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At least 253 records · Page 14

Peak selection matters in Principal Component Analysis: A case study of syntrophic microbes

In situ liquid time-of-flight secondary ion mass spectrometry (ToF-SIMS) is a powerful technique to address surface characterization of living biofilms in hydrated conditions. Principal component analysis (PCA) is an important tool to process a large amount of data and interpret the information from ToF-SIMS spectra. However, ToF-SIMS data analysis is still a great challenge in complicated bacterial biofilms, because many interference peaks from the medium may result in inaccurate interpretation of ToF-SIMS spectral analysis. In this study, two syntrophic Geobacter populations were investigated using in situ liquid ToF-SIMS to reveal the biofilm surface changes between them as due to direct interspecies electron transfer (DIET). Peak overlay is an effective strategy to eliminate the matrix effects in handling complex ToF-SIMS data and was used to accomplish peak selection in this work. Both all peak and selected peak spectral PCA showed a distinctive separation among different samples. However, medium samples occupied high scores values in all peak PCA compared with the selected peak PCA, suggesting a strong interference from the medium as the matrix effect. Amino acids and lipids contributed significantly in separating all samples in selected peak PCA, which indicated that surface membrane components such as pili and proteins are important in the co-cultured Geobacter community compared to controls such as the single population planktonic cells and biofilms, respectively. Additionally, the spectral PCA results of high intensity and high resolution data obtained from liquid ToF-SIMS were compared. Selected peak PCA obtained nice separation among samples in both data sets; however, the high resolution data showed better separation between co-culture planktonics and co-culture aggregates, confirming that the higher mass accuracy is useful in analysis of microbial samples. Furthermore, amino acid and water cluster as an important media for microbial metabolite were selected for a more focused selected peak PCA comparison. Consistent scores and loadings plots were achieved. In conclusion, we show that peak selection is critical for acquiring effective microbial information and interpretation of syntrophic Geobacter using spectral data from in situ liquid ToF-SIMS.

spectral overlay, peak selection, matrix effect, P↗

Technical Note: Introduction of variance component analysis to setup error analysis in radiotherapy

Purpose: The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. Methods: Balanced data according to the one-factor random effect model were assumed. Results: Analysis-of-variance (ANOVA)-based computation was applied to estimate the values and their confidence intervals (CIs) for systematic and random errors and the population mean of setup errors. The conventional method overestimates systematic error, especially in hypofractionated settings. The CI for systematic error becomes much wider than that for random error. The ANOVA-based estimation can be extended to a multifactor model considering multiple causes of setup errors (e.g., interpatient, interfraction, and intrafraction). Conclusions: Variance component analysis may lead to novel applications to setup error analysis in radiotherapy.

60 APPLIED LIFE SCIENCES↗

Empirical Analysis of the Subjective Impressions and Objective Measures of Domain Scientists’ Visual Analytic Judgments

Scientists often use specific data analysis and presentation methods familiar within their domain. But does high familiarity drive better analytical judgment? This question is especially relevant when familiar methods themselves can have shortcomings: many visualizations used conventionally for scientific data analysis and presentation do not follow established best practices. This necessitates new methods that might be unfamiliar yet prove to be more effective. But there is little empirical understanding of the relationships between scientists’ subjective impressions about familiar and unfamiliar visualizations and objective measures of their visual analytic judgments. To address this gap and to study these factors, we focus on visualizations used for comparison of climate model performance. We report on a comprehensive survey-based user study with 47 climate scientists and present an analysis of : i) relationships among scientists’ familiarity, their perceived lev- els of comfort, confidence, accuracy, and objective measures of accuracy, and ii) relationships among domain experience, visualization familiarity, and post-study preference.

Dasgupta, Aritra↗

Temporal Analysis Of Products Statistical Analysis Processing

Temporal analysis of products statistical analysis package (tapsap) is a package for reading, cleaning, analyzing and making inference of temporal analysis of products (TAP) information. This package is designed with the intent for collaboration within the TAP community for advancing TAP analysis.

Kunz, MatthewR↗

A novel post-processing method for progressive failure analysis of brittle composite compression

Finite element analysis of brittle materials in axial compression typically uses element deletion to allow continued global deformation post-element-failure. However, element deletion produces cyclic load-displacement curves that underestimate energy absorption and are not representative of a continuum system. Two key observations support the conclusion that results from an appropriately discretized model can be an adequate representation of a continuum system. Specifically, the frequency of the oscillations in the load-displacement curve is directly dependent upon element length in the loading direction, and the peak amplitudes of oscillations are mesh size independent. A method of post-processing the analysis results, by connecting the peak amplitudes of oscillations, is proposed and applied to a series of continuous carbon fiber composite crush tubes. The load-displacement curve, stable crushing load, and specific energy absorption of the post-processed results compare well to an experimental study of crush tubes with similar layups.

Materials Science↗

Rapid depletion analysis of flowing-pebble reactor systems at equilibrium using SCALE

Several high-temperature gas-cooled reactor concepts (and more recently, salt-cooled designs such as the fluoride salt-cooled high-temperature reactor) feature core designs employing continuously circulating fuel pebbles. These reactor designs permit both continuous online refueling of fuel elements as well as higher overall achievable discharge burnups. However, rapid calculation of time-dependent fuel isotopic inventories proves challenging for this class of dynamic systems with current analysis tools. While iterative approaches employing coupled neutron transport have been developed to solve this issue, rapid depletion analysis techniques are needed to calculate time-dependent inventories for individual pebbles and batches (and thus the construction of full- core inventory at equilibrium). We propose a depletion analysis strategy for this type of system for cores at equilibrium. Drawing upon previous neutronic analysis of the PBMR-400 equilibrium core, we demonstrate the viability of developing collapsed one-group cross section libraries suitable for performing rapid depletion analyses with SCALE. (authors)

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗

Creep Analysis of Poly(ester urethane) Copolymer by Dynamic Mechanical Analysis (DMA): Melt Determination

An experiment is presented utilizing film tension, creep test dynamic mechanical analysis (DMA) to characterize the physical properties of a poly(ester urethane) block copolymer, Estane ® 5703. The polymer was pressed into a sheet from pellet form and cut into strips for analysis utilizing the TA Q800 DMA with film tension clamp. The strips were tested under five constant stress analyses from 0.125 to 0.625, at 0.125 MPa increments. Each analysis was run stepwise through a temperature gradient from 25 °C to 67 .5 °C with 2.5 °C increments, the material reached the instrument maximum displacement at different temperature steps dependent on the constant applied stress. At each of the 18 temperature steps the material was held at constant stress for 10 minutes and allowed to recover under stress-less conditions for 20 minutes. With data analysis recoverable strain data was produced and ultimately a curve of Modulus at temperature, the regression extrapolated to modulus = 0 M Pa. The extrapolated point correlated with data the weighted average melt point of the polymer measured by MDSC, within the regressive least squares fit of the measured moduli. Thereby measuring the melt temperature of a polymer by DMA. This is the third in a series of three reports 4,5 on the physical properties and degradation processes of materials used in polymer bonded explosive 9501 written for submission to the University of Oregon, Masters Industrial Internship Program.

36 MATERIALS SCIENCE↗

Cost Risk Analysis Framework (CRAFT): An Integrated Risk Analysis Tool and its Application in an Industry Use Case

This report presents the initial application design of the Cost Risk Analysis Framework Tool (CRAFT). The initial concept was formulated from a need to perform financial risk analysis that can be quickly deployable through the nuclear industry to evaluate the risk associated to capital projects and asset management. The design evolved into a framework that can integrate several forms of risk (e.g., not just financial, but also safety related) into a single analysis. In order to reduce the research and development and deployment time, we have decided to use the Risk Analysis Virtual environment (RAVEN) statistical framework as a basis for the CRAFT architecture.

97 MATHEMATICS AND COMPUTING↗

Evaluation of COTS Electronics by Power Spectrum Analysis and Multivariate Data Analysis

Power spectrum analysis (PSA) is a fast, non-destructive, sensitive method for examining commercial off-the-shelf ( COTS ) electronic components. These features make PSA attractive for both component screening and surveillance in support of component reliability efforts. Current analysis methods limit the utility of PSA due to the need to manually examine the results of analysis to identify anomalous parts. This study demonstrates the development and application of a workflow to automate the screening of COTS electronic components. Further, this study demonstrates the use of multivariate algorithms to assess aging of Zener diodes. These workflows can be readily extended to other components, combining the benefits of PSA and multivariate analysis to screen and evaluate COTS electronic components.

42 ENGINEERING↗

The Net Zero World Initiative’s Preliminary Analysis of Decarbonization Pathways for Five Countries

Under the Net Zero World Initiative, the United States is mobilizing the capabilities of nine U.S. government agencies, led by the U.S. Department of Energy (DOE), to partner with philanthropies and multiple countries to cocreate and implement tailored technical and investment pathways to accelerate the decarbonization of global energy systems. In addition, 10 of the DOE national laboratories have built a consortium housed in the Net Zero World Action Center to implement this vision by providing the deep analysis and modeling required to carry out the vision. As a whole-of-government program, the Net Zero World Initiative partners with countries committed to raising their climate ambitions by creating and implementing highly tailored, actionable technical and investment strategies that put a net-zero world within reach. The initiative enables country partners to harness the convening power and technical expertise of U.S. agencies and laboratories, international industry, and technical institutions while providing the United States an opportunity to learn from and deepen U.S. technical cooperation with key countries. This report is the first of a series, with future Phase II work being informed by ongoing consultations with the partner countries to address country pathway analysis priorities. This future work will likely include evaluating detailed technological, policy, and investment options for key sectors and for energy systems holistically. This analysis may examine in greater detail the economic and social benefits of net-zero energy transitions, including quality jobs and health outcomes, the impacts of price and supply volatility on energy investments and decisions, the risk of stranded assets, and related issues.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

Neutronics Analysis of Heating and DPA of the Proton Beam Window and Core Vessel Nozzle Neutronics Heating Analysis for the Second Target Station

This reports details the analysis of the heating rates, dpa values and He production in the Proton Beam Window (PBW) assembly and the Core Vessel (CV) nozzle for the preliminary design for the Second Target Station (STS). This analysis focuses on the heating rates in the cooled beltline component of the CV. Neutronics calculations use a detailed unstructured mesh (UM) converted from a CAD model in SpaceClaim of the PBW and CV design of February 2024. The rest of the geometry is taken from the STS master model in constructive solid geometry (CSG). Heating is evaluated for four beam profiles, which are chosen as the most likely to produce the highest heating in the beltline component. The maximum energy deposition values in the beltline are 0.02-0.08 J/cc/pulse, depending on the beam profile. Detailed point cloud data of the full UM geometry is made available for mechanical analysis. The maximum dpa rate in the beltline steel is approximately 0.02 dpa/year, which corresponds to a lifetime of 3,000 years. These results are in good agreement with previous results for the CV. For the PBW itself, maximal heating, dpa, and He production rates are very similar to the previous analysis.

43 PARTICLE ACCELERATORS↗

The Elastic Analysis Facility's (EAF's) Contribution to the Future of Analysis at Multi-Experiment Institutions and Future Colliders

The Elastic Analysis Facility (EAF) hosted at Fermi National Accelerator Laboratory (Fermilab) is a platform being developed with the goal of providing a fast and efficient facility for physics analysis. As high-energy physics moves towards collecting larger datasets, such as those from the High-Luminosity LHC, the EAF strives to provide a powerful and adaptable framework for future colliders and multi-experiment institutions. Currently, the EAF supports several experiments including CMS, NOvA, and DUNE as well as serving accelerator physicists and beam line operations through integrated software and secure connections to Fermilab's computing resources. In addition, the EAF was designed with a user-friendly interface, intended to be more intuitive for emerging generations of physicists, that is still accessible for established styles of analysis. The EAF can also achieve better analysis efficiency due to the modernization of software and tools that can better utilize Fermilab's computing power. Furthermore, its design incorporates industry standards whenever possible, enhancing its sustainability and making it a possible template for other national or international laboratories and research facilities. Overall, the EAF is a forward-looking solution that will meet the evolving needs of particle physics, ensuring readiness for future colliders and multi-experiment research institutions.

Chavez, Elise [Wisconsin U., Madison]↗

An interdisciplinary analysis of ERTS data for Colorado mountain environments using ADP techniques. An early analysis of ERTS-1 data

There are no author-identified significant results in this report. The principal problem encountered has been the lack of good quality, small scale baseline photography for the test areas. Analysis of the ERTS-1 data for the San Juan Site will emphasize development of a preliminary spectral classification defining grass cover categories, and then selection of subframes for intensive investigation of the forestry, geologic, and hydrologic properties of the area. Primary work has been devoted to the selection and digitization of areas for topographic modeling, and compilation of ground based data maps necessary for computer analysis. Study effort has emphasized: geomorphic features; macro-vegetation; micro-vegetation; snow-hydrology; insect/disease damage; and blow-down. Analysis of a frame of the Lake Texoma area indicates a great deal of potential in the analysis and interpretation of ERTS imagery. Preliminary results of investigations of geologic, forest, range, cropland, and water resources of the area are summarized.

Hoffer, R. M.↗

F-111 natural laminar flow glove flight test data analysis and boundary layer stability analysis

An analysis of 34 selected flight test data cases from a NASA flight program incorporating a natural laminar flow airfoil into partial wing gloves on the F-111 TACT airplane is given. This analysis determined the measured location of transition from laminar to turbulent flow. The report also contains the results of a boundary layer stability analysis of 25 of the selected cases in which the crossflow (C-F) and Tollmien-Schlichting (T-S) disturbance amplification factors are correlated with the measured transition location. The chord Reynolds numbers for these cases ranges from about 23 million to 29 million, the Mach numbers ranged from 0.80 to 0.85, and the glove leading-edge sweep angles ranged from 9 deg to 25 deg. Results indicate that the maximum extent of laminar flow varies from 56% chord to 9-deg sweep on the upper surface, and from 51% chord at 16-deg sweep to 6% chord at 25-deg sweep on the lower. The results of the boundary layer stability analysis indicate that when both C-F and T-S disturbances are amplified, an interaction takes place which reduces the maximum amplification factor of either type of disturbance that can be tolerated without causing transition.

Runyan, L. J.↗

Development of a special-purpose test surface guided by uncertainty analysis - Introduction of a new uncertainty analysis step

Development of a recent experimental program to investigate the effects of streamwise curvature on boundary layer transition required making a bendable, heated and instrumented test wall, a rather nonconventional surface. The present paper describes this surface, the design choices made in its development and how uncertainty analysis was used, beginning early in the test program, to make such design choices. Published uncertainty analysis techniques were found to be of great value; but, it became clear that another step, one herein called the pre-test analysis, would aid the program development. Finally, it is shown how the uncertainty analysis was used to determine whether the test surface was qualified for service.

Wang, T.↗

Space Shuttle Main Engine structural analysis and data reduction/evaluation. Volume 2: High pressure oxidizer turbo-pump turbine end bearing analysis

The high-pressure oxidizer turbopump (HPOTP) consists of two centrifugal pumps, on a common shaft, that are directly driven by a hot-gas turbine. Pump shaft axial thrust is balanced in that the double-entry main inducer/impeller is inherently balanced and the thrusts of the preburner pump and turbine are nearly equal but opposite. Residual shaft thrust is controlled by a self-compensating, non-rubbing, balance piston. Shaft hang-up must be avoided if the balance piston is to perform properly. One potential cause of shaft hang-up is contact between the Phase 2 bearing support and axial spring cartridge of the HPOTP main pump housing. The status of the bearing support/axial spring cartridge interface is investigated under current loading conditions. An ANSYS version 4.3, three-dimensional, finite element model was generated on Lockheed's VAX 11/785 computer. A nonlinear thermal analysis was then executed on the Marshall Space Flight Center Engineering Analysis Data System (EADS). These thermal results were then applied along with the interference fit and bolt preloads to the model as load conditions for a static analysis to determine the gap status of the bearing support/axial spring cartridge interface. For possible further analysis of the local regions of HPOTP main pump housing assembly, detailed ANSYS submodels were generated using I-DEAS Geomod and Supertab (Appendix A).

Sisk, Gregory A.↗

Reflector surface distortion analysis techniques (thermal distortion analysis of antennas in space)

A group of large computer programs are used to predict the farfield antenna pattern of reflector antennas in the thermal environment of space. Thermal Radiation Analysis Systems (TRASYS) is a thermal radiation analyzer that interfaces with Systems Improved Numerical Differencing Analyzer (SINDA), a finite difference thermal analysis program. The programs linked together for this analysis can now be used to predict antenna performance in the constantly changing space environment. They can be used for very complex spacecraft and antenna geometries. Performance degradation caused by methods of antenna reflector construction and materials selection are also taken into consideration. However, the principal advantage of using this program linkage is to account for distortions caused by the thermal environment of space and the hygroscopic effects of the dry-out of graphite/epoxy materials after the antenna is placed into orbit. The results of this type of analysis could ultimately be used to predict antenna reflector shape versus orbital position. A phased array antenna distortion compensation system could then use this data to make RF phase front corrections. That is, the phase front could be adjusted to account for the distortions in the antenna feed and reflector geometry for a particular orbital position.

Sharp, R.↗

Asymptotic modal analysis and statistical energy analysis

The sound field of a structural-acoustic enclosure was subject to experimental analysis and theoretical description in order to develop an efficient and accurate method for predicting sound pressure levels in enclosures such as aircraft fuselages. Asymptotic Modal Analysis (AMA) is the method under investigation. AMA is derived from classical modal analysis (CMA) by considering the asymptotic limit of the sound pressure level as the number of acoustic and/or structural modes approaches infinity. Using AMA, results identical to those of Statistical Energy Analysis (SEA) were obtained for the spatially-averaged sound pressure levels in the interior. AMA is systematically derived from CMA and therefore the degree of generality of the end result can be adjusted through the choice of appropriate simplifying assumptions. For example, AMA can be used to obtain local sound pressure levels at particular points inside the enclosure, or to include the effects of varying the size and/or location of the sound source. AMA theoretical results were compared with CMA theory and also with experiment for the case where the structural-acoustic enclosure is a rectangular cavity with part of one wall flexible and vibrating, while the rest of the cavity is rigid.

Dowell, Earl H.↗