Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “transition operator”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 217 records · Page 12

Mission Level Autonomy for USSV

On-water demonstration of a wide range of mission-proven, advanced technologies at TRL 5+ that provide a total integrated, modular approach to effectively address the majority of the key needs for full mission-level autonomous, cross-platform control of USV s. Wide baseline stereo system mounted on the ONR USSV was shown to be an effective sensing modality for tracking of dynamic contacts as a first step to automated retrieval operations. CASPER onboard planner/replanner successfully demonstrated realtime, on-water resource-based analysis for mission-level goal achievement and on-the-fly opportunistic replanning. Full mixed mode autonomy was demonstrated on-water with a seamless transition between operator over-ride and return to current mission plan. Autonomous cooperative operations for fixed asset protection and High Value Unit escort using 2 USVs (AMN1 & 14m RHIB) were demonstrated during Trident Warrior 2010 in JUN 2010

maritime autonomy↗

The Detection, Characterization and Tracking of Recent Aleutian Island Volcanic Ash Plumes and the Assessment of Their Impact on Aviation

The Aleutian Islands of Alaska are home to a number of major volcanoes which periodically present a significant hazard to aviation. During summer of 2008, the Okmok and Kasatochi volcanoes experienced moderate eruptive events. These were followed a dramatic, major eruption of Mount Redoubt in late March 2009. The Redoubt case is extensively covered in this paper. Volcanic ash and SO2 from each of these eruptions dispersed throughout the atmosphere. This created the potential for major problems for air traffic near the ash dispersions and at significant distances downwind. The NASA Applied Sciences Weather Program implements a wide variety of research projects to develop volcanic ash detection, characterization and tracking applications for NASA Earth Observing System and NOAA GOES and POES satellites. Chemistry applications using NASA AURA satellite Ozone Monitoring System (OMI) retrievals produced SO2 measurements to trace the dispersion of volcanic aerosol. This work was complimented by advanced multi-channel imager applications for the discrimination and height assignment of volcanic ash using NASA MODIS and NOAA GOES and POES imager data. Instruments similar to MODIS and OMI are scheduled for operational deployment on NPOESS. In addition, the NASA Calipso satellite provided highly accurate measurements of aerosol height and dispersion for the calibration and validation of these algorithms and for corroborative research studies. All of this work shortens the lead time for transition to operations and ensures that research satellite data and applications are operationally relevant and utilized quickly after the deployment of operational satellite systems. Introduction

Murray, John J.↗

OB200-DV-1 Treatability Testing: Final Results

The Hanford Site in Washington state previously generated plutonium for nuclear weapons. During operations, radionuclide byproducts and chemical process fluids were intentionally and/or unintentionally released to the subsurface, resulting in more than 800 contaminated waste sites across the Central Plateau, where historical chemical separations and waste management activities took place. As the Hanford Site mission transitioned from operations to site cleanup, remediation of the vadose zone and groundwater became a priority. However, given the depth of the unsaturated zone contamination above the groundwater, the unique nature of the waste, and the continuing impacts on groundwater quality, technologies needed to be identified and evaluated for in situ remediation in the deep vadose zone (DVZ). A laboratory treatability study has been completed to evaluate site-relevant effectiveness for nine in situ technologies that may be used to treat continuing sources of contaminants in specific areas of the Central Plateau waste sites that are grouped into the 200-DV-1 Operable Unit (OU). The 200-DV-1 OU was established in 2010 to address 43 Central Plateau waste sites with complex DVZ remediation challenges. Eight of these technologies were identified through a prescreening effort that evaluated remedial technologies potentially applicable to DVZ contamination in the Central Plateau . These eight technologies were selected for further study based on site specific knowledge gaps about their effectiveness. A ninth technology was added to the treatability study based on new information from separate laboratory investigations (conducted following the prescreening effort) demonstrating the technology’s potential effectiveness (see Section 1.2 for more information) and value for inclusion in the treatability study.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Cyberinfrastructure for Airborne Sensor Webs

Since 2004 the NASA Airborne Science Program has been prototyping and using infrastructure that enables researchers to interact with each other and with their instruments via network communications. This infrastructure uses satellite links and an evolving suite of applications and services that leverage open-source software. The use of these tools has increased near-real-time situational awareness during field operations, resulting in productivity improvements and the collection of better data. This paper describes the high-level system architecture and major components, with example highlights from the use of the infrastructure. The paper concludes with a discussion of ongoing efforts to transition to operational status.

Freudinger, Lawrence C.↗

Addendum to "Impressed Sources and Fields in the Volume-Integral-Equation Formulation of Electromagnetic Scattering by a Finite Object: A Tutorial"

Our recent tutorial referred to in the title has summarized a general theoretical formalism of electromagnetic scattering by an arbitrary finite object in the presence of arbitrarily distributed impressed currents. This addendum builds on the tutorial to provide a streamlined discussion of specific far-field limits and the corresponding reciprocity relations by introducing appropriate far-field operators and linear maps and deriving the reciprocity relations through the pseudo adjoint of these maps. We thereby extend the compact operator calculus used previously to consider the fields and sources near or inside the scattering object.

Impressed Sources↗

TASAR Certification and Operational Approval Requirements - Analyses and Results

This report documents the results of research and development work performed by Rockwell Collins in addressing the Task 1 objectives under NASA Contract NNL12AA11C. Under this contract Rockwell Collins provided analytical support to the NASA Langley Research Center (LaRC) in NASA's development of a Traffic Aware Strategic Aircrew Requests (TASAR) flight deck Electronic Flight Bag (EFB) application for technology transition into operational use. The two primary objectives of this contract were for Rockwell Collins and the University of Iowa OPL to 1) perform an implementation assessment of TASAR toward early certification and operational approval of TASAR as an EFB application (Task 1 of this contract), and 2) design, develop and conduct two Human-in-the-Loop (HITL) simulation experiments that evaluate TASAR and the associated Traffic Aware Planner (TAP) software application to determine the situational awareness and workload impacts of TASAR in the flight deck, while also assessing the level of comprehension, usefulness, and usability of the features of TAP (Task 2 of this contract). This report represents the Task 1 summary report. The Task 2 summary report is provided in [0].

Koczo, Stefan, Jr.↗

Performance Evaluation of a Single-Phase Grid-Forming Inverter Through Hardware Experiments

This study conducts hardware experiments to assess the performance of a commercial single-phase grid-forming (GFM) inverter using a purely hardware-based approach. We adhere to a testing protocol for the GFM inverter and enhance it by exploring the transient performance of GFM inverters across various grid dynamic events. Quantifiable performance metrics are established for each testing scenario to gain insights into the performance of the single-phase GFM inverters. Based on the comprehensive tests, the following observations are summarized: 1) The performance of the single-phase GFM inverter is satisfactory, and it is capable of being the islanding master for residence homes when the main grid is gone. 2) For frequency response, the inverter is able to stay connected but cannot inject the needed active power to support the grid. This may be improved by the manufacturer by using droop control. 3) The GFM inverter exhibits harmful transients in voltage and frequency during islanding operation, which can be enhanced by maintaining the same operating points before and after the breaker is open.

dynamic performance↗

Space Station Freedom - Configuration management approach to supporting concurrent engineering and total quality management

Some experiences of NASA configuration management in providing concurrent engineering support to the Space Station Freedom program for the achievement of life cycle benefits and total quality are discussed. Three change decision experiences involving tracing requirements and automated information systems of the electrical power system are described. The potential benefits of concurrent engineering and total quality management include improved operational effectiveness, reduced logistics and support requirements, prevention of schedule slippages, and life cycle cost savings. It is shown how configuration management can influence the benefits attained through disciplined approaches and innovations that compel consideration of all the technical elements of engineering and quality factors that apply to the program development, transition to operations and in operations. Configuration management experiences involving the Space Station program's tiered management structure, the work package contractors, international partners, and the participating NASA centers are discussed.

Gavert, Raymond B.↗

Synergistic and Collaborative Development Strategies for FV3 Powered Next Generation Unified Global Modeling System

The GFDL (Geophysical Fluid Dynamics Laboratory, NOAA - National Oceanic and Atmospheric Administration) Finite-­Volume Cubed-Sphere Dynamical Core (FV3) is a scalable and flexible dynamical core capable of both hydrostatic and non-hydrostatic atmospheric simulations. FV3 has been chosen as the dynamical core for the Next Generation Global Prediction System project (NGGPS), designed to upgrade the current NCEP (National Centers for Environmental Prediction, NOAA) operational Global Forecast System (GFS) to run as a unified, fully-coupled system in NOAA's Environmental Modeling System infrastructure. FV3 dynamic core has a long history of serving as the main engine for global atmospheric models at various Government and Academic Research Laboratories including NOAA: GFDL Climate Modeling Suite (AM4 (Atmosphere Modeling 4), CM4 (Climate Model 4) ESM4 (Earth System Model 4), Hiram (HIgh Resolution Atmospheric Model)); NASA: GMAO (Global Modeling and Assimilation Office) Goddard Earth Observing System Model (GEOS); and NCAR (National Center for Atmospheric Research) Community Earth System Model (CESM). The three primary stakeholders in FV3 (GFDL, GMAO, EMC (Environmental Modeling Center - NOAA)) have embarked on synergistic and collaborative strategies with focus on the advancement of non-hydrostratic dynamic core, physics, chemistry, and data assimilation efforts, leveraging collective strengths of each of the partnering agencies. This talk presents the ongoing plans for model advancements at GFDL, GMAO and EMC, with special emphasis on contributions towards developing community based unified global modeling system for operational and research applications at respective organizations. Future plans include extending the collaborations to the development of earth system components including GMAO's aerosol chemistry models (GOCART/MAM (Goddard Chemistry Aerosol Radiation and Transport / Modal Aerosol Model)), Land Information System (LIS), and advanced data assimilation techniques; and GFDL's Modular Ocean Model (MOM) and Sea Ice Simulator (SIS) for transition to operations at NCEP.

Putman, William↗

Expanding the Time Dimension of Hyperspectral Infrared Sounding Observations: Designing the NUCAPS-Forecast System

Low Earth orbit (LEO) hyper-spectral infrared (IR) sounders have significant yet untapped potential for characterizing thermodynamic environments of convective initiation and ongoing convection. While LEO soundings are of enormous value to weather forecasters, they cannot provide the temporal resolution needed to resolve the rapidly evolving thermodynamics of the convective environment. A novel methodology was developed to extend snapshots of LEO soundings forward in time up to six hours into the future and has been made available within the NOAA National Weather Service Advanced Weather Interactive Processing System (AWIPS) for testing in a quasi-operational setting. This methodology is based on parcel forward-trajectory calculations from the satellite observing time to recreate future soundings of temperature and moisture at regularly gridded intervals in space and time. The soundings are based on NOAA-Unique Combined Atmospheric Processing System (NUCAPS) retrievals from the Suomi NPP and NOAA-20 satellite platforms to allow for rapid near-real time product processing. Science code was transitioned to operational production in 2019 and the product, NUCAPS-Forecast, was tested at the NOAA Hazardous Weather Testbed Spring Experiment in 2019 and 2021. Forecaster feedback has led to improving the product and processing system to address product limitations and improve its applicability for pre-convective forecasting. This presentation highlights the design of the NUCAPS-Forecast system. Solutions were tested and implemented to remove excess moisture and conjoin forward-trajected parcels into vertical profiles for calculating grids of stability indices. Additionally, use cases that explore the tendencies of derived convective available potential energy (CAPE) and convective inhibition (CIN) were investigated. When evaluated against gridded, hourly accumulated rainfall obtained from the Multi-Radar Multi-Sensor (MRMS) observational data set areas with elevated CAPE (reduced CIN) are shown to be associated with areas of precipitation and increase confidence the LEO soundings advected forward in time physically represent atmospheric processes. These results suggest that adiabatic parcel advection of LEO satellite sounding snapshots forward in time exhibits skill in discriminating locations and times that are more likely to lead to convective initiation. Leveraging trajectory modeling to increase the spatial and temporal resolution of LEO IR sounding observations today demonstrates the value of these observations from the future constellation of JPSS satellites and GeoXO mission.

weather↗

Subject Matter Expert Evaluation of Multi-Flight Common Route Advisories

Traffic flow management seeks to balance the demand for National Airspace System (NAS) flight resources, such as airspace and airports, with the available supply. When forecasted weather blocks nominal air traffic routes, traffic managers must re-route affected flights for weather avoidance. Depending on the nature and scope of the weather, traffic managers may use pre-coordinated re-routes such as Playbook Routes or Coded Departure Routes, or may design ad hoc local re-routes. The routes of affected flights are modified accordingly. These weather avoidance routes will, of course, be less efficient than the nominal routes due to increased flight time and fuel burn. In current traffic management operations, the transition into a weather avoidance re-routing initiative is typically implemented more aggressively than the transition out of that initiative after the weather has dissipated or moved away. For example, strategic large-scale Playbook re-routes are sometimes left in place (as initially implemented) for many hours before being lifted entirely when the weather dissipates. There is an opportunity to periodically modify the re-routing plan as weather evolves, thereby attenuating its adverse impact on flight time and fuel consumption; this is called delay recovery. Multi-Flight Common Routes (MFCR) is a NASA-developed operational concept and associated decision support tool for delay recovery, designed to assist traffic managers to efficiently update weather avoidance traffic routes after the original re-routes have become stale due to subsequent evolution of the convective weather system. MFCR groups multiple flights to reduce the number of advisories that the traffic manager needs to evaluate, and also merges these flights on a common route segment to provide an orderly flow of re-routed traffic. The advisory is presented to the appropriate traffic manager who evaluates it and has the option to modify it using MFCRs graphical user interface. If the traffic manager finds the advisory to be operationally appropriate, he or she would coordinate with the Area Supervisor(s) of the sectors that currently control the flights in the advisory. When the traffic manager accepts the MFCR advisory via the user interface, the corresponding flight plan amendments would be sent to the displays of the appropriate sector controllers, using the Airborne Re-Routing (ABRR) capability which is scheduled for nationwide operation in 2017. The sector controllers would then offer this time-saving route modification to the pilots of the affected flights via datalink (or voice), and implement the corresponding flight plan amendment if the pilots accept it. MFCR is implemented as an application in the software environment of the Future Air traffic management Concepts Evaluation Tool (FACET). This paper focuses on an initial subject matter expert (SME) evaluation of MFCR. The evaluation covers MFCRs operational concept, algorithm, and user interface.

Human-in-the-loop Evaluation↗

Subject Matter Expert Evaluation of Multi-Flight Common Route Advisories

Traffic flow management seeks to balance the demand for National Airspace System (NAS) flight resources, such as airspace and airports, with the available supply. When forecasted weather blocks nominal air traffic routes, traffic managers must re-route affected flights for weather avoidance. Depending on the nature and scope of the weather, traffic managers may use pre-coordinated re-routes such as Playbook Routes or Coded Departure Routes, or may design ad hoc local re-routes. The routes of affected flights are modified accordingly. These weather avoidance routes will, of course, be less efficient than the nominal routes due to increased flight time and fuel burn. In current traffic management operations, the transition into a weather avoidance re-routing initiative is typically implemented more aggressively than the transition out of that initiative after the weather has dissipated or moved away. For example, strategic large-scale Playbook re-routes are sometimes left in place (as initially implemented) for many hours before being lifted entirely when the weather dissipates. There is an opportunity to periodically modify the re-routing plan as weather evolves, thereby attenuating its adverse impact on flight time and fuel consumption; this is called delay recovery. Multi-Flight Common Routes (MFCR) is a NASA-developed operational concept and associated decision support tool for delay recovery, designed to assist traffic managers to efficiently update weather avoidance traffic routes after the original re-routes have become stale due to subsequent evolution of the convective weather system. MFCR groups multiple flights to reduce the number of advisories that the traffic manager needs to evaluate, and also merges these flights on a common route segment to provide an orderly flow of re-routed traffic. The advisory is presented to the appropriate traffic manager who evaluates it and has the option to modify it using MFCRs graphical user interface. If the traffic manager finds the advisory to be operationally appropriate, he or she would coordinate with the Area Supervisor(s) of the sectors that currently control the flights in the advisory. When the traffic manager accepts the MFCR advisory via the user interface, the corresponding flight plan amendments would be sent to the displays of the appropriate sector controllers, using the Airborne Re-Routing (ABRR) capability which is scheduled for nationwide operation in 2017. The sector controllers would then offer this time-saving route modification to the pilots of the affected flights via datalink (or voice), and implement the corresponding flight plan amendment if the pilots accept it. MFCR is implemented as an application in the software environment of the Future Air traffic management Concepts Evaluation Tool (FACET). This paper focuses on an initial subject matter expert (SME) evaluation of MFCR. The evaluation covers MFCRs operational concept, algorithm, and user interface.

Traffic flow management↗

The TESS Science Processing Operations Center

The Transiting Exoplanet Survey Satellite (TESS) will conduct a search for Earth’s closest cousins starting in late 2017. TESS will discover approx.1,000 small planets and measure the masses of at least 50 of these small worlds. The Science Processing Operations Center (SPOC) is being developed based on the Kepler science pipeline and will generate calibrated pixels and light curves on the NAS Pleiades supercomputer. The SPOC will search for periodic transit events and generate validation products for the transit-like features in the light curves. All TESS SPOC data products will be archived to the Mikulski Archive for Space Telescopes.

TESS↗

Exploration Medical Capability - Advancing Medical System Design and Risk-Informed Decision Making for Deep Space Exploration

BACKGROUND: Within NASA’s Human Research Program, the Exploration Medical Capability (ExMC) Element has three primary focus areas: clinical and scientific research, systems engineering and trade space analysis, and technology development and demonstrations. These focus areas feed into the overarching goal of enabling progressively Earth-Independent Medical Operations (EIMO), a new paradigm that will be necessary for future Artemis and Mars medical and vehicle systems. This EIMO end state aligns with NASA’s Moon to Mars Objectives, which clearly outline the need for NASA deep space exploration missions to reduce their reliance upon Earth and become increasingly autonomous, in preparation for the first human Mars mission. OVERVIEW: To advance exploration medical systems and ultimately, integrated crew health and performance systems, ExMC’s portfolio includes: funding ground development & testing of novel medical capabilities; creation of new approaches for the development of medical protocols and procedures; deployment of innovative technologies into analog environments; technology demonstrations in spaceflight; and eventual transition to operations of new capabilities for deep space exploration missions. The portfolio also includes: pharmaceutical research targeting stability, pharmacokinetics, and pharmacodynamics; integrated data architectures and clinical decision support tools; and systems engineering and trade space analysis tools to assist NASA in the development of future medical system models as well as the medical system requirements that can serve as a foundation for deep space exploration missions. All of these investments are done in a collaborative and coordinated fashion with other NASA stakeholders, such as the Environmental Control and Life Support Systems – Crew Health and Performance System Capability Leadership Team and the Health and Medical Technical Authority. DISCUSSION: In this presentation, ExMC will provide an overview of our work from across our portfolio, all of which will inform future EIMO efforts at NASA. ExMC’s research and development investments are targeted to reduce the human system risks associated with deep space exploration to the Moon and Mars.

Kris Lehnhardt↗

Speech Alarms Pilot Study

Currently on the International Space Station (ISS) and other space vehicles Caution & Warning (C&W) alerts are represented with various auditory tones that correspond to the type of event. This system relies on the crew's ability to remember what each tone represents in a high stress, high workload environment when responding to the alert. Furthermore, crew receive a year or more in advance of the mission that makes remembering the semantic meaning of the alerts more difficult. The current system works for missions conducted close to Earth where ground operators can assist as needed. On long duration missions, however, they will need to work off-nominal events autonomously. There is evidence that speech alarms may be easier and faster to recognize, especially during an off-nominal event. The Information Presentation Directed Research Project (FY07-FY09) funded by the Human Research Program included several studies investigating C&W alerts. The studies evaluated tone alerts currently in use with NASA flight deck displays along with candidate speech alerts. A follow-on study used four types of speech alerts to investigate how quickly various types of auditory alerts with and without a speech component - either at the beginning or at the end of the tone - can be identified. Even though crew were familiar with the tone alert from training or direct mission experience, alerts starting with a speech component were identified faster than alerts starting with a tone. The current study replicated the results from the previous study in a more rigorous experimental design to determine if the candidate speech alarms are ready for transition to operations or if more research is needed. Four types of alarms (caution, warning, fire, and depressurization) were presented to participants in both tone and speech formats in laboratory settings and later in the Human Exploration Research Analog (HERA). In the laboratory study, the alerts were presented by software and participants were asked to identify the alert as quickly and as accurately as possible. Reaction time and accuracy were measured. Participants identified speech alerts significantly faster than tone alerts. The HERA study investigated the performance of participants in a flight-like environment. Participants were instructed to complete items on a task list and respond to C&W alerts as they occurred. Reaction time and accuracy were measured to determine if the benefits of speech alarms are still present in an applied setting.

Sandor, A.↗

Design of a Two-Body Wave Energy Converter Featuring Controllable Geometry

While the field of wave energy has been the subject of numerical simulation, scale model testing, and precommercial project testing for decades, wave energy technologies remain in the early stages of development and must continue to prove themselves as a promising modern renewable energy field. A wave energy converter (WEC) concept currently being explored is the variable-geometry WEC (VGWEC), which aims to add an extra control option to WEC design. VGWECs attempt to incorporate controllable geometric features to adjust the floating body hydrodynamics to favor either power absorption, load shedding, or other operational goals. These variable geometry components have been proposed to be controlled on a sea-state-to-sea-state or wave-to-wave time scale depending on the force (or torque) and bandwidth limitations of the actuators required to manipulate just the controllable geometric hull features. Having control over both the WEC geometry components and the power takeoff (PTO) offers the potential to improve overall system performance and reliability if a cost-effective solution can be found for a given WEC architecture. This paper will present the recent developments and results of a VGWEC concept that incorporates variable-geometry modules into a two-body WEC. In the proposed VGWEC concept, the variable-geometry modules consist of air-inflatable bags in the surface float and a water inflatable ring in the subsurface body. The surface float is tethered directly to the subsurface body through tether lines, each connected to a separate PTO. Adjusting the geometry of both the surface and subsurface bodies along with the PTO coefficients can maximize power in design sea states while reducing motion response and PTO forces when transitioning to sea states where rated power is reached and load shedding is prioritized. The ability to transition between operating condition is expected to increase the sea state operational map and power capacity.

geometry control↗

An Environmental and Societal Analysis of the US Electrical Energy Industry Based on the Water–Energy Nexus

To meet rising energy demands, power plant operations will expand, influencing the interactions between the water–energy nexus and society. However, a major challenge is integration of social dimensions within electricity generation. To address this, we generate a baseline dataset using US public data (2014–2019) from the Energy Information Administration and US Bureau of Labor Statistics. We identify the rate of energy consumed, CO 2 , SO 2 and NO x emissions generated, and water used per MWh net electricity as well as employee wellbeing per unit MW capacity during electricity generation. Rates of energy consumption (MMBtu/MWh) decreased 4.9%, but water consumption and withdrawal (m 3 /MWh) both increased 0.93% and 0.31%, respectively. Emissions of CO 2 , SO 2 and NO x decreased 22.64%, 75% and 25% MT/MWh, respectively. Thermoelectric cooling withdrawal and consumption is led by natural gas (50.07%, 38.31%), coal (29.61%, 25.07%), and nuclear energies (13.55%, 18.99%). Electric power generation contributes 0.06 injuries–illnesses/TWh and 0.001 fatalities/TWh, of which fossil fuels contributed 70% and 15%, respectively. Fossil fuels led in average annual employment (0.02 employees/MW) with low cost salaries (USD 0.09/MW) likely due to high collective capacity, which is declining. Estimated rates in this study and framework will aid power industry transition and operational decision makers.

24 POWER TRANSMISSION AND DISTRIBUTION↗

MS Non-Pharmacological Countermeasure to Decrease Landing Sickness and Improve Functional Performance While Disorientad

Upon return from spaceflight, a majority of crewmembers experience motion sickness (MS) symptoms. The interactions between crewmembers' adaptation to a gravitational transition, the performance decrements resulting from MS and/or use of promethazine (PMZ), and the constraints imposed by mission task demands could significantly challenge and limit an astronaut's ability to perform functional tasks during gravitational transitions. No operational countermeasure currently exists to mitigate the risks associated with these sensorimotor disturbances. Stochastic resonance (SR) can be thought of simply as "noise benefit" or an increase in information transfer by a system when in the presence of a non-zero level of noise. We have shown that low levels of stochastic vestibular stimulation (SVS) improve balance and locomotor performance due to SR (Goel et al. 2015, Mulavara et al. 2011, 2015). Additionally, a study in a 6-hydroxydopamine (6-OHDA) hemi-lesioned rat model of Parkinson's disease demonstrated improvements in locomotor activity after low-level SVS delivery possibly due to an increase in nigral gamma-aminobutyric acid (GABA) release in a dopamine independent way (Samoudi et al. 2012). SVS specifically increased GABA release on the lesioned, but not the intact side. These results suggest that SVS can cause targeted alterations of GABA release to affect performance of functional tasks. Activation of the GABA pathway is important in modulating MS and promoting adaptability (Cohen 2008). Magnusson et al. (2000) supported this finding by showing that the administration of a GABAB agonist caused a reversal of the symptoms that is normally seen after unilateral labyrinthectomy. Thus, GABA could play a significant role in reducing MS and promoting adaptability. We have taken advantage of the SR mechanism as a modulator of neurotransmitters to develop a unique SVS countermeasure system to mitigate MS symptoms and improve functional performance after landing. Healthy subjects (n=20) participated in two test sessions, one in which they received +/-400 microA of SVS and one where they received no stimulation (0 microA); the study design was counterbalanced. Subjects began by performing a series of four functional tasks 3-5 times as baseline measurements of task performance. Then, to induce MS, subjects walked an obstacle course with up-down reversing prisms. If they completed the course before achieving our pre-determined level of MS, they were asked to read a poster while making large up-down head movements to a metronome while still wearing the reversing prism goggles. Subjects were stopped every two minutes and asked to report their MS symptoms. Using the Pensacola Scale for motion sickness, test operators evaluated the level of MS of each subject. Once a subject reached an 8 on this scale, which is equivalent to mild malaise, or 30 minutes had passed since the start of the MS induction, this protocol was stopped. Finally, immediately after MS induction, subjects were asked to complete the four functional tasks again. Although, 100% of our subjects experienced at least one MS symptom, only 55% of our subjects experienced stomach awareness to any degree. Without SVS, only 40% of subjects lasted the full 30-minute MS induction protocol, while 65% of subjects lasted the full 30 minutes with SVS, which is nearly a significant increase (p=0.056). In addition, subjects showed significant improvement from baseline when performing a tandem walk and a prone-to-stand test immediately after the MS induction protocol was stopped but the stimulation level was continued. The results are promising and future work includes comparing MS progression between PMZ and SVS directly in subjects that are provoked to a minimum of nausea. Low levels of SVS stimulation may serve as a non-pharmacological countermeasure to replace or reduce the PMZ dosage requirements and concurrently improve functional performance during transitions to new gravitational environments after spaceflight.

Rosenberg, M. J. F.↗