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At least 253 records · Page 14
All sourcesNASA NTRSDOE OSTI
DOE OSTI2018

Molecular Epidemiology of Foot-and-Mouth Disease Virus in the Context of Transboundary Animal Movement in the Far North Region of Cameroon

Transboundary movement of animals is an important mechanism for foot-and-mouth disease virus (FMDV) spread in endemic regions, such as Cameroon. Several transboundary animal trade routes cross the Far North Region of Cameroon, and cattle moved on foot along these routes often come in contact with native (sedentary and transhumant) herds. The purpose of this study was to investigate the role of transboundary trade cattle in the epidemiology of FMDV in the Far North Region of Cameroon. A total of 582 oropharyngeal fluid (OPF) samples were collected from asymptomatic transboundary trade cattle at official border check points and 57 vesicle epithelial tissues were collected from clinically affected native cattle in the Far North Region of Cameroon during 2010–2014. Viral protein 1 (VP1) coding sequences were obtained from 6 OPF samples from transboundary cattle (4 serotype O, 2 serotype SAT2) and 19 epithelial tissue samples from native cattle (7 serotype O, 3 serotype SAT2, 9 serotype A). FMDV serotype O viruses belonged to two topotypes (East Africa-3 and West Africa), and phylogenetic analyses suggested a pattern of continuous transmission in the region. Serotype SAT2 viruses belonged to a single topotype (VII), and phylogenetic analysis suggested a pattern of repeated introductions of different SAT2 lineages in the region. Serotype A viruses belonged to topotype AFRICA/G-IV, and the pattern of transmission was unclear. Spearman rank correlation analysis of VP1 coding sequences obtained in this study from transboundary and native cattle showed a positive correlation between genetic distance and time for serotype O ( ρ = 0.71, p = 0.003) and between genetic distance and geographic distance for serotype SAT2 ( ρ = 0.54, p = 0.1). These data suggest that transboundary trade cattle participate in the transmission of FMDV in the Far North Region of Cameroon, however the dynamics and direction of transmission could not be determined in this study. Results of this study contribute to the understanding of transboundary FMDV epidemiology in Central Africa and will help to inform control programs in Cameroon and in the region.

Veterinary Sciences↗
DOE OSTI2020

Applying Two Active Acoustic Technologies to Document Presence of Large Marine Animal Targets at a Marine Renewable Energy Site

Coastal regions are highly used by humans. The growing marine renewable energy (MRE) industry will add to existing anthropogenic pressures in these regions. Regulatory bodies require animal risk assessment before new industrial activities can progress, and MRE is no exception. Preliminary data of marine mammal use of an MRE device deployment location could be informative to permitting. A combination of downlooking hydroacoustics using an echosounder and acoustic camera (imaging sonar) was used to provide a number of large targets (proxy for large fish and marine mammals) in an area of interest for MRE tidal turbine deployment in Western Passage, Maine, USA. Data were collected in May, June, August, and September of 2010 and 2011. Of the nine large targets confirmed to be animals, eight were porpoises and one was a shark. Few large targets were observed in May and June, with the majority (90%) being present in August and September of both years. The most large targets were observed when tidal current speed was less than 1 m·s−1. These data provide a preliminary assessment of large targets in a single location over sixteen 24-h surveys. The aforementioned methodology could be used for future pre- and post-installation assessments at MRE device deployment locations. Their use in concert with visual and passive acoustic monitoring can provide water depth usage by marine mammals, which is a metric that is difficult to assess with passive acoustic and visual techniques.

Staines, Garrett↗
NASA NTRS1968

Telemetry with unrestrained animals.

Telemetry with unrestrained animals, discussing radio tracking of game animals and instrumentation requirements for studying green sea turtle goal finding ability

Baldwin, H. A.↗
NASA NTRS1972

Real-time pair-feeding of animals

Automatic pair-feeding system was developed which immediately dispenses same amount of food to control animal as has been consumed by experimental animal that has free access to food. System consists of: master feeding system; slave feeding station; and control mechanism. Technique performs real time pair-feeding without attendant time lag.

Leon, H. A.↗
NASA NTRS1972

Use of the Doppler technique to track free roaming animals from satellites

The application of the Doppler effect to track wild animals is discussed, with artificial satellites used to provide wide range coverage. The limitations of radiotelemetry for the purpose of tracking animals are presented. The advantages of the artificial satellite, with specific reference to the Nimbus satellite, are examined.

Maxwell, J. C.↗
NASA NTRS1971

Bio-medical telemetry: Sensing and transmitting biological information from animals to man

The application of small radio transmitters for monitoring biological activity in animals and humans is discussed. The microminiaturization of the electronic transmitters makes it possible for them to be swallowed and to operate within the body with no external connections. The small size also makes it possible for the transmitters to be surgically implanted or carried externally to monitor specific bodily functions. The use of satellites to monitor the activity of birds and animals carrying small transmitters is described. Photographs of birds, fish, and reptiles which were equipped with miniature electronic monitors are provided.

Mackay, S.↗
NASA NTRS1972

A preliminary investigation of the environmental Control and Life Support Subsystems (EC/LSS) for animal and plant experiment payloads

A preliminary study of the environmental control and life support subsystems (EC/LSS) necessary for an earth orbital spacecraft to conduct biological experiments is presented. The primary spacecraft models available for conducting these biological experiments are the space shuttle and modular space station. The experiments would be housed in a separate module that would be contained in either the shuttle payload bay or attached to the modular space station. This module would be manned only for experiment-related tasks, and would contain a separate EC/LSS for the crew and animals. Metabolic data were tabulated on various animals that are considered useful for a typical experiment program. The minimum payload for the 30-day space shuttle module was found to require about the equivalent of a one-man EC/LSS; however, the selected two-man shuttle assemblies will give a growth and contingency factor of about 50 percent. The maximum payloads for the space station mission will require at least a seven-man EC/LSS for the laboratory colony and a nine-man EC/LSS for the centrifuge colony. There is practically no room for growth or contingencies in these areas.

Wells, H. B.↗
NASA NTRS1971

Effect of altered 'weight' upon animal tolerance to restraint.

The effect of altered weight upon animal tolerance to restraint was determined by simulating various accelerative forces with directed lead weights using restrained and nonrestrained domestic fowl (chickens). Weighting (increased weight) and conterweighting (reduced weight) produced a stressed condition - reduced relative lymphocyte counts, loss of body mass, and/or the development of a disorientation syndrome - in both restrained and nonrestrained (caged only) birds. The animal's tolerance to altered weight appeared to be a function of its body weight. Unrestrained birds were stressed by counterweighting (mean plus or minus standard error) 58.3 plus or minus 41% of their body weight, whereas restrained birds tolerated only 32.2 plus or minus 2.6% reduction in body weight. A training regimen for restrained birds was not effective in improving their tolerance to a reduced weight environment. It was concluded that domestic fowl living in a weightless (space) environment should be restrained minimally and supported by ventrally directed tension equivalent to approximately 50% of their body mass (their weight in a 1 G environment).

Burton, R. R.↗
NASA NTRS1971

Bio-medical telemetry - Sensing and transmitting biological information from animals and man.

Several examples are presented of radio transmitters swallowed, surgically implanted, or carried externally to study animal and human objects with minimum disturbance to normal activity patterns. Particular attention is given to the method of using satellite-borne receivers for determining the position of animals or other objects carrying fixed-frequency transmitters. The design and operation of the instrumentation necessary for this purpose are described.

Mackay, S.↗
NASA NTRS1972

Gravity as a factor in the animal environment.

Review of current knowledge, research, and research planning on the influence of gravity upon living organisms. Discussed factors affecting the adaptability of animals to increased acceleration fields include age, sex, posture, and body size. Affected functions and aspects reviewed cover growth and mature body size, body composition, maintenance feed requirements, and feed utilization efficiency. It is expected that research involving the exposure of animals to altered gravity states will lead to new biological concepts of very broad importance.

Smith, A. H.↗
NASA NTRS1974

Compact telemetry package for remote monitoring of neutron responses in animals

Battery-powered telemeter includes FM transmitter and is light enough to be mounted on animal's head. Animal has complete freedom of movement while its neuron responses are transmitted to receiver in laboratory. Construction may also be applied to monitor blood pressure, body temperature, and different muscular signals.

Baker, C. D.↗
NASA NTRS1975

Morphology of the internal organs in the adaptation of animals to high-altitude conditions

Disruption of metabolic processes in the walls of the blood vessels as well as changes in the functional activity of the endocrine glands play an important role in the process of an animal's accommodation to a combination of stress factors. Preliminary training of animals for stays at high-altitude markedly reduces the severity of the morphological picture.

Rakhimov, Y. A.↗
NASA NTRS1975

Continous animal exposure to a mixture of dichloromethane and 1,1,1-trichloroethane

An investigation of the effects of combined exposure of animals to dichloromethane and 1,1,1-trichloroethane was conducted using atmospheric concentrations of each solvent which had individually produced minimal measureable effects on livers. Previously established spacecraft threshold limit values for the individual solvent compounds were studied to determine validity when both were present in an astronaut's breathing environment under continuous exposure conditions. Results show that the combined effect of 90-day continuous exposure of animals to 100 ppm dichloromethane and 1000 ppm 1,1, 1-trichloroethane is no greater than the effect of each alone. While the exposed livers of mice appeared to contain slightly more fat, the degree of increased liver weight and the liver-to-body ratios are slightly lower than those measured for each solvent alone.

Source record↗
NASA NTRS1975

Computer-generated animation for analysis and design

The development of computer-generated animation techniques was reviewed and some examples of the current state of the art were described. A number of ways in which computer-generated animation can be used were examined in relation to the suitability for the engineering task at hand. The examples described are primarily concerned with attempting to combine two different types of simulation: that of superposition of an engineering design on the surrounding real world, and an evaluation of this simulation both from an engineering design and an aesthetic point of view.

Feeser, L. J.↗
NASA NTRS1979

Retainer for laboratory animals

Bio-retainer holds laboratory animals in fixed position for research and clinical experiments. Retainer allows full access to animals and can be rapidly opened and closed to admit and release specimens.

Lee, R. W.↗
NASA NTRS1977

A review of animal flight experiments

Extensive experience with biologic systems was obtained with a variety of vertebrate species over the past 18 years. Subhuman primates were precursors to man in the American space flight program; dogs and mice were animals of choice for the Soviet program. Recent attempts to use heavily instrumented animals for observations of long-term physiological effects indicate problems which must be corrected in future experiments for monitoring the effects of environmental stresses over the longer periods required for accomplishing meaningful habitation in near-Earth orbit or for travel to nearby planets.

Sandler, H.↗
NASA NTRS1977

Consideration of other primate species as flight animals

The different types of primates which might be used as flight animals are surveyed, and the pros and cons of using them are discussed. Various factors suggest that the most desirable animals for space studies are the rhesus, pig-tailed, Java, and squirrel monkeys. The capuchin monkey has assets for certain types of space experimentation.

Geoffrey H. Bourne↗
NASA NTRS1979

Coupler for surgery on small animals

Minicoupler simplifies exchange of fluids with organs of laboratory animals enabling one person to perform surgery on experimental animals such as rats and mice. Innovation eliminates obstructing hands and instruments from areas of surgery.

Johnson, J. E., Jr.↗