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At least 253 records · Page 14

Test results of a diffraction grating beam combiner

A laser diode beam combiner employing diffraction gratings has been fabricated and tested. The Grating Laser Beam Combiner (GLBC) uses two holographic diffraction gratings to incoherently combine the first order diffraction components of four 35 mW AlGaAs lasers. The grating rhomb design minimizes the transmitter sensitivity to the inherent frequency instability of laser diodes. The overall throughput of the combiner is 74 percent. Each laser was temperature controlled to 0.1 C and modulated with 110 Mbps QPPM data. Two lasers under modulation were coaligned to within 76 microrad with a combined average power of 45 mW.

Rall, Jonathan A.↗

Expanding the Natural Laminar Flow Boundary for Supersonic Transports

A computational design and analysis methodology is being developed to design a vehicle that can support significant regions of natural laminar flow (NLF) at supersonic flight conditions. The methodology is built in the CDISC design module to be used in this paper with the flow solvers Cart3D and USM3D, and the transition prediction modules BLSTA3D and LASTRAC. The NLF design technique prescribes a target pressure distribution for an existing geometry based on relationships between modal instability wave growth and pressure gradients. The modal instability wave growths (both on- and off-axes crossflow and Tollmien-Schlichting) are balanced to produce a pressure distribution that will have a theoretical maximum NLF region for a given streamwise wing station. An example application is presented showing the methodology on a generic supersonic transport wingbody configuration. The configuration has been successfully redesigned to support significant regions of NLF (approximately 40% of the wing upper surface by surface area). Computational analysis predicts NLF with transition Reynolds numbers (ReT) as high as 36 million with 72 degrees of leading-edge sweep (ΛLE), significantly expanding the current boundary of ReT - ΛLE combinations for NLF. This NLF geometry provides a total drag savings of 4.3 counts compared to the baseline wing-body configuration (approximately 5% of total drag). Off-design evaluations at near-cruise and low-speed, high-lift conditions are discussed, as well as attachment line contamination/transition concerns. This computational NLF design effort is a part of an ongoing cooperative agreement between NASA and JAXA researchers.

Lynde, Michelle N.↗

Models of Jovian decametric radiation

We present a critical review of theoretical models of Jovian decametric radiation, with particular emphasis on the Io-modulated emission. The problem is divided into three broad aspects: the mechanism coupling Io's orbital motion to the inner exosphere, the consequent instability mechanism by which electromagnetic waves are amplified, and the subsequent propagation of the waves in the source region and the Jovian plasmasphere. At present there exists no comprehensive theory that treats all of these aspects quantitatively within a single framework. Acceleration of particles by plasma sheaths near Io appears to be a promising explanation for the coupling mechanism, while most of the properties of the emission may be explained in the context of cyclotron instability of a highly anisotropic distribution of streaming particles. The present state of the theory is evaluated, and some suggested approaches for future work are discussed.

Smith, R. A.↗

A bromodomain-independent mechanism of gene regulation by the BET inhibitor JQ1: direct activation of nuclear receptor PXR

Abstract Bromodomain and extraterminal (BET) proteins are extensively studied in multiple pathologies, including cancer. BET proteins modulate transcription of various genes, including those synonymous with cancer, such as MYC. Thus, BET inhibitors are a major area of drug development efforts. (+)-JQ1 (JQ1) is the prototype inhibitor and is a common tool to probe BET functions. While showing therapeutic promise, JQ1 is not clinically usable, partly due to metabolic instability. Here, we show that JQ1 and the BET-inactive (−)-JQ1 are agonists of pregnane X receptor (PXR), a nuclear receptor that transcriptionally regulates genes encoding drug-metabolizing enzymes such as CYP3A4, which was previously shown to oxidize JQ1. A PXR-JQ1 co-crystal structure identified JQ1′s tert-butyl moiety as a PXR anchor and explains binding by (−)-JQ1. Analogs differing at the tert-butyl lost PXR binding, validating our structural findings. Evaluation in liver cell models revealed both PXR-dependent and PXR-independent modulation of CYP3A4 expression by BET inhibitors. We have characterized a non-BET JQ1 target, a mechanism of physiological JQ1 instability, a biological function of (−)-JQ1, and BET-dependent transcriptional regulation of drug metabolism genes.

59 BASIC BIOLOGICAL SCIENCES↗

Channeling acceleration in crystals and nanostructures and studies of solid plasmas: new opportunities

In this study, plasma wakefield acceleration (PWFA) has shown illustrious progress and resulted in an impressive demonstration of tens of GeV particle acceleration in meter-long single structures. To reach even higher energies in the 1 TeV to 10 TeV range, a promising scheme is channeling acceleration in solid-density plasmas within crystals or nanostructures. The E336 experiment studies the beam-nanotarget interaction with the highly compressed electron bunches available at the FACET-II accelerator. These studies furthermore involve an in-depth research on dynamics of beam-plasma instabilities in ultra-dense plasma, its development and suppression in structured media like carbon nanotubes and crystals, and its potential use to transversely modulate the electron bunch.

43 PARTICLE ACCELERATORS↗

Characteristics of a Lunar Landing Configuration Having Various Multiple-Leg Landing-Gear Arrangements

An experimental investigation has been made of some lunar-landing characteristics of a 1/6-scale dynamic model of a landing module having multiple-leg landing-gear systems. Symmetric four-point and five-point systems were investigated. The landing-gear legs were inverted tripod arrangements having a telescoping main strut which incorporated a yielding-metal strap for energy dissipation, hinged V-struts, and circular pads. The landing tests were made by launching a free model onto an impenetrable hard surface (concrete) and onto a powdered-pumice overlay of various depths. Landing motion and acceleration data were obtained for a range of touchdown speeds, touchdown attitudes, and landing-surface conditions. Maximum normal acceleration experienced at the module center of gravity during landings on hard surface or pumice was 2g (full-scale lunar value in terms of earth's gravity) over a wide range of touchdown conditions. acceleration experienced was 12 1/2 radians/sec(exp 2) and maximum longitudinal acceleration was 1 3/4g. The module was very stable with all gear configurations during landings on hard surface (coefficient of friction, micron = 0.4) at all conditions tested. Some overturn instability occurred during landings on powdered pumice (micron = 0.7 to 1.0) depending upon flight path, pitch and yaw attitude, depth of pumice, surface topography, and landing-gear configuration. The effect on stability of roll attitude for the limited amount of roll-attitude landing data obtained was insignificant. Compared with the four-point landing gear, the five-point system with equal maximum gear radius increased landing stability slightly and improved the static stability for subsequent lunar launch. A considerable increase in landing stability in the direction of motion was obtained with an asymmetric four-point gear having two pads offset to increase gear radius by 33 percent in the direction of horizontal flight.

Blanchard, Ulysse J.↗

New aspects of whistler waves driven by an electron beam studied by a 3-D electromagnetic code

We have restudied electron beam driven whistler waves with a 3-D electromagnetic particle code. The simulation results show electromagnetic whistler wave emissions and electrostatic beam modes like those observed in the Spacelab 2 electron beam experiment. It has been suggested in the past that the spatial bunching of beam electrons associated with the beam mode may directly generate whistler waves. However, the simulation results indicate several inconsistencies with this picture: (1) whistler waves continue to be generated even after the beam mode space charge modulation looses its coherence, (2) the parallel (to the background magnetic field) wavelength of the whistler wave is longer than that of the beam instability, and (3) the parallel phase velocity of the whistler wave is smaller than that of the beam mode. The complex structure of the whistler waves in the vicinity of the beam suggest that the transverse motion (gyration) of the beam and background electrons is also involved in the generation of whistler waves.

Nishikawa, Ken-Ichi↗

The Role of Gravity Waves in Modulating Atmospheric Tides

We discuss results for the diurnal and semidiurnal tides obtained from our 3-D, time dependent numerical spectral model (NMS), extending from the ground up into the thermosphere, which incorporates Hines' Doppler spread parameterization of small scale gravity waves (GW). In the DSP, GW momentum (and energy) are conserved as the waves modulate the background flow and are filtered by the flow.As a consequence, the GW interaction tightly couples the dynamic components of the middle atmosphere with strong non-linear interactions between mean zonal circulation, tides and planetary waves to produce complicated patterns of variability much like those observed. The major conclusions are: (1) Since GW momentum is deposited in the altitude regime of increasing winds, the amplitude of the diurnal tide is amplified and its vertical wavelength is reduced at altitudes between 80 and 120 km. Wave filtering by the mean zonal circulation (with peak velocities during solstice) causes the GW flux to peak during equinox, and this produces a large semi-annual variation in the tide that has been observed on UARS. (2) Without the diurnal tide, the semidiurnal tide would also be modulated in this way. But the diurnal tide filters out the GW preferentially during equinox, so that the semidiurnal tide, at higher altitudes, tends to peak during solstice. (3) Under the influence of GW, the tides are modulated also significantly by planetary waves, with periods between 2 and 30 days, which are generated preferentially during solstice in part due to baroclinic instability.

Mayr, H. G.↗

Characteristics of a Lunar Landing Configuration Having Various Multiple-Leg Landing-Gear Arrangements

An experimental investigation has been made of some lunar-landing characteristics of a 1/6-scale dynamic model of a landing module having multiple-leg landing-gear systems. Symmetric four-point and five-point systems and an asymmetric four-point system were investigated. The landing-gear legs were inverted tripod arrangements having a telescoping main strut which incorporated a yielding-metal strap for energy dissipation, hinged V-struts, and circular pads. The landing tests were made by launching a free model onto an impenetrable hard surface (concrete) and onto a powdered-pumice overlay of various depths. Landing motion and acceleration data were obtained for a range of touchdown speeds, touchdown speeds, touch attitudes, and landing-surface conditions. Symmetric four-point and five-point systems and an Maximum normal acceleration experienced at the module center of gravity during landings on hard surface or pumice was 2g (full-scale lunar value in terms of earth's gravity) over a wide range of touchdown conditions. Maximum angular acceleration experienced was 12-1/2 radians/sec(exp 2) and maximum longitudinal acceleration was 1-3/4 g. The module was very stable with all gear configurations during landings on hard surface (coefficient of friction, microns=0.4) at all conditions tested. Some overturn instability occurred during landings on powdered pumice (microns=0.7 to 1.0) depending upon flight path, pitch and yaw attitude, depth of pumice, surface topography, and landing-gear configuration. The effect of stability of roll attitude for the limited amount of roll-attitude landing data obtained was insignificant. Compared with the four-point system, the five-point system with equal maximum gear radius increased landing stability slightly and improved the static stability for subsequent lunar launch. A considerable increase in landing stability in the direction of motion was obtained with an asymmetric four-point gear having two pads offset to increase gear radius by 33 percent in the direction of horizontal flight.

Blanchard, Ulysse J.↗

Measurement of Kinetic-Scale Current Filamentation Dynamics and Associated Magnetic Fields in Interpenetrating Plasmas

Here, we present the first local, quantitative measurements of ion current filamentation and magnetic field amplification in interpenetrating plasmas, characterizing the dynamics of the ion Weibel instability. The interaction of a pair of laser-generated, counterpropagating, collisionless, supersonic plasma flows is probed using optical Thomson scattering (TS). Analysis of the TS ion-feature revealed anticorrelated modulations in the density of the two ion streams at the spatial scale of the ion skin depth c/ω pi = 120 μm, and a correlated modulation in the plasma current. The inferred current profile implies a magnetic field amplitude ~30 ± 6 T , corresponding to ~1% of the flow kinetic energy, indicating that magnetic trapping is the dominant saturation mechanism.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Asymptotic behavior of modulated Taylor-Couette flows with a crystalline inner cylinder

The linear stability of a modulated Taylor-Couette system when the inner cylindrical boundary consists of a crystalline solid-liquid interface is considered. Both experimentally and in numerical calculations it is found that the two-phase system is significantly less stable than the analogous rigid-walled system for materials with moderately large Prandtl numbers. A numerical treatment based on Floquet theory is described, which gives results that are in good agreement with preliminary experimental findings. In addition, this instability is further examined by carrying out a formal asymptotic expansion of the solution in the limit of large Prandtl number. In this limit the Floquet analysis is considerably simplified, and the linear stability of the modulated system can be determined to leading order through a conventional stability analysis, without recourse to Floquet theory. The resulting simplified problem is then studied for both the narrow gap geometry and for the case of a finite gap. It is surprising that the determination of the linear stability of the two-phase system is considerably simpler than that of the rigid-walled system, despite the complications introduced by the presence of the crystal-melt interface.

Braun, R. J.↗

Models of Jovian decametric radiation

A critical review is presented of theoretical models of Jovian decametric radiation, with particular emphasis on the Io-modulated emission. The problem is divided into three broad aspects: (1) the mechanism coupling Io's orbital motion to the inner exosphere, (2) the consequent instability mechanism by which electromagnetic waves are amplified, and (3) the subsequent propagation of the waves in the source region and the Jovian plasmasphere. At present there exists no comprehensive theory that treats all of these aspects quantitatively within a single framework. Acceleration of particles by plasma sheaths near Io is proposed as an explanation for the coupling mechanism, while most of the properties of the emission may be explained in the context of cyclotron instability of a highly anisotropic distribution of streaming particles.

Smith, R. A.↗

Nonlinear evolution of astrophysical Alfven waves

Nonlinear Alfven waves were studied using the derivative nonlinear Schrodinger equation as a model. The evolution of initial conditions, such as envelope solitons, amplitude-modulated waves, and band-limited noise was investigated. The last two furnish models for naturally occurring Alfven waves in an astrophysical plasma. A collapse instability in which a wave packet becomes more intense and of smaller spatial extent was analyzed. It is argued that this instability leads to enhanced plasma heating. In studies in which the waves are amplified by an electron beam, the instability tends to modestly inhibit wave growth.

Spangler, S. R.↗

An analysis of the shocklike electrostatic noise observed during AMPTE solar wind ion releases

Electrostatic waves produced by the interaction of the ion cloud with the solar wind are analyzed in order to explain the shocklike noise detected by the Ion Release Module instruments during the Active Magnetospheric Particle Tracer Explorers solar wind ion releases. The results indicate that the shocklike noise can be generated by two instabilities, an ion-electron instability that occurs for waves propagating parallel to the solar wind velocity and an ion-ion instability that occurs for waves propagating at a large angle to the solar wind direction. Both instabilities give high growth rates for both the lithium and barium releases. The calculated results agree with the observed ones in all main features. In the earlier stage of the ion cloud expansion, both instabilities are likely to occur, while in the later stage the ion-ion instability is more likely to occur.

Ma, T. Z.↗

Time-dependent X-ray emission from unstable accretion disks around black holes

The spectral evolution of accretion disks in X-ray binaries containing black holes is studied, based on the disk instability model. The thermal transition of the outer portions of the disk controls the mass flow rate into the inner portions of the disk, thus modulating the soft X-ray flux which is thought to arise from the inner disk. Calculated soft X-ray spectra are consistent with the observations of the X-ray transient A0620 - 00 and especially ASM 2000 + 25, the soft X-ray spectra of which are well fitted by blackbody radiation with a fixed inner edge of the disk, Rin, and with monotonically decreasing temperature at Rin with time. Since the gas pressure is always dominant over the radiation pressure during the decay in these models, a two-temperature region is difficult to create. Instead, it is suggested that hard X-rays are generated in a hot (kT greater than 10 keV) accretion disk corona above the cool (kT less than 1 keV) disk.

Mineshige, Shin↗

Early Oscillation Detection for DC/DC Converter Fault Diagnosis

The electrical power system of a spacecraft plays a very critical role for space mission success. Such a modern power system may contain numerous hybrid DC/DC converters both inside the power system electronics (PSE) units and onboard most of the flight electronics modules. One of the faulty conditions for DC/DC converter that poses serious threats to mission safety is the random occurrence of oscillation related to inherent instability characteristics of the DC/DC converters and design deficiency of the power systems. To ensure the highest reliability of the power system, oscillations in any form shall be promptly detected during part level testing, system integration tests, flight health monitoring, and on-board fault diagnosis. The popular gain/phase margin analysis method is capable of predicting stability levels of DC/DC converters, but it is limited only to verification of designs and to part-level testing on some of the models. This method has to inject noise signals into the control loop circuitry as required, thus, interrupts the DC/DC converter's normal operation and increases risks of degrading and damaging the flight unit. A novel technique to detect oscillations at early stage for flight hybrid DC/DC converters was developed.

Wang, Bright L.↗

Acoustically-induced modulation spectroscopy for ultra-sensitive gas analysis

A new optical technique has been developed for ultra-sensitive attenuation measurements in gaseous media and, in particular, for determination of low levels of smoke emitted from jet engines. It is a variation on direct light transmission where the sample gas density in a cell is modulated acoustically by a speaker. The amplitude variation of the light transmission is proportional to the gas density and is insensitive to window contamination and detector instabilities. Preliminary analysis and experiments indicate that the instrument promises to measure light absorption to less than 1 percent per meter and allow measurment of smoke emissions from 1 to 100 mg/cu m. The technique has been demonstrated through the use of an absorbing gas, viz., 200 ppm of NO2 in N2 which produces 25 percent per meter absorption.

Pitz, R. W.↗

Development of a Practical Methodology for Elastic-Plastic and Fully Plastic Fatigue Crack Growth

A practical engineering methodology has been developed to analyze and predict fatigue crack growth rates under elastic-plastic and fully plastic conditions. The methodology employs the closure-corrected effective range of the J-integral, delta J(sub eff) as the governing parameter. The methodology contains original and literature J and delta J solutions for specific geometries, along with general methods for estimating J for other geometries and other loading conditions, including combined mechanical loading and combined primary and secondary loading. The methodology also contains specific practical algorithms that translate a J solution into a prediction of fatigue crack growth rate or life, including methods for determining crack opening levels, crack instability conditions, and material properties. A critical core subset of the J solutions and the practical algorithms has been implemented into independent elastic-plastic NASGRO modules. All components of the entire methodology, including the NASGRO modules, have been verified through analysis and experiment, and limits of applicability have been identified.

McClung, R. C.↗