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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 235 records · Page 13
All sourcesNASA NTRSDOE OSTI
NASA NTRS2016

Pharmaceuticals Exposed to the Space Environment: Problems and Prospects

The NASA Human Research Program (HRP) Health Countermeasures Element maintains ongoing efforts to inform detailed risks, gaps, and further questions associated with the use of pharmaceuticals in space. Most recently, the Pharmacology Risk Report, released in 2010, illustrates the problems associated with maintaining pharmaceutical efficacy. Since the report, one key publication includes evaluation of pharmaceutical products stored on the International Space Station (ISS). This study shows that selected pharmaceuticals on ISS have a shorter shelf-life in space than corresponding terrestrial controls. The HRP Human Research Roadmap for planetary exploration identifies the risk of ineffective or toxic medications due to long-term storage during missions to Mars. The roadmap also identifies the need to understand and predict how pharmaceuticals will behave when exposed to radiation for long durations. Terrestrial studies of returned samples offer a start for predictive modeling. This paper shows that pharmaceuticals returned to Earth for post-flight analyses are amenable to a Weibull distribution analysis in order to support probabilistic risk assessment modeling. The paper also considers the prospect of passive payloads of key pharmaceuticals on sample return missions outside of Earth's magnetic field to gather additional statistics. Ongoing work in radiation chemistry suggests possible mitigation strategies where future work could be done at cryogenic temperatures to explore methods for preserving the strength of pharmaceuticals in the space radiation environment, perhaps one day leading to an architecture where pharmaceuticals are cached on the Martian surface and preserved cryogenically.

pharmacology↗
NASA NTRS2016

Volatile Analysis by Pyrolysis of Regolith (Vapor) for Planetary Resource Prospecting

Measuring the chemical composition of planetary bodies and their atmospheres is key to understanding the formation of the Solar System and the evolution of the planets and their moons. In situ volatile measurements enable a ground-truth assessment of the distribution and abundance of resources such as water-ice and oxygen, important for a sustained human presence on the Moon and beyond. The Volatile Analysis by Pyrolysis of Regolith (VAPoR) instrument is a compact pyrolysis mass spectrometer designed to detect volatiles released from solid samples that are heated to elevated temperatures and is one technique that should be considered for resource prospecting on the Moon, Mars, and asteroids.

regolith↗
NASA NTRS2016

Resource Prospector: An Update on the Lunar Volatiles Prospecting and ISRU Demonstration Mission

Over the last two decades a wealth of new observations of the moon have demonstrated a lunar water system dramatically more complex and rich than was deduced following the Apollo era. Lunar water, and other volatiles, have the potential to be a valuable or enabling resource for future exploration. The NASA Human Exploration and Operations Mission Directorate (HEOMD) have selected a lunar volatiles prospecting mission for a concept study and potential flight in CY2021. The mission includes a rover-borne payload that (1) can locate surface and near-subsurface volatiles, (2) excavate and analyze samples of the volatile-bearing regolith, and (3) demonstrate the form, extractability and usefulness of the materials.

Human Exploration and Operations Mission Directora↗
NASA NTRS2017

Resource Prospector: An Update on the Lunar Volatiles Prospecting and ISRU Demonstration Mission

Over the last two decades a wealth of new observations of the moon have demonstrated a lunar water system dramatically more complex and rich than was deduced following the Apollo era. Lunar water, and other volatiles, have the potential to be a valuable or enabling resource for future exploration. The NASA Human Exploration and Operations Mission Directorate (HEOMD) have selected a lunar volatiles prospecting mission for a concept study and potential flight in CY2021. The mission includes a rover-borne payload that (1) can locate surface and near-subsurface volatiles, (2) excavate and analyze samples of the volatile- bearing regolith, and (3) demonstrate the form, extractability and usefulness of the materials.

Moon↗
NASA NTRS2017

Data Assimilation as it Relates to the Sea Ice Outlook (SIO) and Prospects for Improvement

Improved seasonal forecasts of Arctic sea ice are important for regional stakeholders, but also for obtaining a better understanding of the Arctic climate system. An important part of the forecasts is the initial sea ice, ocean, and atmosphere initial conditions. I briefly give an overview of the initial conditions currently being used in seasonal sea ice predictions. I also identify available sources of observational data and prospects for coupled atmosphere/ocean reanalyses.

Cullather, Richard↗
NASA NTRS2017

Prospective Architectures for Onboard vs Cloud-Based Decision Making for Unmanned Aerial Systems

This paper investigates propsective architectures for decision-making in unmanned aerial systems. When these unmanned vehicles operate in urban environments, there are several sources of uncertainty that affect their behavior, and decision-making algorithms need to be robust to account for these different sources of uncertainty. It is important to account for several risk-factors that affect the flight of these unmanned systems, and facilitate decision-making by taking into consideration these various risk-factors. In addition, there are several technical challenges related to autonomous flight of unmanned aerial systems; these challenges include sensing, obstacle detection, path planning and navigation, trajectory generation and selection, etc. Many of these activities require significant computational power and in many situations, all of these activities need to be performed in real-time. In order to efficiently integrate these activities, it is important to develop a systematic architecture that can facilitate real-time decision-making. Four prospective architectures are discussed in this paper; on one end of the spectrum, the first architecture considers all activities/computations being performed onboard the vehicle whereas on the other end of the spectrum, the fourth and final architecture considers all activities/computations being performed in the cloud, using a new service known as Prognostics as a Service that is being developed at NASA Ames Research Center. The four different architectures are compared, their advantages and disadvantages are explained and conclusions are presented.

Software engineering↗
NASA NTRS2020

Prospects for Interstellar Propulsion

In recognition of the increasing prospects for Earth-like exoplanet discoveries and its significance for spurring future interstellar voyages of discovery, the United States Congress recently directed NASA to undertake an interstellar mission technology assessment report. In response to this legislative charge to action, NASA has undertaken a series of extramural interstellar workshops aimed at identifying and evaluating technology concepts for enabling an interstellar scientific probe mission, associated technical challenges, technology readiness level assessments, risks, potential near-term milestones, and funding requirements. This paper summarizes these activities and discusses the scientific and technical rationale for a long-term program consisting of incremental, staged technical developments that are extensible for interstellar travel to a nearby star system over many decades.

Litchford, Ronald J.↗
NASA NTRS2019

The Lunar IceCube EM-1 Mission: Prospecting the Moon for Water Ice

Lunar IceCube is a NASA nanosatellite mission designed to prospect, locate, and measure volumes and composition of water ice deposits and other volatiles on the Moon in support of future exploitation by robots and human explorers. Lunar IceCube is one of several public -private partnerships selected under NASA's Next Space Technologies for Exploration Partnerships Broad Agency Announcement for the development of advanced exploration systems. Among the first small satellites planned to explore deep space, Lunar IceCube, along with the 12 other Exploration Mission One (EM -1) missions will help lay a foundation for future small-scale planetary missions. In addition to providing useful scientific data, Lunar IceCube will help inform NASA's strategy for sending humans farther into the solar system.

Benjamin K. Malphrus↗
NASA NTRSDate not supplied

Medical countermeasures for extraterrestrial environments: Current status and future prospects with focus on acute injuries

In all space exploratory activities involving humans there are associated risks to health and well-being. Exposure to ionizing radiation represents one of the more serious health concerns. Although medical issues can arise shortly following the rare acute exposures, the more likely radiation-associated injuries will manifest in a delayed fashion following sub-acute exposures or protracted exposures to relatively low radiation doses. The radiological conditions that present these health risks during extraterrestrial space travel are presented in this article, along with current physical and medical countermeasures for such exposure contingencies. The aim of this article is to discuss radiation medical countermeasures that may be considered for future space exploration and travel. Biomedical advances have occurred toward the control and minimization of acute, sub-acute, and fractionated radiation exposure injuries, whether they stem from intentional application of radio-therapeutic procedures or unintentional, accidental terrestrial-based exposures. Those advances, based largely on novel bioengineering, genetic, and combinatorial pharmaceutical strategies, are briefly reviewed here, along with the promising prospects of additional, new and improved medical countering systems/agents that will be forthcoming with additional research and development efforts.

Acute/chronic radiation injuries↗
NASA NTRSDate not supplied

High-Lift Prediction Workshops: Retrospective, Lessons Learned, and Future Prospects

A series of workshops focused on high lift, ongoing since 2010, is discussed. The series goal is to improve computational fluid dynamics prediction of high-lift flowfields, which has historically been very unreliable. The workshops center on CFD verification and validation exercises addressed in common by experts from organizations around the world, thereby enabling more rapid learning and improvement than would be possible with independent research alone. The workshop goals and structure are described, lessons learned to date are summarized, and potential future prospects for high-lift prediction are given.

high lift↗
NASA NTRSDate not supplied

Applied Uses of MERRA Reanalyses: Current and Future Prospects

During the initial planning of the Modern Era Retrospective-analysis for Research and Applications (MERRA), the project was envisioned to become a tool for applied sciences and decision makers, as well as weather and climate research. MERRA was the first reanalysis to provide data at 1 hourly frequencies. After discussions with wind energy users, 50m above the surface winds were included in the data collection to begin to represent the environment at the turbine height. MERRA-2 was the first reanalysis to include interactive and assimilated aerosols. From these, PM 1, 2.5 and 10 records have been computed and contribute to the climate and health sector. The US Center for Disease Control is accessing MERRA-2 data for comparison along with their health data. MERRA-2 Extreme Indices have been computed from the high frequency data (e.g. precipitation maxima, heat waves and fire weather). These have been used to characterize the changing extremes in the United States and around the globe as well as the weather associated with the extremes. The next-generation, MERRA-21C, includes increased resolution (25km) and continues to provide innovative Earth system data. For example, a boundary layer collection will provide constant height level data starting at 100m, continuing up to 4000m. This will provide detailed information about the boundary layer processes that greatly affect the biosphere. Chemical tracers for constituents are included in the system. The ensemble data assimilation is run with 32 members, and the variance for critical variables are stored. We will explore the use of this variance as one measure of uncertainty relevant for applied uses, which has not been included in any MERRA reanalysis. We will discuss use case scenarios developed to engage with the energy and financial sectors, to better understand their needs for climate data. Prospects for further downscaling of reanalyses will also be explored.

Michael Bosilovich↗
DOE OSTI2022

Projections of Environmental Impacts of Biofuels Across Scenarios Using Prospective LCA

This work showcases a collaboration between leading institutions focusing on integrated assessment modeling (IAM) and life cycle assessment (LCA), sponsored - among others - by the International Energy Agency's Technology Collaboration Program on Bioenergy, Task 45. It presents draft results of a prospective LCA for biofuels across world regions, using regional IAM scenario outputs, and life cycle inventories for country-specific pathways.

bioenergy↗
DOE OSTI2022

Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients

Increasing evidence shows that alterations in gut microbiome (GM) contribute to the development of type 2 diabetes mellitus (T2DM), and fecal microbiota transplantation (FMT) successfully treats various human diseases. However, the benefits of FMT therapy to T2DM patients remain unknown. We enrolled 17 patients with T2DM for nonblinded, one-armed intervention trial of FMT. A total of 20 healthy individuals were recruited as the baseline control. HbA1c% and metabolic parameter change were evaluated in 17 T2DM patients 12 weeks after they received FMT from healthy donors. The GM composition was characterized by 16S rRNA gene amplicon sequencing from fecal samples prior to and 12 weeks after FMT treatment. We found that the GM of T2DM patients was reconstituted by FMT. We observed a statistically significant decrease in HbA1c% (from 7.565 ± 0.148 to 7.190 ± 0.210, p<0.01), blood glucose (from 8.483 ± 0.497 to 7.286 ± 0.454 mmol/L, p<0.01), and uric acid (from 309.4 ± 21.5 to 259.1 ± 15.8 µmol/L, p<0.01) while a significant increase in postprandial C-peptide (from 4.503 ± 0.600 to 5.471 ± 0.728 ng/ml, p<0.01) at 12 weeks after FMT. Closely evaluating the changes in these assays, we found individual variability in response to FMT treatment. Out of 17 T2DM patients, 11 were found to significantly improve T2DM symptoms. The FMT responders have significantly higher levels of the family Rikenellaceae and the genus Anaerotruncus (family Ruminococcaceae) in their pretreated fecal in comparison to nonresponders, which could predict the clinical response with an area under the curve of 0.83. Our findings suggest that certain T2DM patients can potentially benefit from FMT, and the pretreated abundance of Rikenellaceae and Anaerotruncus in the fecal of patients may serve as potential biomarkers for selecting T2DM patients to receive FMT.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2022

Adapting Technology Learning Curves for Prospective Techno-Economic and Life Cycle Assessments of Emerging Carbon Capture and Utilization Pathways

Comparisons of emerging carbon capture and utilization (CCU) technologies with equivalent incumbent technologies are necessary to support technology developers and to help policy-makers design appropriate long-term incentives to mitigate climate change through the deployment of CCU. In particular, early-stage CCU technologies must prove their economic viability and environmental reduction potential compared to already-deployed technologies. These comparisons can be misleading, as emerging technologies typically experience a drastic increase in performance and decrease in cost and greenhouse gas emissions as they develop from research to mass-market deployment due to various forms of learning. These changes complicate the interpretation of early techno-economic assessments (TEAs) and life cycle assessments (LCAs) of emerging CCU technologies. The effects of learning over time or cumulative production themselves can be quantitatively described using technology learning curves (TLCs). While learning curve approaches have been developed for various technologies, a harmonized methodology for using TLCs in TEA and LCA for CCU in particular is required. To address this, we describe a methodology that incorporates TLCs into TEA and LCA to forecast the environmental and economic performance of emerging CCU technologies. This methodology is based on both an evaluation of the state of the art of learning curve assessment and a literature review of TLC approaches developed in various manufacturing and energy generation sectors. Additionally, we demonstrate how to implement this methodology using a case study on a CO 2 mineralization pathway. Finally, commentary is provided on how researchers, technology developers, and LCA and TEA practitioners can advance the use of TLCs to allow for consistent, high-resolution modeling of technological learning for CCU going forward and enable holistic assessments and fairer comparisons with other climate technologies.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗
DOE OSTI2022

Acoustic Properties of Aerogels: Current Status and Prospects

Noise reduction remains an important priority in the modern society, in particular, for urban areas and highly populated cities. Insulation of buildings and transport systems such as cars, trains, and airplanes has accelerated the need to develop advanced materials. Various porous materials, such as commercially available foams and granular and fibrous materials, are commonly used for sound mitigating applications. In this review, a special class of advanced porous materials, aerogels, is examined, and an overview of the current experimental and theoretical status of their acoustic properties is provided. Aerogels can be composed of inorganic matter, synthetic or natural polymers, as well as organic/inorganic composites and hybrids. Aerogels are highly porous nanostructured materials with a large number of meso‐ and small macropores; the mechanisms of sound absorption partly differ from those of traditional porous absorbers possessing large macropores. The understanding of the acoustic properties of aerogels is far from being complete, and experimental results remain scattered. It is demonstrated that the structure of the aerogel provides a complex three‐dimensional architecture ideally suited for promising high‐performance materials for acoustic mitigation systems. This is in addition to the numerous other desirable properties that include low density, low thermal conductivity, and low refractive index.

36 MATERIALS SCIENCE↗
DOE OSTI2023

Challenges and Prospects of All-Solid-State Electrodes for Solid-State Lithium Batteries

In the development of all-solid-state lithium batteries (ASSLB), progress is made with solid-state electrolytes; however, challenges regarding compatibility and stability still exist with solid electrodes. These issues result in a low battery capacity and short cycle life, which limit the commercial application of ASSLBs. Here, this review summarizes the recent research progress on solid-state electrodes in ASSLBs including the solid–solid interface phenomena such as the interface between electrode materials and electrolytes. The mechanical stability problems in solid electrodes, including fracture, brittleness, and deformation of electrode materials, are also discussed, and corresponding methods to measure the solid electrode stress are provided. In addition, strategies for mitigating stress-related issues are examined. Finally, the fabrication process of solid electrodes is introduced and their future developments, including the exploration of new electrode materials and the design of more intelligent electrode structures, are proposed.

25 ENERGY STORAGE↗