missions provide long term value for reconfigurable platforms such as SDRs. The STRS Standard provides guidelines for new waveform development by third parties. Waveform development by organizations other than the platform provider offers NASA the ability to develop waveforms itself and reduce its dependence and costs on the platform developer. Each of these new waveforms requires a waveform build environment for the particular SDR, helps assess the usefulness of the platform provider documentation, and exercises the objectives of STRS Standard and the SCaN Testbed. There is considerable interest in conducting experiments using the SCaN Testbed from NASA, academia, commercial companies, and other space agencies. There are approximately 25 experiments or activities supported by the project underway or in development, with more proposals ready, as time and funding allow, and new experiment solicitations available. NASA continues development of new waveforms and applications in communications, networking, and navigation, the first university experimenters are beginning waveform development, which will support the next generation of communications engineers, and international interest is beginning with space agency partners from European Space Agency (ESA) and the Centre National d'Etudes Spatiales (CNES). This paper will provide an overview of the SCaN Testbed and discuss its recent accomplishments and experiment activities.Its recent successes in Ka-band operations, reception of the newest GPS signals, SDR reconfigurations, and STRS demonstration in space when combined with the future experiment portfolio have positioned the SCaN Testbed to enable future space communications and navigation capabilities for exploration and science.

SOFTWARE DEFINED RADIO↗

NASA NTRS2017

NASA's Kilopower Reactor Development and the Path to Higher Power Missions

The development of NASAs Kilopower fission reactor is taking large strides toward flight development with several successful tests completed during its technology demonstration trials. The Kilopower reactors are designed to provide 1-10 kW of electrical power to a spacecraft which could be used for additional science instruments as well as the ability to power electric propulsion systems. Power rich nuclear missions have been excluded from NASA proposals because of the lack of radioisotope fuel and the absence of a flight qualified fission system. NASA has partnered with the Department of Energy's National Nuclear Security Administration to develop the Kilopower reactor using existing facilities and infrastructure to determine if the design is ready for flight development. The 3-year Kilopower project started in 2015 with a challenging goal of building and testing a full-scale flight prototypic nuclear reactor by the end of 2017. As the date approaches, the engineering team shares information on the progress of the technology as well as the enabling capabilities it provides for science and human exploration.

Kilopower↗

NASA NTRS2017

NASA's Kilopower Reactor Development and the Path to Higher Power Missions

The development of NASA's Kilopower fission reactor is taking large strides toward flight development with several successful tests completed during its technology demonstration trials. The Kilopower reactors are designed to provide 1-10 kW of electrical power to a spacecraft which could be used for additional science instruments as well as the ability to power electric propulsion systems. Power rich nuclear missions have been excluded from NASA proposals because of the lack of radioisotope fuel and the absence of a flight qualified fission system. NASA has partnered with the Department of Energy's National Nuclear Security Administration to develop the Kilopower reactor using existing facilities and infrastructure to determine if the design is ready for flight development. The 3-year Kilopower project started in 2015 with a challenging goal of building and testing a full-scale flight prototypic nuclear reactor by the end of 2017. As the date approaches, the engineering team shares information on the progress of the technology as well as the enabling capabilities it provides for science and human exploration.

Kilopower↗

NASA NTRSDate not supplied

Status and Predicted Performance for the AstroPIC Integrated Photonic Coronagraph

Integrated photonics is a promising coronagraph technology option for exoplanet-imaging missions like NASA’s Habitable Worlds Observatory flagship. It is theoretically capable of achieving better performance than traditional bulk-optic coronagraphs because arrays of integrated interferometers can be combined to implement any linear operator. However, photonic coronagraphs require significant maturation to be ready for a space telescope mission. The AstroPIC project is advancing this technology by developing a proof-of-concept integrated photonic coronagraph based on silicon photonic integrated circuit (PIC) technology. Specifically, the AstroPIC program is investigating the impact of a PIC coronagraph on the predicted scientific yield of the upcoming Habitable Worlds Observatory (HWO) mission concept. In this talk, we will present the current status of the AstroPIC design, including the layout of the most recent PIC. We will also present on the status of simulations that predict the performance of the instrument and feed into scientific yield estimations for HWO Exoploratory Analytic Cases (EACs) 1-3. Finally, we will present the status of the development of a PIC testbed at NASA Ames and results from preliminary PIC laboratory testing at Stanford.

Photonics↗

DOE OSTI2016

Regulation of the Shutdown Defueling and Decommissioning Reactors in the United Kingdom - 16576

Nuclear policy, including for decommissioning, in the United Kingdom is set by the UK Government. The Nuclear Decommissioning Authority, NDA, is responsible for managing the clean-up of the UK's nuclear legacy which includes the first generation of Magnox power stations. Magnox Ltd (MXL), owned by Cavendish Fluor Partnership, is the licensee and the management and operations contractor responsible for ten Magnox reactor sites and two restoration sites in the UK, working for the sites' owner, NDA. The work of the company is diverse covering electricity generation at Wylfa (until December 2015), defueling, and preparation for an interim end state, known as Care and Maintenance (C and M) which will precede the final site clearance. The C and M phase is expected to last over 75 years during which the sites are maintained in a passively safe and secure state while radiation levels are left to decay naturally. Preparations for this phase include removing fuel from the reactors and storage ponds; retrieving intermediate level waste from current stores and treating it or converting it to forms suitable for long-term storage or disposal and making sure of the integrity of critical safety systems of the de-fuelled reactors. The Decommissioning, Fuel and Waste programme within the Office for Nuclear Regulation, ONR, regulates nuclear safety in the 12 Magnox nuclear licensed sites. ONR works with the environmental regulators who are responsible for environmental protection on nuclear sites. The focus of this paper is the regulation of nuclear safety by ONR across the Magnox sites and the interactions with nuclear security and the environmental aspects required to achieve effective, proportionate and efficient regulation of these sites in the UK. ONR's strategy for regulating the Magnox defueling and decommissioning sites is focused on enabling the licensee to complete the initial stages of decommissioning and reduce the nuclear and radioactive hazards on its sites. To this effect, ONR's revised inspection guidance is centred on inspecting the (remaining) important systems for safety identified in the safety cases. Other interventions focus on engaging with the licensee on safety significant decommissioning projects to gain evidence of the licensee's readiness prior to and during these activities rather than formal assessment of the associated safety cases. In light of reduced hazards and risks across the de-fueled and decommissioning Magnox reactors, ONR's revised regulatory expectation regarding evolution of emergency arrangements during decommissioning is based on key transition points that follow electricity generation. Implementation of these revised strategies as well as organisational restructuring within the team responsible for regulation of the Magnox fleet has resulted in improved efficiency and consistency in regulatory approach whilst securing the required safety standards in managing decommissioning activities. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

NASA NTRS2014

System Administration Support/SWORDS G2

The Soldier-Warfighter Operationally Responsive Deployer for Space (SWORDS) rocket is a dedicated small satellite launcher that will minimize danger and complexity in order to allow soldiers in the field to put payloads of up to 25kg into orbit from the field. The SWORDSG2 project is the development of a model, simulation, and ultimately a working application that will control and monitor the cryogenic fluid delivery to the SWORDS rocket for testing purposes. To accomplish this, the project is using the programming language environment Gensym G2. The environment is an all-inclusive application that allows development, testing, modeling, and finally operation of the unique application through graphical and programmatic methods. In addition, observation of the current cryogenic fluid delivery system in the Kennedy Space Center Cry Lab has allowed me to gain valuable experience of fluid systems and propelant delivery that is valuable to our team when developing amd modeling our own system.The ultimate goal of having a test-ready application to show to the heads of the project, and demonstrating G2's capabilities, by late 2014 will require hard work and intense study and understanding of not only the programming aspect but also the physical phenomena we want to model, observe, and control.

cryogenic fluids↗

NASA NTRS2019

Continuously Improving Parametric Modeling with Historical Data on the ICESat-2 Mission

This paper delves into the details of the Joint Confidence Level (JCL) process performed for the Ice, Cloud, and Land Elevation Satellite (ICESat)-2 mission and how past performance was incorporated into subsequent JCL models to enable the project to continuously analyze potential slips to their launch readiness date (LRD). One year prior to the mission Preliminary Review (mPDR), the JCL model development process began. The first model was well received at the mPDR, held on October 10, 2012, and the input received by the Standing Review Board was incorporated into the model for the official data drop for key decision point (KDP)-C. The 70% JCL results of the October 2012 mPDR model forecast an LRD of February 2017 and associated cost of $830M. This result in 2012 immediately highlighted potential challenges with the project-planned LRD of July 2016. The year following the mPDR, the project had sustained a oneyear slip in the LRD due to problematic systems engineering requirement issues which impacted all project subsystems. This slip moved the project planned LRD from July 2016 to July 2017, an additional 5 months beyond the 2012 model’s 70% JCL result for the LRD of February 2017. As the project was quickly approaching the mission Critical Design Review (mCDR), the need for reliable JCL results increased significantly. The project held discussions on the JCL modeling process and focused on the input uncertainty distributions. Specifically, to identify the uncertainty distributions that the 2012 mPDR model would have needed to produce a 70% LRD result of July 2017. This led the project to compare multiple uncertainty distributions, and ultimately spurred the project to utilize uncertainty distributions that incorporated project past performance and historical data to forecast potential LRD slips. The revised results, created in 2014 and utilizing the new uncertainty distributions, showed that with 70% confidence, the ICESat-2 mission would launch in August 2018 with a cost of $1,044M. Today, ICESat-2 is scheduled to launch on September 15, 2018 with a project management (PM) agreement value of $1,056M. This illustrates how a JCL model can be continuously improved to produce valuable results for a project, even in cases of LRD delays. The primary reason for the ICESat-2 LRD delay is due to a laser failure on the primary instrument. Laser failure was one of the highest risk and uncertainty drivers within the JCL model. The project placed the most risk in this area of the model, and the model further identified the laser as the top risk driver and contributor to the LRD result. This further illustrates how a JCL can be used to predict and quantify possible issues on new technology missions.

Krygiel, Joseph↗

DOE OSTI2020

Kilopower Project: The KRUSTY Fission Power Experiment and Potential Missions

The Kilopower Project was initiated by NASA’s Space Technology Mission Directorate/Game Changing Development Program in fiscal year 2015 to demonstrate subsystem-level technology readiness of small space fission power in a relevant environment (Technology Readiness Level 5) for space science and human exploration power needs. The Kilopower Project centerpiece is the Kilowatt Reactor Using Stirling TechnologY (KRUSTY) test, which consists of the development and testing of a ground technology demonstrator of a 1-kW(electric)–class fission power system (FPS). The technologies to be developed and validated by KRUSTY are extensible to space FPSs from 1 to 10 kW(electric), which can enable modular surface FPSs for human exploration as well as higher-power future potential deep space science missions. The KRUSTY demonstration is cofunded by NASA and the U.S. Department of Energy National Nuclear Security Administration. The KRUSTY demonstration in the National Critical Experiment Research Center’s Device Assembly Facility was completed in the first quarter of 2018.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

NASA NTRS2020

Kilopower Project: The KRUSTY Fission Power Experiment and Potential Missions

Space nuclear reactor↗

DOE OSTI2019

FY 18 Status Report on the Computing Systems for the Yucca Mountain Project TSPA-LA Models and Inventory of Software used for Process Models

Sandia National Laboratories (SNL) continued evaluation of total system performance assessment (TSPA) computing systems for the previously considered Yucca Mountain Project (YMP). This was done to maintain the operational readiness of the computing infrastructure (computer hardware and software) and knowledge capability for total system performance assessment (TSPA) type analysis, as directed by the National Nuclear Security Administration (NNSA), DOE 2010. This work is a continuation of the ongoing readiness evaluation reported in Lee and Hadgu (2014), Hadgu et al. (2015) and Hadgu and Appel (2016), and Hadgu et al. (2017). The TSPA computing hardware (2014 server cluster -CL2014) and storage system described in Hadgu et al. (2015) were used for the current analysis. One floating license of Gold Sim with Versions 9.60.300, 10.5, 11.1 and 12.0 was installed on the cluster head node, and its distributed processing capability was mapped on the cluster processors. Other supporting software were tested and installed to support the TSPA-type analysis on the server cluster. The FY18 task included developing an inventory of software used for the Yucca Mountain Project process models and preliminary assessment of status of the software; enhancing security of the cluster and setting a backup system. The 2014 server cluster and supporting software systems are fully operational to support TSPA-LA type analysis.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

NASA NTRS2000

Update on the NASA GRC Stirling Technology Development Project

The Department of Energy, NASA Glenn Research Center (GRC), and Stirling Technology Company (STC) are developing a free-piston Stirling convertor for a Stirling radioisotope power system (SRPS) to provide spacecraft on-board electric power for NASA deep space missions. The SRPS has recently been identified for potential use on the Europa Orbiter and Solar Probe Space Science missions. Stirling is also now being considered for unmanned Mars rovers. NASA GRC is conducting an in-house project to assist in developing the Stirling convertor for readiness for space qualification and mission implementation. As part of this continuing effort, the Stirling convertor will be further characterized under launch environment random vibration testing, methods to reduce convertor electromagnetic interference (EMI) will be developed, and an independent performance verification will be completed. Convertor life assessment and permanent magnet aging characterization tasks are also underway. Substitute organic materials for the linear alternator and piston bearing coatings for use in a high radiation environment have been identified and have now been incorporated in Stirling convertors built by STC for GRC. Electromagnetic and thermal finite element analyses for the alternator are also being conducted. This paper discusses the recent results and status for this NASA GRC in-house project.

Thieme, Lanny G.↗

NASA NTRS2015

WetLab-2: Providing Quantitative PCR Capabilities on ISS

The objective of NASA Ames Research Centers WetLab-2 Project is to place on the ISS a system capable of conducting gene expression analysis via quantitative real-time PCR (qRT-PCR) of biological specimens sampled or cultured on orbit. The WetLab-2 system is capable of processing sample types ranging from microbial cultures to animal tissues dissected on-orbit. The project has developed a RNA preparation module that can lyse cells and extract RNA of sufficient quality and quantity for use as templates in qRT-PCR reactions. Our protocol has the advantage that it uses non-toxic chemicals, alcohols or other organics. The resulting RNA is transferred into a pipette and then dispensed into reaction tubes that contain all lyophilized reagents needed to perform qRT-PCR reactions. These reaction tubes are mounted on rotors to centrifuge the liquid to the reaction window of the tube using a cordless drill. System operations require simple and limited crew actions including syringe pushes, valve turns and pipette dispenses. The resulting process takes less than 30 min to have tubes ready for loading into the qRT-PCR unit.The project has selected a Commercial-Off-The-Shelf (COTS) qRT-PCR unit, the Cepheid SmartCycler, that will fly in its COTS configuration. The SmartCycler has a number of advantages including modular design (16 independent PCR modules), low power consumption, rapid thermal ramp times and four-color detection. The ability to detect up to four fluorescent channels will enable multiplex assays that can be used to normalize for RNA concentration and integrity, and to study multiple genes of interest in each module. The WetLab-2 system will have the capability to downlink data from the ISS to the ground after a completed run and to uplink new programs. The ability to conduct qRT-PCR on-orbit eliminates the confounding effects on gene expression of reentry stresses and shock acting on live cells and organisms or the concern of RNA degradation of fixed samples. The system can be used to validate terrestrial analyses of samples returned from ISS by providing on-orbit gene expression benchmarking prior to sample return. The ability to get on-orbit data will provide investigators with the opportunity to adjust experimental parameters in real time for subsequent trials, without the need for sample return and re-flight to sample multigenerational changes. The system can also be used for analysis of air, surface, water, and clinical samples to monitor environmental contaminants and crew health. The verification flight of the instrument is scheduled to launch on SpaceX-7 in June 2015. The WetLab-2 Project is supported by NASAs ISS Program at JSC, Code OZ.

ISS tools↗