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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 235 records · Page 13
All sourcesNASA NTRSDOE OSTI
DOE OSTI2020

Quantile-dependent expressivity of plasma adiponectin concentrations may explain its sex-specific heritability, gene-environment interactions, and genotype-specific response to postprandial lipemia

“Quantile-dependent expressivity” occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g. adiponectin) is high or low relative to its distribution. We have previously shown that the heritability ( h 2 ) of adiposity, lipoproteins, postprandial lipemia, pulmonary function, and coffee and alcohol consumption are quantile-specific. Whether adiponectin heritability is quantile specific remains to be determined. Plasma adiponectin concentrations from 4,182 offspring-parent pairs and 1,662 sibships from the Framingham Heart Study were analyzed. Quantile-specific heritability from offspring-parent (β OP , h 2 = 2 β OP /(1 + r spouse )) and full-sib regression slopes ( β FS , h 2 = {(1 + 8r spouse β FS ) 0.05 -1}/(2r spouse )) were robustly estimated by quantile regression with nonparametric significance assigned from 1,000 bootstrap samples. Quantile-specific h 2 (± SE) increased with increasing percentiles of the offspring’s age- and sex-adjusted adiponectin distribution when estimated from β OP ( P trend = 2.2 × 10 -6 ): 0.30 ± 0.03 at the 10th, 0.33 ± 0.04 at the 25th, 0.43 ± 0.04 at the 50th, 0.55 ± 0.05 at the 75th, and 0.57 ± 0.08 at the 90th percentile, and when estimated from β FS (P trend = 7.6 × 10 -7 ): 0.42 ± 0.03 at the 10th, 0.44 ± 0.04 at the 25th, 0.56 ± 0.05 at the 50th, 0.73 ± 0.08 at the 75th, and 0.79 ± 0.11 at the 90th percentile. Consistent with quantile-dependent expressivity, adiponectin’s: (1) heritability was greater in women in accordance with their higher adiponection concentrations; (2) relationships to ADIPOQ polymorphisms were modified by adiposity in accordance with its adiponectin-lowering effect; (3) response to rosiglitazone was predicted by the 45T> G ADIPOQ polymorphism; (4) difference by ADIPOQ haplotypes increased linearly with increasing postprandial adiponectin concentrations. Adiponectin heritability is quantile dependent, which may explain sex-specific heritability, gene-environment and gene-drug interactions, and postprandial response by haplotypes.

Postprandial↗
DOE OSTI2018

Explaining Cold-Pulse Dynamics in Tokamak Plasmas Using Local Turbulent Transport Models

A long-standing enigma in plasma transport has been resolved by modeling of cold-pulse experiments conducted on the Alcator C-Mod tokamak. Controlled edge cooling of fusion plasmas triggers core electron heating on time scales faster than an energy confinement time, which has long been interpreted as strong evidence of nonlocal transport. This Letter shows that the steady-state profiles, the cold-pulse rise time, and disappearance at higher density as measured in these experiments are successfully captured by a recent local quasilinear turbulent transport model, demonstrating that the existence of nonlocal transport phenomena is not necessary for explaining the behavior and time scales of cold-pulse experiments in tokamak plasmas.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
NASA NTRS1970

Theory helps explain cancer growth

Theory explaining source of uncontrolled malignant growth, and suggestions for developing chemical measures against cancer

Source record↗
NASA NTRS1971

On explaining magnetic storm phenomena in the upper atmosphere and ionosphere.

Changes in ion and neutral compositions and in neutral, ion, and electron temperatures during the main phase of a magnetic storm are studied by solving a system of basic ionospheric and atmospheric differential equations. It is shown that a decrease in the atomic-to-molecular concentration ratio in the lower thermosphere may help explain several phenomena observed during a magnetic storm. These phenomena include decreases in the columnar electron content and increases in neutral temperature.

Stubbe, P.↗
NASA NTRS1985

A model for explaining some features of shuttle glow

A solid state model is proposed which hopefully removes some of the objections to excited atoms being sources for light emanating from surfaces. Glow features are discussed in terms of excited oxygen atoms impinged on the surface, although other species could be treated similarly. Band formation, excited lifetime shortening and glow color are discussed in terms of this model. The model's inability to explain glow emanating above surfaces indicates a necessity for other mechanisms to satisfy this requirements. Several ways of testing the model are described.

Peters, P. N.↗
NASA NTRS1986

The possible importance of synchrotron/inverse Compton losses to explain fast MM-wave and hard X-ray emission of a solar event

The solar burst of 21 May 1984 presented a number of unique features. The time profile consisted of seven major structures (seconds), with a turnover frequency or approx. 90 GHz, well correlated in time to hard X-ray emission. Each structure consisted of multiple fast pulses (.1 seconds), which were analyzed in detail. A proportionality between the repetition rate of the pulses and the burst fluxes at 90 GHz and or approx. 100 keV hard X-rays, and an inverse proportionality between repetition rates and hard X-rays power law indices have been found. A synchrotron/inverse Compton model has been applied to explain the emission of the fast burst structures, which appear to be possible for the first three or four structures.

Correia, E.↗
NASA NTRS1986

The possible importance of synchrotron/inverse Compton losses to explain fast mm-wave and hard X-ray emission of a solar event

The solar burst of 21 May 1984, presented a number of unique features. The time profile consisted of seven major structures (seconds), with a turnover frequency of greater than or approximately 90 GHz, well correlated in time to hard X-ray emission. Each structure consisted of multiple fast pulses (0.1 seconds), which were analyzed in detail. A proportionality between the repetition rate of the pulses and the burst fluxes at 90 GHz and greater than or approximately 100 keV hard X-rays, and an inverse proportionality between repetition rates and hard X-ray power law indices were found. A synchrotron/inverse Compton model was applied to explain the emission of the fast burst structures, which appear to be possible for the first three or four structures.

Correia, E.↗
NASA NTRS1989

Can the Exosat observations of DA white dwarfs be explained by layered atmospheric structures?

It is demonstrated that the Exosat broadband filter observations of DA white dwarfs, which have recently been interpreted with homogeneously mixed H/He atmospheres (Jordan et al, 1987; Paerels and Heise, 1989), can be explained with stratified theoretical models. In these models a very thin H layer is floating on top of the underlying He. The transition zone is determined by diffusive equilibrium. The resulting total hydrogen-layer masses are in the range (3-500) x 10 to the -16th solar mass. Several arguments are discussed that could lead to a decision about the correct interpretation, but a final answer is not possible.

Koester, D.↗
NASA NTRS1991

Explanations in knowledge systems - Design for Explainable Expert Systems

The Explainable Expert Systems framework (EES), in which the focus is on capturing those design aspects that are important for producing good explanations, including justifications of the system's actions, explications of general problem-solving strategies, and descriptions of the system's terminology, is discussed. EES was developed as part of the Strategic Computing Initiative of DARPA. Both the general principles from which the system was derived and how the system was derived from those principles can be represented in EES. The Program Enhancement Advisor, which is the main prototype on which the explanation work has been developed and tested, is presented. PEA is an advice system that helps users improve their Common Lisp programs by recommending transformations that enhance the user's code. How EES produces better explanations is shown.

Swartout, William↗
NASA NTRS1992

An investigation of mechanisms other than lightning to explain certain wideband plasma wave bursts detected in the Venusian nightside ionosphere

Several related topics are briefly discussed. Reviewed here is work on an investigation of plasma wave phenomena associated with the question of lightning on Venus. The work supported the contention that lightning is at least a candidate explanation for many of the 100 Hz-only Pioneer Venus orbital electric field detector (OEFD) signals. A review of the work on the investigation of mechanisms other than lightning to explain certain wideband plasma wave bursts detected in the Venusian nightside ionosphere is given. A summary is given of our analysis of data from 23 OEFD observing periods as well as a discussion of the properties of specifically multifrequency events. Our opportunity to work on this topic was not sufficient to draw any firm conclusions about the origins of the multifrequency bursts, but we call attention to what we consider to be several candidate sources. Also discussed are case studies to test for evidence of whistler mode propagation from subionospheric sources, results of a search for dispersive effects in the OEFD data, the results for a search for simultaneous 100 Hz and 730 Hz observations at altitudes below 150 km, changes with altitude in dispersive broadening effects in the time signatures of 100 Hz bursts, and a survey of activity at altitudes above 1000 km.

Carpenter, D. L.↗
NASA NTRS1995

Explaining the Accumulation of Intercontinental Biomass Burning Pollution: High Versus Low Processes, Africa Versus South America, Cooking Versus Mixing

The intercontinental buildup of tropospheric ozone, carbon monoxide, and other pollutants over the South Atlantic has been attributed to biomass burning over distant continents. We address several of the large questions regarding the nature and budget of this buildup have remained: What is the role of turning In South America or various portions of Africa in this accumulation? What are the relative roles of shallow and deep convection for emplacing various compounds in the free troposphere? Can we understand the ozone budget? We report the first simulations of a three-dimensional pollutant transport model, (GRACES) transport which is driven by fully reconstructed meteorology for the TRACE-A/SAFARI period of 1992. Greater detail is provided by a two-dimensional, detailed-chemistry model of more restricted regions of Africa. We find a predominant role for African emissions affecting the Atlantic during this period. Boundary-layer venting via PBL convection tends to build the observed carbon monoxide column over the ocean, while deep cumulonimbus processes tend to explain rather more of the ozone column.

Chatfield, Robert B.↗
NASA NTRS1998

Explaining Synthesized Software

Motivated by NASA's need for high-assurance software, NASA Ames' Amphion project has developed a generic program generation system based on deductive synthesis. Amphion has a number of advantages, such as the ability to develop a new synthesis system simply by writing a declarative domain theory. However, as a practical matter, the validation of the domain theory for such a system is problematic because the link between generated programs and the domain theory is complex. As a result, when generated programs do not behave as expected, it is difficult to isolate the cause, whether it be an incorrect problem specification or an error in the domain theory. This paper describes a tool we are developing that provides formal traceability between specifications and generated code for deductive synthesis systems. It is based on extensive instrumentation of the refutation-based theorem prover used to synthesize programs. It takes augmented proof structures and abstracts them to provide explanations of the relation between a specification, a domain theory, and synthesized code. In generating these explanations, the tool exploits the structure of Amphion domain theories, so the end user is not confronted with the intricacies of raw proof traces. This tool is crucial for the validation of domain theories as well as being important in everyday use of the code synthesis system. It plays an important role in validation because when generated programs exhibit incorrect behavior, it provides the links that can be traced to identify errors in specifications or domain theory. It plays an important role in the everyday use of the synthesis system by explaining to users what parts of a specification or of the domain theory contribute to what pieces of a generated program. Comments are inserted into the synthesized code that document these explanations.

VanBaalen, Jeffrey↗
NASA NTRS2002

Element-Element Correlations Among Martian Meteorite Bulk Compositions: Peculiarities Explained(?) by Mixing, with Implications for the Composition of Mars

Most estimates of the chemical corn position of Mars' mantle and core derive from elementelement correlations bulk analyses of Martian meteorites [I-31. To use the correlations in this manner assumes implicitly that they reflect mineraVmelt fractionations (e.g., partial melting, fractional crystallization, accumulation) among a cogenetic suite of igneous rocks. However, similar correlations can zppear from mixing of chemical components, and need not imply that the components were cogenetic nor that they had an igneous origin. Several aspects of the elemental and isotopic chem istries of the Martian meteorites can be explained by mixing of geochemical components (mantle or crustal), e.g. [5,6]. Thus, it is worth asking whether mixing rektions might be seen in bulk chemical data, and (if so) whether the mixing components can be used to infer average planet or mantle compositions.

Treiman, A. H.↗
NASA NTRS2004

Explaining the Mid-Latitude Ice Deposits with a General Circulation Model

Though plausible explanations for the high latitude subsurface hydrogen features on Mars have been put forth, there still lacks a consensus on the nature of the low-latitude hydrogen features found in Arabia Terra and Daedalia Planum. While equivalent water mass fractions in these regions are low enough to potentially be explained by the presence of hydrated minerals, it still remains possible that such features are the remnants of ice deposits left from a previous period of high obliquity and which is now thermally unstable and subliming. In order to explore the thermal stability of putative ice deposits at low latitudes, we use the Geophysical Fluid Dynamics Laboratory (GFDL) Mars GCM with a newly integrated subsurface scheme to trace the deposition and sublimation rates of water ice, adsorbate and vapor across the planet at varying obliquities. In addition, these results help resolve the question of the dominant means of ice emplacement in the near surface, whether such ice is the result of buried surface deposits, or in situ emplaced ice due to vapor diffusion.

Mischna, M. A.↗
NASA NTRS2008

Explaining Warm Coronal Loops

One of the great mysteries of coronal physics that has come to light in the last few years is the discovery that warn (- 1 INK) coronal loops are much denser than expected for quasi-static equilibrium. Both the excess densities and relatively long lifetimes of the loops can be explained with bundles of unresolved strands that are heated impulsively to very high temperatures. Since neighboring strands are at different stages of cooling, the composite loop bundle is multi-thermal, with the distribution of temperatures depending on the details of the "nanoflare storm." Emission hotter than 2 MK is predicted, but it is not clear that such emission is always observed. We consider two possible explanations for the existence of over-dense warm loops without corresponding hot emission: (1) loops are bundles of nanoflare heated strands, but a significant fraction of the nanoflare energy takes the form of a nonthermal electron beam rather then direct plasma heating; (2) loops are bundles of strands that undergo thermal nonequilibrium that results when steady heating is sufficiently concentrated near the footpoints. We present numerical hydro simulations of both of these possibilities and explore the observational consequences, including the production of hard X-ray emission and absorption by cool material in the corona.

Klimchuk, James A.↗
NASA NTRS2010

AIRS Products Confirm and Explain Recent Negative Trends of OLR as Observed by CERES

Anomalies and trends of OLR serve as important indicators of climate change. Several satellite based instruments currently provide information related to OLR. CERES, on board the EOS Aqua and Terra satellites, contains broad band radiometers that measure total flux and short-wave flux, from which OLR is determined. AIRS is a high spectral resolution IR sounder on EOS Aqua that measures IR radiances covering most of the spectral interval 650/cm to 2670/cm. These observations enable the determination of detailed information about atmospheric temperature, moisture, and ozone profiles, as well as surface skin temperatures and cloud parameters. The AIRS OLR product is the total flux over the spectral interval 2/cm to 2750/cm computed for the surface and atmospheric state determined from AIRS observations. We compared spatial anomalies and trends of OLR, over the seven year period September 2002 through August 2009, as observed by CERES and computed using Version-5 AIRS products. These two sets of OLR anomalies and trends, obtained in very different ways, agree with each other almost perfectly in essentially every detail. This important finding shows that a very stable high spectral infra-red sounder such as AIRS corroborates the anomalies and trends of OLR obtained from CERES. More significantly, anomalies and trends of the individual geophysical parameters derived from AIRS explain the detailed causes of the anomalies and trends of CERES OLR. Both sets of results show that global mean OLR has been decreasing at a rate of 0.12 W/sq m/yr over the seven year time period under study. Both also confirm that the primary cause of this is due to changes in the tropics, in which OLR has been decreasing at a rate of 0.27 W/sq m/yr. AIRS products show that the decrease of tropical OLR is a result of increasing tropical atmospheric water vapor and cloud cover over that time period studied, which in turn is responding to a very strong La Nina; a event starting in late 2007. Equatorial ocean temperatures between 160 E and 120 W cooled considerably during this time period, with corresponding local decreases in mid-tropospheric humidity and cloud cover, resulting in increases in local OLR. This was more than compensated by substantial increases in water vapor and cloud cover elsewhere in the tropics, resulting in a net decrease in tropical OLR. The AIRS Version-5 products currently extend through December 2009. An El Nino event began in late 2009. AIRS products show that tropical OLR began to increase at that time, and there was a corresponding reversal of sign of tropical cloud and water vapor anomalies.

Susskind, Joel↗