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At least 253 records · Page 14

Beam delivery and final focus systems for multi-TeV advanced linear colliders

The Beam Delivery System (BDS) is a critical component of a high-energy linear collider. It transports the beam from the accelerator and brings it to a focus at the Interaction Point. The BDS system includes diagnostic sections for measuring the beam energy, emittance, and polarization, as well as collimators for machine protection. The length of the BDS increases with collision energy. Higher collision energies also require higher luminosities, and this is a significant constraint on the design for energy-frontier machines. Here, we review BDS designs based on traditional quadrupole magnets and examine the challenges involved in extending these to the Multi-TeV regime consistent with requirements for advanced accelerator concepts.

43 PARTICLE ACCELERATORS↗

Beam delivery and beamstrahlung considerations for ultra-high energy linear colliders

As part of the Snowmass'21 community planning excercise, the Advanced Accelerator Concepts (AAC) community proposed future linear colliders with center-of-mass energies up to 15 TeV and luminosities up to 50 × 1034 cm -2 s -1 in a compact footprint. In addition to being compact, these machines must also be energy efficient. We identify two challenges that must be addressed in the design of these machines. First, the Beam Delivery System (BDS) must not add significant length to the accelerator complex. Second, beam parameters must be chosen to mitigate beamstrahlung effects and maximize the luminosity-per-power of the machine. In this paper, we review advances in plasma lens technology that will help to reduce the length of the BDS system, and we detail new Particle-in-Cell simulation studies that will provide insight into beamstrahlung mitigation techniques. We apply our analysis to both $e$ + $e$ - and $γγ$ colliders. The challenges and solutions described in this paper are considered independently. In conclusion, a unified, self-consistent concept for a BDS system for a 15 TeV linear collider will be the subject of future work.

47 OTHER INSTRUMENTATION↗

High voltage delivery and distribution for the NEXT-100 Time Projection Chamber

A critical element in the realization of large liquid andgas time projection chambers (TPCs) is the delivery and distributionof high voltages into and around the detector. Such experimentsrequire of order tens of kilovolts to enable electron drift overmeter-scale distances. This paper describes the design andoperation of the cathode feedthrough and high voltage distributionthrough the field cage of the NEXT-100 experiment, an undergroundTPC that will search for neutrinoless double beta decay0νββ. The feedthrough has been demonstrated to holdpressures up to 20 bar and sustain voltages as high as -65 kV.The TPC is operating stably at its design high voltages. The systemhas been realized within the constraints of a stringent radiopuritybudget and is now being used to execute a suite of sensitive doublebeta decay analyses.

Adams, C. [Argonne]↗

Heritable, multinucleotide deletions in plants using viral delivery of a repair exonuclease and guide RNAs

Abstract CRISPR/Cas9-mediated mutagenesis typically results in short insertion/deletion mutations, which are often too small to disrupt the function of cis-acting regulatory elements. Here, we describe a highly efficient in planta gene editing approach called VirTREX2-HLDel that achieves heritable multinucleotide deletions in both protein-coding genes and noncoding DNA regulatory elements. VirTREX2-HLDel uses RNA viruses to deliver both the 3 prime repair exonuclease 2 (TREX2) and single-guide RNAs. Our method enables recovery of multiplexed heritable deletions and increases the heritable gene editing frequency at poorly edited sites. We identified functional conservation and divergence of MICRORNA164 (miR164) in Nicotiana benthamiana and tomato (Solanum lycopersicum) using VirTREX2-HLDel and observed previously uncharacterized phenotypes in plants with large deletions at this locus. Our viral delivery method reduces the need for tissue culture and will accelerate the understanding of protein-coding and regulatory regions in plants.

59 BASIC BIOLOGICAL SCIENCES↗

Efficient delivery of a DNA aptamer-based biosensor into plant cells for glucose sensing through thiol-mediated uptake

DNA aptamers have been widely used as biosensors for detecting a variety of targets. Despite decades of success, they have not been applied to monitor any targets in plants, even though plants are a major platform for providing oxygen, food, and sustainable products ranging from energy fuels to chemicals, and high-value products such as pharmaceuticals. A major barrier to progress is a lack of efficient methods to deliver DNA into plant cells. We herein report a thiol-mediated uptake method that more efficiently delivers DNA into Arabidopsis and tobacco leaf cells than another state-of-the-art method, DNA nanostructures. Such a method allowed efficient delivery of a glucose DNA aptamer sensor into Arabidopsis for sensing glucose. This demonstration opens a new avenue to apply DNA aptamer sensors for functional studies of various targets, including metabolites, plant hormones, metal ions, and proteins in plants for a better understanding of the biodistribution and regulation of these species and their functions.

59 BASIC BIOLOGICAL SCIENCES↗

Mitigation of External Exposure of Energy Delivery System (MEEDS).

MEEDS is a cybersecurity solution that empowers under resourced owners and operators of critical energy infrastructure to rapidly identify and detect the publicly exposed and vulnerable operational technology (OT) and other critical Industrial Control and Energy Delivery Systems.

Mylrea, Michael↗

Optimizing Energy For Delivery Drones - A Comprehensive Tool Set For Drone Energy Calculation And Drone Fleet Optimization

This tool is intended to be deployed for potential customers to compare the energy profiles across various drone types/classes. The primary factors considered were design of the drone, the weight of the drone, the weight of the payload, and how the drone is flown. It has energy comparison metrics like "Drone (A) vs Drone (B) ", "Drone vs Ground Vehicle", "Drone Energy from delivery via landing versus hovering". It also includes the ability to determine the number of drones and batteries needed to optimally deliver goods from a chosen location to a set of destinations.

Mendadhala, Rohit [Idaho National Laboratory (INL)↗

Data for Efficient Delivery of a DNA Aptamer-Based Biosensor into Plant Cells for Glucose Sensing through Thiol-Mediated Uptake

DNA aptamers have been widely used as biosensors for detecting a variety of targets. Despite decades of success, they have not been applied to monitor any targets in plants, even though plants are a major platform for providing oxygen, food, and sustainable products ranging from energy fuels to chemicals, and high-value products such as pharmaceuticals. A major barrier to progress is a lack of efficient methods to deliver DNA into plant cells. We herein report a thiol-mediated uptake method that more efficiently delivers DNA into Arabidopsis and tobacco leaf cells than another state-of-the-art method, DNA nanostructures. Such a method allowed efficient delivery of a glucose DNA aptamer sensor into Arabidopsis for sensing glucose. This demonstration opens a new avenue to apply DNA aptamer sensors for functional studies of various targets, including metabolites, plant hormones, metal ions, and proteins in plants for a better understanding of the biodistribution and regulation of these species and their functions.

Conversion↗

Wavelength domain spatial frequency modulation imaging: enabling fiber optic delivery and detection

Spatial frequency modulation imaging (SPIFI) provides a simple architecture for modulating an extended illumination source that is compatible with single pixel imaging. We demonstrate wavelength domain SPIFI (WD-SPIFI) by encoding time-varying spatial frequencies in the spectral domain that can produce enhanced resolution images, like its spatial domain counterpart, spatial domain (SD) SPIFI. However, contrary to SD-SPIFI, WD-SPIFI enables remote delivery by single mode fiber, which can be attractive for applications where free-space imaging is not practical. Finally, we demonstrate a cascaded system incorporating WD-SPIFI in-line with SD-SPIFI enabling single pixel 2D imaging without any beam or sample scanning.

47 OTHER INSTRUMENTATION↗

FTICR-MS, Sensor, and Environmental Data from 5 Streams Impacted by the 2020 Holiday Farm Fire Associated with: "Spatiotemporal controls on the delivery of dissolved organic matter to streams following a wildfire"

This data package is associated with the publication "Spatiotemporal Controls on the Delivery of Dissolved Organic Matter to Streams Following a Wildfire" submitted to Geophysical Research Letters (Roebuck et al., 2022). The study aims to understand storm induced transport of pyrogenic materials to streams impacted by varying degrees of burn severity. Time series samples (24 samples in 1-hour intervals) were collected at 5 sites within the McKenzie River Watershed (Oregon, USA) whose catchment were each completely engulfed by the 2020 Holiday Farm Fire. The samples were collected in November 2020 during the first major storm pulse following the conclusion of the wildfire. Samples were characterized for dissolved organic carbon, total dissolved nitrogen, and by ultra-high resolution mass spectrometry. In situ turbidity data also collected.This data package contains 4 primary folders that include the following: 1) Metadata, 2) EnvData (Environmental Data), 3) SensorData, and 4) FTICR_SupportingData. The package contains a single file-level metadata (flmd) file. Each primary folder also contains individual data dictionaries (dd) to define and provide descriptors of column/row headers and data flags. The FTICR_SupportingData, folder 4, contains raw, unprocessed FTICR-MS Data files in addition to a csv containing processed FTICR-MS data. This package contains the following file types: csv, xml, pdf.

54 ENVIRONMENTAL SCIENCES↗

Rolling Horizon Based Temporal Decomposition for the Offline Pickup and Delivery Problem with Time Windows

The offline pickup and delivery problem with time windows (PDPTW) is a classical combinatorial optimization problem in the transportation community, which has proven to be very challenging computationally. Due to the complexity of the problem, practical problem instances can be solved only via heuristics, which trade-off solution quality for computational tractability. Among the various heuristics, a common strategy is problem decomposition, that is, the reduction of a large-scale problem into a collection of smaller sub-problems, with spatial and temporal decompositions being two natural approaches. While spatial decomposition has been successful in certain settings, effective temporal decomposition has been challenging due to the difficulty of stitching together the sub-problem solutions across the decomposition boundaries. In this work, we introduce a novel temporal decomposition scheme for solving a class of PDPTWs that have narrow time windows, for which it is able to provide both fast and high-quality solutions. We utilize techniques that have been popularized recently in the context of online dial-a-ride problems along with the general idea of rolling horizon optimization. To the best of our knowledge, this is the first attempt to solve offline PDPTWs using such an approach. To show the performance and scalability of our framework, we use the optimization of paratransit services as a motivating example. Due to the lack of benchmark solvers similar to ours (i.e., temporal decomposition with an online solver), we compare our results with an offline heuristic algorithm using Google OR-Tools. In smaller problem instances (with an average of 129 requests per instance), the baseline approach is as competitive as our framework. However, in larger problem instances (approximately 2,500 requests per instance), our framework is more scalable and can provide good solutions to problem instances of varying degrees of difficulty, while the baseline algorithm often fails to find a feasible solution within comparable compute times.

Kim, Youngseo↗

Machine Learning for Slow Spill Regulation in the Fermilab Delivery Ring for Mu2e

A third-integer resonant slow extraction system is being developed for the Fermilab’s Delivery Ring to deliver protons to the Mu2e experiment. During a slow extraction process, the beam on target is liable to experience small intensity variations due to many factors. Owing to the experiment’s strict requirements in the quality of the spill, a Spill Regulation System (SRS) is currently under design. The SRS primarily consists of three components - slow regulation, fast regulation, and harmonic content tracker. In this presentation, we shall present the investigations of using Machine Learning (ML) in the fast regulation system, including further optimizations of PID controller gains for the fast regulation, prospects of an ML agent completely replacing the PID controller using supervised learning schemes such as Long Short-Term Memory (LSTM) and Gated Recurrent Unit (GRU) ML models, the simulated impact and limitation of machine response characteristics on the effectiveness of both PID and ML regulation of the spill. We also present here nascent results of Reinforcement Learning efforts, including continuous-action soft actor-critic methods, to regulate the spill rate.

43 PARTICLE ACCELERATORS↗

FPGA-Based Spill Regulation System for the Muon Delivery Ring at Fermilab

The Muon to Electron Experiment (Mu2e) requires a uniform beam profile from the Muon Delivery Ring to meet their experimental needs. A specialized Spill Regulation System (SRS) has been developed to help achieve consistent spill uniformity. The system is based on a custom-designed carrier board featuring an Arria 10 SoC, capable of executing real-time feedback control. The FPGA processes beam pulses of approximately 200 ns every 1.695 $μ$s, allowing for continuous monitoring of the extracted spill intensity through fast bunch integration. The system directly controls three quadrupole magnets, which work in conjunction with sextupole magnets to achieve third-order resonant extraction. Furthermore, the board interfaces with Fermilab's Accelerator Control Network (ACNET), enabling operators to modify spill regulation settings in real-time via the control network while providing diagnostic waveforms. These waveforms help operators monitor the process and fine-tune the feedback mechanisms. This paper presents an overview of the board's architecture and its initial progress toward regulating beam extraction. This initial version of the regulation system aims to evaluate baseline performance to inform future system improvements.

Berlioz, J. R. [Fermilab]↗

Mu2e resonant extraction regulation system simulation in delivery ring

Mu2e is an upcoming experiment at Fermilab that relies on the slowly extracted 8 GeV proton beam from the Delivery Ring. The experiment imposes strong requirements on the spill uniformity. To address these requirements, the fast spill regulations system is being developed and commissioned. To inform this development and optimize the system performance we are carrying out the detailed simulations of the regulation process. The simulation includes the effect of six harmonic sextupoles that excite the third-integer resonance and three fast ramping quadrupoles that drive the horizontal tune to 29/3. The components of spill regulation system are designed to mitigate long-term drifts in the beam, ensuring stable operation over extended timescales, as well as addresses rapid variations within single spill. In this study, we review the regulation system design, simulation of the slow regulation, and the fast regulation PID regulation to curtail random variations in the extraction rate that could occur within a single spill.

Narayanan, Aakaash [Fermilab]↗

Spatial and Temporal Analysis of the Total Cost of Ownership for Class 8 Tractors and Class 4 Parcel Delivery Trucks

The medium- and heavy-duty transportation sector is experiencing rapid changes in powertrain technology innovation, with recent announcements of battery electric and fuel cell electric trucks being offered. The economics of these alternative powertrain vehicles are uncertain and difficult to compare directly. This analysis seeks to provide a rigorous, techno-economic analysis of all of these alternative powertrain vehicles within the same analytic framework. Specifically, this report evaluates the total cost of ownership (TCO) of six different truck powertrain technologies (diesel, diesel hybrid electric, plug-in hybrid electric, compressed natural gas, battery electric, and fuel cell electric) for three different truck vocations (Class 8 long haul [750-mile range and 500-mile range], Class 8 short haul [300-mile range], and Class 4 parcel delivery [120-mile range]), for three different time frames (2018, 2025, and Ultimate).

08 HYDROGEN↗

Software-defined Networking for Energy Delivery Systems (SDN4EDS): An Architectural Blueprint (Final Report)

This is the initial version of a reference for suppliers and energy companies of all sizes to deploy networks based on software-defined networking technology (SDN) to improve reliability, reduce cyber security attack surface, and facilitate mitigation of adversarial behavior. It is a living document and will progress over the life cycle of the Software-Defined Networking for Energy Delivery Systems (SDN4EDS) project. Version 2 of this report provides information on the Red Team tabletop assessment performed against the initial reference architecture. Version 3 of this report updates the reference architecture with lessons learned from the Red Team tabletop assessment, as well as provides additional details for the use cases. It also provides information on the decision process that could be used by an organization when considering deploying SDN in their environment. The final version of this report consolidates all the interim reports generated by the project into a final report. It also draws from PNNL’s experience in deploying SDN to make recommendations on how SDN could be deployed in a utility environment, and provides rationale for those decisions allowing individual utilities to make risk-based and knowledge-based decisions on how to best deploy SDN in their own environment

97 MATHEMATICS AND COMPUTING↗

Software-defined Networking for Energy Delivery Systems (SDN4EDS): An Architectural Blueprint (Final Summary Report)

This is the initial version of a reference for suppliers and energy companies of all sizes to deploy networks based on software-defined networking technology (SDN) to improve reliability, reduce cyber security attack surface, and facilitate mitigation of adversarial behavior. It is a living document and will progress over the life cycle of the Software-Defined Networking for Energy Delivery Systems (SDN4EDS) project. Version 2 of this report provides information on the Red Team tabletop assessment performed against the initial reference architecture. Version 3 of this report updates the reference architecture with lessons learned from the Red Team tabletop assessment, as well as provides additional details for the use cases. It also provides information on the decision process that could be used by an organization when considering deploying SDN in their environment. The final version of this report consolidates all the interim reports generated by the project into a final report. It also draws from PNNL’s experience in deploying SDN to make recommendations on how SDN could be deployed in a utility environment, and provides rationale for those decisions allowing individual utilities to make risk-based and knowledge-based decisions on how to best deploy SDN in their own environment. This summary report provides a higher-level overview of the project reports. Readers interested in additional detail, including results of the Red Team assessments and the final configuration, are encouraged to read the full final report.

97 MATHEMATICS AND COMPUTING↗