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NASA NTRS2021

Hypersonic Boundary-Layer Transition on Blunted Cones at Angle of Attack

Experimental studies of cones at several high-speed facilities have demonstrated that, for small nosetip bluntness, transition onset over a circular cone moves upstream along the leeward side and downstream along the windward side, but this trend may be reversed at large bluntness values, where transition onset moves downstream along the leeward side and upstream along the windward side. A theoretical and numerical investigation is performed to characterize the effects of nose bluntness on disturbance amplification over the circular cone for several angles of attack, with the goal of understanding the potential physical mechanisms behind the experimental observations. The three-dimensional laminar basic states over a 1.5 m long, 7-degree half-angle cone with 9.525 mm nosetip radius are computed for selected angles of attack values and freestream conditions that are selected to match the Mach 10 experiments conducted within the Hypervelocity Wind Tunnel 9 at the Arnold Engineering Development Complex (AEDC). The solutions at a freestream unit Reynolds number of 17.1 million per meter are used to perform detailed instability analyses for angles of attack equal to 0, 1, 3, and 5 degrees. Results indicate that the linear amplification of stationary crossflow waves along inflection lines may begin to influence transition along the acreage of the cone for angles of attack equal to or larger than 5 degrees. The measured trend in transition front with respect to increasing angle of attack is found to be consistent with the predicted increase in the amplification factors for Mack mode disturbances along the streamline trajectories. The increase in Mack mode amplification along the windward ray for higher angles of attack is shown to be the result of a progressively earlier entropy-layer swallowing. Computations also indicate that the transition amplification factor along the windward ray is not constant and increases with the angle of attack and that the transition #-factors along the leeward ray are rather small. The nonmodal analysis for zero degrees angle of attack shows that entropy-layer disturbances with appreciably strong energy growth can coexist with Mack mode instabilities at the measured transition location.

Boundary Layer Transition↗

NASA NTRS2023

Effect of Scattering Angle on DSCOVR/EPIC Observations

The Earth Polychromatic Imaging Camera (EPIC) on the Deep Space Climate Observatory (DSCOVR) routinely captures reflected radiation from the whole sunlit side of the Earth in the near backward direction to monitor the changing planet. The instrument had routinely operated until 27 June 2019, when the spacecraft was placed in an extended safe hold due to degradation of an inertial navigation unit. DSCOVR returned to full operations on 2 March 2020. Since then, the range of scattering angles between the incident sunlight and sensor direction has been larger than before and the largest scattering angle reaches ∼178°, only 2° from perfect backscattering, proving a unique opportunity to study the top-of-atmosphere (TOA) reflectance under such extreme conditions. In the paper, we compare EPIC global spectral reflectances in 2021–2016. We found that there are four occasions when the scattering angle reaches about 178° and associated with them enhanced global daily average spectral reflectances in 2021. The scattering angle related reflectance enhancements are not found in 2016 data when the maximum scattering angle is about 174.5°. CERES data do not show such occasions in global daily reflected shortwave flux. As a result, those enhanced reflectance occasions are primarily due to the change in scattering angle. The enhancement due to changes in scattering angle depends strongly on wavelength, primarily because of wavelength dependence of cloud scattering phase function. Radiative transfer calculations show that the change in scattering angles has the largest impact on reflectance in the red and NIR channels at 680 nm and 780 nm and the smallest influence on reflectance in the UV channel at 388 nm, consistent with EPIC observations. The change of global average cloud amount also plays an important role in the reflectance enhancement. The influence of the cloud effect depends on whether the change is in phase or not with the change of scattering angle.

DSCOVR EPIC↗

DOE OSTI2017

Contact angles from Young’s equation in molecular dynamics simulations

In this work, we propose a method to calculate the equilibrium contact angle of heterogeneous 3-phase solid/fluid/fluid systems using molecular dynamics simulations. The proposed method, which combines the phantom-wall method [F. Leroy and F. Müller-Plathe, J. Chem. Phys. 133, 044110 (2010)] and Bennett’s acceptance ratio approach [C. H. Bennett, J. Comput. Phys. 22, 245 (1976)], is able to calculate the solid/fluid surface tension relative to the solid surface energy. The calculated relative surface tensions can then be used in Young’s equation to estimate the equilibrium contact angle. A fluid droplet is not needed for the proposed method, in contrast to the situation for direct simulations of contact angles. In addition, while prior free-energy based methods for contact angles mainly focused on the wetting of fluids in coexistence with their vapor on solid surfaces, the proposed approach was designed to study the contact angles of fluid mixtures on solid surfaces above the fluid saturation pressures. Using the proposed approach, the contact angles of binary Lennard-Jones fluid mixtures on a non-polar solid substrate were calculated at various interaction parameters and the contact angle of water in equilibrium with CO 2 on a hydrophilic polar silica surface was obtained. For both non-polar and polar systems, the calculated contact angles from the proposed method were in agreement with those obtained from the geometry of a cylindrical droplet. The computational cost of the proposed method was found to be comparable to that of simulations that use fluid droplets, but the new method provides a way to calculate the contact angle directly from Young’s equation without ambiguity.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2014

A new method to estimate local pitch angles in spiral galaxies: Application to spiral arms and feathers in M81 and M51

We examine 8 μm IRAC images of the grand design two-arm spiral galaxies M81 and M51 using a new method whereby pitch angles are locally determined as a function of scale and position, in contrast to traditional Fourier transform spectral analyses which fit to average pitch angles for whole galaxies. The new analysis is based on a correlation between pieces of a galaxy in circular windows of (lnR,θ) space and logarithmic spirals with various pitch angles. The diameter of the windows is varied to study different scales. The result is a best-fit pitch angle to the spiral structure as a function of position and scale, or a distribution function of pitch angles as a function of scale for a given galactic region or area. We apply the method to determine the distribution of pitch angles in the arm and interarm regions of these two galaxies. In the arms, the method reproduces the known pitch angles for the main spirals on a large scale, but also shows higher pitch angles on smaller scales resulting from dust feathers. For the interarms, there is a broad distribution of pitch angles representing the continuation and evolution of the spiral arm feathers as the flow moves into the interarm regions. Our method shows a multiplicity of spiral structures on different scales, as expected from gas flow processes in a gravitating, turbulent and shearing interstellar medium. We also present results for M81 using classical 1D and 2D Fourier transforms, together with a new correlation method, which shows good agreement with conventional 2D Fourier transforms.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2022

Polarization angle requirements for CMB B-mode experiments. Application to the LiteBIRD satellite

A methodology to provide the polarization angle requirements for different sets of detectors, at a given frequency of a CMB polarization experiment, is presented. The uncertainties in the polarization angle of each detector set are related to a given bias on the tensor-to-scalar ratio r parameter. The approach is grounded in using a linear combination of the detector sets to obtain the CMB polarization signal. In addition, assuming that the uncertainties on the polarization angle are in the small angle limit (lower than a few degrees), it is possible to derive analytic expressions to establish the requirements. The methodology also accounts for possible correlations among detectors, that may originate from the optics, wafers, etc. The approach is applied to the LiteBIRD space mission. We show that, for the most restrictive case (i.e., full correlation of the polarization angle systematics among detector sets), the requirements on the polarization angle uncertainties are of around 1 arcmin at the most sensitive frequency bands (i.e., ≈ 150 GHz) and of few tens of arcmin at the lowest (i.e., ≈ 40 GHz) and highest (i.e., ≈ 400 GHz) observational bands. Conversely, for the least restrictive case (i.e., no correlation of the polarization angle systematics among detector sets), the requirements are ≈ 5 times less restrictive than for the previous scenario. At the global and the telescope levels, polarization angle knowledge of a few arcmins is sufficient for correlated global systematic errors and can be relaxed by a factor of two for fully uncorrelated errors in detector polarization angle. The reported uncertainty levels are needed in order to have the bias on r due to systematics below the limit established by the LiteBIRD collaboration.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2015

PHASE ANGLE EFFECTS ON 3 μm ABSORPTION BAND ON CERES: IMPLICATIONS FOR DAWN MISSION

Phase angle-induced spectral effects are important to characterize since they affect spectral band parameters such as band depth and band center, and therefore skew mineralogical interpretations of planetary bodies via reflectance spectroscopy. Dwarf planet (1) Ceres is the next target of NASA’s Dawn mission, which is expected to arrive in 2015 March. The visible and near-infrared mapping spectrometer (VIR) on board Dawn has the spatial and spectral range to characterize the surface between 0.25–5.0 μm. Ceres has an absorption feature at 3.0 μm due to hydroxyl- and/or water-bearing minerals. We analyzed phase angle-induced spectral effects on the 3 μm absorption band on Ceres using spectra measured with the long-wavelength cross-dispersed (LXD: 1.9–4.2 μm) mode of the SpeX spectrograph/imager at the NASA Infrared Telescope Facility. Ceres LXD spectra were measured at different phase angles ranging from 0.°7 to 22°. We found that the band center slightly increases from 3.06 μm at lower phase angles (0.°7 and 6°) to 3.07 μm at higher phase angles (11° and 22°), the band depth decreases by ∼20% from lower phase angles to higher phase angles, and the band area decreases by ∼25% from lower phase angles to higher phase angles. Our results will have implications for constraining the abundance of OH on the surface of Ceres from VIR spectral data, which will be acquired by Dawn starting spring 2015.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2013

A technique for estimating 4D-CBCT using prior knowledge and limited-angle projections

Purpose: To develop a technique to estimate onboard 4D-CBCT using prior information and limited-angle projections for potential 4D target verification of lung radiotherapy.Methods: Each phase of onboard 4D-CBCT is considered as a deformation from one selected phase (prior volume) of the planning 4D-CT. The deformation field maps (DFMs) are solved using a motion modeling and free-form deformation (MM-FD) technique. In the MM-FD technique, the DFMs are estimated using a motion model which is extracted from planning 4D-CT based on principal component analysis (PCA). The motion model parameters are optimized by matching the digitally reconstructed radiographs of the deformed volumes to the limited-angle onboard projections (data fidelity constraint). Afterward, the estimated DFMs are fine-tuned using a FD model based on data fidelity constraint and deformation energy minimization. The 4D digital extended-cardiac-torso phantom was used to evaluate the MM-FD technique. A lung patient with a 30 mm diameter lesion was simulated with various anatomical and respirational changes from planning 4D-CT to onboard volume, including changes of respiration amplitude, lesion size and lesion average-position, and phase shift between lesion and body respiratory cycle. The lesions were contoured in both the estimated and “ground-truth” onboard 4D-CBCT for comparison. 3D volume percentage-difference (VPD) and center-of-mass shift (COMS) were calculated to evaluate the estimation accuracy of three techniques: MM-FD, MM-only, and FD-only. Different onboard projection acquisition scenarios and projection noise levels were simulated to investigate their effects on the estimation accuracy.Results: For all simulated patient and projection acquisition scenarios, the mean VPD (±S.D.)/COMS (±S.D.) between lesions in prior images and “ground-truth” onboard images were 136.11% (±42.76%)/15.5 mm (±3.9 mm). Using orthogonal-view 15°-each scan angle, the mean VPD/COMS between the lesion in estimated and “ground-truth” onboard images for MM-only, FD-only, and MM-FD techniques were 60.10% (±27.17%)/4.9 mm (±3.0 mm), 96.07% (±31.48%)/12.1 mm (±3.9 mm) and 11.45% (±9.37%)/1.3 mm (±1.3 mm), respectively. For orthogonal-view 30°-each scan angle, the corresponding results were 59.16% (±26.66%)/4.9 mm (±3.0 mm), 75.98% (±27.21%)/9.9 mm (±4.0 mm), and 5.22% (±2.12%)/0.5 mm (±0.4 mm). For single-view scan angles of 3°, 30°, and 60°, the results for MM-FD technique were 32.77% (±17.87%)/3.2 mm (±2.2 mm), 24.57% (±18.18%)/2.9 mm (±2.0 mm), and 10.48% (±9.50%)/1.1 mm (±1.3 mm), respectively. For projection angular-sampling-intervals of 0.6°, 1.2°, and 2.5° with the orthogonal-view 30°-each scan angle, the MM-FD technique generated similar VPD (maximum deviation 2.91%) and COMS (maximum deviation 0.6 mm), while sparser sampling yielded larger VPD/COMS. With equal number of projections, the estimation results using scattered 360° scan angle were slightly better than those using orthogonal-view 30°-each scan angle. The estimation accuracy of MM-FD technique declined as noise level increased.Conclusions: The MM-FD technique substantially improves the estimation accuracy for onboard 4D-CBCT using prior planning 4D-CT and limited-angle projections, compared to the MM-only and FD-only techniques. It can potentially be used for the inter/intrafractional 4D-localization verification.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

DOE OSTI2016

TH-CD-209-02: Beam Angle Optimization Incorporating Anatomical Heterogeneities for Pencil Beam Scanning Charged-Particle Therapy

Purpose: In charged particle therapy with pencil beam scanning (PBS), localization of the dose in the Bragg peak makes dose distributions sensitive to lateral tissue heterogeneities. Sensitivity of a PBS plan to lateral tissue heterogeneity can be reduced by selecting suitable beam angles. The purpose of this study is to establish a fast and accurate method of beam angle selection for PBS. Methods: The lateral tissue heterogeneity surrounding the path of respective pencil beams at a given angle was quantified with the heterogeneity number using effective density data of patients. To shorten the computation time, one dimensional dose calculation and optimization were conducted along the central axis of pencil beams originating from the scanning magnets. Calculation was performed for all fields with possible gantry and couch angles. The angles leading the minimum mean heterogeneity number was selected as the optimal beam angle. Three head and neck (H&N) cancer patients were used to evaluate our method. Dose distributions and their robustness to range and set up errors were evaluated for all tested angles, and their relation to their heterogeneity numbers were investigated. Results: Variety of heterogeneity number was clearly shown due to air cavities and bony structures in the patients. The mean value of heterogeneity number in all possible fields varied between 1.2 and 10.6 mm. By selecting a field with a lower mean value of heterogeneity number, target dose coverage and robustness of the fields were improved. Conclusion: We developed a computational method to determine a beam angle that leads good target coverage and robustness to setup errors. The developed stand-alone computation program is simple, fast, accurate and applicable for beam angle selection in PBS therapy.

60 APPLIED LIFE SCIENCES↗

DOE OSTI2022

Fast yaw optimization for wind plant wake steering using Boolean yaw angles

Abstract. In wind plants, turbines can be yawed into the wind to steer their wakes away from downstream turbines and achieve an overall increase in plant power. Mathematical optimization is typically used to determine the best yaw angles at which to operate the turbines in a plant. In this paper, we present a new heuristic to rapidly determine the yaw angles in a wind plant. In this method, we define the turbine yaw angles as Boolean – either yawed at a predefined angle or nonyawed – as opposed to the typical methods of defining yaw angles as continuous or with fine discretizations. We then optimize which turbines should be yawed with an algorithm that sweeps through the turbines from the most upstream to the most downstream. We demonstrate that our new Boolean optimization method can find turbine yaw angles that perform well compared to a traditionally used gradient-based optimizer for which the yaw angles are defined as continuous. There is less than 0.6 % difference in the optimized power between the two optimization methods for randomly placed turbine layouts and less than a 0.6 % difference in the optimal annual energy production between the two optimization methods for a real wind farm. Additionally, we show that our new method is much more computationally efficient than the traditional method. For plants with nonzero optimal yaw angles, our new method is generally able to solve for the turbine yaw angles 50–150 times faster, and in some extreme cases up to 500 times faster, than the traditional method.

17 WIND ENERGY↗

NASA NTRS1985

Sun-view angle effects on reflectance factors of corn canopies

The effects of sun and view angles on reflectance factors of corn (Zea mays L.) canopies ranging from the six leaf stage to harvest maturity were studied on the Purdue University Agronomy Farm by a multiband radiometer. The two methods of acquiring spectral data, the truck system and the tower systrem, are described. The analysis of the spectral data is presented in three parts: solar angle effects on reflectance factors viewed at nadir; solar angle effects on reflectance factors viewed at a fixed sun angle; and both sun and view angles effect on reflectance factors. The analysis revealed that for nadir-viewed reflectance factors there is a strong solar angle dependence in all spectral bands for canopies with low leaf area index. Reflectance factors observed from the sun angle at different view azimuth angles showed that the position of the sensor relative to the sun is important in determining angular reflectance characteristics. For both sun and view angles, reflectance factors are maximized when the sensor view direction is towards the sun.

Ranson, K. J.↗

NASA NTRS1987

High angle of attack hypersonic aerodynamics

A new aerodynamics force model is presented which is based on modified Newtonian theory and empirical correlations. The algebraic model was developed for complete vehicles from take off to orbital speeds and for large angles of attack. Predictions are compared to results for a wind tunnel model at a Mach number of 20, and the full scale Shuttle Orbiter for Mach numbers from 0.25 to 20 for angles of attack from 0 to 50 deg. The maximum shuttle orbiter lift/drag at Mach 10 and 20 is 1.85 at 20-deg angle-of-attack. Aerodynamic force predictions are made for a transatmospheric vehicle, which is a derivative of the Shuttle Orbiter, for Mach numbers from 4 to 27 at angles of attack from 5 to 40 deg. Predicted aerodynamic force data indicate that lift/drag ratios of 5.2 at Mach number 10 and 3.6 at Mach number 26 are obtainable. Changes in force coefficients with changes in: nose angle, sweep angle, and (volume exp 2/3)/planform area are quantified for Mach numbers of 10 and 26. Lift/drag ratios increase with decreasing nose angle and (volume exp 2/3)/planform area and increasing wing sweep angle. Lift/drag ratios are independent of these variables for angles of attack in excess of 20 deg at Mach 10 and 30 deg at Mach 26.

Harloff, Gary J.↗

NASA NTRS1992

Direction angle sensitivity of agricultural field backscatter with Airsar data

The direction angle sensitivity of agricultural field backscatter is studied. The direction angle is defined as the angle between the incident plane and the perpendicular to the row direction. Maximum backscatter power from an angricultural field is expected to occur when the furrow induced slopes are oriented towards the radar, i.e., for a 0 deg direction angle. This effect is known as the cardinal effect. Because of the way the looks are formed in the NASA/JPL airborne synthetic aperture radar (AIRSAR) processor, each look corresponds to a slightly different squint angle. This provides a unique data set to analyze the cardinal effect, as it allows simultaneous observations of the backscatter of a field for sixteen different direction angles. The backscatter variations of the agricultural fields with direction angle at P-, L-, and C-bands is described. The observed variations in backscatter are compared with model predictions. The model predicts that the maximum backscatter occurs for a 0 deg direction angle, but underestimates the backscatter variations with direction angle by more than 10 dB.

Dubois, Pascale C.↗

NASA NTRS1959

Performance of Typical Rear-Stage Axial-Flow Compressor Rotor Blade Row at Three Different Blade Setting Angles

A comparison of the performance of a single-stage rotor run at three different blade setting angles is presented. The rotor was of a design typical for a last stage of a multistage compressor. At each setting angle, the rotor blade row was operated from 53 to 100 percent of equivalent maximum speed (850 ft/sec tip speed) at constant inlet pressure. Hot-wire anemometry was used to observe rotating-stall and surge patterns in time unsteady flow. Results indicated that an increase in peak pressure ratio and an increase in maximum equivalent weight flow were obtained at each speed investigated when the blade setting angle was decreased. An increase in peak efficiency was achieved with decrease in blade setting angle for part of the range of speeds investigated. However, the peak efficiencies for the three blade setting angles were approximately the same at the maximum speed investigated. The flow ranges for all three configurations were about the same at minimum speed and decreased at almost the same rate when the rotative speed was increased through part of the range of speeds investigated. At maximum speed, the flow range for the smallest setting angle was considerably less than the flow range for the other two configurations. A decrease in efficiency and flow range for the smallest blade setting angle at maximum speed can be attributed primarily to a Mach number effect. In addition, because of the difference in projected axial chord lengths at the casing wall, some effect on performance could be expected from the change in three-dimensional flow occurring at the tip. Rotating-stall characteristics for the two smaller blade setting angles were essentially the same. Only surge could be detected for the largest blade setting angle in the unstable-flow region of operation.

Kussoy, Marvin I.↗

NASA NTRS2003

Touch and gravitropic set-point angle interact to modulate gravitropic growth in roots

Plant roots must sense and respond to a variety of environmental stimuli as they grow through the soil. Touch and gravity represent two of the mechanical signals that roots must integrate to elicit the appropriate root growth patterns and root system architecture. Obstacles such as rocks will impede the general downwardly directed gravitropic growth of the root system and so these soil features must be sensed and this information processed for an appropriate alteration in gravitropic growth to allow the root to avoid the obstruction. We show that primary and lateral roots of Arabidopsis do appear to sense and respond to mechanical barriers placed in their path of growth in a qualitatively similar fashion. Both types of roots exhibited a differential growth response upon contacting the obstacle that directed the main axis of elongation parallel to the barrier. This growth habit was maintained until the obstacle was circumvented, at which point normal gravitropic growth was resumed. Thus, the gravitational set-point angle of the primary and lateral roots prior to encountering the barrier were 95 degrees and 136 degrees respectively and after growing off the end of the obstacle identical set-point angles were reinstated. However, whilst tracking across the barrier, quantitative differences in response were observed between these two classes of roots. The root tip of the primary root maintained an angle of 136 degrees to the horizontal as it traversed the barrier whereas the lateral roots adopted an angle of 154 degrees. Thus, this root tip angle appeared dependent on the gravitropic set-point angle of the root type with the difference in tracking angle quantitatively reflecting differences in initial set-point angle. Concave and convex barriers were also used to analyze the response of the root to tracking along a continuously varying surface. The roots maintained the a fairly fixed angle to gravity on the curved surface implying a constant resetting of this tip angle/tracking response as the curve of the surface changed. We propose that the interaction of touch and gravity sensing/response systems combine to strictly control the tropic growth of the root. Such signal integration is likely a critical part of growth control in the stimulus-rich environment of the soil. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

NASA Discipline Plant Biology↗

NASA NTRS2021

Hypersonic Boundary-Layer Transition on Blunted Cones at Angle of Attack

boundary layer transition↗

DOE OSTI2016

The Solid Angle for a Spherical Surface Source and a Detector with an Arbitrary Aperture: An Elegant Proof

It has previously been proven that the solid angle (or geometry factor, also called the geometrical efficiency) for a spherically symmetric outward-directed surface source with an arbitrary radius and polar angle distribution and an arbitrary detector aperture is equal to the solid angle for an isotropic point source located at the center of the spherical surface source and the same detector aperture. The solid angle for a source-detector system is the fraction of source particles that enter the detector aperture and so it is not purely geometric-the angular distribution of the source is a factor. The previous proof relied on an analytic transport-theory (streaming only) calculation of the solid angle Ω for a spherically symmetric surface source and a point detector. In this paper, a new, more elegant proof is given. Since the net current across any portion of a plane that intersects the center of a spherical surface source is zero, the solid angle for a spherical surface source with any polar angle distribution and a uniform azimuthal angle distribution and any detector aperture is equal to the solid angle for an isotropic point source and the same detector. This insight obviates the calculus and trigonometry involved in the previous proof. (author)

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

DOE OSTI2022

Multiscale water drop contact angles at selected silica surfaces

In this paper, multiscale advancing contact angles for glycerol/water drops at silica surfaces are reported for millidrops, submicron-drops, and nanodrops. Selected silica surfaces were muscovite, silicon, and talc. The contact angles for millidrops (1–2 mm) were determined by the traditional sessile drop technique. For submicron-drops (0.1–1.0 μm), a hollow tip Atomic Force Microscope (AFM) procedure was used. The contact angles for nanodrops (~7 nm) were examined from Molecular Dynamics (MD) simulation. The results were compared to evaluate the effect of drop size on the contact angle. In the case of the hydrophobic talc surface, the 75° advancing contact angle did not vary significantly with drop size. For the hydrophilic muscovite surface, the water drop wet the surface and an advancing contact angle of about 10° was found for the millidrops and submicron-drops. However, for the MD simulated nanodrops, attachment and spreading of the ~7 nm drop created a 2D film of molecular dimensions, the contact angle of which was difficult to define and varied from 0° to 17°. Perhaps of equal interest from the MD simulation results was that the spreading of the glycerol/water nanodrop at the muscovite surface resulted in crystallographic directional transport of water molecules to the extremities of the 2D film. Such separation and segregation left the center of the film with an increased concentration of glycerol. Based on these results, the line tension, which has been found in other investigations to account for contact angle decrease with a decrease in drop size, does not seem to be a significant factor in this study.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2017

Individualized Selection of Beam Angles and Treatment Isocenter in Tangential Breast Intensity Modulated Radiation Therapy

Purpose and Objective: Propose a novel method for individualized selection of beam angles and treatment isocenter in tangential breast intensity modulated radiation therapy (IMRT). Methods and Materials: For each patient, beam and isocenter selection starts with the fully automatic generation of a large database of IMRT plans (up to 847 in this study); each of these plans belongs to a unique combination of isocenter position, lateral beam angle, and medial beam angle. The imposed hard planning constraint on patient maximum dose may result in plans with unacceptable target dose delivery. Such plans are excluded from further analyses. Owing to differences in beam setup, database plans differ in mean doses to organs at risk (OARs). These mean doses are used to construct 2-dimensional graphs, showing relationships between: (1) contralateral breast dose and ipsilateral lung dose; and (2) contralateral breast dose and heart dose (analyzed only for left-sided). The graphs can be used for selection of the isocenter and beam angles with the optimal, patient-specific tradeoffs between the mean OAR doses. For 30 previously treated patients (15 left-sided and 15 right-sided tumors), graphs were generated considering only the clinically applied isocenter with 121 tangential beam angle pairs. For 20 of the 30 patients, 6 alternative isocenters were also investigated. Results: Computation time for automatic generation of 121 IMRT plans took on average 30 minutes. The generated graphs demonstrated large variations in tradeoffs between conflicting OAR objectives, depending on beam angles and patient anatomy. For patients with isocenter optimization, 847 IMRT plans were considered. Adding isocenter position optimization next to beam angle optimization had a small impact on the final plan quality. Conclusion: A method is proposed for individualized selection of beam angles in tangential breast IMRT. This may be especially important for patients with cardiac risk factors or an enhanced risk for the development of contralateral breast cancer.

62 RADIOLOGY AND NUCLEAR MEDICINE↗