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At least 235 records · Page 13

Microvascular responses to body tilt in cutaneous maximus muscle of conscious rats

We investigated microvascular responses to head-up tilt (HUT) and head-down tilt (HDT) in striated muscle of conscious male rats. To observe the microcirculation in the cutaneous maximus muscle, a transparent polycarbonate chamber was implanted aseptically into a skin fold created between the shoulders. Rats were trained to sit quietly during HUT and HDT while positioned on a horizontal microscope that rotated in the sagittal plane. At 4-5 days after surgery, arteriole and venule diameters were recorded using videomicroscopy while the rat experienced 10 min each (in random order) of HUT or HDT at 20 deg or 40 deg separated by 2-h rest periods. HUT had no affect on microvessel diameter; 20 deg HDT had little affect. In response to 40 deg HDT, 'large' arterioles constricted by 18 +/- 2% and 'small' arterioles dilated by 21 +/- 3%; this difference suggested variation in mechanisms controlling arteriolar responses. Venules exhibited a larger fluctuation in diameter during 40 deg HDT compared with other body positions, suggesting that venomotor activity may be induced with sufficient fluid shift or change in central venous pressure. These observations illustrate a viable model for studying microvascular responses to gravitational stress in conscious rats.

Puri, Rohit K.↗

Tilting A Small Reflector For Vernier Pointing Of A Large Antenna

Simple vernier pointing technique devised to facilitate scanning beam pointing of large paraboloidal reflector so line of sight of antenna sweeps out narrow cone about fixed axis (conical scan, also known as "conscan" in art). Scan effected by one of relatively small beam-waveguide reflectors or mirrors that couple signals between antenna and distant transmitting and/or receiving electronic circuits. Easier to tilt small mirror than to tilt massive antenna structure.

Veruttipong, Watt↗

Variable-Tilt Helicopter Rotor Mast

Variable-tilt helicopter rotor mast proposed to improve helicopter performance and reduce vibration, especially at upper end of forward-speed range of helicopters. Achieved by use of universal coupling in main rotor mast or by tilting entire engine-and-transmission platform. Performance, energy efficiency, and safety enhanced.

Kelley, Henry L.↗

The tilts of corotating interaction regions at mid heliographic latitudes

Ulysses observations of corotating interaction regions (CIRs) at mid heliographic latitudes have shown that the flow downstream of the forward shock (or wave) on the leading edge of a CIR generally turns northward and westward, while the flow downstream of the reverse wave on the trailing edge generally turns southward and eastward. These systematic flow deflections are a natural consequence of large scale pressure gradients associated with the CIRs, and indicate that the forward waves tend to propagate toward and across the equator with increasing heliocentric distance, while the reverse waves tend to propagate toward the pole. Recent determinations of CIR shock normals using the Ulysses magnetic field data appear to confirm these plasma results (Burton, private communication). Numerical simulations indicate that these effects (which imply that CIRs are systematically tilted in the north-south direction at mid latitudes) are a natural consequence of the tilt of the solar magnetic dipole axis relative to the solar rotation axis. The present work utilizes a variety of techniques to analyze the flow deflections observed within CIRs from which we can infer the overall orientations of the CIRs and the speeds and directions of propagation of the waves. Where possible, the observations are quantitatively compared with the results of 3-dimensional MHD simulations.

Riley, Pete↗

Calf venous compliance measured with head-up tilt equals supine calf compliance

Elevated calf compliance may contribute to orthostatic intolerance following space flight and bed rest. Calf venous compliance is measured conventionally with venous occlusion plethysmography in supine subjects. With this well-established technique, subjects undergo inflation of a pressure cuff around the thigh just above the knee, which increases calf venous pressure. A plethysmograph simultaneously measures calf volume elevation. Compliance equals calf volume elevation per mm Hg thigh occlusion (calf venous) pressure in relaxed legs of the supine subjects. Compliance may also be measured during stepwise head-up tilt (HUT) as calf volume elevation per mm Hg gravitational venous pressure elevation produced by HUT. However, during HUT on a tilt table with a footplate, calf muscles activate to counteract gravity: this is an obvious and natural response to gravitational force. Such muscle activation conceivably could reduce calf compliance, yet relatively little calf muscle activation occurs during HUT and orthostasis (less than 10% of maximal voluntary levels; 4, 8, 10). Also, this activation produces minimal calf volume change (less than 0.3%; 3). Therefore, we hypothesized that calf compliance measured with HUT equals that measured with supine venous occlusion.

Watenpaugh, D. E.↗

Large-Scale Wind-Tunnel Tests of an Airplane Model with an Unswept, Tilt Wing of Aspect Ratio 5.5, and with Four Propellers and Blowing Flaps

Tests were made of a large-scale tilt-wing deflected-slipstream VTOL airplane with blowing-type BLC trailing-edge flaps. The model was tested with flap deflections of 0 deg. without BLC, 50 deg. with and without BLC, and 80 deg. with BLC for wing-tilt angles of 0, 30, and 50 deg. Included are results of tests of the model equipped with a leading-edge flap and the results of tests of the model in the presence of a ground plane.

Weiberg, James A.↗

Wind-Tunnel Investigation of a Small-Scale Model of an Aerial Vehicle Supported by Tilting Ducted Fans

A wind-tunnel investigation has been made to study the static longitudinal and lateral stability characteristics of a simplified aerial vehicle supported by ducted fans that tilt relative to the airframe. The ducts were in a triangular arrangement with one duct in front and two at the rear in order to minimize the influence of the downwash of the front duct on the rear ducts. The results of the investigation were compared with those of a similar investigation for a tandem two-duct arrangement in which the ducts were fixed (rather than tiltable) relative to the airframe, since the three-duct configuration had been devised in an attempt to avoid some of the deficiencies of the tandem fixed-duct configuration. The results of the investigation indicated that the tilting-duct arrangement had less noseup pitching moment for a given forward speed than the tandem fixed-duct arrangement. The model had less angle-of-attack instability than the tandem fixed-duct arrangement. The model was directionally unstable but had a positive dihedral effect throughout the test speed range.

Smith, Charles C., Jr.↗

Flight Investigation of the Stability and Control Characteristics of a 1/4-Scale Model of a Tilt-Wing Vertical-Take-Off-and-Landing Aircraft

An experimental investigation has been conducted to determine the dynamic stability and control characteristics of a tilt-wing vertical-take-off-and-landing aircraft with the use of a remotely controlled 1/4-scale free-flight model. The model had two propellers with hinged (flapping) blades mounted on the wing which could be tilted up to an incidence angle of nearly 90 deg for vertical take-off and landing. The investigation consisted of hovering flights in still air, vertical take-offs and landings, and slow constant-altitude transitions from hovering to forward flight. The stability and control characteristics of the model were generally satisfactory except for the following characteristics. In hovering flight, the model had an unstable pitching oscillation of relatively long period which the pilots were able to control without artificial stabilization but which could not be considered entirely satisfactory. At very low speeds and angles of wing incidence on the order of 70 deg, the model experienced large nose-up pitching moments which severely limited the allowable center-of-gravity range.

Tosti, Louis P.↗

Force-Test Investigation of the Stability and Control Characteristics of a 1/4-Scale Model of a Tilt-Wing Vertical-Take-Off-and-Landing Aircraft

A wind-tunnel investigation has been made to determine the aerodynamic characteristics of a 1/4-scale model of a tilt-wing vertical-take-off-and-landing aircraft. The model had two 3-blade single-rotation propellers with hinged (flapping) blades mounted on the wing, which could be tilted from an incidence of 4 deg for forward flight to 86 deg for hovering flight. The investigation included measurements of both the longitudinal and lateral stability and control characteristics in both the normal forward flight and the transition ranges. Tests in the forward-flight condition were made for several values of thrust coefficient, and tests in the transition condition were made at several values of wing incidence with the power varied to cover a range of flight conditions from forward-acceleration (or climb) conditions to deceleration (or descent) conditions The control effectiveness of the all-movable horizontal tail, the ailerons and the differential propeller pitch control was also determined. The data are presented without analysis.

Newsom, William A., Jr.↗

Tilt Modulation Distortions in Wave Topography Measured by a Scanning Radar Altimeter

Work continues on estimating tilt modulation distortions in the wave topography measured by a scanning radar altimeter. To quantify this effect, a two-dimensional simulation has been performed in the cross-track plane only which assumed that sinusoidal waves of constant wavelength propagate in the cross-track direction (and are infinitely long-crested in the along-track direction). The initial results reported earlier for a Gaussian surface scattering model indicated that when the highest reasonable value of mss is used in the simulation (the Plant limit of 0.08), the nadir values of the ratio of the apparent to actual wave height are the same as for the omnidirectional scattering case. But as the off-nadir angle increased, the apparent wave height increased and became larger than the actual wave height by about 10 degrees off-nadir. And the shorter the wavelength, the larger the apparent wave height increase. This represented a systematic over-estimate of the wave amplitude for waves propagating in the cross-track direction. For lower values of mss the situation worsened. The simulation has been improved by incorporating actual variations of backscattered power with incidence angle measured by the SRA instead of the Gaussian model. The resulting distortion was about half that originally reported. The 3-dimensional simulation to model waves propagating at various azimuthal angles relative to the cross-track plane is still in progress. The results of this model will be verified by comparing them with Scanning Radar Altimeter (SRA) data and optimum correction procedures will be developed. An assessment of the improved 2-dimensional model indicates that the distortion will generally be small in the data taken during the Southern Ocean Waves Experiment (SOWEX) presently be analyzed. But tilt modulation effects are of great concern for SRA data collected during the 1998 hurricane season since the minimum aircraft altitude was 1.5 km and it frequently flew higher. For a given wave length and steepness, the effect increases with increasing aircraft altitude, and is larger for waves propagating in the cross-track direction, which was generally the situation during the hurricane flights.

Walsh, Edward J.↗

Peripheral Microvascular Responses to Whole-Body Tilting, G(z) Centrifugation, and Lower Body Negative Pressure Stresses in Humans

The response of the cutaneous microcirculation to orthostatic stress varies along the length of the body due to the interaction of central controls with regional responses to local blood pressure. We hypothesize that artificial orthostatic stresses such as Gz centrifugation and LBNP differ from whole-body tilting in terms of the distribution of microvascular blood flow. Cutaneous microvascular flows were measured by laser Doppler flowmetry at the neck, thigh, and leg of 15 normal subjects. Volunteers underwent stepwise head-up tilt (HUT) and short- and long-arm centrifugation protocols from supine control (0 Gz) to 0.2, 0.4, 0.6, 0.8, 1.0, 0.8, 0.6, 0.4, 0.2, and 0 Gz at the feet, for 30-s periods with 10-s transitions between levels. The same subjects underwent a corresponding supine LBNP protocol, up to 100 mmHg (in 20 mmHg increments) and back to zero pressure, which produced transmural pressure across blood vessels in the foot approximately equal to the HUT protocol. In general, application of all orthostatic stresses produced significant flow reductions in the lower body (p less than 0.05) and inconsistent changes in the neck. At low levels of each stress (0.4 Gz, 40 mmHg), LBNP generated the greatest relative reduction in flow in the lower body (-66.9+/-5.7%, thigh; -60.6 +/-5.7%, leg, mean +/- SE). HUT caused a less severe flow reduction than LBNP at the thigh and leg (-39.9 +/- 8.1% and -55.9+/-4.8%), while the effects induced by both forms of centrifugation were the least profound. Higher levels of each stress generally resulted in similar responses. These responses exhibit a consistent relationship to hypothesized changes in local microvascular transmural pressure, suggesting that myogenic and veno-arteriolar reflexes play a significant role in determining microvascular perfusion during orthostatic stress.

Breit, G. A.↗

Technology Investigations With the Tilt Rotor Aeroacoustic Model (TRAM)

This paper introduces the Tilt Rotor Aeroacoustic Model (TRAM) project. The TRAM project is a key infrastructure investment for NASA tiltrotor research. The TRAM project consists of the development and testing of two modular, hardware-compatible, test stands: an isolated rotor configuration and a fullspan model (dual rotors with a complete airframe representation). These two test stands are inclusively called the Tilt Rotor Aeroacoustic Model (TRAM). The baseline proprotors and airframe of the TRAM test stands are nominally 1/4-scale representative of the V-22 Osprey aircraft. The research objectives of the project, the TRAM hardware design features and capabilities, illustrative examples of the type and quality of data that can be acquired with the TRAM, and the current status of the overall project will be discussed in this paper.

Young, Larry A.↗

Context-specific adaptation of the gain of the oculomotor response to lateral translation using roll and pitch head tilts as contexts

Previous studies established that vestibular and oculomotor behaviors can have two adapted states (e.g., gain) simultaneously, and that a context cue (e.g., vertical eye position) can switch between the two states. The present study examined this phenomenon of context-specific adaptation for the oculomotor response to interaural translation (which we term "linear vestibulo-ocular reflex" or LVOR even though it may have extravestibular components). Subjects sat upright on a linear sled and were translated at 0.7 Hz and 0.3 gpeak acceleration while a visual-vestibular mismatch paradigm was used to adaptively increase (x2) or decrease (x0) the gain of the LVOR. In each experimental session, gain increase was asked for in one context, and gain decrease in another context. Testing in darkness with steps and sines before and after adaptation, in each context, assessed the extent to which the context itself could recall the gain state that was imposed in that context during adaptation. Two different contexts were used: head pitch (26 degrees forward and backward) and head roll (26 degrees or 45 degrees, right and left). Head roll tilt worked well as a context cue: with the head rolled to the right the LVOR could be made to have a higher gain than with the head rolled to the left. Head pitch tilt was less effective as a context cue. This suggests that the more closely related a context cue is to the response being adapted, the more effective it is.

Non-NASA Center↗

Effect of field size, head motion, and rotational velocity on roll vection and illusory self-tilt in a tumbling room

The effect of field size, velocity, and visual fixation upon the perception of self-body rotation and tilt was examined in a rotating furnished room. Subjects sat in a stationary chair in the furnished room which could be rotated about the body roll axis. For full-field conditions, complete 360 degrees body rotation (tumbling) was the most common sensation (felt by 80% of subjects). Constant tilt or partial tumbling (less than 360 degrees rotation) occurred more frequently with a small field of view (20 deg). The number of subjects who experienced complete tumbling increased with increases in field of view and room velocity (for velocities between 15 and 30 degrees s-1). The speed of perceived self-rotation relative to room rotation also increased with increasing field of view.

Non-NASA Center↗

Oculomotor control of primary eye position discriminates between translation and tilt

We have previously shown that fast phase axis orientation and primary eye position in rhesus monkeys are dynamically controlled by otolith signals during head rotations that involve a reorientation of the head relative to gravity. Because of the inherent ambiguity associated with primary otolith afferent coding of linear accelerations during head translation and tilts, a similar organization might also underlie the vestibulo-ocular reflex (VOR) during translation. The ability of the oculomotor system to correctly distinguish translational accelerations from gravity in the dynamic control of primary eye position has been investigated here by comparing the eye movements elicited by sinusoidal lateral and fore-aft oscillations (0.5 Hz +/- 40 cm, equivalent to +/- 0.4 g) with those during yaw rotations (180 degrees/s) about a vertically tilted axis (23.6 degrees). We found a significant modulation of primary eye position as a function of linear acceleration (gravity) during rotation but not during lateral and fore-aft translation. This modulation was enhanced during the initial phase of rotation when there was concomitant semicircular canal input. These findings suggest that control of primary eye position and fast phase axis orientation in the VOR are based on central vestibular mechanisms that discriminate between gravity and translational head acceleration.

NASA Discipline Neuroscience↗

Use of bed rest and head-down tilt to simulate spaceflight-induce immune system changes

Bed rest, both with and without head-down tilt, has been extensively used as an earth-bound analog to study physiologic effects mimicking those occurring in weightlessness during spaceflight. We have been able to show in six subjects that 4 weeks of head-down tilt bed rest induces a significant decrease in interleukin-2 secretion by PHA-stimulated T lymphocytes. Another study, lasting 113 days, with two subjects showed a decreased interleukin-2 receptor expression in PHA-stimulated peripheral blood mononuclear cells but a decreased interleukin-2 production in one subject only. Under the same conditions, interleukin-1 production was largely increased in both subjects. Several other immune parameters were also analyzed. Increased interleukin-1 production could contribute to bone mineral loss encountered during bed rest and decreased interleukin-2 secretion could play a role in the appearance of infectious diseases often observed during bed red.

NASA Discipline Neuroscience↗

Back pain during 6 degrees head-down tilt approximates that during actual microgravity

Astronauts often experience back pain during spaceflight. Retrospectively, Wing et al. (14) found that during spaceflight, 14 of 19 Shuttle crewmembers experienced back pain, which they described as dull (62%), localized to the lower back (50%), and with an intensity of 2 on a 5-point scale. Further, the spine lengthens 4-7 cm in microgravity. Our objective was to compare back pain and spinal lengthening (body height increase) during simulated microgravity (6 degrees head-down tilt, HDT) with the same parameters during actual microgravity. Eight male subjects completed a modified McGill pain questionnaire with intensity graded from zero (no pain) to five (intense and incapacitating pain) each day at 7:00 pm during 2 d pre-HDT control, 16 d HDT, and 1 d post-HDT recovery periods. Also, the subjects' heights were measured each day while supine (control and recovery) and during HDT. Back pain increased from zero (pre-tilt control period) to 2.3 +/- 0.4 at days 1 to 3 of HDT, and was categorized as dull and/or burning pain in subjects' lower backs. Only 2 subjects reported any pain after day 9 of HDT and during recovery. Heights increased 2.1 +/- 0.5 cm by day 3 of HDT and remained at that level until the end of the HDT period. Although spinal lengthening in space is greater than that during HDT, the HDT model approximates the level, type, distribution, and time course of back pain associated with actual microgravity. In the HDT model, pain subsides in intensity when spinal lengthening stops.(ABSTRACT TRUNCATED AT 250 WORDS).

Non-NASA Center↗