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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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This report describes the use of ComStock to model the implementation and impacts of upgrading the wall insulation, roof insulation, and windows in the U.S. commercial building stock to comply with the current state energy code in force.
State of the art stellar evolution codes [Paxton et al., 2010, Demarque et al., 2004, Weiss and Schlattl, 2008, Siess et al., 2013, Christensen-Dalsgaard, 2008] evoke a diffusive process to model convective overshooting. The diffusion coefficient [Freytag et al., 1996, Pratt et al., 2017] used in the model can be set to change with the classification of the convective zone as non-burning, H-burning, He-burning, or metal-burning. It can also be set to change at defined evolutionary points, such as the bottom of the asymptotic giant branch, or during the third dredge up [Herwig, 2000, Lugaro et al., 2003]. Aside from these abrupt changes, the diffusion coefficient is typically locked to a percentage of the pressure scale height measured at the convective boundary. However, there is no theoretical reason for convective overshooting, or indeed other convective properties, to change in the same way that the pressure scale height changes as a star evolves.
The primary objective of the present work was to investigate the potential impact of likely process variations on the nominal glass composition for LAW AP-107 waste that is determined by the LAW glass correlation (AP107WDFL). This was accomplished by evaluating glass and feed variations at crucible scale and DM100 melter tests.
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Performance metrics serve as useful tools and indicators for many applications. For the building industry, various metrics exist; typically, these metrics do not assess the whole building performance. Instead, these represent separate components or heat transfer mechanisms of a building like R-value, U-factor/value, and airtightness. The mechanisms defined under these metrics all contribute significantly to the overall thermal performance of a building but will rarely act independently. There are metrics that account for the overall energy performance of a building, such as Energy Use Intensity (EUI). However, these metrics tend to be highly influenced by how the building is operated and used. There are also metrics which provide assessment on a relative basis. These indices are based upon comparison to a baseline, which complicates meaningful metric-based energy analyses. This paper presents a performance metric developed to account for various thermal properties and behaviors of a building. The metric accounts for all the relevant mechanisms that influence heat losses and gains in buildings and is thus directly related to the energy performance. In addition, the metric is designed to comprise air infiltration and allows users to account for workmanship quality, and imperfections of the building thermal resistance due to penetrations and other installations. This paper will describe how the metric can be applied for various building types and in different climates.
We recently demonstrated that Simian–HIV (SHIV)-infected neonate rhesus macaques (RMs) generated heterologous HIV-1 neutralizing antibodies (NAbs) with broadly-NAb (bNAb) characteristics at a higher frequency compared with their corresponding dam. Here, we characterized genetic diversity in Env sequences from four neonate or adult/dam RM pairs: in two pairs, neonate and dam RMs made heterologous HIV-1 NAbs; in one pair, neither the neonate nor the dam made heterologous HIV-1 NAbs; and in another pair, only the neonate made heterologous HIV-1 NAbs. Phylogenetic and sequence diversity analyses of longitudinal Envs revealed that a higher genetic diversity, within the host and away from the infecting SHIV strain, was correlated with heterologous HIV-1 NAb development. We identified 22 Env variable sites, of which 9 were associated with heterologous HIV-1 NAb development; 3/9 sites had mutations previously linked to HIV-1 Env bNAb development. These data suggested that viral diversity drives heterologous HIV-1 NAb development, and the faster accumulation of viral diversity in neonate RMs may be a potential mechanism underlying bNAb induction in pediatric populations. Moreover, these data may inform candidate Env immunogens to guide precursor B cells to bNAb status via vaccination by the Env-based selection of bNAb lineage members with the appropriate mutations associated with neutralization breadth.
The Transient Reactor Test (TREAT) Facility is an air-cooled reactor composed of graphite-urania fuel encapsulated in zirconium alloy canisters and surrounded by ~2 ft (~61 cm) of nuclear grade graphite. The primary role of TREAT is to provide in-pile nuclear-heated safety research via transient testing [1]. The following work represents further analyses building upon previously reported work to support larger volume test vehicles within TREAT [2]. The Broad Use Specimen Transient Experiment Rig (BUSTER) provides ample versatility for numerous transient test concepts. However, future testing and experiment needs will require testing environments of different in-core footprints. The versatility of TREAT allows for the development of variegated core layouts with key limitations emplaced as operational safety temperature restrictions and available core reactivity. The focus of this current effort is to gauge core arrangements for TREAT core loadings to support centralized experimental testing of varying dimensional capacity. The total core excess reactivity (ER) was computed for different arrangements to establish comparison tables that enable ready assessment of core ER available for future experiment concepts. Test vehicle worths would then be necessary to establish available ER to support transient testing requirements and to perform reactor performance and safety calculations [3,4].
The present invention relates, in general, to human immunodeficiency virus-1 (HIV-1) particular, to a polyvalent vaccine for HIV-1 and to methods of making and using same.
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Abstract not provided.
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A gasket assembly for attaching a window to a panel opening includes an inner frame, an outer frame, and an elastic material connecting the inner frame to the outer frame. The elastic material extends contiguously and circumferentially to couple the outer frame to the inner frame. The outer frame and inner frame can include gap flanges and the elastic material can include opposing lateral side portions. The gap flanges are embedded in the lateral side portions of the elastic material. The outer frame includes connecting structure for coupling of the outer frame to the panel opening. The inner frame includes a connecting structure for coupling of the gasket assembly to the window. The gasket assembly is configured to support the window in the panel opening and form a seal between the panel opening and the window. A method of making a gasket assembly is also disclosed.
The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.
The present disclosure relates to a directional heat transfer using thermal control devices, including a dual phase change thermal diode and an active contact-based thermal switch. The thermal diode includes a positive temperature coefficient switching material and a negative temperature coefficient switching material arranged in series. The thermal switch includes two thermally conducting surfaces which may be moved to contact (i.e., having a distance between them of substantially zero) creating minimal thermal contact resistance. Both thermal control devices may be used to control heat flow into and/or out of a building.
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