Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “Conditional rate functions”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 271 records · Page 15
All sourcesNASA NTRSDOE OSTI
DOE OSTI2023

Analysis of tumor-immune functional responses in a mathematical model of neoantigen cancer vaccines

Cancer neoantigen vaccines have emerged as a promising approach to stimulating the immune system to fight cancer. We propose a simple model including key elements of cancer-immune interactions and conduct a phase plane analysis to understand the immunological mechanisms of cancer neoantigen vaccines. Analytical results are obtained for two widely used functional forms that represent the killing rate of tumor cells by immune cells: the law of mass action (LMA) and the dePillis-Radunskaya Law (LPR). Using the LMA, our results reveal that a slowly growing tumor can escape the immune surveillance and that there is a unique periodic solution. The LPR offers richer dynamics, in which tumor elimination and uncontrolled tumor growth are both present. We show that tumor elimination requires sufficient number of initial activated T cells in relationship to the malignant cells, which lends support to using the neoantigen cancer vaccine as an adjuvant therapy after the primary tumor is surgically removed or treated using radiotherapy. We also derive a sufficient condition for uncontrolled tumor growth under the assumption of the LPR. Here, the juxtaposition of analyses with these two different choices for the killing rate function highlights their importance on model behavior and biological implications, by which we hope to spur further theoretical and experimental work to understand mechanisms underlying different functional forms for the killing rate.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2017

Investigation of Silica-Supported Vanadium Oxide Catalysts by High-Field 51 V Magic-Angle Spinning NMR

Supported V2O5/SiO2 catalysts were studied using solid state 51V MAS NMR at a sample spinning rate of 36 kHz and at a magnetic field of 19.975 T for a better understanding of the coordination of the vanadium oxide as a function of environmental conditions . Structural transformations of the supported vanadium oxide species between the catalyst in the dehydrated state and hydrated state under an ambient environment were revisited to examine the degree of oligomerization and the effect of water. The experimental results indicate the existence of a single dehydrated surface vanadium oxide species that resonates at -675 ppm and two vanadium oxide species under ambient conditions that resonate at -566 and -610 ppm, respectively. No detectable structural difference was found as a function of vanadium oxide loading on SiO2 (3% V2O5/SiO2 and 8% V2O5/SiO2). Quantum chemistry simulations of the 51V NMR chemical shifts on predicted surface structures were used as an aide in understanding potential surface vanadium oxide species on the silica support. The results suggest the formation of isolated surface VO4 units for the dehydrated catalysts with the possibility of dimer and cyclic trimer presence. The absence of bridging V-O-V vibrations (~200-300 cm-1) in the Raman spectra [Gao et al. J. Phys. Chem. B 1998, 102, 10842-10852], however, indicates that the isolated surface VO4 sites are the dominant dehydrated surface vanadia species on silica. Upon exposure to water, hydrolysis of the bridging V-O-Si bonds is most likely responsible for the decreased electron shielding experienced by vanadium. No indicators for the presence of hydrated decavanadate clusters or hydrated vanadia gels previously proposed in the literature were detected in this study.

Environmental Molecular Sciences Laboratory↗
DOE OSTI2015

Monitoring the Intensity of Ice Formation on Overhead Electric Power Lines and Contact Networks

The conditions for ice to form on a conductor are explained. A hypothesis on the existence of a functional relation between the rate of growth of a mass deposited on a non-live conductor, the dew and desublimation points, and the temperature of the wire surface when there is no wind is suggested and proved. Equations for determining the density, maximum possible mass of the coating and the intensity with which they are formed are proposed, which take into account the temperature of the conductor, the temperature and humidity of the air, the direction and velocity of the wind and the electric field strength of the conductor. The equations are the basis of a proposed thermodynamic method of monitoring the intensity of ice formation. Versions of a technical method and algorithms of the functioning of ice-formation monitoring are proposed.

42 ENGINEERING↗
NASA NTRS1971

Optimization of conical hydrostatic bearing for minimum friction.

Equations for the flow rate, load capacity, and friction torque for a conical hydrostatic bearing were developed. These equations were solved by a digital computer program to determine bearing configurations for minimum friction torque. Design curves are presented that show optimal bearing dimensions for minimum friction torque as a function of dimensionless flow rate for a range of dimensionless load capacity. Results are shown for both laminar and turbulent flow conditions. The results indicate that hydrostatic pocket friction is a significant portion of the total friction torque. However, the bearing dimensions for a minimum friction design are affected very little by inclusion of pocket friction in the analysis. For laminar flow the values of the outer-land radius ratio X3 and outer bearing radius ratio X4 did not change significantly with increasing friction factor. For turbulent flow, the outer bearing radius ratio X4 did not change with increasing friction factor; therefore the value determined for X4 in the laminar flow case is valid for all turbulent flows.

Nypan, L. J.↗
NASA NTRS1972

Flow field measurements for space-shuttle-related cylindrical configurations in hypersonic streams.

Use of surface pressures, heat-transfer rates, and flow-visualization photographs to define the flowfields for simulated infinite cylinders. Four cylindrical cross sections were studied in the experimental program, which was conducted at free-stream Mach numbers of 5 to 15, free-stream unit Reynolds numbers from 2 to 20 million per foot, and angles of attack from 30 to 90 deg. Although swept-cylinder theory provides a reasonable correlation of the measured laminar heat-transfer rates in the plane of symmetry, improved correlation with the measurements is obtained if the three-dimensional nature of the flow is taken into account. In cases where the boundary layer on the windward forebody was turbulent, the large velocity gradients near the chines produced relaminarization of the boundary layer prior to separation. The average heat-transfer-rate in the separated region, which is weakly dependent on the free-stream conditions, was found to be a linear function of the angle of attack. For a given flow condition the effect of the leeward geometry on heat transfer can be correlated by a single geometric parameter which is dependent on the location of separation.

Bertin, J. J.↗
NASA NTRS1974

Burning rate response of liquid monopropellants to imposed pressure oscillations

The combustion characteristics of hydrazine strands were studied under both steady state and oscillatory conditions. A steady strand burner was used to measure steady strand burning rates, liquid temperature distributions and surface temperatures as a function of pressure in the pressure range of 0.32 to 42 atm. It was found that for subatmospheric pressures the burning rate varied as the square root of pressure; for pressures greater than atmospheric the burning rate varied linearly with pressure. A theoretical model of the strand combustion system was developed and matched to the steady burning rates by assuming a reaction order of one for subatmospheric pressures and a reaction order of two for pressures greater than atmospheric. The model was also found to be in good agreement with measurements of liquid temperature distributions and surface temperatures. The results show an increse in the response of the combustion process as interaction occurs with transient liquid phase effects, yielding a band of frequencies where the combustion process exerts sufficient amplifying power to provide a mechanism for driving combustion instability.

Allison, C. B.↗
NASA NTRS1979

The energetics of resistive magnetic tearing

A new treatment of the energetics of resistive magnetic tearing is presented. This instability is the only known field-reconnection mechanism which develops in time, and is thus a primary candidate for a number of astrophysical 'flare' processes occurring in stressed magnetic fields. The tearing process is elucidated by a subdivision into magnetic regions of different characteristics: first, as dominated by resistive or highly conductive dynamics, and then by function as a source or sink of the energy flux. Matching conditions between these zones provide a determination of the growth rate and its physical-parameter dependence. The observable plasma energy outputs, due mainly to two distinct magnetically driven acceleration mechanisms, are estimated and their directive spatial properties shown. Finally, the generality of resistive tearing is demonstrated by an application of the previous considerations to realistic sheared-field configurations, including the case of a solar coronal loop, for which flare-instability thresholds and energy-deposition sites are described.

Van Hoven, G.↗
NASA NTRS1990

An analysis of the threshold method for measuring area-average rainfall

Experimental evidence shows that the area-average rain rate and the fractional area covered by rain rate exceeding a fixed threshold are highly correlated; that is, are highly linearly related. A precise theoretical explanation of this fact is given. The explanation is based on the observation that rain rate has a mixed distribution, one that is a mixture of a discrete distribution and a continuous distribution. Under a homogeneity assumption, the slope of the linear relationship depends only on the continuous part of the distribution and as such is found to be markedly immune to parameter changes. This is illustrated by certain slope surfaces obtained from three specific distributions. The threshold level can be chosen in an optimal way by minimizing a certain distance function defined over the threshold range. In general, the threshold level should be not too far from the mean rain rate conditional on rain. The so-called threshold method advocates measuring rainfall from fractional area exploiting the observed linear relationship of the later with the area average rain rate. The method is potentially useful for the estimation of rainfall from space via satellites.

Kedem, Benjamin↗
NASA NTRS1993

Quasi-optical grids with thin rectangular patch/aperture elements

Theoretical analysis is presented for an efficient and accurate performance evaluation of quasi-optical grids comprised of thin rectangular patch/aperture elements with/without a dielectric substrate/superstrate. The convergence rate of this efficient technique is improved by an order of magnitude with the approximate edge conditions incorporated in the basis functions of the integral equation solution. Also presented are the interesting applications of this efficient analytical technique to the design and performance evaluation of the coupling grids and beam splitters in the optical systems as well as thermal protection sunshields used in the communication systems of satellites and spacecrafts.

Wu, Te-Kao↗
NASA NTRS2003

Investigation of Dynamic Oxygen Adsorption in Molten Solder Jetting Technology

Surface tension forces play a critical role in fluid dynamic phenomena that are important in materials processing. The surface tension of liquid metals has been shown to be very susceptible to small amounts of adsorbed oxygen. Consequently, the kinetics of oxygen adsorption can influence the capillary breakup of liquid-metal jets targeted for use in electronics assembly applications, where low-melting-point metals (such as tin-containing solders) are utilized as an attachment material for mounting of electronic components to substrates. By interpreting values of surface tension measured at various surface ages, adsorption and diffusion rates of oxygen on the surface of the melt can be estimated. This research program investigates the adsorption kinetics of oxygen on the surface of an atomizing molten-metal jet. A novel oscillating capillary jet method has been developed for the measurement of dynamic surface tension of liquids, and in particular, metal melts which are susceptible to rapid surface degradation caused by oxygen adsorption. The experimental technique captures the evolution of jet swells and necks continuously along the jet propagation axis and is used in conjunction with an existing linear, axisymmetric, constant-property model to determine the variation of the instability growth rate, and, in turn, surface tension of the liquid as a function of surface age measured from the exit orifice. The conditions investigated so far focus on a time window of 2-4ms from the jet orifice. The surface properties of the eutectic 63%Sn-37%Pb solder alloy have been investigated in terms of their variation due to O2 adsorption from a N2 atmosphere containing controlled amounts of oxygen (from 8 ppm to 1000 ppm). The method performed well for situations where the oxygen adsorption was low in that time window. The value of surface tension for the 63Sn-37Pb solder in pure nitrogen was found to be 0.49 N/m, in good agreement with previously published work. A characteristic time of O(1ms) or less was determined for the molten-metal surface to be saturated by oxygen at 1000 ppm concentration in N2.

Megaridis, Constantine M.↗
NASA NTRS2014

Design, Integration, Certification and Testing of the Orion Crew Module Propulsion System

The Orion Multipurpose Crew Vehicle (MPCV) is NASA's next generation spacecraft for human exploration of deep space. Lockheed Martin is the prime contractor for the design, development, qualification and integration of the vehicle. A key component of the Orion Crew Module (CM) is the Propulsion Reaction Control System, a high‐flow hydrazine system used during re‐entry to orient the vehicle for landing. The system consists of a completely redundant helium (GHe) pressurization system and hydrazine fuel system with monopropellant thrusters. The propulsion system has been designed, integrated, and qualification tested in support of the Orion program's first orbital flight test, Exploration Flight Test One (EFT‐1), scheduled for 2014. A subset of the development challenges and lessons learned from this first flight test campaign will be discussed in this paper for consideration when designing future spacecraft propulsion systems. The CONOPS and human rating requirements of the CM propulsion system are unique when compared with a typical satellite propulsion reaction control system. The system requires a high maximum fuel flow rate. It must operate at both vacuum and sea level atmospheric pressure conditions. In order to meet Orion's human rating requirements, multiple parts of the system must be redundant, and capable of functioning after spacecraft system fault events.

McKay, Heather↗
NASA NTRS2018

Ultralow Frequency Waves as an Intermediary for Solar Wind Energy Input Into the Radiation Belts

Enhancements of electron fluxes in the outer radiation belt have been closely linked to increases in solar wind speed and density as well as to prolonged intervals of southward interplanetary magnetic field. Periodic oscillations in the Earth's magnetic field with frequencies in the range of a few millihertz (ultralow frequency or ultralow frequency waves) may be an intermediary through which these solar wind drivers influence radiation belt dynamics due to their potential for resonant interactions with energetic electrons causing the radial migration of resonant electrons. Using data from more than 180 ground magnetometers contributing to the worldwide SuperMAG collaboration, we explore possible relationships between relativistic electron flux variations and the spatial and temporal profiles of ultralow frequency wave power contained in the Pc5 frequency band (2–7 mHz). During 19 geomagnetic storms marked by relativistic (1.5 MeV < E < 6 MeV) electron flux enhancements and 19 storms that led to prolonged electron flux depletions, Pc5 wave power is found penetrating to L shells as low as 2–3. The enhancement of Pc5 wave power starts almost simultaneously with the storm onset. The depth of wave activity penetration was found associated with the strength of geomagnetic activity (Spearman's ρ = 0.54), which is also related to the location of electron flux maximum observed in the recovery phase. Pc5 wave activity persists longer (for up to ≈62 hr) for those storms that produced relativistic electrons. We also investigate the combination of interplanetary conditions necessary to differentiate the response of relativistic electron fluxes to geomagnetic storms. A coupling function that captures the increased reconnection rate at the dayside magnetopause affecting magnetospheric processes which may produce Pc5 wave power offers an additional key to further understanding the outer belt dynamics.

Georgiou, M.↗
NASA NTRSDate not supplied

Ice Growth Model and Lunar Tanker for Polar Water Extraction

In-Situ Resource Utilization (ISRU) is a major component of sustainable and cost-effective missions to the Moon and beyond. Ever since it has been identified in the Permanently Shadowed Regions (PSRs) of the Moon, water has become a resource of interest for it’s wide range of uses such as life support and hydrogen and oxygen rocket propellant. It is ice-bound in the regolith, so separation typically involves heating to sublimation temperatures and capturing at very low pressure. One option is to then store it in ice form and transport it out of the PSR and into a sunlit ridge. From here, processes such as electrolysis can be performed. An understanding of frost growth dynamics under rarefied conditions is necessary for successful water production, though. An analytical model was developed using a Diffusion-Limited Aggregation (DLA) approach to evaluate bulk thermal conductivity changes of frost under varying conditions. This model will be evaluated using a one-dimensional frost growth experiment on a horizontal, flat plate under vacuum and cryogenic conditions. The tests will measure frost growth rate and bulk density, and the thermal conductivity of the ice layer as a function of thickness for different plate temperatures. The test data will then be used to validate and improve the analytical model.

Lunar water↗
NASA NTRSDate not supplied

Simulation Studies for an Urban Air Mobility Aircraft using Hardware-In-Loop Experiments

Urban Air Mobility seeks to transport passengers, deliver cargo, and provide emergency medical transportation in major metropolitan areas. This will be accomplished with distributed electric powered vertical takeoff and landing aircraft vehicles. The low specific energy of the current generation lithium-ion battery packs limit the operational range of the electric aircraft. Limited range impacts safety by reducing the amount of time available for analyzing the potential impact of errors and failures and responding to them, and for flying to an alternative landing area or returning to the base. It is therefore critical to understand the impact of flight and environmental conditions on the onboard lithium-ion battery pack’s health. With this as the motivation, the procedure for evaluating the performance of battery packs in a laboratory setting and the results obtained using this procedure on battery packs subject to power draw characteristics of a simulated flight of a NASA conceptual quadrotor aircraft model are described. The fully charged battery is allowed to discharge at specific C-rates based on the power draw profile during the experiment, and the current and voltages are recorded as a function of time. Observed results under different operating conditions and mission profiles are discussed.

UAM↗
NASA NTRS1999

Fracture Mechanics of Thin, Cracked Plates Under Tension, Bending and Out-of-Plane Shear Loading

Cracks in the skin of aircraft fuselages or other shell structures can be subjected to very complex stress states, resulting in mixed-mode fracture conditions. For example, a crack running along a stringer in a pressurized fuselage will be subject to the usual in-plane tension stresses (Mode-I) along with out-of-plane tearing stresses (Mode-III like). Crack growth and initiation in this case is correlated not only with the tensile or Mode-I stress intensity factor, K(sub I), but depends on a combination of parameters and on the history of crack growth. The stresses at the tip of a crack in a plate or shell are typically described in terms of either the small deflection Kirchhoff plate theory. However, real applications involve large deflections. We show, using the von-Karman theory, that the crack tip stress field derived on the basis of the small deflection theory is still valid for large deflections. We then give examples demonstrating the exact calculation of energy release rates and stress intensity factors for cracked plates loaded to large deflections. The crack tip fields calculated using the plate theories are an approximation to the actual three dimensional fields. Using three dimensional finite element analyses we have explored the relationship between the three dimensional elasticity theory and two dimensional plate theory results. The results show that for out-of-plane shear loading the three dimensional and Kirchhoff theory results coincide at distance greater than h/2 from the crack tip, where h/2 is the plate thickness. Inside this region, the distribution of stresses through the thickness can be very different from the plate theory predictions. We have also explored how the energy release rate varies as a function of crack length to plate thickness using the different theories. This is important in the implementation of fracture prediction methods using finite element analysis. Our experiments show that under certain conditions, during fatigue crack growth, the presence of out-of-plane shear loads induces a great deal of contact and friction on the crack surfaces, dramatically reducing crack growth rate. A series of experiments and a proposed computational approach for accounting for the friction is discussed.

Zehnder, Alan T.↗
DOE OSTI2019

Investigation of Thermolytic Production of Hydrogen Applicable to Savannah River Site High Level Waste - 19443

Several experiments have been performed to measure the generation rates of hydrogen gas due to reaction (thermolysis) of organic compounds in both simulated and radioactive waste. Initial measurements of hydrogen generation rates at 100 deg. C were made to downselect molecules and functional groups that produce significant amounts of hydrogen for subsequent kinetic determination. A statistically-designed test matrix was employed to quantitatively determine chemical conditions of highest reactivity at 100 deg. C. Additional experiments were performed at 100 deg. C to determine the impact of specific chemical components on hydrogen generation rates for relevant organic compounds. A semi-empirical model for thermolytic hydrogen generation rate from glycolate at 100 deg. C was developed and compared to results from radioactive waste and literature reports. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
DOE OSTI2016

Electron energy distribution functions and fractional power transfer in “cold” and excited CO{sub 2} discharge and post discharge conditions

A Boltzmann equation, in the presence of superelastic vibrational and electronic collisions and of electron-electron Coulomb collisions, has been solved in CO{sub 2} plasma in discharge and post discharge conditions. Superelastic vibrational collisions play an important role in affecting the electron energy distribution function (eedf) in a wide range of the reduced electric field E/N and of vibrational temperatures characterizing the vibrational modes of CO{sub 2}. An important result is the dependence of fractional power losses and of the relevant rate coefficients on the vibrational temperatures of the system. Superelastic electronic collisions, on the other hand, are the main processes affecting eedf and related quantities in the post discharge conditions (i.e., E/N = 0). In particular at low vibrational temperatures, the superelastic electronic collisions form an important plateau in the eedf, largely influencing the rate coefficients and the fractional power transfer.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
NASA NTRS1980

Head-up transition behavior of pilots during simulated low-visibility approaches

Each of 13 commercial pilots from four airlines flew a total of 108 manual flight director approaches in a moving base simulation of a medium-sized turbojet (95,000 lb gross weight) which had a day and night Redifon external scene. Three levels of runway visual range (RVR) (1,600; 2,400; and greater than 8,000 ft), three wind-shear profiles, nine ceiling heights, and continuous and intermittent visibility after initial breakout were tested. The results indicated that: (1) mean decision time ranged from 2 to 4.6 sec for ceilings under 380 ft across the three RVR conditions; (2) mean vertical distance traveled during the visual-cue assessment period was a relatively constant proportion below the existing ceiling; (3) a significant three way interaction in mean decision time between wind shear, day-night, and ceiling RVR variables occurred; (4) mean number of head-up transitions to VFR conditions after breakout ranged from 4.6 to 13.4 and increased as a function of ceiling and severity of wind shear; the typical duration of fixation out the window was 1.5 sec; and (5) subjective pilot ratings of controllability and precision of control as well as amount of skill, attention, or effort required to make the landing were influenced significantly by the wind shear, night conditions, and low breakout ceiling conditions.

Haines, R. F.↗