Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “AMPLIFICATION”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 253 records · Page 14
All sourcesNASA NTRSDOE OSTI
DOE OSTI2019

Laser Amplification in Strongly Magnetized Plasma

In this work, we consider backscattering of laser pulses in strongly magnetized plasma mediated by kinetic magnetohydrodynamic waves. Magnetized low-frequency (MLF) scattering, which can occur when the external magnetic field is neither perpendicular nor parallel to the laser propagation direction, provides an instability growth rate higher than Raman scattering and a frequency downshift comparable to Brillouin scattering. In addition to the high growth rate, which allows smaller plasmas, and the 0.1%–2% frequency downshift, which permits a wide range of pump sources, MLF scattering is an ideal candidate for amplification because the process supports an exceptionally large bandwidth, which particle-in-cell simulations show produces ultrashort durations. Under some conditions, MLF scattering also becomes the dominant spontaneous backscatter instability, with implications for magnetized laser-confinement experiments.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2021

Magnetic Field Amplification by a Nonlinear Electron Streaming Instability

Magnetic field amplification by relativistic streaming plasma instabilities is central to a wide variety of high-energy astrophysical environments as well as to laboratory scenarios associated with intense lasers and electron beams. We report on a new secondary nonlinear instability which arises for relativistic dilute electron beams after the saturation of the linear Weibel instability. This instability grows due to the transverse magnetic pressure associated with the beam current filaments, which cannot be quickly neutralized due to the inertia of background ions. We show that it can amplify the magnetic field strength and spatial scale by orders of magnitude, leading to large-scale plasma cavities with strong magnetic field and to very efficient conversion of the beam kinetic energy into magnetic energy. The instability growth rate, saturation level, and scale length are derived analytically and shown to be in good agreement with fully-kinetic simulations.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2022

Femtosecond-Terawatt Hard X-Ray Pulse Generation with Chirped Pulse Amplification on a Free Electron Laser

Advances of high intensity lasers have opened up the field of strong field physics and led to a broad range of technological applications. Recent x ray laser sources and optics development makes it possible to obtain extremely high intensity and brightness at x ray wavelengths. In this paper, we present a system design that implements chirped pulse amplification for hard x ray free electron lasers. Numerical modeling with realistic experimental parameters show that near-transform-limit single-femtosecond hard x ray laser pulses with peak power exceeding 1 TW and brightness exceeding 4×10 35 s -1 mm -2 mrad -2 0.1\%bandwdith -1 can be consistently generated. In conclusion, realization of such beam qualities is essential for establishing systematic and quantitative understanding of strong field x-ray physics and nonlinear x ray optics phenomena.

47 OTHER INSTRUMENTATION↗
DOE OSTI2024

Robust Quantum Control via Multipath Interference for Thousandfold Phase Amplification in a Resonant Atom Interferometer

We introduce a novel technique for enhancing the robustness of light-pulse atom interferometers against the pulse infidelities that typically limit their sensitivities. The technique uses quantum optimal control to favorably harness the multipath interference of the stray trajectories produced by imperfect atom-optics operations. We apply this method to a resonant atom interferometer and achieve thousandfold phase amplification, representing a 50-fold improvement over the performance observed without optimized control. Moreover, we find that spurious interference can arise from the interplay of spontaneous emission and many-pulse sequences and demonstrate optimization strategies to mitigate this effect. Given the ubiquity of spontaneous emission in quantum systems, these results may be valuable for improving the performance of a diverse array of quantum sensors. We anticipate our findings will significantly benefit the performance of matter-wave interferometers for a variety of applications, including dark matter, dark energy, and gravitational wave detection.

47 OTHER INSTRUMENTATION↗
DOE OSTI2025

Floquet engineering of polaritonic amplification in dispersive photonic time crystals

In this study, we investigate the dynamics of dispersive photonic time crystals (PTCs) and their potential applications for controlling light-matter interaction. Using the Lorentz-Drude as dispersive material model, we analyze the effects of periodic modulation of dispersion parameters through both theoretical and numerical analysis, revealing the emergence of hybrid bandgaps from the interaction of polaritonic branches with distinctive characteristics. Our study demonstrates that dispersive PTCs offer novel excitation channels and amplification possibilities, that require lower modulation frequencies compared to nondispersive systems thus alleviating experimental challenges for the realization of PTCs in the optical regime. These findings pave the way for advancements in polaritonic lasing and resonant Raman scattering.

Classical optics↗
DOE OSTI2025

Amplification of laser imprint in the presence of strong, externally imposed, target-normal magnetic fields

Here, an experiment was performed on the OMEGA EP Laser System to investigate the effects of magnetic fields on laser imprint. A 30 µ⁢m thick CH target was driven by a single beam delivering 3.0 kJ of UV energy in a 5 ns square pulse without smoothing by spectral dispersion. The Rayleigh-Taylor amplification of this beam's imprint on the target surface was monitored using face-on gated x-ray radiography from a Gd backlighter. Magnetic fields of up to 45 T were applied normal to the target surface. Analysis of the resulting radiographs shows a 60 ± 13% increase in the spectrally resolved surface perturbation amplitudes, consistent at all times and for all unsaturated frequencies. This consistency indicates that the increase in perturbation amplitudes was due to a change in the initial amplitudes rather than Rayleigh-Taylor growth. This is supported by the trajectory of individual modes and the inferred time-averaged perturbation growth rates. Laser imprint is therefore inferred to have increased due to strong magnetic fields that remain in the conduction zone of the target, suppressing off-axis electron motion and limiting the effects of thermal smoothing.

direct drive↗
DOE OSTI2020

Characterization of Amplification Properties of the Superconducting-Ferromagnetic Transistor

Here we report on the measurement results of the superconducting-ferromagnetic transistors (SFTs). The devices were made at Northwestern University and Hypres (SeeQC), Inc. (Nevirkovets et al., 2014; 2015). SFT is a multiterminal device with the SIS'FIFS (or SFIFS'IS) structure (where S, I, and F denote a superconductor, an insulator, and a ferromagnetic material, respectively) exploiting intense quasiparticle injection in order to modify the nonlinear I-V curve of a superconducting tunnel junction. SFT is capable of providing voltage, current, and power amplification while having good input/output isolation. We characterized the devices using different measurement techniques. We measured S parameters of the single- and double-acceptor devices at frequencies up to 5 MHz. Importantly, we confirmed that the isolation between the input and output of the device is quite good. However, the techniques typically employed to characterize semiconductor devices do not allow for revealing the full potential of our low-resistive SFT devices, especially those having two acceptors. In the latter case, we also tested the devices using the battery-powered current sources with floating grounds. Analyzing double-acceptor I-V curves recorded at different levels of injection currents, for an optimal load, we deduced a small-signal voltage gain of 33 and a power gain of 2.4. We suggest that further improvement of the SFT device parameters is possible in optimized devices, so that the device potentially may serve as a preamplifier for readout of output signals of cryogenic detectors and be useful as an element of other superconductor-based circuits. In addition, we used scanning transmission electron microscopy to identify some problems in the fabrication of the devices without any planarization.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗
DOE OSTI2017

Identifying the plant-associated microbiome across aquatic and terrestrial environments: the effects of amplification method on taxa discovery

Plants in terrestrial and aquatic environments contain a diverse microbiome. Yet, the chloroplast and mitochondria organelles of the plant eukaryotic cell originate from free-living cyanobacteria and Rickettsiales. This represents a challenge for sequencing the plant microbiome with universal primers, as ~99% of 16S rRNA sequences may consist of chloroplast and mitochondrial sequences. Peptide nucleic acid clamps offer a potential solution by blocking amplification of host-associated sequences. We assessed the efficacy of chloroplast and mitochondria-blocking clamps against a range of microbial taxa from soil, freshwater and marine environments. While we found that the mitochondrial blocking clamps appear to be a robust method for assessing animal-associated microbiota, Proteobacterial 16S rRNA binds to the chloroplast-blocking clamp, resulting in a strong sequencing bias against this group. We attribute this bias to a conserved 14-bp sequence in the Proteobacteria that matches the 17-bp chloroplast-blocking clamp sequence. By scanning the Greengenes database, we provide a reference list of nearly 1500 taxa that contain this 14-bp sequence, including 48 families such as the Rhodobacteraceae, Phyllobacteriaceae, Rhizobiaceae, Kiloniellaceae and Caulobacteraceae. To determine where these taxa are found in nature, we mapped this taxa reference list against the Earth Microbiome Project database. These taxa are abundant in a variety of environments, particularly aquatic and semiaquatic freshwater and marine habitats. To facilitate informed decisions on effective use of organelle-blocking clamps, we provide a searchable database of microbial taxa in the Greengenes and Silva databases matching various n-mer oligonucleotides of each PNA sequence.

Jackrel, Sara L.↗
DOE OSTI2023

In situ amplification of spin echoes within a kinetic inductance parametric amplifier

The use of superconducting microresonators together with quantum-limited Josephson parametric amplifiers has enhanced the sensitivity of pulsed electron spin resonance (ESR) measurements by more than four orders of magnitude. So far, the microwave resonators and amplifiers have been designed as separate components due to the incompatibility of Josephson junction–based devices with magnetic fields. This has produced complex spectrometers and raised technical barriers toward adoption of the technique. Here, we circumvent this issue by coupling an ensemble of spins directly to a weakly nonlinear and magnetic field–resilient superconducting microwave resonator. We perform pulsed ESR measurements with a 1-pL mode volume containing 6 × 10 7 spins and amplify the resulting signals within the device. When considering only those spins that contribute to the detected signals, we find a sensitivity of 2.8 x 10 3 spins / $\sqrt{Hz}$ for a Hahn echo sequence at a temperature of 400 mK. In situ amplification is demonstrated at fields up to 254 mT, highlighting the technique’s potential for application under conventional ESR operating conditions.

42 ENGINEERING↗
DOE OSTI2017

Amplification of terahertz radiation in a plasmon n–i–p–i graphene structure with charge-carrier injection

The absorption/amplification spectrum of terahertz radiation in inhomogeneous graphene (n–i–p–i structure) with a periodic dual metal grating is theoretically investigated. It is shown that the amplification of terahertz radiation sharply increases at the plasmon-resonance frequency, when losses due to electron scattering and emission are balanced by the plasmon gain (related to the stimulated radiative interband recombination of electron–hole pairs in the inverted region of graphene).

36 MATERIALS SCIENCE↗
DOE OSTI2018

Photoconductivity Amplification in a Type-II n-GaSb/InAs/p-GaSb Heterostructure with a Single QW

Significant photocurrent/photoconductivity amplification is observed at low reverse biases in a type-II n-GaSb/InAs/p-GaSb heterostructure with a single quantum well (QW), grown by metal-organic vapor phase epitaxy. A sharp increase in the photocurrent by more than two orders of magnitude occurs under exposure of the heterostructure to monochromatic light with a wavelength of 1.2–1.6 μm (at 77 K) and the application of a reverse bias in the range 5–200 mV. The optical gain depends on the applied voltage and increases to 2.5 × 10{sup 2} at a reverse bias of 800 mV. Theoretical analysis demonstrated that the main role in the phenomenon is played by the screening of the external electric field by electrons accumulated in the deep InAs QW and by the mechanism of the tunneling transport of carriers with a small effective mass. It is shown that the effect under study is common to both isotype and anisotype type-II heterojunctions, including structures with QWs and superlattices.

36 MATERIALS SCIENCE↗
DOE OSTI2014

Multiplex Degenerate Primer Design for Targeted Whole Genome Amplification of Many Viral Genomes

Background . Targeted enrichment improves coverage of highly mutable viruses at low concentration in complex samples. Degenerate primers that anneal to conserved regions can facilitate amplification of divergent, low concentration variants, even when the strain present is unknown. Results . A tool for designing multiplex sets of degenerate sequencing primers to tile overlapping amplicons across multiple whole genomes is described. The new script, run_tiled_primers, is part of the PriMux software. Primers were designed for each segment of South American hemorrhagic fever viruses, tick-borne encephalitis, Henipaviruses, Arenaviruses, Filoviruses, Crimean-Congo hemorrhagic fever virus, Rift Valley fever virus, and Japanese encephalitis virus. Each group is highly diverse with as little as 5% genome consensus. Primer sets were computationally checked for nontarget cross reactions against the NCBI nucleotide sequence database. Primers for murine hepatitis virus were demonstrated in the lab to specifically amplify selected genes from a laboratory cultured strain that had undergone extensive passage in vitro and in vivo. Conclusions . This software should help researchers design multiplex sets of primers for targeted whole genome enrichment prior to sequencing to obtain better coverage of low titer, divergent viruses. Applications include viral discovery from a complex background and improved sensitivity and coverage of rapidly evolving strains or variants in a gene family.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2025

Extrapolar Cloud Feedbacks as a Driver of Arctic Amplification

The role of cloud feedbacks in Arctic amplification (AA) of anthropogenic warming remains unclear. Traditional feedback analysis diagnoses the net cloud feedback as strongly positive in the tropics but either weak or negative in the Arctic, suggesting that AA would be amplified if cloud feedbacks were suppressed. However, in cloud-locking experiments using the slab ocean version of the Energy Exascale Earth System Model (E3SM), we find that suppressing cloud feedbacks results in a substantial decrease in AA under greenhouse gas forcing. We show that the increase in AA from cloud feedbacks arises from two main mechanisms: 1) the additional energy contributed by positive cloud feedbacks in the tropics leads to increased poleward moist atmospheric heat transport (AHT) which then amplifies Arctic warming; and 2) the additional Arctic warming is amplified by positive noncloud feedbacks in the region, together making extrapolar cloud feedbacks amplify AA. We also find that cloud changes can modify the strength of noncloud feedback, but that modification has a small effect on Arctic warming. We further examine the role of cloud feedbacks in AA using a moist energy balance model, which demonstrates that interactions of cloud feedbacks with moist AHT and other positive feedbacks dominate the influence of clouds on the pattern of surface warming. However, the contribution of cloud-induced changes in noncloud feedbacks on AA is relatively minor. Furthermore, these results demonstrate that traditional attributions of AA, that are based on local feedback analysis, overlook key interactions between extrapolar cloud changes, poleward AHT, and noncloud feedbacks in the Arctic.

58 GEOSCIENCES↗
DOE OSTI2019

On loss compensation, amplification and lasing in metallic metamaterials

The design of metamaterials, which are artificial materials that can offer unique electromagnetic properties, is based on the excitation of strong resonant modes. Unfortunately, material absorption—mainly due to their metallic parts—can damp their resonances and hinder their operation. Incorporating a gain material can balance these losses, but this must be performed properly, as a reduced or even eliminated absorption does not guarantee loss compensation. Here we examine the possible regimes of interaction of a gain material with a passive metamaterial and show that background amplification and loss compensation are two extreme opposites, both of which can lead to lasing.

36 MATERIALS SCIENCE↗
DOE OSTI2016

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

Background: High mitotic activity is associated with the genesis and progression of many cancers. Small molecule inhibitors of mitotic apparatus proteins are now being developed and evaluated clinically as anticancer agents. With clinical trials of several of these experimental compounds underway, it is important to understand the molecular mechanisms that determine high mitotic activity, identify tumor subtypes that carry molecular aberrations that confer high mitotic activity, and to develop molecular markers that distinguish which tumors will be most responsive to mitotic apparatus inhibitors. Methods: We identified a coordinately regulated mitotic apparatus network by analyzing gene expression profiles for 53 malignant and non-malignant human breast cancer cell lines and two separate primary breast tumor datasets. We defined the mitotic network activity index (MNAI) as the sum of the transcriptional levels of the 54 coordinately regulated mitotic apparatus genes. The effect of those genes on cell growth was evaluated by small interfering RNA (siRNA). Results: High MNAI was enriched in basal-like breast tumors and was associated with reduced survival duration and preferential sensitivity to i nhibitors of the mitotic apparatus proteins, polo-like kinase, centromere associated protein E and aurora kinase designated GSK462364, GSK923295 and GSK1070916, respectively. Co-amplification of regions of chromosomes 8q24, 10p15-p12, 12p13, and 17q24-q25 was associated with the transcriptional upregulation of this network of 54 mitotic apparatus genes, and we identify transcription factors that localize to these regions and putatively regulate mitotic activity. Knockdown of the mitotic network by siRNA identified 22 genes that might be considered as additional therapeutic targets for this clinically relevant patient subgroup. Conclusions: We define a molecular signature which may guide therapeutic approaches for tumors with high mitotic network activity.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2019

Simulation of grating compressor misalignment tolerances and mitigation strategies for chirped-pulse–amplification systems of varying bandwidths and beam sizes

Here, the effects of pulse compressor grating misalignment on the pulse duration and focusability are simulated for chirped-pulse–amplification systems of varying bandwidth, beam size, groove density, and incident angle. Tilt-alignment tolerances are specified based on a √2 drop in focused intensity, illustrating how tolerances scale with bandwidth and compressor beam size, which scales with energy when transformed via known grating damage thresholds. Grating-alignment tolerance scaling with grating groove density and incident/diffracted angles is investigated and applied to compressor design. A correlation between grating tip and in-plane rotation error sensitivity is defined and used to compensate residual out-of-plane angular dispersion, even for ultra-broadband pulses. Simulation of dispersion compensation methods after grating misalignment are shown to mitigate pulse lengthening, limited by temporal contrast degradation and higher-order effects for ultrabroad bandwidths.

47 OTHER INSTRUMENTATION↗
DOE OSTI2021

Analysis of pump-to-signal noise transfer in two-stage ultra-broadband optical parametric chirped-pulse amplification

In optical parametric chirped-pulse amplification (OPCPA), pump temporal intensity modulation is transferred to the chirped-signal spectrum via instantaneous parametric gain and results in contrast degradation of the recompressed signal. We investigate, for the first time to our knowledge, the pump-to-signal noise transfer in a two-stage ultra-broadband OPCPA pumped by a single laser and show the dependence of pump-induced signal noise, characterized both before and after pulse compression, on the difference in pump-seed delay in the two stages. We demonstrate an up-to-15-dB reduction of the pump-induced contrast degradation via pump-seed delay optimization. Experiments and simulations show that, even when parametric amplifiers are operated in saturation, the pump-seed delay can be used to minimize the pump-induced contrast degradation that is attributed largely to the noises from the unsaturated edges of the pulse and that of the beam.

47 OTHER INSTRUMENTATION↗